Claims
- 1-31. (Canceled)
- 32. A DNA segment comprising an adenoviral ITR and a p53 coding region, the coding region positioned under the control of a CMV promoter.
- 33. The DNA segment of claim 32, further comprising a polyadenylation signal position 3′ of the p53 coding region.
- 34. The DNA segment of claim 32, which does not contain a functional adenoviral E1 coding region.
- 35. The DNA segment of claim 32, wherein the adenoviral ITR region is a left end ITR.
- 36. The DNA segment of claim 32, further comprising an E1 enhancer.
- 37. The DNA segment of claim 32, wherein the DNA segment is an expression vector.
- 38. The DNA segment of claim 35, further comprising an E2 adenoviral gene.
- 39. The DNA segment of claim 38, further comprising an E4 adenoviral gene.
- 40. The DNA segment of claim 37, wherein the expression vector is an adenovirus expression vector.
- 41. The DNA segment of any one of claims 32 through 40, wherein the DNA is packaged in an adenovirus.
Parent Case Info
[0001] This application is a continuation-in-part of U.S. Ser. No. 08/233,777, filed May 19, 1994, which is a continuation-in-part of U.S. Ser. No. 08/142,669 filed Oct. 25, 1993, the contents of which are hereby incorporated by reference into the present disclosure.
Divisions (1)
|
Number |
Date |
Country |
Parent |
08328673 |
Oct 1994 |
US |
Child |
08958570 |
Oct 1997 |
US |
Continuations (1)
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Number |
Date |
Country |
Parent |
08958570 |
Oct 1997 |
US |
Child |
10766363 |
Jan 2004 |
US |
Continuation in Parts (2)
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Number |
Date |
Country |
Parent |
08246006 |
May 1994 |
US |
Child |
08328673 |
Oct 1994 |
US |
Parent |
08142669 |
Oct 1993 |
US |
Child |
08246006 |
May 1994 |
US |