viral genome or elements thereof as genetic vector

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C12N2770/00043

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2770/00ssRNA Viruses positive-sense

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C12N2770/00043viral genome or elements thereof as genetic vector

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Patents Grantslast 30 patents

Information Patent Grant
Method for producing CD4-positive T cells from pluripotent stem cells
- Patent number 11,987,811
- Issue date May 21, 2024
- Kyoto University
- Shin Kaneko
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Enhanced expression of RNA vectors
- Patent number 11,534,417
- Issue date Dec 27, 2022
- UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
- Peter Simmonds
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Viral based transient-expression vector system that allows multiple...
- Patent number 10,472,641
- Issue date Nov 12, 2019
- University of Florida Research Foundation, Incorporated
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Kits comprising plus-sense single stranded RNA viral vectors and me...
- Patent number 10,190,128
- Issue date Jan 29, 2019
- Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung E.V.
- Ulrich Commandeur
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Construction of new cucumber fruit mottle mosaic virus derived subg...
- Patent number 10,174,332
- Issue date Jan 8, 2019
- Chung-ang University Industry Academic Cooperation Foundation
- Gung Pyo Lee
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Production of an immunogen using a plant virus
- Patent number 10,117,923
- Issue date Nov 6, 2018
- VACPLANTA LIMITED
- Petr Alexeevich Ivanov
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Citrus tristeza virus based vectors for foreign gene/s expression
- Patent number 10,017,747
- Issue date Jul 10, 2018
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Calcium formate as a supplement to prevent neural tube defects
- Patent number 9,895,328
- Issue date Feb 20, 2018
- Board of Regents, The University of Texas System
- Dean R. Appling
- A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information Patent Grant
System for expression of genes in plants
- Patent number 9,765,349
- Issue date Sep 19, 2017
- iBio, Inc.
- Oleg Fedorkin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Viral based transient-expression vector system that allows multiple...
- Patent number 9,611,483
- Issue date Apr 4, 2017
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cardiac repair by reprogramming of cardiac fibroblasts into cardiom...
- Patent number 9,523,079
- Issue date Dec 20, 2016
- The Board of Regents of the University of Texas System
- Young-Jae Nam
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods related to viruses of the genus Negevirus
- Patent number 9,388,428
- Issue date Jul 12, 2016
- The Board of Regents of the University of Texas System
- Farooq Nasar
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Minicircles with viral expression cassettes and their use in the tr...
- Patent number 9,382,552
- Issue date Jul 5, 2016
- PlasmidFactory GmbH + Co KG
- Martin Schleef
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cardiac repair by reprogramming of cardiac fibroblasts into cardiom...
- Patent number 9,017,661
- Issue date Apr 28, 2015
- The Board of Regents of the University of Texas System
- Young-Jae Nam
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Viral-based transient-expression vector system for trees
- Patent number 8,629,334
- Issue date Jan 14, 2014
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus vector and use thereof
- Patent number 8,586,826
- Issue date Nov 19, 2013
- Japan Science and Technology Agency
- Masashi Mori
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Viral based transient-expression vector system that allows multiple...
- Patent number 8,389,804
- Issue date Mar 5, 2013
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Plant virus coat fusion proteins with GDF8 epitopes and vaccines th...
- Patent number 7,432,079
- Issue date Oct 7, 2008
- Schering-Plough Animal Health Corporation
- David E. Junker
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Recombinant viral nucleic acids
- Patent number 7,192,740
- Issue date Mar 20, 2007
- Large Scale Biology Corporation
- Jonathan Donson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Viral expression vectors
- Patent number 7,132,588
- Issue date Nov 7, 2006
- Large Scale Biology Corporation
- Wayne P. Fitzmaurice
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cytoplasmic inhibition of gene expression
- Patent number 6,720,183
- Issue date Apr 13, 2004
- Large Scale Biology Corporation
- Monto H. Kumagai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Viral expression vectors
- Patent number 6,656,726
- Issue date Dec 2, 2003
- Large Scale Biology Corporation
- Wayne P. Fitzmaurice
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cytoplasmic inhibition of gene expression by viral RNA
- Patent number 6,479,291
- Issue date Nov 12, 2002
- Large Scale Biology Corporation
- Monto H. Kumagai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cytoplasmic inhibition of gene expression in a plant
- Patent number 6,376,752
- Issue date Apr 23, 2002
- Large Scale Biology Corporation
- Monto H. Kumagai
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method of modulating an immune response in an infected mammal by tr...
- Patent number 6,355,248
- Issue date Mar 12, 2002
- Thomas Jefferson University
- Frank Michaels
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Recombinant animal viral nucleic acids
- Patent number 6,284,492
- Issue date Sep 4, 2001
- Large Scale Biology Corporation
- Jon Donson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Recombinant animal viral nucleic acids
- Patent number 6,054,566
- Issue date Apr 25, 2000
- Biosource Technologies, Inc.
- Jon Donson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Cytoplasmic inhibition of gene expression
- Patent number 5,922,602
- Issue date Jul 13, 1999
- Biosource Technologies, Inc.
- Monto Hiroshi Kumagai
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Recombinant plant viral nucleic acids
- Patent number 5,889,190
- Issue date Mar 30, 1999
- Biosource Technologies, Inc.
- Jon Donson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Recombinant plant viral nucleic acids
- Patent number 5,866,785
- Issue date Feb 2, 1999
- Biosource Technologies, Inc.
- Jon Donson
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
PLANT VECTORS, COMPOSITIONS AND USES RELATING THERETO
- Publication number 20240381876
- Publication date Nov 21, 2024
- University of Maryland, College Park
- Anne Elizabeth SIMON
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
MOBILE ENDONUCLEASES FOR HERITABLE MUTATIONS
- Publication number 20240150740
- Publication date May 9, 2024
- Keygene N.V.
- Julia Johanna WIND
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Polyethylene Glycol Conjugates of Polyethyleneimine and Their Use i...
- Publication number 20230120141
- Publication date Apr 20, 2023
- Charles River Laboratories, Inc.
- Aslam ANSARI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENERATION OF HERITABLY GENE-EDITED PLANTS WITHOUT TISSUE CULTURE
- Publication number 20210348177
- Publication date Nov 11, 2021
- The Regents of the University of California
- Mily RON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BARLEY STRIPE MOSAIC VIRUS-BASED GENE EDITING VECTOR SYSTEM
- Publication number 20210348176
- Publication date Nov 11, 2021
- CHINA AGRICULTURAL UNIVERSITY
- Yongliang Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VECTORS AND METHODS FOR GENE EXPRESSION IN MONOCOTS
- Publication number 20200270621
- Publication date Aug 27, 2020
- Rothamsted Research Limited
- Konstantin Kanyuka
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD OF IMPROVING POTEXVIRAL VECTOR STABILITY
- Publication number 20200255847
- Publication date Aug 13, 2020
- NOMAD BIOSCIENCE GMBH
- Stefano Torti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR VIRAL-BASED GENE EDITING IN PLANTS
- Publication number 20190093117
- Publication date Mar 28, 2019
- R.J. Reynolds Tobacco Company
- Xingpeng Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENHANCED EXPRESSION OF RNA VECTORS
- Publication number 20190060262
- Publication date Feb 28, 2019
- UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
- Peter Simmonds
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CITRUS TRISTEZA VIRUS BASED VECTORS FOR FOREIGN GENE/S EXPRESSION
- Publication number 20180355325
- Publication date Dec 13, 2018
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR PRODUCING CD4-POSITIVE T CELLS FROM PRURIPOTENT STEM CELLS
- Publication number 20180298337
- Publication date Oct 18, 2018
- KYOTO UNIVERSITY
- Shin KANEKO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Viral Based Transient-Expression Vector System That Allows Multiple...
- Publication number 20170298370
- Publication date Oct 19, 2017
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FOXTAIL MOSAIC VIRUS-BASED VECTORS FOR GENE SILENCING AND GENE EXPR...
- Publication number 20170211081
- Publication date Jul 27, 2017
- Iowa State University Research Foundation, Inc.
- John Hemmingson Hill
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Construction of New Cucumber Fruit Mottle Mosaic Virus Derived Subg...
- Publication number 20170121725
- Publication date May 4, 2017
- CHUNG-ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
- Gung Pyo Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM FOR EXPRESSION OF GENES IN PLANTS
- Publication number 20170121721
- Publication date May 4, 2017
- IBIO, INC.
- Oleg Fedorkin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
KITS COMPRISING PLUS-SENSE SINGLE STRANDED RNA VIRAL VECTORS AND ME...
- Publication number 20160145635
- Publication date May 26, 2016
- Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.
- Ulrich COMMANDEUR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Enhanced Expression Of RNA Vectors
- Publication number 20160053281
- Publication date Feb 25, 2016
- The University Court Of The University Of Edinburgh
- Peter Simmonds
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Production of an Immunogen Using a Plant Virus
- Publication number 20150274784
- Publication date Oct 1, 2015
- VACPLANTA LIMTED
- Petr Alexeevich Ivanov
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MINICIRCLES WITH VIRAL EXPRESSION CASSETTES AND THEIR USE IN THE TR...
- Publication number 20150218586
- Publication date Aug 6, 2015
- PLASMIDFACTORY GMBH & CO. KG
- MARTIN SCHLEEF
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CITRUS TRISTEZA VIRUS BASED VECTORS FOR FOREIGN GENE/S EXPRESSION
- Publication number 20150096078
- Publication date Apr 2, 2015
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS RELATED TO VIRUSES OF THE GENUS NEGEVIRUS
- Publication number 20140227765
- Publication date Aug 14, 2014
- The Board of Regents of the University of Texas System
- Farooq Nasar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Viral Based Transient-Expression Vector System That Allows Multiple...
- Publication number 20130219556
- Publication date Aug 22, 2013
- University of Florida Research Foundation, Inc.
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Cardiac Repair By Reprogramming of Cardiac Fibroblasts Into Cardiom...
- Publication number 20120213738
- Publication date Aug 23, 2012
- Young-Jae Nam
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
VIRAL BASED TRANSIENT-EXPRESSION VECTOR SYSTEM THAT ALLOWS MULTIPLE...
- Publication number 20120204287
- Publication date Aug 9, 2012
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VIRUS VECTOR AND USE THEREOF
- Publication number 20110107466
- Publication date May 5, 2011
- Masashi Mori
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Papaya Mosaic Virus-Based Vaccines for Influenza
- Publication number 20100111996
- Publication date May 6, 2010
- Denis Leclerc
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
VIRAL-BASED TRANSIENT-EXPRESSION VECTOR SYSTEM FOR TREES
- Publication number 20100017911
- Publication date Jan 21, 2010
- William O. Dawson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Neutralizing Epitope-Based Growth Enhancing Vaccine
- Publication number 20090208522
- Publication date Aug 20, 2009
- Schering-Plough Animal Health Corporation
- David E. Junker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PLANT VIRAL PARTICLES COMPRISING A PLURALITY OF FUSION PROTEINS CON...
- Publication number 20090062514
- Publication date Mar 5, 2009
- Icon Genetics GmbH
- Stefan Werner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Neutralizing epitope-based growth enhancing vaccine
- Publication number 20060159696
- Publication date Jul 20, 2006
- David E. Junker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

viral genome or elements thereof as genetic vector

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Method for producing CD4-positive T cells from pluripotent stem cells

Enhanced expression of RNA vectors

Viral based transient-expression vector system that allows multiple...

Kits comprising plus-sense single stranded RNA viral vectors and me...

Construction of new cucumber fruit mottle mosaic virus derived subg...

Production of an immunogen using a plant virus

Citrus tristeza virus based vectors for foreign gene/s expression

Calcium formate as a supplement to prevent neural tube defects

System for expression of genes in plants

Viral based transient-expression vector system that allows multiple...

Cardiac repair by reprogramming of cardiac fibroblasts into cardiom...

Compositions and methods related to viruses of the genus Negevirus

Minicircles with viral expression cassettes and their use in the tr...

Cardiac repair by reprogramming of cardiac fibroblasts into cardiom...

Viral-based transient-expression vector system for trees

Virus vector and use thereof

Viral based transient-expression vector system that allows multiple...

Plant virus coat fusion proteins with GDF8 epitopes and vaccines th...

Recombinant viral nucleic acids

Viral expression vectors

Cytoplasmic inhibition of gene expression

Viral expression vectors

Cytoplasmic inhibition of gene expression by viral RNA

Cytoplasmic inhibition of gene expression in a plant

Method of modulating an immune response in an infected mammal by tr...

Recombinant animal viral nucleic acids

Recombinant animal viral nucleic acids

Cytoplasmic inhibition of gene expression

Recombinant plant viral nucleic acids

Recombinant plant viral nucleic acids

Patents Applicationslast 30 patents

PLANT VECTORS, COMPOSITIONS AND USES RELATING THERETO

MOBILE ENDONUCLEASES FOR HERITABLE MUTATIONS

Polyethylene Glycol Conjugates of Polyethyleneimine and Their Use i...

GENERATION OF HERITABLY GENE-EDITED PLANTS WITHOUT TISSUE CULTURE

BARLEY STRIPE MOSAIC VIRUS-BASED GENE EDITING VECTOR SYSTEM

VECTORS AND METHODS FOR GENE EXPRESSION IN MONOCOTS

METHOD OF IMPROVING POTEXVIRAL VECTOR STABILITY

METHODS AND COMPOSITIONS FOR VIRAL-BASED GENE EDITING IN PLANTS

ENHANCED EXPRESSION OF RNA VECTORS

CITRUS TRISTEZA VIRUS BASED VECTORS FOR FOREIGN GENE/S EXPRESSION

METHOD FOR PRODUCING CD4-POSITIVE T CELLS FROM PRURIPOTENT STEM CELLS

Viral Based Transient-Expression Vector System That Allows Multiple...

FOXTAIL MOSAIC VIRUS-BASED VECTORS FOR GENE SILENCING AND GENE EXPR...

Construction of New Cucumber Fruit Mottle Mosaic Virus Derived Subg...

SYSTEM FOR EXPRESSION OF GENES IN PLANTS

KITS COMPRISING PLUS-SENSE SINGLE STRANDED RNA VIRAL VECTORS AND ME...

Enhanced Expression Of RNA Vectors

Production of an Immunogen Using a Plant Virus

MINICIRCLES WITH VIRAL EXPRESSION CASSETTES AND THEIR USE IN THE TR...

CITRUS TRISTEZA VIRUS BASED VECTORS FOR FOREIGN GENE/S EXPRESSION

COMPOSITIONS AND METHODS RELATED TO VIRUSES OF THE GENUS NEGEVIRUS

Viral Based Transient-Expression Vector System That Allows Multiple...

Cardiac Repair By Reprogramming of Cardiac Fibroblasts Into Cardiom...

VIRAL BASED TRANSIENT-EXPRESSION VECTOR SYSTEM THAT ALLOWS MULTIPLE...

VIRUS VECTOR AND USE THEREOF

Papaya Mosaic Virus-Based Vaccines for Influenza

VIRAL-BASED TRANSIENT-EXPRESSION VECTOR SYSTEM FOR TREES

Neutralizing Epitope-Based Growth Enhancing Vaccine

PLANT VIRAL PARTICLES COMPRISING A PLURALITY OF FUSION PROTEINS CON...

Neutralizing epitope-based growth enhancing vaccine