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linked to the nucleic acid via a carbon atom
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C12N2310/352
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Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N2310/00
Structure or type of the nucleic acid
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C12N2310/352
linked to the nucleic acid via a carbon atom
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Patents Grants
last 30 patents
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Patent Grant
RNA interference mediated inhibition of prolyl hydroxylase domain 2...
Patent number
11,952,573
Issue date
Apr 9, 2024
SIRNA Therapeutics, Inc.
Brandon Ason
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Reducing intron retention
Patent number
11,891,605
Issue date
Feb 6, 2024
University of Southampton
Igor Vorechovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Complement component C5 iRNA compositions and methods of use thereof
Patent number
11,873,491
Issue date
Jan 16, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing LRRK2 expression
Patent number
11,873,495
Issue date
Jan 16, 2024
Ionis Pharmaceuticals, Inc.
Tracy A. Cole
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Glucokinase (GCK) iRNA compositions and methods of use thereof
Patent number
11,859,185
Issue date
Jan 2, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotide compositions
Patent number
11,859,180
Issue date
Jan 2, 2024
Ionis Pharmaceuticals, Inc.
Andrew Dibble
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
Patent number
11,851,655
Issue date
Dec 26, 2023
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified nucleic acids, hybrid guide RNAs, and uses thereof
Patent number
11,845,929
Issue date
Dec 19, 2023
OHIO STATE INNOVATION FOUNDATION
Yizhou Dong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Allele selective inhibition of mutant C9orf72 foci expression by du...
Patent number
11,840,690
Issue date
Dec 12, 2023
The Board of Regents of the University of Texas System
David Corey
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulation of prekallikrein (PKK) expression
Patent number
11,840,686
Issue date
Dec 12, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for treating transthyretin (TTR) mediated...
Patent number
11,806,360
Issue date
Nov 7, 2023
Alnylam Pharmaceuticals, Inc.
Jared Gollob
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted inhibition using engineered oligonucleotides
Patent number
11,795,459
Issue date
Oct 24, 2023
MIRECULE, INC.
Robert Place
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Defined multi-conjugates oligonucleotides
Patent number
11,767,531
Issue date
Sep 26, 2023
MPEG LA, LLC
Philipp Hadwiger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
SiRNA, medical compositions, and methods for treating type ii diabe...
Patent number
11,746,350
Issue date
Sep 5, 2023
Peking University
Liangyi Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for performing antisense oligonucleotide-mediated exon skip...
Patent number
11,667,913
Issue date
Jun 6, 2023
Inserm
Jean-Michel Rozet
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of antithrombi...
Patent number
11,667,918
Issue date
Jun 6, 2023
Dicerna Pharmaceuticals, Inc.
Bob D. Brown
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Single-stranded RNA-editing oligonucleotides
Patent number
11,649,454
Issue date
May 16, 2023
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating apolipoprotein (a) expression
Patent number
11,634,711
Issue date
Apr 25, 2023
Ionis Pharmaceuticals, Inc.
Rosanne M. Crooke
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligonucleotide compositions and methods of use thereof
Patent number
11,597,927
Issue date
Mar 7, 2023
WAVE LIFE SCIENCES LTD.
Chandra Vargeese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing ATXN3 expression
Patent number
11,583,548
Issue date
Feb 21, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Interfering RNA molecules
Patent number
11,578,328
Issue date
Feb 14, 2023
Silence Therapeutics GmbH
Klaus Giese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide therapy for Wilson disease
Patent number
11,578,327
Issue date
Feb 14, 2023
DEEP GENOMICS INCORPORATED
Daniele Merico
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligomeric compounds comprising bicyclic nucleotides and uses thereof
Patent number
11,566,245
Issue date
Jan 31, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of FOXP3 expression
Patent number
11,547,718
Issue date
Jan 10, 2023
Ionis Pharmaceuticals, Inc.
Alexey Revenko
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of reducing expression of x-inactivation escapee genes and...
Patent number
11,401,518
Issue date
Aug 2, 2022
The General Hospital Corporation
Jeannie T. Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Neutral nanotransporters
Patent number
11,396,654
Issue date
Jul 26, 2022
Phio Pharmaceuticals Corp.
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Reducing intron retention
Patent number
11,390,869
Issue date
Jul 19, 2022
University of Southampton
Igor Vorechovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotide-based progranulin augmentation therapy in...
Patent number
11,359,199
Issue date
Jun 14, 2022
President and Fellows of Harvard College
Peter Jungsoo Park
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Defined multi-conjugate oligonucleotides
Patent number
11,352,629
Issue date
Jun 7, 2022
MPEG LA, LLC
Philipp Hadwiger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA modulating oligonucleotides with improved characteristics for t...
Patent number
11,345,915
Issue date
May 31, 2022
VICO THERAPEUTICS B.V.
Peter Christian De Visser
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
TARGETED INHIBITION USING ENGINEERED OLIGONUCLEOTIDES
Publication number
20240141346
Publication date
May 2, 2024
miRecule, Inc.
Robert PLACE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ALLELE SELECTIVE INHIBITION OF MUTANT C9ORF72 FOCI EXPRESSION BY DU...
Publication number
20240141348
Publication date
May 2, 2024
The Board of Regents of the University of Texas System
David COREY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR PERFORMING ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIP...
Publication number
20240117344
Publication date
Apr 11, 2024
Inserm (institut National de la Sante et de la Recherche Medicale)
Jean-Michel ROZET
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING MYOTONIC D...
Publication number
20240117356
Publication date
Apr 11, 2024
Dyne Therapeutics, Inc.
Romesh R. Subramanian
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF APOLIPOPRO...
Publication number
20240110180
Publication date
Apr 4, 2024
Alnylam Pharmaceuticals, Inc.
Brian Bettencourt
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES USING TR...
Publication number
20240100080
Publication date
Mar 28, 2024
Alnylam Pharmaceuticals, Inc.
Amy Chan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR REDUCING ATXN3 EXPRESSION
Publication number
20240082291
Publication date
Mar 14, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING TRANSTHYRETIN (TTR) MEDIATED...
Publication number
20240075052
Publication date
Mar 7, 2024
Alnylam Pharmaceuticals, Inc.
Jared A. Gollob
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING APOLIPOPROTEIN (A) EXPRESSION
Publication number
20240067964
Publication date
Feb 29, 2024
Ionis Pharmaceuticals, Inc.
Rosanne M. Crooke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR MODULATING TMPRSS6 EXPRESSION
Publication number
20240026364
Publication date
Jan 25, 2024
Ionis Pharmaceuticals, Inc.
Shuling Guo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SIRNA, MEDICAL COMPOSITIONS, AND METHODS FOR TREATING DIABETES USIN...
Publication number
20230383299
Publication date
Nov 30, 2023
Peking University
Liangyi CHEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR MODULATING PMP22
Publication number
20230374519
Publication date
Nov 23, 2023
Ionis Pharmaceuticals, Inc.
Eric E. Swayze
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING SCAP ACTIVITY
Publication number
20230374522
Publication date
Nov 23, 2023
Dicerna Pharmaceuticals, Inc.
Bob Dale BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20230365965
Publication date
Nov 16, 2023
Genzyme Corporation
Akin Akinc
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Targeted Inhibition Using Engineered Oligonucleotides
Publication number
20230295626
Publication date
Sep 21, 2023
miRecule, Inc.
Robert PLACE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES
Publication number
20230279392
Publication date
Sep 7, 2023
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof
Publication number
20230279396
Publication date
Sep 7, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR TREATING AND PROGNOSING CANCER LIKE GLIOBLASTOMA
Publication number
20230250426
Publication date
Aug 10, 2023
Inserm (institut National de la Sante et de la Recherche Medicale)
Pierre-François CARTRON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MODULATORS OF FOXP3 EXPRESSION
Publication number
20230201243
Publication date
Jun 29, 2023
Ionis Pharmaceuticals, Inc.
Alexey M. REVENKO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
REDUCING INTRON RETENTION
Publication number
20230183693
Publication date
Jun 15, 2023
UNIVERSITY OF SOUTHAMPTON
Igor Vorechovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Modulation of Dystrophia Myotonica-Protein Kinase (DMPK) Expression
Publication number
20230174987
Publication date
Jun 8, 2023
Ionis Pharmaceuticals, Inc.
C. Frank Bennett
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR CORRECTING LIMB GIRDLE MUSCULAR DYSTRO...
Publication number
20230167452
Publication date
Jun 1, 2023
The University of Chicago
Elizabeth McNally
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR SILENCING SCN9A EXPRESSION
Publication number
20230159933
Publication date
May 25, 2023
Alnylam Pharmaceuticals, Inc.
WILLIAM CANTLEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INSULIN RECEPTOR APTAMER AND PHARMACEUTICAL COMPOSITION FOR TREATIN...
Publication number
20230159934
Publication date
May 25, 2023
APTAMER SCIENCES INC.
Youndong Kim
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...
Publication number
20230159926
Publication date
May 25, 2023
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE NUCLEIC ACIDS
Publication number
20230151050
Publication date
May 18, 2023
NIPPON SHINYAKU CO., LTD.
Naoki Watanabe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION
Publication number
20230151365
Publication date
May 18, 2023
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DESIGN METHOD FOR OPTIMIZED RIG-I LIGANDS
Publication number
20230147979
Publication date
May 11, 2023
Rigontec GMBH
Christine Schuberth-Wagner
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Targeted Inhibition Using Engineered Oligonucleotides
Publication number
20230132602
Publication date
May 4, 2023
miRecule, Inc.
Robert PLACE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof
Publication number
20230121967
Publication date
Apr 20, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...