The present document relates to systems and methods for a flexible pressure sensor that measures normal and shear forces, and in particular to systems and methods for a resistive microcracked pressure sensor that includes a metallic conductor having a plurality of microcracks that are formed during manufacture for increasing the change in resistance of the metallic conductor to high magnitude forces.
The field of biomimetic engineering is rapidly expanding and holds great promise in a number of fields, but perhaps most strongly in the area of biomedical engineering that deals with medical rehabilitation. In designing systems to replace and/or interact with biological systems, a biomimetic approach not only may yield good performance, but it may also contribute to the field of biomimetic engineering by developing skin-like sensate materials.
Loss of sensation in the feet leads to secondary complications for individuals suffering from diabetes, stroke, and spinal cord injury. The loss of sensation is due either to damage to somatosensory neurons in the periphery (e.g., in the case of diabetes) or by damage to the somatosensory central nervous system pathways caused by traumatic injury or cerebrovascular accident. Impairments to motor control can also result from spinal cord or brain injury, stroke, Parkinson's disease, multiple sclerosis, or cerebral palsy. Systems that provide sensory substitution may be able to avert or reduce the secondary complications due to loss of sensation. In addition, systems that provide neuromotor assistance by neuromuscular stimulation during locomotion may improve the safety or efficiency of gait of an individual. Both types of applications require the use of a sensor that is reliable and biocompatible.
Measurements of plantar pressure can provide signals that are useful either in systems that provide sensory substitution or in systems that provide neuromotor assistance. These strategies for treatment of peripheral neuropathy or neuromotor disability require a sensor to measure plantar pressure patterns on the sole of the foot. The sensor should provide measures of pressure at critical locations under the sole of the foot (e.g., heel, metatarsals) and should be reliable and durable to enable everyday use. For applications that would utilize body-worn technology, the sensor system should be made of a material that is suitable for use in an insole inserted in the shoe. The primary design issues here would be that the material should be suitable for skin contact (i.e., should not cause any adverse reaction with the skin) and the elastic modulus of the material should be comparable to that of the sole of the foot in order to facilitate the distribution of pressure and for comfort of the individual.
For applications that would utilize implanted technology, the biocompatibility and mechanical interface issues still remain, yet the demands are more pronounced. Plantar pressure can be measured by mechanical, optical, acoustical, pneumatic, and electrical means. Measuring pressure by electrical means is the most widely used technology because of the robustness and ease of fabrication of the sensor as well as the accuracy and sensitivity of the measurement. Most plantar pressure sensors that use electrical means fall into one of three categories: resistive, piezoelectric or capacitive. In these sensors, an applied pressure causes a change in resistance (in a conductor), in voltage (in a piezoelectric material) or in capacitance (in a capacitor). Pressure sensors that use the change in resistance of a conducting material as a method of transduction often use designs akin to conventional strain gage. In resistive metallic pressure gages, the pressure applied to a metallic conductor results in a change in its dimensions due to Poisson compression which causes the resistance to increase.
Another type of resistive pressure gage uses a conductive elastomer as a resistor. In these types of pressure gages, silicone is loaded with a conductive material such as carbon. Pressure applied to the surface causes the distance between the carbon particles to decrease, thereby reducing the resistance of the elastomer. However, the sensitivity of this pressure sensor decreases significantly and shows a large hysteresis when the applied pressure is above 200 kPa. In piezoresistive pressure gages, pressure applied to a semiconductor strains the lattice which increases the mobility of the charge carriers, thereby reducing the resistance. In piezoelectric pressure gages, pressure applied to a piezoelectric material induces a voltage across the material by separating charges. The first plantar pressure measurement using this technology was reported in 1975. It's been known that the charge, and hence the voltage, decreases over time due to leakage, which is why piezoelectric transducers are better suited for dynamic rather than static measurements.
In capacitive pressure gages, the changes in the capacitance of a capacitor may be measured. In particular, an applied pressure compresses the dielectric, i.e., which reduces the distance between the metal electrodes of the gage, and hence increases the capacitance. Capacitive pressure gages have been used for plantar pressure measurements for a long time. A recently developed capacitive pressure sensor consists of four air-gap capacitors that are embedded in a silicone matrix. This pressure sensor is capable of measuring both normal and shear forces of up to 50 kPa. However, this is not sufficient because the forces that need to be measured by plantar pressure sensors usually exceed 1 MPa. In another type of capacitive pressure gage, the change in capacitance between two metal plates on a silicone substrate with an air gap in between was monitored. The capacitance of this sensor changes linearly with the applied pressure in the range of 0 to 160 kPa. The drawbacks of this method are that (a) the capacitance changes only by about 10% over the investigated pressure range, i.e., the sensor is not very sensitive, (b) the pressure range is low (only up to 160 kPa), and (c) no shear force measurements can be carried out using this system.
While great progress has been made over the last 10 years in data acquisition, transmission and analysis, progress on the sensor itself has been largely incremental. In particular, none of the commercially available plantar pressure sensors are suitable for long-term measurements. In addition, all in-shoe pressure sensors are just that, to be used only in the shoe. A pressure sensor that could be permanently implanted into the sole of the foot could greatly improve the usability and reliability of the system and it could enable usage in a broader range of medical applications. Besides not being implantable, most current pressure sensors have other limitations for biomedical applications. Research on sensors that use piezoresistive or capacitive sensing technology has focused on silicon-based devices.
Silicon-based sensors are not well suited for many biomedical applications because they are mechanically brittle and typically cannot sustain large deformations and sudden impact. The substrates and encapsulating materials for many pressure sensors used for biomedical or robotic applications are made of plastics such as polyimide. Polyimide has an elastic modulus of 3-5 GPa. Skin has an elastic modulus of a few tens of kPa to several hundred kPa, i.e., the elasticity of skin is 4-5 orders of magnitude lower than the plastic materials that typically compose the bulk of an in-shoe pressure sensor. If such a sensor were implanted, the mismatch in mechanical properties of the sensor and the skin would result in patient discomfort and potentially inflammatory reactions of the body tissue. To summarize, the ultimate plantar pressure sensor should (a) have mechanical properties similar to human skin, (b) be capable of reliably and accurately measuring high (>1 Mpa) and low (<10 kPa) normal and shear pressures, and (c) have a low hysteresis, and negligible drift. While currently available sensors possess one or two of these properties, no sensor to date can achieve all these properties. To address these limitations of conventional pressure sensors, we propose to develop a pressure sensor that largely consists of two layers of a soft, biocompatible elastomer material that encapsulates one or more metallic conductors with a microcracked structure capable of measuring high magnitude normal and shear forces.
Corresponding reference characters indicate corresponding elements among the view of the drawings. The headings used in the figures do not limit the scope of the claims.
In general, embodiments of a resistive microcracked pressure sensor that provide for a system and method for measuring high and low magnitude normal and shear forces applied against an elastomer substrate based on the change in resistance detected from a metallic conductor encapsulated within the elastomer substrate of the pressure sensor are described herein. Referring to the drawings, embodiments of the resistive microcracked pressure sensor are illustrated and generally indicated as 100 and 200 in
Referring to
In one aspect, the metallic conductor 114 is manufactured to have a microcracked structure (
As shown in
As shown in
In some embodiments, the pressure sensor 100 may be manufactured to have the following dimensions: lower elastomer layer 116 has a depth of about 1 mm; metallic conductor 114 has a depth of between 600 to 900 Å; upper elastomer layer 118 has a depth of about 5 mm, and the elastomer substrate 104 has an overall depth of about 6 mm.
Referring to
As shown in
The pressure sensors 100 and 200 have several advantages that would greatly improve in-shoe sensors, would provide a convenient and comfortable means of measuring contact forces on the skin using a body-worn pressure sensor, and could be made to be totally implantable:
1. Reduced mechanical mismatch: Matching the mechanical properties of the pressure sensor 200 with those of the tissue on the sole of the foot improves patient comfort and reduces the potential for inflammatory reactions. An estimated >99% of the thickness of the proposed pressure gage consists of two layers of silicone (the first layer is the substrate and the second layer is the outer encapsulation). Each of these two layers has an elastic modulus of about 1 MPa which is very close to the elastic modulus of skin and more than three orders of magnitude lower than currently available in-shoe sensors. The silicone substrate material is available in implantable medical grade making it suitable for implantations.
2. Improved precision and accuracy of pressure measurement. The precision and accuracy of the pressure measurement is of utmost importance for sensors used in robotics, prosthesis or biomedical rehabilitation devices. In the pressure gage of the pressure sensor 200, the electrical resistance of the metallic conductors 210 made of a deposited gold film sandwiched between the elastomer layers of the elastomer substrate 204 increases nearly linearly with strain. In addition, the slope of the increase is neither too large nor too small, thus pressure measurements are precise, and accurate over a large strain range.
3. Improved sensitivity of pressure measurement. The gage factor F is used to quantify the sensitivity of a pressure/strain gage. The gage factor of the pressure sensor 200 is larger than that of the conventional metal gages. In some embodiments, the estimated gage factor for the resistive metal gage on elastomeric silicone is between 5 and over 20. The exact value depends on the dimensions of the metallic conductors 210. The gage factor for conventional metal gages is typically 2, but no more than 5. The increase in electrical resistance in these conventional pressure gages is mainly caused by changes in the physical dimensions of the metal under strain. The reason for the higher gage factor in the silicone-based gage of the pressure sensor 200 is that the increase in resistance under strain is not only caused by a change in the dimensions of the metallic conductor 210, but also by the lengthening of micro-cracks in the metal of the metallic conductor 210 (
4. Improved shear force measurement normal and shear forces are two components of plantar pressure and both contribute to ulcer formation in the diabetic foot. To reduce or prevent ulcer formation, we need to be able to reliably measure these forces. Many pressure sensing technologies are capable of accurately and precisely measuring normal forces. However, measuring shear forces is considerably more challenging. Currently available shear force sensors often require complicated computations to extract the applied shear force which limits their applicability in clinical settings. In addition, these sensors are typically made of brittle, semiconducting materials such as silicon, which further limits their usability for biomedical applications.
In addition, measuring shear forces is considerably more challenging since currently available shear force sensors often require complicated computations to extract the applied shear force which limits their applicability in clinical settings. In addition, these sensors are typically made of brittle, semiconducting materials such as silicon, which further limits their usability for biomedical applications.
The pressure sensor 200 has exhibited the following properties: (1) accurate and precise measurement of normal pressure as well as shear forces, (2) high repeatability of the measurement, (3) no hysteresis, and (4) being soft and compliant. Embodiments of a silicone-based pressure sensor 200 described herein possess these properties.
In one embodiment, the entire pressure sensor 200 includes a soft elastomer poly(dimethylsiloxane) (PDMS, Sylgard 184, Dow Corning), a thin (<120 nm) Au film or metallic components 210A and 210B, and an adhesion layer (Cr or Ti, 1-5 nm thick) in contact with the Au film. The use of PDMS as an elastomer substrate 204 has a number of advantages. In particular, PDMS is chemically inert, elastically stretchable to >100% strain, biocompatible and thermally stable (from −55 to 200 degree celsius). It is available in implantable grade from different suppliers and has an elastic modulus similar to human skin (tunable from an elastic modulus <0.5 MPa to >5 MPa).
A second metal stack 202B (the top conductor 210B) of 1-5 nm Cr or Ti, <120 nm of gold is deposited through a shadow mask by electron beam evaporation, thermal evaporation, or sputtering (
There are two important factors for the pressure sensor 200 to function properly:
1. Morphology of the gold metallic conductor—The gold metallic conductors 210A and 210B must have a micro-cracked morphology (
2. Thickness ratio of PDMS substrate: Au—The thickness of the insulation layer 218 and the lower and upper elastomer layers 214 and 216 that encapsulate the insulation layer 218 must be carefully chosen for the gold metallic conductors 210A and 210B to remain electrically conducting. If the PDMS covering the gold metallic conductors 210A and 210B are thicker than about 0.5 mm, both thick (>70 nm) and thin (20-50 nm) gold metallic conductors 210A and 210B will lose their electrical conduction after the PDMS substrate 204 is cured, rendering the resistive microcracked sensor 200 non-functioning. If the PDMS substrate 204 covering the gold metallic conductors 210A and 210B are 100-300 μm thick, only the thin (20-50 nm) gold metallic conductors 210A and 210B lose their electrical conduction whereas the thicker gold metallic conductors 210A and 210B remain electrically conducting. This finding is important for the fabrication of the pressure sensor 200. The minimum required thickness of the gold metallic conductors 210A and 210B for the pressure sensor 200 to function properly depends on the thickness of the overlying silicone: the thicker the silicone layer, the thicker the gold metallic conductors 210A and 210B must be. In one embodiment of the biomimetic pressure sensor, the gold metallic conductors 210A and 210B must have a minimum thickness (>70 nm), and the thickness of the PDMS substrate 204 that the gold metallic conductors 210A and 210B are in contact with before curing must generally be less than about 0.5 mm. For this reason, two encapsulation layers are required after the second gold deposition: (i) a thin encapsulation layer (100-300 μm) that is first cured to allow the gold metallic conductor 210A underneath to become stable, and (ii) a thick encapsulation layer that protects the first layer and then brings the pressure sensor 200 to the desired overall dimension.
The capability of this “skin-like” resistive microcracked pressure sensor 200 to measure normal and shear forces was evaluated. The two perpendicularly-oriented gold metallic conductors 210A and 210B represent the actual pressure/force sensing element. Each metallic conductor 210A and 210B is 20 mm long and 1 mm wide with 4 mm×4 mm wide pads to which the electrical contact is made (
We used the setup described in
It should be understood from the foregoing that, while particular embodiments have been illustrated and described, various modifications can be made thereto without departing from the spirit and scope of the invention as will be apparent to those skilled in the art. Such changes and modifications are within the scope and teachings of this invention as defined in the claims appended hereto.
This is a non-provisional application that claims benefit to U.S. provisional patent application Ser. No. 61/807,540, filed on Apr. 2, 2013 and is herein incorporated by reference in its entirety.
Number | Date | Country | |
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61807540 | Apr 2013 | US |