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Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
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Patents Grants
last 30 patents
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Patent Grant
Methods and compositions for evolving base editors using phage-assi...
Patent number
12,359,218
Issue date
Jul 15, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CPF1 complexes with reduced indel activity
Patent number
12,344,838
Issue date
Jul 1, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleobase editors and uses thereof
Patent number
12,344,869
Issue date
Jul 1, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genetic construct
Patent number
12,319,927
Issue date
Jun 3, 2025
Healing Genes LLC
Michael McDonald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Pterin-dependent biocatalysts and uses thereof
Patent number
12,319,948
Issue date
Jun 3, 2025
Georgia Tech Research Corporation
Pamela Peralta-Yahya
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Deaminases and variants thereof for use in base editing
Patent number
12,312,619
Issue date
May 27, 2025
Accuredit Therapeutics (Suzhou) Co., Ltd.
Feifei Duan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems, methods, and compositions for targeted nucleic acid editing
Patent number
12,297,436
Issue date
May 13, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Base editing enzymes
Patent number
12,286,654
Issue date
Apr 29, 2025
METAGENOMI, INC.
Jyun-Liang Lin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Nucleobase editors comprising GeoCas9 and uses thereof
Patent number
12,281,338
Issue date
Apr 22, 2025
The Broad Institute, Inc.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Small type II-D Cas proteins and methods of use thereof
Patent number
12,252,705
Issue date
Mar 18, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems methods, and compositions for targeted nucleic acid editing
Patent number
12,221,636
Issue date
Feb 11, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cas variants for gene editing
Patent number
12,215,365
Issue date
Feb 4, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chemically modified single-stranded rna-editing oligonucleotides
Patent number
12,203,072
Issue date
Jan 21, 2025
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fusion proteins for improved precision in base editing
Patent number
12,203,077
Issue date
Jan 21, 2025
ShanghaiTech University
Jia Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Polypeptides useful for gene editing and methods of use
Patent number
12,188,018
Issue date
Jan 7, 2025
Life Edit Therapeutics, Inc.
Tyson D. Bowen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of producing nor-opioid and nal-opioid benzylisoquinoline a...
Patent number
12,180,525
Issue date
Dec 31, 2024
Antheia, Inc.
Christina D. Smolke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for detection and measurement of RNA modif...
Patent number
12,173,085
Issue date
Dec 24, 2024
Duke University
Kathryn Meyer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Base editors and uses thereof
Patent number
12,157,760
Issue date
Dec 3, 2024
The Broad Institute, Inc.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered deaminases
Patent number
12,139,732
Issue date
Nov 12, 2024
PIONEER HI-BRED INTERNATIONAL, INC.
Zhenglin Hou
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered adenosine deaminases and base editors thereof
Patent number
12,129,478
Issue date
Oct 29, 2024
Lumiere Therapeutics Co., Ltd.
Bohong Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Optimized protein linkers and methods of use
Patent number
12,110,517
Issue date
Oct 8, 2024
PAIRWISE PLANTS SERVICES, INC.
Sharon Leigh Guffy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Suicide gene therapeutic agent for brain tumors using pluripotent s...
Patent number
12,090,172
Issue date
Sep 17, 2024
Keio University
Masahiro Toda
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Incorporation of unnatural amino acids into proteins using base edi...
Patent number
12,084,663
Issue date
Sep 10, 2024
President and Fellows of Harvard College
Juan Pablo Maianti
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods employing adenosine deaminase-1 (ADA-1) as...
Patent number
12,064,481
Issue date
Aug 20, 2024
Elias El-Haddad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Evolved Cas9 proteins for gene editing
Patent number
12,043,852
Issue date
Jul 23, 2024
President and Fellows of Harvard College
David R. Liu
C07 - ORGANIC CHEMISTRY
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Patent Grant
Photoconjugation reactions for modification of specific proteins on...
Patent number
12,018,081
Issue date
Jun 25, 2024
The Regents of the University of Colorado, a Body Corporate
Andrew P. Goodwin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for treating hemoglobinopathies
Patent number
12,016,908
Issue date
Jun 25, 2024
Beam Therapeutics Inc.
Ian Slaymaker
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems, methods, and compositions for RNA-guided RNA-targeting CRI...
Patent number
12,012,621
Issue date
Jun 18, 2024
Massachusetts Institute of Technology
Omar Abudayyeh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adenosine nucleobase editors and uses thereof
Patent number
11,999,947
Issue date
Jun 4, 2024
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fusion proteins and methods for site-directed genome editing
Patent number
11,976,309
Issue date
May 7, 2024
The Regents of the University of California
Yuxuan Zheng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
ENGINEERED CHIMERIC ISCB POLYPEPTIDES AND USES THEREOF
Publication number
20250236857
Publication date
Jul 24, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CAS VARIANTS FOR GENE EDITING
Publication number
20250236855
Publication date
Jul 24, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING METHODS AND COMPOSITIONS FOR TREATING TRIPLET REPEAT D...
Publication number
20250228981
Publication date
Jul 17, 2025
THE BROAD INSTITUTE, INC.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SAFETY SWITCHES TO CONTROL IN VITRO AND IN VIVO PROLIFERATION OF CE...
Publication number
20250230470
Publication date
Jul 17, 2025
Sana Biotechnology, Inc.
Eleonore THAM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DESIGN AND CONSTRUCTION OF EVOLUTIONARY-GUIDED "SELECTION GENE DRIV...
Publication number
20250228971
Publication date
Jul 17, 2025
The Penn State Research Foundation
Justin Robert PRITCHARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
YEAST EXTRACT WITH FREE GLUTAMATE AND 5'-RIBONUCLEOTIDES
Publication number
20250221439
Publication date
Jul 10, 2025
DSM IP Assets B.V.
Elaheh JAMALZADEH
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Patent Application
COMPOSITIONS AND METHODS FOR TREATING A CONGENITAL EYE DISEASE
Publication number
20250223587
Publication date
Jul 10, 2025
Beam Therapeutics Inc.
David Bryson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES
Publication number
20250223593
Publication date
Jul 10, 2025
ProQR Therapeutics II B.V.
Janne Juha Turunen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEMS METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING
Publication number
20250215408
Publication date
Jul 3, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FUNCTIONAL AAV CAPSIDS FOR SYSTEMIC ADMINISTRATION
Publication number
20250205363
Publication date
Jun 26, 2025
Shape Therapeutics Inc.
Thomas PACKARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TYPE II CAS PROTEINS AND APPLICATIONS THEREOF
Publication number
20250197854
Publication date
Jun 19, 2025
Alia Therapeutics Srl
Antonio Casini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID NANOPARTICLES FOR TARGETED DELIVERY OF MRNA
Publication number
20250195431
Publication date
Jun 19, 2025
Trustees of Tufts College
Qiaobing Xu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-AID USING CATALYTICALLY INACTIVE RNA-GUIDED ENDONUCLEASE
Publication number
20250179528
Publication date
Jun 5, 2025
NOVOZYMES A/S
Takashi Nakanishi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF CYTOTOXIC GENE THERAPY TO TREAT TUMORS
Publication number
20250177494
Publication date
Jun 5, 2025
CANDEL THERAPEUTICS, INC.
Estuardo Aguilar-Cordova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR EDITING SBDS GENE
Publication number
20250179464
Publication date
Jun 5, 2025
The Children's Medical Center Corporation
Christian Brendel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL TYPE VI CRISPR ENZYMES AND SYSTEMS
Publication number
20250171756
Publication date
May 29, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING APPROACHES FOR THE TREATMENT OF BETA-THALASSEMIA
Publication number
20250161492
Publication date
May 22, 2025
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Annarita MICCIO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MUTANT CYTIDINE DEAMINASES WITH IMPROVED EDITING PRECISION
Publication number
20250154490
Publication date
May 15, 2025
CORRECTSEQUENCE THERAPEUTICS
Lijie WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENOSINE DEAMINASE BASE EDITORS AND METHODS FOR USE THEREOF
Publication number
20250144149
Publication date
May 8, 2025
Beam Therapeutics Inc.
Nicole Gaudelli
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS SYSTEMS AND USES THEREOF
Publication number
20250146023
Publication date
May 8, 2025
Lumiere Therapeutics Co., Ltd.
Bohong CHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF
Publication number
20250135036
Publication date
May 1, 2025
WAVE LIFE SCIENCES LTD.
Christopher Michael Acker
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
T CELLS WITH CELL-SURFACE EXPRESSION OF ADENOSINE DEAMINASE AND USE...
Publication number
20250134998
Publication date
May 1, 2025
The Board of Trustees of the Leland Stanford Junior University
Dorota Danuta KLYSZ
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE A...
Publication number
20250137021
Publication date
May 1, 2025
Antheia, Inc.
Christina D. Smolke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CIRCULAR PERMUTANTS, COMPOSITIONS COMPRISING THE SAME, AND METHODS...
Publication number
20250129348
Publication date
Apr 24, 2025
PAIRWISE PLANTS SERVICES, INC.
David Gerhard Schwark
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Methylcytosine-Selective Deaminases and Uses Thereof
Publication number
20250115953
Publication date
Apr 10, 2025
New England Biolabs, Inc.
Laurence Ettwiller
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR REDUCING COMPLEMENT ACTIVATION
Publication number
20250108132
Publication date
Apr 3, 2025
Beam Therapeutics Inc.
Michael S. Packer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
FUSION PROTEINS, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF U...
Publication number
20250109389
Publication date
Apr 3, 2025
PAIRWISE PLANTS SERVICES, INC.
Nathaniel Allen Wesley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
EVOLVED CAS14A1 VARIANTS, COMPOSITIONS, AND METHODS OF MAKING AND U...
Publication number
20250101395
Publication date
Mar 27, 2025
THE BROAD INSTITUTE, INC.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
NOVEL CRISPR ENZYMES AND SYSTEMS
Publication number
20250101400
Publication date
Mar 27, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
MODIFIED REGULATORY T CELLS AND METHODS OF USING THE SAME
Publication number
20250090585
Publication date
Mar 20, 2025
Beam Therapeutics Inc.
Angelica Messana
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE