Vector systems comprising sequences for excision in presence of a recombinase

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CPC
C12N2800/30

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2800/00Nucleic acids vectors

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C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase

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Patents Grantslast 30 patents

Information Patent Grant
Non-human animals having a humanized signal-regulatory protein gene
- Patent number 12,161,097
- Issue date Dec 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Targeted integration of nucleic acids
- Patent number 12,129,480
- Issue date Oct 29, 2024
- Genentech, Inc.
- Chi Kin Domingos Ng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Transgenic animals and methods of use
- Patent number 12,096,753
- Issue date Sep 24, 2024
- Matthias Wabl
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Non-human animals models of retinoschisis
- Patent number 12,082,565
- Issue date Sep 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Susannah Brydges
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Engineered DNA binding proteins
- Patent number 12,083,188
- Issue date Sep 10, 2024
- Encoded Therapeutics, Inc.
- Stephanie Tagliatela
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeted modification of rat genome
- Patent number 12,037,596
- Issue date Jul 16, 2024
- REGENERON PHARMACEUTICALS, INC.
- Jeffrey D. Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,974,553
- Issue date May 7, 2024
- Children's Medical Center Corporation
- Frederick W. Alt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Optogenetic construct for allosteric control of protein activity
- Patent number 11,965,002
- Issue date Apr 23, 2024
- THE BD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Andrei Karginov
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Process for the manipulation of nucleic acids
- Patent number 11,959,092
- Issue date Apr 16, 2024
- GlaxoSmithKline Biologicals SA
- Amirreza Faridmoayer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
ADAM6 mice
- Patent number 11,950,578
- Issue date Apr 9, 2024
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Grant
Means and methods for improved regeneration
- Patent number 11,939,586
- Issue date Mar 26, 2024
- VIB VZW
- Lieven De Veylder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for producing genetically modified animals
- Patent number 11,937,586
- Issue date Mar 26, 2024
- OZGENE HOLDINGS PTY LTD
- Frank Koentgen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Preparation of libraries of protein variants expressed in eukaryoti...
- Patent number 11,926,818
- Issue date Mar 12, 2024
- Iontas Limited
- John McCafferty
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Preparation of libraries of protein variants expressed in eukaryoti...
- Patent number 11,912,984
- Issue date Feb 27, 2024
- Iontas Limited
- John McCafferty
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conditional CRISPR sgRNA expression
- Patent number 11,884,917
- Issue date Jan 30, 2024
- IMBA-Institut fur Molekulare Biotechnologie GmbH
- Ulrich Elling
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lineage reporter synthetic chromosomes and methods of use
- Patent number 11,851,719
- Issue date Dec 26, 2023
- CarryGenes Bioengineering, LLC
- Edward Perkins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of introducing multiple expression constructs into a eukary...
- Patent number 11,840,696
- Issue date Dec 12, 2023
- Novozymes A/S
- Qiming Jin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Recombinant cytomegalovirus vectors as vaccines for tuberculosis
- Patent number 11,834,669
- Issue date Dec 5, 2023
- International AIDS Vaccine Initiative, Inc.
- Thomas G. Evans
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Beta-2 microglobulin-deficient cells
- Patent number 11,813,318
- Issue date Nov 14, 2023
- University of Washington
- David W. Russell
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Mammalian cells for producing adeno-associated viruses
- Patent number 11,781,116
- Issue date Oct 10, 2023
- Lonza Ltd
- Marc Feary
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
High-throughput mouse model for optimizing antibody affinities
- Patent number 11,771,069
- Issue date Oct 3, 2023
- Children's Medical Center Corporation
- Frederick W. Alt
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Cas13b orthologues CRISPR enzymes and systems
- Patent number 11,739,308
- Issue date Aug 29, 2023
- The Broad Institute, Inc.
- David Benjamin Turitz Cox
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeted delivery of glycine receptors to excitable cells
- Patent number 11,725,038
- Issue date Aug 15, 2023
- University of Pittsburgh of the Commonwealth System of Higher Education
- Michael Cascio
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeted gene therapies for pain and other neuro-related disorders
- Patent number 11,713,470
- Issue date Aug 1, 2023
- University of Pittsburgh of the Commonwealth System of Higher Education
- Rebecca Seal
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
- Patent number 11,667,677
- Issue date Jun 6, 2023
- The General Hospital Corporation
- Y. Esther Tak
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeted integration into the PPP1R12C locus
- Patent number 11,649,468
- Issue date May 16, 2023
- Sangamo Therapeutics, Inc.
- Russell DeKeiver
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized light chain mice
- Patent number 11,617,357
- Issue date Apr 4, 2023
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized light chain mice
- Patent number 11,612,151
- Issue date Mar 28, 2023
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Genetically modified T cell receptor mice
- Patent number 11,528,895
- Issue date Dec 20, 2022
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for rapid generation of single and multipl...
- Patent number 11,530,389
- Issue date Dec 20, 2022
- RXCELL INC.
- Xianmin Zeng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
NEURODEGENERATIVE AND AMYOTROPHIC MODEL ANIMAL
- Publication number 20240407344
- Publication date Dec 12, 2024
- TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
- Makoto MURAKAMI
- G01 - MEASURING TESTING
Information Patent Application
ENGINEERED DNA BINDING PROTEINS
- Publication number 20240408242
- Publication date Dec 12, 2024
- Encoded Therapeutics, Inc.
- Stephanie TAGLIATELA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-MEIOTIC ALLELE INTROGRESSION
- Publication number 20240397918
- Publication date Dec 5, 2024
- Recombinetics, Inc.
- Scott C. Fahrenkrug
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MAMMALIAN ARTIFICIAL CHROMOSOME VECTOR HAVING HUMAN IMMUNOGLOBULIN...
- Publication number 20240392313
- Publication date Nov 28, 2024
- NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY
- Yasuhiro KAZUKI
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
Genetically Engineered Eukaryotic Cells and Cell Lines and Uses The...
- Publication number 20240368631
- Publication date Nov 7, 2024
- THE TEXAS A&M UNIVERSITY SYSTEM
- Andrew E. Syvyk
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Novel Animal Model for Autoimmune Disease
- Publication number 20240349706
- Publication date Oct 24, 2024
- Industry-Academic Cooperation Foundation, Yonsei University
- Eun Jig Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE PRODUCTION OF LIBRARIES
- Publication number 20240352485
- Publication date Oct 24, 2024
- Flagship Pioneering Innovations VII, LLC
- Patrick Leo JONES
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Improved Expression Vectors and Uses Thereof
- Publication number 20240327496
- Publication date Oct 3, 2024
- Pfizer Inc.
- Kalpanie Ruwanmali Bandara
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ADAM6 MICE
- Publication number 20240306617
- Publication date Sep 19, 2024
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- B60 - VEHICLES IN GENERAL
Information Patent Application
PREPARATION OF LIBRARIES OF PROTEIN VARIANTS EXPRESSED IN EUKARYOTI...
- Publication number 20240294899
- Publication date Sep 5, 2024
- IONTAS LIMITED
- John McCafferty
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BACULOVIRUS EXPRESSION SYSTEM
- Publication number 20240294940
- Publication date Sep 5, 2024
- Bioverativ Therapeutics Inc.
- Tongyao Liu
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Means and Methods for Improved Regeneration
- Publication number 20240294931
- Publication date Sep 5, 2024
- VIB VZW
- Lieven De Veylder
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PROCESS FOR THE MANIPULATION OF NUCLEIC ACIDS
- Publication number 20240279686
- Publication date Aug 22, 2024
- GlaxoSmithKline Biologicals S.A.
- Amirreza FARIDMOAYER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR PREPARING TRANSGENIC NON-HUMAN ANIMAL HAVING GENOME INCL...
- Publication number 20240268360
- Publication date Aug 15, 2024
- Humab Co., Ltd.
- Chang Kyu OH
- C07 - ORGANIC CHEMISTRY
Information Patent Application
EXPRESSION VECTORS, BACTERIAL SEQUENCE-FREE VECTORS, AND METHODS OF...
- Publication number 20240229071
- Publication date Jul 11, 2024
- Mediphage Bioceuticals, Inc.
- Roderick SLAVCEV
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR RAPID GENERATION OF MODIFIABLE STABLE...
- Publication number 20240206439
- Publication date Jun 27, 2024
- DUKE UNIVERSITY
- Scott SODERLING
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
BETA-2 MICROGLOBULIN-DEFICIENT CELLS
- Publication number 20240207378
- Publication date Jun 27, 2024
- University of Washington through its Center for Commercialization
- David W. Russell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PLASMID SYSTEM WITHOUT SELECTABLE MARKERS AND PRODUCTION METHOD THE...
- Publication number 20240200083
- Publication date Jun 20, 2024
- Nanjing GenScript Biotech Co., Ltd.
- Fan Zhou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PRODUCING AND OPTIMIZING VIRAL VECTOR...
- Publication number 20240158759
- Publication date May 16, 2024
- iVexSol, Inc.
- Michael GREENE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Recombinant Cytomegalovirus Vectors As Vaccines For Tuberculosis
- Publication number 20240150789
- Publication date May 9, 2024
- International AIDS Vaccine Inititative, Inc.
- Thomas G. Evans
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TUNABLE TRANSPOSON SYSTEMS
- Publication number 20240141385
- Publication date May 2, 2024
- Aridis Pharmaceuticals, Inc.
- Kathy Ngo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
EFFICIENT NON-MEIOTIC ALLELE INTROGRESSION IN LIVESTOCK
- Publication number 20240057570
- Publication date Feb 22, 2024
- Recombinetics, Inc.
- Scott C. Fahrenkrug
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL CAS13B ORTHOLOGUES CRISPR ENZYMES AND SYSTEMS
- Publication number 20240018494
- Publication date Jan 18, 2024
- THE BROAD INSTITUTE, INC.
- David Benjamin Turitz Cox
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HUMANIZED LIGHT CHAIN MICE
- Publication number 20230337646
- Publication date Oct 26, 2023
- Regeneron Pharmaceuticals, Inc.
- Lynn Macdonald
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
PLATFORM VECTOR FOR MODULAR AND SIMPLIFIED INSERTION OF TRANSGENES...
- Publication number 20230313226
- Publication date Oct 5, 2023
- Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.
- Susanne Bailer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT ADENO-ASSOCIATED VIRAL VECTORS FOR MULTIPARTITE GENE DE...
- Publication number 20230287458
- Publication date Sep 14, 2023
- Abeona Therapeutics Inc.
- Linas PADEGIMAS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SINGLE GENERATION TARGETED GENE INTEGRATION
- Publication number 20230287459
- Publication date Sep 14, 2023
- The Jackson Laboratory
- Michael V. Wiles
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DISCOVERY AND ENGINEERING OF INTEGRASES FOR HIGH-EFFICIENCY GENE IN...
- Publication number 20230272435
- Publication date Aug 31, 2023
- Massachusetts Institute of Technology
- Omar Abudayyeh
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CELL LINES WITH MULTIPLE DOCKS FOR GENE INSERTION
- Publication number 20230227858
- Publication date Jul 20, 2023
- CATALENT PHARMA SOLUTIONS, LLC
- Gregory T. Bleck
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods and Compositions for Rapid Generation of Single and Multipl...
- Publication number 20230212524
- Publication date Jul 6, 2023
- RXCELL INC.
- Xianmin Zeng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Vector systems comprising sequences for excision in presence of a recombinase

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Non-human animals having a humanized signal-regulatory protein gene

Targeted integration of nucleic acids

Transgenic animals and methods of use

Non-human animals models of retinoschisis

Engineered DNA binding proteins

Targeted modification of rat genome

High-throughput mouse model for optimizing antibody affinities

Optogenetic construct for allosteric control of protein activity

Process for the manipulation of nucleic acids

ADAM6 mice

Means and methods for improved regeneration

Compositions and methods for producing genetically modified animals

Preparation of libraries of protein variants expressed in eukaryoti...

Preparation of libraries of protein variants expressed in eukaryoti...

Conditional CRISPR sgRNA expression

Lineage reporter synthetic chromosomes and methods of use

Methods of introducing multiple expression constructs into a eukary...

Recombinant cytomegalovirus vectors as vaccines for tuberculosis

Beta-2 microglobulin-deficient cells

Mammalian cells for producing adeno-associated viruses

High-throughput mouse model for optimizing antibody affinities

Cas13b orthologues CRISPR enzymes and systems

Targeted delivery of glycine receptors to excitable cells

Targeted gene therapies for pain and other neuro-related disorders

Inducible, tunable, and multiplex human gene regulation using CRISP...

Targeted integration into the PPP1R12C locus

Humanized light chain mice

Humanized light chain mice

Genetically modified T cell receptor mice

Methods and compositions for rapid generation of single and multipl...

Patents Applicationslast 30 patents

NEURODEGENERATIVE AND AMYOTROPHIC MODEL ANIMAL

ENGINEERED DNA BINDING PROTEINS

NON-MEIOTIC ALLELE INTROGRESSION

MAMMALIAN ARTIFICIAL CHROMOSOME VECTOR HAVING HUMAN IMMUNOGLOBULIN...

Genetically Engineered Eukaryotic Cells and Cell Lines and Uses The...

Novel Animal Model for Autoimmune Disease

COMPOSITIONS AND METHODS FOR THE PRODUCTION OF LIBRARIES

Improved Expression Vectors and Uses Thereof

ADAM6 MICE

PREPARATION OF LIBRARIES OF PROTEIN VARIANTS EXPRESSED IN EUKARYOTI...

BACULOVIRUS EXPRESSION SYSTEM

Means and Methods for Improved Regeneration

PROCESS FOR THE MANIPULATION OF NUCLEIC ACIDS

METHOD FOR PREPARING TRANSGENIC NON-HUMAN ANIMAL HAVING GENOME INCL...

EXPRESSION VECTORS, BACTERIAL SEQUENCE-FREE VECTORS, AND METHODS OF...

COMPOSITIONS AND METHODS FOR RAPID GENERATION OF MODIFIABLE STABLE...

BETA-2 MICROGLOBULIN-DEFICIENT CELLS

PLASMID SYSTEM WITHOUT SELECTABLE MARKERS AND PRODUCTION METHOD THE...

COMPOSITIONS AND METHODS FOR PRODUCING AND OPTIMIZING VIRAL VECTOR...

Recombinant Cytomegalovirus Vectors As Vaccines For Tuberculosis

TUNABLE TRANSPOSON SYSTEMS

EFFICIENT NON-MEIOTIC ALLELE INTROGRESSION IN LIVESTOCK

NOVEL CAS13B ORTHOLOGUES CRISPR ENZYMES AND SYSTEMS

HUMANIZED LIGHT CHAIN MICE

PLATFORM VECTOR FOR MODULAR AND SIMPLIFIED INSERTION OF TRANSGENES...

RECOMBINANT ADENO-ASSOCIATED VIRAL VECTORS FOR MULTIPARTITE GENE DE...

SINGLE GENERATION TARGETED GENE INTEGRATION

DISCOVERY AND ENGINEERING OF INTEGRASES FOR HIGH-EFFICIENCY GENE IN...

CELL LINES WITH MULTIPLE DOCKS FOR GENE INSERTION

Methods and Compositions for Rapid Generation of Single and Multipl...