In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material

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C12N15/1024

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N15/00Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors

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C12N15/1024In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material

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Patents Grantslast 30 patents

Information Patent Grant
Yeast with improved alcohol production under high dissolved solids...
- Patent number 12,139,704
- Issue date Nov 12, 2024
- Danisco US Inc.
- Celia Emily Gaby Payen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-guided human genome engineering
- Patent number 12,018,272
- Issue date Jun 25, 2024
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and products for expressing proteins in cells
- Patent number 12,006,508
- Issue date Jun 11, 2024
- Factor Bioscience Inc.
- Matthew Angel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Adenosine nucleobase editors and uses thereof
- Patent number 11,999,947
- Issue date Jun 4, 2024
- President and Fellows of Harvard College
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nuclease-based RNA depletion
- Patent number 11,976,271
- Issue date May 7, 2024
- Illumina, Inc.
- Scott Kuersten
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Adenine DNA base editor variants with reduced off-target RNA editing
- Patent number 11,946,040
- Issue date Apr 2, 2024
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method to screen for a mutant within a population of organisms by a...
- Patent number 11,884,972
- Issue date Jan 30, 2024
- CARLSBERG A/S
- Toni Wendt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Electroporation, developmentally-activated cells, pluripotent-like...
- Patent number 11,859,168
- Issue date Jan 2, 2024
- Christopher B. Reid
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for the targeted modification of a genome
- Patent number 11,820,997
- Issue date Nov 21, 2023
- REGENERON PHARMACEUTICALS, INC.
- David Frendewey
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CRISPR enabled multiplexed genome engineering
- Patent number 11,795,479
- Issue date Oct 24, 2023
- The Regents of the University of Colorado
- Andrew Garst
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Repairing compound heterozygous recessive mutations by allele exchange
- Patent number 11,773,410
- Issue date Oct 3, 2023
- University of Massachusetts
- Guangping Gao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Kinase mutants and uses thereof
- Patent number 11,738,049
- Issue date Aug 29, 2023
- SIB Swiss Institute of Bioinformatics
- Olivier Michielin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Genomic sequence modification method for specifically converting nu...
- Patent number 11,718,846
- Issue date Aug 8, 2023
- National University Corporation Kobe University
- Keiji Nishida
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
CRISPR enabled multiplexed genome engineering
- Patent number 11,702,677
- Issue date Jul 18, 2023
- The Regents of the University of Colorado
- Andrew Garst
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Adenosine nucleobase editors and uses thereof
- Patent number 11,702,651
- Issue date Jul 18, 2023
- President and Fellows of Harvard College
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for producing RNA molecule compositions
- Patent number 11,684,665
- Issue date Jun 27, 2023
- CureVac SE
- Tilmann Roos
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Platform for developing stable mammalian cell lines
- Patent number 11,685,936
- Issue date Jun 27, 2023
- Icosagen Cell Factory OÜ
- Kadri Õunap
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-guided endonuclease fusion polypeptides and methods of use thereof
- Patent number 11,649,442
- Issue date May 16, 2023
- The Regents of the University of California
- Schaked Omer Halperin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-guided endonuclease fusion polypeptides and methods of use thereof
- Patent number 11,649,443
- Issue date May 16, 2023
- The Regents of the University of California
- Schaked Omer Halperin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CRISPR enabled multiplexed genome engineering
- Patent number 11,639,511
- Issue date May 2, 2023
- The Regents of the University of Colorado, a Body Corporate
- Andrew Garst
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for the site-specific enzymatic labelling of nucleic acids i...
- Patent number 11,634,451
- Issue date Apr 25, 2023
- The Scripps Research Institute
- Floyd E. Romesberg
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Single-stranded oligonucleotide
- Patent number 11,555,188
- Issue date Jan 17, 2023
- NISSAN CHEMICAL CORPORATION
- Yusuke Iriyama
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-guided human genome engineering
- Patent number 11,535,863
- Issue date Dec 27, 2022
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-guided human genome engineering
- Patent number 11,512,325
- Issue date Nov 29, 2022
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Use and production of CHD8+/− transgenic animals with behavioral ph...
- Patent number 11,459,557
- Issue date Oct 4, 2022
- The Broad Institute, Inc.
- Randall Jeffrey Platt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Molecular cell diary system
- Patent number 11,447,768
- Issue date Sep 20, 2022
- University of Florida Research Foundation, Incorporated
- David Tran
- G01 - MEASURING TESTING
Information Patent Grant
Cancer treatment through RLIP76 partial depletion
- Patent number 11,427,816
- Issue date Aug 30, 2022
- Board of Regents, The University of Texas System
- Sanjay Awasthi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nuclease-based RNA depletion
- Patent number 11,421,216
- Issue date Aug 23, 2022
- Illumina, Inc.
- Scott Kuersten
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for treating Leber congenital amaurosis
- Patent number 11,421,219
- Issue date Aug 23, 2022
- THE USA, AS REPRESENTED BY THE SECRETARY, DHHS
- Zhijian Wu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for introducing site-directed RNA mutation, target editing g...
- Patent number 11,390,865
- Issue date Jul 19, 2022
- Fukuoka University
- Masatora Fukuda
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
Microinjection system and method
- Publication number 20240417663
- Publication date Dec 19, 2024
- Life Science Methods B.V.
- Jan de Sonneville
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ERROR PRONE DNA POLYMERASE FOR ORGANELLE MUTATION
- Publication number 20240417703
- Publication date Dec 19, 2024
- THE UNIVERSITY OF MANCHESTER
- Junwei Ji
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Split Cas9 Proteins
- Publication number 20240376463
- Publication date Nov 14, 2024
- President and Fellows of Harverd College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T CELL RECEPTOR, AND PREPARATION METHOD AND USE THEREOF
- Publication number 20240358832
- Publication date Oct 31, 2024
- SUZHOU INSTITUTE OF SYSTEMS MEDICINE
- Guideng LI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-Guided Human Genome Engineering
- Publication number 20240294939
- Publication date Sep 5, 2024
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-Guided Human Genome Engineering
- Publication number 20240279677
- Publication date Aug 22, 2024
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION
- Publication number 20240271119
- Publication date Aug 15, 2024
- THE BROAD INSTITUTE, INC.
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Nuclease-Based RNA Depletion
- Publication number 20240263164
- Publication date Aug 8, 2024
- Illumina, Inc.
- Scott Kuersten
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ELECTROPORATION, DEVELOPMENTALLY-ACTIVATED CELLS, PLURIPOTENT-LIKE...
- Publication number 20240228941
- Publication date Jul 11, 2024
- Christopher B. Reid
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
KINASE MUTANTS AND USES THEREOF
- Publication number 20240180965
- Publication date Jun 6, 2024
- SIB Swiss Institute of Bioinformatics
- Olivier Michielin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Method to Screen For a Mutant Within a Population of Organisms By A...
- Publication number 20240182961
- Publication date Jun 6, 2024
- Carlsberg A/S
- Toni Wendt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
METHODS AND SYSTEMS FOR GENERATING NUCLEIC ACID DIVERSITY
- Publication number 20240182886
- Publication date Jun 6, 2024
- INSTITUT PASTEUR
- David BIKARD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPACT PROMOTERS FOR GENE EDITING
- Publication number 20240175006
- Publication date May 30, 2024
- HUNTERIAN MEDICINE LLC
- Vinod Jaskula-Ranga
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MICROORGANISMS AND USES THEREOF
- Publication number 20240158736
- Publication date May 16, 2024
- United Kingdom Research and Innovation
- Wesley E. ROBERTSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED BI-STABLE TOGGLE SWITCH AND USES THEREOF
- Publication number 20240141324
- Publication date May 2, 2024
- Massachusetts Institute of Technology
- Ron Weiss
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MICROORGANISMS AND USES THEREOF
- Publication number 20240117295
- Publication date Apr 11, 2024
- United Kingdom Research and Innovation
- Wesley E. ROBERTSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR PRODUCING RNA MOLECULE COMPOSITIONS
- Publication number 20240100142
- Publication date Mar 28, 2024
- CureVac SE
- Tilmann ROOS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS I...
- Publication number 20240101590
- Publication date Mar 28, 2024
- The Scripps Research Institute
- Floyd E. ROMESBERG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING
- Publication number 20240093241
- Publication date Mar 21, 2024
- The Regents of the University of Colorado, a Body Corporate
- Andrew GARST
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
ADENOSINE NUCLEOBASE EDITORS AND USES THEREOF
- Publication number 20240076652
- Publication date Mar 7, 2024
- President and Fellows of Harvard College
- David R. LIU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR THE TARGETED MODIFICATION OF A GENOME
- Publication number 20240052365
- Publication date Feb 15, 2024
- Regeneron Pharmaceuticals, Inc.
- David Frendewey
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-GUIDED ENDONUCLEASE FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
- Publication number 20230399630
- Publication date Dec 14, 2023
- The Regents of the University of California
- Schaked Omer Halperin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-GUIDED ENDONUCLEASE FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
- Publication number 20230399631
- Publication date Dec 14, 2023
- The Regents of the University of California
- Schaked Omer Halperin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Platform for developing stable mammalian cell lines
- Publication number 20230340542
- Publication date Oct 26, 2023
- Icosagen Cell Factory OÜ
- Kadri ÕUNAP
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-Guided Human Genome Engineering
- Publication number 20230295653
- Publication date Sep 21, 2023
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
A HIGHLY ERROR-PRONE ORTHOGONAL DNA REPLICATION SYSTEM FOR TARGETED...
- Publication number 20230242902
- Publication date Aug 3, 2023
- The Regents of the University of California
- Chang C. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SINGLE-STRANDED OLIGONUCLEOTIDE
- Publication number 20230183702
- Publication date Jun 15, 2023
- NISSAN CHEMICAL CORPORATION
- Yusuke IRIYAMA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
RNA STABILIZATION
- Publication number 20230101362
- Publication date Mar 30, 2023
- Team Medical LLC
- Kyle P. Heim
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TARGETING TRANSFER RNA FOR THE SUPPRESSION OF NONSENSE MUTATIONS IN...
- Publication number 20230053353
- Publication date Feb 23, 2023
- The Regents of the University of California
- Prashant Mali
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR THE TREATMENT OF EPILEPSY
- Publication number 20230039652
- Publication date Feb 9, 2023
- Inserm (institut National de la Sante et de la Recherche Medicale)
- Valérie CREPEL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Yeast with improved alcohol production under high dissolved solids...

RNA-guided human genome engineering

Methods and products for expressing proteins in cells

Adenosine nucleobase editors and uses thereof

Nuclease-based RNA depletion

Adenine DNA base editor variants with reduced off-target RNA editing

Method to screen for a mutant within a population of organisms by a...

Electroporation, developmentally-activated cells, pluripotent-like...

Methods and compositions for the targeted modification of a genome

CRISPR enabled multiplexed genome engineering

Repairing compound heterozygous recessive mutations by allele exchange

Kinase mutants and uses thereof

Genomic sequence modification method for specifically converting nu...

CRISPR enabled multiplexed genome engineering

Adenosine nucleobase editors and uses thereof

Method for producing RNA molecule compositions

Platform for developing stable mammalian cell lines

RNA-guided endonuclease fusion polypeptides and methods of use thereof

RNA-guided endonuclease fusion polypeptides and methods of use thereof

CRISPR enabled multiplexed genome engineering

Method for the site-specific enzymatic labelling of nucleic acids i...

Single-stranded oligonucleotide

RNA-guided human genome engineering

RNA-guided human genome engineering

Use and production of CHD8+/− transgenic animals with behavioral ph...

Molecular cell diary system

Cancer treatment through RLIP76 partial depletion

Nuclease-based RNA depletion

Methods and compositions for treating Leber congenital amaurosis

Method for introducing site-directed RNA mutation, target editing g...

Patents Applicationslast 30 patents

Microinjection system and method

ERROR PRONE DNA POLYMERASE FOR ORGANELLE MUTATION

Split Cas9 Proteins

T CELL RECEPTOR, AND PREPARATION METHOD AND USE THEREOF

RNA-Guided Human Genome Engineering

RNA-Guided Human Genome Engineering

METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION

Nuclease-Based RNA Depletion

ELECTROPORATION, DEVELOPMENTALLY-ACTIVATED CELLS, PLURIPOTENT-LIKE...

KINASE MUTANTS AND USES THEREOF

Method to Screen For a Mutant Within a Population of Organisms By A...

METHODS AND SYSTEMS FOR GENERATING NUCLEIC ACID DIVERSITY

COMPACT PROMOTERS FOR GENE EDITING

MICROORGANISMS AND USES THEREOF

ENGINEERED BI-STABLE TOGGLE SWITCH AND USES THEREOF

MICROORGANISMS AND USES THEREOF

METHOD FOR PRODUCING RNA MOLECULE COMPOSITIONS

METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS I...

CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING

ADENOSINE NUCLEOBASE EDITORS AND USES THEREOF

METHODS AND COMPOSITIONS FOR THE TARGETED MODIFICATION OF A GENOME

RNA-GUIDED ENDONUCLEASE FUSION POLYPEPTIDES AND METHODS OF USE THEREOF

RNA-GUIDED ENDONUCLEASE FUSION POLYPEPTIDES AND METHODS OF USE THEREOF

Platform for developing stable mammalian cell lines

RNA-Guided Human Genome Engineering

A HIGHLY ERROR-PRONE ORTHOGONAL DNA REPLICATION SYSTEM FOR TARGETED...

SINGLE-STRANDED OLIGONUCLEOTIDE

RNA STABILIZATION

TARGETING TRANSFER RNA FOR THE SUPPRESSION OF NONSENSE MUTATIONS IN...

METHODS FOR THE TREATMENT OF EPILEPSY