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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
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C12N2310/352
linked to the nucleic acid via a carbon atom
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Patents Grants
last 30 patents
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Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Bi specific aptamer
Patent number
12,138,279
Issue date
Nov 12, 2024
City of Hope
John J. Rossi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Base editing of ANGPTL3 and methods of using same for treatment of...
Patent number
12,115,230
Issue date
Oct 15, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
GLP-1 receptor ligand moiety conjugated oligonucleotides and uses t...
Patent number
12,115,225
Issue date
Oct 15, 2024
Astrazeneca AB
Brett P. Monia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted inhibition using engineered oligonucleotides
Patent number
12,104,157
Issue date
Oct 1, 2024
MIRECULE, INC.
Robert Place
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Insulin receptor aptamer and pharmaceutical composition for treatin...
Patent number
12,060,560
Issue date
Aug 13, 2024
APTAMER SCIENCES INC.
Youndong Kim
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for targeting RNA polymerases and non-codi...
Patent number
12,043,839
Issue date
Jul 23, 2024
The Regents of the University of California
Steve E. Jacobsen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Base editing of PCSK9 and methods of using same for treatment of di...
Patent number
12,029,795
Issue date
Jul 9, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Single-stranded RNA-editing oligonucleotides
Patent number
12,018,257
Issue date
Jun 25, 2024
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA interference mediated inhibition of prolyl hydroxylase domain 2...
Patent number
11,952,573
Issue date
Apr 9, 2024
SIRNA Therapeutics, Inc.
Brandon Ason
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Reducing intron retention
Patent number
11,891,605
Issue date
Feb 6, 2024
University of Southampton
Igor Vorechovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Complement component C5 iRNA compositions and methods of use thereof
Patent number
11,873,491
Issue date
Jan 16, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing LRRK2 expression
Patent number
11,873,495
Issue date
Jan 16, 2024
Ionis Pharmaceuticals, Inc.
Tracy A. Cole
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Glucokinase (GCK) iRNA compositions and methods of use thereof
Patent number
11,859,185
Issue date
Jan 2, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotide compositions
Patent number
11,859,180
Issue date
Jan 2, 2024
Ionis Pharmaceuticals, Inc.
Andrew Dibble
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
Patent number
11,851,655
Issue date
Dec 26, 2023
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified nucleic acids, hybrid guide RNAs, and uses thereof
Patent number
11,845,929
Issue date
Dec 19, 2023
OHIO STATE INNOVATION FOUNDATION
Yizhou Dong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Allele selective inhibition of mutant C9orf72 foci expression by du...
Patent number
11,840,690
Issue date
Dec 12, 2023
The Board of Regents of the University of Texas System
David Corey
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulation of prekallikrein (PKK) expression
Patent number
11,840,686
Issue date
Dec 12, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for treating transthyretin (TTR) mediated...
Patent number
11,806,360
Issue date
Nov 7, 2023
Alnylam Pharmaceuticals, Inc.
Jared Gollob
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted inhibition using engineered oligonucleotides
Patent number
11,795,459
Issue date
Oct 24, 2023
MIRECULE, INC.
Robert Place
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Defined multi-conjugates oligonucleotides
Patent number
11,767,531
Issue date
Sep 26, 2023
MPEG LA, LLC
Philipp Hadwiger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
SiRNA, medical compositions, and methods for treating type ii diabe...
Patent number
11,746,350
Issue date
Sep 5, 2023
Peking University
Liangyi Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for performing antisense oligonucleotide-mediated exon skip...
Patent number
11,667,913
Issue date
Jun 6, 2023
Inserm
Jean-Michel Rozet
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of antithrombi...
Patent number
11,667,918
Issue date
Jun 6, 2023
Dicerna Pharmaceuticals, Inc.
Bob D. Brown
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Single-stranded RNA-editing oligonucleotides
Patent number
11,649,454
Issue date
May 16, 2023
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating apolipoprotein (a) expression
Patent number
11,634,711
Issue date
Apr 25, 2023
Ionis Pharmaceuticals, Inc.
Rosanne M. Crooke
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligonucleotide compositions and methods of use thereof
Patent number
11,597,927
Issue date
Mar 7, 2023
WAVE LIFE SCIENCES LTD.
Chandra Vargeese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing ATXN3 expression
Patent number
11,583,548
Issue date
Feb 21, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Interfering RNA molecules
Patent number
11,578,328
Issue date
Feb 14, 2023
Silence Therapeutics GmbH
Klaus Giese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
Publication number
20250034566
Publication date
Jan 30, 2025
Alnylam Pharmaceuticals, Inc.
Brian Bettencourt
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LACTATE DEHYDROGENASE A (LDHA) iRNA COMPOSITIONS AND METHODS OF USE...
Publication number
20250017953
Publication date
Jan 16, 2025
Alnylam Pharmaceuticals, Inc.
David Erbe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA MODULATING OLIGONUCLEOTIDES WITH IMPROVED CHARACTERISTICS FOR T...
Publication number
20250011784
Publication date
Jan 9, 2025
VICO Therapeutics B.V.
Peter Christian DE VISSER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES
Publication number
20240417721
Publication date
Dec 19, 2024
ProQR Therapeutics II B.V.
Janne Juha TURUNEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRES...
Publication number
20240401038
Publication date
Dec 5, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...
Publication number
20240390523
Publication date
Nov 28, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DYSTROPHIN EXON SKIPPING OLIGONUCLEOTIDES
Publication number
20240368596
Publication date
Nov 7, 2024
BioMarin Pharmaceutical Inc.
Thomas Aaron Hartl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compounds and Methods for Reducing LRRK2 Expression
Publication number
20240360453
Publication date
Oct 31, 2024
Ionis Pharmaceuticals, Inc.
Tracy A. Cole
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE INHIBITORS OF MIR17HG PRE-RNA AS THERAPEUTIC AGENTS IN CA...
Publication number
20240352462
Publication date
Oct 24, 2024
Dana-Farber Cancer Institute, Inc.
Nikhil C. Munshi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION
Publication number
20240352455
Publication date
Oct 24, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT FOR TYROSINE DEGRADATION-ASSOCIATED DISORDERS
Publication number
20240344072
Publication date
Oct 17, 2024
UCL Business LTD
Haiyan Zhou
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES T...
Publication number
20240336924
Publication date
Oct 10, 2024
CAMP4 THERAPEUTICS CORPORATION
Alfica Sehgal
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ALLELE-SELECTIVE COMPOUNDS AND METHODS FOR MODULATING HUNTINGTIN EX...
Publication number
20240325425
Publication date
Oct 3, 2024
Ionis Pharmaceuticals, Inc.
Michael OESTERGAARD
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NOVEL THERAPEUTIC DELIVERY MOIETIES AND USES THEREOF
Publication number
20240327839
Publication date
Oct 3, 2024
Eli Lilly and Company
Patrick Joseph ANTONELLIS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-BASED COMPOSITIONS AND METHODS OF USE
Publication number
20240318171
Publication date
Sep 26, 2024
Integrated DNA Technologies, Inc.
Michael Allen Collingwood
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDE TARGETING ATN1 MRNA OR PRE-MRNA
Publication number
20240318181
Publication date
Sep 26, 2024
NIPPON SHINYAKU CO., LTD.
Takao KAWANO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATION OF PREKALLIKREIN (PKK) EXPRESSION
Publication number
20240318183
Publication date
Sep 26, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240309387
Publication date
Sep 19, 2024
Alnylam Pharmaceuticals, Inc.
James Butler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
REDUCING INTRON RETENTION
Publication number
20240309377
Publication date
Sep 19, 2024
UNIVERSITY OF SOUTHAMPTON
Igor Vorechovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLE...
Publication number
20240309372
Publication date
Sep 19, 2024
University of Massachusetts
Ken Yamada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA Compositions and Methods for Silencing Filamin A (FLNA)
Publication number
20240301418
Publication date
Sep 12, 2024
Alnylam Pharmaceuticals, Inc.
KIRK BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR CORRECTING LIMB GIRDLE MUSCULAR DYSTRO...
Publication number
20240301428
Publication date
Sep 12, 2024
The University of Chicago
Elizabeth McNally
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR REDUCING TAU EXPRESSION
Publication number
20240301422
Publication date
Sep 12, 2024
Biogen MA Inc.
Holly Kordasiewicz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GLUCOKINASE (GCK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240287524
Publication date
Aug 29, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LIGAND-BINDING NUCLEIC ACID COMPLEX
Publication number
20240279655
Publication date
Aug 22, 2024
RENA THERAPEUTICS INC.
Koh TAKAGI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240271136
Publication date
Aug 15, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SERPINA1 SIRNAS: COMPOSITIONS OF MATTER AND METHODS OF TREATMENT
Publication number
20240255880
Publication date
Aug 1, 2024
Alnylam Pharmaceuticals, Inc.
Alfica Sehgal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
Publication number
20240254486
Publication date
Aug 1, 2024
Alnylam Pharmaceuticals, Inc.
Brian Bettencourt
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE
Publication number
20240247260
Publication date
Jul 25, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATE...
Publication number
20240247271
Publication date
Jul 25, 2024
SIRNA THERAPEUTICS, INC.
Duncan Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...