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Ribonuclease H (3.1.26.4)
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C12Y301/26004
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Biochemistry
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ENZYMES
C12Y301/00
Hydrolases acting on ester bonds (3.1)
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C12Y301/26004
Ribonuclease H (3.1.26.4)
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Patents Grants
last 30 patents
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
12,163,131
Issue date
Dec 10, 2024
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for the modulation of proteins
Patent number
12,030,910
Issue date
Jul 9, 2024
Ionis Pharmaceuticals, Inc.
Stanley T. Crooke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNASE H2 mutants that reduce primer dimers and off-target amplifica...
Patent number
12,024,742
Issue date
Jul 2, 2024
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Synthetic reverse transcriptases and uses thereof
Patent number
11,987,822
Issue date
May 21, 2024
SOLIS BIODYNE OÜ
Olev Kahre
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods for identifying a location of an RNA in a biological sample
Patent number
11,952,627
Issue date
Apr 9, 2024
10X GENOMICS, INC.
Marlon Stoeckius
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for detecting on-target and predicted off-target genome edit...
Patent number
11,926,866
Issue date
Mar 12, 2024
Integrated DNA Technologies, Inc.
Joseph Dobosy
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Polynucleotide based movement, kits and methods related thereto
Patent number
11,884,967
Issue date
Jan 30, 2024
Emory University
Khalid Salaita
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for identifying a location of an RNA in a biological sample
Patent number
11,761,038
Issue date
Sep 19, 2023
10X GENOMICS, INC.
Marlon Stoeckius
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
11,753,640
Issue date
Sep 12, 2023
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compact scaffold of Cas9 in the type II CRISPR system
Patent number
11,685,935
Issue date
Jun 27, 2023
Cellectis
Philippe Duchateau
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
11,279,929
Issue date
Mar 22, 2022
Hoffmann-La Roche, Inc.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Inhibitors of nucleotidyl transferases and uses in herpes and hepat...
Patent number
11,191,754
Issue date
Dec 7, 2021
Saint Louis University
John Edwin Tavis
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
System and method for targeted depletion of nucleic acids
Patent number
11,155,853
Issue date
Oct 26, 2021
Roche Sequencing Solutions, Inc.
Venera Bouriakov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Synthetic reverse transcriptases and uses thereof
Patent number
11,046,940
Issue date
Jun 29, 2021
SOLIS BIODYNE OÜ
Olev Kahre
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNase H mutants in an emulsion
Patent number
10,982,273
Issue date
Apr 20, 2021
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for variant detection
Patent number
10,886,006
Issue date
Jan 5, 2021
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for the modulation of proteins
Patent number
10,822,369
Issue date
Nov 3, 2020
Ionis Pharmaceuticals, Inc.
Stanley T. Crooke
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Polynucleotide based movement, kits and methods related thereto
Patent number
10,738,349
Issue date
Aug 11, 2020
Emory University
Khalid Salaita
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for treating or preventing HBV infection or HBV related dis...
Patent number
10,662,414
Issue date
May 26, 2020
Transgene S.A.
Perrine Martin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
System and method for targeted depletion of nucleic acids
Patent number
10,472,666
Issue date
Nov 12, 2019
Roche Sequencing Solutions, Inc.
Venera Bouriakov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for structural determination of selenium derivatized nuclei...
Patent number
10,441,637
Issue date
Oct 15, 2019
SeNA Research, Inc.
Zhen Huang
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
HBV RNAse H purification and enzyme inhibitors
Patent number
10,329,542
Issue date
Jun 25, 2019
Saint Louis University
John Tavis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RNase H-based assays utilizing modified RNA monomers
Patent number
10,227,641
Issue date
Mar 12, 2019
Integrated DNA Technologies, Inc.
Joseph Alan Walder
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
HBV polymerase mutants
Patent number
10,190,105
Issue date
Jan 29, 2019
Transgene S.A.
Perrine Martin
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Mutant reverse transcriptase
Patent number
9,932,567
Issue date
Apr 3, 2018
New England Biolabs, Inc.
Yan Xu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Sequence-specific engineered ribonuclease H and the method for dete...
Patent number
9,353,358
Issue date
May 31, 2016
MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ
Janusz Marek Bujnicki
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for inhibiting RNase H activity of retroid...
Patent number
7,501,503
Issue date
Mar 10, 2009
McGill University
Masad J. Damha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
RNASE H2 MUTANTS THAT REDUCE PRIMER DIMERS AND OFF-TARGET AMPLIFICA...
Publication number
20240318237
Publication date
Sep 26, 2024
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
Publication number
20240301488
Publication date
Sep 12, 2024
10X Genomics, Inc.
Marlon Stoeckius
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR REDUCING PLN EXPRESSION
Publication number
20240191232
Publication date
Jun 13, 2024
Ionis Pharmaceuticals, Inc.
Adam MULLICK
C07 - ORGANIC CHEMISTRY
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20240026360
Publication date
Jan 25, 2024
HOFFMANN-LA ROCHE INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
Publication number
20230383344
Publication date
Nov 30, 2023
10X Genomics, Inc.
Marlon Stoeckius
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNASE H ASSISTED IN SITU ROLLING CIRCLE AMPLIFICATION
Publication number
20230374573
Publication date
Nov 23, 2023
10X Genomics, Inc.
Yufeng QIAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR REDUCING APOE EXPRESSION
Publication number
20230357770
Publication date
Nov 9, 2023
Ionis Pharmaceuticals, Inc.
Tracy A. Cole
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENZYMATIC OLIGONUCLEOTIDE ASSEMBLY USING HAIRPINS AND ENZYMATIC CLE...
Publication number
20230257789
Publication date
Aug 17, 2023
Microsoft Technology Licensing, LLC
Yuan-Jyue CHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FLUORESCENT CROSS-LINKED RNASE H MUTANT CONJUGATE, MIRNA COMBINATIO...
Publication number
20230242994
Publication date
Aug 3, 2023
SHANGHAI MIRAN BIOTECH CO., LTD.
Yiran WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Methods and Systems Involving Digestible Primers for Improving Sing...
Publication number
20230094303
Publication date
Mar 30, 2023
Mission Bio, Inc.
Dalia Dhingra
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNASE H2 MUTANTS THAT REDUCE PRIMER DIMERS AND OFF-TARGET AMPLIFICA...
Publication number
20220348997
Publication date
Nov 3, 2022
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20220177884
Publication date
Jun 9, 2022
HOFFMANN-LA ROCHE INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR VARIANT DETECTION
Publication number
20210395799
Publication date
Dec 23, 2021
Integrated DNA Technologies, Inc.
Joseph Dobosy
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHETIC REVERSE TRANSCRIPTASES AND USES THEREOF
Publication number
20210388327
Publication date
Dec 16, 2021
Solis Biodyne OÜ
Olev KAHRE
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Compounds and Methods for the Modulation of Proteins
Publication number
20210269472
Publication date
Sep 2, 2021
Ionis Pharmaceuticals, Inc.
Stanley T. Crooke
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR VARIANT DETECTION
Publication number
20210202034
Publication date
Jul 1, 2021
Integrated DNA Technologies
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING GSK3B EXPRESSION
Publication number
20210095275
Publication date
Apr 1, 2021
Roche Innovation Center Copenhagen A/S
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Polynucleotide Based Movement, Kits and Methods Related Thereto
Publication number
20200332350
Publication date
Oct 22, 2020
Emory University
Khalid Salaita
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEM AND METHOD FOR TARGETED DEPLETION OF NUCLEIC ACIDS
Publication number
20200024646
Publication date
Jan 23, 2020
Roche Sequencing Solutions, Inc.
Venera Bouriakov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20200010831
Publication date
Jan 9, 2020
HOFFMANN-LA ROCHE, INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYNTHETIC REVERSE TRANSCRIPTASES AND USES THEREOF
Publication number
20190390179
Publication date
Dec 26, 2019
Olev KAHRE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USES IN HERPES AND HEPAT...
Publication number
20190365731
Publication date
Dec 5, 2019
Saint Louis University
John Edwin TAVIS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS OF DEPLETING OR ISOLATING TARGET RNA FROM A NUCLEIC ACID SA...
Publication number
20190284550
Publication date
Sep 19, 2019
SMOBiO Technology, Inc.
KUAN-LIN LEE
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
METHODS OF DEPLETING OR ISOLATING TARGET RNA FROM A NUCLEIC ACID SA...
Publication number
20190284549
Publication date
Sep 19, 2019
SMOBiO Technology, Inc.
KUAN-LIN LEE
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
System and Method for Targeted Depletion of Nucleic Acids
Publication number
20190284602
Publication date
Sep 19, 2019
Roche Sequencing Solutions, Inc.
Venera Bouriakov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR VARIANT DETECTION
Publication number
20190218611
Publication date
Jul 18, 2019
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR VARIANT DETECTION
Publication number
20190221290
Publication date
Jul 18, 2019
Integrated DNA Technologies, Inc.
Joseph Dobosy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HBV Polymerase Mutants
Publication number
20190144840
Publication date
May 16, 2019
Transgene S.A.
Perrine Martin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
System and Method for Targeted Depletion of Nucleic Acids
Publication number
20180223331
Publication date
Aug 9, 2018
Roche Sequencing Solutions, Inc.
Venera Bouriakov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBITORS OF NUCLEOTIDYL TRANSFERASES AND USE IN HERPES AND HEPATI...
Publication number
20180169083
Publication date
Jun 21, 2018
Saint Louis University
John Edwin TAVIS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE