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Non-coding nucleic acids modulating the expression of genes, e.g.antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids
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C12N15/113
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CHEMISTRY METALLURGY
C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
Current Industry
C12N15/113
Non-coding nucleic acids modulating the expression of genes, e.g.antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids
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Patents Grants
last 30 patents
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Patent Grant
Use of IRE1α-XBP1 signaling pathway biomarkers for modulating immun...
Patent number
12,227,548
Issue date
Feb 18, 2025
Dana-Farber Cancer Institute, Inc.
Laurie H. Glimcher
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered cascade components and cascade complexes
Patent number
12,227,776
Issue date
Feb 18, 2025
Caribou Biosciences, Inc.
Peter Sean Cameron
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Molecular programming tools
Patent number
12,227,795
Issue date
Feb 18, 2025
President and Fellows of Harvard College
Jocelyn Yoshiko Kishi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA encoding a therapeutic protein
Patent number
12,227,549
Issue date
Feb 18, 2025
CureVac SE
Mariola Fotin-Mleczek
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds and compositions including phosphorothioated oligodeoxynu...
Patent number
12,227,745
Issue date
Feb 18, 2025
City of Hope
Marcin Tomasz Kortylewski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating SCN2A
Patent number
12,227,746
Issue date
Feb 18, 2025
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Pharmaceutical composition for treatment of diseases associated wit...
Patent number
12,227,743
Issue date
Feb 18, 2025
Osaka University
Fumihiro Sanada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting expression of transthyretin
Patent number
12,227,744
Issue date
Feb 18, 2025
Alnylam Pharmaceuticals, Inc.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Altering microbial populations and modifying microbiota
Patent number
12,226,430
Issue date
Feb 18, 2025
SNIPR TECHNOLOGIES LIMITED
Jasper Clube
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Modulators of CAS9 polypeptides and methods of use thereof
Patent number
12,227,547
Issue date
Feb 18, 2025
The Regents of the University of California
Jennifer A Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CasY compositions and methods of use
Patent number
12,227,753
Issue date
Feb 18, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multi-targeted single entity conjugates
Patent number
12,221,607
Issue date
Feb 11, 2025
Alnylam Pharmaceuticals, Inc.
Vasant Jadhav
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods to restore paternal UBE3A gene expression...
Patent number
12,221,609
Issue date
Feb 11, 2025
University of Connecticut
Stormy Chamberlain
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNAi agents for inhibiting expression of HIF-2 alpha (EPAS1), compo...
Patent number
12,221,610
Issue date
Feb 11, 2025
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified pluripotent cells
Patent number
12,221,622
Issue date
Feb 11, 2025
The Regents of the University of California
Sonja Schrepfer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for organ-protective expression and modula...
Patent number
12,220,456
Issue date
Feb 11, 2025
Combined Therapeutics, Inc.
Romain Micol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions, systems, and methods for regulation of hepatitis b vi...
Patent number
12,221,608
Issue date
Feb 11, 2025
TUNE THERAPEUTICS, INC.
Brian Cosgrove
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems methods, and compositions for targeted nucleic acid editing
Patent number
12,221,636
Issue date
Feb 11, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methylene-tetrahydrofolate reductase isoform-based biomarker and me...
Patent number
12,220,416
Issue date
Feb 11, 2025
Rush University Medical Center
Tibor A. Rauch
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using nucleosome interacting protein domains to enhance targeted ge...
Patent number
12,221,606
Issue date
Feb 11, 2025
Sigma-Aldrich Co. LLC
Fuqiang Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for expressing factor IX
Patent number
12,214,023
Issue date
Feb 4, 2025
Intellia Therapeutics, Inc.
Jonathan Douglas Finn
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cell-specific expression of modRNA
Patent number
12,215,336
Issue date
Feb 4, 2025
Icahn School of Medicine at Mount Sinai
Lior Zangi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Therapeutic targets for the correction of the human dystrophin gene...
Patent number
12,214,054
Issue date
Feb 4, 2025
Duke University
Charles A. Gersbach
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Treatment of liver disease with mitochondrial glycerol-3-phosphate...
Patent number
12,215,322
Issue date
Feb 4, 2025
REGENERON PHARMACEUTICALS, INC.
Luca Andrea Lotta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for targeted genomic insertion
Patent number
12,215,319
Issue date
Feb 4, 2025
Syngenta Crop Protection AG
Zhongying Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of diacyglycerol acyltransferase 2 (DGAT2)
Patent number
12,215,321
Issue date
Feb 4, 2025
Ionis Pharmaceuticals, Inc.
Eric E. Swayze
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,215,343
Issue date
Feb 4, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Therapeutic applications of CPF1-based genome editing
Patent number
12,214,056
Issue date
Feb 4, 2025
Duke University
Charles A. Gersbach
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Systems and methods for treating hyper-igm syndrome
Patent number
12,214,055
Issue date
Feb 4, 2025
Cecillia Cotta-Ramusino
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Process for using CRISPR to transfect primordial germ cells in avians
Patent number
12,213,466
Issue date
Feb 4, 2025
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Scott Geoffrey Tyack
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
TUNABLE REVERSIR TM COMPOUNDS
Publication number
20250059536
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Ivan ZLATEV
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Chimeric Antigen Receptor-T Cells Targeting HIV-Infected Cells
Publication number
20250057884
Publication date
Feb 20, 2025
Beijing Solobio Genetechnology Co., Ltd.
Weijun ZHU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SGLT-2 TARGETING OLIGONUCLEOTIDES
Publication number
20250059539
Publication date
Feb 20, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NLRP3 oligonucleotide for use in preventing and/or treating an infl...
Publication number
20250059547
Publication date
Feb 20, 2025
Secarna Pharmaceuticals GmbH & Co KG
Marta Lucia DE LOS REYES
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OPA1 ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES
Publication number
20250059535
Publication date
Feb 20, 2025
Stoke Therapeutics, Inc.
Isabel Aznarez
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE
Publication number
20250059537
Publication date
Feb 20, 2025
Oxford University Innovation Limited
Tom BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR TARGETED TRANS-SPLICING
Publication number
20250059543
Publication date
Feb 20, 2025
Amber Bio Inc.
Jacob BORRAJO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING A DISEASE O...
Publication number
20250059242
Publication date
Feb 20, 2025
GUANGZHOU INNO-ENMAI BIOMEDICAL TECHNOLOGY CO., LTD
Yingfang LIU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITION FOR PROMOTING MIGRATION OF ADULT STEM CELLS USING INCRE...
Publication number
20250057983
Publication date
Feb 20, 2025
SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
Nayoung Suh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions And Methods Targeting G12 Signaling For Bronchodilator...
Publication number
20250057836
Publication date
Feb 20, 2025
Rutgers, The State University of New Jersey
Reynold Panettieri
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, PR...
Publication number
20250057870
Publication date
Feb 20, 2025
SUZHOU RIBO LIFE SCIENCE CO., LTD
Zicai LIANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions and Methods for Treatment of Ocular Disease Associated...
Publication number
20250057987
Publication date
Feb 20, 2025
4D MOLECULAR THERAPEUTICS INC.
Christian BURNS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES (ASO) FOR EFFICIENT AND PRECISE RNA EDIT...
Publication number
20250059534
Publication date
Feb 20, 2025
Eberhard-Karls-Universitat Tubingen
Thorsten STAFFORST
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DOUBLE STRANDED RNA TARGETING ANGIOPOIETIN-LIKE 3 (ANGPTL-3) AND ME...
Publication number
20250059540
Publication date
Feb 20, 2025
Sanegene Bio USA Inc.
Chunyang ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SNCA-TARGETING SIRNA COMPOSITIONS FOR TREATING SNCA-ASSOCIATED DISEASE
Publication number
20250059541
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Lan Thi Hoang Dang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR TREATING BLADDER CANCER
Publication number
20250059545
Publication date
Feb 20, 2025
HOSPITAL ESPAÑOL AUXILIO MUTUO DE PUERTO RICO, INC.
Eduardo I. CANTO REPETTI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANALYSIS OF NUCLEIC ACIDS ASSOCIATED WITH SINGLE CELLS USING NUCLEI...
Publication number
20250059576
Publication date
Feb 20, 2025
Bruker Spatial Biology, Inc.
Yann Chong TAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS OF tRNA SILENCING
Publication number
20250059538
Publication date
Feb 20, 2025
Shape Therapeutics Inc.
Sandhya Pande
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELL DEATH-INDUCING DFFA-LIKE EFFECTOR B (CIDEB) IRNA COMPOSITIONS...
Publication number
20250059542
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
JEFFREY ZUBER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES (ASOS) THAT SUPPRESS SARS-COV-2 REPLICATION
Publication number
20250059544
Publication date
Feb 20, 2025
The Children's Medical Center Corporation
Hao Wu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENHANCED PRODUCTION OF SQUALENE IN PLANT SYSTEMS
Publication number
20250059546
Publication date
Feb 20, 2025
The Regents of The University of Colorado A Body Corporate
Brian DEDECKER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Exosomes for treating glioblastoma multiforme and manufacturing met...
Publication number
20250057973
Publication date
Feb 20, 2025
China Medical University
Der-Yang Cho
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Guide RNA That Targets A Mutant Human Guanylate Cyclase 2A Allele
Publication number
20250057988
Publication date
Feb 20, 2025
EmendoBio Inc.
Lior Izhar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MicroRNA-Based Therapy Targeted Against LCP-1 Positive Cancers
Publication number
20250057869
Publication date
Feb 20, 2025
THERAMIR LTD
Marianna Prokopi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051765
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA Compositions and Methods for Silencing MYLIP
Publication number
20250051767
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
LUCAS WARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NON-CODING RNA-MEDIATED NEUROLOGICAL DISEASE TREATMENT
Publication number
20250051768
Publication date
Feb 13, 2025
Shanghai GeneMagic BioSciences Co., Ltd.
Haibo ZHOU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Oligonucleotide for Targeting Progranulin
Publication number
20250051772
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DIRECT PRODUCTION OF SIRNAS IN SACCHAROMYCES BOULARDII AND PACKAGIN...
Publication number
20250051774
Publication date
Feb 13, 2025
Mercury Bio, Inc.
Tatiana Vinogradova-Shah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBIN SUBUNIT BETA E (INHBE) MODULATOR COMPOSITIONS AND METHODS O...
Publication number
20250051779
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Aimee M. Deaton
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...