containing an intein ("protein splicing")domain

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C07K2319/92

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2319/00Fusion polypeptide

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C07K2319/92containing an intein ("protein splicing")domain

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Patents Grantslast 30 patents

Information Patent Grant
Proximity-based sortase-mediated protein purification and ligation
- Patent number 12,187,809
- Issue date Jan 7, 2025
- The Trustees of the University of Pennsylvania
- Andrew Tsourkas
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Protein complex including botulinum toxin translocation domain and...
- Patent number 12,171,814
- Issue date Dec 24, 2024
- MVRIX CO., LTD.
- Dae Hyuk Kweon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Split inteins, conjugates and uses thereof
- Patent number 12,054,541
- Issue date Aug 6, 2024
- The Trustees of Princeton University
- Tom W. Muir
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Oncolytic group B adenovirus expressing a stroma-targeted bispecifi...
- Patent number 12,049,513
- Issue date Jul 30, 2024
- AKAMIS BIO LIMITED
- Brian Robert Champion
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Split-immunotoxins for boosting oncolytic virus toxicity
- Patent number 12,037,370
- Issue date Jul 16, 2024
- Research Institute at Nationwide Children's Hospital
- Dmitri Kudryashov
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genome editing without nucleases
- Patent number 12,031,146
- Issue date Jul 9, 2024
- The Board of Trustees of the Leland Stanford Junior University
- Adi Barzel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Soluble intein fusion proteins and methods for purifying biomolecules
- Patent number 11,926,854
- Issue date Mar 12, 2024
- Merck Patent GmbH
- Martin Zillmann
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Adenovirus armed with bispecific T cell activator
- Patent number 11,840,702
- Issue date Dec 12, 2023
- AKAMIS BIO LIMITED
- Brian Champion
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antigen delivery platforms
- Patent number 11,639,370
- Issue date May 2, 2023
- GlaxoSmithKline Biologicals SA
- Michael Franti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CAS9 proteins including ligand-dependent inteins
- Patent number 11,578,343
- Issue date Feb 14, 2023
- President and Fellows of Harvard College
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bivalent bispecific antibody hybrid protein expression and preparat...
- Patent number 11,535,674
- Issue date Dec 27, 2022
- Shanghai Jiao Tong University
- Lei Han
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Split intein mediated polymerization and production of mussel foot...
- Patent number 11,530,245
- Issue date Dec 20, 2022
- Washington University
- Fuzhong Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Soluble intein fusion proteins and methods for purifying biomolecules
- Patent number 11,326,154
- Issue date May 10, 2022
- Merck Patent GmbH
- Martin Zillmann
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
AAV delivery of nucleobase editors
- Patent number 11,306,324
- Issue date Apr 19, 2022
- President and Fellows of Harvard College
- David R. Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Proximity-based sortase-mediated protein purification and ligation
- Patent number 11,236,177
- Issue date Feb 1, 2022
- The Trustees of the University of Pennsylvania
- Andrew Tsourkas
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method using split inteins to generate protein conjugates
- Patent number 11,161,899
- Issue date Nov 2, 2021
- The Trustees of Princeton University
- Tom W. Muir
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Split inteins with exceptional splicing activity
- Patent number 11,142,550
- Issue date Oct 12, 2021
- The Trustees of Princeton University
- Tom W. Muir
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fusion proteins comprising a Mtu ΔI-CM intein variant and methods o...
- Patent number 11,136,360
- Issue date Oct 5, 2021
- Tsinghua University
- Zhanglin Lin
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Chromatography resin, production and use thereof
- Patent number 11,124,539
- Issue date Sep 21, 2021
- CYTIVA BIOPROCESS R&D AB
- Johan William Ohman
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Split inteins with exceptional splicing activity
- Patent number 11,084,849
- Issue date Aug 10, 2021
- The Trustees of Princeton University
- Tom W. Muir
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antigen delivery platforms
- Patent number 11,078,237
- Issue date Aug 3, 2021
- GlaxoSmithKline Biologicals SA
- Michael Franti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for stabilizing trans-splicing intein modi...
- Patent number 11,066,657
- Issue date Jul 20, 2021
- Agrivida, Inc.
- R. Michael Raab
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Intein-modified proteases, their production and industrial applicat...
- Patent number 10,851,362
- Issue date Dec 1, 2020
- Agrivida, Inc.
- R. Michael Raab
- A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information Patent Grant
Methods and compositions for stabilizing trans-splicing intein modi...
- Patent number 10,731,143
- Issue date Aug 4, 2020
- Agrivida, Inc.
- R. Michael Raab
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
CAS9 proteins including ligand-dependent inteins
- Patent number 10,704,062
- Issue date Jul 7, 2020
- President and Fellows of Harvard College
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method and system for the production of recombinant proteins by cells
- Patent number 10,696,997
- Issue date Jun 30, 2020
- Universite Libre de Bruxelles
- Laurence Van Melderen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Genome editing without nucleases
- Patent number 10,612,041
- Issue date Apr 7, 2020
- The Board of Trustees of the Leland Stanford Junior University
- Adi Barzel
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method of using split inteins, conjugates to generate protein conju...
- Patent number 10,526,401
- Issue date Jan 7, 2020
- The Trustees of Princeton University
- Tom W. Muir
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Protein purification using intein-hydrophobin tag and alcohol preci...
- Patent number 10,479,815
- Issue date Nov 19, 2019
- Sareh Arjmand
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Precipitable peptides
- Patent number 10,358,461
- Issue date Jul 23, 2019
- The Trustees of Columbia University In the City of New York
- Scott Banta
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
ADENOVIRUS ARMED WITH BISPECIFIC T CELL ACTIVATOR
- Publication number 20250026851
- Publication date Jan 23, 2025
- AKAMIS BIO LIMITED
- Brian Robert CHAMPION
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS COMPRISING LIPID ASSOCIATED TRANSMEMBRANE...
- Publication number 20240352086
- Publication date Oct 24, 2024
- The Regents of the University of California
- Kira Podolsky
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR CELL-BASED DELIVERY SYSTEMS
- Publication number 20240342220
- Publication date Oct 17, 2024
- Washington University
- Farshid Guilak
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Recombinant Vectors Comprising Polycistronic Expression Cassettes a...
- Publication number 20240316199
- Publication date Sep 26, 2024
- Alaunos Therapeutics, Inc.
- Simon OLIVARES
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSION PROTEINS COMPRISING AN INTEIN POLYPEPTIDE AND METHODS OF USE...
- Publication number 20240200102
- Publication date Jun 20, 2024
- PAIRWISE PLANTS SERVICES, INC.
- Yongjoo Kim
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR (CAR)-T CELLS
- Publication number 20240181056
- Publication date Jun 6, 2024
- Imperial College Innovations Limited
- Xiaoning Xu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS COMPRISING SPLICING-DERIVED ANTIGENS FOR T...
- Publication number 20240182518
- Publication date Jun 6, 2024
- The Regents of the University of California
- Yi XING
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Adenovirus armed with bispecific T cell activator
- Publication number 20240175052
- Publication date May 30, 2024
- AKAMIS BIO LIMITED
- Brian CHAMPION
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PROTEIN PURIFICATION USING A SPLIT INTEIN SYSTEM
- Publication number 20240132538
- Publication date Apr 25, 2024
- Cytiva BioProcess R&D AB
- Christopher James Sevinsky
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CRISPR/CAS9-MEDIATED MEANS AND METHODS FOR CELL REPROGRAMMING
- Publication number 20240124891
- Publication date Apr 18, 2024
- HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWE...
- Wolfgang WURST
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
USE OF A SPLIT dCAS FUSION PROTEIN SYSTEM FOR EPIGENETIC EDITING
- Publication number 20240123088
- Publication date Apr 18, 2024
- The Regents of the University of California
- Julian Halmai
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PROTEIN COMPLEX INCLUDING BOTULINUM TOXIN TRANSLOCATION DOMAIN AND...
- Publication number 20240091322
- Publication date Mar 21, 2024
- MVRIX CO., LTD.
- Dae Hyuk KWEON
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED POLYMERASES AND METHODS OF USING THE SAME
- Publication number 20240052325
- Publication date Feb 15, 2024
- DUKE UNIVERSITY
- Lorena S. BEESE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR TARGET RELEASE FROM INTEIN COMPLEXES
- Publication number 20230391821
- Publication date Dec 7, 2023
- Merck Patent GmbH
- Oliver RAMMO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR BIOSYNTHESIS OF PROTEIN HETEROCATENANE
- Publication number 20230348546
- Publication date Nov 2, 2023
- Peking University
- Wenbin ZHANG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CAS9 PROTEINS INCLUDING LIGAND-DEPENDENT INTEINS
- Publication number 20230279443
- Publication date Sep 7, 2023
- President and Fellows of Harvard College
- David R. Liu
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ADENINE BASE EDITORS AND USES THEREOF
- Publication number 20230235309
- Publication date Jul 27, 2023
- THE BROAD INSTITUTE, INC.
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPLIT INTEIN-BASED SELECTION FOR PEPTIDE BINDERS
- Publication number 20230227508
- Publication date Jul 20, 2023
- Massachusetts Institute of Technology
- Christopher A. Voigt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYPEPTIDE CLEAVAGE METHODS
- Publication number 20230159598
- Publication date May 25, 2023
- ABSCI Corporation
- Tyler Nusca
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREPARATION OF HUMAN BASIC FIBROBLAST GROWTH FACTOR BY USING BACILL...
- Publication number 20230151374
- Publication date May 18, 2023
- DREAMTEC INTELLECTUAL PROPERTY LIMITED
- Shu Kun Christopher CHUNG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPLIT INTEINS AND THEIR USES
- Publication number 20230116688
- Publication date Apr 13, 2023
- SPLICEBIO, S.L.
- Silvia FRUTOS DOMÍNGUEZ
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REUSE OF INTEIN-BOUND RESINS FOR PROTEIN PURIFICATION
- Publication number 20230064395
- Publication date Mar 2, 2023
- Merck Patent GmbH
- Oliver RAMMO
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
NANO-PERFORATOR HAVING IMPROVED ANTI-VIRAL ACTIVITY
- Publication number 20220372496
- Publication date Nov 24, 2022
- MVRIX CO., LTD.
- Dae-Hyuk KWEON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUND CHIMERIC ANTIGEN RECEPTOR (cCAR) TARGETING MULTIPLE ANTIGE...
- Publication number 20220348633
- Publication date Nov 3, 2022
- iCell Gene Therapeutics LLC
- Yupo MA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Soluble Intein Fusion Proteins And Methods For Purifying Biomolecules
- Publication number 20220267750
- Publication date Aug 25, 2022
- Merck Patent GmbH
- Martin Zillmann
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PROXIMITY-BASED SORTASE-MEDIATED PROTEIN PURIFICATION AND LIGATION
- Publication number 20220235145
- Publication date Jul 28, 2022
- THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Andrew TSOURKAS
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AAV DELIVERY OF NUCLEOBASE EDITORS
- Publication number 20220213507
- Publication date Jul 7, 2022
- President and Fellows of Harvard College
- David R. Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SPLIT INTEINS, CONJUGATES AND USES THEREOF
- Publication number 20220098293
- Publication date Mar 31, 2022
- The Trustees of Princeton University
- Tom W. Muir
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DIMERIZING AGENT REGULATED IMMUNORECEPTOR COMPLEXES
- Publication number 20220025014
- Publication date Jan 27, 2022
- BLUEBIRD BIO, INC.
- JORDAN JARJOUR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD FOR DETECTING A SPECIFIC SPLICE EVENT OF A GENE OF INTEREST
- Publication number 20210388364
- Publication date Dec 16, 2021
- Helmholtz Zentrum Müncher - Deutsches Forschungszentrum Für Gesundheit Und Um...
- Gil Gregor Westmeyer
- C07 - ORGANIC CHEMISTRY

containing an intein ("protein splicing")domain

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Proximity-based sortase-mediated protein purification and ligation

Protein complex including botulinum toxin translocation domain and...

Split inteins, conjugates and uses thereof

Oncolytic group B adenovirus expressing a stroma-targeted bispecifi...

Split-immunotoxins for boosting oncolytic virus toxicity

Genome editing without nucleases

Soluble intein fusion proteins and methods for purifying biomolecules

Adenovirus armed with bispecific T cell activator

Antigen delivery platforms

CAS9 proteins including ligand-dependent inteins

Bivalent bispecific antibody hybrid protein expression and preparat...

Split intein mediated polymerization and production of mussel foot...

Soluble intein fusion proteins and methods for purifying biomolecules

AAV delivery of nucleobase editors

Proximity-based sortase-mediated protein purification and ligation

Method using split inteins to generate protein conjugates

Split inteins with exceptional splicing activity

Fusion proteins comprising a Mtu ΔI-CM intein variant and methods o...

Chromatography resin, production and use thereof

Split inteins with exceptional splicing activity

Antigen delivery platforms

Methods and compositions for stabilizing trans-splicing intein modi...

Intein-modified proteases, their production and industrial applicat...

Methods and compositions for stabilizing trans-splicing intein modi...

CAS9 proteins including ligand-dependent inteins

Method and system for the production of recombinant proteins by cells

Genome editing without nucleases

Method of using split inteins, conjugates to generate protein conju...

Protein purification using intein-hydrophobin tag and alcohol preci...

Precipitable peptides

Patents Applicationslast 30 patents

ADENOVIRUS ARMED WITH BISPECIFIC T CELL ACTIVATOR

COMPOSITIONS AND METHODS COMPRISING LIPID ASSOCIATED TRANSMEMBRANE...

COMPOSITIONS AND METHODS FOR CELL-BASED DELIVERY SYSTEMS

Recombinant Vectors Comprising Polycistronic Expression Cassettes a...

FUSION PROTEINS COMPRISING AN INTEIN POLYPEPTIDE AND METHODS OF USE...

CHIMERIC ANTIGEN RECEPTOR (CAR)-T CELLS

COMPOSITIONS AND METHODS COMPRISING SPLICING-DERIVED ANTIGENS FOR T...

Adenovirus armed with bispecific T cell activator

PROTEIN PURIFICATION USING A SPLIT INTEIN SYSTEM

CRISPR/CAS9-MEDIATED MEANS AND METHODS FOR CELL REPROGRAMMING

USE OF A SPLIT dCAS FUSION PROTEIN SYSTEM FOR EPIGENETIC EDITING

PROTEIN COMPLEX INCLUDING BOTULINUM TOXIN TRANSLOCATION DOMAIN AND...

ENGINEERED POLYMERASES AND METHODS OF USING THE SAME

METHODS FOR TARGET RELEASE FROM INTEIN COMPLEXES

METHOD FOR BIOSYNTHESIS OF PROTEIN HETEROCATENANE

CAS9 PROTEINS INCLUDING LIGAND-DEPENDENT INTEINS

ADENINE BASE EDITORS AND USES THEREOF

SPLIT INTEIN-BASED SELECTION FOR PEPTIDE BINDERS

POLYPEPTIDE CLEAVAGE METHODS

PREPARATION OF HUMAN BASIC FIBROBLAST GROWTH FACTOR BY USING BACILL...

SPLIT INTEINS AND THEIR USES

REUSE OF INTEIN-BOUND RESINS FOR PROTEIN PURIFICATION

NANO-PERFORATOR HAVING IMPROVED ANTI-VIRAL ACTIVITY

COMPOUND CHIMERIC ANTIGEN RECEPTOR (cCAR) TARGETING MULTIPLE ANTIGE...

Soluble Intein Fusion Proteins And Methods For Purifying Biomolecules

PROXIMITY-BASED SORTASE-MEDIATED PROTEIN PURIFICATION AND LIGATION

AAV DELIVERY OF NUCLEOBASE EDITORS

SPLIT INTEINS, CONJUGATES AND USES THEREOF

DIMERIZING AGENT REGULATED IMMUNORECEPTOR COMPLEXES

METHOD FOR DETECTING A SPECIFIC SPLICE EVENT OF A GENE OF INTEREST