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Introduction of foreign genetic material using vectors Vectors Use of hosts therefor Regulation of expression
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C12N15/63
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
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C12N15/63
Introduction of foreign genetic material using vectors Vectors Use of hosts therefor Regulation of expression
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Patents Grants
last 30 patents
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Patent Grant
Polypeptide containing DNA-binding domain
Patent number
12,359,180
Issue date
Jul 15, 2025
Hiroshima University
Takashi Yamamoto
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
High-efficacy crispri system and strong synthetic promoters for alp...
Patent number
12,359,198
Issue date
Jul 15, 2025
Wisconsin Alumni Research Foundation
Jason Peters
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Thermal control of T-cell immunotherapy through molecular and physi...
Patent number
12,359,208
Issue date
Jul 15, 2025
California Institute of Technology
Mohamad H. Abedi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Polypeptide variants
Patent number
12,359,182
Issue date
Jul 15, 2025
Novozymes A/S
Roland Alexander Pache
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information
Patent Grant
Proteolytically cleavable chimeric polypeptides and methods of use...
Patent number
12,358,988
Issue date
Jul 15, 2025
The Regents of the University of California
Wendell A. Lim
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Anti-8-hydroxy-2′-deoxyguanosine antibody or antibody fragment ther...
Patent number
12,359,000
Issue date
Jul 15, 2025
TDK Corporation
Takeshi Sakamoto
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CPF1 protein and its use in gene editing
Patent number
12,351,840
Issue date
Jul 8, 2025
HANGZHOU LUCA INTELLIGENT TECHNOLOGY CO., LTD.
Jin Tang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method to produce conditionally apoptotic cells
Patent number
12,351,826
Issue date
Jul 8, 2025
RIGENERAND S.R.L.
Filippo Rossignoli
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chimeric antigen receptors targeting BCMA and methods of use thereof
Patent number
12,351,638
Issue date
Jul 8, 2025
Legend Biotech USA Inc.
Xiaohu Fan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Polypeptides and uses thereof
Patent number
12,351,603
Issue date
Jul 8, 2025
Shanxi Jinbo Bio-Pharmaceutical Co., Ltd
Xia Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Serum albumin-binding fibronectin type III domains and uses thereof
Patent number
12,351,619
Issue date
Jul 8, 2025
ARO BIOTHERAPEUTICS COMPANY
Karyn O'Neil
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CPF1 complexes with reduced indel activity
Patent number
12,344,838
Issue date
Jul 1, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered Pyrococcus enzymes and uses thereof
Patent number
12,344,867
Issue date
Jul 1, 2025
Singular Genomics Systems, Inc.
Souad Naji
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Clostridioides difficile TcdB variants, vaccines and methods of use
Patent number
12,343,388
Issue date
Jul 1, 2025
The Board of Regents of the University of Oklahoma
Jimmy D. Ballard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Anti-Notch3 antibody
Patent number
12,338,282
Issue date
Jun 24, 2025
AVEO PHARMACEUTICALS, INC.
Heidi Okamura
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for making high intensity sweeteners
Patent number
12,338,476
Issue date
Jun 24, 2025
Firmenich Incorporated
Andrew P. Patron
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Photoactivatable Tet expression control system
Patent number
12,338,443
Issue date
Jun 24, 2025
Japan Science and Technology Agency
Itaru Imayoshi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DDR1 antibodies and uses thereof
Patent number
12,331,130
Issue date
Jun 17, 2025
The Board of Regents of the University of Texas System
Ningyan Zhang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Recombinant herpes simplex virus for cancer immunotherapy
Patent number
12,329,794
Issue date
Jun 17, 2025
The Board of Trustees of the University of Illinois
Bin He
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RNA-guided DNA integration using Tn7-like transposons
Patent number
12,331,292
Issue date
Jun 17, 2025
The Trustees of Columbia University In the City of New York
Samuel Henry Sternberg
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Anti-human NR1 antibody derivative
Patent number
12,331,113
Issue date
Jun 17, 2025
ARIALYS THERAPEUTICS, INC.
Satoshi Kubo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Fusion polypeptides for metabolic disorders
Patent number
12,331,093
Issue date
Jun 17, 2025
BEIJING QL BIOPHARMACEUTICAL CO., LT
Yuanyuan Zhang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Genome edited cancer cell vaccines
Patent number
12,331,320
Issue date
Jun 17, 2025
The Research Foundation for the State University of New York
Kaiming Ye
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nucleic acid vaccine against the SARS-CoV-2 coronavirus
Patent number
12,324,834
Issue date
Jun 10, 2025
Institut Pasteur
Etienne Simon-Loriere
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Gene editing using homology-independent universal genome engineerin...
Patent number
12,325,855
Issue date
Jun 10, 2025
Duke University
Yudong Gao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified fibroin
Patent number
12,319,718
Issue date
Jun 3, 2025
SPIBER INC.
Keisuke Morita
D01 - NATURAL OR ARTIFICIAL THREADS OR FIBRES SPINNING
Information
Patent Grant
Chimeric protein, method of production and use thereof, and also a...
Patent number
12,320,807
Issue date
Jun 3, 2025
Fundação Oswaldo Cruz
Osvaldo Pompílio de Melo Neto
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
IL-2 mutant and application thereof
Patent number
12,319,725
Issue date
Jun 3, 2025
HAINAN SIMCERE PHARMACEUTICAL CO., LTD.
Yingying Hu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Human monoclonal antibody binding specifically to human HMGB1, and...
Patent number
12,319,731
Issue date
Jun 3, 2025
INSTITUTE OF SCIENCE TOKYO
Hitoshi Okazawa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antibody or chimeric antigen receptor which targets Claudin 18.2
Patent number
12,312,402
Issue date
May 27, 2025
Shandong Boan Biotechnology Co., Ltd.
Deyong Song
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYM...
Publication number
20250236856
Publication date
Jul 24, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR THE MAKING AND USING OF GUIDE NUCLEIC...
Publication number
20250230432
Publication date
Jul 17, 2025
JumpCode Genomics, Inc.
Stephane B. GOURGUECHON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Mutant Taq Polymerase for Fast Speed Amplification
Publication number
20250223574
Publication date
Jul 10, 2025
AbClonal Science, Inc.
Zhenyu Zhu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CD19 BINDING MOLECULES AND USES THEREOF
Publication number
20250223359
Publication date
Jul 10, 2025
Novartis AG
Brian Granda
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BISPECIFIC ANTI-CD28 X ANTI-CD22 ANTIBODIES AND USES THEREOF
Publication number
20250223360
Publication date
Jul 10, 2025
Regeneron Pharmaceuticals, Inc.
Andrew J. Murphy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAi Agents for Inhibiting Expression of Complement Factor B (CFB),...
Publication number
20250215433
Publication date
Jul 3, 2025
Arrowhead Pharmaceuticals, Inc.
Xiaokai Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETIC TARGETING OF CELLULAR OR NEURONAL SUB-POPULATIONS
Publication number
20250215455
Publication date
Jul 3, 2025
Board of Regents, The University of Texas System
Boris V. ZEMELMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Materials and Methods for Treatment of Hemoglobinopathies
Publication number
20250215427
Publication date
Jul 3, 2025
VERTEX PHARMACEUTICALS INCORPORATED
Matthew Hebden Porteus
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED ACETATE KINASE VARIANT ENZYMES
Publication number
20250215404
Publication date
Jul 3, 2025
Codexis, Inc.
Jonathan Vroom
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF TREATING OR PREVENTING PYRUVATE KINASE DEFICIENCY
Publication number
20250215454
Publication date
Jul 3, 2025
Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, O.A,...
Jose C. SEGOVIA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Anti-NGF Antibodies and Methods Thereof
Publication number
20250206831
Publication date
Jun 26, 2025
Zoetis Services LLC
Sebastian C. J. Steiniger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYNTHETIC GENE CLUSTERS
Publication number
20250207141
Publication date
Jun 26, 2025
The Regents of the University of California
Ethan Mirsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR EXPRESSING SYNTHETIC GENETIC ELEMENTS...
Publication number
20250207124
Publication date
Jun 26, 2025
Yale University
Farren Isaacs
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Anti-NGF Antibodies and Methods Thereof
Publication number
20250206832
Publication date
Jun 26, 2025
Zoetis Services LLC
Sebastian C. J. Steiniger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GLYCOENGINEERED Fc VARIANT POLYPEPTIDES WITH ENHANCED EFFECTOR FUNC...
Publication number
20250206824
Publication date
Jun 26, 2025
Ablynx N.V.
Julie A. Jaworski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENE AUGMENTATION THERAPIES FOR INHERITED RETINAL DEGENERATION CAUS...
Publication number
20250195691
Publication date
Jun 19, 2025
Massachusetts Eye and Ear Infirmary
Eric A. Pierce
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Multiplexed Analysis of Materials for Tissue Delivery
Publication number
20250195688
Publication date
Jun 19, 2025
Georgia Tech Research Corporation
James Dahlman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GLUCAGON LIKE PEPTIDE 1 (GLP1)-GROWTH DIFFERENTIATION FACTOR 15 (GD...
Publication number
20250197468
Publication date
Jun 19, 2025
Janssen Sciences Ireland Unlimited Company
Shannon MULLICAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SIRP ALPHA, SIRP BETA 1, AND SIRP GAMMA ANTIBODIES AND USES THEREOF
Publication number
20250197492
Publication date
Jun 19, 2025
Electra Therapeutics, Inc.
Sandip PANICKER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND BCMA VARIANT...
Publication number
20250197528
Publication date
Jun 19, 2025
SANOFI
Nicolas GOURDIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED BACTERIAL RETROELEMENT WITH ENHANCED DNA PRODUCTION
Publication number
20250188442
Publication date
Jun 12, 2025
THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE...
Seth Shipman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RECOMBINOGENIC NUCLEIC ACID STRANDS IN SITU
Publication number
20250186625
Publication date
Jun 12, 2025
SNIPR Technologies Limited
Jasper CLUBE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR TARGETED GENE TRANSFER
Publication number
20250186478
Publication date
Jun 12, 2025
The University of North Carolina at Chapel Hill
Kenton Woodard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS RELATED TO IL27 RECEPTOR BINDING
Publication number
20250179198
Publication date
Jun 5, 2025
Synthekine, Inc.
Robert Kastelein
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACIDS ENCODING SWITCH RECEPTORS USING IL-9 RECEPTOR SIGNALI...
Publication number
20250179148
Publication date
Jun 5, 2025
Parker Institute for Cancer Immunotherapy
John CONNOLLY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TARGETED THERAPEUTIC DELIVERY TO BONE
Publication number
20250179136
Publication date
Jun 5, 2025
Theradaptive, Inc.
Luis ALVAREZ
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MICROORGANISM STRAIN FOR ANTIBIOTIC-FREE PLASMID-BASED FERMENTATION...
Publication number
20250179506
Publication date
Jun 5, 2025
Gen-H Genetic Engineering Heidelberg GmbH
Harald KRANZ
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
ENGINEERED MICROORGANISMS AND METHODS OF MAKING AND USING SAME
Publication number
20250179424
Publication date
Jun 5, 2025
Washington University
Gautam DANTAS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Materials and Methods for Treatment of Hemoglobinopathies
Publication number
20250171800
Publication date
May 29, 2025
VERTEX PHARMACEUTICALS INCORPORATED
Matthew Hebden PORTEUS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IL27RAlpha BINDING MOLECULES AND METHODS OF USE
Publication number
20250171548
Publication date
May 29, 2025
Synthekine, Inc.
Robert Kastelein
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...