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Stable introduction of foreign DNA into chromosome
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C12N15/90
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C12
Biochemistry
C12N
MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
Current Industry
C12N15/90
Stable introduction of foreign DNA into chromosome
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Patents Grants
last 30 patents
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Patent Grant
Systems, methods, and compositions for correction of frameshift mut...
Patent number
12,146,152
Issue date
Nov 19, 2024
Massachusetts Institute of Technology
Timothy Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Endothelial cell factors and methods thereof
Patent number
12,146,165
Issue date
Nov 19, 2024
THE CHILDREN'S MEDICAL CENTER CORPORATION
Leonard I. Zon
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Generation of induced pluripotent cells by CRISPR activation
Patent number
12,146,166
Issue date
Nov 19, 2024
The J. David Gladstone Institutes
Peng Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Composition for editing a nucleic acid sequence and method using th...
Patent number
12,139,716
Issue date
Nov 12, 2024
Lung-Jr Lin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multiplexed genome editing
Patent number
12,133,515
Issue date
Nov 5, 2024
President and Fellows of Harvard College
George M. Church
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of substituting pathogenic amino acids using programmable b...
Patent number
12,133,884
Issue date
Nov 5, 2024
Beam Therapeutics Inc.
David Bryson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genome editing method
Patent number
12,129,479
Issue date
Oct 29, 2024
SUZHOU QI BIODESIGN BIOTECHNOLOGY COMPANY LIMITED
Caixia Gao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted integration of nucleic acids
Patent number
12,129,480
Issue date
Oct 29, 2024
Genentech, Inc.
Chi Kin Domingos Ng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered adenosine deaminases and base editors thereof
Patent number
12,129,478
Issue date
Oct 29, 2024
Lumiere Therapeutics Co., Ltd.
Bohong Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Haplotype-based treatment of RP1 associated retinal degenerations
Patent number
12,129,496
Issue date
Oct 29, 2024
Massachusetts Eye and Ear Infirmary
Qin Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for modulating a genome
Patent number
12,123,034
Issue date
Oct 22, 2024
FLAGSHIP PIONEERING INNOVATIONS VI, LLC
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR enzyme mutations reducing off-target effects
Patent number
12,123,032
Issue date
Oct 22, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA vectors, transposons and transposases for eukaryotic genome mod...
Patent number
12,122,995
Issue date
Oct 22, 2024
DNA TWOPOINTO INC.
Jeremy Minshull
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,123,015
Issue date
Oct 22, 2024
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Class II, type V CRISPR systems
Patent number
12,123,014
Issue date
Oct 22, 2024
METAGENOMI, INC.
Brian Thomas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleases and compositions, systems, and methods thereof
Patent number
12,123,016
Issue date
Oct 22, 2024
Profluent Bio Inc.
Ali Madani
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Base editing of ANGPTL3 and methods of using same for treatment of...
Patent number
12,115,230
Issue date
Oct 15, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems and methods of assisted reproduction and prevention of gene...
Patent number
12,115,037
Issue date
Oct 15, 2024
Sapphiros AI Bio LLC
Robin Y. Smith
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Optimized protein linkers and methods of use
Patent number
12,110,517
Issue date
Oct 8, 2024
PAIRWISE PLANTS SERVICES, INC.
Sharon Leigh Guffy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR enzymes and systems
Patent number
12,110,490
Issue date
Oct 8, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for genomic integration of nucleic acids i...
Patent number
12,110,498
Issue date
Oct 8, 2024
Amyris, Inc.
Kevin George
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Homology directed repair compositions for the treatment of hemoglob...
Patent number
12,110,499
Issue date
Oct 8, 2024
Seattle Children's Hospital
Andrew Scharenberg
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Universal donor stem cells and related methods
Patent number
12,110,500
Issue date
Oct 8, 2024
President and Fellows of Harvard College
Torsten B. Meissner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
NANOS knock-out that ablates germline cells
Patent number
12,102,069
Issue date
Oct 1, 2024
Washington State University
Jon Michael Oatley
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Storage through iterative DNA editing
Patent number
12,104,167
Issue date
Oct 1, 2024
Microsoft Technology Licensing, LLC
Kris K. Ganjam
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for efficient delivery of therapeutic molecules in vitro an...
Patent number
12,102,691
Issue date
Oct 1, 2024
Massachusetts Eye and Ear Infirmary
Zheng-Yi Chen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for differential Cas9 gene labeling and/or...
Patent number
12,098,381
Issue date
Sep 24, 2024
University of Massachusetts
Thoru Pederson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lentiviral vector and method for delivering exogenous RNA by the le...
Patent number
12,091,674
Issue date
Sep 17, 2024
SHANGHAI BDGENE TECHNOLOGY CO., LTD.
Yujia Cai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Carboxylated nanodiamond-mediated CRISPR-CAS9 delivery system
Patent number
12,091,677
Issue date
Sep 17, 2024
Taipei Veterans General Hospital
Shih-Hwa Chiou
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using programmable DNA binding proteins to enhance targeted genome...
Patent number
12,084,675
Issue date
Sep 10, 2024
Sigma-Aldrich Co. LLC
Fuqiang Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
INHIBITOR OLIGONUCLEOTIDES AND METHODS OF USE THEREOF
Publication number
20240384304
Publication date
Nov 21, 2024
VOR BIOPHARMA INC.
Dane Hazelbaker
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions And Methods For Promoting Gene Editing of CXCR4 Gene
Publication number
20240384306
Publication date
Nov 21, 2024
EmendoBio Inc.
David Baram
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF POLYCYTHEMIA VERA VIA CRISPR/AAV6 GENOME EDITING
Publication number
20240382528
Publication date
Nov 21, 2024
The Board of Trustees of the Leland Stanford Junior University
Matthew H. Porteus
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING NON-AGE-ASSOCIATED HEARING IM...
Publication number
20240384276
Publication date
Nov 21, 2024
Akouos, Inc.
Emmanuel John Simons
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
IDENTIFICATION AND VALIDATION OF GENOMIC SAFE-HARBOR SITES IN SKELE...
Publication number
20240384305
Publication date
Nov 21, 2024
Board of Trustees of the University of Arkansas
Made Harumi Padmaswari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MGAT1 DEFICIENT CELLS AND USES THEREOF
Publication number
20240384320
Publication date
Nov 21, 2024
Rock BioMedical Inc.
Chi-Huey WONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Targeting Nrip1 to Alleviate Metabolic Disease
Publication number
20240384248
Publication date
Nov 21, 2024
University of Massachusetts
Michael P. Czech
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF USHER SYND...
Publication number
20240382620
Publication date
Nov 21, 2024
PRIME MEDICINE, INC.
Wei Hsi Yeh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR MAKING GENETIC EDITS
Publication number
20240381856
Publication date
Nov 21, 2024
Recombinetics, Inc.
Scott C. Fahrenkrug
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
CA S9 EFFECTOR PROTEINS WITH ENHANCED STABILITY
Publication number
20240384246
Publication date
Nov 21, 2024
AstraZeneca AB
GRZEGORZ SIENSKI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Genetically Modified Mycoplasma Bacteria Active Against Heterogenou...
Publication number
20240382537
Publication date
Nov 21, 2024
FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA
Rocco Mazzolini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENOME EDITING METHOD BASED ON CRISPR/CAS9 SYSTEM AND USE THEREOF
Publication number
20240384303
Publication date
Nov 21, 2024
Chungang University Industry Academic Cooperation Foundation
Sang Jun Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED CLASS 2 TYPE V CRISPR SYSTEMS
Publication number
20240376462
Publication date
Nov 14, 2024
Scribe Therapeutics Inc.
Gayathri VIJAYAKUMAR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULAR PRIME EDITING SYSTEMS FOR GENOME ENGINEERING
Publication number
20240376499
Publication date
Nov 14, 2024
University of Massachusetts
Bin Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HOMOLOGY DNA REPAIR ENHANCEMENT OF CAS DERIVATIVES COMPOSITIONS AND...
Publication number
20240374758
Publication date
Nov 14, 2024
TARGETGENE BIOTECHNOLOGIES LTD
Dan Michael WEINTHAL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HYPOIMMUNOGENIC CELL AND METHODS OF GENERATION THEREOF
Publication number
20240376426
Publication date
Nov 14, 2024
Science Corporation
Alan Mardinly
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TYPE I-A CRISPR-CAS3 SYSTEM FOR GENOME EDITING AND DIAGNOSTICS
Publication number
20240376454
Publication date
Nov 14, 2024
Cornell University
Ailong KE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETIC RESISTANCE TO VIRAL DISEASE IN SALMONID FISH
Publication number
20240373829
Publication date
Nov 14, 2024
THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
Ross HOUSTON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NR4A3-DEFICIENT IMMUNE CELLS AND USES THEREOF
Publication number
20240374725
Publication date
Nov 14, 2024
Lyell Immunopharma, Inc.
Viola LAM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULAR GENETICALLY ENGINEERED CELL AND METHODS OF GENERATION THEREOF
Publication number
20240376500
Publication date
Nov 14, 2024
Science Corporation
Alan Mardinly
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND...
Publication number
20240376455
Publication date
Nov 14, 2024
LifeEDIT Therapeutics, Inc.
Gunjan H. Arya
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR IMPROVING GENOME EDITING
Publication number
20240368633
Publication date
Nov 7, 2024
The Regents of the University of California
Valentino GANTZ
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EFFECTOR PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF FOR MANUFA...
Publication number
20240366678
Publication date
Nov 7, 2024
MAMMOTH BIOSCIENCES, INC.
Mark Alan DEWITT
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR CD34 GENE MODIFICATION
Publication number
20240366675
Publication date
Nov 7, 2024
VOR BIOPHARMA INC.
Elizabeth Paik
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA ADENO-ASSOCIATED VIRUS (RAAV) VECTOR AND USES THEREOF
Publication number
20240368629
Publication date
Nov 7, 2024
Huidagene Therapeutics (Singapore) Pte. Ltd.
Linyu Shi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELLS MODIFIED BY A CAS12I POLYPEPTIDE
Publication number
20240368632
Publication date
Nov 7, 2024
Arbor Biotechnologies, Inc.
Tia Marie DiTommaso
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Microfluidic Delivery Method Utilizing An Electric Field
Publication number
20240367172
Publication date
Nov 7, 2024
Indee. Pty. Ltd.
Ryan Pawell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR PRESERVING DEVELOPMENTAL POTENTIAL OF IMMUNE CELLS USED...
Publication number
20240366759
Publication date
Nov 7, 2024
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
Benjamin YOUNGBLOOD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
UNIVERSAL DONOR STEM CELLS AND RELATED METHODS
Publication number
20240368539
Publication date
Nov 7, 2024
President and Fellows of Harvard College
Torsten B. Meissner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions For and Methods of Editing the Genome
Publication number
20240368587
Publication date
Nov 7, 2024
DUKE UNIVERSITY
Dwight Koeberl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...