Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)

Abstract
The present invention relates to nucleic acid molecules such as ribozymes, DNAzymes, and antisense which modulate the synthesis, expression and/or stability of an mRNA encoding one or more receptors of vascular endothelial growth factor, such as flt-1 and KDR. Nucleic acid molecules and methods for the inhibition of angiogenesis and treatment of cancer and ocular diseases are provided, optionally in conjunction with other therapeutic agents.
Description


BACKGROUND OF THE INVENTION

[0002] This invention relates to methods and reagents for the treatment of diseases or conditions relating to the levels of expression of vascular endothelial growth factor (VEGF) receptor(s).


[0003] The following is a discussion of relevant art, none of which is admitted to be prior art to the present invention.


[0004] VEGF, also referred to as vascular permeability factor (VPF) and vasculotropin, is a potent and highly specific mitogen of vascular endothelial cells (for a review see Ferrara, 1993 Trends Cardiovas. Med. 3, 244; Neufeld et al., 1994 Prog. Growth Factor Res. 5, 89). VEGF induced neovascularization is implicated in various pathological conditions such as tumor angiogenesis, proliferative diabetic retinopathy, hypoxia-induced angiogenesis, rheumatoid arthritis, psoriasis, wound healing and others.


[0005] VEGF, an endothelial cell-specific mitogen, is a 34-45 kDa glycoprotein with a wide range of activities that include promotion of angiogenesis, enhancement of vascular-permeability and others. VEGF belongs to the platelet-derived growth factor (PDGF) family of growth factors with approximately 18% homology with the A and B chain of PDGF at the amino acid level. Additionally, VEGF contains the eight conserved cysteine residues common to all growth factors belonging to the PDGF family (Neufeld et al., supra). VEGF protein is believed to exist predominantly as disulfide-linked homodimers; monomers of VEGF have been shown to be inactive (Plouet et al., 1989 EMBO J. 8, 3801).


[0006] VEGF exerts its influence on vascular endothelial cells by binding to specific high-affinity cell surface receptors. Covalent cross-linking experiments with 125lI -labeled VEGF protein have led to the identification of three high molecular weight complexes of 225, 195 and 175 kDa presumed to be VEGF and VEGF receptor complexes (Vaisman et al., 1990 J. Biol. Chem. 265, 19461). Based on these studies VEGF-specific receptors of 180, 150 and 130 kDa molecular mass were predicted. In endothelial cells, receptors of 150 and the 130 kDa have been identified. The VEGF receptors belong to the superfamily of receptor tyrosine kinases (RTKs) characterized by a conserved cytoplasmic catalytic kinase domain and a hydrophylic kinase sequence. The extracellular domains of the VEGF receptors consist of seven immunoglobulin-like domains that are thought to be involved in VEGF binding functions.


[0007] The two most abundant and high-affinity receptors of VEGF are flt-1 (fms-like tyrosine kinase) cloned by Shibuya et al., 1990 Oncogene 5, 519 and KDR (kinase-insert-domain-containing receptor) cloned by Terman et al., 1991 Oncogene 6, 1677. The murine homolog of KDR, cloned by Mathews et al., 1991, Proc. Natl. Acad. Sci., USA, 88, 9026, shares 85% amino acid homology with KDR and is termed as flk-1 (fetal liver kinase-1). Recently it has been shown that the high-affinity binding of VEGF to its receptors is modulated by cell surface-associated heparin and heparin-like molecules (Gitay-Goren et al., 1992 J. Biol. Chem. 267, 6093).


[0008] VEGF expression has been associated with several pathological states such as tumor angiogenesis, several forms of blindness, rheumatoid arthritis, psoriasis and others. Following is a brief summary of evidence supporting the involvement of VEGF in various diseases:


[0009] 1) Tumor angiogenesis: Increased levels of VEGF gene expression have been reported in vascularized and edema-associated brain tumors (Berkman et al., 1993 J. Clini. Invest. 91, 153). A more direct demostration of the role of VEGF in tumor angiogenesis was demonstrated by Jim Kim et al., 1993 Nature 362,841 wherein, monoclonal antibodies against VEGF were successfully used to inhibit the growth of rhabdomyosarcoma, glioblastoma multiforme cells in nude mice. Similarly, expression of a dominant negative mutated form of the flt-1 VEGF receptor inhibits vascularization induced by human glioblastoma cells in nude mice (Millauer et al., 1994, Nature 367, 576).


[0010] 2) Ocular diseases: Aiello et al., 1994 New Engl. J. Med. 331, 1480, showed that the ocular fluid of a majority of patients suffering from diabetic retinopathy and other retinal disorders, contains a high concentration of VEGF. Miller et al., 1994 Am. J. Pathol. 145, 574, reported elevated levels of VEGF mRNA in patients suffering from retinal ischemia. These observations support a direct role for VEGF in ocular diseases.


[0011] 3) Psoriasis: Detmar et al., 1994 J. Exp. Med. 180, 1141 reported that VEGF and its receptors were over-expressed in psoriatic skin and psoriatic dermal microvessels, suggesting that VEGF plays a significant role in psoriasis.


[0012] 4) Rheumatoid arthritis: Immunohistochemistry and in situ hybridization studies on tissues from the joints of patients suffering from rheumatoid arthritis show an increased level of VEGF and its receptors (Fava et al., 1994 J. Exp. Med. 180, 341). Additionally, Koch et al., 1994 J. Immunol. 152, 4149, found that VEGF-specific antibodies were able to significantly reduce the mitogenic activity of synovial tissues from patients suffering from rheumatoid arthritis. These observations support a direct role for VEGF in rheumatoid arthritis.


[0013] In addition to the above data on pathological conditions involving excessive angiogenesis, a number of studies have demonstrated that VEGF is both necessary and sufficient for neovascularization. Takashita et al., 1995 J. Clin. Invest. 93, 662, demonstrated that a single injection of VEGF augmented collateral vessel development in a rabbit model of ischemia. VEGF also can induce neovascularization when injected into the cornea. Expression of the VEGF gene in CHO cells is sufficient to confer tumorigenic potential to the cells. Kim et al., supra and Millauer et al., supra used monoclonal antibodies against VEGF or a dominant negative form of flk-1 receptor to inhibit tumor-induced neovascularization.


[0014] During development, VEGF and its receptors are associated with regions of new vascular growth (Millauer et al., 1993 Cell 72, 835; Shalaby et al., 1993 J. Clin. Invest. 91, 2235). Furthermore, transgenic mice lacking either of the VEGF receptors are defective in blood vessel formation, in fact these mice do not survive; flk-1 appears to be required for differentiation of endothelial cells, while flt-1 appears to be required at later stages of vessel formation (Shalaby et al., 1995 Nature 376, 62; Fung et al., 1995 Nature 376, 66). Thus, these receptors must be present to properly signal endothelial cells or their precursors to respond to vascularization-promoting stimuli.


[0015] All of the conditions listed above, involve extensive vascularization. This hyper-stimulation of endothelial cells may be alleviated by VEGF antagonists. Thus most of the therapeutic efforts for the above conditions have concentrated on finding inhibitors of the VEGF protein.


[0016] Kim et al., 1993 Nature 362, 841 have been successful in inhibiting VEGF-induced tumor growth and angiogenesis in nude mice by treating the mice with VEGF-specific monoclonal antibody.


[0017] Koch et al., 1994 J. Immunol. 152, 4149 showed that the mitogenic activity of microvascular endothelial cells found in rheumatoid arthritis (RA) synovial tissue explants and the chemotactic property of endothelial cells from RA synovial fluid can be neutralized significantly by treatment with VEGF-specific antibodies.


[0018] Ullrich et al., International PCT Publication No. WO 94/11499 and Millauer et al., 1994 Nature 367, 576 used a soluble form of flk-1 receptor (dominant-negative mutant) to prevent VEGF-mediated tumor angiogenesis in immunodeficient mice.


[0019] Kendall and Thomas, International PCT Publication No. WO 94/21679 describe the use of naturally occuring or recombinantly-engineered soluble forms of VEGF receptors to inhibit VEGF activity.


[0020] Robinson, International PCT Publication No. WO 95/04142 describes the use of antisense oligonucleotides targeted against VEGF RNA to inhibit VEGF expression.


[0021] Jellinek et al., 1994 Biochemistry 33, 10450 describe the use of VEGF-specific high-affinity RNA aptamers to inhibit the binding of VEGF to its receptors.


[0022] Rockwell and Goldstein, International PCT Publication No. WO 95/21868, describe the use of anti-VEGF receptor monoclonal antibodies to neutralize the effect of VEGF on endothelial cells.



SUMMARY OF THE INVENTION

[0023] The invention features novel nucleic acid-based compounds [e.g., enzymatic nucleic acid molecules (ribozymes such as Inozyme, G-cleaver, amberzyme, zinzyme), DNAzyme, antisense nucleic acids, 2-5A antisense chimeras, triplex forming nucleic acid, decoy nucleic acids, aptamers, allozymes, antisense nucleic acids containing RNA cleaving chemical groups (Cook et al., U.S. Pat. No. 5,359,051)] and methods for their use to down regulate or inhibit the expression of receptors of VEGF (VEGF-R).


[0024] In one embodiment, the invention features the use of one or more of the nucleic acid-based compounds to inhibit the expression of flt-1 and/or flk-1/KDR receptors.


[0025] In another embodiment, the present invention features a compound having Formula I: (SEQ ID NO: 20818).


[0026] 5′ gsasgsusugcUGAuGagg ccgaaa ggccGaaAgucugB 3′


[0027] wherein each a is 2′-O-methyl adenosine nucleotide, each g is a 2′-O-methyl guanosine nucleotide, each c is a 2′-O-methyl cytidine nucleotide, each u is a 2′-O-methyl uridine nucleotide, each A is adenosine, each G is guanosine, each s individually represents a phosphorothioate internucleotide linkage, U is 2′-deoxy-2′-C-allyl uridine, and B is an inverted deoxyabasic moiety.


[0028] In another embodiment, the present invention features a compound having Formula II: (SEQ ID NO: 13488).


[0029] 5′-usascs asau ucU GAu Gag gcg aaa gcc Gaa Aag aca aB-3′


[0030] wherein each a is 2′-O-methyl adenosine nucleotide, each g is a 2′-O-methyl guanosine nucleotide, each c is a 2′-O-methyl cytidine nucleotide, each u is a 2′-O-methyl uridine nucleotide, each A is adenosine, each G is guanosine, each s individually represents a phosphorothioate internucleotide linkage, U is 2′-deoxy-2′-C-allyl uridine, and B is an inverted deoxyabasic moiety.


[0031] In one embodiment, the invention features a composition comprising a compound of Formula I and/or II in a pharmaceutically acceptable carrier or diluent.


[0032] In another embodiment, the invention features a method of administering to a cell, for example a mammalian cell or human cell, the compound of Formula I and/or II, comprising contacting the cell with the compound under conditions suitable for administration, for example in the presence of a delivery reagent. Examples of suitable delivery reagents include a lipid, cationic lipid, phospholipid, or liposome as described herein and known in the art.


[0033] In one embodiment, the invention features a method of administering to a cell the compound of Formula I or II in conjunction with a chemotherapeutic agent comprising contacting the cell with the compound and the chemotherapeutic agent under conditions suitable for administration.


[0034] Examples of chemotherapeutic agents that can be combined with the compound of Formula I and/or II include but are not limited to 5-fluoro uridine, Leucovorin, Irinotecan (CAMPTOSAR® or CPT-11 or Camptothecin-11 or Campto), Paclitaxel, or Carboplatin or a combination thereof.


[0035] In another embodiment, the present invention also features a cell comprising the compound of Formula I and/or II, wherein the cell is a mammalian cell. For example, in one embodiment the mammalian cell is a human cell.


[0036] In one embodiment, the invention features a method of inhibiting angiogenesis, for example tumor angiogenesis, in a patient comprising the step of contacting the patient with the compound of Formula I and/or II under conditions suitable for said inhibition. In one embodiment, the patient is a mammal, for example, a human.


[0037] In another embodiment, the invention features a method of treatment of a patient having a condition associated with an increased level of VEGF receptor, for example, cancers such as breast cancer, lung cancer, colorectal cancer, renal cancer, pancreatic cancer, or melanoma, or ocular indications such as diabetic retinopathy, or age related macular degeneration, comprising contacting one or more cells of the patient with the compound of Formula I and/or II, under conditions suitable for the treatment. In one embodiment, the patient is a human.


[0038] In another embodiment, the invention features a method of treatment of a patient having an ocular condition associated with an increased level of a VEGF receptor, for example, diabetic retinopathy, or age related macular degeneration, comprising contacting one or more cells of the patient with a nucleic acid molecule, such as an enzymatic nucleic acid molecule, targeted against a VEGF receptor RNA, e.g., a molecule according to Formula I and/or II, under conditions suitable for the treatment. In one embodiment, the patient is a human.


[0039] In yet another embodiment, a method of treatment of the invention further comprises the use of one or more drug therapies under conditions suitable for the treatment.


[0040] In one embodiment, the present invention also features a method of cleaving RNA comprising a sequence of flt-1 comprising contacting the compound of Formula I with the RNA under conditions suitable for the cleavage of the RNA, for example, where the cleavage is carried out in the presence of a divalent cation such as Mg2+.


[0041] In another embodiment, the invention features a method of administering to a mammal, for example a human, the compound of Formula I and/or II comprising contacting the mammal with the compound under conditions suitable for the administration, for example, in the presence of a delivery reagent such as a lipid, cationic lipid, phospholipid, or liposome.


[0042] In yet another embodiment, the invention features a method of administering to a mammal the compound of Formula I and/or II in conjunction with a chemotherapeutic agent comprising contacting the mammal, for example a human, with the compound and the chemotherapeutic agent under conditions suitable for the administration.


[0043] In another embodiment, the invention features a composition comprising the nucleic acid molecule of the instant invention and a pharmaceutically acceptable carrier or diluent.


[0044] By “inhibit” it is meant that the activity of VEGF-R or level of VEGF-R mRNAs or equivalent RNAs encoding VEGF-R is reduced below that observed in the absence of a nucleic acid molecule of the instant invention. In one embodiment, inhibition with enzymatic nucleic acid preferably is below that level observed in the presence of an enzymatically inactive or attenuated molecule that is able to bind to the same site on the mRNA, but is unable to cleave that RNA. In another embodiment, inhibition with antisense oligonucleotides is preferably below that level observed in the presence of, for example, an oligonucleotide with scrambled sequence or with mismatches. In another embodiment, inhibition of a VEGF-R gene with the nucleic acid molecule of the instant invention is greater in the presence of the nucleic acid molecule than in its absence.


[0045] By “enzymatic nucleic acid molecule” it is meant an RNA molecule which has complementarity in a substrate binding region to a specified gene target, and also has an enzymatic activity which is active to specifically cleave target RNA. That is, the enzymatic RNA molecule is able to intermolecularly cleave RNA and thereby inactivate a target RNA molecule. The complementary region(s) allows sufficient hybridization of the enzymatic RNA molecule to the target RNA and thus permit cleavage. One hundred percent complementarity is preferred, but complementarity as low as 50-75% can also be useful in this invention. The nucleic acids can be modified at the base, sugar, and/or phosphate groups. The term enzymatic nucleic acid is used interchangeably with phrases such as ribozymes, catalytic RNA, enzymatic RNA, enzymatic DNA, catalytic DNA, catalytic oligonucleotides, nucleozyme, DNAzyme, Zinzyme, RNA enzyme, endoribonuclease, endonuclease, minizyme, leadzyme, oligozyme or DNA enzyme. All of these terminologies describe nucleic acid molecules with enzymatic activity. The specific enzymatic nucleic acid molecules described in the instant application are not meant to be limiting and those skilled in the art will recognize that all that is important in an enzymatic nucleic acid molecule of this invention is that it have a specific substrate binding site which is complementary to one or more of the target nucleic acid regions, and that it have nucleotide sequences within or surrounding that substrate binding site which impart a nucleic acid cleaving activity to the molecule (Cech et al., U.S. Pat. No. 4,987,071; Cech et al., 1988, JAMA).


[0046] By “enzymatic portion” or “catalytic domain” is meant that portion/region of the enzymatic nucleic acid essential for cleavage of a nucleic acid substrate (for example see FIG. 1).


[0047] By “substrate binding arm” or “substrate binding domain” is meant that portion/region of a enzymatic nucleic acid which is complementary to (i.e., able to base-pair with) a portion of its substrate. Generally, such complementarity is 100%, but can be less if desired. For example, as few as 10 bases out of 14 can be base-paired. Such arms are shown generally in FIG. 1. That is, these arms contain sequences within an enzymatic nucleic acid are intended to bring enzymatic nucleic acid and target RNA together through complementary base-pairing interactions. The enzymatic nucleic acid of the invention can have binding arms that are contiguous or non-contiguous and can be of varying lengths. The length of the binding arm(s) are preferably greater than or equal to four nucleotides, and are of sufficient length to stably interact with the target RNA; specifically 12-100 nucleotides; more specifically 14-24 nucleotides long. If two binding arms are chosen, the design is such that the length of the binding arms are symmetrical (i.e., each of the binding arms is of the same length; e.g., five and five nucleotides, six and six nucleotides or seven and seven nucleotides long) or asymmetrical (i.e., the binding arms are of different length; e.g., six and three nucleotides; three and six nucleotides long; four and five nucleotides long; four and six nucleotides long; four and seven nucleotides long; and the like).


[0048] By “DNAzyme” is meant an enzymatic nucleic acid molecule lacking a 2′-OH group. In particular embodiments, the enzymatic nucleic acid molecule can have an attached linker(s) or other attached or associated groups, moieties, or chains containing one or more nucleotides with 2′-OH groups.


[0049] By “zinzyme” motif or configuration is meant a class II enzymatic nucleic acid molecule comprising a motif as generally described in FIG. 32 and in Beigelman et al., International PCT publication No. WO 99/55857 and U.S. patent application Ser. No. 09/918,728, which is herein incorporated by reference in its entirety, including the drawings. Zinzymes possess endonuclease activity to cleave RNA substrates having a cleavage triplet including but not limited to, YG/Y, where Y is uridine or cytidine, and G is guanosine and/represents the cleavage site. Zinzymes can be chemically modified to increase nuclease stability through various substitutions, including substituting 2′-O-methyl guanosine nucleotides for guanosine nucleotides. In addition, differing nucleotide and/or non-nucleotide linkers can be used to substitute the 5′-gaaa-2′ loop of the motif. Zinzymes represent a non-limiting example of an enzymatic nucleic acid molecule that does not require a ribonucleotide (2′-OH) group within its own nucleic acid sequence for activity.


[0050] By “sufficient length” is meant a nucleic acid molecule long enough to provide the intended function under the expected condition. For example, a nucleic acid molecule of the invention needs to be of “sufficient length” to provide stable binding to a target site under the expected binding conditions and environment. In another non-limiting example, for the binding arms of an enzymatic nucleic acid, “sufficient length” means that the binding arm sequence is long enough to provide stable binding to a target site under the expected reaction conditions and environment. The binding arms are not so long as to prevent useful turnover of the nucleic acid molecule.


[0051] By “stably interact” is meant interaction of the oligonucleotides with target, such as a target protein or target nucleic acid (e.g., by forming hydrogen bonds with complementary amino acids or nucleotides in the target under physiological conditions) that is sufficient for the intended purpose (e.g., specific binding to a protein target to disrupt the function of that protein or cleavage of target RNA/DNA by an enzyme).


[0052] By “equivalent” RNA to VEGF-R is meant to include those naturally occurring RNA molecules having homology (partial or complete) to VEGF-R, or encoding for proteins with similar function as VEGF-R in various animals, including human, rodent, primate, rabbit and pig. The equivalent RNA sequence also includes in addition to the coding region, regions such as 5′untranslated region, 3′-untranslated region, introns, intron-exon junction and the like.


[0053] By “homology” is meant the nucleotide sequence of two or more nucleic acid molecules is partially or completely identical.


[0054] By “antisense nucleic acid” it is meant a non-enzymatic nucleic acid molecule that binds to target RNA by means of RNA-RNA or RNA-DNA or RNA-PNA (protein nucleic acid; Egholm et al., 1993 Nature 365, 566) interactions and alters the activity of the target RNA (for a review see Stein and Cheng, 1993 Science 261, 1004). Typically, antisense molecules will be complementary to a target sequence along a single contiguous sequence of the antisense molecule. However, in certain embodiments, an antisense molecule may bind to substrate such that the substrate molecule forms a loop, and/or an antisense molecule may bind such that the antisense molecule forms a loop. Thus, the antisense molecule may be complementary to two (or even more) non-contiguous substrate sequences or two (or even more) non-contiguous sequence portions of an antisense molecule may be complementary to a target sequence or both.


[0055] By “2-5A antisense chimera” it is meant, an antisense oligonucleotide containing a 5′ phosphorylated 2′-5′-linked adenylate residues. These chimeras bind to target RNA in a sequence-specific manner and activate a cellular 2-5A-dependent ribonuclease which, in turn, cleaves the target RNA (Torrence et al., 1993 Proc. Natl. Acad. Sci. USA 90, 1300).


[0056] By “triplex DNA” it is meant an oligonucleotide that can bind to a double-stranded DNA in a sequence-specific manner to form a triple-strand helix. Formation of such triple helix structure has been shown to inhibit transcription of the targeted gene (Duval-Valentin et al., 1992 Proc. Natl. Acad. Sci. USA 89, 504).


[0057] By “gene” it is meant a nucleic acid that encodes an RNA, for example, nucleic acid sequences including, but not limited to, structural genes encoding a polypeptide.


[0058] By “complementarity” is meant that a nucleic acid can form hydrogen bond(s) with another nucleic acid sequence by either traditional Watson-Crick or other non-traditional types. In reference to the nucleic molecules of the present invention, the binding free energy for a nucleic acid molecule with its target or complementary sequence is sufficient to allow the relevant function of the nucleic acid to proceed, e.g., ribozyme cleavage, antisense or triple helix inhibition. Determination of binding free energies for nucleic acid molecules is well known in the art (see, e.g., Turner et al., 1987, CSH Symp. Quant. Biol. LII pp. 123-133; Frier et al., 1986, Proc. Nat. Acad. Sci. USA 83:9373-9377; Turner et al., 1987, J. Am. Chem. Soc. 109:3783-3785. A percent complementarity indicates the percentage of contiguous residues in a nucleic acid molecule which can form hydrogen bonds (e.g., Watson-Crick base pairing) with a second nucleic acid sequence (e.g., 5, 6, 7, 8, 9, 10 out of 10 being 50%, 60%, 70%, 80%, 90%, and 100% complementary). “Perfectly complementary” means that all the contiguous residues of a nucleic acid sequence will hydrogen bond with the same number of contiguous residues in a second nucleic acid sequence.


[0059] Seven basic varieties of naturally-occurring enzymatic RNAs are known presently. Each can catalyze the hydrolysis of RNA phosphodiester bonds in trans (and thus can cleave other RNA molecules) under physiological conditions. Table I summarizes some of the characteristics of these ribozymes. In general, enzymatic nucleic acids act by first binding to a target RNA. Such binding occurs through the target binding portion of a enzymatic nucleic acid which is held in close proximity to an enzymatic portion of the molecule that acts to cleave the target RNA. Thus, the enzymatic nucleic acid first recognizes and then binds a target RNA through complementary base-pairing, and once bound to the correct site, acts enzymatically to cut the target RNA. Strategic cleavage of such a target RNA destroys its ability to direct synthesis of an encoded protein. After an enzymatic nucleic acid has bound and cleaved its RNA target, it is released from that RNA to search for another target and can repeatedly bind and cleave new targets. Thus, a single enzymatic nucleic acid molecule is able to cleave many molecules of target RNA. In addition, the enzymatic nucleic acid is a highly specific inhibitor of gene expression, with the specificity of inhibition depending not only on the base-pairing mechanism of binding to the target RNA, but also on the mechanism of target RNA cleavage. Single mismatches, or base-substitutions, near the site of cleavage can completely eliminate catalytic activity of a ribozyme.


[0060] Enzymatic nucleic acids that cleave the specified sites in VEGF-R mRNAs represent a novel therapeutic approach to treat tumor angiogenesis, and cancers including, but not limited to, tumor and cancer types shown under Diagnosis in Table XX, ocular diseases, rhuematoid arthritis, psoriasis and others. The enzymatic nucleic acid molecules of the instant invention are able to inhibit the activity of VEGF-R (specifically flt-1 and flk-1/KDR) and the catalytic activity of the enzymatic nucleic acid molecules is required for their inhibitory effect. Those of ordinary skill in the art will find it clear from the exemplary nucleic acid molecules described that other enzymatic nucleic acid molecules that cleave VEGF-R mRNAs can be readily designed and are within the scope of the invention.


[0061] In one of the embodiments of the inventions described herein, the enzymatic nucleic acid molecule is formed in a hammerhead or hairpin motif, but can also be formed in the motif of a hepatitis delta virus, group I intron, group II intron or RNase P RNA (in association with an RNA guide sequence), Neurospora VS RNA, DNAzymes, Zinzymes, NCH cleaving motifs, or G-cleavers. Examples of such hammerhead motifs are described by Dreyfus, supra, Rossi et al., 1992, AIDS Research and Human Retroviruses 8, 183; of hairpin motifs by Hampel et al., EP0360257, Hampel and Tritz, 1989 Biochemistry 28, 4929, Feldstein et al., 1989, Gene 82, 53, Haseloff and Gerlach, 1989, Gene, 82, 43, and Hampel et al., 1990 Nucleic Acids Res. 18, 299; Chowrira & McSwiggen, U.S. Pat. No. 5,631,359; of the hepatitis delta virus motif is described by Perrotta and Been, 1992 Biochemistry 31, 16; of the RNase P motif by Guerrier-Takada et al., 1983 Cell 35, 849; Forster and Altman, 1990, Science 249, 783; Li and Altman, 1996, Nucleic Acids Res. 24, 835; Neurospora VS RNA ribozyme motif is described by Collins (Saville and Collins, 1990 Cell 61, 685-696; Saville and Collins, 1991 Proc. Natl. Acad. Sci. USA 88, 8826-8830; Collins and Olive, 1993 Biochemistry 32, 2795-2799; Guo and Collins, 1995, EMBO. J. 14, 363); Group II introns are described by Griffin et al., 1995, Chem. Biol. 2, 761; Michels and Pyle, 1995, Biochemistry 34, 2965; Pyle et al., International PCT Publication No. WO 96/22689; of the Group I intron by Cech et al., U.S. Pat. No. 4,987,071; of Zinzymes as is generally described by Beigelman et al., International PCT publication No. WO 99/55857 (see for example FIG. 32); and of DNAzymes as is generally described by Usman et al., International PCT Publication No. WO 95/11304; Chartrand et al., 1995, NAR 23, 4092; Breaker et al., 1995, Chem. Bio. 2, 655; Santoro et al., 1997, PNAS 94, 4262 (see for example FIG. 33). NCH cleaving motifs are described in Ludwig & Sproat, International PCT Publication No. WO 98/58058; and G-cleavers are described in Kore et al., 1998, Nucleic Acids Research 26, 4116-4120 and Eckstein et al., International PCT Publication No. WO 99/16871. These specific motifs are not limiting in the invention and those skilled in the art will recognize that all that is important in an enzymatic nucleic acid molecule of this invention is that it has a specific substrate binding site which is complementary to one or more of the target gene RNA regions, and that it have nucleotide sequences within or surrounding that substrate binding site which impart an RNA cleaving activity to the molecule (Cech et al., U.S. Pat. No. 4,987,071).


[0062] Enzymatic nucleic acid molecules of the invention that are allosterically regulated (“allozymes”) can be used to modulate VEGR receptor expression. These allosteric enzymatic nucleic acids or allozymes (see for example George et al., U.S. Pat. Nos. 5,834,186 and 5,741,679, Shih et al., U.S. Pat. No. 5,589,332, Nathan et al., U.S. Pat. No. 5,871,914, Nathan and Ellington, International PCT publication No. WO 00/24931, Breaker et al., International PCT Publication Nos. WO 00/26226 and 98/27104, and Sullenger et al., International PCT publication No. WO 99/29842) are designed to respond to a signaling agent. For example, allozymes can be designed to respond to signaling agents, such as flt-1 or kdr protein, flt-1 or kdr RNA, other proteins and/or RNAs involved in VEGF activity, and also, for example, compounds, metals, polymers, molecules and/or drugs that are targeted to VEGF or VEGF receptor, such as flt-1 or kdr expressing cells etc., which in turn modulate the activity of the enzymatic nucleic acid molecule. In response to interaction with a predetermined signaling agent, the activity of the allosteric enzymatic nucleic acid molecule is activated or inhibited such that the expression of a particular target is selectively down-regulated. The target can comprise flt-1 or kdr and/or a predetermined cellular component or receptor that modulates VEGF activity.


[0063] In a specific example, allosteric enzymatic nucleic acid molecules that are activated by interaction with a RNA encoding a flt-1 protein are used as therapeutic agents in vivo. The presence of RNA encoding the flt-1 protein activates the allosteric enzymatic nucleic acid molecule that subsequently cleaves the RNA encoding the fit-1 protein, resulting in the inhibition of flt-1 protein expression. In this manner, cells that express the flt-1 protein are selectively targeted.


[0064] In another non-limiting example, an allozyme can be activated by an flt-1 protein or peptide that caused the allozyme to inhibit the expression of flt-1 gene by, for example, cleaving RNA encoded by flt-1 gene. In this non-limiting example, the allozyme acts as a decoy to inhibit the function of flt-1 and also inhibit the expression of flt-1 once activated by the flt-1 protein.


[0065] In one embodiment, the nucleic acid molecule of the invention, e.g., antisense molecule, triplex DNA, or ribozyme, is 13 to 100 nucleotides in length, e.g., in specific embodiments 35, 36, 37, or 38 nucleotides in length (e.g., for particular ribozymes). In particular embodiments, the nucleic acid molecule is 15-100, 17-100, 20-100, 21-100, 23-100, 25-100, 27-100, 30-100, 32-100, 35-100, 40-100, 50-100, 60-100, 70-100, or 80-100 nucleotides in length. Instead of 100 nucleotides being the upper limit on the length ranges specified above, the upper limit of the length range can be, for example, 30, 40, 50, 60, 70, or 80 nucleotides. Thus, for any of the length ranges, the length range for particular embodiments has a lower limit as specified, with an upper limit as specified which is greater than the lower limit. For example, in a particular embodiment, the length range can be 35-50 nucleotides in length. All such ranges are expressly included. Also in particular embodiments, a nucleic acid molecule can have a length which is any of the lengths specified above, for example, 21 nucleotides in length.


[0066] In one embodiment, the invention provides a method for producing a class of enzymatic cleaving agents which exhibit a high degree of specificity for the RNA of a desired target. The enzymatic nucleic acid molecule is preferably targeted to a highly conserved sequence region of target mRNAs encoding VEGF-R proteins (specifically flt-1 and flk-1/KDR) such that specific treatment of a disease or condition can be provided with either one or several enzymatic nucleic acids. Such enzymatic nucleic acid molecules can be delivered exogenously to specific tissue or cellular targets as required. Alternatively, the enzymatic nucleic acid molecules can be expressed from DNA and/or RNA vectors that are delivered to specific cells.


[0067] By “highly conserved sequence region” is meant a nucleotide sequence of one or more regions in a nucleic acid molecule that does not vary significantly from one generation to the other or from one biological system to the other.


[0068] Synthesis of nucleic acids greater than 100 nucleotides in length is difficult using automated methods, and the therapeutic cost of such molecules is prohibitive. In this invention, small nucleic acid motifs (e.g., antisense oligonucleotides, hammerhead or the hairpin ribozymes) are used for exogenous delivery. The simple structure of these molecules increases the ability of the nucleic acid to invade targeted regions of the mRNA structure. However, these nucleic acid molecules can also be expressed within cells from eukaryotic promoters (e.g., Izant and Weintraub, 1985 Science 229, 345; McGarry and Lindquist, 1986 Proc. Natl. Acad. Sci. USA 83, 399; SullengerScanlon et al., 1991, Proc. Natl. Acad. Sci. USA, 88, 10591-5; Kashani-Sabet et al., 1992 Antisense Res. Dev., 2, 3-15; Dropulic et al., 1992 J. Virol, 66, 1432-41; Weerasinghe et al., 1991 J. Virol, 65, 5531-4; Ojwang et al., 1992 Proc. Natl. Acad. Sci. USA 89, 10802-6; Chen et al., 1992 Nucleic Acids Res., 20, 4581-9; Sarver et al., 1990 Science 247, 1222-1225; Thompson et al., 1995 Nucleic Acids Res. 23, 2259). Those skilled in the art realize that any nucleic acid can be expressed in eukaryotic cells from the appropriate DNA/RNA vector. The activity of such nucleic acids can be augmented by their release from the primary transcript by a ribozyme (Draper et al., PCT WO93/23569, and Sullivan et al., PCT WO94/02595, both hereby incorporated in their totality by reference herein; Ohkawa et al., 1992 Nucleic Acids Symp. Ser., 27, 15-6; Taira et al., 1991, Nucleic Acids Res., 19, 5125-30; Ventura et al., 1993 Nucleic Acids Res., 21, 3249-55; Chowrira et al., 1994 J. Biol. Chem. 269, 25856).


[0069] The nucleic acid molecules of the invention are useful for the prevention of diseases and conditions related to the level of VEGF-R, including cancer (including but not limited to tumor and cancer types shown under Diagnosis in Table XX), diabetic retinopathy, macular degeneration, neovascular glaucoma, myopic degeneration, arthritis, psoriasis, verruca vulgaris, angiofibroma of tuberous sclerosis, pot-wine stains, Sturge Weber syndrome, Kippel-Trenaunay-Weber syndrome, Osler-Weber-Rendu syndrome and any other diseases or conditions that are related to the levels of VEGF-R (specifically flt-1 and flk-1/KDR) in a cell or tissue.


[0070] By “diseases or conditions related to the level of VEGF-R” is meant that the reduction of VEGF-R (specifically flt-1 and flk-1/KDR) RNA levels and thus reduction in the level of the respective protein will relieve, to some extent, the symptoms of the disease or condition.


[0071] Nucleic acid molecules of the invention are added directly, or can be complexed with cationic lipids, packaged within liposomes, or otherwise delivered to target cells or tissues. The nucleic acid or nucleic acid complexes can be locally administered to relevant tissues ex vivo, or in vivo through injection, infusion pump or stent, with or without their incorporation in biopolymers.


[0072] In one embodiment, the enzymatic nucleic acid molecule of the invention has one or more binding arms which are complementary to the substrate sequences in Tables II to IX, XIV-XIX, XXII, and XXIII. Examples of such enzymatic nucleic acid molecules also are shown in Tables II to IX, XIV-XIX, XXII, and XXIII. Examples of such enzymatic nucleic acid molecules consist essentially of sequences defined in these Tables.


[0073] In yet another embodiment, the invention features antisense nucleic acid molecules and 2-5A chimera including sequences complementary to the target sequences shown in Tables II to IX, XIV-XIX, XXII, and XXIII. Such nucleic acid molecules can include sequences as shown for the binding arms of the enzymatic nucleic acid molecules in Tables II to IX, XIV-XIX, XXII, and XXIII. Similarly, triplex molecules can be provided targeted to the corresponding DNA target regions, and containing the DNA equivalent of a target sequence or a sequence complementary to the specified target (substrate) sequence. Typically, antisense molecules are complementary to a target sequence along a single contiguous sequence of the antisense molecule. However, in certain embodiments, an antisense molecule can bind to substrate such that the substrate molecule forms a loop, and/or an antisense molecule can bind such that the antisense molecule forms a loop. Thus, the antisense molecule can be complementary to two (or even more) non-contiguous substrate sequences or two (or even more) non-contiguous sequence portions of an antisense molecule can be complementary to a target sequence or both.


[0074] By “consists essentially of” is meant that the active nucleic acid molecule of the invention, for example, an enzymatic nucleic acid molecule, contains an enzymatic center or core equivalent to those in the examples, and binding arms able to bind RNA such that cleavage at the target site occurs. Other sequences can be present that do not interfere with such cleavage. Thus, a core region can, for example, include one or more loop, stem-loop structure, or linker that does not prevent enzymatic activity. Thus, the underlined regions in the sequences in Tables II, IV, VI, VIII, XIV and XVI can be such a loop, stem-loop, nucleotide linker, and/or non-nucleotide linker and can be represented generally as sequence “X”. For example, a core sequence for a hammerhead enzymatic nucleic acid can comprise a conserved sequence, such as 5′-CUGAUGAG-3′ and 5′-CGAA-3′ connected by “X”, where X is 5′-GCCGUUAGGC-3′ (SEQ ID NO: 20822), or any other Stem II region known in the art, or a nucleotide and/or non-nucleotide linker. Similarly, for other nucleic acid molecules of the instant invention, such as Inozyme, G-cleaver, amberzyme, zinzyme, DNAzyme, antisense, 2-5A antisense, triplex forming nucleic acid, and decoy nucleic acids, other sequences or non-nucleotide linkers can be present that do not interfere with the function of the nucleic acid molecule.


[0075] X can be a linker of ≧2 nucleotides in length, preferably 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 26, 30, where the nucleotides can preferably be internally base-paired to form a stem of preferably ≧2 base pairs. Alternatively or in addition, X may be a non-nucleotide linker. In yet another embodiment, the nucleotide linker (X) can be a nucleic acid aptamer, such as an ATP aptamer, HIV Rev aptamer (RRE), HIV Tat aptamer (TAR) and others (for a review see Gold et al., 1995, Annu. Rev. Biochem., 64, 763; and Szostak & Ellington, 1993, in The RNA World, ed. Gesteland and Atkins, pp. 511, CSH Laboratory Press).


[0076] A “nucleic acid aptamer” as used herein is meant to indicate a nucleic acid sequence capable of interacting with a ligand. The ligand can be any natural or a synthetic molecule, including but not limited to a resin, metabolites, nucleosides, nucleotides, drugs, toxins, transition state analogs, peptides, lipids, proteins, amino acids, nucleic acid molecules, hormones, carbohydrates, receptors, cells, viruses, bacteria and others.


[0077] In yet another embodiment, the non-nucleotide linker (X) is as defined herein. The term “non-nucleotide” as used herein include either abasic nucleotide, polyether, polyamine, polyamide, peptide, carbohydrate, lipid, or polyhydrocarbon compounds. Specific examples include those described by Seela and Kaiser, Nucleic Acids Res. 1990, 18:6353 and Nucleic Acids Res. 1987, 15:3113; Cload and Schepartz, J. Am. Chem. Soc. 1991, 113:6324; Richardson and Schepartz, J. Am. Chem. Soc. 1991, 113:5109; Ma et al., Nucleic Acids Res. 1993, 21:2585 and Biochemistry 1993, 32:1751; Durand et al., Nucleic Acids Res. 1990, 18:6353; McCurdy et al., Nucleosides & Nucleotides 1991, 10:287; Jschke et al., Tetrahedron Lett. 1993, 34:301; Ono et al., Biochemistry 1991, 30:9914; Arnold et al., International Publication No. WO 89/02439; Usman et al., International Publication No. WO 95/06731; Dudycz et al., International Publication No. WO 95/11910 and Ferentz and Verdine, J. Am. Chem. Soc. 1991, 113:4000, all hereby incorporated by reference herein. A “non-nucleotide” further means any group or compound which can be incorporated into a nucleic acid chain in the place of one or more nucleotide units, including either sugar and/or phosphate substitutions, and allows the remaining bases to exhibit their enzymatic activity. The group or compound can be abasic in that it does not contain a commonly recognized nucleotide base, such as adenosine, guanine, cytosine, uracil or thymine. Thus, in one embodiment, the invention features an enzymatic nucleic acid molecule having one or more non-nucleotide moieties, and having enzymatic activity to cleave an RNA or DNA molecule.


[0078] In another aspect of the invention, enzymatic nucleic acid molecules that cleave target RNA molecules and inhibit VEGF-R (specifically flt-1 and flk-1/KDR) activity are expressed from transcription units inserted into DNA or RNA vectors. The recombinant vectors are preferably DNA plasmids or viral vectors. Enzymatic nucleic acid expressing viral vectors can be constructed based on, but not limited to, adeno-associated virus, retrovirus, adenovirus, or alphavirus vectors. Preferably, the recombinant vectors capable of expressing the enzymatic nucleic acid molecules are delivered as described above, and persist in target cells. Alternatively, viral vectors can be used that provide for transient expression of enzymatic nucleic acids. Such vectors can be repeatedly administered as necessary. Once expressed, the enzymatic nucleic acids cleave the target mRNA. Delivery of enzymatic nucleic acids expressing vectors can be systemic, such as by intravenous or intramuscular administration, by administration to target cells ex-planted from the patient followed by reintroduction into the patient, or by any other means that would allow for introduction into the desired target cell.


[0079] By “vectors” is meant any nucleic acid- and/or viral-based technique used to deliver a desired nucleic acid.


[0080] By “patient” is meant an organism which is a donor or recipient of explanted cells or the cells themselves. “Patient” also refers to an organism to which the nucleic acid molecules of the invention can be administered. In one embodiment, the patient is a mammal or mammalian cells. Preferably, the patient is a human or human cells.


[0081] The nucleic acid molecules of the instant invention, individually, or in combination or in conjunction with other drugs, can be used to treat diseases or conditions discussed above. For example, to treat a disease or condition associated with VEGF-R, the patient can be treated, or other appropriate cells can be treated, as is evident to those skilled in the art, individually with a nucleic acid molecule of the invention or in combination with one or more drugs under conditions suitable for the treatment.


[0082] For example, to treat a disease or condition associated with VEGF-R levels, such as cancer (e.g., colorectal cancer, breast cancer) or ocular diseases (e.g., diabetic retinopathy or age related macular degeneration) a patient may be treated, or other appropriate cells may be treated, as is evident to those skilled in the art, individually or in combination with one or more drugs under conditions suitable for the treatment.


[0083] In a further embodiment, the described molecules, such as antisense or enzymatic nucleic acid molecules can be used in combination with other known treatments to treat conditions or diseases discussed above. For example, the described molecules can be used in combination with one or more known therapeutic agents to treat cancer.


[0084] In another embodiment, the invention features nucleic acid-based techniques (e.g., enzymatic nucleic acid molecules (ribozymes such as Inozyme, G-cleaver, amberzyme, zinzyme), DNAzyme, antisense nucleic acids, 2-5A antisense chimeras, triplex forming nucleic acid, decoy nucleic acids, aptamers, allozymes, antisense nucleic acids containing RNA cleaving chemical groups (Cook et al., U.S. Pat. No. 5,359,051)] and methods for their use to down regulate or inhibit the expression of genes capable of inducing angiogenesis (e.g., flt-1 and kdr).


[0085] In another embodiment, the invention features nucleic acid-based techniques (e.g., enzymatic nucleic acid molecules (ribozymes such as Inozyme, G-cleaver, amberzyme, zinzyme), DNAzyme, antisense nucleic acids, 2-5A antisense chimeras, triplex forming nucleic acid, decoy nucleic acids, aptamers, allozymes, antisense nucleic acids containing RNA cleaving chemical groups (Cook et al., U.S. Pat. No. 5,359,051)] and methods for their use to down regulate or inhibit the expression of VEGF receptor.


[0086] Other features and advantages of the invention will be apparent from the following description of the preferred embodiments thereof, and from the claims.







BRIEF DESCRIPTION OF THE DRAWINGS

[0087]
FIG. 1 is a diagrammatic representation of the hammerhead ribozyme domain known in the art. Stem II can be ≧2 base-pair long.


[0088]
FIGS. 2

a
-d show hammerhead ribozyme substrate motifs. FIG. 2a is a diagrammatic representation of the hammerhead ribozyme domain known in the art; FIG. 2b is a diagrammatic representation of the hammerhead ribozyme as divided by Uhlenbeck (1987, Nature, 327, 596-600) into a substrate and enzyme portion; FIG. 2c is a similar diagram showing the hammerhead divided by Haseloff and Gerlach (1988, Nature, 334, 585-591) into two portions; and FIG. 2d is a similar diagram showing the hammerhead divided by Jeffries and Symons (1989, Nucl. Acids. Res., 17, 1371-1371) into two portions.


[0089]
FIG. 3 is a diagrammatic representation of the general structure of a hairpin ribozyme. Helix 2 (H2) is provided with at least 4 base pairs (i.e., n is 1, 2, 3 or 4) and helix 5 can be optionally provided of length 2 or more bases (preferably 3-20 bases, i.e., m is from 1-20 or more). Helix 2 and helix 5 can be covalently linked by one or more bases (i.e., r is ≧1 base). Helix 1, 4 or 5 can also be extended by 2 or more base pairs (e.g., 4-20 base pairs) to stabilize the ribozyme structure, and preferably is a protein binding site. In each instance, each N and N′ independently is any normal or modified base and each dash represents a potential base-pairing interaction. These nucleotides can be modified at the sugar, base or phosphate. Complete base-pairing is not required in the helices, but is preferred. Helix 1 and 4 can be of any size (i.e., o and p is each independently from 0 to any number, e.g., 20) as long as some base-pairing is maintained. Essential bases are shown as specific bases in the structure, but those in the art will recognize that one or more can be modified chemically (abasic, base, sugar and/or phosphate modifications) or replaced with another base without significant effect. Helix 4 can be formed from two separate molecules, i.e., without a connecting loop. The connecting loop when present can be a ribonucleotide with or without modifications to its base, sugar or phosphate. “q” is ≧2 bases. The connecting loop can also be replaced with a non-nucleotide linker molecule. H refers to bases A, U, or C. Y refers to pyrimidine bases. “______” refers to a covalent bond.


[0090]
FIG. 4 is a representation of the general structure of the hepatitis delta virus ribozyme domain known in the art.


[0091]
FIG. 5 is a representation of the general structure of the VS RNA ribozyme domain.


[0092]
FIG. 6 is a schematic representation of an RNAseH accessibility assay. Specifically, the left side of FIG. 6 is a diagram of complementary DNA oligonucleotides bound to accessible sites on the target RNA. Complementary DNA oligonucleotides are represented by broad lines labeled A, B, and C. Target RNA is represented by the thin, twisted line. The right side of FIG. 6 is a schematic of a gel separation of uncut target RNA from a cleaved target RNA. Detection of target RNA is by autoradiography of body-labeled, T7 transcript. The bands common to each lane represent uncleaved target RNA; the bands unique to each lane represent the cleaved products.


[0093]
FIG. 7 shows the effect of hammerhead ribozymes targeted against flt-1 receptor on the binding of VEGF to the surface of human microvascular endothelial cells. Sequences of the ribozymes used are shown in Table II; the length of stem II region is 3 bp. The hammerhead ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions (see FIG. 11); U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose. The results of two separate experiments are shown as separate bars for each set. Each bar represents the average of triplicate samples. The standard deviation is shown with error bars. For the fit-1 data, 500 nM ribozyme (3:1 charge ratio with LipofectAMINE®) was used. Control 1-10 is the control for ribozymes 307-2797, control 11-20 is the control for ribozymes 3008-5585. The Control 1-10 and Control 11-20 represent the treatment of cells with LipofectAMINE® alone without any ribozymes.


[0094]
FIG. 8 shows the effect of hammerhead ribozymes targeted against KDR receptor on the binding of VEGF to KDR on the surface of human microvascular endothelial cells. Sequences of the ribozymes used are shown in Table IV; the length of stem II region is 3 bp. The hammerhead ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions (see FIG. 11); U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose. The Control 1-10 and Control 11-20 represent the treatment of cells with LipofectAMINE® alone without any ribozymes. Irrel. RZ, is a control experiment wherein the cells are treated with a non-KDR-targeted ribozyme complexed with Lipofectamine®. 200 nM ribozyme (3:1 charge ratio with LipofectAMINE®) was used. In addition to the KDR-targeted ribozymes, the effect on VEGF binding of a ribozyme targeted to an irrelevant mRNA (irrel. RZ) is also shown. Because the affinity of KDR for VEGF is about 10-fold lower than the affinity of flt-1 for VEGF, a higher concentration of VEGF was used in the binding assay.


[0095]
FIG. 9 shows the specificity of hammerhead ribozymes targeted against flt-1 receptor. Inhibition of the binding of VEGF, urokinase plasminogen activator (UPA) and fibroblast growth factor (FGF) to their corresponding receptors as a function of anti-FLT ribozymes is shown. The sequence and description of the ribozymes used are as described in FIG. 7 above. The average of triplicate samples is given; percent inhibition as calculated below.


[0096]
FIG. 10 shows the inhibition of the proliferation of Human aortic endothelial cells (HAEC) mediated by phosphorothioate antisense oligodeoxynucleotides targeted against human KDR receptor RNA. Cell proliferation (O.D. 490) as a function of antisense oligodeoxynucleotide concentration is shown. KDR 21AS represents a 21 nt phosphorothioate antisense oligodeoxynucleotide targeted against KDR RNA. KDR 21 Scram represents a 21 nt phosphorothioate oligodeoxynucleotide having a scrambled sequence. LF represents the lipid carrier Lipofectin.


[0097]
FIGS. 11A and B show a diagrammatic representation of hammerhead ribozymes targeted against flt-1 RNA and in vitro cleavage of flt-1 RNA by hammerhead ribozymes. The hammerhead (HH) ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (designated as 3′-1H). FIG. 11A shows hammerhead ribozymes 1358 HH-A and 4229 HH-A, which contain a 3 base-paired stem II region. FIG. 11B shows hammerhead ribozymes 1358 HH-B and 4229 HH-B, which contain a 4 base-paired stem II region.


[0098]
FIG. 12 shows a diagrammatic representation of hammerhead (HH) ribozymes targeted against sites 1358 and 4229 within the flt-1 RNA. The hammerhead (HH) ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 position contains 2′-C-allyl modification, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (designated as 3′-iH).


[0099]
FIG. 13 shows inhibition of human microvascular endothelial cell proliferation mediated by anti-KDR hammerhead ribozymes. The figure is a graphical representation of the inhibition of cell proliferation mediated by hammerhead ribozymes targeted against sites 527, 730, 3702 and 3950 within the KDR RNA. Irrelevant HH RZ is a hammerhead ribozyme targeted to an irrelevant target. All of these ribozymes, including the Irrelevant HH RZ, were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ termini contain phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (3′-iH).


[0100]
FIG. 14 shows in vitro cleavage of KDR RNA by hammerhead ribozymes. The hammerhead (HH) ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (designated as 3′-iH). 726 HH and 527 HH contain 4 base-paired stem II region. Percent in vitro cleavage kinetics as a function of time of HH ribozymes targeted against sites 527 and 726 within the KDR RNA is shown.


[0101]
FIG. 15 shows in vitro cleavage of KDR RNA by hammerhead ribozymes. The hammerhead (HH) ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (designated as 3′-iH). 3702 HH and 3950 HH contain 4 base-paired stem II region. Percent in vitro cleavage kinetics as a function of time of HH ribozymes targeted against sites 3702 and 3950 within the KDR RNA is shown.


[0102]
FIG. 16 shows in vitro cleavage of RNA by hammerhead ribozymes that are targeted to sites that are conserved between flt-1 and KDR RNA. The hammerhead (HH) ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (designated as 3′-iH). FLT/KDR-IHH ribozyme was synthesized with either a 4 base-paired or a 3 base-paired stem II region. FLT/KDR-IHH can cleave site 3388 within fit-1 RNA and site 3151 within KDR RNA. Percent in vitro cleavage kinetics as a function of time of HH ribozymes targeted against sites 3702 and 3950 within the KDR RNA is shown.


[0103]
FIG. 17 shows inhibition of human microvascular endothelial cell proliferation mediated by anti-KDR and anti-flt-1 hammerhead ribozymes. The figure is a graphical representation of the inhibition of cell proliferation mediated by hammerhead ribozymes targeted against sites KDR sites-527, 726 or 3950 or flt-1 site 4229. The figure also shows enhanced inhibition of cell proliferation by a combination of fit-1 and KDR hammerhead ribozymes. 4229+527, indicates the treatment of cells with both the fit 4229 and the KDR 527 ribozymes. 4229+726, indicates the treatment of cells with both the fit 4229 and the KDR 726 ribozymes. 4229+3950, indicates the treatment of cells with both the fit 4229 and the KDR 3950 ribozymes. VEGF−, indicates the basal level of cell proliferation in the absence of VEGF. A, indicates catalytically active ribozyme; I, indicates catalytically inactive ribozyme. All of these ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ termini contain phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (3′-iH).


[0104]
FIG. 18 shows the inhibition of VEGF-induced angiogenesis in rat cornea mediated by anti-flt-1 hammerhead ribozyme. All of these ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 position contains 2′-C-allyl modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ termini contain phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose (3′-iH). A decrease in the Surface Area corresponds to a reduction in angiogenesis. VEGF alone corresponds to treatment of the cornea with VEGF and no ribozymes. Vehicle alone corresponds to the treatment of the cornea with the carrier alone and no VEGF. This control gives a basal level of Surface Area. Active 4229 HH, corresponds to the treatment of cornea with the flt-1 4229 HH ribozyme in the absence of any VEGF. This control also gives a basal level of Surface Area. Active 4229 HH+VEGF, corresponds to the co-treatment of cornea with the flt-1 4229 HH ribozyme and VEGF. Inactive 4229 HH+VEGF, corresponds to the co-treatment of cornea with a catalytically inactive version of 4229 HH ribozyme and VEGF.


[0105]
FIG. 19 shows ribozyme-mediated inhibition of cell proliferation. Cultured HMVEC-d were treated with ribozyme or attenuated controls as LIPOFECTAMINE™ complexes. After treatment, cells were stimulated with VEGF165 or bFGF and allowed to grow for 48 h prior to determining the cell number. Each ribozyme was tested in triplicate at three concentrations and data are presented as mean cell number per well+SD. The data obtained following ribozyme treatment and VEGF stimulation are presented in panels A & B for anti-Flt-1 ribozymes and panels D & E for anti-KDR ribozymes. Representative data obtained following ribozyme treatment and bFGF stimulation are shown in panel C for one anti-Flt-1 ribozyme and in panel F for one anti-KDR ribozyme. In all panels, active ribozymes are represented with filled symbols; attenuated controls with open symbols. In addition to the ribozymes and attenuated controls listed in Table XII, a second set having the same sequences but with an additional basepair in the “stem II” region of the ribozyme are also shown for VEGF-induced proliferation studies. These 4 bp stem II ribozymes and attenuated controls have one additional base pair such that the stem II/loop sequence is ggccgaaaggcc. Therefore, ribozymes and controls with 3 or 4 basepair stem IIs are denoted with circles and squares, respectively. The data for one irrelevant ribozyme (filled triangle, panel B) are also shown. This irrelevant ribozyme contains an active core sequence but has no binding site in either Flt-1 or KDR mRNA. Its sequence is 5′-gsasasgsgaacUGAuGaggccgaaaggccGaaAgauggcT-3′ with modifications as in Table XII except that T indicates a 3′-3′ inverted deoxythymidine. For reference, the average number of cells in control wells after 48 h in the absence of VEGF or bFGF for each of the panels are as follows: A, B, C, 12477±617; D, E, F, 17182±1053.


[0106]
FIG. 20 shows target specificity of anti-Flt-1 and KDR ribozymes. Cultured HMVEC-d were treated with LIPOFECTAMINE™ complexes containing 200 nM active ribozyme (A) or attenuated control (C) and analyzed by RNAse protection following 24 h of VEGF-stimulated growth. Data obtained for ribozymes and attenuated controls that target Flt-1 site 4229 or KDR site 726 are shown. Data were normalized to the level of an internal mRNA control (cyclophilin) and are presented as percent decrease in Flt-1 (left panel) or KDR mRNA (right panel) relative to an untreated control. Error bars indicate the range of duplicate samples.


[0107]
FIG. 21 shows antiangiogenic efficacy of ribozyme in the rat corneal model of VEGF-induced angiogenesis. The percent inhibition of VEGF-induced angiogenesis for locally administered anti-Flt-1 (site 4229) ribozyme (filled circles) and their attenuated controls (open circles) are plotted over the dose range tested. Pixels associated with background structures including the iris were subtracted from all treatment groups. Data are expressed as mean percent reduction in VEGF-induced angiogenesis±SEM. *p<0.05 relative to VEGF/vehicle treated controls by Dunnett's, **p<0.05 relative to attenuated dose-matched controls by Tukey-Kramer.


[0108]
FIG. 22 shows antiangiogenic efficacy of ribozyme in the rat corneal model of VEGF-induced angiogenesis. The percent inhibition of VEGF-induced angiogenesis for locally administered anti-KDR (site 726) ribozyme (filled circles) and their attenuated controls (open circles) are plotted over the dose range tested. Pixels associated with background structures including the iris were subtracted from all treatment groups. Data are expressed as mean percent reduction in VEGF-induced angiogenesis±SEM. *p<0.05 relative to VEGF/vehicle treated controls by Dunnett's, **p<0.05 relative to attenuated dose-matched controls by Tukey-Kramer.


[0109]
FIG. 23 shows the effect of subcutaneous bolus administration of ANGIOZYME™ in a mouse Lewis Lung Carcinoma (LLC) model.


[0110]
FIG. 24 shows the effect of ANGIOZYME™ in combination with gemcitabine or cyclophosphamide on primary tumor growth in the mouse LLC model.


[0111]
FIG. 25 shows the effect of ANGIOZYME™ in combination with gemcitabine or cyclophosphamide on tumor metastases in the mouse LLC model.


[0112]
FIG. 26 shows a secondary structure model of ANGIOZYME™ ribozyme bound to its RNA target.


[0113]
FIG. 27 shows a time course of inhibition of primary tumor growth following systemic administration of ANGIOZYME™ in the LLC mouse model.


[0114]
FIG. 28 shows inhibition of primary tumor growth following systemic administration of ANGIOZYME™ according to a certain dosing regimen in the LLC mouse model.


[0115]
FIG. 29 shows a dose-dependent inhibition of tumor metastases following systemic administration of ANGIOZYME™ in a mouse colorectal model.


[0116]
FIG. 30 shows inhibition of liver metastases following systemic administration of ANGIOZYME™ in a mouse colorectal model.


[0117]
FIG. 31 is a graph showing the plasma concentration profile of ANGIOZYME™ after a single subcutaneous (SC) dose of 10, 30, 100 or 300 mg/m2.


[0118]
FIG. 32 shows an example of the Zinzyme enzymatic nucleic acid motif that is chemically stabilized (see for example Beigelman et al., International PCT publication No. WO 99/55857, incorporated by reference herein; also referred to as Class A or Class II Motif). The Zinzyme motif is a class of enzymatic nucleic molecules that do not require the presence of a ribonucleotide (2′-OH) group for its activity.


[0119]
FIG. 33 shows an example of a DNAzyme motif described generally, for example in Santoro et al., 1997, PNAS, 94, 4262.


[0120]
FIGS. 34A and B show a mouse model protocol and results of proliferative retinopathy. FIG. 34A shows anoutline for the mouse model of proliferative retinopathy showing the points of ribozyme administration. FIG. 34B shows a graph demonstrating the efficacy of a VEGF-receptor-targeted enzymatic nucleic acid molecule in a mouse model of proliferative retinopathy.







DETAILED DESCRIPTION OF THE INVENTION

[0121] Mechanism of Action of Nucleic Acid Molecules of the Invention


[0122] Antisense: Antisense molecules can be modified or unmodified RNA, DNA, or mixed polymer oligonucleotides and primarily function by specifically binding to matching sequences resulting in inhibition of peptide synthesis (Wu-Pong, November 1994, BioPharm, 20-33). The antisense oligonucleotide binds to target RNA by Watson Crick base-pairing and blocks gene expression by preventing ribosomal translation of the bound sequences either by steric blocking or by activating RNase H enzyme. Antisense molecules can also alter protein synthesis by interfering with RNA processing or transport from the nucleus into the cytoplasm (Mukhopadhyay & Roth, 1996, Crit. Rev. in Oncogenesis 7, 151-190).


[0123] In addition, binding of single stranded DNA to RNA can result in nuclease degradation of the heteroduplex (Wu-Pong, supra; Crooke, supra). To date, the only backbone modified DNA chemistry which acts as substrates for RNase H are phosphorothioates and phosphorodithioates. Recently it has been reported that 2′-arabino and 2′-fluoro arabino-containing oligos can also activate RNase H activity.


[0124] A number of antisense molecules have been described that utilize novel configurations of chemically modified nucleotides, secondary structure, and/or RNase H substrate domains (Woolf et al., International PCT Publication No. WO 98/13526; Thompson et al., U.S. Ser. No. 60/082,404 which was filed on Apr. 20, 1998; Hartmann et al., U.S. Ser. No. 60/101,174 which was filed on Sep. 21, 1998) all of these are incorporated by reference herein in their entirety.


[0125] Triplex Forming Oligonucleotides (TFO): Single stranded DNA can be designed to bind to genomic DNA in a sequence specific manner. TFOs are comprised of pyrimidine-rich oligonucleotides which bind DNA helices through Hoogsteen Base-pairing (Wu-Pong, supra). The resulting triple helix composed of the DNA sense, DNA antisense, and TFO disrupts RNA synthesis by RNA polymerase. The TFO mechanism can result in gene expression or cell death since binding may be irreversible (Mukhopadhyay & Roth, supra).


[0126] 2-5A Antisense Chimera: The 2-5A system is an interferon mediated mechanism for RNA degradation found in higher vertebrates (Mitra et al., 1996, Proc Nat Acad Sci USA 93, 6780-6785). Two types of enzymes, 2-5A synthetase and RNase L, are required for RNA cleavage. The 2-5A synthetases require double stranded RNA to form 2′-5′ oligoadenylates (2-5A). 2-5A then acts as an allosteric effector for utilizing RNase L which has the ability to cleave single stranded RNA. The ability to form 2-5A structures with double stranded RNA makes this system particularly useful for inhibition of viral replication.


[0127] (2′-5′) oligoadenylate structures can be covalently linked to antisense molecules to form chimeric oligonucleotides capable of RNA cleavage (Torrence, supra). These molecules putatively bind and activate a 2-5A dependent RNase, the oligonucleotide/enzyme complex then binds to a target RNA molecule which can then be cleaved by the RNase enzyme.


[0128] Enzymatic Nucleic Acid: Seven basic varieties of naturally-occurring enzymatic RNAs are presently known. In addition, several in vitro selection (evolution) strategies (Orgel, 1979, Proc. R. Soc. London, B 205, 435) have been used to evolve new nucleic acid catalysts capable of catalyzing cleavage and ligation of phosphodiester linkages (Joyce, 1989, Gene, 82, 83-87; Beaudry et al., 1992, Science 257, 635-641; Joyce, 1992, Scientific American 267, 90-97; Breaker et al., 1994, TIBTECH 12, 268; Bartel et al., 1993, Science 261:1411-1418; Szostak, 1993, TIBS 17, 89-93; Kumar et al., 1995, FASEB J., 9, 1183; Breaker, 1996, Curr. Op. Biotech., 7, 442; Santoro et al., 1997, Proc. Natl. Acad. Sci., 94, 4262; Tang et al., 1997, RNA 3, 914; Nakamaye & Eckstein, 1994, supra; Long & Uhlenbeck, 1994, supra; Ishizaka et al., 1995, supra; Vaish et al., 1997, Biochemistry 36, 6495; all of these are incorporated by reference herein). Each can catalyze a series of reactions including the hydrolysis of phosphodiester bonds in trans (and thus can cleave other RNA molecules) under physiological conditions.


[0129] Enzymatic nucleic acid molecules of this invention block to some extent VEGF-R (specifically flt-1 and flk-1/KDR) production and can be used to treat disease or diagnose such disease. Enzymatic nucleic acid molecules are delivered to cells in culture, to cells or tissues in animal models of angiogenesis and/or RA and to human cells or tissues ex vivo or in vivo. Enzymatic nucleic acid molecule cleavage of VEGF-R RNAs (specifically RNAs that encode flt-1 and flk-1/KDR) in these systems can alleviate disease symptoms.


[0130] The enzymatic nature of enzymatic nucleic acid molecules, such as ribozymes, has significant advantages, such as the concentration of enzymatic nucleic acid necessary to affect a therapeutic treatment is lower. This advantage reflects the ability of the enucleic acid molecule to act enzymatically. Thus, a single enzymatic nucleic acid molecule is able to cleave many molecules of target RNA. In addition, the enzymatic nucleic acid molecule is a highly specific inhibitor, with the specificity of inhibition depending not only on the base-pairing mechanism of binding to the target RNA, but also on the mechanism of target RNA cleavage. Single mismatches, or base-substitutions, near the site of cleavage can be chosen to completely eliminate catalytic activity of an enzymatic nucleic acid molecule.


[0131] Nucleic acid molecules having an endonuclease enzymatic activity are able to repeatedly cleave other separate RNA molecules in a nucleotide base sequence-specific manner. Such enzymatic nucleic acid molecules can be targeted to virtually any RNA transcript, and achieved efficient cleavage in vitro (Zaug et al., 324, Nature 429 1986; Uhlenbeck, 1987 Nature 328, 596; Kim et al., 84 Proc. Natl. Acad. Sci. USA 8788, 1987; Dreyfus, 1988, Einstein Quart. J. Bio. Med., 6, 92; Haseloff and Gerlach, 334 Nature 585, 1988; Cech, 260 JAMA 3030, 1988; and Jefferies et al., 17 Nucleic Acids Research 1371, 1989; Santoro et al., 1997 supra).


[0132] Because of their sequence specificity, enzymatic nucleic acids, such as trans-cleaving ribozymes can be used as therapeutic agents for human disease (Usman & McSwiggen, 1995 Ann. Rep. Med. Chem. 30, 285-294; Christoffersen and Marr, 1995 J. Med. Chem. 38, 2023-2037). Enzymatic nucleic acid molecules can be designed to cleave specific RNA targets within the background of cellular RNA. Such a cleavage event renders the RNA non-functional and abrogates protein expression from that RNA. In this manner, synthesis of a protein associated with a disease state can be selectively inhibited.


[0133] Target sites


[0134] Targets for useful enzymatic nucleic acid molecules and antisense nucleic acids can be determined as disclosed in Draper et al., WO 93/23569; Sullivan et al., WO 93/23057; Thompson et al., WO 94/02595; Draper et al., WO 95/04818; McSwiggen et al., U.S. Pat. No. 5,525,468, and hereby incorporated by reference herein in totality. Other examples include the following PCT applications which concern inactivation of expression of disease-related genes: WO 95/23225, WO 95/13380, WO 94/02595, incorporated by reference herein. Rather than repeat the guidance provided in those documents here, below are provided specific examples of such methods, not limiting to those with skill in the art. Enzymatic nucleic acid molecules to such targets are designed as described in those applications and synthesized to be tested in vitro and in vivo, as also described. The sequence of human and mouse flt-1, KDR and/or flk-1 mRNAs were screened for optimal enzymatic nucleic acid target sites using a computer folding algorithn. Hammerhead, hairpin, NCH, or G-Cleaver ribozyme cleavage sites were identified. These sites are shown in Tables II to IX, XIV-XIX, XXII, and XXIII (all sequences are 5′ to 3′ in the tables; X can be any base-paired sequence, the actual sequence is not relevant here). The nucleotide base position is noted in the Tables as that site to be cleaved by the designated type of ribozyme. While mouse and human sequences can be screened and enzymatic nucleic acid molecules thereafter designed, the human targeted sequences are of most utility. However, as discussed in Stinchcomb et al., WO 95/23225, mouse targeted enzymatic nucleic acid can be useful to test efficacy of action of the enzymatic nucleic acid molecule prior to testing in humans. The nucleotide base position is noted in the Tables as that site to be cleaved by the designated type of enzymatic nucleic acid.


[0135] For example, hammerhead or hairpin ribozymes were designed that could bind and cleave target RNA in a sequence-specific manner. The ribozymes were individually analyzed by computer folding (Jaeger et al., 1989 Proc. Natl. Acad. Sci. USA, 86, 7706) to assess whether the ribozyme sequences fold into the appropriate secondary structure. Those ribozymes with unfavorable intramolecular interactions between the binding arms and the catalytic core were eliminated from consideration. Varying binding arm lengths can be chosen to optimize activity.


[0136] Referring to FIG. 6, mRNA was screened for accessible cleavage sites by the method described generally in Draper et al., PCT WO93/23569, hereby incorporated by reference herein. Briefly, DNA oligonucleotides complementary to potential hammerhead or hairpin ribozyme cleavage sites were synthesized. A polymerase chain reaction was used to generate substrates for T7 RNA polymerase transcription from human and mouse flt-1, KDR and/or flk-1 cDNA clones. Labeled RNA transcripts were synthesized in vitro from the templates. The oligonucleotides and the labeled transcripts were annealed, RNAseH was added and the mixtures were incubated for the designated times at 37° C. Reactions were stopped and RNA separated on sequencing polyacrylamide gels. The percentage of the substrate cleaved was determined by autoradiographic quantitation using a PhosphorImaging system. From these data, antisense oligonucleotides, and ribozymes, such as hammerhead or hairpin ribozyme sites are chosen as the most accessible.


[0137] Ribozymes of the hammerhead or hairpin motif were designed to anneal to various sites in the mRNA message. The binding arms are complementary to the target site sequences described above. The ribozymes were chemically synthesized. The method of synthesis used follows the procedure for normal RNA synthesis as described below and in Usman et al., 1987 J. Am. Chem. Soc., 109, 7845; Scaringe et al., 1990 Nucleic Acids Res., 18, 5433; and Wincott et al., 1995 Nucleic Acids Res. 23, 2677-2684.


[0138] Synthesis of Nucleic acid Molecules


[0139] Synthesis of nucleic acids greater than 100 nucleotides in length is difficult using automated methods, and the therapeutic cost of such molecules is prohibitive. In this invention, small nucleic acid motifs (“small refers to nucleic acid motifs no more than 100 nucleotides in length, preferably no more than 80 nucleotides in length, and most preferably no more than 50 nucleotides in length; e.g., antisense oligonucleotides, hammerhead or the hairpin ribozymes) are preferably used for exogenous delivery. The simple structure of these molecules increases the ability of the nucleic acid to invade targeted regions of RNA structure. Exemplary molecules of the instant invention were chemically synthesized, and others can similarly be synthesized. Oligodeoxyribonucleotides were synthesized using standard protocols as described in Caruthers et al., 1992, Methods in Enzymology 211,3-19, and is incorporated herein by reference.


[0140] The method of synthesis used for normal RNA including certain enzymatic nucleic acid molecules follows the procedure as described in Usman et al., 1987 J. Am. Chem. Soc., 109, 7845; Scaringe et al., 1990 Nucleic Acids Res., 18, 5433; and Wincott et al., 1995 Nucleic Acids Res. 23, 2677-2684 and makes use of common nucleic acid protecting and coupling groups, such as dimethoxytrityl at the 5′-end, and phosphoramidites at the 3′-end. In a non-limiting example, small scale syntheses were conducted on a 394 Applied Biosystems, Inc. synthesizer using a 0.2 μmol scale protocol with a 7.75 min coupling step for alkylsilyl protected nucleotides and a 2.5 min coupling step for 2′-O-methylated nucleotides. Table XI outlines the amounts and the contact times of the reagents used in the synthesis cycle. Alternatively, syntheses at the 0.2 μmol scale can be done on a 96-well plate synthesizer, such as the instrument produced by Protogene (Palo Alto, Calif.) with minimal modification to the cycle. A 15-fold excess (31 μL of 0.1 M=3.1 μmol) of phosphoramidite and a 38.7-fold excess of S-ethyl tetrazole (31 μL of 0.25 M=7.75 μmol) relative to polymer-bound 5′-hydroxyl was used in each coupling cycle. Average coupling yields on the 394 Applied Biosystems, Inc. synthesizer, determined by colorimetric quantitation of the trityl fractions, were 97.5-99%. Other oligonucleotide synthesis reagents for the 394 Applied Biosystems, Inc. synthesizer; detritylation solution was 3% TCA in methylene chloride (ABI); capping was performed with 16% N-methylimidazole in THF (ABI) and 10% acetic anhydride/10% 2,6-lutidine in THF (ABI); oxidation solution was 16.9 mM I2, 49 mM pyridine, 9% water in THF (PERSEPTIVE™). Burdick & Jackson Synthesis Grade acetonitrile was used directly from the reagent bottle. S-Ethyltetrazole solution (0.25 M in acetonitrile) was made up from the solid obtained from American International Chemical, Inc.


[0141] Deprotection of the RNA was performed using either a two-pot or one-pot protocol. For the two-pot protocol, the polymer-bound trityl-on oligoribonucleotide was transferred to a 4 mL glass screw top vial and suspended in a solution of 40% aq. methylamine (1 mL) at 65° C. for 10 min. After cooling to −20° C., the supernatant was removed from the polymer support. The support was washed three times with 1.0 mL of EtOH:MeCN:H2O/3:1:1, vortexed and the supernatant was then added to the first supernatant. The combined supernatants, containing the oligoribonucleotide, were dried to a white powder. The base deprotected oligoribonucleotide was resuspended in anhydrous TEA/HF/NMP solution (300 μL of a solution of 1.5 mL N-methylpyrrolidinone, 750 μL TEA and 1 mL TEA.3HF to provide a 1.4 M HF concentration) and heated to 65° C. After 1.5 h, the oligomer was quenched with 1.5 M NH4HCO3.


[0142] Alternatively, for the one-pot protocol, the polymer-bound trityl-on oligoribonucleotide was transferred to a 4 mL glass screw top vial and suspended in a solution of 33% ethanolic methylamine/DMSO:1/1 (0.8 mL) at 65° C. for 15 min. The vial was brought to r.t. TEA.3HF (0.1 mL) was added and the vial was heated at 65° C. for 15 min. The sample was cooled at −20° C. and then quenched with 1.5 M NH4HCO3.


[0143] For purification of the trityl-on oligomers, the quenched NH4HCO3 solution was loaded onto a C-18 containing cartridge that had been prewashed with acetonitrile followed by 50 mM TEAA. After washing the loaded cartridge with water, the RNA was detritylated with 0.5% TFA for 13 min. The cartridge was then washed again with water, salt exchanged with 1 M NaCl and washed with water again. The oligonucleotide was then eluted with 30% acetonitrile.


[0144] Inactive hammerhead ribozymes or binding attenuated control (BAC) oligonucleotides) were synthesized by substituting a U for G5 and a U for A14 (numbering from Hertel, K. J., et al., 1992, Nucleic Acids Res., 20, 3252).


[0145] The average stepwise coupling yields were >98% (Wincott et al., 1995 Nucleic Acids Res. 23, 2677-2684). Those of ordinary skill in the art will recognize that the scale of synthesis can be adapted to be larger or smaller than the example described above including but not limited to 96 well format, all that is important is the ratio of chemicals used in the reaction.


[0146] Alternatively, the nucleic acid molecules of the present invention can be synthesized separately and joined together by ligation (Moore et al., 1992, Science 256, 9923; Draper et al., International PCT publication No. WO 93/23569; Shabarova et al., 1991, Nucleic Acids Research 19, 4247).


[0147] Enzymatic nucleic acid molecules are modified extensively to enhance stability by modification with nuclease resistant groups, for example, 2′-amino, 2′-C-allyl, 2′-flouro, 2′-O-methyl, 2′-H (for a review see Usman and Cedergren, 1992 TIBS 17, 34; Usman et al., 1994 Nucleic Acids Symp. Ser. 31, 163). Enzymatic nucleic acid molecules are purified by gel electrophoresis using general methods or are purified by high pressure liquid chromatography (HPLC; See Wincott et al., Supra, the totality of which is hereby incorporated herein by reference) and are resuspended in water.


[0148] For example, the sequences of the ribozymes that are chemically synthesized, useful in this study, are shown in Tables II to IX, XIV-XIX, XXII, and XXIII. Those in the art will recognize that these sequences are representative only of many more such sequences where the enzymatic portion of the ribozyme (all but the binding arms) is altered to affect activity. Stem-loop IV sequence of hairpin ribozymes listed in, for example, Table III (5′-CACGUUGUG-3′) can be altered (substitution, deletion, and/or insertion) to contain any sequence, provided a minimum of two base-paired stem structure can form. Preferably, no more than 200 bases are inserted at these locations. The sequences listed in Tables II to X, XII-XIX, XXII, and XXIII may be formed of ribonucleotides or other nucleotides or non-nucleotides. Such ribozymes with enzymatic activity are equivalent to the ribozymes described specifically in the Tables.


[0149] Optimizing Activity of the Nucleic Acid Molecule of the Invention


[0150] Enzymatic nucleic acid activity can be optimized as described by Stinchcomb et al., supra. The details will not be repeated here, but include altering the length of the enzymatic nucleic acid binding arms (stems I and III, see FIG. 2c), or chemically synthesizing enzymatic nucleic acid with modifications that prevent their degradation by serum ribonucleases (see e.g., Eckstein et al., International Publication No. WO 92/07065; Perrault et al., 1990 Nature 344, 565; Pieken et al., 1991 Science 253, 314; Usman and Cedergren, 1992 Trends in Biochem. Sci. 17, 334; Usman et al., International Publication No. WO 93/15187; Rossi et al., International Publication No. WO 91/03162; Beigelman et al., 1995 J. Biol. Chem. in press; as well as Sproat, U.S. Pat. No. 5,334,711 which describe various chemical modifications that can be made to the sugar moieties of enzymatic RNA molecules). Modifications which enhance their efficacy in cells, and removal of stem II bases to shorten RNA synthesis times and reduce chemical requirements are desired. (All these publications are hereby incorporated by reference herein).


[0151] There are several examples in the art describing sugar, base and phosphate modifications that can be introduced into enzymatic nucleic acid molecules without significantly effecting catalysis and with significant enhancement in their nuclease stability and efficacy. For example, enzymatic nucleic acid molecules are modified to enhance stability and/or enhance catalytic activity by modification with nuclease resistant groups, for example, 2′-amino, 2′-C-allyl, 2′-fluoro, 2′-O-methyl, 2′-H, nucleotide base modifications (for a review see Usman and Cedergren, 1992 TIBS 17, 34; Usman et al., 1994 Nucleic Acids Symp. Ser. 31, 163; Burgin et al., 1996 Biochemistry 35, 14090). Sugar modification of enzymatic nucleic acid molecules have been extensively described in the art (see Eckstein et al., International Publication PCT No. WO 92/07065; Perrault et al. Nature 1990, 344, 565-568; Pieken et al. Science 1991, 253, 314-317; Usman and Cedergren, Trends in Biochem. Sci. 1992, 17, 334-339; Usman et al. International Publication PCT No. WO 93/15187; Sproat, U.S. Pat. No. 5,334,711 and Beigelman et al., 1995 J. Biol. Chem. 270, 25702; all of the references are hereby incorporated in their totality by reference herein). Such publications describe general methods and strategies to determine the location of incorporation of sugar, base and/or phosphate modifications and the like into enzymatic nucleic acid without inhibiting catalysis, and are incorporated by reference herein. In view of such teachings, similar modifications can be used as described herein to modify the nucleic acid catalysts of the instant invention.


[0152] Nucleic acid catalysts having chemical modifications which maintain or enhance enzymatic activity are provided. Such nucleic acid is also generally more resistant to nucleases than unmodified nucleic acid. Thus, in a cell and/or in vivo the activity may not be significantly lowered. As exemplified herein such enzymatic nucleic acid molecules are useful in a cell and/or in vivo even if activity over all is reduced 10 fold (Burgin et al., 1996, Biochemistry, 35, 14090). Such enzymatic nucleic acid molecules herein are said to “maintain” the enzymatic activity of an all RNA enzymatic nucleic acid molecules.


[0153] Therapeutic nucleic acid molecules (e.g., enzymatic nucleic acid molecules and antisense nucleic acid molecules) delivered exogenously must optimally be stable within cells until translation of the target RNA has been inhibited long enough to reduce the levels of the undesirable protein. This period of time varies between hours to days depending upon the disease state. Clearly, these nucleic acid molecules must be resistant to nucleases in order to function as effective intracellular therapeutic agents. Improvements in the chemical synthesis of nucleic acid molecules described in the instant invention and in the art have expanded the ability to modify nucleic acid molecules by introducing nucleotide modifications to enhance their nuclease stability as described above.


[0154] By “enhanced enzymatic activity” is meant to include activity measured in cells and/or in vivo where the activity is a reflection of both catalytic activity and enzymatic nucleic acid stability. In this invention, the product of these properties is increased or not significantly (less that 10 fold) decreased in vivo compared to an all RNA enzymatic nucleic acid molecule.


[0155] In one embodiment, the nucleic acid molecules comprises a 5′ and/or a 3′-cap structure.


[0156] By “cap structure” is meant chemical modifications, which have been incorporated at the terminus of the oligonucleotide (see for example Wincott et al., WO 97/26270, incorporated by reference herein). These terminal modifications protect the nucleic acid molecule from exonuclease degradation, and may help in delivery and/or localization within a cell. The cap may be present at the 5′-terminus (5′-cap) or at the 3′-terminus (3′-cap) or may be present on both terminus. In non-limiting examples: the 5′-cap is selected from the group comprising inverted abasic residue (moiety), 4′,5′-methylene nucleotide; 1-(beta-D-erythrofuranosyl) nucleotide, 4′-thio nucleotide, carbocyclic nucleotide; 1,5-anhydrohexitol nucleotide; L-nucleotides; alpha-nucleotides; modified base nucleotide; phosphorodithioate linkage; threo-pentofuranosyl nucleotide; acyclic 3′,4′-seco nucleotide; acyclic 3,4-dihydroxybutyl nucleotide; acyclic 3,5-dihydroxypentyl nucleotide, 3′-3′-inverted nucleotide moiety; 3′-3′-inverted abasic moiety; 3′-2′-inverted nucleotide moiety; 3′-2′-inverted abasic moiety; 1,4-butanediol phosphate; 3′-phosphoramidate; hexylphosphate; aminohexyl phosphate; 3′-phosphate; 3′-phosphorothioate; phosphorodithioate; or bridging or non-bridging methylphosphonate moiety (for more details see Beigelman et al., International PCT publication No. WO 97/26270, incorporated by reference herein).


[0157] In yet another embodiment, the 3′-cap is selected from a group comprising, 4′,5′-methylene nucleotide; 1-(beta-D-erythrofuranosyl) nucleotide; 4′-thio nucleotide, carbocyclic nucleotide; 5′-amino-alkyl phosphate; 1,3-diamino-2-propyl phosphate, 3-aminopropyl phosphate; 6-aminohexyl phosphate; 1,2-aminododecyl phosphate; hydroxypropyl phosphate; 1,5-anhydrohexitol nucleotide; L-nucleotide; alpha-nucleotide; modified base nucleotide; phosphorodithioate; threo-pentofuranosyl nucleotide; acyclic 3′,4′-seco nucleotide; 3,4-dihydroxybutyl nucleotide; 3,5-dihydroxypentyl nucleotide, 5′-5′-inverted nucleotide moeity; 5′-5′-inverted abasic moeity; 5′-phosphoramidate; 5′-phosphorothioate; 1,4-butanediol phosphate; 5′-amino; bridging and/or non-bridging 5′-phosphoramidate, phosphorothioate and/or phosphorodithioate, bridging or non bridging methylphosphonate and 5′-mercapto moeities (for more details see Beaucage and Iyer, 1993, Tetrahedron 49, 1925; incorporated by reference herein).


[0158] By the term “non-nucleotide” is meant any group or compound which can be incorporated into a nucleic acid chain in the place of one or more nucleotide units, including either sugar and/or phosphate substitutions, and allows the remaining bases to exhibit their enzymatic activity. The group or compound is abasic in that it does not contain a commonly recognized nucleotide base, such as adenosine, guanine, cytosine, uracil or thymine.


[0159] By “nucleotide” as used herein is as recognized in the art to include natural bases (standard), and modified bases well known in the art. Such bases are generally located at the 1′ position of a sugar moiety. A nucleotide generally comprises a base, sugar and a phosphate group. The nucleotide may also be abasic, i.e., lacking a base. The nucleotides can be unmodified or modified at the sugar, phosphate and/or base moiety, (also referred to interchangeably as nucleotide analogs, modified nucleotides, non-natural nucleotides, non-standard nucleotides and other; see for example, Usman and McSwiggen, supra; Eckstein et al., International PCT Publication No. WO 92/07065; Usman et al., International PCT Publication No. WO 93/15187; all hereby incorporated by reference herein). Several examples of modified nucleic acid bases are known in the art and has recently been summarized by Limbach et al., 1994, Nucleic Acids Res. 22, 2183. Some of the non-limiting examples of base modifications that can be introduced into enzymatic nucleic acids without significantly effecting their catalytic activity include, inosine, purine, pyridin-4-one, pyridin-2-one, phenyl, pseudouracil, 2,4,6-trimethoxy benzene, 3-methyl uracil, dihydrouridine, naphthyl, aminophenyl, 5-alkylcytidines (e.g., 5-methylcytidine), 5-alkyluridines (e.g., ribothymidine), 5-halouridine (e.g., 5-bromouridine) or 6-azapyrimidines or 6-alkylpyrimidines (e.g. 6-methyluridine) and others (Burgin et al., 1996, Biochemistry, 35, 14090).


[0160] By “modified bases” in this aspect is meant nucleotide bases other than adenine, guanine, cytosine and uracil at 1′ position or their equivalents; such bases may be used within the catalytic core of the enzyme and/or in the substrate-binding regions.


[0161] By “abasic” is meant sugar moieties lacking a base or having other chemical groups in place of a base at the 1′ position.


[0162] By “unmodified nucleoside” is meant one of the bases adenine, cytosine, guanine, uracil joined to the 1′ carbon of β-D-ribo-furanose.


[0163] By “modified nucleoside” is meant any nucleotide base that contains a modification in the chemical structure of an unmodified nucleotide base, sugar and/or phosphate.


[0164] In connection with 2′-modified nucleotides as described for the present invention, by “amino” is meant 2′-NH2 or 2′-O—NH2, which can be modified or unmodified. Such modified groups are described, for example, in Eckstein et al., U.S. Pat. No. 5,672,695 and Matulic-Adamic et al., WO 98/28317, respectively, which are both incorporated by reference in their entireties.


[0165] Various modifications to nucleic acid (e.g., antisense and ribozyme) structure can be made to enhance the utility of these molecules. Such modifications enhance shelf-life, half-life in vitro, stability, and ease of introduction of such oligonucleotides to the target site, e.g., to enhance penetration of cellular membranes, and confer the ability to recognize and bind to targeted cells.


[0166] Use of these molecules can lead to better treatment of the disease progression by affording the possibility of combination therapies (e.g., multiple enzymatic nucleic acid molecules targeted to different genes, enzymatic nucleic acid molecules coupled with known small molecule inhibitors, or intermittent treatment with combinations of enzymatic nucleic acid molecules (including different ribozyme motifs) and/or other chemical or biological molecules). The treatment of patients with nucleic acid molecules can also include combinations of different types of nucleic acid molecules. Therapies can be devised which include a mixture of enzymatic nucleic acid molecules (including different ribozyme motifs), antisense and/or 2-5A chimera molecules to one or more targets to alleviate symptoms of a disease.


[0167] Administration of Nucleic Acid Molecules


[0168] Sullivan, et al., supra, describes the general methods for delivery of enzymatic RNA molecules. Enzymatic nucleic acid molecules can be administered to cells by a variety of methods known to those familiar to the art, including, but not restricted to, encapsulation in liposomes, by iontophoresis, or by incorporation into other vehicles, such as hydrogels, cyclodextrins, biodegradable nanocapsules, and bioadhesive microspheres. For some indications, enzymatic nucleic acid molecules can be directly delivered ex vivo to cells or tissues with or without the aforementioned vehicles. Alternatively, the nucleic acid/vehicle combination is locally delivered by direct injection or by use of a catheter, infusion pump or stent. Other routes of delivery include, but are not limited to, intravascular, intramuscular, subcutaneous or joint injection, aerosol inhalation, oral (tablet or pill form), topical, systemic, ocular, intraperitoneal and/or intrathecal delivery. More detailed descriptions of nucleic acid delivery and administration are provided in Sullivan et al., supra and Draper et al., supra which have been incorporated by reference herein.


[0169] Methods for the delivery of nucleic acid molecules is described in Akhtar et al., 1992, Trends Cell Bio., 2, 139; and Delivery Strategies for Antisense Oligonucleotide Therapeutics, ed. Akhtar, 1995 which are both incorporated herein by reference. Sullivan et al., PCT WO 94/02595, further describes the general methods for delivery of enzymatic RNA molecules. These protocols can be utilized for the delivery of virtually any nucleic acid molecule. Nucleic acid molecules can be administered to cells by a variety of methods known to those familiar to the art, including, but not restricted to, encapsulation in liposomes, by iontophoresis, or by incorporation into other vehicles, such as hydrogels, cyclodextrins, biodegradable nanocapsules, and bioadhesive microspheres. For some indications, nucleic acid molecules can be directly delivered ex vivo to cells or tissues with or without the aforementioned vehicles. Alternatively, the nucleic acid/vehicle combination is locally delivered by direct injection or by use of a catheter, infusion pump or stent. Other routes of delivery include, but are not limited to, intravascular, intramuscular, subcutaneous or joint injection, aerosol inhalation, oral (tablet or pill form), topical, systemic, ocular, intraperitoneal and/or intrathecal delivery. More detailed descriptions of nucleic acid delivery and administration are provided in Sullivan et al., supra and Draper et al., PCT WO93/23569 which have been incorporated by reference herein.


[0170] The molecules of the instant invention can be used as pharmaceutical agents. Pharmaceutical agents prevent, inhibit the occurrence, or treat (alleviate a symptom to some extent, preferably all of the symptoms) of a disease state in a patient.


[0171] The negatively charged polynucleotides of the invention can be administered (e.g., RNA, DNA or protein) and introduced into a patient by any standard means, with or without stabilizers, buffers, and the like, to form a pharmaceutical composition. When it is desired to use a liposome delivery mechanism, standard protocols for formation of liposomes can be followed. The compositions of the present invention may also be formulated and used as tablets, capsules or elixirs for oral administration; suppositories for rectal administration; sterile solutions; suspensions for injectable administration; and the like.


[0172] The present invention also includes pharmaceutically acceptable formulations of the compounds described. These formulations include salts of the above compounds, e.g., acid addition salts, for example, salts of hydrochloric, hydrobromic, acetic acid, and benzene sulfonic acid.


[0173] A pharmacological composition or formulation refers to a composition or formulation in a form suitable for administration, e.g., systemic administration, into a cell or patient, preferably a human. Suitable forms, in part, depend upon the use or the route of entry, for example oral, transdermal, or by injection. Such forms should not prevent the composition or formulation to reach a target cell (i.e., a cell to which the negatively charged polymer is desired to be delivered to). For example, pharmacological compositions injected into the blood stream should be soluble. Other factors are known in the art, and include considerations such as toxicity and forms which prevent the composition or formulation from exerting its effect.


[0174] By “systemic administration” is meant in vivo systemic absorption or accumulation of drugs in the blood stream followed by distribution throughout the entire body. Administration routes which lead to systemic absorption include, without limitations: intravenous, subcutaneous, intraperitoneal, inhalation, oral, intrapulmonary and intramuscular. Each of these administration routes expose the desired negatively charged polymers, e.g., nucleic acids, to an accessible diseased tissue. The rate of entry of a drug into the circulation has been shown to be a function of molecular weight or size. The use of a liposome or other drug carrier comprising the compounds of the instant invention can potentially localize the drug, for example, in certain tissue types, such as the tissues of the reticular endothelial system (RES). A liposome formulation which can facilitate the association of drug with the surface of cells, such as, lymphocytes and macrophages is also useful. This approach may provide enhanced delivery of the drug to target cells by taking advantage of the specificity of macrophage and lymphocyte immune recognition of abnormal cells, such as the cancer cells.


[0175] The invention also features the use of a composition comprising surface-modified liposomes containing poly (ethylene glycol) lipids (PEG-modified, or long-circulating liposomes or stealth liposomes). These formulations offer a method for increasing the accumulation of drugs in target tissues. This class of drug carriers resists opsonization and elimination by the mononuclear phagocytic system (MPS or RES), thereby enabling longer blood circulation times and enhanced tissue exposure for the encapsulated drug (Lasic et al. Chem. Rev. 1995, 95, 2601-2627; Ishiwata et al., Chem. Pharm. Bull. 1995, 43, 1005-1011). Such liposomes have been shown to accumulate selectively in tumors, presumably by extravasation and capture in the neovascularized target tissues (Lasic et al., Science 1995, 267, 1275-1276; Oku et al., 1995, Biochim. Biophys. Acta, 1238, 86-90). Long-circulating liposomes enhance the pharmacokinetics and pharmacodynamics of DNA and RNA, particularly compared to conventional cationic liposomes which are known to accumulate in tissues of the MPS (Liu et al., J. Biol. Chem. 1995, 42, 24864-24870; Choi et al., International PCT Publication No. WO 96/10391; Ansell et al., International PCT Publication No. WO 96/10390; Holland et al., International PCT Publication No. WO 96/10392; all of these are incorporated by reference herein). Long-circulating liposomes are also likely to protect drugs from nuclease degradation to a greater extent compared to cationic liposomes, based on their ability to avoid accumulation in metabolically aggressive MPS tissues such as the liver and spleen. All of these references are incorporated by reference herein.


[0176] The present invention also includes compositions prepared for storage or administration which include a pharmaceutically effective amount of the desired compounds in a pharmaceutically acceptable carrier or diluent. Acceptable carriers or diluents for therapeutic use are well known in the pharmaceutical art, and are described, for example, in Remington's Pharmaceutical Sciences, Mack Publishing Co. (A. R. Gennaro edit. 1985) hereby incorporated by reference herein. For example, preservatives, stabilizers, dyes and flavoring agents may be provided. Id. at 1449. These include sodium benzoate, sorbic acid and esters of p-hydroxybenzoic acid. In addition, antioxidants and suspending agents can be used. Id.


[0177] A pharmaceutically effective dose is that dose required to prevent, inhibit the occurrence, or treat (alleviate a symptom to some extent, preferably all of the symptoms) of a disease state. The pharmaceutically effective dose depends on the type of disease, the composition used, the route of administration, the type of mammal being treated, the physical characteristics of the specific mammal under consideration, concurrent medication, and other factors which those skilled in the medical arts will recognize. Generally, an amount between 0.1 mg/kg and 100 mg/kg body weight/day of active ingredients is administered dependent upon potency of the negatively charged polymer.


[0178] The nucleic acid molecules of the invention and formulations thereof can be administered orally, topically, parenterally, by inhalation or spray or rectally in dosage unit formulations containing conventional non-toxic pharmaceutically acceptable carriers, adjuvants and vehicles. The term parenteral as used herein includes percutaneous, subcutaneous, intravascular (e.g., intravenous), intramuscular, or intrathecal injection or infusion techniques and the like. In addition, there is provided a pharmaceutical formulation comprising a nucleic acid molecule of the invention and a pharmaceutically acceptable carrier. One or more nucleic acid molecules of the invention can be present in association with one or more non-toxic pharmaceutically acceptable carriers and/or diluents and/or adjuvants, and if desired other active ingredients. The pharmaceutical compositions containing nucleic acid molecules of the invention can be in a form suitable for oral use, for example, as tablets, troches, lozenges, aqueous or oily suspensions, dispersible powders or granules, emulsion, hard or soft capsules, or syrups or elixirs.


[0179] Compositions intended for oral use can be prepared according to any method known to the art for the manufacture of pharmaceutical compositions and such compositions can contain one or more such sweetening agents, flavoring agents, coloring agents or preservative agents in order to provide pharmaceutically elegant and palatable preparations. Tablets contain the active ingredient in admixture with non-toxic pharmaceutically acceptable excipients that are suitable for the manufacture of tablets. These excipients can be for example, inert diluents, such as calcium carbonate, sodium carbonate, lactose, calcium phosphate or sodium phosphate; granulating and disintegrating agents, for example, corn starch, or alginic acid; binding agents, for example starch, gelatin or acacia, and lubricating agents, for example magnesium stearate, stearic acid or talc. The tablets can be uncoated or they can be coated by known techniques. In some cases such coatings can be prepared by known techniques to delay disintegration and absorption in the gastrointestinal tract and thereby provide a sustained action over a longer period. For example, a time delay material such as glyceryl monosterate or glyceryl distearate can be employed.


[0180] Formulations for oral use can also be presented as hard gelatin capsules wherein the active ingredient is mixed with an inert solid diluent, for example, calcium carbonate, calcium phosphate or kaolin, or as soft gelatin capsules wherein the active ingredient is mixed with water or an oil medium, for example peanut oil, liquid paraffin or olive oil.


[0181] Aqueous suspensions contain the active materials in admixture with excipients suitable for the manufacture of aqueous suspensions. Such excipients are suspending agents, for example sodium carboxymethylcellulose, methylcellulose, hydropropyl-methylcellulose, sodium alginate, polyvinylpyrrolidone, gum tragacanth and gum acacia; dispersing or wetting agents can be a naturally-occurring phosphatide, for example, lecithin, or condensation products of an alkylene oxide with fatty acids, for example polyoxyethylene stearate, or condensation products of ethylene oxide with long chain aliphatic alcohols, for example heptadecaethyleneoxycetanol, or condensation products of ethylene oxide with partial esters derived from fatty acids and a hexitol such as polyoxyethylene sorbitol monooleate, or condensation products of ethylene oxide with partial esters derived from fatty acids and hexitol anhydrides, for example polyethylene sorbitan monooleate. The aqueous suspensions can also contain one or more preservatives, for example ethyl, or n-propyl p-hydroxybenzoate, one or more coloring agents, one or more flavoring agents, and one or more sweetening agents, such as sucrose or saccharin.


[0182] Oily suspensions can be formulated by suspending the active ingredients in a vegetable oil, for example arachis oil, olive oil, sesame oil or coconut oil, or in a mineral oil such as liquid paraffin. The oily suspensions can contain a thickening agent, for example beeswax, hard paraffin or cetyl alcohol. Sweetening agents and flavoring agents can be added to provide palatable oral preparations. These compositions can be preserved by the addition of an anti-oxidant such as ascorbic acid.


[0183] Dispersible powders and granules suitable for preparation of an aqueous suspension by the addition of water provide the active ingredient in admixture with a dispersing or wetting agent, suspending agent and one or more preservatives. Suitable dispersing or wetting agents or suspending agents are exemplified by those already mentioned above. Additional excipients, for example sweetening, flavoring and coloring agents, can also be present.


[0184] Pharmaceutical compositions of the invention can also be in the form of oil-in-water emulsions. The oily phase can be a vegetable oil or a mineral oil or mixtures of these. Suitable emulsifying agents can be naturally-occurring gums, for example gum acacia or gum tragacanth, naturally-occurring phosphatides, for example soy bean, lecithin, and esters or partial esters derived from fatty acids and hexitol, anhydrides, for example sorbitan monooleate, and condensation products of the said partial esters with ethylene oxide, for example polyoxyethylene sorbitan monooleate. The emulsions can also contain sweetening and flavoring agents.


[0185] Syrups and elixirs can be formulated with sweetening agents, for example glycerol, propylene glycol, sorbitol, glucose or sucrose. Such formulations can also contain a demulcent, a preservative and flavoring and coloring agents. The pharmaceutical compositions can be in the form of a sterile injectable aqueous or oleaginous suspension. This suspension can be formulated according to the known art using those suitable dispersing or wetting agents and suspending agents that have been mentioned above. The sterile injectable preparation can also be a sterile injectable solution or suspension in a non-toxic parentally acceptable diluent or solvent, for example as a solution in 1,3-butanediol. Among the acceptable vehicles and solvents that can be employed are water, Ringer's solution and isotonic sodium chloride solution. In addition, sterile, fixed oils are conventionally employed as a solvent or suspending medium. For this purpose any bland fixed oil can be employed including synthetic mono- or diglycerides. In addition, fatty acids such as oleic acid find use in the preparation of injectables.


[0186] The nucleic acid molecules of the invention can also be administered in the form of suppositories, e.g., for rectal administration of the drug. These compositions can be prepared by mixing the drug with a suitable non-irritating excipient that is solid at ordinary temperatures but liquid at the rectal temperature and will therefore melt in the rectum to release the drug. Such materials include cocoa butter and polyethylene glycols.


[0187] Nucleic acid molecules of the invention can be administered parenterally in a sterile medium. The drug, depending on the vehicle and concentration used, can either be suspended or dissolved in the vehicle. Advantageously, adjuvants such as local anesthetics, preservatives and buffering agents can be dissolved in the vehicle.


[0188] Dosage levels of the order of from about 0.1 mg to about 140 mg per kilogram of body weight per day are useful in the treatment of the above-indicated conditions (about 0.5 mg to about 7 g per patient per day). The amount of active ingredient that can be combined with the carrier materials to produce a single dosage form varies depending upon the host treated and the particular mode of administration. Dosage unit forms generally contain between from about 1 mg to about 500 mg of an active ingredient.


[0189] It is understood that the specific dose level for any particular patient depends upon a variety of factors including the activity of the specific compound employed, the age, body weight, general health, sex, diet, time of administration, route of administration, and rate of excretion, drug combination and the severity of the particular disease undergoing therapy.


[0190] For administration to non-human animals, the composition can also be added to the animal feed or drinking water. It can be convenient to formulate the animal feed and drinking water compositions so that the animal takes in a therapeutically appropriate quantity of the composition along with its diet. It can also be convenient to present the composition as a premix for addition to the feed or drinking water.


[0191] The nucleic acid molecules of the present invention can also be administered to a patient in combination with other therapeutic compounds to increase the overall therapeutic effect. The use of multiple compounds to treat an indication can increase the beneficial effects while reducing the presence of side effects.


[0192] Another means of accumulating high concentrations of a nucleic acid molecule of the invention (e.g., ribozyme or antisense) within cells is to incorporate the nucleic acid-encoding sequences into a DNA or RNA expression vector. Transcription of the nucleic acid sequences are driven from a promoter for eukaryotic RNA polymerase I (pol I), RNA polymerase II (pol II), or RNA polymerase III (pol III). Transcripts from pol II or pol III promoters will be expressed at high levels in all cells; the levels of a given pol II promoter in a given cell type will depend on the nature of the gene regulatory sequences (enhancers, silencers, etc.) present nearby. Prokaryotic RNA polymerase promoters are also used, providing that the prokaryotic RNA polymerase enzyme is expressed in the appropriate cells (Elroy-Stein and Moss, 1990 Proc. Natl. Acad. Sci. USA, 87, 6743-7; Gao and Huang 1993 Nucleic Acids Res., 21, 2867-72; Lieber et al., 1993 Methods Enzymol., 217, 47-66; Zhou et al., 1990 Mol. Cell. Biol., 10, 4529-37; Thompson et al., 1995 supra). Several investigators have demonstrated that enzymatic nucleic acid or antisese expressed from such promoters can function in mammalian cells (e.g. Izant and Weintraub, 1985 Science 229, 345; McGarry and Lindquist, 1986 Proc. Natl. Acad. Sci. USA 83, 399; Kashani-Sabet et al., 1992 Antisense Res. Dev., 2, 3-15; Ojwang et al., 1992 Proc. Natl. Acad. Sci. USA, 89, 10802-6; Chen et al., 1992 Nucleic Acids Res., 20, 4581-9; Yu et al., 1993 Proc. Natl. Acad. Sci. USA, 90, 6340-4; L'Huillier et al., 1992 EMBO J. 11, 4411-8; Lisziewicz et al., 1993 Proc. Natl. Acad. Sci. U.S. A., 90, 8000-4; Thompson et al., 1995 Nucleic Acids Res. 23, 2259). The above nucleic acid transcription units can be incorporated into a variety of vectors for introduction into mammalian cells, including but not restricted to, plasmid DNA vectors, viral DNA vectors (such as adenovirus or adeno-associated virus vectors), or viral RNA vectors (such as retroviral or alphavirus vectors).


[0193] In one embodiment of the invention, a transcription unit expressing an enzymatic nucleic acid that cleaves RNAs that encode fit-1, KDR and/or flk-1 are inserted into a plasmid DNA vector or an adenovirus or adeno-associated virus DNA viral vector or a retroviral RNA vector. Viral vectors have been used to transfer genes and lead to either transient or long term gene expression (Zabner et al., 1993 Cell 75, 207; Carter, 1992 Curr. Opi. Biotech. 3, 533). The adenovirus, AAV or retroviral vector is delivered as recombinant viral particles. The DNA may be delivered alone or complexed with vehicles (as described for RNA above). The recombinant adenovirus or AAV or retroviral particles are locally administered to the site of treatment, e.g., through incubation or inhalation in vivo or by direct application to cells or tissues ex vivo. Retroviral vectors have also been used to express enzymatic nucleic acid in mammalian cells (Ojwang et al., 1992 supra; Thompson et al., 1995 supra).


[0194] Flt-1, KDR and/or flk-1 are attractive nucleic acid-based therapeutic targets by several criteria. The interaction between VEGF and VEGF-R is well-established. Efficacy can be tested in well-defined and predictive animal models. Finally, the disease conditions are serious and current therapies are inadequate. Whereas protein-based therapies would inhibit VEGF activity nucleic acid-based therapy provides a direct and elegant approach to directly modulate flt-1, KDR and/or flk-1 expression.


[0195] Because flt-1 and KDR mRNAs are highly homologous in certain regions, some enzymatic nucleic acid target sites are also homologous (see Table X). In this case, a single enzymatic nucleic acid cantarget both flt-1 and KDR mRNAs. At partially homologous sites, a single enzymatic nucleic acid can sometimes be designed to accommodate a site on both mRNAs by including G/U base pairing. For example, if there is a G present in an enzymatic nucleic acid target site in KDR mRNA at the same position there is an A in the flt-1 ribozyme target site, the enzymatic nucleic acid can be synthesized with a U at the complementary position and it will bind both to sites. The advantage of one enzymatic nucleic acid that targets both VEGF-R mRNAs is clear, especially in cases where both VEGF receptors may contribute to the progression of angiogenesis in the disease state.


[0196] “Angiogenesis” refers to formation of new blood vessels, which is an essential process in reproduction, development and wound repair. “Tumor angiogenesis” refers to the induction of the growth of blood vessels from surrounding tissue into a solid tumor. Tumor growth and tumor metastasis are dependent on angiogenesis (for a review see Folkman, 1985 supra; Folkman 1990 J. Natl. Cancer Inst., 82, 4; Folkman and Shing, 1992 J. Biol. Chem. 267, 10931).


[0197] Angiogenesis plays an important role in other diseases such as arthritis wherein new blood vessels have been shown to invade the joints and degrade cartilage (Folkinan and Shing, supra).


[0198] “Retinopathy” refers to inflammation of the retina and/or degenerative condition of the retina which may lead to occlusion of the retina and eventual blindness. In “diabetic retinopathy” angiogenesis causes the capillaries in the retina to invade the vitreous resulting in bleeding and blindness which is also seen in neonatal retinopathy (for a review see Folkman, 1985 supra; Folkman 1990 supra; Folkman and Shing, 1992 supra).


[0199] The following examples further illustrate the present invention but should not be construed to limit the present invention in any way.



EXAMPLE 1


flt-1, KDR and/or flk-1 ribozymes

[0200] By engineering ribozyme motifs, Applicant has designed several ribozymes directed against flt-1, KDR and/or flk-1 encoded mRNA sequences. These ribozymes were synthesized with modifications that improve their nuclease resistance (Beigelman et al., 1995 J Biol. Chem. 270, 25702) and enhance their activity in cells. The ability of ribozymes to cleave target sequences in vitro was evaluated essentially as described in Thompson et al., PCT Publication No. WO 93/23057; Draper et al., PCT Publication No. WO 95/04818.



EXAMPLE 2


Effect of Ribozymes on the Binding of VEGF to flt-1, KDR and/or flk-1 Receptors

[0201] Several common human cell lines are available that express endogenous flt-1, KDR and/or flk-1. flt-1, KDR and/or flk-1 which can be detected easily with monoclonal antibodies. Use of appropriate fluorescent reagents and fluorescence-activated cell-sorting (FACS) permit direct quantitation of surface flt-1, KDR and/or fik-1 on a cell-by-cell basis. Active ribozymes are expected to directly reduce flt-1, KDR and/or flk-1 expression and thereby reduce VEGF binding to the cells. In this example, human umbelical cord microvascular endothelial cells were used.


[0202] Cell Preparation


[0203] Plates were coated with 1.5% gelatin and allowed to stand for one hour. Cells (e.g., microvascular endothelial cells derived from human umbilical cord vein) were plated at 20,000 cells/well (24 well plate) in 200 μl growth media and incubated overnight (˜1 doubling) to yield ˜40,000 cells (75-80% confluent).


[0204] Ribozyme Treatment


[0205] Media was removed from cells and the cells were washed two times with 300 μl 1× PBS:Ca2+:Mg2+ mixture. A complex of 200-500 nM ribozyme and LipofectAMINE® (3:1 lipid:phosphate ratio) in 200 μl OptiMEM® (5% FBS) was added to the cells. The cells were incubated for 6 hr (equivalent to 2-3 VEGF-R turnovers).


[0206]

125
I VEGF Binding Assay


[0207] The assay was carried out on ice to inhibit internalization of VEGF during the experiment. The media containing the ribozyme was removed from the cells and the cells were washed twice with 300 μl 1× PBS: Ca2+:Mg2+ mixture containing 1% BSA. Appropriate 125I VEGF solution (100,000 cpm/well, +/−10× cold 1× PBS, 1% BSA) was applied to the cells. The cells were incubated on ice for 1 hour. 125I VEGF-containing solution was removed and the cells were washed three times with 300 μl 1× PBS: Ca2+: Mg2+ mixture containing 1% BSA. To each well 300 μl of 100 mM Tris-HCl, pH 8.0, 0.5% Triton X-100 was added and the mixture was incubated for 2 minutes. The 125I VEGF-binding was quantitated using standard scintillation counting techniques. Percent inhibition was calculated as follows:
1PercentInhibition=cpm125IVEGFboundbytheribozyme-treatedsamplescpm125IVEGFboundbytheControlsample×100



EXAMPLE 3


Effect of Hammerhead Ribozymes Targeted Against flt-1 Receptor on the Binding of VEGF

[0208] Hammerhead ribozymes targeted to twenty sites within flt-1 RNA were synthesized as described above. The sequences of the ribozymes used are shown in Table II; the length of the stem II region is 3 bp. The hammerhead ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic ribose.


[0209] Referring to FIG. 7, the effect of hammerhead ribozymes targeted against flt-1 receptor on the binding of VEGF to flt-1 on the surface of human microvascular endothelial cells is shown. The majority of the ribozymes tested were able to inhibit the expression of flt-1 and thereby were able to inhibit the binding of VEGF.


[0210] In order to determine the specificity of ribozymes targeted against flt-1 RNA, the effect of five anti-flt-1 ribozymes on the binding of VEGF, UPA (urokinase plasminogen activator) and FGF (fibroblast growth factor) to their corresponding receptors were assayed. As shown in FIG. 9, there was significant inhibition of VEGF binding to its receptors on cells treated with anti-flt-1 ribozymes. There was no specific inhibition of the binding of UPA and FGF to their corresponding receptors. These data strongly suggest that anti-flt-1 ribozymes specifically cleave flt-1 RNA and not RNAs encoding the receptors for UPA and FGF, resulting in the inhibition of flt-1 receptor expression on the surface of the cells. Thus the ribozymes are responsible for the inhibition of VEGF binding but not the binding of UPA and FGF.



EXAMPLE 4


Effect of Hammerhead Ribozymes Targeted Against KDR Receptor on the Binding of VEGF

[0211] Hammerhead ribozymes targeted to twenty-one sites within KDR RNA were synthesized as described above. The sequences of the ribozymes used are shown in Table IV; the length of stem II region is 3 bp. The hammerhead ribozymes were chemically modified such that the ribozyme consists of ribose residues at five positions; U4 and U7 positions contain 2′-NH2 modifications, the remaining nucleotide positions contain 2′-O-methyl substitutions; four nucleotides at the 5′ terminus contains phosphorothioate substitutions. Additionally, the 3′ end of the ribozyme contains a 3′-3′ linked inverted abasic deoxyribose.


[0212] Referring to FIG. 8, the effect of hammerhead ribozymes targeted against KDR receptor on the binding of VEGF to KDR on the surface of human microvascular endothelial cells is shown. A majority of the ribozymes tested were able to inhibit the expression of KDR and thereby were able to inhibit the binding of VEGF. As a control, the cells were treated with a ribozyme that is not targeted towards KDR RNA (irrel. RZ); there was no specific inhibition of VEGF binding. The results from this control experiment strongly suggest that the inhibition of VEGF binding observed with anti-KDR ribozymes is a ribozyme-mediated inhibition.



EXAMPLE 5


Effect of Ribozymes Targeted Against VEGF Receptors on Cell Proliferation

[0213] Cell Preparation


[0214] 24-well plates were coated with 1.5% gelatin (porcine skin 300 bloom). After 1 hour, excess gelatin is washed off of the plate. Microvascular endothelial cells were plated at 5,000 cells/well (24 well plate) in 200 μl growth media. The cells were allowed to grow for 18 hours (˜1 doubling) to yield ˜10,000 cells (25-30% confluent).


[0215] Ribozyme Treatment


[0216] Media was removed from the cells, and the cells were washed two times with 300 μl 1× PBS: Ca2+: Mg2+ mixture.


[0217] For anti-flt-1HH ribozyme experiment (FIG. 12) a complex of 500 nM ribozyme; 15 μM LFA (3:1 lipid:phosphate ratio) in 200 μl OptiMEM (5% FCS) media was added to the cells. Incubation of cells was carried out for 6 hours (equivalent to 2-3 VEGF receptor turnovers).


[0218] For anti-KDR HH ribozyme experiment (FIG. 13) a complex of 200 nM ribozyme; 5.25 μM LFA (3:1 lipid:phosphate ratio) in 200 μl OptiMEM (5% FCS) media was added to the cells. Incubation of cells was carried out for 3 hours.


[0219] Proliferation


[0220] After three or six hours, the media was removed from the cells and the cells were washed with 300 μl 1× PBS: Ca2+: Mg2+ mixture. Maintenance media (contains dialyzed 10% FBS) +/−VEGF or basic FGF at 10 ng/ml was added to the cells. The cells were incubated for 48 or 72 hours. The cells were trypsinized and counted (Coulter counter). Trypan blue was added on one well of each treatment as a control.


[0221] As shown in FIG. 12B, VEGF and basic FGF stimulate human microvascular endothelial cell proliferation. However, treatment of cells with 1358 HH or 4229 HH ribozymes, targeted against flt-1 mRNA, results in a significant decrease in the ability of VEGF to stimulate endothelial cell proliferation. These ribozymes do not inhibit the FGF-mediated stimulation of endothelial cell proliferation.


[0222] Human microvascular endothelial cells were also treated with hammerhead ribozymes targeted against sites 527, 730, 3702 or 3950 within the KDR mRNA. As shown in FIG. 13, all four ribozymes caused significant inhibition of VEGF-mediated induction of cell proliferation. No significant inhibition of cell proliferation was observed when the cells were treated with a hammerhead ribozyme targeted to an irrelevant RNA. Additionally, none of the ribozymes inhibited FGF-mediated stimulation of cell proliferation.


[0223] These results strongly suggest that hammerhead ribozymes targeted against either flt-1 or KDR mRNA specifically inhibit VEGF-mediated induction of endothelial cell proliferation.



EXAMPLE 6


Effect of Antisense Oligonucleotides Targeted Against VEGF Receptors on Cell Proliferation (Colorimetric Assay)

[0224] The following are some of the reagents used in the proliferation assay:


[0225] Cells: Human aortic endothelial cells (HAEC) from Clonetics®. Cells at early passage are preferably used.


[0226] Uptake Medium: EBM (from Clonetics®); 1% L-Glutamine; 20 mM Hepes; No serum; No antibiotics.


[0227] Growth Medium: EGM (from Clonetics®); FBS to 20%; 1% L-Glutamine; 20 mM Hepes.


[0228] Cell Plating: 96-well tissue culture plates were coated with 0.2% gelatin (50 μl/well). The gelatin was incubated in the wells at room temperature for 15-30 minutes. The gelatin was removed by aspiration and the wells were washed with PBS:Ca2+: Mg2+ mixture. PBS mixture was left in the wells until cells were ready to be added. HAEC cells were detached by trypsin treatment and resuspended at 1.25×104/ml in growth medium. PBS was removed from plates and 200 μl of cells (i.e. 2.5×103 cells/well) were added to each well. The cells were allowed to grow for 48 hours before the proliferation assay.


[0229] Assay: Growth medium was removed from the wells. The cells were washed twice with PBS:Ca2+: Mg2+ mixture without antibiotics. A formulation of lipid/antisense oligonucleotide (antisense oligonucleotide is used here as a non-limiting example) complex was added to each well (100 μl/well) in uptake medium. The cells were incubated for 2-3 hours at 37° C. in a CO2 incubator. After uptake, 100 μl/well of growth medium was added (gives final FBS concentration of 10%). After approximately 72 hours, 40 μl MTS® stock solution (made as described by manufacturer) was added to each well and incubated at 37° C. for 1-3 hours, depending on the color development. (For this assay, 2 hours was sufficient). The intensity of color formation was determined on a plate reader at 490 nM.


[0230] Phosphorothioate-substituted antisense oligodeoxynucleotides were custom synthesized by The Midland Certified Reagent Company®, Midland, Tex. Following non-limiting antisense oligodeoxynucleotides targeted against KDR RNA were used in the proliferation assay:
1KDR 21 AS:5′-GCA GCA CCT TGC TCT CCA TCC-3′SCRAMBLED CONTROL:5′-CTG CCA ACT TCC CAT GCC TGC-3′


[0231] As shown in FIG. 10, proliferation of HAEC cells is specifically inhibited by increasing concentrations of the phosphorothioate anti-KDR-antisense oligodeoxynucleotide. The scrambled antisense oligonucleotide is not expected to bind the KDR RNA and therefore is not expected to inhibit KDR expression. As expected, there is no detectable inhibition of proliferation of HAEC cells treated with a phosphorothioate antisense oligonucleotide with scrambled sequence.



EXAMPLE 7


In vitro Cleavage of flt-1 RNA by Hammerhead Ribozymes

[0232] Referring to FIG. 11A, hammerhead ribozymes (HH) targeted against sites 1358 and 4229 within the flt-1 RNA were synthesized as described above.


[0233] RNA Cleavage Assay In Vitro


[0234] Substrate RNA was 5′ end-labeled using [γ-32P] ATP and T4 polynucleotide kinase (US Biochemicals). Cleavage reactions were carried out under ribozyme “excess” conditions. Trace amount (≦1 nM) of 5′ end-labeled substrate and 40 nM unlabeled ribozyme were denatured and renatured separately by heating to 90° C. for 2 minutes and snap-cooling on ice for 10-15 minutes. The ribozyme and substrate were incubated, separately, at 37° C. for 10 minutes in a buffer containing 50 mM Tris-HCl and 10 mM MgCl2. The reaction was initiated by mixing the ribozyme and substrate solutions and incubating at 37° C. Aliquots of 5 μl were taken at regular intervals of time and the reaction was quenched by mixing with equal volume of 2× formamide stop mix. The samples were resolved on 20% denaturing polyacrylamide gels. The results were quantified and percentage of target RNA cleaved is plotted as a function of time.


[0235] Referring to FIGS. 11B and 11C, hammerhead ribozymes targeted against sites 1358 and 4229 within the flt-1 RNA are capable of cleaving target RNA efficiently in vitro.



EXAMPLE 8


In vitro Cleavage of KDR RNA by Hammerhead Ribozymes

[0236] In this non-limiting example, hammerhead ribozymes targeted against sites 726, 527, 3702 and 3950 within KDR RNA were synthesized as described above. RNA cleavage reactions were carried out in vitro essentially as described under Example 7.


[0237] Referring to FIGS. 14 and 15, all four ribozymes were able to cleave their cognate target RNA efficiently in a sequence-specific manner.



EXAMPLE 9


In vitro Cleavage of RNA by Hammerhead Ribozymes Targeted Against Cleavage Sites that are Homologous Between KDR and flt-1 mRNA

[0238] Given that flt-1 and KDR mRNAs are highly homologous in certain regions, some ribozyme target sites are also homologous (see Table X). In this case, a single ribozyme will target both flt-1 and KDR mRNAs. Hammerhead ribozyme (FLT/KDR-1) targeted against one of the homologous sites between flt-1 and KDR (flt-1 site 3388 and KDR site 3151) was synthesized as described above. Ribozymes with either a 3 bp stem II or a 4 bp stem II were synthesized. RNA cleavage reactions were carried out in vitro essentially as described under Example 7.


[0239] Referring to FIG. 16, FLT/KDR-I ribozyme with either a 3 or a 4 bp stem II was able to cleave its target RNA efficiently in vitro.



EXAMPLE 10


Effect of Multiple Ribozymes Targeted Against Both flt-1 and KDR RNA on Cell Proliferation

[0240] Since both flt-1 and KDR receptors of VEGF are involved in angiogenesis, the inhibition of the expression of both of these genes can be an effective approach to inhibit angiogenesis.


[0241] Human microvascular endothalial cells were treated with hammerhead ribozyrnes targeted against sites flt-1 4229 alone, KDR 527 alone, KDR 726 alone, KDR 3950 alone, flt-1 4229+KDR 527, flt-1 4229+KDR 726 or flt-1 4229+KDR 3950. As shown in FIG. 17, all the combinations of active ribozymes (A) caused significant inhibition of VEGF-mediated induction of cell proliferation. No significant inhibition of cell proliferation was observed when the cells were treated with a catalytically inactive (I) hammerhead ribozymes. Additionally, cells treated with ribozymes targeted against both flt-1 and KDR RNAs-flt-1 4229+KDR 527; flt-1 4229+KDR 726; flt-1 4229+KDR 3950, were able to cause a greater inhibition of VEGF-mediated induction of cell proliferation when compared with individual ribozymes targeted against either flt-1 or KDR RNA (see flt-1 4229 alone; KDR 527 alone; KDR 726 alone; KDR 3950 alone). This strongly suggests that treatment of cells with multiple ribozymes can be a more effective means of inhibition of gene expression.


[0242] Animal Models


[0243] There are several animal models in which the anti-angiogenesis effect of nucleic acids of the present invention, such as enzymatic nucleic acids, directed against VEGF-R mRNAs can be tested. Typically a corneal model has been used to study angiogenesis in rat and rabbit since recruitment of vessels can easily be followed in this normally avascular tissue (Pandey et al., 1995 Science 268: 567-569). In these models, a small Teflon or Hydron disk pretreated with an angiogenesis factor (e.g. bFGF or VEGF) is inserted into a pocket surgically created in the cornea. Angiogenesis is monitored 3 to 5 days later. Enzymatic nucleic acids directed against VEGF-R mRNAs are delivered in the disk as well, or dropwise to the eye over the time course of the experiment. In another eye model, hypoxia has been shown to cause both increased expression of VEGF and neovascularization in the retina (Pierce et al., 1995 Proc. Natl. Acad. Sci. USA. 92: 905-909; Shweiki et al., 1992 J. Clin. Invest. 91: 2235-2243).


[0244] In human glioblastomas, it has been shown that VEGF is at least partially responsible for tumor angiogenesis (Plate et al., 1992 Nature 359, 845). Animal models have been developed in which glioblastoma cells are implanted subcutaneously into nude mice and the progress of tumor growth and angiogenesism is studied (Kim et al., 1993 supra; Millauer et al., 1994 supra).


[0245] Another animal model that addresses neovascularization involves Matrigel, an extract of basement membrane that becomes a solid gel when injected subcutaneously (Passaniti et al., 1992 Lab. Invest. 67: 519-528). When the Matrigel is supplemented with angiogenesis factors such as VEGF, vessels grow into the Matrigel over a period of 3 to 5 days and angiogenesis can be assessed. Again, nucleic acids directed against VEGF-R mRNAs are delivered in the Matrigel.


[0246] Several animal models exist for screening of anti-angiogenic agents. These include corneal vessel formation following corneal injury (Burger et al., 1985 Cornea 4: 35-41; Lepri, et al., 1994 J. Ocular Pharmacol. 10: 273-280; Ormerod et al., 1990 Am. J. Pathol. 137: 1243-1252) or intracorneal growth factor implant (Grant et al., 1993 Diabetologia 36: 282-291; Pandey et al. 1995 supra; Zieche et al., 1992 Lab. Invest. 67: 711-715), vessel growth into Matrigel matrix containing growth factors (Passaniti et al., 1992 supra), female reproductive organ neovascularization following hormonal manipulation (Shweiki et al., 1993 Clin. Invest. 91: 2235-2243), several models involving inhibition of tumor growth in highly vascularized solid tumors (O'Reilly et al., 1994 Cell 79: 315-328; Senger et al., 1993 Cancer and Metas. Rev. 12: 303-324; Takahasi et al., 1994 Cancer Res. 54: 4233-4237; Kim et al., 1993 supra), and transient hypoxia-induced neovascularization in the mouse retina (Pierce et al., 1995 Proc. Natl. Acad. Sci. USA. 92: 905-909).


[0247] The cornea model, described in Pandey et al. supra, is the most common and well characterized anti-angiogenic agent efficacy screening model. This model involves an avascular tissue into which vessels are recruited by a stimulating agent (growth factor, thermal or alkalai burn, endotoxin). The corneal model utilizes the intrastromal corneal implantation of a Teflon pellet soaked in a VEGF-Hydron solution to recruit blood vessels toward the pellet which can be quantitated using standard microscopic and image analysis techniques. To evaluate their anti-angiogenic efficacy, nucleic acids are applied topically to the eye or bound within Hydron on the Teflon pellet itself. This avascular cornea as well as the Matrigel (see below) provide for low background assays. While the corneal model has been performed extensively in the rabbit, studies in the rat have also been conducted.


[0248] The mouse model (Passaniti et al., supra) is a non-tissue model which utilizes Matrigel, an extract of basement membrane (Kleinman et al., 1986) or Millipore® filter disk, which can be impregnated with growth factors and anti-angiogenic agents in a liquid form prior to injection. Upon subcutaneous administration at body temperature, the Matrigel or Millipore® filter disk forms a solid implant. VEGF embedded in the Matrigel or Millipore® filter disk is used to recruit vessels within the matrix of the Matrigel or Millipore® filter disk which can be processed histologically for endothelial cell specific vWF (factor VIII antigen) immunohistochemistry, Trichrome-Masson stain, or hemoglobin content. Like the cornea, the Matrigel or Millipore® filter disk are avascular; however, it is not tissue. In the Matrigel or Millipore® filter disk model, nucleic acids are administered within the matrix of the Matrigel or Millipore® filter disk to test their anti-angiogenic efficacy. Thus, delivery issues in this model, as with delivery of nucleic acids by Hydron-coated Teflon pellets in the rat cornea model, may be less problematic due to the homogeneous presence of the nucleic acid within the respective matrix.


[0249] These models offer a distinct advantage over several other angiogenic models listed previously. The ability to use VEGF as a pro-angiogenic stimulus in both models is highly desirable since the instant nucleic acid molecules target only VEGFr mRNA. In other words, the involvement of other non-specific types of stimuli in the cornea and Matrigel models is not advantageous from the standpoint of understanding the pharmacologic mechanism by which the anti-VEGFr mRNA nucleic acid molecules produce their effects. In addition, the models allow for testing the specificity of the anti-VEGFr mRNA nucleic acids by using either a- or bFGF as a pro-angiogenic factor. Vessel recruitment using FGF should not be affected in either model by anti-VEGFr mRNA nucleic acid molecules. Other models of angiogenesis including vessel formation in the female reproductive system using hormonal manipulation (Shweiki et al., 1993 supra); a variety of vascular solid tumor models which involve indirect correltations with angiogenesis (O'Reilly et al., 1994 supra; Senger et al., 1993 supra; Takahasi et al., 1994 supra; Kim et al., 1993 supra); and retinal neovascularization following transient hypoxia (Pierce et al., 1995 supra) were not selected for efficacy screening due to their non-specific nature, although there is a correlation between VEGF and angiogenesis in these models.


[0250] Other model systems to study tumor angiogenesis is reviewed by Folkman, 1985 Adv. Cancer. Res. 43, 175.


[0251] Use of Murine Models


[0252] For a typical systemic study involving 10 mice (20 g each) per dose group, 5 doses (1, 3, 10, 30 and 100 mg/kg daily over 14 days continuous administration), approximately 400 mg of enzymatic nucleic acid, formulated in saline is used. A similar study in young adult rats (200 g) requires over 4 g. Parallel pharmacokinetic studies involve the use of similar quantities of enzymatic nucleic acid further justifying the use of murine models.


[0253] Enzymatic Nucleic Acids and Lewis Lung Carcinoma and B-16 Melanoma Murine Models


[0254] Identifying a common animal model for systemic efficacy testing of enzymatic nucleic acid is an efficient way of screening enzymatic nucleic acid for systemic efficacy.


[0255] The Lewis lung carcinoma and B-16 murine melanoma models are well accepted models of primary and metastatic cancer and are used for initial screening of anti-cancer agents. These murine models are not dependent upon the use of immunodeficient mice, are relatively inexpensive, and minimize housing concerns. Both the Lewis lung and B-16 melanoma models involve subcutaneous implantation of approximately 106 tumor cells from metastatically aggressive tumor cell lines (Lewis lung lines 3LL or D122, LLc-LN7; B-16-BL6 melanoma) in C57BL/6J mice. Alternatively, the Lewis lung model can be produced by the surgical implantation of tumor spheres (approximately 0.8 mm in diameter). Metastasis also can be modeled by injecting the tumor cells directly intravenously. In the Lewis lung model, microscopic metastases can be observed approximately 14 days following implantation with quantifiable macroscopic metastatic tumors developing within 21-25 days. The B-16 melanoma exhibits a similar time course with tumor neovascularization beginning 4 days following implantation. Since both primary and metastatic tumors exist in these models after 21-25 days in the same animal, multiple measurements can be taken as indices of efficacy. Primary tumor volume and growth latency as well as the number of micro- and macroscopic metastatic lung foci or number of animals exhibiting metastases can be quantitated. The percent increase in lifespan can also be measured. Thus, these models provide suitable primary efficacy assays for screening systemically administered enzymatic nucleic acids and enzymatic nucleic acid formulations.


[0256] In the Lewis lung and B-16 melanoma models, systemic pharmacotherapy with a wide variety of agents usually begins 1-7 days following tumor implantation/inoculation with either continuous or multiple administration regimens. Concurrent pharmacokinetic studies can be performed to determine whether sufficient tissue levels of ribozymes can be achieved for pharmacodynamic effect to be expected. Furthermore, primary tumors and secondary lung metastases can be removed and subjected to a variety of in vitro studies (i.e. target RNA reduction).


[0257] Flt-1, KDR and/or flk-1 protein levels can be measured clinically or experimentally by FACS analysis. Flt-1, KDR and/or flk-1 encoded mRNA levels are assessed by Northern analysis, RNase-protection, primer extension analysis and/or quantitative RT-PCR. Enzymatic nucleic acids that block flt-1, KDR and/or flk-1 protein encoding mRNAs and therefore result in decreased levels of flt-1, KDR and/or flk-1 activity by more than 20% in vitro can be identified.


[0258] Enzymatic nucleic acids and/or genes encoding them are delivered by either free delivery, liposome delivery, cationic lipid delivery, adeno-associated virus vector delivery, adenovirus vector delivery, retrovirus vector delivery or plasmid vector delivery in these animal model experiments (see above).


[0259] Patients can be treated by locally administering nucleic acids targeted against VEGF-R by direct injection. Routes of administration include, but are not limited to, intravascular, intramuscular, subcutaneous, intraarticular, aerosol inhalation, oral (tablet, capsule or pill form), topical, systemic, ocular, intraperitoneal and/or intrathecal delivery.



EXAMPLE 11


Ribozyme-Mediated Inhibition of Angiogenesis in vivo

[0260] The purpose ot this study was to assess the anti-angiogenic activity of hammerhead ribozymes targeted against flt-1 4229 site in the rat cornea model of VEGF induced angiogenesis (see above). These ribozymes have either active or inactive catalytic core and either bind and cleave or just bind to VEGF-R mRNA of the flt-1 subtype. The active ribozymes, that are able to bind and cleave the target RNA, have been shown to inhibit (125I-labeled) VEGF binding in cultured endothelial cells and produce a dose-dependent decrease in VEGF induced endothelial cell proliferation in these cells (see Examples 3-5 above). The catalytically inactive forms of these ribozymes, wherein the ribozymes can only bind to the RNA but cannot catalyze RNA cleavage, fail to show these characteristics. The ribozymes and VEGF were co-delivered using the filter disk method: Nitrocellulose filter disks (Millipore®) of 0.057 diameter were immersed in appropriate solutions and were surgically implanted in rat cornea as described by Pandey et al., supra. This delivery method has been shown to deliver rhodamine-labeled free ribozyme to scleral cells and, in all likelihood cells of the pericorneal vascular plexus. Since the active ribozymes show cell culture efficacy and can be delivered to the target site using the disk method, it is essential that these ribozymes be assessed for in vivo anti-angiogenic activity.


[0261] The stimulus for angiogenesis in this study was the treatment of the filter disk with 30 μM VEGF which is implanted within the cornea's stroma. This dose yields reproducible neovascularization stemming from the pericorneal vascular plexus growing toward the disk in a dose-response study 5 days following implant. Filter disks treated only with the vehicle for VEGF show no angiogenic response. The ribozymes were co-adminstered with VEGF on a disk in two different ribozyme concentrations. One concern with the simultaneous administration is that the ribozymes will not be able to inhibit angiogenesis since VEGF receptors can be stimulated. However, Applicant has observed that in low VEGF doses, the neovascular response reverts to normal suggesting that the VEGF stimulus is essential for maintaining the angiogenic response. Blocking the production of VEGF receptors using simultaneous administration of anti-VEGF-R mRNA ribozymes could attenuate the normal neovascularization induced by the filter disk treated with VEGF.
2Materials and Methods:1.Stock hammerhead ribozyme solutions:a. fit-1 4229 (786 μM)-Activeb. fit-1 4229 (736 μM)-Inactive2.Experimantal solutions/groups:Group 1Solution 1Control VEGF solution: 30 μM in 82 mM Tris baseGroup 2Solution 2fit-1 4229 (1 μg/μL) in 30 μM VEGF/82 mMTris baseGroup 3Solution 3fit-1 4229 (10 μg/μL) in 30 μM VEGF/82 mMTris baseGroup 4Solution 4No VEGF, fit-1 4229 (10 μg/μL) in 82 mMTris baseGroup 5Solution 5No VEGF, No ribozyme in 82 mM Tris base10 eyes per group, 5 animals (Since they have similar molecular weights, the molar concentrations should be essentially similar).


[0262] Each solution (VEGF and RIBOZYMES) were prepared as a 2×solution for 1:1 mixing for final concentrations above, with the exception of solution 1 in which VEGF was 2× and diluted with ribozyme diluent (sterile water).


[0263] 3. VEGF Solutions


[0264] The 2× VEGF solution (60 μM) was prepared from a stock of 0.82 μg/μL in 50 mM Tris base. 200 μL of VEGF stock was concentrated by speed vac to a final volume of 60.8 μL, for a final concentration of 2.7 μg/μL or 60 μM. Six 10 μL aliquots were prepared for daily mixing. 2×solutions for VEGF and Ribozyme was stored at 4° C. until the day of the surgery. Solutions were mixed for each day of surgery. Original 2× solutions were prepared on the day before the first day of the surgery.
34.Surgical Solutions:Anesthesia:stock ketamine hydrochloride 100 mg/mLstock xylazine hydrochloride 20 mg/mLstock acepromazine 10 mg/mLFinal anesthesia solution: 50 mg/mL ketamine, 10 mg/mL xylazine,and 0.5 mg/mL acepromazine5% povidone iodine for opthalmic surgical wash2% lidocaine (sterile) for opthalmic administration (2 drops per eye)sterile 0.9% NaCl for opthalmic irrigation


[0265] 5. Surgical Methods


[0266] Standard surgical procedure was performed as described in Pandey et al., supra. Filter disks were incubated in 1 μL of each solution for approximately 30 minutes prior to implantation.


[0267] 6. Experimental Protocol


[0268] The animal corneas were treated with the treatment groups as described above. Animals were allowed to recover for 5 days after treatment with daily observation (scoring 0-3). On the fifth day animals were euthanized and digital images of each eye was obtained for quantitaion using Image Pro Plus. Quantitated neovascular surface areas were analyzed by ANOVA followed by two post-hoc tests including Dunnets and Tukey-Kramer tests for significance at the 95% confidence level. Dunnets provide information on the significance between the differences within the means of treatments vs. controls while Tukey-Kramer provide information on the significance of differences within the means of each group.


[0269] Results are graphically represented in FIG. 18. As shown in FIG. 18, flt-1 4229 active hammerhead ribozyme at both concentrations was effective at inhibiting angiogenesis, while the inactive ribozyme did not show any significant reduction in angiogenesis. A statistically signifiant reduction in neovascular surface area was observed only with active ribozymes. This result clearly shows that the ribozymes are capable of significantly inhibiting angiogenesis in vivo. Specifically, the mechanism of inhibition appears to be by the binding and cleavage of target RNA by ribozymes.



EXAMPLE 12


Bioactivity of Anti-Angiogenesis Ribozymes Targeting flt-1 and kdr RNA

[0270] Materials and Methods


[0271] Ribozymes: Hammerhead ribozymes and controls designed to have attenuated activity (attenuated controls) were synthesized and purified as previously described above. The attenuated ribozyme controls maintain the binding arm sequence of the parent ribozyme and thus are still capable of binding to the mRNA target. However, they have two nucleotide changes in the core sequence that substantially reduce their ability to carry out the cleavage reaction. Ribozymes were designed to target Flt-1 or KDR mRNA sites conserved in human, mouse, and rat. In general, ribozymes with binding arms of seven nucleotides were designed and tested. If, however, only six nucleotides surrounding the cleavage site were conserved in all three species, six nucleotide binding arms were used. A subset of ribozyme and attenuated control sequences and modifications are listed in Table XII. Data are presented herein for 2′-NH2 uridine modified ribozymes in cell proliferation studies and for 2′-C-allyl uridine modified ribozymes in RNAse protection, in vitro cleavage and corneal studies.


[0272] In vitro ribozyme cleavage assays: In vitro RNA cleavage rates on a 15 nucleotide synthetic RNA substrate were measured as previously described above.


[0273] Cell culture: Human dermal microvascular endothelial cells (HMVEC-d, Clonetics Corp.) were maintained at 37° C. in flasks or plates coated with 1.5% porcine skin gelatin (300 bloom, Sigma) in Growth medium (Clonetics Corp.) supplemented with 10-20% fetal bovine serum (FBS, Hyclone). Cells were grown to confluency and used up to the seventh passage. Stimulation medium consisted of 50% Sigma 99 media and 50% RPMI 1640 with L-glutamine and additional supplementation with 10 μg/mL Insulin-Transferrin-Selenium (Gibco BRL) and 10% FBS. Cell growth was stimulated by incubation in Stimulation medium supplemented with 20 ng/mL of either VEGF165 or bFGF. VEGF165 (165 amino acids) was selected for cell culture and animal studies because it is the predominant form of the four native forms of VEGF generated by alternative mRNA splicing. Cell culture assays were carried out in triplicate.


[0274] Ribozyme and Ribozyme/LIPOFECTAMINE™ Formulations:


[0275] Cell culture: Ribozymes or attenuated controls (50-200 nM) were formulated for cell culture studies and used immediately. Formulations were carried out with LIPOFECTAMINE™ (Gibco BRL) at a 3:1 lipid to phosphate charge ratio in serum-free medium (OPTI-MEM™, Gibco BRL) by mixing for 20 minutes at room temperature. For example, a 3:1 lipid to phosphate charge ratio was established by complexing 200 nM ribozyme with 10.8 μg/μL LIPOFECTAMINE™ (13.5 μM DOSPA).


[0276] In vivo: For corneal studies, lyophilized ribozyme or attenuated controls were resuspended in sterile water at a final stock concentration of 170 μg/μL (highest dose). Lower doses (1.7-50 μg/μL) were prepared by serial dilution in sterile water.


[0277] Proliferation assay: HMVEC-d were seeded (5×103 cells/well) in 48-well plates (Costar) and incubated 24-30 hours in Growth medium at 37° C. After removal of the Growth medium, cells were treated with 50-200 DM LIPOFECTAMINE™ complexes of ribozyrne or attenuated controls for 2 hours in OPTI-MEM™. The ribozyme/control-containing medium was removed and the cells were washed extensively in 1× PBS. The medium was then replaced with Stimulation medium or Stimulation medium supplemented with 20 ng/mL VEGF165 or bFGF. After 48 hours, the cell number was determined using a Coulter™ cell counter. Data are presented as cell number per well following 48 h of VEGF stimulation.


[0278] RNAse protection assay: HMVEC-d were seeded (2×105 cells/well) in 6-well plates (Costar) and allowed to grow 32-36 hours in Growth medium at 37° C. Cells were treated with LIPOFECTAMINE™ complexes containing 200 nM ribozyme or attenuated control for 2 hours as described under “Proliferation Assay” and then incubated in Growth medium containing 20 ng/mL VEGF165 for 24 hours. Cells were harvested and an RNAse protection assay was carried out using the Ambion Direct Protect kit and protocol with the exception that 50 mM EDTA was added to the lysis buffer to eliminate the possibility of ribozyme cleavage during sample preparation. Antisense RNA probes targeting portions of Flt-1 and KDR were prepared by transcription in the presence of [32P]-UTP. Samples were analyzed on polyacrylamide gels and the level of protected RNA fragments was quantified using a Molecular Dynamics Phosphorlmager. The levels of Flt-1 and KDR were normalized to the level of cyclophilin (human cyclophilin probe template, Ambion) in each sample. The coefficient of variation for cyclophilin levels was 11% [265940 cpm±29386 (SD)] for all conditions tested here (i.e. in the presence of either active ribozymes or attenuated controls). Thus, cyclophilin is useful as an internal standard in these studies.


[0279] Rat Corneal Pocket Assay of VEGF-Induced Angiogenesis


[0280] Animal guidelines and anesthesia. Animal housing and experimentation adhered to standards outlined in the 1996 Guide for the Care and Use of Laboratory Animals (National Research Council). Male Sprague Dawley rats (250-300 g) were anesthetized with ketamine (50 mg/kg), xylazine (10 mg/kg), and acepromazine (0.5 mg/kg) administered intramuscularly (im). The level of anesthesia was monitored every 2-3 min by applying hind limb paw pressure and examining for limb withdrawal. Atropine (0.4 mg/kg, im) was also administered to prevent potential corneal reflex-induced bradycardia.


[0281] Preparation of VEGF soaked disk. For corneal implantation, 0.57 mm diameter nitrocellulose disks, prepared from 0.45 μm pore diameter nitrocellulose filter membranes (Millipore Corporation), were soaked for 30 min in 1 μL of 30 μM VEGF165 in 82 mM Tris HCl (pH 6.9) in covered petri dishes on ice.


[0282] Corneal surgery. The rat corneal model used in this study was a modified from Koch et al. Supra and Pandey et al., supra. Briefly, corneas were irrigated with 0.5% povidone iodine solution followed by normal saline and two drops of 2% lidocaine. Under a dissecting microscope (Leica MZ-6), a stromal pocket was created and a presoaked filter disk (see above) was inserted into the pocket such that its edge was 1 mm from the corneal limbus.


[0283] Intraconjunctival injection of test solutions. Immediately after disk insertion, the tip of a 40-50 μm OD injector (constructed in our laboratory) was inserted within the conjunctival tissue 1 mm away from the edge of the corneal limbus that was directly adjacent to the VEGF-soaked filter disk. Six hundred nanoliters of test solution (ribozyme, attenuated control or sterile water vehicle) were dispensed at a rate of 12 μL/min using a syringe pump (Kd Scientific). The injector was then removed, serially rinsed in 70% ethanol and sterile water and immersed in sterile water between each injection. Once the test solution was injected, closure of the eyelid was maintained using microaneurism clips until the animal began to recover gross motor activity. Following treatment, animals were warmed on a heating pad at 37° C.


[0284] Animal treatment groups/experimental protocol. Ribozymes targeting Flt-1 site 4229 and KDR mRNA site 726 were tested in the corneal model along with their attenuated controls. Five treatment groups were assigned to examine the effects of five doses of each test substance over a dose range of 1-100 μg on VEGF-stimulated angiogenesis. Negative (30 μM VEGF soaked filter disk and intraconjunctival injection of 600 nL sterile water) and no stimulus (Tris-soaked filter disk and intraconjunctival injection of sterile water) control groups were also included. Each group consisted of five animals (10 eyes) receiving the same treatment.


[0285] Quantitation of angiogenic response. Five days after disk implantation, animals were euthanized following im administration of 0.4 mg/kg atropine and corneas were digitally imaged. The neovascular surface area (NSA, expressed in pixels) was measured postmortem from blood-filled corneal vessels using computerized morphometry (Inage Pro Plus, Media Cybernetics, v2.0). The individual mean NSA was determined in triplicate from three regions of identical size in the area of maximal neovascularization between the filter disk and the limbus. The number of pixels corresponding to the blood-filled corneal vessels in these regions was summated to produce an index of NSA. A group mean NSA was then calculated. Data from each treatment group were normalized to VEGF/ribozyme vehicle-treated control NSA and finally expressed as percent inhibition of VEGF-induced angiogenesis.


[0286] Statistics. After determining the normality of treatment group means, group mean percent inhibition of VEGF-induced angiogenesis was subjected to a one-way analysis of variance. This was followed by two post-hoc tests for significance including Dunnett's (comparison to VEGF control) and Tukey-Kramer (all other group mean comparisons) at alpha=0.05. Statistical analyses were performed using JMP v.3.1.6 (SAS Institute).


[0287] Results


[0288] Ribozyme-mediated reduction of VEGF-induced cell proliferation: Ribozyme cleavage of Flt-1 or KDR mRNA should result in a decrease in the density of cell surface VEGF receptors. This decrease should limit VEGF binding and consequently interfere with the mitogenic signaling induced by VEGF. To determine if cell proliferation was impacted by anti-Flt-1 and/or anti-KDR ribozyme treatment, proliferation assays using cultured human microvascular cells were carried out. Ribozymes included in the proliferation assays were initially chosen by their ability to decrease the level of VEGF binding to treated cells (see FIG. 8). In these initial studies, ribozymes targeting 20 sites in the coding region of each mRNA were screened. The most effective ribozymes against two sites in each target (Table XII), Flt-1 sites 1358 and 4229 and KDR sites 726 and 3950, were included in the proliferation assays reported here (FIG. 19). In addition, attenuated analogs of each ribozyme were used as controls (Table XII). These attenuated controls are still capable of binding to the mRNA target since the binding arm sequence is maintained. However, these controls have two nucleotide changes in the core sequence that substantially reduce their ability to carry out the cleavage reaction.


[0289] The antiproliferative effect of active ribozymes targeting two lead sites on each VEGF receptor mRNA is shown in FIG. 19. The active ribozymes tested decreased the relative proliferation of HMVEC-d after VEGF stimulation, an effect that increased with ribozyme concentration. This concentration dependency was not observed following treatment with the attenuated controls designed for these sites. In fact, little or no change in cell growth was noted following treatment with the attenuated controls, even though these controls can still bind to the specific target sequences. At 200 nM, there was a distinct “window” between the anti-proliferative effects of each ribozyme and its attenuated control; a trend also observed at lower doses. This window of inhibition of proliferation (56-77% based on total cells/well) reflects the contribution of ribozyme-mediated activity. In comparison, no effect of anti-Flt-1 or anti-KDR ribozymes was noted on bFGF-stimulated cell proliferation (FIGS. 19C, 19F). Moreover, an irrelevant, but active, ribozyine whose binding sequence is not found in either Flt-1 or KDR mRNA had no effect in this assay (FIG. 19B). These data are consistent with the basic ribozyme mechanism in which binding and cleavage are necessary components. Although the relative surface distribution of Flt-1 and KDR receptors in this cell type is not known, the antiproliferative effects of these ribozymes indicate that, at least in cell culture, both receptors are functionally coupled to proliferation.


[0290] Specific reduction of Fit-1 or KDR mRNA by ribozyme treatment: To confirm that anti-Flt-1 and anti-KDR ribozymes reduce their respective mRNA targets, cellular levels of Flt-1 or KDR were quantified using an RNAse protection assay with specific Flt-1 or KDR probes. For each target, one ribozyme/attenuated control pair was chosen for continued study. Data from a representative experiment are shown in FIG. 20. Exposure of HMVEC-d to active ribozyme targeting Flt-1 site 4229 decreased Flt-1 mRNA, but not KDR mRNA. Likewise, treatment with the active ribozyme targeting KDR site 726 decreased KDR, but not Flt-1 mRNA. Both ribozymes decreased the level of their respective target RNA by greater than 50%. The degree of reduction associated with the corresponding attenuated controls was not greater than 13%.


[0291] In vitro Activity of Anti-Flt and Anti-KDR Ribozymes


[0292] To confirm further the necessity of an active ribozyme core, in vitro cleavage activities were determined for the Flt-1 site 4229 ribozyme and the KDR site 726 ribozyme as well as their paired attenuated controls. The first order rate constants calculated from the time-course of short substrate cleavage for the anti-Flt-1 ribozyme and its attenuated control were 0.081+0.0007 min−1 and 0.001±6×10−5 min−1, respectively. For the anti-KDR ribozyme and its paired control, the first order rate constants were 0.434±0.024 min−1 and 0.002±1×10−4 min−1, respectively. Although the attenuated controls retain a very slight level of cleavage activity under these optimized conditions, the decrease in in vitro cleavage activity between each active ribozyme and its paired attenuated control is about two orders of magnitude. Thus, an active core is essential for cleavage activity in vitro and is also necessary for ribozyme activity in cell culture.


[0293] Ribozyme-mediated reduction of VEGF-induced angiogenesis in vivo. To assess whether ribozymes targeting VEGF receptor mRNA could impact the complex process of angiogenesis, prototypic anti-Flt-1 and KDR ribozymes that were identified in cell culture studies were screened in a rat corneal pocket assay of VEGF-induced angiogenesis. In this assay, corneas implanted with VEGF-containing filter disks exhibited a robust neovascular response in the corneal region between the disk and the corneal limbus (from which the new vessels emerge). Disks containing a vehicle solution elicited no angiogenic response. In separate studies, intraconjunctival injections of sterile water vehicle did not affect the magnitude of the VEGF-induced angiogenic response. In addition, ribozyme injections alone did not induce angiogenesis.


[0294] The dose-related effects of anti-Flt-1 or KDR ribozymes on the VEGF-induced angiogenic response were then examined. FIGS. 21 and 22 illustrate the quantified antiangiogenic effect of the anti-Flt-1 (site 4229) and KDR (site 726) ribozymes and their attenuated controls over a dose range from 1 to 100 μg, respectively. For both ribozymes, the maximal antiangiogenic response (48 and 36% for anti-Flt-1 and KDR ribozymes, respectively) was observed at a dose of 10 μg.


[0295] The anti-Flt-1 ribozyme produced a significantly greater antiangiogenic response than its attenuated control at 3 and 10 μg (p<0.05; FIG. 21). Its attenuated control exhibited a small but significant antiangiogenic response at doses above 10 μg compared to vehicle treated VEGF controls (p<0.05; FIG. 21). At its maximum, this response was not significantly greater than that observed with the lowest dose of active anti-Flt-1 ribozyme. The anti-KDR ribozyme significantly inhibited angiogenesis from 3 to 30 μg (p<0.05; FIG. 22). The anti-KDR attenuated control had no significant effect at any dose tested.



EXAMPLE 13


In Vivo Inhibition of Tumor Growth and Metastases by VEGF-R Ribozymes

[0296] A. Lewis Lung Carcinoma Mouse Model: Ribozymes were chemically synthesized as described above. The sequence of ANGIOZYME™ bound to its target RNA is shown in FIG. 26.


[0297] The tumors in this study were derived from a cell line (LLC-HM) which gives rise to reproducible numbers of spontaneous lung metastases when propagated in vivo. The LLC-HM line was obtained from Dr. Michael O'Reilly, Harvard University. Tumor neovascularization in Lewis lung carcinoma has been shown to be VEGF-dependent. Tumors from mice bearing LLC-HM (selected for the highly metastatic phenotype by serial propagation) were harvested 20 days post-inoculation. A tumor brei suspension was prepared from these tumors according to standard protocols. On day 0 of the study, 0.5×106 viable LLC-HM tumor cells were injected subcutaneously (sc) into the dorsum or flank of previously untreated mice (100 μL injectate). Tumors were allowed to grow for a period of 3 days prior to initiating continuous intravenous administration of saline or 30 mg/kg/d ANGIOZYME™ via Alzet mini-pumps. One set of animals was dosed from days 3 to 17, inclusive. Tumor length and width measurements and volumes were calculated according to the formula: Volume=0.5(length)(width)2. At post-inoculation day 25, animals were euthanized and lungs harvested. The number of lung macrometastatic nodules was counted. It should be noted that metastatic foci were quantified 8 days after the cessation of dosing. Ribozyme solutions were prepared to deliver to another set of animals 100, 10, 3, or 1 mg/kg/day of ANGIOZYME™ via Alzet mini-pumps. A total of 10 animals per dose or saline control group were surgically implanted on the left flank with osmotic mini-pumps pre-filled with the respective test solution three days following tumor inoculation. Pumps were attached to indwelling jugular vein catheters.


[0298]
FIG. 27 shows the antitumor effects of ANGIOZYME™. There is a statistically significant inhibition (p<0.05) of primary LLC-HM tumor growth in tumors grown in the flank regions compared to saline control. ANGIOZYME™ significantly reduced (p<0.05) the number of lung metastatic foci in animals inoculated either in the flank regions. FIG. 28 illustrates the dose-dependent anti-metastatic effect of ANGIOZYME™ compared to saline control.


[0299] B. Mouse Colorectal Cancer Model. KM12L4a-16 is a human colorectal cancer cell line. On day 0 of the study, 0.5×106 KM12L4a-16 cells were implanted into the spleen of nude mice. Three days after tumor inoculation, Alzet minipumps were implanted and continuous subcutaneous delivery of either saline or 12, 36 or 100 mg/kg/day of ANGIOZYME™ was initiated. On day 5, the spleens containing the primary tumors were removed. On day 18, the Alzet minipumps were replaced with fresh pumps so that delivery of saline or ANGIOZYME™ was continuous over a 28 day period from day 3 to day 32. Animals were euthanized on day 41 and the liver tumor burden was evaluated.


[0300] Following treatment with 100 mg/kg/day of ANGIOZYME™, there was a significant reduction in the incidence and median number of liver metastasis (FIGS. 29 and 30). In saline-treated animals, the median number of metastases was 101. However, at the high dose of ANGIOZYME™ (100 mg/kg/day), the median number of metastases was zero.



EXAMPLE 14


Effect of ANGIOZYME™ Alone or in Combination with Chemotherapeutic Agents in the Mouse Lewis Lung Carcinoma Model

[0301] Methods


[0302] Tumor inoculations. Male C57/BL6 mice, age 6 to 8 weeks, were inoculated subcutaneously in the flank with 5×105 LLC-HM cells from brei preparations made from tumors grown in mice.


[0303] Ribozymes and controls. The ribozyme and controls tested in this study are given in Table XIII. RPI.4610, also known as ANGIOZYME™, is an anti-Flt-1 ribozyme that targets site 4229 in the human Flt-1 receptor mRNA (EMBL accession no. X51602). The controls tested include RPI.13141, an attenuated version of RPI.4610 in which four nucleotides in the catalytic core are changed so that the cleavage activity is dramatically decreased. RPI.13141, however, maintains the base composition and binding arms of RPI.4610 and so is still capable of binding to the target site. The second control (RPI.13030) also has changes to the catalytic core (three) to inhibit cleavage activity, but in addition the sequence of the binding arms has been scrambled so that it can no longer bind to the target sequence. One nucleotide in the arm of RPI.13030 is also changed to maintain the same base composition as RPI.4610.


[0304] Ribozyme administrations. Ribozymes and controls were resuspended in normal saline. Administration was initiated seven days following tumor inoculation. Animals either received a daily subcutaneous injection (30 mg/kg test substance) from day 7 to day 20 or were instrumented with an Alzet osmotic minipump (12 μL/day flow rate) containing a solution of ribozyme or control. Subcutaneous infusion pumps delivered the test substances (30 mg/kg/day) from day 7 to 20 (14-day pumps, 420 mg/kg total test substance) or days 7-34 (28-day pumps, 840 mg/kg total test substance). Where indicated, chemotherapeutic agents were given in combination with ribozyme treatment. Cyclophosphamide was given by ip administration on days 7, 9 and 11 (125 mg/kg). Gemcitabine was given by intraperitoneal administration on days 8, 11 and 14 (125 mg/kg). Untreated, uninstrumented animals were used as comparison. Five animals were included in each group.


[0305] Results


[0306] The antiangiogenic ribozyme, ANGIOZYME™, was tested in a model of Lewis lung carcinoma alone and in combination with two chemotherapeutic agents. Previously (see above), 30 mg/kg/day ANGIOZYME™ alone was determined to inhibit both primary tumor growth and lung metastases in a highly metastatic variant of Lewis lung (continuous 14-day intraveneous delivery via Alzet minipump).


[0307] In this study, 30 mg/kg/day ANGIOZYME™ delivered either as a daily subcutaneous bolus injection or as a continuous infusion from an Alzet minipump resulted in a delay in tumor growth (FIG. 23). On average, tumor growth to 500 mm3 was delayed by approximately 7 days in animals being treated with ANGIOZYME™ compared to an untreated group. Growth of tumors in animals being treated with either of two attenuated controls was delayed by only approximately 2 days.


[0308] ANGIOZYME™ delivered by subcutaneous bolus was also tested in combination with either Gemcytabine or cyclophosphamide (FIG. 24). Tumor growth delay increased by about 3 days in the presence of combination therapy with ANGIOZYME™ and Gemcytabine over the effects of either treatment alone. The combination of ANGIOZYME™ and cyclophosphamide did not increase tumor growth delay over that of cyclophosphamide alone, however, suboptimal doses of cyclophosphamide were not included in this study. Neither of the attenuated controls increased the effect of the chemotherapeutic agents.


[0309] The effect of ANGIOZYME™ on metastases to the lung was also determined in the presence and absence of additional chemotherapeutic treatment. Macrometastases to the lungs were counted in two animals in each treatment group on day 20. Data for the daily subcutaneous administration of 30 mg/kg ANGIOZYME™ alone or with Gemcytabine or cyclophosphamide is given in FIG. 25. In the presence of ANGIOZYME™, with or without a chemotherapeutic agent, the lung metastases were reduced to zero. Treatment with either Gemcytabine or cyclophosphamide alone (mean number of metastases 4.5 and 4, respectively) were not as effective as ANGIOZYME™ alone or when used in combination with ANGIOZYME™. Neither of the attenuated controls increased the effect of the chemotherapeutic agents.


[0310] The effect on metastases to the lung was also determined following continuous treatment with ANGIOZYME™. At day 20, an average of approximately 8 macrometastases were noted in the treatment groups which had been instrumented with Alzet minipumps (either 14- or 28-day pumps). This is a decrease in metastases of approximately 50% from the untreated group. Since ANGIOZYME™ delivered by a daily subcutaneous bolus resulted in zero metastases (FIG. 4) in the two animals counted, it is possible that the additional burden of being instrumented with the minipump contributes to a slightly decreased response to ANGIOZYME™.



EXAMPLE 15


Phase I/II Study of Repetitive Dose ANGIOZYME™ Targeting the FLT-1 Receptor of VEGF

[0311] A ribozyme therapeutic agent ANGIOZYME™, was assessed by daily subcutaneous administration in a phase I/II trial for 31 patients with refractory solid tumors. Demographic information relating to patients enrolled in the study are shown in Table XX. The primary study endpoint was to determine the safety and maximum tolerated dose of ANGIOZYME™. Secondary endpoints assessed ANGIOZYME™ pharmacokinetics and clinical response. Patients were treated in four cohorts of three patients at doses of 10, 30, 100, and 300 mg/m2/day. Following the dose escalation phase, an additional 15 evaluable patients were entered in an expanded cohort at 100 mg/m2/day. Patients were dosed for a minimum of 29 consecutive days with 24-hour pharmacokinetic analyses on Day 1 and 29. Clinical response was assessed monthly.


[0312] Results


[0313] The data from 20 patients indicated that ANGIOZYME™ was well tolerated, with no systemic adverse events. FIG. 31 shows the plasma concentration profile of ANGIOZYME™ after a single SC (sub-cutaneous) dose of 10, 30, 100, or 300 mg/m2. The pharmacokinetic parameters of ANGIOZYME™ after SC bolus administration are outlined in Table XXI. An MTD (maximum tolerated dose) could not be established. One patient in the 300 mg/m2/d group experienced a grade 3 injection site reaction. Patients in the other groups experienced intermittent grade 1 and grade 2 injection site reactions with erythema and induration. No systemic or laboratory toxicities were observed. Pharmacokinetic analyses demonstrated dose-dependent plasma concentrations with good bioavailability (70-90%), t1/2=209-384 min, and no accumulation after repeated doses. To date, 17/28 (61%) of evaluable patients have had stable disease for periods of one to six months and two patients (nasopharyngeal squamous cell carcinoma and melanoma) had minor clinical responses. The patient with nasopharyngeal carcinoma demonstrated central tumor necrosis as indicated by MRI. The longest period of treatment thus far has been 8 months for two patients at 100 mg/m2/d (breast, peritoneal mesothelioma).



EXAMPLE 16


In vivo Inhibition of Neovascularization in an Ocular Animal Model by VEGF-R Ribozymes

[0314] Summary of the Mouse Model: A mouse model of proliferative retinopathy (Aiello et al., 1995, Proc. Natl. Acad. Sci. USA 92: 10457-10461; Robinson et al., 1996, Proc. Natl. Acad. Sci. USA 93: 4851-4856; Pierce et al., 1996, Archives of Ophthalmology 114: 1219-1228) in which neovascularization of the mouse retina is induced by exposure of 7-day old mice to 75% oxygen followed by a return to normal room air. The initial period in high oxygen causes an obliteration of developing blood vessels in the retina. Exposure to room air five days later is perceived as hypoxia by the now underperfused retina. The result is an immediate upregulation of VEGF mRNA and VEGF protein (between 6-12 hours) followed by an extensive retinal neovascularization that peaks in approximately 5 days. Although this model is more representative of retinopathy of prematurity than diabetic retinopathy, it is an accepted small animal model in which to study neovascular pathophysiology of the retina. In fact, intravitreal injection of certain antisense DNA constructs targeting VEGF mRNA have been found to be antiangiogenic in this model, as were soluble VEGF receptor chimeric proteins designed to bind VEGF in the vitreous humor (Aiello et al., 1995, Proc. Natl. Acad. Sci. USA 92: 10457-10461; Robinson et al., 1996, Proc. Natl. Acad. Sci. USA 93: 4851-4856; Pierce et al., 1996, Archives of Ophthalmology 114: 1219-1228).


[0315] Summary of experiment: The effect of an anti-KDR/Flk-1 ribozyme on the peak level of neovascularization was tested in the mouse model described above. As shown in FIG. 34A, P7 mice were removed from the hyperoxic chamber and the mice received two intraocular injections (P12 and P13) in the right eye of 10 μg RPI.4731, the anti-KDR/Flk-1 ribozyme. The left eye of each mouse was treated as a control and received intraocular injections of saline. Five days after being exposed to room air, neovascular nuclei in the retina of both eyes were counted. Data are presented in FIG. 34B. There was a significant decrease in retinal neovascularization (approximately 40%) compared to the control, saline-injected eyes.


[0316] RPI.4731 sequence and chemical composition:


[0317] 5′-usascs asau ucU GAu Gag gcg aaa gcc Gaa Aag aca aB-3′ (SEQ ID NO: 13488)


[0318] where: uppercase G, A=ribonucleotides


[0319] lowercase=2′-OMe


[0320] U=2′-C-allyl uridine


[0321] B=inverted abasic nucleotide


[0322] S=phosphorothioate linkage


[0323] Indications


[0324] 1) Tumor angiogenesis: Angiogenesis has been shown to be necessary for tumors to grow into pathological size (Folkman, 1971, PNAS 76, 5217-5221; Wellstein & Czubayko, 1996, Breast Cancer Res and Treatment 38, 109-119). In addition, it allows tumor cells to travel through the circulatory system during metastasis. Increased levels of gene expression of a number of angiogenic factors such as vascular endothelial growth factor (VEGF) have been reported in vascularized and edema-associated brain tumors (Berkman et al., 1993 J. Clini. Invest. 91, 153). A more direct demonstration of the role of VEGF in tumor angiogenesis was demonstrated by Jim Kim et al., 1993 Nature 362,841 wherein, monoclonal antibodies against VEGF were successfully used to inhibit the growth of rhabdomyosarcoma, glioblastoma multiforme cells in nude mice. Similarly, expression of a dominant negative mutated form of the flt-1 VEGF receptor inhibits vascularization induced by human glioblastoma cells in nude mice (Millauer et al., 1994, Nature 367, 576). Specific tumor/cancer types that can be targeted using the nucleic acid molecules of the invention include but are not limited to the tumor/cancer types described under Diagnosis in Table XX.


[0325] 2) Ocular diseases: Neovascularization has been shown to cause or exacerbate ocular diseases including but not limited to, macular degeneration, neovascular glaucoma, diabetic retinopathy, myopic degeneration, and trachoma (Norrby, 1997, APMIS 105, 417-437). Aiello et al., 1994 New Engl. J. Med. 331, 1480, showed that the ocular fluid, of a majority of patients suffering from diabetic retinopathy and other retinal disorders, contains a high concentration of VEGF. Miller et al., 1994 Am. J. Pathol. 145, 574, reported elevated levels of VEGF mRNA in patients suffering from retinal ischemia. These observations support a direct role for VEGF in ocular diseases. Other factors, including those that stimulate VEGF synthesis, may also contribute to these indications.


[0326] 3) Dermatological Disorders: Many indications have been identified which may be angiogenesis dependent including, but not limited to, psoriasis, verruca vulgaris, angiofibroma of tuberous sclerosis, pot-wine stains, Sturge Weber syndrome, Kippel-Trenaunay-Weber syndrome, and Osler-Weber-Rendu syndrome (Norrby, supra). Intradermal injection of the angiogenic factor b-FGF demonstrated angiogenesis in nude mice (Weckbecker et al., 1992, Angiogenesis: Key principles-Science-Technology-Medicine, ed R. Steiner) Detmar et al., 1994 J. Exp. Med. 180, 1141 reported that VEGF and its receptors were over-expressed in psoriatic skin and psoriatic dermal microvessels, suggesting that VEGF plays a significant role in psoriasis.


[0327] 4) Rheumatoid arthritis: Immunohistochemistry and in situ hybridization studies on tissues from the joints of patients suffering from rheumatoid arthritis show an increased level of VEGF and its receptors (Fava et al., 1994 J. Exp. Med. 180, 341). Additionally, Koch et al., 1994 J. Immunol. 152, 4149, found that VEGF-specific antibodies were able to significantly reduce the mitogenic activity of synovial tissues from patients suffering from rheumatoid arthritis. These observations support a direct role for VEGF in rheumatoid arthritis. Other angiogenic factors including those of the present invention may also be involved in arthritis.


[0328] Combination Therapies


[0329] Gemcytabine and cyclophosphamide are non-limiting examples of chemotherapeutic agents that can be combined with or used in conjunction with the nucleic acid molecules (e.g. ribozyrnes and antisense molecules) of the instant invention. Those skilled in the art will recognize that other anti-angiogenic and/or anti-cancer compounds and therapies can be similarly be readily combined with the nucleic acid molecules of the instant invention (e.g. ribozymes and antisense molecules) and are hence within the scope of the instant invention. Such compounds and therapies are well known in the art (see for example Cancer: Principles and Pranctice of Oncology, Volumes 1 and 2, eds Devita, V. T., Hellman, S., and Rosenberg, S. A., J. B. Lippincott Company, Philadelphia, USA; incorporated herein by reference) and include, without limitations, folates, antifolates, pyrimidine analogs, fluoropyrimidines, purine analogs, adenosine analogs, topoisomerase I inhibitors, anthrapyrazoles, retinoids, antibiotics, anthacyclins, platinum analogs, alkylating agents, nitrosoureas, plant derived compounds such as vinca alkaloids, epipodophyllotoxins, tyrosine kinase inhibitors, taxols, radiation therapy, surgery, nutritional supplements, gene therapy, radiotherapy, for example 3D-CRT, immunotoxin therapy, for example ricin, and monoclonal antibodies. Specific examples of chemotherapeutic compounds that can be combined with or used in conjuction with the nucleic acid molecules of the invention include, but are not limited to, Paclitaxel; Docetaxel; Methotrexate; Doxorubin; Edatrexate; Vinorelbine; Tomaxifen; Leucovorin; 5-fluoro uridine (5-FU); Ionotecan; Cisplatin; Carboplatin; Amsacrine; Cytarabine; Bleomycin; Mitomycin C; Dactinomycin; Mithramycin; Hexamethylmelamine; Dacarbazine; L-asperginase; Nitrogen mustard; Melphalan, Chlorambucil; Busulfan; Ifosfamide; 4-hydroperoxycyclophosphamide, Thiotepa; Irinotecan (CAMPTOSAR®, CPT-11, Camptothecin-11, Campto) Tamoxifen, Herceptin; IMC C225; ABX-EGF: and combinations thereof.


[0330] Diagnostic Uses


[0331] The nucleic acid molecules of this invention (e.g., enzymatic nucleic acid) can be used as diagnostic tools to examine genetic drift and mutations within diseased cells or to detect the presence of flt-1, KDR and/or flk-1 RNA in a cell. The close relationship between enzymatic nucleic acid activity and the structure of the target RNA allows the detection of mutations in any region of the molecule which alters the base-pairing and three-dimensional structure of the target RNA. By using multiple enzymatic nucleic acids described in this invention, one can map nucleotide changes which are important to RNA structure and function in vitro, as well as in cells and tissues. Cleavage of target RNAs with enzymatic nucleic acid can be used to inhibit gene expression and define the role (essentially) of specified gene products in the progression of disease. In this manner, other genetic targets can be defined as important mediators of the disease. These experiments can lead to better treatment of the disease progression by affording the possibility of combinational therapies (e.g., multiple enzymatic nucleic acids targeted to different genes, enzymatic nucleic acids coupled with known small molecule inhibitors, or intermittent treatment with combinations of enzymatic nucleic acids and/or other chemical or biological molecules). Other in vitro uses of enzymatic nucleic acids of the invention are well known in the art, and include detection of the presence of mRNAs associated with flt-1, KDR and/or flk-1 related condition. Such RNA is detected by determining the presence of a cleavage product after treatment with a ribozyme using standard methodology.


[0332] In a specific example, enzymatic nucleic acids which can cleave only wild-type or mutant forms of the target RNA are used for the assay. The first enzymatic nucleic acid is used to identify wild-type RNA present in the sample and the second enzymatic nucleic acid is used to identify mutant RNA in the sample. As reaction controls, synthetic substrates of both wild-type and mutant RNA are cleaved by both enzymatic nucleic acids to demonstrate the relative enzymatic nucleic acid efficiencies in the reactions and the absence of cleavage of the “non-targeted” RNA species. The cleavage products from the synthetic substrates also serve to generate size markers for the analysis of wild-type and mutant RNAs in the sample population. Thus, each analysis requires two enzymatic nucleic acids, two substrates and one unknown sample which is combined into six reactions. The presence of cleavage products is determined using an RNAse protection assay so that full-length and cleavage fragments of each RNA can be analyzed in one lane of a polyacrylamide gel. It is not absolutely required to quantify the results to gain insight into the expression of mutant RNAs and putative risk of the desired phenotypic changes in target cells. The expression of mRNA whose protein product is implicated in the development of the phenotype (i.e., flt-1, KDR and/or flk-1) is adequate to establish risk. If probes of comparable specific activity are used for both transcripts, then a qualitative comparison of RNA levels is adequate and decreases the cost of the initial diagnosis. Higher mutant form to wild-type ratios is correlated with higher risk whether RNA levels are compared qualitatively or quantitatively. The use of enzymatic nucleic acid molecules in diagnostic applications contemplated by the instant invention is more fully described in George et al., U.S. Pat. Nos. 5,834,186 and 5,741,679, Shih et al., U.S. Pat. No. 5,589,332, Nathan et al., U.S. Pat. No. 5,871,914, Nathan and Ellington, International PCT publication No. WO 00/24931, Breaker et al., International PCT Publication Nos. WO 00/26226 and 98/27104, and Sullenger et al., International PCT publication No. WO 99/29842.


[0333] Additional Uses


[0334] Potential usefulness of sequence-specific enzymatic nucleic acid molecules of the instant invention have many of the same applications for the study of RNA that DNA restriction endonucleases have for the study of DNA (Nathans et al., 1975 Ann. Rev. Biochem. 44:273). For example, the pattern of restriction fragments can be used to establish sequence relationships between two related RNAs, and large RNAs can be specifically cleaved to fragments of a size more useful for study. The ability to engineer sequence specificity of the enzymatic nucleic acid molecule is ideal for cleavage of RNAs of unknown sequence. Applicant describes the use of nucleic acid molecules to down-regulate gene expression of target genes in bacterial, microbial, fungal, viral, and eukaryotic systems including plant, or mammalian cells.


[0335] All patents and publications mentioned in the specification are indicative of the levels of skill of those skilled in the art to which the invention pertains. All references cited in this disclosure are incorporated by reference to the same extent as if each reference had been incorporated by reference in its entirety individually.


[0336] One skilled in the art would readily appreciate that the present invention is well adapted to carry out the objects and obtain the ends and advantages mentioned, as well as those inherent therein. The methods and compositions described herein as presently representative of preferred embodiments are exemplary and are not intended as limitations on the scope of the invention. Changes therein and other uses will occur to those skilled in the art, which are encompassed within the spirit of the invention, are defined by the scope of the claims.


[0337] It will be readily apparent to one skilled in the art that varying substitutions and modifications may be made to the invention disclosed herein without departing from the scope and spirit of the invention. Thus, such additional embodiments are within the scope of the present invention and the following claims.


[0338] The invention illustratively described herein suitably may be practiced in the absence of any element or elements, limitation or limitations which is not specifically disclosed herein. Thus, for example, in each instance herein any of the terms “comprising”, “consisting essentially of” and “consisting of” may be replaced with either of the other two terms. The terms and expressions which have been employed are used as terms of description and not of limitation, and there is no intention that in the use of such terms and expressions of excluding any equivalents of the features shown and described or portions thereof, but it is recognized that various modifications are possible within the scope of the invention claimed. Thus, it should be understood that although the present invention has been specifically disclosed by preferred embodiments, optional features, modification and variation of the concepts herein disclosed may be resorted to by those skilled in the art, and that such modifications and variations are considered to be within the scope of this invention as defined by the description and the appended claims.


[0339] In addition, where features or aspects of the invention are described in terms of Markush groups or other grouping of alternatives, those skilled in the art will recognize that the invention is also thereby described in terms of any individual member or subgroup of members of the Markush group or other group.


[0340] Other embodiments are within the claims that follow.
4TABLE ICharacteristics of RibozymesGroup I IntronsSize: ˜200 to >1000 nucleotides.Requires a U in the target sequence immediately 5′ of the cleavagesite.Binds 4-6 nucleotides at 5′ side of cleavage site.Over 75 known members of this class. Found in Tetrahymenathermophila rRNA, fungal mitochondria, chloroplasts, phage T4,blue-green algae, and others.RNAseP RNA (M1 RNA)Size: ˜290 to 400 nucleotides.RNA portion of a ribonucleoprotein enzyme. Cleaves tRNAprecursors to form mature tRNA.Roughly 10 known members of this group all are bacterial in origin.Hammerhead RibozymeSize: ˜13 to 40 nucleotides.Requires the target sequence UH immediately 5′ of the cleavagesite.Binds a variable number of nucleotides on both sides of thecleavage site.14 known members of this class. Found in a number of plantpathogens (virusoids) that use RNA as the infectious agent (FIGS. 1and 2)Hairpin RibozymeSize: ˜50 nucleotides.Requires the target sequence GUC immediately 3′ of the cleavagesite.Binds 4-6 nucleotides at 5′ side of the cleavage site and a variablenumber to the 3′ side of the cleavage site.Only 3 known member of this class. Found in three plant pathogen(satellite RNAs of the tobacco ringspot virus, arabis mosaic virusand chicory yellow mottle virus) which uses RNA as the infectiousagent (FIG. 3).Hepatitis Delta Virus (HDV) RibozymeSize: 50-60 nucleotides (at present).Sequence requirements not fully determined.Binding sites and structural requirements not fully determined,although no sequences 5′ of cleavage site are required.Only 1 known member of this class. Found in human HDV (FIG.4).Neuraspora VS RNA RibozymeSize: ˜144 nucleotides (at present)Cleavage of target RNAs recently demonstrated.Sequence requirements not fully determined.Binding sites and structural requirements not fully determined. Only1 known member of this class. Found in Neurospora VS RNA(FIG. 5).


[0341]

5





TABLE II










Human flt1 VEGF Receptor—Hammerhead Ribozyme and Substrate Sequence













Seq ID

Seq ID


Pos
Substrate
No
HH Ribozyme
No














10
CGGACACUC CUCUCGGC
1
GCCGAGAG CUGAUGAGGCCGUUAGGCCGAA AGUGUCCG
9420


13
ACACUCCUC UCGGCUCC
2
GGAGCCGA CUGAUGAGGCCGUUAGGCCGAA AGGAGUGU
9421


15
ACUCCUCUC GGCUCCUC
3
GAGGAGCC CUGAUGAGGCCGUUAGGCCGAA AGAGGACU
9422


20
UCUCGGCUC CUCCCCGG
4
CCGGGGAG CUGAUGAGGCCGUUAGGCCGAA AGCCGAGA
9423


23
CGGCUCCUC CCCGGCAG
5
CUGCCGGG CUGAUGAGGCCGUUAGGCCGAA AGGAGCCG
9424


43
CGGCGGCUC GGAGCGGG
6
CCCGCUCC CUGAUGAGGCCGUUAGGCCGAA AGCCGCCG
9425


54
AGCGGGCUC CGGGGCUC
7
GAGCCCCG CUGAUGAGGCCGUUAGGCCGAA AGCCCGCU
9426


62
CCGGGGCUC GGGUGCAG
8
CUGCACCC CUGAUGAGGCCGUUAGGCCGAA AGCCCCGG
9427


97
GCGAGGAUU ACCCGGGG
9
CCCCGGGU CUGAUGAGGCCGUUAGGCCGAA AUCCUCGC
9429


98
CGAGGAUUA CCCGGGGA
10
UCCCCGGG CUGAUGAGGCCGUUAGGCCGAA AAUCCUCG
9429


113
GAAGUGCUU GUCUCCUG
11
CAGGAGAC CUGAUGAGGCCGUUAGGCCGAA ACCACUUC
9430


116
GUGGUUGUC UCCUGGCU
12
AGCCAGGA CUGAUGAGGCCGUUAGGCCGAA ACAACCAC
9431


118
GGUUGUCUC CUGGCUGG
13
CCAGCCAG CUGAUGAGGCCGUUAGGCCGAA AGACAACC
9432


145
CGCGCGCUC AGGGCGCG
14
CGCGCCCU CUGAUGAGGCCGUUAGGCCGAA AGCGCCCG
9433


185
GACGGACUC UGGCGGCC
15
GGCCGCCA CUGAUGAGGCCGUUAGGCCGAA AGUCCGUC
9434


198
GGCCGGGUC GUUGGCCG
16
CGGCCAAC CUGAUGAGGCCGUUAGGCCGAA ACCCGGCC
9435


201
CGGGUCGUU GGCCGGGG
17
CCCCGGCC CUGAUGAGGCCGUUAGGCCGAA ACGACCCG
9436


240
GGCCGCGUC GCGCUCAC
18
GUGAGCGC CUGAUGAGGCCGUUAGGCCGAA ACGCGGCC
9437


246
GUCGCGCUC ACCAUGGU
19
ACCAUGGU CUGAUGAGGCCGUUAGGCCGAA AGCGCGAC
9438


255
ACCAUGGUC AGCUACUG
20
CAGUAGCU CUGAUGAGGCCGUUAGGCCGAA ACCAUGGU
9439


260
GGUCAGCUA CUGGGACA
21
UGUCCCAG CUGAUGAGGCCGUUAGGCCGAA AGCUGACC
9440


276
ACCGGGGUC CUGCUGUG
22
CACAGCAG CUGAUGAGGCCGUUAGGCCGAA ACCCCGGU
9441


294
GCGCUGCUC AGCUGUCU
23
ACACAGCU CUGAUGAGGCCGUUAGGCCGAA AGCAGCGC
9442


301
UCAGCUGUC UGCUUCUC
24
GAGAAGCA CUGAUGAGGCCGUUAGGCCGAA ACAGCUGA
9443


306
UGUCUGCUU CUCACAGG
25
CCUGUGAG CUGAUGAGGCCGUUAGGCCGAA AGCAGACA
9444


307
GUCUGCUUC UCACAGGA
26
UCCUGUGA CUGAUGAGGCCGUUAGGCCGAA AAGCAGAC
9445


309
CUGCUUCUC ACAGGAUC
27
GAUCCUGU CUGAUGAGGCCGUUAGGCCGAA AGAAGCAG
9446


317
CACAGGAUC UAGUUCAG
28
CUGAACUA CUGAUGAGGCCGUUAGGCCGAA AUCCUGUG
9447


319
CAGGAUCUA GUUCAGGU
29
ACCUGAAC CUGAUGAGGCCGUUAGGCCGAA AGAUCCUG
9448


322
GAUCUAGUU CAGGUUCA
30
UGAACCUG CUGAUGAGGCCGUUAGGCCGAA ACUAGAUC
9449


323
AUCUAGUUC AGGUUCAA
31
UUGAACCU CUGAUGAGGCCGUUAGGCCGAA AACUAGAU
9450


328
GUUCAGGUU CAAAAUUA
32
UAAUUUUG CUGAUGAGGCCGUUAGGCCGAA ACCUGAAC
9451


329
UUCAGGUUC AAAAUUAA
33
UUAAUUUU CUGAUGAGGCCGUUAGGCCGAA AACCUGAA
9452


335
UUCAAAAUU AAAAGAUC
34
GAUCUUUU CUGAUGAGGCCGUUAGGCCGAA AUUUUGAA
9453


336
UCAAAAUUA AAAGAUCC
35
GGAUCUUU CUGAUGAGGCCGUUAGGCCGAA AAUUUUGA
9454


343
UAAAAGAUC CUGAACUG
36
CAGUUCAG CUGAUGAGGCCGUUAGGCCGAA AUCUUUUA
9455


355
AACUGAGUU UAAAAGGC
37
GCCUUUUA CUGAUGAGGCCGUUAGGCCGAA ACUCAGUU
9456


356
ACUGAGUUU AAAAGGCA
38
UGCCUUUU CUGAUGAGGCCGUUAGGCCGAA AACUCAGU
9457


357
CUGAGUUUA AAAGGCAC
39
GUGCCUUU CUGAUGAGGCCGUUAGGCCGAA AAACUCAG
9458


375
CAGCACAUC AUGCAAGC
40
GCUUGCAU CUGAUGAGGCCGUUAGGCCGAA AUGUGCUG
9459


400
CACUGCAUC UCCAAUGC
41
GCAUUGGA CUGAUGAGGCCGUUAGGCCGAA AUGCAGUG
9460


402
CUGCAUCUC CAAUGCAG
42
CUGCAUUG CUGAUGAGGCCGUUAGGCCGAA AGAUGCAG
9461


427
CAGCCCAUA AAUGGUCU
43
AGACCAUU CUGAUGAGGCCGUUAGGCCGAA AUGGGCUG
9462


434
UAAAUGGUC UUUGCCUG
44
CAGGCAAA CUGAUGAGGCCGUUAGGCCGAA ACCAUUUA
9463


436
AAUGGUCUU UGCCUGAA
45
UUCAGGCA CUGAUGAGGCCGUUAGGCCGAA AGACCAUU
9464


437
AUGGUCUUU GCCUGAAA
46
UUUCAGGC CUGAUGAGGCCGUUAGGCCGAA AAGACCAU
9465


454
UGGUGAGUA AGGAAAGC
47
GCUUUCCU CUGAUGAGGCCGUUAGGCCGAA ACUCACCA
9466


477
CUGAGCAUA ACUAAAUC
48
GAUUUAGU CUGAUGAGGCCGUUAGGCCGAA AUGCUCAG
9467


481
GCAUAACUA AAUCUGCC
49
GGCAGAUU CUGAUGAGGCCGUUAGGCCGAA AGUUAUGC
9468


485
AACUAAAUC UGCCUGUG
50
CACAGGCA CUGAUGAGGCCGUUAGGCCGAA AUUUAGUU
9469


512
CAAACAAUU CUGCAGUA
51
UACUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUGUUUG
9470


513
AAACAAUUC UGCAGUAC
52
GUACUGCA CUGAUGAGGCCGUUAGGCCGAA AAUUGUUU
9471


520
UCUGCAGUA CUUUAACC
53
GGUUAAAG CUGAUGAGGCCGUUAGGCCGAA ACUGCAGA
9472


523
GCAGUACUU UAACCUUG
54
CAAGGUUA CUGAUGAGGCCGUUAGGCCGAA AGUACUGC
9473


524
CAGUACUUU AACCUUGA
55
UCAAGGUU CUGAUGAGGCCGUUAGGCCGAA AAGUACUG
9474


525
AGUACUUUA ACCUUGAA
56
UUCAAGGU CUGAUGAGGCCGUUAGGCCGAA AAAGUACU
9475


530
UUUAACCUU GAACACAG
57
CUGUGUUC CUGAUGAGGCCGUUAGGCCGAA AGGUUAAA
9476


541
ACACAGCUC AAGCAAAC
58
GUUUGCUU CUGAUGAGGCCGUUAGGCCGAA AGCUGUCU
9477


560
CACUGGCUU CUACAGCU
59
AGCUGUAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGUG
9478


561
ACUGGCUUC UACAGCUG
60
CAGCUGUA CUGAUGAGGCCGUUAGGCCGAA AAGCCAGU
9479


563
UGGCUUCUA CAGCUGCA
61
UGCAGCUO CUGAUGAGGCCGUUAGGCCGAA AGAAGCCA
9480


575
CUGCAAAUA UCUAGCUG
62
CAGGUAGA CUGAUGAGGCCGUUAGGCCGAA AUUUGCAG
9481


577
GCAAAUAUC UAGCUGUA
63
UACAGCUA CUGAUGAGGCCGUUAGGCCGAA AUAUUUGC
9482


579
AAAUAUCUA GCUGUACC
64
GGUACAGC CUGAUGAGGCCGUUAGGCCGAA AGAUAUUU
9483


585
CUAGCUGUA CCUACUUC
65
GAAGUAGG CUGAUGAGGCCGUUAGGCCGAA ACAGCUAG
9484


589
CUGUACCUA CUUCAAAG
66
CUUUGAAG CUGAUGAGGCCGUUAGGCCGAA AGGUACAG
9485


592
UACCUACUU CAAAGAAG
67
CUUCUUUG CUGAUGAGGCCGUUAGGCCGAA AGUAGGUA
9486


593
ACCUACUUC AAAGAAGA
68
UCUUCUUU CUGAUGAGGCCGUUAGGCCGAA AAGUAGGU
9487


614
AACAGAAUC UGCAAUCU
69
AGAUUGCA CUGAUGAGGCCGUUAGGCCGAA AUUCUGUU
9488


621
UCUGCAAUC UAUAUAUU
70
AAUAUAUA CUGAUGAGGCCGUUAGGCCGAA AUUGCAGA
9489


623
UGCAAUCUA UAUAUUUA
71
UAAAUAUA CUGAUGAGGCCGUUAGGCCGAA AGAUUGCA
9490


625
CAAUCUAUA UAUUUAUU
72
AAUAAAUA CUGAUGAGGCCGUUAGGCCGAA AUAGAUUG
9491


627
AUCUAUAUA UUUAUUAG
73
CUAAUAAA CUGAUGAGGCCGUUAGGCCGAA AUAUAGAU
9492


629
CUAUAUAUU UAUUAGUG
74
CACUAAUA CUGAUGAGGCCGUUAGGCCGAA AUAUAUAG
9493


630
UAUAUAUUU AUUAGUGA
75
UCACUAAU CUGAUGAGGCCGUUAGGCCGAA AAUAUAUA
9494


631
AUAUAUUUA UUAGUGAU
76
AUCACUAA CUGAUGAGGCCGUUAGGCCGAA AAAUAUAU
9495


633
AUAUUUAUU AGUGAUAC
77
GUAUCACU CUGAUGAGGCCGUUAGGCCGAA AUAAAUAU
9496


634
UAUUUAUUA GUGAUACA
78
UGUAUCAC CUGAUGAGGCCGUUAGGCCGAA AAUAAAUA
9497


640
UUAGUGAUA CAGGUAGA
79
UCUACCUG CUGAUGAGGCCGUUAGGCCGAA AUCACUAA
9498


646
AUACAGGUA GACCUUUC
80
GAAAGGUC CUGAUGAGGCCGUUAGGCCGAA ACCUGUAU
9499


652
GUAGACCUU UCGUAGAG
81
CUCUACGA CUGAUGAGGCCGUUAGGCCGAA AGGUCUAC
9500


653
UAGACCUUU CGUAGAGA
82
UCUCUACG CUGAUGAGGCCGUUAGGCCGAA AAGGUCUA
9501


654
AGACCUUUC GUAGAGAU
83
AUCUCUAC CUGAUGAGGCCGUUAGGCCGAA AAAGGUCU
9502


657
CCUUUCGUA GAGAUGUA
84
UACAUCUC CUGAUGAGGCCGUUAGGCCGAA ACGAAAGG
9503


665
AGAGAUGUA CAGUGAAA
85
UUUCACUG CUGAUGAGGCCGUUAGGCCGAA ACAUCUCU
9504


675
AGUGAAAUC CCCGAAAU
86
AUUUCGGG CUGAUGAGGCCGUUAGGCCGAA AUUUCACU
9505


684
CCCGAAAUU AUACACAU
87
AUGUGUAU CUGAUGAGGCCGUUAGGCCGAA AUUUCGGG
9506


685
CCGAAAUUA UACACAUG
88
CAUGUGUA CUGAUGAGGCCGUUAGGCCGAA AAUUUCGG
9507


687
GAAAUUAUA CACAUGAC
89
GUCAUGUG CUGAUGAGGCCGUUAGGCCGAA AUAAUUUC
9508


711
AGGGAGCUC GUCAUUCC
90
GGAAUGAC CUGAUGAGGCCGUUAGGCCGAA AGCUCCCU
9509


714
GAGCUCGUC AUUCCCUG
91
CAGGGAAU CUGAUGAGGCCGUUAGGCCGAA ACGAGCUC
9510


717
CUCGUCAUU CCCUGCCG
92
CGGCAGGG CUGAUGAGGCCGUUAGGCCGAA AUGACGAG
9511


718
UCGUCAUUC CCUGCCGG
93
CCGGCAGG CUGAUGAGGCCGUUAGGCCGAA AAUGACGA
9512


729
UGCCGGGUU ACGUCACC
94
GGUGACGU CUGAUGAGGCCGUUAGGCCGAA ACCCGGCA
9513


730
GCCGGGUUA CGUCACCU
95
AGGUGACG CUGAUGAGGCCGUUAGGCCGAA AACCCGGC
9514


734
GGUUACGUC ACCUAACA
96
UGUUAGGU CUGAUGAGGCCGUUAGGCCGAA ACGUAACC
9515


739
CGUCACCUA ACAUCACU
97
AGUGAUGU CUGAUGAGGCCGUUAGGCCGAA AGGUGACG
9516


744
CCUAACAUC ACUGUUAC
98
GUAACAGU CUGAUGAGGCCGUUAGGCCGAA AUGUUAGG
9517


750
AUCACUGUU ACUUUAAA
99
UUUAAAGU CUGAUGAGGCCGUUAGGCCGAA ACAGUGAU
9518


751
UCACUGUUA CUUUAAAA
100
UUUUAAAG CUGAUGAGGCCGUUAGGCCGAA AACAGUGA
9519


754
CUGUUACUU UAAAAAAG
101
CUUUUUUA CUGAUGAGGCCGUUAGGCCGAA AGUAACAG
9520


755
UGUUACUUU AAAAAAGU
102
ACUUUUUU CUGAUGAGGCCGUUAGGCCGAA AAGUAACA
9521


756
GUUACUUUA AAAAAGUU
103
AACUUUUU CUGAUGAGGCCGUUAGGCCGAA AAAGUAAC
9522


764
AAAAAAGUU UCCACUUG
104
CAAGUGGA CUGAUGAGGCCGUUAGGCCGAA ACUUUUUU
9523


765
AAAAAGUUU CCACUUGA
105
UCAAGUGG CUGAUGAGGCCGUUAGGCCGAA AACUUUUU
9524


766
AAAAGUUUC CACUUGAC
106
GUCAAGUG CUGAUGAGGCCGUUAGGCCGAA AAACUUUU
9525


771
UUUCCACUU GACACUUU
107
AAAGUGUC CUGAUGAGGCCGUUAGGCCGAA AGUGGAAA
9526


778
UUGACACUU UGAUCCCU
108
AGGGAUCA CUGAUGAGGCCGUUAGGCCGAA AGUGUCAA
9527


779
UGACACUUU GAUCCCUG
109
CAGGGAUC CUGAUGAGGCCGUUAGGCCGAA AAGUGUCA
9528


783
ACUUUGAUC CCUGAUGG
110
CCAUCAGG CUGAUGAGGCCGUUAGGCCGAA AUCAAAGU
9529


801
AAACGCAUA AUCUGGGA
111
UCCCAGAU CUGAUGAGGCCGUUAGGCCGAA AUGCGUUU
9530


804
CGCAUAAUC UGGGACAG
112
CUGUCCCA CUGAUGAGGCCGUUAGGCCGAA AUUAUGCG
9531


814
GGGACAGUA GAAAGGGC
113
GCCCUUUC CUGAUGAGGCCGUUAGGCCGAA ACUGUCCC
9532


824
AAAGGGCUU CAUCAUAU
114
AUAUGAUG CUGAUGAGGCCGUUAGGCCGAA AGCCCUUU
9533


825
AAGGGCUUC AUCAUAUC
115
GAUAUGAU CUGAUGACGCCGUUAGGCCGAA AAGCCCUU
9534


828
GGCUUCAUC AUAUCAAA
116
UUUGAUAU CUGAUGAGGCCGUUAGGCCGAA AUGAAGCC
9535


831
UUCAUCAUA UCAAAUGC
117
GCAUUUGA CUGAUGAGGCCGUUAGGCCGAA AUGAUGAA
9536


833
CAUCAUAUC AAAUGCAA
118
UUGCAUUU CUGAUGAGGCCGUUAGGCCGAA AUAUGAUG
9537


845
UGCAACGUA CAAAGAAA
119
UUUCUUUG CUGAUGAGGCCGUUAGGCCGAA ACGUUGCA
9538


855
AAAGAAAUA GGGCUUCU
120
ACAAGCCC CUGAUGAGGCCGUUAGGCCGAA AUUUCUUU
9539


861
AUAGGGCUU CUGACCUG
121
CAGGUCAG CUGAUGAGGCCGUUAGGCCGAA AGCCCUAU
9540


862
UAGGGCUUC UGACCUGU
122
ACAGGUCA CUGAUGAGGCCGUUAGGCCGAA AAGCCCUA
9541


882
GCAACAGUC AAUGGGCA
123
UGCCCAUU CUGAUGAGGCCGUUAGGCCGAA ACUGUUGC
9542


892
AUGGGCAUU UGUAUAAG
124
CUUAUACA CUGAUGAGGCCGUUAGGCCGAA AUGCCCAU
9543


893
UGGGCAUUU GUAUAAGA
125
UCUUAUAC CUGAUGAGGCCGUUAGGCCGAA AAUGCCCA
9544


896
GCAUUUGUA UAAGACAA
126
UUGUCUUA CUCAUGAGGCCGUUAGGCCGAA ACAAAUGC
9545


898
AUUUGUAUA AGACAAAC
127
GUUUGUCU CUGAUGAGGCCGUUAGGCCGAA AUACAAAU
9546


908
GACAAACUA UCUCACAC
128
GUGUGAGA CUGAUGAGGCCGUUAGGCCGAA AGUUUGUC
9547


910
CAAACUAUC UCACACAU
129
AUGUGUGA CUGAUGAGGCCGUUAGGCCGAA AUAGUUUG
9548


912
AACUAUCUC ACACAUCG
130
CGAUGUGU CUGAUGAGGCCGUUAGGCCGAA AGAUAGUU
9549


919
UCACACAUC GACAAACC
131
GGUUUGUC CUGAUGAGGCCGUUAGGCCGAA AUGUGUGA
9550


931
AAACCAAUA CAAUCAUA
132
UAUGAUUG CUGAUGAGGCCGUUAGGCCGAA AUUGGUUU
9551


936
AAUACAAUC AUAGAUGU
133
ACAUCUAU CUGAUGAGGCCGUUAGGCCGAA AUUGUAUU
9552


939
ACAAUCAUA GAUGUCCA
134
UGGACAUC CUGAUGAGGCCGUUAGGCCGAA AUGAUUGU
9553


945
AUAGAUGUC CAAAUAAG
135
CUUAUUUG CUGAUGAGGCCGUUAGGCCGAA ACAUCUAG
9554


951
GUCCAAAUA AGCACACC
136
GGUGUGCU CUGAUGAGGCCGUUAGGCCGAA AUCUGGAC
9555


969
CGCCCAGUC AAAUUACU
137
AGUAAUUU CUGAUGAGGCCGUUAGGCCGAA ACUGGGCG
9556


974
AGUCAAAUU ACUUAGAG
138
CUCUAAGU CUGAUGAGGCCGUUAGGCCGAA AUUUGACU
9557


975
GUCAAAUUA CUUAGAGG
139
CCUCUAAG CUGAUGAGGCCGUUAGGCCGAA AAUVUGAC
9558


978
AAAUUACUU AGAGOCCA
140
UGGCCUCU CUGAUGAGGCCGUUAGGCCGAA AGUAAUUU
9559


979
AAUUACUUA GAGGCCAU
141
AUGGCCUC CUGAUGAGGCCGUUAGGCCGAA AAGUAAUU
9560


988
GAGGCCAUA CUCUUGUC
142
GACAAGAG CUGAUGAGGCCGUUAGGCCGAA AUGGCCUC
9561


991
GCCAUACUC UUGUCCUC
143
GAGGACAA CUGAUGAGGCCGUUAGGCCGAA AGUAUGGC
9562


993
CAUACUCUU GUCCUCAA
144
UUGAGGAC CUGAUGAGGCCGUUAGGCCGAA AGAGUAUG
9563


996
ACUCUUGUC CUCAAUUG
145
CAAUUGAG CUGAUGAGGCCGUUAGGCCGAA ACAAGAGU
9564


999
CUUGUCCUC AAUUGUAC
146
GUACAAUU CUGAUGAGGCCGUUAGGCCGAA AGGACAAG
9565


1003
UCCUCAAUU GUACUGCU
147
AGCAGUAC CUGAUGAGGCCGUUAGGCCGAA AUUGAGGA
9566


1006
UCAAUUGUA CUGCUACC
148
GGUAGCAG CUGAUGAGGCCGUUAGGCCGAA ACAAUUGA
9567


1012
GUACUGCUA CCACUCCC
149
GGGACUGG CUGAUGAGGCCGUUAGGCCGAA AGCAGUAC
9568


1018
CUACCACUC CCUUGAAC
150
GUUCAAGG CUGAUGAGGCCGUUAGGCCGAA AGUGGUAG
9569


1022
CACUCCCUU GAACACGA
151
UCGUGUUC CUGAUGAGGCCGUUAGGCCGAA AGGGAGUG
9570


1035
ACGAGAGUU CAAAUGAC
152
GUCAUUUG CUGAUGAGGCCGUUAGGCCGAA ACUCUCGU
9571


1036
CGAGAGUUC AAAUGACC
153
GGUCAUUU CUGAUGAGGCCGUUAGGCCGAA AACUCUCG
9572


1051
CCUGGAGUU ACCCUGAU
154
AUCAGGGU CUGAUGAGGCCGUUAGGCCGAA ACUCCAGG
9573


1052
CUGGAGUUA CCCUGAUG
155
CAUCAGUG CUGAUGAGGCCGUUAGGCCGAA AACUCCAG
9574


1069
AAAAAAAUA AGAGAGCU
156
AGCUCUCU CUGAUGAGGCCGUUAGGCCGAA AUUUUUUU
9575


1078
AGAGAGCUU CCGUAAGG
157
CCUUACGG CUGAUGAGGCCGUUAGGCCGAA AGCUCUCU
9576


1079
GAGAGCUUC CGUAAGGC
158
GCCUUACG CUGAUGAGGCCGUUAGGCCGAA AAGCUCUC
9577


1083
GCUUCCGUA AGGCGACG
159
CGUCGCCU CUGAUGAGGCCGUUAGGCCGAA ACGGAAGC
9578


1095
CGACGAAUU GACCAAAG
160
CUUUGGUC CUGAUGAGGCCGUUAGGCCGAA AUUCGUCG
9579


1108
AAAGCAAUU CCCAUGCC
161
GGCAUGGG CUGAUGAGGCCGUUAGGCCGAA AUUGCUUU
9580


1109
AAGCAAUUC CCAUGCCA
162
UGGCAUGG CUGAUGAGGCCGUUAGGCCGAA AAUUGCUU
9581


1122
GCCAACAUA UUCUACAG
163
CUGUAGAA CUGAUGAGGCCGUUAGGCCGAA AUGUUGGC
9582


1124
CAACAUAUU CUACAGUG
164
CACUGUAG CUGAUGAGGCCGUUAGGCCGAA AUAUGUUG
9583


1125
AACAUAUUC UACAGUGU
165
ACACUGUA CUGAUGAGGCCGUUAGGCCGAA AAUAUGUU
9584


1127
CAUAUUCUA CAGUGUUC
166
GAACACUG CUGAUGAGGCCGUUAGGCCGAA AGAAUAUG
9585


1134
UACAGUGUU CUUACUAU
167
AUAGUAAG CUGAUGAGGCCGUUAGGCCGAA ACACUGUA
9586


1135
ACAGUGUUC UUACUAUU
168
AAUAGUAA CUGAUGAGGCCGUUAGGCCGAA AACACUGU
9587


1137
AGUGUUCUU ACUAUUGA
169
UCAAUAGU CUGAUGAGGCCGUUAGGCCGAA AGAACACU
9588


1138
GUGUUCUUA CUAUUGAC
170
GUCAAUAG CUGAUGAGGCCGUUAGGCCGAA AAGAACAC
9589


1141
UUCUUACUA UUGACAAA
171
UUUGUCAA CUGAUGAGGCCGUUAGGCCGAA AGUAAGAA
9590


1143
CUUACUAUU GACAAAAU
172
AUUUUGUC CUGAUGAGGCCGUUAGGCCGAA AUAGUAAG
9591


1173
AAAGGACUU UAUACUUG
173
CAAGUAUA CUGAUGAGGCCGUUAGGCCGAA AGUCCUUU
9592


1174
AAGGACUUU AUACUUGU
174
ACAAGUAU CUGAUGAGGCCGUUAGGCCGAA AAGUCCUU
9593


1175
AGGACUUUA UACUUGUC
175
GACAAGUA CUGAUGAGGCCGUUAGGCCGAA AAAGUCCU
9594


1177
GACUUUAUA CUUGUCGU
176
ACGACAAG CUGAUGAGGCCGUUAGGCCGAA AUAAAGUC
9595


1180
UUUAUACUU GUCGUGUA
177
UACACGAC CUGAUGAGGCCGUUAGGCCGAA AGUAUAAA
9596


1183
AUACUUGUC GUGUAAGG
178
CCUUACAC CUGAUGAGGCCGUUAGGCCGAA ACAAGUAU
9597


1188
UGUCGUGUA AGGAGUGG
179
CCACUCCU CUGAUGAGGCCGUUAGGCCGAA ACACGACA
9598


1202
UGGACCAUC AUUCAAAU
180
AUUUGAAU CUGAUGAGGCCGUUAGGCCGAA AUGGUCCA
9599


1205
ACCAUCAUU CAAAUCUG
181
CAGAUUUG CUGAUGAGGCCGUUAGGCCGAA AUGAUGGU
9600


1206
CCAUCAUUC AAAUCUGU
182
ACAGAUUU CUGAUGAGGCCGUUAGGCCGAA AAUGAUGG
9601


1211
AUUCAAAUC UGUUAACA
183
UGUUAACA CUGAUGAGGCCGUUAGGCCGAA AUUUGAAU
9602


1215
AAAUCUGUU AACACCUC
184
GAGGUGUU CUGAUGAGGCCGUUAGGCCGAA ACAGAUUU
9603


1216
AAUCUGUUA ACACCUCA
185
UGAGGUGU CUGAUGAGGCCGUUAGGCCGAA AACAGAUU
9604


1223
UAACACCUC AGUGCAUA
186
UAUGCACU CUGAUGAGGCCGUUAGGCCGAA AGGUGUUA
9605


1231
CAGUGCAUA UAUAUGAU
187
AUCAUAUA CUGAUGAGGCCGUUAGGCCGAA AUGCACUG
9606


1233
GUGCAUAUA UAUGAUAA
188
UUAUCAUA CUGAUGAGGCCGUUAGGCCGAA AUAUGCAC
9607


1235
GCAUAUAUA UGAUAAAG
189
CUUUAUCA CUGAUGAGGCCGUUAGGCCGAA AUAUAUGC
9608


1240
UAUAUGAUA AAGCAUUC
190
GAAUGCUU CUGAUGAGGCCGUUAGGCCGAA AUCAUAUA
9609


1247
UAAAGCAUU CAUCACUG
191
CAGUGAUG CUGAUGAGGCCGUUAGGCCGAA AUGCUUUA
9610


1248
AAAGCAUUC AUCACUGU
192
ACAGUGAU CUGAUGAGGCCGUUAGGCCGAA AAUGCUUU
9611


1251
GCAUUCAUC ACUGUGAA
193
UUCACAGU CUGAUGAGGCCGUUAGGCCGAA AUGAAUGC
9612


1264
UGAAACAUC GAAAACAG
194
CUGUUUUC CUGAUGAGGCCGUUAGGCCGAA AUGUUUCA
9613


1281
CAGGUGCUU GAAACCGU
195
ACGGUUUC CUGAUGAGGCCGUUAGGCCGAA AGCACCUG
9614


1290
GAAACCGUA GCUGGCAA
196
UUGCCAGC CUGAUGAGGCCGUUAGGCCGAA ACGGUUUC
9615


1304
CAAGCGGUC UUACCGGC
197
GCCGGUAA CUGAUGAGGCCGUUAGGCCGAA ACCGCUUG
9616


1306
AGCGGUCUU ACCGGCUC
198
GAGCCGGU CUGAUGAGGCCGUUAGGCCGAA AGACCGCU
9617


1307
GCGGUCUUA CCGGCUCU
199
AGAGCCGG CUGAUGAGGCCGUUAGGCCGAA AAGACCGC
9618


1314
UACCGGCUC UCUAUGAA
200
UUCAUAGA CUGAUGAGGCCGUUAGGCCGAA AGCCGGUA
9619


1316
CCGGCUCUC UAUGAAAG
201
CUUUCAUA CUGAUGAGGCCGUUAGGCCGAA AGAGCCGG
9620


1318
GGCUCUCUA UGAAAGUG
202
CACUUUCA CUGAUGAGGCCGUUAGGCCGAA AGAGAGCC
9621


1334
GAAGGCAUU UCCCUCGC
203
GCGAGGGA CUGAUGAGGCCGUUAGGCCGAA AUGCCUUC
9622


1335
AAGGCAUUU CCCUCGCC
204
GGCGAGGG CUGAUGAGGCCGUUAGGCCGAA AAUGCCUU
9623


1336
AGGCAUUUC CCUCGCCG
205
CGGCGAGG CUGAUGAGGCCGUUAGGCCGAA AAAUGCCU
9624


1340
AUUUCCCUC GCCGGAAG
206
CUUCCGGC CUGAUGAGGCCGUUAGGCCGAA AGGGAAAU
9625


1350
CCGGAAGUU GUAUGGUU
207
AACCAUAC CUGAUGAGGCCGUUAGGCCGAA ACUUCCGG
9626


1353
GAAGUUGUA UGGUUAAA
208
UUUAACCA CUGAUGAGGCCGUUAGGCCGAA ACAACUUC
9627


1358
UGUAUGGUU AAAAGAUG
209
CAUCUUUU CUGAUGAGGCCGUUAGGCCGAA ACCAUACA
9628


1359
GUAUGGUUA AAAGAUGG
210
CCAUCUUU CUGAUGAGGCCGUUAGGCCGAA AACCAUAC
9629


1370
AGAUGGGUU ACCUGCGA
211
UCGCAGGU CUGAUGAGGCCGUUAGGCCGAA ACCCAUCU
9630


1371
GAUGGGUUA CCUGCGAC
212
GUCGCAGG CUGAUGAGGCCGUUAGGCCGAA AACCCAUC
9631


1388
UGAGAAAUC UGCUCGCU
213
AGCGAGCA CUGAUGAGGCCGUUAGGCCGAA AUUUCUCA
9632


1393
AAUCUGCUC GCUAUUUG
214
CAAAUAGC CUGAUGAGGCCGUUAGGCCGAA AGCAGAUU
9633


1397
UGCUCGCUA UUUGACUC
215
GAGUCAAA CUGAUGAGGCCGUUAGGCCGAA AGCGAGCA
9634


1399
CUCGCUAUU UGACUCGU
216
ACGAGUCA CUGAUGAGGCCGUUAGGCCGAA AUAGCGAG
9635


1400
UCGCUAUUU GACUCGUG
217
CACGAGUC CUGAUGAGGCCGUUAGGCCGAA AAUAGCGA
9636


1405
AUUUGACUC GUGGCUAC
218
GUAGCCAC CUGAUGAGGCCGUUAGGCCGAA AGUCAAAU
9637


1412
UCGUGGCUA CUCGUUAA
219
UUAACGAG CUGAUGAGGCCGUUAGGCCGAA AGCCACGA
9638


1415
UGGCUACUC GUUAAUUA
220
UAAUUAAC CUGAUGAGGCCGUUAGGCCGAA AGUAGCCA
9639


1418
CUACUCGUU AAUUAUCA
221
UGAUAAUU CUGAUGAGGCCGUUAGGCCGAA ACGAGUAG
9640


1419
UACUCGUUA AUUAUCAA
222
UUGAUAAU CUGAUGAGGCCGUUAGGCCGAA AACGAGUA
9641


1422
UCGUUAAUU AUCAAGGA
223
UCCUUGAU CUGAUGAGGCCGUUAGGCCGAA AUUAACGA
9642


1423
CGUUAAUUA UCAAGGAC
224
GUCCUUGA CUGAUGAGGCCGUUAGGCCGAA AAUUAACG
9643


1425
UUAAUUAUC AAGGACGU
225
ACGUCCUU CUGAUGAGGCCGUUAGGCCGAA AUAAUUAA
9644


1434
AAGGACGUA ACUGAAGA
226
UCUUCAGU CUGAUGAGGCCGUUAGGCCGAA ACGUCCUU
9645


1456
CAGGGAAUU AUACAAUC
227
GAUUGUAU CUGAUGAGGCCGUUAGGCCGAA AUUCCCUG
9646


1457
AGGGAAUUA UACAAUCU
228
AGAUUGUA CUGAUGAGGCCGUUAGGCCGAA AAUUCCCU
9647


1459
GGAAUUAUA CAAUCUUG
229
CAAGAUUG CUGAUGAGGCCGUUAGGCCGAA AUAAUUCC
9648


1464
UAUACAAUC UUCCUGAG
230
CUCAGCAA CUGAUGAGGCCGUUAGGCCGAA AUUGUAUA
9649


1466
UACAAUCUU GCUGAGCA
231
UGCUCAGC CUGAUGAGGCCGUUAGGCCGAA AGAUUGUA
9650


1476
CUGAGCAUA AAACAGUC
232
GACUGUUU CUGAUGAGGCCGUUAGGCCGAA AUGCUCAG
9651


1484
AAAACAGUC AAAUGUGU
233
ACACAUUU CUGAUGAGGCCGUUAGGCCGAA ACUGUUUU
9652


1493
AAAUGUGUU UAAAAACC
234
GGUUUUUA CUGAUGAGGCCGUUAGGCCGAA ACACAUUU
9653


1494
AAUGUGUUU AAAAACCU
235
AGGUUUUU CUGAUGAGGCCGUUAGGCCGAA AACACAUU
9654


1495
AUGUGUUUA AAAACCUC
236
GAGGUUUU CUGAUGAGGCCGUUAGGCCGAA AAACACAU
9655


1503
AAAAACCUC ACUGCCAC
237
GUGGCAGU CUGAUGAGGCCGUUAGGCCGAA AGGUUUUU
9656


1513
CUGCCACUC UAAUUGUC
238
GACAAUUA CUGAUGAGGCCGUUAGGCCGAA AGUGGCAG
9657


1515
GCCACUCUA AUUGUCAA
239
UUGACAAU CUGAUGAGGCCGUUAGGCCGAA AGAGUGGC
9658


1518
ACUCUAAUU GUCAAUGU
240
ACAUUGAC CUGAUGAGGCCGUUAGGCCGAA AUUAGAGU
9659


1521
CUAAUUGUC AAUGUGAA
241
UUCACAUU CUGAUGAGGCCGUUAGGCCGAA ACAAUUAG
9660


1539
CCCCAGAUU UACGAAAA
242
UUUUCGUA CUGAUGAGGCCGUUAGGCCGAA AUCUGGGG
9661


1540
CCCAGAUUU ACGAAAAG
243
CUUUUCGU CUGAUGAGGCCGUUAGGCCGAA AAUCUGGG
9662


1541
CCAGAUUUA CGAAAAGG
244
CCUUUUCG CUGAUGAGGCCGUUAGGCCGAA AAAUCUGG
9663


1556
GGCCGUGUC AUCGUUUC
245
GAAACGAU CUGAUGAGGCCGUUAGGCCGAA ACACGGCC
9664


1559
CGUGUCAUC GUUUCCAG
246
CUGGAAAC CUGAUGAGGCCGUUAGGCCGAA AUGACACG
9665


1562
GUCAUCGUU UCCAGACC
247
GGUCUGGA CUGAUGAGGCCGUUAGGCCGAA ACGAUGAC
9666


1563
UCAUCGUUU CCAGACCC
248
GGGUCUGG CUGAUGAGGCCGUUAGGCCGAA AACGAUGA
9667


1564
CAUCGUUUC CAGACCCG
249
CGGGUCUG CUGAUGAGGCCGUUAGGCCGAA AAACGAUG
9668


1576
ACCCGGCUC UCUACCCA
250
UGGGUAGA CUGAUGAGGCCGUUAGGCCGAA AGCCGGGU
9669


1578
CCGGCUCUC UACCCACU
251
AGUGGGUA CUGAUGAGGCCGUUAGGCCGAA AGAGCCGG
9670


1580
GGCUCUCUA CCCACUGG
252
CCAGUGGG CUGAUGAGGCCGUUAGGCCGAA AGAGAGCC
9671


1602
AGACAAAUC CUCACUUG
253
CAAGUCAG CUGAUGAGGCCGUUAGGCCGAA AUUUGUCU
9672


1609
UCCUGACUU GUACCGCA
254
UGCGGUAC CUGAUGAGGCCGUUAGGCCGAA AGUCAGGA
9673


1612
UGACUUGUA CCGCAUAU
255
AUAUGCGG CUGAUGAGGCCGUUAGGCCGAA ACAAGUCA
9674


1619
UACCGCAUA UGGUAUCC
256
GGAUACCA CUGAUGAGGCCGUUAGGCCGAA AUGCGGUA
9675


1624
CAUAUGGUA UCCCUCAA
257
UUGAGGGA CUGAUGAGGCCGUUAGGCCGAA ACCAUAUG
9676


1626
UAUGGUAUC CCUCAACC
258
GGUUGAGG CUGAUGAGGCCGUUAGGCCGAA AUACCAUA
9677


1630
GUAUCCCUC AACCUACA
259
UGUAGGUU CUGAUGAGGCCGUUAGGCCGAA AGGGAUAC
9678


1636
CUCAACCUA CAAUCAAG
260
CUUGAUUG CUGAUGAGGCCGUUAGGCCGAA AGGUUGAG
9679


1641
CCUACAAUC AAGUGGUU
261
AACCACUU CUGAUGAGGCCGUUAGGCCGAA AUUGUAGG
9680


1649
CAAGUGGUU CUGGCACC
262
GGUGCCAG CUGAUGAGGCCGUUAGGCCGAA ACCACUUG
9681


1650
AAGUGGUUC UGGCACCC
263
GGGUGCCA CUGAUGAGGCCGUUAGGCCGAA AACCACUU
9682


1663
ACCCCUGUA ACCAUAAU
264
AUUAUGGU CUGAUGAGGCCGUUAGGCCGAA ACAGGCGU
9683


1669
GUAACCAUA AUCAUUCC
265
GGAAUGAU CUGAUGAGGCCGUUAGGCCGAA AUGGUUAC
9684


1672
ACCAUAAUC AUUCCGAA
266
UUCGGAAU CUGAUGAGGCCGUUAGGCCGAA AUUAUGGU
9685


1675
AUAAUCAUU CCGAAGCA
267
UGCUUCGG CUGAUGAGGCCGUUAGGCCGAA AUGAUUAU
9686


1676
UAAUCAUUC CGAAGCAA
268
UUGCUUCG CUGAUGAGGCCGUUAGGCCGAA AAUGAUUA
9687


1694
GUGUGACUU UUGUUCCA
269
UGGAACAA CUGAUGAGGCCGUUAGGCCGAA AGUCACAC
9688


1695
UGUGACUUU UGUUCCAA
270
UUGGAACA CUGAUGAGGCCGUUAGGCCGAA AAGUCACA
9689


1696
GUGACUUUU GUUCCAAU
271
AUUGGAAC CUGAUGAGGCCGUUAGGCCGAA AAAGUCAC
9690


1699
ACUUUUGUU CCAAUAAU
272
AUUAUUGG CUGAUGAGGCCGUUAGGCCGAA ACAAAAGU
9691


1700
CUUUUGUUC CAAUAAUG
273
CAUUAUUG CUGAUGAGGCCGUUAGGCCGAA AACAAAAG
9692


1705
GUUCCAAUA AUGAAGAG
274
CUCUUCAU CUGAUGAGGCCGUUAGGCCGAA AUUGGAAC
9693


1715
UGAAGAGUC CUUUAUCC
275
GGAUAAAG CUGAUGAGGCCGUUAGGCCGAA ACUCUUCA
9694


1718
AGAGUCCUU UAUCCUGG
276
CCAGGAUA CUGAUGAGGCCGUUAGGCCGAA AGGACUCU
9695


1719
GAGUCCUUU AUCCUGGA
277
UCCAGGAU CUGAUGAGGCCGUUAGGCCGAA AAGGACUC
9696


1720
AGUCCUUUA UCCUGGAU
278
AUCCAGGA CUGAUGAGGCCGUUAGGCCGAA AAAGGACU
9697


1722
UCCUUUAUC CUGGAUGC
279
GCAUCCAG CUGAUGAGGCCGUUAGGCCGAA AUAAAGGA
9698


1755
AACAGAAUU GAGAGCAU
280
AUGCUCUC CUGAUGAGGCCGUUAGGCCGAA AUUCUGUU
9699


1764
GAGAGCAUC ACUCAGCG
281
CGCUGAGU CUGAUGAGGCCGUUAGGCCGAA AUGCUCUC
9700


1768
GCAUCACUC AGCGCAUG
282
CAUGCGCU CUGAUGAGGCCGUUAGGCCGAA AGUGAUGC
9701


1782
AUGGCAAUA AUAGAAGG
283
CCUUCUAU CUGAUGAGGCCGUUAGGCCGAA AUUGCCAU
9702


1785
GCAAUAAUA GAAGGAAA
284
UUUCCUUC CUGAUGAGGCCGUUAGGCCGAA AUUAUUGC
9703


1798
GAAAGAAUA AGAUGGCU
285
AGCCAUCU CUGAUGAGGCCGUUAGGCCGAA AUUCUUUC
9704


1807
AGAUGGCUA GCACCUUG
286
CAAGGUGC CUGAUGAGGCCGUUAGGCCGAA AGCCAUCU
9705


1814
UAGCACCUU GGUUGUGG
287
CCACAACC CUGAUGAGGCCGUUAGGCCGAA AGGUGCUA
9706


1818
ACCUUGGUU GUGGCUGA
288
UCAGCCAC CUGAUGAGGCCGUUAGGCCGAA ACCAAGGU
9707


1829
GGCUGACUC UAGAAUUU
289
AAAUUCUA CUGAUGAGGCCGUUAGGCCGAA AGUCAGCC
9708


1831
CUGACUCUA GAAUUUCU
290
AGAAAUUC CUGAUGAGGCCGUUAGGCCGAA AGAGUCAG
9709


1836
UCUAGAAUU UCUGGAAU
291
AUUCCAGA CUGAUGAGGCCGUUAGGCCGAA AGUCUAGA
9710


1837
CUAGAAUUU CUGGAAUC
292
GAUUCCAG CUGAUGAGGCCGUUAGGCCGAA AAUUCUAG
9711


1838
UAGAAUUUC UGGAAUCU
293
AGAUUCCA CUGAUGAGGCCGUUAGGCCGAA AAAUUCUA
9712


1845
UCUGGAAUC UACAUUUG
294
CAAAUGUA CUGAUGAGGCCGUUAGGCCGAA AUUCCAGA
9713


1847
UGGAAUCUA CAUUUGCA
295
UGCAAAUG CUGAUGAGGCCGUUAGGCCGAA AGAUUCCA
9714


1851
AUCUACAUU UGCAUAGC
296
GCUAUGCA CUGAUGAGGCCGUUAGGCCGAA AUGUAGAU
9715


1852
UCUACAUUU GCAUAGCU
297
AGCUAUGC CUGAUGAGGCCGUUAGGCCGAA AAUGUAGA
9716


1857
AUUUGCAUA GCUUCCAA
298
UUGGAAGC CUGAUGAGGCCGUUAGGCCGAA AUGCAAAU
9717


1861
GCAUAGCUU CCAAUAAA
299
UUUAUUGG CUGAUGAGGCCGUUAGGCCGAA AGCUAUGC
9718


1862
CAUAGCUUC CAAUAAAG
300
CUUUAUUG CUGAUGAGGCCGUUAGGCCGAA AAGCUAUG
9719


1867
CUUCCAAUA AAGUUGGG
301
CCCAACUU CUGAUGAGGCCGUUAGGCCGAA AUUGGAAG
9720


1872
AAUAAAGUU GGGACUGU
302
ACAGUCCC CUGAUGAGGCCGUUAGGCCGAA ACUUUAUU
9721


1893
AGAAACAUA AGCUUUUA
303
UAAAAGCU CUGAUGAGGCCGUUAGGCCGAA AUGUUUCU
9722


1898
CAUAAGCUU UUAUAUCA
304
UGAUAUAA CUGAUGAGGCCGUUAGGCCGAA AGCUUAUG
9723


1899
AUAAGCUUU UAUAUCAC
305
GUGAUAUA CUGAUGAGGCCGUUAGGCCGAA AAGCUUAU
9724


1900
UAAGCUUUU AUAUCACA
306
UGUGAUAU CUGAUGAGGCCGUUAGGCCGAA AAAGCUUA
9725


1901
AAGCUUUUA UAUCACAG
307
CUGUGAUA CUGAUGAGGCCGUUAGGCCGAA AAAAGCUU
9726


1903
GCUUUUAUA UCACAGAU
308
AUCUGUGA CUGAUGAGGCCGUUAGGCCGAA AUAAAAGC
9727


1905
UUUUAUAUC ACAGAUGU
309
ACAUCUGU CUGAUGAGGCCGUUAGGCCGAA AUAUAAAA
9728


1925
AAAUGGGUU UCAUGUUA
310
UAACAUGA CUGAUGAGGCCGUUAGGCCGAA ACCCAUUU
9729


1926
AAUGGGUUU CAUGUUAA
311
UUAACAUG CUGAUGAGGCCGUUAGGCCGAA AACCCAUU
9730


1927
AUGGGUUUC AUGUUAAC
312
GUUAACAU CUGAUGAGGCCGUUAGGCCGAA AAACCCAU
9731


1932
UUUCAUGUU AACUUGGA
313
UCCAAGUU CUGAUGAGGCCGUUAGGCCGAA ACAUGAAA
9732


1933
UUCAUGUUA ACUUGGAA
314
UUCCAAGU CUGAUGAGGCCGUUAGGCCGAA AACAUGAA
9733


1937
UGUUAACUU GGAAAAAA
315
UUUUUUCC CUGAUGAGGCCGUUAGGCCGAA AGUUAACA
9734


1976
GAAACUGUC UUGCACAG
316
CUGUGCAA CUGAUGAGGCCGUUAGGCCGAA ACAGUUUC
9735


1978
AACUGUCUU GCACAGUU
317
AACUGUGC CUGAUGAGGCCGUUAGGCCGAA AGACAGUU
9736


1986
UGCACAGUU AACAAGUU
318
AACUUGUU CUGAUGAGGCCGUUAGGCCGAA ACUGUGCA
9737


1987
GCACAGUUA ACAAGUUC
319
GACCUUGU CUGAUGAGGCCGUUAGGCCGAA AACUGUGC
9738


1994
UAACAAGUU CUUAUACA
320
UGUAUAAG CUGAUGAGGCCGUUAGGCCGAA ACUUGUUA
9739


1995
AACAAGUUC UUAUACAG
321
CUGUAUAA CUGAUGAGGCCGUUAGGCCGAA AACUUGUU
9740


1997
CAAGUUCUU AUACAGAG
322
CUCUGUAU CUGAUGAGGCCGUUAGGCCGAA AGAACUUG
9741


1998
AAGUUCUUA UACAGAGA
323
UCUCUGUA CUGAUGAGGCCGUUAGGCCGAA AAGAACUU
9742


2000
GUUCUUAUA CAGAGACG
324
CGUCUCUG CUGAUGAGGCCGUUAGGCCGAA AUAAGAAC
9743


2010
AGAGACCUU ACUUGGAU
325
AUCCAAGU CUGAUGAGGCCGUUAGGCCGAA ACGUCUCU
9744


2011
GAGACGUUA CUUGGAUU
326
AAUCCAAG CUGAUGAGGCCGUUAGGCCGAA AACGUCUC
9745


2014
ACGUUACUU GGAUUUUA
327
UAAAAUCC CUGAUGAGGCCGUUAGGCCGAA AGUAACGU
9746


2019
ACUUGGAUU UUACUGCG
328
CGCAGUAA CUGAUGAGGCCGUUAGGCCGAA AUCCAAGU
9747


2020
CUUGGAUUU UACUGCGG
329
CCGCAGUA CUGAUGAGGCCGUUAGGCCGAA AAUCCAAG
9748


2021
UUGGAUUUU ACUGCGGA
330
UCCGCAGU CUGAUGAGGCCGUUAGGCCGAA AAAUCCAA
9749


2022
UGGAUUUUA CUGGGGAC
331
GUCCGCAG CUGAUGAGGCCGUUAGGCCGAA AAAAUCCA
9750


2034
CGGACAGUU AAUAACAG
332
CUGUUAUU CUGAUGAGGCCGUUAGGCCGAA ACUGUCUG
9751


2035
GGACAGUUA AUAACAGA
333
UCUGUUAU CUGAUGAGGCCGUUAGGCCGAA AACUGUCC
9752


2038
CAGUUAAUA ACAGAACA
334
UGUUCUGU CUGAUGAGGCCGUUAGGCCGAA AUUAACUG
9753


2054
AAUGCACUA CAGUAUUA
335
UAAUACUG CUGAUGAGGCCGUUAGGCCGAA AGUGCAUU
9754


2059
ACUACAGUA UUAGCAAG
336
CUUGCUAA CUGAUGAGGCCGUUAGGCCGAA ACUGUAGU
9755


2061
UACAGUAUU AGCAAGCA
337
UGCUUGCU CUGAUGAGGCCGUUAGGCCGAA AUACUGUA
9756


2062
ACAGUAUUA GCAAGCAA
338
UUGCUUGC CUGAUGAGGCCGUUAGGCCGAA AAUACUGU
9757


2082
AUGGCCAUC ACUAAGGA
339
UCCUUAGU CUGAUGAGGCCGUUAGGCCGAA AUGGCCAU
9758


2086
CCAUCACUA AGGAGCAC
340
GUGCUCCU CUGAUGAGGCCGUUAGGCCGAA AGUGAUGG
9759


2096
GGAGCACUC CAUCACUC
341
GAGUGAUG CUGAUGAGGCCGUUAGGCCGAA AGUGCUCC
9760


2100
CACUCCAUC ACUCUUAA
342
UUAAGAGU CUGAUGAGGCCGUUAGGCCGAA AUGGAGUG
9761


2104
CCAUCACUC UUAAUCUU
343
AAGAUUAA CUGAUGAGGCCGUUAGGCCGAA AGUGAUGG
9762


2106
AUCACUCUU AAUCUUAC
344
GUAAGAUU CUGAUGAGGCCGUUAGGCCGAA AGAGUGAU
9763


2107
UCACUCUUA AUCUUACC
345
GGUAAGAU CUGAUGAGGCCGUUAGGCCGAA AAGAGUGA
9764


2110
CUCUUAAUC UUACCAUC
346
GAUGGUAA CUGAUGAGGCCGUUAGGCCGAA AUUAAGAG
9765


2112
CUUAAUCUU ACCAUCAU
347
AUGAUGGU CUGAUGAGGCCGUUAGGCCGAA AGAUUAAG
9766


2113
UUAAUCUUA CCAUCAUG
348
CAUGAUGG CUGAUGAGGCCGUUAGGCCGAA AAGAUUAA
9767


2118
CUUACCAUC AUGAAUGU
349
ACAUUCAU CUGAUGAGGCCGUUAGGCCGAA AUGGUAAG
9768


2127
AUGAAUGUU UCCCUGCA
350
UGCAGGGA CUGAUGAGGCCGUUAGGCCGAA ACAUUCAU
9769


2128
UGAAUGUUU CCCUGCAA
351
UUGCAGGG CUGAUGAGGCCGUUAGGCCGAA AACAUUCA
9770


2129
GAAUGUUUC CCUGCAAG
352
CUUGCAGG CUGAUGAGGCCGUUAGGCCGAA AAACAUUC
9771


2140
UGCAAGAUU CAGGCACC
353
GGUGCCUG CUGAUGAGGCCGUUAGGCCGAA AUCUUGCA
9772


2141
GCAAGAUUC AGGCACCU
354
AGCUGCCU CUGAUGAGGCCGUUAGGCCGAA AAUCUUGC
9773


2150
AGGCACCUA UGCCUGCA
355
UGCAGGCA CUGAUGAGGCCGUUAGGCCGAA AGGUCCCU
9774


2172
AGGAAUGUA UACACAGG
356
CCUGUGUA CUGAUGAGGCCGUUAGGCCGAA ACAUUCCU
9775


2174
GAAUGUAUA CACAGGGG
357
CCCCUGUG CUGAUGAGGCCGUUAGGCCGAA AUACAUUC
9776


2190
GAAGAAAUC CUCCAGAA
358
UUCUGGAG CUGAUGAGGCCGUUAGGCCGAA AUUUCUUC
9777


2193
GAAAUCCUC CAGAAGAA
359
UUCUUCUC CUGAUGAGGCCGUUAGGCCGAA AGGAUUUC
9778


2208
AAAGAAAUU ACAAUCAG
360
CUGAUUGU CUGAUGAGGCCGUUAGGCCGAA AUUUCUUU
9779


2209
AAGAAAUUA CAAUCAGA
361
UCUGAUUG CUGAUGAGGCCGUUAGGCCGAA AAUUUCUU
9780


2214
AUUACAAUC AGAGAUCA
362
UGAUCUCU CUGAUGAGGCCGUUAGGCCGAA AUUGUAAU
9781


2221
UCAGAGAUC AGGAAGCA
363
UGCUUCCU CUGAUGAGGCCGUUAGGCCGAA AUCUCUGA
9782


2234
AGCACCAUA CCUCCUGC
364
GCAGGAGG CUGAUGAGGCCGUUAGGCCGAA AUGGUGCU
9783


2238
CCAUACCUC CUGCGAAA
365
UUUCGCAG CUGAUGAGGCCGUUAGGCCGAA AGGUAUGG
9784


2250
CGAAACCUC AGUGAUCA
366
UGAUCACU CUGAUGAGGCCGUUAGGCCGAA AGGUUUCG
9785


2257
UCAGUGAUC ACACAGUG
367
CACUGUGU CUGAUGAGGCCGUUAGGCCGAA AUCACUGA
9786


2271
GUGGCCAUC AGCAGUUC
368
GAACUGCU CUGAUGAGGCCGUUAGGCCGAA AUGGCCAC
9787


2278
UCAGCAGUU CCACCACU
369
AGUGGUGG CUGAUGAGGCCGUUAGGCCGAA ACUGCUGA
9788


2279
CAGCAGUUC CACCACUU
370
AAGUGGUG CUGAUGAGGCCGUUAGGCCGAA AACUGCUG
9789


2287
CCACCACUU UAGACUGU
371
ACAGUCUA CUGAUGAGGCCGUUAGGCCGAA AGUGGUGG
9790


2288
CACCACUUU AGACUGUC
372
GACAGUCU CUGAUGAGGCCGUUAGGCCGAA AAGUGGUG
9791


2289
ACCACUUUA GACUGUCA
373
UGACAGUC CUGAUGAGGCCGUUAGGCCGAA AAAGUGGU
9792


2296
UAGACUGUC AUGCUAAU
374
AUUAGCAU CUGAUGAGGCCGUUAGGCCGAA ACAGUCUA
9793


2302
GUCAUGCUA AUGGUGUC
375
GACACCAU CUGAUGAGGCCGUUAGGCCGAA AGCAUGAC
9794


2310
AAUGGUGUC CCCGAGCC
376
GGCUCGGG CUGAUGAGGCCGUUAGGCCGAA ACACCAUU
9795


2320
CCGAGCCUC AGAUCACU
377
AGUGAUCU CUGAUGAGGCCGUUAGGCCGAA AGGCUCGG
9796


2325
CCUCAGAUC ACUUGGUU
378
AACCAAGU CUGAUGAGGCCGUUAGGCCGAA AUCUGAGG
9797


2329
AGAUCACUU GGUUUAAA
379
UUUAAACC CUGAUGAGGCCGUUAGGCCGAA AGUGAUCU
9798


2333
CACUUGGUU UAAAAACA
380
UGUUUUUA CUGAUGAGGCCGUUAGGCCGAA ACCAAGUG
9799


2334
ACUUGGUUU AAAAACAA
381
UUGUUUUU CUGAUGAGGCCGUUAGGCCGAA AACCAAGU
9800


2335
CUUGGUUUA AAAACAAC
382
GUUGUUUU CUGAUGAGGCCGUUAGGCCGAA AAACCAAG
9801


2352
CACAAAAUA CAACAAGA
383
UCUUGUUG CUGAUGAGGCCGUUAGGCCGAA AUUUUGUG
9802


2370
CCUGGAAUU AUUUUAGG
384
CCUAAAAU CUGAUGAGGCCGUUAGGCCGAA AUUCCAGG
9803


2371
CUGGAAUUA UUUUAGGA
385
UCCUAAAA CUGAUGAGGCCGUUAGGCCGAA AAUUCCAG
9804


2373
GGAAUUAUU UUAGGACC
386
GGUCCUAA CUGAUGAGGCCGUUAGGCCGAA AUAAUUCC
9805


2374
GAAUUAUUU UAGGACCA
387
UGGUCCUA CUGAUGAGGCCGUUAGGCCGAA AAUAAUUC
9806


2375
AAUUAUUUU AGGACCAG
388
CUGGUCCU CUGAUGAGGCCGUUAGGCCGAA AAAUAAUU
9807


2376
AUUAUUUUA GGACCAGG
389
CCUGGUCC CUGAUGAGGCCGUUAGGCCGAA AAAAUAAU
9808


2399
CACGCUGUU UAUUGAAA
390
UUUCAAUA CUGAUGAGGCCGUUAGGCCGAA ACAGCGUG
9809


2400
ACGCUGUUU AUUGAAAG
391
CUUUCAAU CUGAUGAGGCCGUUAGGCCGAA AACAGCGU
9810


2401
CGCUGUUUA UUGAAAGA
392
UCUUUCAA CUGAUGAGGCCGUUAGGCCGAA AAACAGCG
9811


2403
CUGUUUAUU GAAAGAGU
393
ACUCUUUC CUGAUGAGGCCGUUAGGCCGAA AUAAACAG
9812


2412
GAAAGAGUC ACAGAAGA
394
UCUUCUGU CUGAUGAGGCCGUUAGGCCGAA ACUCUUVC
9813


2433
GAAGGUGUC UAUCACUG
395
CAGUGAUA CUGAUGAGGCCGUUAGGCCGAA ACACCUUC
9814


2435
AGGUGUCUA UCACUGCA
396
UGCAGUGA CUGAUGAGGCCGUUAGGCCGAA AGACACCU
9815


2437
GUGUCUAUC ACUGCAAA
397
UUUGCAGU CUGAUGAGGCCGUUAGGCCGAA AUAGACAC
9816


2465
GAAGGGCUC UGUGGAAA
398
UUUCCACA CUGAUGAGGCCGUUAGGCCGAA AGCCCUUC
9817


2476
UGGAAAGUU CAGCAUAC
399
GUAUGCUG CUGAUGAGGCCGUUAGGCCGAA ACUUUCCA
9818


2477
GGAAAGUUC AGCAUACC
400
GGUAUGCU CUGAUGAGGCCGUUAGGCCGAA AACUUUCC
9819


2483
UUCAGCAUA CCUCACUG
401
CAGUGAGG CUGAUGAGGCCGUUAGGCCGAA AUGCUGAA
9820


2487
GCAUACCUC ACUGUUCA
402
UGAACAGU CUGAUGAGGCCGUUAGGCCGAA AGGUAUGC
9821


2493
CUCACUGUU CAAGGAAC
403
GUUCCUUG CUGAUGAGGCCGUUAGGCCGAA ACAGUGAG
9822


2494
UCACUGUUC AAGGAACC
404
GGUUCCUU CUGAUGAGGCCGUUAGGCCGAA AACAGUGA
9823


2504
AGGAACCUC GGACAAGU
405
ACUUGUCC CUGAUGAGGCCGUUAGGCCGAA AGGUUCCU
9824


2513
GGACAAGUC UAAUCUGG
406
CCAGAUUA CUGAUGAGGCCGUUAGGCCGAA ACUUGUCC
9825


2515
ACAAGUCUA AUCUGGAG
407
CUCCAGAU CUGAUGAGGCCGUUAGGCCGAA AGACUUGU
9826


2518
AGUCUAAUC UGGAGCUG
408
CAGCUCCA CUGAUGAGGCCGUUAGGCCGAA AUUAGACU
9827


2529
GAGCUGAUC ACUCUAAC
409
GUUAGAGU CUGAUGAGGCCGUUAGGCCGAA AUCAGCUC
9828


2533
UGAUCACUC UAACAUGC
410
GCAUGUUA CUGAUGAGGCCGUUAGGCCGAA AGUGAUCA
9829


2535
AUCACUCUA ACAUGCAC
411
GUGCAUGU CUGAUGAGGCCGUUAGGCCGAA AGAGUGAU
9830


2560
CUGCGACUC UCUUCUGG
412
CCAGAAGA CUGAUGAGGCCGUUAGGCCGAA AGUCGCAG
9831


2562
GCGACUCUC UUCUGGCU
413
AGCCAGAA CUGAUGAGGCCGUUAGGCCGAA AGAGUCGC
9832


2564
GACUCUCUU CUGGCUCC
414
GGAGCCAG CUGAUGAGGCCGUUAGGCCGAA AGAGAGUC
9833


2565
ACUCUCUUC UGGCUCCU
415
AGGAGCCA CUGAUGAGGCCGUUAGGCCGAA AAGAGAGU
9834


2571
UUCUGGCUC CUAUUAAC
416
GUUAAUAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGAA
9835


2574
UGGCUCCUA UUAACCCU
417
AGGGUUAA CUGAUGAGGCCGUUAGGCCGAA AGGAGCCA
9836


2576
GCUCCUAUU AACCCUCC
418
GGAGGGUU CUGAUGAGGCCGUUAGGCCGAA AUAGGAGC
9837


2577
CUCCUAUUA ACCCUCCU
419
AGGAGGGU CUGAUGAGGCCGUUAGGCCGAA AAUAGGAG
9838


2583
UUAACCCUC CUUAUCCG
420
CGGAUAAG CUGAUGAGGCCGUUAGGCCGAA AGGGUUAA
9839


2586
ACCCUCCUU AUCCGAAA
421
UUUCGGAU CUGAUGAGGCCGUUAGGCCGAA AGGAGGGU
9840


2587
CCCUCCUUA UCCGAAAA
422
UUUUCGGA CUGAUGAGGCCGUUAGGCCGAA AAGGAGGG
9841


2589
CUCCUUAUC CGAAAAAU
423
AUUUUUCG CUGAUGAGGCCGUUAGGCCGAA AUAAGGAG
9842


2606
GAAAAGGUC UUCUUCUG
424
CAGAAGAA CUGAUGAGGCCGUUAGGCCGAA ACCUUUUC
9843


2608
AAAGGUCUU CUUCUGAA
425
UUCAGAAG CUGAUGAGGCCGUUAGGCCGAA AGACCUUU
9844


2809
AAGGUCUUC UUCUGAAA
426
UUUCAGAA CUGAUGAGGCCGUUAGGCCGAA AAGACCUU
9845


2611
GGUCUUCUU CUGAAAUA
427
UAUUUCAG CUGAUGAGGCCGUUAGGCCGAA AGAAGACC
9846


2612
GUCUUCUUC UGAAAUAA
428
UUAUUUCA CUGAUGAGGCCGUUAGGCCGAA AAGAAGAC
9847


2619
UCUGAAAUA AAGACUGA
429
UCAGUCUU CUGAUGAGGCCGUUAGGCCGAA AUUUCAGA
9848


2630
GACUGACUA CCUAUCAA
430
UUGAUAGG CUGAUGAGGCCGUUAGGCCGAA AGUCAGUC
9849


2634
GACUACCUA UCAAUUAU
431
AUAAUUGA CUGAUGAGGCCGUUAGGCCGAA AGGUAGUC
9850


2636
CUACCUAUC AAUUAUAA
432
UUAUAAUU CUGAUGAGGCCGUUAGGCCGAA AUAGGUAG
9851


2640
CUAUCAAUU AUAAUGGA
433
UCCAUUAU CUGAUGAGGCCGUUAGGCCGAA AUUGAUAG
9852


2641
UAUCAAUUA UAAUGGAC
434
GUCCAUUA CUGAUGAGGCCGUUAGGCCGAA AAUUGAUA
9853


2643
UCAAUUAUA AUGGACCC
435
GGGUCCAU CUGAUGAGGCCGUUAGGCCGAA AUAAUUGA
9854


2661
GAUGAAGUU CCUUUGGA
436
UCCAAAGG CUGAUGAGGCCGUUAGGCCGAA ACUUCAUC
9855


2662
AUGAAGUUC CUUUGGAU
437
AUCCAAAG CUGAUGAGGCCGUUAGGCCGAA AACUUCAU
9856


2665
AAGUUCCUU UGGAUGAG
438
CUCAUCCA CUGAUGAGGCCGUUAGGCCGAA AGGAACUU
9857


2666
AGUUCCUUU GGAUGAGC
439
GCUCAUCC CUGAUGAGGCCGUUAGGCCGAA AAGGAACU
9858


2688
GAGCGGCUC CCUUAUGA
440
UCAUAAGG CUGAUGAGGCCGUUAGGCCGAA AGCCGCUC
9859


2692
GGCUCCCUU AUGAUGCC
441
GGCAUCAU CUGAUGAGGCCGUUAGGCCGAA AGGGAGCC
9860


2693
GCUCCCUUA UGAUGCCA
442
UGGCAUCA CUGAUGAGGCCGUUAGGCCGAA AAGGGAGC
9861


2714
GUGGGAGUU UGCCCGGG
443
CCCGGGCA CUGAUGAGGCCGUUAGGCCGAA ACUCCCAC
9862


2715
UGGGAGUUU GCCCGGGA
444
UCCCGGGC CUGAUGAGGCCGUUAGGCCGAA AACUCCCA
9863


2730
GAGAGACUU AAACUGGG
445
CCCAGUUU CUGAUGAGGCCGUUAGGCCGAA AGUCUCUC
9864


2731
AGAGACUUA AACUGGCC
446
GCCCAGUU CUGAUGAGGCCGUUAGGCCGAA AAGUCUCU
9865


2744
GGGCAAAUC ACUUGGAA
447
UUCCAAGU CUGAUGAGGCCGUUAGGCCGAA AUUUGCCC
9866


2748
AAAUCACUU GGAAGAGG
448
CCUCUUCC CUGAUGAGGCCGUUAGGCCGAA AGUGAUUU
9867


2761
GAGGGGCUU UUGGAAAA
449
UUUUCCAA CUGAUGAGGCCGUUAGGCCGAA AGCCCCUC
9868


2762
AGGGGCUUU UGGAAAAG
450
CUUUUCCA CUGAUGAGGCCGUUAGGCCGAA AAGCCCCU
9869


2763
GGGGCUUUU GGAAAAGU
451
ACUUUUCC CUGAUGAGGCCGUUAGGCCGAA AAAGCCCC
9870


2775
AAAGUGGUU CAAGCAUC
452
GAUGCUUG CUGAUGAGGCCGUUAGGCCGAA ACCACUUU
9871


2776
AAGUGGUUC AAGCAUCA
453
UGAUGCUU CUGAUGAGGCCGUUAGGCCGAA AACCACUU
9872


2783
UCAAGCAUC AGCAUUUG
454
CAAAUGCU CUGAUGAGGCCGUUAGGCCGAA AUGCUUGA
9873


2789
AUCAGCAUU UGGCAUUA
455
UAAUGCCA CUGAUGAGGCCGUUAGGCCGAA AUGCUGAU
9874


2790
UCAGCAUUU GGCAUUAA
456
UUAAUGCC CUGAUGAGGCCGUUAGGCCGAA AAUGCUGA
9875


2796
UUUGGCAUU AAGAAAUC
457
GAUUUCUU CUGAUGAGGCCGUUAGGCCGAA AUGCCAAA
9876


2797
UUGGCAUUA AGAAAUCA
458
UGAUUUCU CUGAUGAGGCCGUUAGGCCGAA AAUGCCAA
9877


2804
UAAGAAAUC ACCUACGU
459
ACGUAGGU CUGAUGAGGCCGUUAGGCCGAA AUUUCUUA
9878


2809
AAUCACCUA CGUGCCGG
460
CCGGCACG CUGAUGAGGCCGUUAGGCCGAA AGGUCAUU
9879


2864
CAGCGAGUA CAAAGCUC
461
GAGCUUUG CUGAUGAGGCCGUUAGGCCGAA ACUCGCUG
9880


2872
ACAAAGCUC UGAUGACU
462
AGUCAUCA CUGAUGAGGCCGUUAGGCCGAA AGCUUUGU
9881


2886
ACUGAGCUA AAAAUCUU
463
AAGAUUUU CUGAUGAGGCCGUUAGGCCGAA AGCUCAGU
9882


2892
CUAAAAAUC UUGACCCA
464
UGGGUCAA CUGAUGAGGCCGUUAGGCCGAA AUUUUUAG
9883


2894
AAAAAUCUU GACCCACA
465
UGUGOGUC CUGAUGAGGCCGUUAGGCCGAA AGAUUUUU
9884


2904
ACCCACAUU GGCCACCA
466
UGGUGGCC CUGAUGAGGCCGUUAGGCCGAA AUGUGGGU
9885


2914
GCCACCAUC UGAACGUG
467
CACGUUCA CUGAUGAGGCCGUUAGGCCGAA AUGGUGGC
9886


2925
AACGUGGUU AACCUGCU
468
AGCAGGUU CUGAUGAGGCCGUUAGGCCGAA ACCACGUU
9887


2926
ACGUGGUUA ACCUGCUG
469
CAGCAGGU CUGAUGAGGCCGUUAGGCCGAA AACCACGU
9888


2962
GAGGGCCUC UGAUGGUG
470
CACCAUCA CUGAUGAGGCCGUUAGGCCGAA AGGCCCUC
9889


2973
AUGGUGAUU GUUGAAUA
471
UAUUCAAC CUGAUGAGGCCGUUAGGCCGAA AUCACCAU
9890


2976
GUGAUUGUU GAAUACUG
472
CAGUAUUC CUGAUGAGGCCGUUAGGCCGAA ACAAUCAC
9891


2981
UGUUGAAUA CUGCAAAU
473
AUUUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUCAACA
9892


2990
CUGCAAAUA UGGAAAUC
474
GAUUUCCA CUGAUGAGGCCGUUAGGCCGAA AUUUGCAG
9893


2998
AUGGAAAUC UCUCCAAC
475
GUUGGAGA CUGAUGAGGCCGUUAGGCCGAA AUUUCCAU
9894


3000
GGAAAUCUC UCCAACUA
476
UAGUUGGA CUGAUGAGGCCGUUAGGCCGAA AGAUUUCC
9895


3002
AAAUCUCUC CAACUACC
477
GGUAGUUG CUGAUGAGGCCGUUAGGCCGAA AGAGAUUU
9896


3008
CUCCAACUA CCUCAAGA
478
UCUUGAGG CUGAUGAGGCCGUUAGGCCGAA AGUUGGAG
9897


3012
AACUACCUC AAGAGCAA
479
UUGCUCUU CUGAUGAGGCCGUUAGGCCGAA AGGUAGUU
9898


3029
ACGUGACUU AUUUUUUC
480
GAAAAAAU CUGAUGAGGCCGUUAGGCCGAA AGUCACGU
9899


3030
CGUGACUUA UUUUUUCU
481
AGAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAGUCACG
9900


3032
UGACUUAUU UUUUCUCA
482
UGAGAAAA CUGAUGAGGCCGUUAGGCCGAA AUAAGUCA
9901


3033
GACUUAUUU UUUCUCAA
483
UUGAGAAA CUGAUGAGGCCGUUAGGCCGAA AAUAAGUC
9902


3034
ACUUAUUUU UUCUCAAC
484
GUUGAGAA CUGAUGAGGCCGUUAGGCCGAA AAAUAAGU
9903


3035
CUUAUUUUU UCUCAACA
485
UGUUGAGA CUGAUGAGGCCGUUAGGCCGAA AAAAUAAG
9904


3036
UUAUUUUUU CUCAACAA
486
UUGUUGAG CUGAUGAGGCCGUUAGGCCGAA AAAAAUAA
9905


3037
UAUUUUUUC UCAACAAG
487
CUUGUUGA CUGAUGAGGCCGUUAGGCCGAA AAAAAAUA
9906


3039
UUUUUUCUC AACAAGGA
488
UCCUUGUU CUGAUGAGGCCGUUAGGCCGAA AGAAAAAA
9907


3057
GCAGCACUA CACAUGGA
489
UCCAUGUG CUGAUGAGGCCGUUAGGCCGAA AGUGCUGC
9908


3070
UGGAGCCUA AGAAAGAA
490
UUCUUUCU CUGAUGAGGCCGUUAGGCCGAA AGGCUCCA
9909


3120
CCAAGACUA GAUAGCGU
491
ACGCUAUC CUGAUGAGGCCGUUAGGCCGAA AGUCUUGG
9910


3124
GACUAGAUA GCGUCACC
492
GGUGACGC CUGAUGAGGCCGUUAGGCCGAA AUCUAGUC
9911


3129
GAUAGCGUC ACCAGCAG
493
CUGCUGGU CUGAUGAGGCCGUUAGGCCGAA ACGCUAUC
9912


3146
CGAAAGCUU UGCGAGCU
494
AGCUCGCA CUGAUGAGGCCGUUAGGCCGAA AGCUUUCG
9913


3147
GAAAGCUUU GCGAGCUC
495
GAGCUCGC CUGAUGAGGCCGUUAGGCCGAA AAGCUUUC
9914


3155
UGCGAGCUC CGGCUUUC
496
GAAAGCCG CUGAUGAGGCCGUUAGGCCGAA AGCUCGCA
9915


3161
CUCCGGCUU UCAGGAAG
497
CUUCCUGA CUGAUGAGGCCGUUAGGCCGAA AGCCGGAG
9916


3162
UCCGGCUUU CAGGAAGA
498
UCUUCCUG CUGAUGAGGCCGUUAGGCCGAA AAGCCGGA
9917


3163
CCGGCUUUC AGGAAGAU
499
AUCUUCCU CUGAUGAGGCCGUUAGGCCGAA AAAGCCGG
9918


3172
AGGAAGAUA AAAGUCUG
500
CAGACUUU CUGAUGAGGCCGUUAGGCCGAA AUCUUCCU
9919


3178
AUAAAAGUC UGAGUGAG
501
AUCACUCA CUGAUGAGGCCGUUAGGCCGAA ACUUUUAU
9920


3189
AGUGAUGUU GAGGAAGA
502
UCUUCCUC CUGAUGAGGCCGUUAGGCCGAA ACAUCACU
9921


3205
AGGAGGAUU CUGACGGU
503
ACCGUCAG CUGAUGAGGCCGUUAGGCCGAA AUCCUCCU
9922


3206
UGAGGAUUC UGACGGUU
504
AACCGUCA CUGAUGAGGCCGUUAGGCCGAA AAUCCUCC
9923


3214
CUGACUGUU UCUACAAG
505
CUUGUAGA CUGAUGAGGCCGUUAGGCCGAA ACCGUCAG
9924


3215
UGACGGUUU CUACAAGG
506
CCUUGUAG CUGAUGAGGCCGUUAGGCCGAA AACCGUCA
9925


3216
GACGGUUUC UACAAGGA
507
UCCUGGUA CUGAUGAGGCCGUUAGGCCGAA AAACCGUC
9926


3218
CGGUUUCUA CAAGGAGC
508
GCUCCUUG CUGAUGAGGCCGUUAGGCCGAA AGAAACCG
9927


3231
GAGCCCAUC ACUAUGGA
509
UCCAUAGU CUGAUGAGGCCGUUAGGCCGAA AUGGGCUC
9928


3235
CCAUCACUA UGGAAGAU
510
AUCUUCCA CUGAUGAGGCCGUUAGGCCGAA AGUGAUGG
9929


3244
UGGAAGAUC UGAUUUCU
511
AGAAAUCA CUGAUGAGGCCGUUAGGCCGAA AUCUUCCA
9930


3249
GAUCUGAUG UCUGACAG
512
CUGUAAGA CUGAUGAGGCCGUUAGGCCGAA AUCAGAUC
9931


3250
AUCUGAUUU CUUACAGU
513
ACUGUAAG CUGAUGAGGCCGUUAGGCCGAA AAUCAGAU
9932


3251
UCUGAUUUC UUACAGUU
514
AACUGUAA CUGAUGAGGCCGUUAGGCCGAA AAAUCAGA
9933


3253
UGAUUUCUU ACAGUUUU
515
AAAACUGU CUGAUGAGGCCGUUAGGCCGAA AGAAAUCA
9934


3254
GAUUUCUUA CAGUUUUC
516
GAAAACUG CUGAUGAGGCCGUUAGGCCGAA AAGAAAUC
9935


3259
CUUACAGUU UUCAAGUG
517
CACUUGAA CUGAUGAGGCCGUUAGGCCGAA ACUGUAAG
9936


3260
UUACAGUUU UCAAGUGG
518
CCACUUGA CUGAUGAGGCCGUUAGGCCGAA AACUGUAA
9937


3261
UACAGUUUU CAAGUGGC
519
GCCACUUG CUGAUGAGGCCGUUAGGCCGAA AAACUGUA
9938


3262
ACAGUUUUC AAGUGGCC
520
GGCCACUU CUGAUGAGGCCGUUAGGCCGAA AAAACUGU
9939


3284
CAUGGAGUU CCUGUCUU
521
AAGACAGG CUGAUGAGGCCGUUAGGCCGAA ACUCCAUG
9940


3285
AUGGAGUUC CUGUCUUC
522
GAAGACAG CUGAUGAGGCCGUUAGGCCGAA AACUCCAU
9941


3290
GUUCCUGUC UUCCAGAA
523
UUCUGGAA CUGAUGAGGCCGUUAGGCCGAA ACAGGAAC
9942


3292
UCCUGUCUU CCAGAAAG
524
CUUUCUGG CUGAUGAGGCCGUUAGGCCGAA AGACAGGA
9943


3293
CCUGUCUUC CAGAAAGU
525
ACUUUCUG CUGAUGAGGCCGUUAGGCCGAA AAGACAGG
9944


3306
AAGUGCAUU CAUCGGGA
526
UCCCGAUG CUGAUGAGGCCGUUAGGCCGAA AUGCACUU
9945


3307
AGUGCAUUC AUCGGGAC
527
GUCCCGAU CUGAUGAGGCCGUUAGGCCGAA AAUGCACU
9946


3310
GCAUUCAUC GGGACCUG
528
CAGGUCCC CUGAUGAGGCCGUUAGGCCGAA AUGAAUGC
9947


3333
AGAAACAUU CUUUUAUC
529
GAUAAAAG CUGAUGAGGCCGUUAGGCCGAA AUGUUUCU
9948


3334
GAAACAUUC UUUUAUCU
530
AGAUAAAA CUGAUGAGGCCGUUAGGCCGAA AAUGUUUC
9949


3336
AACAUUCUU UUAUCUGA
531
UCAGAUAA CUGAUGAGGCCGUUAGGCCGAA AGAAUGUU
9950


3337
ACAUUCUUU UAUCUGAG
532
CUCAGAUA CUGAUGAGGCCGUUAGGCCGAA AAGAAUGU
9951


3338
CAUUCUUUU AUCUGAGA
533
UCUCAGAU CUGAUGAGGCCGUUAGGCCGAA AAAGAAUG
9952


3339
AUUCUUUUA UCUGAGAA
534
UUCUCAGA CUGAUGAGGCCGUUAGGCCGAA AAAAGAAU
9953


3341
UCUUUUAUC UGAGAACA
535
UGUUCUCA CUGAUGAGGCCGUUAGGCCGAA AUAAAAGA
9954


3363
GUGAAGAUU UGUGAUUU
536
AAAUCACA CUGAUGAGGCCGUUAGGCCGAA AUCUUCAC
9955


3364
UGAAGAUUU GUGAUUUG
537
AAAAUCAC CUGAUGAGGCCGUUAGGCCGAA AAUCUUCA
9956


3370
UUUGUGAUU UUGGCCUU
538
AAGGCCAA CUGAUGAGGCCGUGAGGCCGAA AUCACAAA
9957


3371
UUGUGAUUU UGGCCUUG
539
CAAGGCCA CUGAUGAGGCCGUUAGGCCGAA AAUCACAA
9958


3372
UGUGAUUUU GGCCUUGC
540
GCAAGGCC CUGAUGAGGCCGUUAGGCCGAA AAAUCACA
9959


3378
UUUGGCCUU GCCCGGGA
541
UCCCGGGC CUGAUGAGGCCGUUAGGCCGAA AGGCCAAA
9960


3388
CCCGGGAUA UUUAUAAG
542
CUUAUAAA CUGAUGAGGCCGUUAGGCCGAA AUCCCGGG
9961


3390
CGGGAUAUU UAUAAGAA
543
UUCUUAUA CUGAUGAGGCCGUUAGGCCGAA AUAUCCCG
9962


3391
GGGAUAUUU AUAAGAAC
544
GUUCUUAU CUGAUGAGGCCGUUAGGCCGAA AAUAUCCC
9963


3392
GGAUAUUUA UAAGAACC
545
GGUUCUUA CUGAUGAGGCCGUUAGGCCGAA AAAUAUCC
9964


3394
AUAUUUAUA AGAACCCC
546
GGGGUUCU CUGAUGAGGCCGUUAGGCCGAA AUAAAUAU
9965


3406
ACCCCGAUU AUGUGAGA
547
UCUCACAU CUGAUGAGGCCGUUAGGCCGAA AUCGGGGU
9966


3407
CCCCGAUUA UGUGAGAA
548
UUCUCACA CUGAUGAGGCCGUUAGGCCGAA AAUCGGGG
9967


3424
AAGGAGAUA CUCGACUU
549
AAGUCGAG CUGAUGAGGCCGUUAGGCCGAA AUCUCCUU
9968


3427
GAGAUACUC GACUUCCU
550
AGGAAGUC CUGAUGAGGCCGUUAGGCCGAA AGUAUCUC
9969


3432
ACUCGACUU CCUCUGAA
551
UUCAGAGG CUGAUGAGGCCGUUAGGCCGAA AGUCGAGU
9970


3433
CUCGACUUC CUCUGAAA
552
UUUCAGAG CUGAUGAGGCCGUUAGGCCGAA AAGUCGAG
9971


3436
GACUUCCUC UGAAAUGG
553
CCAUUUCA CUGAUGAGGCCGUUAGGCCGAA AGGAAGUC
9972


3451
GGAUGGCUC CCGAAUCU
554
AGAUUCGG CUGAUGAGGCCGUUAGGCCGAA AGCCAUCC
9973


3458
UCCCGAAUC UAUCUUUG
555
CAAAGAUA CUGAUGAGGCCGUUAGGCCGAA AUUCGGGA
9974


3460
CCGAAUCUA UCUUUGAC
556
GUCAAAGA CUGAUGAGGCCGUUAGGCCGAA AGAUUCGG
9975


3462
GAAUCUAUC UUUGACAA
557
UUGUCAAA CUGAUGAGGCCGUUAGGCCGAA AUAGAUUC
9976


3464
AUCUAUCUU UGACAAAA
558
UUUUGUCA CUGAUGAGGCCGUUAGGCCGAA AGAUAGAU
9977


3465
UCUAUCUUU GACAAAAU
559
AUUUUGUC CUGAUGAGGCCGUUAGGCCGAA AAGAUAGA
9978


3474
GACAAAAUC UACAGCAC
560
GUGCUGUA CUGAUGAGGCCGUUAGGCCGAA AUUUUGUC
9979


3476
CAAAAUCUA CAGGACCA
561
UGGUGCUG CUGAUGAGGCCGUUAGGCCGAA AGAUUUUG
9980


3500
CGUGUGGUC UUACGGAG
562
CUCCGUAA CUGAUGAGGCCGUUAGGCCGAA ACCACACG
9981


3502
UGUGGUCUU ACGGAGUA
563
UACUCCGU CUGAUGAGGCCGUUAGGCCGAA AGACCACA
9982


3503
GUGGUCUUA CGGAGUAU
564
AUACUCCG CUGAUGAGGCCGUUAGGCCGAA AAGACCAC
9983


3510
UACGGAGUA UUGCUGUG
565
CACAGCAA CUGAUGAGGCCGUUAGGCCGAA ACUCCGUA
9984


3512
CGGAGUAUU GCUGUGGG
566
CCCACAGC CUGAUGAGGCCGUUAGGCCGAA AUACUCCG
9985


3525
UGGGAAAUC UUCUCCUU
567
AAGGAGAA CUGAUGAGGCCGUUAGGCCGAA AUUUCCCA
9986


3527
GGAAAUCUU CUCCUUAG
568
CUAAGGAG CUGAUGAGGCCGUUAGGCCGAA AGAUUUCC
9987


3528
GAAAUCUUC UCCUUAGG
569
CCUAAGGA CUGAUGAGGCCGUUAGGCCGAA AAGAUUUC
9988


3530
AAUCUUCUC CUUAGGUG
570
CACCUAAG CUGAUGAGGCCGUUAGGCCGAA AGAAGAUU
9989


3533
CUUCUCCUU AGGUGGGU
571
ACCCACCU CUGAUGAGGCCGUUAGGCCGAA AGGAGAAG
9990


3534
UUCUCCUUA GGUGGGUC
572
GACCCACC CUGAUGAGGCCGUUAGGCCGAA AAGGAGAA
9991


3542
AGGUOGGUC UCCAUACC
573
GGUAUGGA CUGAUGAGGCCGUUAGGCCGAA ACCCACCU
9992


3544
GUGGGUCUC CAUACCCA
574
UGGGUAUG CUGAUGAGGCCGUUAGGCCGAA AGACCCAC
9993


3548
GUCUCCAUA CCCAGGAG
575
CUCCUGGG CUGAUGAGGCCGUUAGGCCGAA AUGGAGAC
9994


3558
CCAGGAGUA CAAAUGGA
576
UCCAUUUG CUGAUGAGGCCGUUAGGCCGAA ACUCCUGG
9995


3575
UGAGGACUU UUGCAGUC
577
GACUGCAA CUGAUGAGGCCGUUAGGCCGAA AGUCCUCA
9996


3576
GAGGACUUU UGCAGUCG
578
CGACUGCA CUGAUGAGGCCGUUAGGCCGAA AAGUCCUC
9997


3577
AGGACUUUU GCAGUCGC
579
GCGACUGC CUGAUGAGGCCGUUAGGCCGAA AAAGUCCU
9998


3583
UUUGCAGUC GCCUGAGG
580
CCUCAGGC CUGAUGAGGCCGUUAGGCCGAA ACUGCAAA
9999


3613
UGAGAGCUC CUGAGUAC
581
GUACUCAG CUGAUGAGGCCGUUAGGCCGAA ACCUCUCA
10000


3620
UCCUGAGUA CUCUACUC
582
GAGUAGAG CUGAUGAGGCCGUUAGGCCGAA ACUCAGGA
10001


3623
UGAGUACUC UACUCCUG
583
CAGGAGUA CUGAUGAGGCCGUUAGGCCGAA AGUACUCA
10002


3625
AGUACUCUA CUCCUGAA
584
UUCAGGAG CUGAUGAGGCCGUUAGGCCGAA AGAGUACU
10003


3628
ACUCUACUC CUGAAAUC
585
GAUUUCAG CUGAUGAGGCCGUUAGGCCGAA AGUAGAGU
10004


3636
CCUGAAAUC UAUCAGAU
586
AUCUGAUA CUGAUGAGGCCGUUAGGCCGAA AUUUCAGG
10005


3638
UGAAAUCUA UCAGAUCA
587
UGAUCUGA CUGAUGAGGCCGUUAGGCCGAA AGAUUUCA
10006


3640
AAAUCUAUC AGAUCAUG
588
CAUGAUCU CUGAUGAGGCCGUUAGGCCGAA AUAGAUUU
10007


3645
UAUCAGAUC AUGCUGGA
589
UCCAGCAU CUGAUGAGGCCGUUAGGCCGAA AUCUGAUA
10008


3689
GCCAAGAUU UGCAGAAC
590
GUUCUGCA CUGAUGAGGCCGUUAGGCCGAA AUCUUGGC
10009


3690
CCAAGAUUU GCAGAACU
591
AGUUCUGC CUGAUGAGGCCGUUAGGCCGAA AAUCUUGG
10010


3699
GCAGAACUU GUGGAAAA
592
UUUUCCAC CUGAUGAGGCCGUUAGGCCGAA AGUUCUGC
10011


3711
GAAAAACUA GGUGAUUU
593
AAAUCACC CUGAUGAGGCCGUUAGGCCGAA AGUUUUUC
10012


3718
UAGGUGAUU UGCUUCAA
594
UUGAAGCA CUGAUGAGGCCGUUAGGCCGAA AUCACCUA
10013


3719
AGGUGAUUU GCUUCAAG
595
CUUGAACC CUGAUGAGGCCGUUAGGCCGAA AAUCACCU
10014


3723
GAUUUGCUU CAAGCAAA
596
UUUGCUUG CUGAUGAGGCCGUUAGGCCGAA AGCAAAUC
10015


3724
AUUUGCUUC AAGCAAAU
597
AUUUGCUU CUGAUGAGGCCGUUAGGCCGAA AAGCAAAU
10016


3735
GCAAAUGUA CAACAGGA
598
UCCUGUUG CUGAUGAGGCCGUUAGGCCGAA ACAUUUGC
10017


3748
AGGAUGGUA AAGACUAC
599
GUAGUCUU CUGAUGAGGCCGUUAGGCCGAA ACCAUCCU
10018


3755
UAAAGACUA CAUCCCAA
600
UUGGGAUG CUGAUGAGGCCGUUAGGCCGAA AGUCUUUA
10019


3759
GACUACAUC CCAAUCAA
601
UUGAUUGG CUGAUGAGGCCGUUAGGCCGAA AUGUAGUC
10020


3765
AUCCCAAUC AAUGCCAU
602
AUGGCAUU CUGAUGAGGCCGUUAGGCCGAA AUUGGGAU
10021


3774
AAUGCCAUA CUGACAGG
603
CCUGUCAG CUGAUGAGGCCGUUAGGCCGAA AUGGCAUU
10022


3787
CAGGAAAUA CUGGGUUU
604
AAACCCAC CUGAUGAGGCCGUUAGGCCGAA AUUUCCUG
10023


3794
UAGUGGGUU UACAUACU
605
AGUAUGUA CUGAUGAGGCCGUUAGGCCGAA ACCCACUA
10024


3795
AGUGGGUUU ACAUACUC
606
GAGUAUGU CUGAUGAGGCCGUUAGGCCGAA AACCCACU
10025


3796
GUGGGUUUA CAUACUCA
607
UGAGUAUG CUGAUGAGGCCGUUAGGCCGAA AAACCCAC
10026


3800
GUUUACAUA CUCAACUC
608
GAGUUGAG CUGAUGAGGCCGUUAGGCCGAA AUGUAAAC
10027


3803
UACAUACUC AACUCCUG
609
CAGGAGUU CUGAUGAGGCCGUUAGGCCGAA AGUAUGUA
10028


3808
ACUCAACUC CUGCCUUC
610
GAAGGCAG CUGAUGAGGCCGUUAGGCCGAA AGUUCAGU
10029


3815
UCCUGCCUU CUCUGAGG
611
CCUCAGAG CUGAUGAGGCCGUUAGGCCGAA AGGCAGGA
10030


3816
CCUGCCUUC UCUGAGGA
612
UCCUCAGA CUGAUGAGGCCGUUAGGCCGAA AAGGCAGG
10031


3818
UGCCUUCUC UGAGGACU
613
AGUCCUCA CUGAUGAGGCCGUUAGGCCGAA AGAAGGCA
10032


3827
UGAGGACUU CUUCAAGG
614
CCUUGAAG CUGAUGAGGCCGUUAGGCCGAA AGUCCUCA
10033


3828
GAGGACUUC UUCAAGGA
615
UCCUUGAA CUGAUGAGGCCGUUAGGCCGAA AAGUCCUC
10034


3830
GGACUUCUU CAAGGAAA
616
UUUCCUUG CUGAUGAGGCCGUUAGGCCGAA AGAAGUCC
10035


3831
GACUUCUUC AAGGAAAG
617
CUUUCCUU CUGAUGAGGCCGUUAGGCCGAA AAGAAGUC
10036


3841
AGGAAAGUA UUUCAGCU
618
AGCUGAAA CUGAUGAGGCCGUUAGGCCGAA ACUUUCCU
10037


3843
GAAAGUAUU UCAGCUCC
619
GGAGCUGA CUGAUGAGGCCGUUAGGCCGAA AUACUUUC
10038


3844
AAAGUAUUU CAGCUCCG
620
CGGAGCUG CUGAUGAGGCCGUUAGGCCGAA AAUACUUU
10039


3845
AAGUAUUUC AGCUCCGA
621
UCGGAGCU CUGAUGAGGCCGUUAGGCCGAA AAAUACUU
10040


3850
UUUCAGCUC CGAAGUUU
622
AAACUUCG CUGAUGAGGCCGUUAGGCCGAA AGCUGAAA
10041


3857
UCCGAAGUU UAAUUCAG
623
CUGAAUUA CUGAUGAGGCCGUUAGGCCGAA ACUUCGGA
10042


3858
CCGAAGUUU AAUUCAGG
624
CCUGAAUU CUGAUGAGGCCGUUAGGCCGAA AACUUCGG
10043


3859
CGAAGUUUA AUUCAGGA
625
UCCUGAAU CUGAUGAGGCCGUUAGGCCGAA AAACUUCG
10044


3862
AGUUUAAUU CAGGAAGC
626
GCUUCCUG CUGAUGAGGCCGUUAGGCCGAA AUUAAACU
10045


3863
GUUUAAUUC AGGAAGCU
627
AGCUUCCU CUGAUGAGGCCGUUAGGCCGAA AAUUAAAC
10046


3872
AGGAAGCUC UGAUGAUG
628
CAUCAUCA CUGAUGAGGCCGUUAGGCCGAA AGCUUCCU
10047


3882
GAUGAUGUC AGAUAUGU
629
ACAUAUCU CUGAUGAGGCCGUUAGGCCGAA ACAUCAUC
10048


3887
UGUCAGAUA UGUAAAUG
630
CAUUUACA CUGAUGAGGCCGUUAGGCCGAA AUCUGACA
10049


3891
AGAUAUGUA AAUGCUUU
631
AAAGCAUU CUGAUGAGGCCGUUAGGCCGAA ACAUAUCU
10050


3898
UAAAUGCUU UCAAGUUC
632
GAACUUGA CUGAUGAGGCCGUUAGGCCGAA AGCAUUUA
10051


3899
AAAUGCUUU CAAGUUCA
633
UGAACUUG CUGAUGAGGCCGUUAGGCCGAA AAGCAUUU
10052


3900
AAUGCUUUC AAGUUCAU
634
AUGAACUU CUGAUGAGGCCGUUAGGCCGAA AAAGCAUU
10053


3905
UUUCAAGUU CAUGAGCC
635
GGCUCAUG CUGAUGAGGCCGUUAGGCCGAA ACUUGAAA
10054


3906
UUCAAGUUC AUGAGCCU
636
AGGCUCAU CUGAUGAGGCCGUUAGGCCGAA AACUUGAA
10055


3924
GAAAGAAUC AAAACCUU
637
AAGGUUUU CUGAUGAGGCCGUUAGGCCGAA AUUCUUUC
10056


3932
CAAAACCUU UGAAGAAC
638
GUUCUUCA CUGAUGAGGCCGUUAGGCCGAA AGGUUUUG
10057


3933
AAAACCUUU GAAGAACU
639
AGUUCUUC CUGAUGAGGCCGUUAGGCCGAA AAGGUUUU
10058


3942
GAAGAACUU UUACCGAA
640
UUCGGUAA CUGAUGAGGCCGUUAGGCCGAA AGUUCUUC
10059


3943
AAGAACUUU UACCGAAU
641
AUUCGGUA CUGAUGAGGCCGUUAGGCCGAA AAGUUCUU
10060


3944
AGAACUUUU ACCGAAUC
642
CAUUCGGU CUGAUGAGGCCGUUAGGCCGAA AAAGUUCU
10061


3945
GAACUUUUA CCGAAUGC
643
GCAUUCGG CUGAUGAGGCCGUUAGGCCGAA AAAAGUUC
10062


3959
UGCCACCUC CAUGUUUG
644
CAAACAUG CUGAUGAGGCCGUUAGGCCGAA AGGUGGCA
10063


3965
CUCCAUGUU UGAUGACU
645
AGUCAUCA CUGAUGAGGCCGUUAGGCCGAA ACAUGGAG
10064


3966
UCCAUGUUU GAUGACUA
646
UAGUCAUC CUGAUGAGGCCGUUAGGCCGAA AACAUGGA
10065


3974
UGAUGACUA CCAGGGCG
647
CGCCCUGG CUGAUGAGGCCGUUAGGCCGAA AGUCAUCA
10066


3994
GCAGCACUC UGUUGGCC
648
GGCCAACA CUGAUGAGGCCGUUAGGCCGAA AGUGCUGC
10067


3998
CACUCUGUU GGCCUCUC
649
GAGAGGCC CUGAUGAGGCCGUUAGGCCGAA ACAGAGUG
10068


4004
GUUGGCCUC UCCCAUGC
650
GCAUGGGA CUGAUGAGGCCGUUAGGCCGAA AGGCCAAC
10069


4006
UGGCCUCUC CCAUGCUG
651
CAGCAUGG CUGAUGAGGCCGUUAGGCCGAA AGAGGCCA
10070


4022
GAAGCGCUU CACCUGGA
652
UCCAGGUG CUGAUGAGGCCGUUAGGCCGAA AGCGCUUC
10071


4023
AAGCGCUUC ACCUGGAC
653
GUCCAGGU CUGAUGAGGCCGUUAGGCCGAA AAGCGCUU
10072


4052
CAAGGCCUC GCUCAAGA
654
UCUUGAGC CUGAUGAGGCCGUUAGGCCGAA AGGCCUUG
10073


4056
GCCUCGCUC AAGAUUGA
655
UCAAUCUU CUGAUGAGGCCGUUAGGCCGAA AGCGAGGC
10074


4062
CUCAAGAUU GACUUGAG
656
CUCAAGUC CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
10075


4067
GAUUGACUU GAGAGUAA
657
UUACUCUC CUGAUGAGGCCGUUAGGCCGAA AGUCAAUC
10076


4074
UUGAGAGUA ACCAGUAA
658
UUACUGGU CUGAUGAGGCCGUUAGGCCGAA ACUCUCAA
10077


4081
UAACCAGUA AAAGUAAG
659
CUUACUUU CUGAUGAGGCCGUUAGGCCGAA ACUGGUUA
10078


4087
GUAAAAGUA AGGAGUCG
660
CGACUCCU CUGAUGAGGCCGUUAGGCCGAA ACUUUUAC
10079


4094
UAAGGAGUC GGGGCUGU
661
ACAGCCCC CUGAUGAGGCCGUUAGGCCGAA ACUCCUUA
10080


4103
GGGGCUGUC UGAUGUCA
662
UGACAUCA CUGAUGAGGCCGUUAGGCCGAA ACAGCCCC
10081


4110
UCUGAUGUC AGCAGGCC
663
GGCCUGCU CUGAUGAGGCCGUUAGGCCGAA ACAUCAGA
10082


4123
GGCCCAGUU UCUGCCAU
664
AUGGCAGA CUGAUGAGGCCGUUAGGCCGAA ACUGGGCC
10083


4124
GCCCAGUUU CUGCCAUU
665
AAUGGCAG CUGAUGAGGCCGUUAGGCCGAA AACUGGGC
10084


4125
CCCAGUUUC UGCCAUUC
666
GAAUGGCA CUGAUGAGGCCGUUAGGCCGAA AAACUGGG
10085


4132
UCUGCCAUU CCAGCUGU
667
ACAGCUGG CUGAUGAGGCCGUUAGGCCGAA AUGGCAGA
10086


4133
CUGCCAUUC CAGCUGUG
668
CACAGCUG CUGAUGAGGCCGUUAGGCCGAA AAUGGCAG
10087


4149
GGGCACGUC AGCGAAGG
669
CCUUCGCU CUGAUGAGGCCGUUAGGCCGAA ACGUGCCC
10088


4169
GCGCAGGUU CACCUACG
670
CGUAGGUG CUGAUGAGGCCGUUAGGCCGAA ACCUGCGC
10089


4170
CGCAGGUUC ACCUACGA
671
UCGUAGGU CUGAUGAGGCCGUUAGGCCGAA AACCUGCG
10090


4175
GUUCACCUA CGACCACG
672
CGUGGUCG CUGAUGAGGCCGUUAGGCCGAA AGGUGAAC
10091


4203
AGGAAAAUC GCGUGCUG
673
CAGCACGC CUGAUGAGGCCGUUAGGCCGAA AUUUUCCU
10092


4214
GUGCUGCUC CCCGCCCC
674
GGGGCGGG CUGAUGAGGCCGUUAGGCCGAA AGCAGCAC
10093


4229
CCCAGACUA CAACUCGG
675
CCGAGUUG CUGAUGAGGCCGUUAGGCCGAA AGUCUGGG
10094


4235
CUACAACUC GGUGGUCC
676
GGACCACC CUGAUGAGGCCGUUAGGCCGAA AGUUGUAG
10095


4242
UCGGUGGUC CUGUACUC
677
GAGUACAG CUGAUGAGGCCGUUAGGCCGAA ACCACCGA
10096


4247
GGUCCUGUA CUCCACCC
678
GGGUGGAG CUGAUGAGGCCGUUAGGCCGAA ACAGGACC
10097


4250
CCUGUACUC CACCCCAC
679
GUGGGGUG CUGAUGAGGCCGUUAGGCCGAA AGUACAGG
10098


4263
CCACCCAUC UAGAGUUU
680
AAACUCUA CUGAUGAGGCCGUUAGGCCGAA AUGGGUGG
10099


4265
ACCCAUCUA GAGUUUGA
681
UCAAACUC CUGAUGAGGCCGUUAGGCCGAA AGAUGGGU
10100


4270
UCUAGAGUU UGACACGA
682
UCGUGUCA CUGAUGAGGCCGUUAGGCCGAA ACUCUAGA
10101


4271
CUAGAGUUU GACACGAA
683
UUCGUGUC CUGAUGAGGCCGUUAGGCCGAA AACUCUAG
10102


4284
CGAAGCCUU AUUUCUAG
684
CUAGAAAU CUGAUGAGGCCGUUAGGCCGAA AGGCUUCG
10103


4285
GAAGCCUUA UUUCUAGA
685
UCUAGAAA CUGAUGAGGCCGUUAGGCCGAA AAGGCUUC
10104


4287
AGCCUUAUU UCUAGAAG
686
CUUCUAGA CUGAUGAGGCCGUUAGGCCGAA AUAAGGCU
10105


4288
GCCUUAUUU CUAGAAGC
687
GCUUCUAG CUGAUGAGGCCGUUAGGCCGAA AAUAAGGC
10106


4289
CCUUAUUUC UAGAAGCA
688
UGCUUCUA CUGAUGAGGCCGUUAGGCCGAA AAAUAAGG
10107


4291
UUAUUUCUA GAAGCACA
689
UGUGCUUC CUGAUGAGGCCGUUAGGCCGAA AGAAAUAA
10108


4305
ACAUGUGUA UUUAUACC
690
GGUAUAAA CUGAUGAGGCCGUUAGGCCGAA ACACAUGU
10109


4307
AUGUGUAUU UAUACCCC
691
GGGGUAUA CUGAUGAGGCCGUUAGGCCGAA AUACACAU
10110


4308
UGUGUAUUU AUACCCCC
692
GGGGGUAU CUGAUGAGGCCGUUAGGCCGAA AAUACACA
10111


4309
GUGUAUUUA UACCCCCA
693
UGGGGGUA CUGAUGAGGCCGUUAGGCCGAA AAAUACAC
10112


4311
GUAUUUAUA CCCCCAGG
694
CCUGGGGG CUGAUGAGGCCGUUAGGCCGAA AUAAAUAC
10113


4325
AGGAAACUA GCUUUUGC
695
GCAAAAGC CUGAUGAGGCCGUUAGGCCGAA AGUUUCCU
10114


4329
AACUAGCUU UUGCCAGU
696
ACUGGCAA CUGAUGAGGCCGUUAGGCCGAA AGCUAGUU
10115


4330
ACUAGCUUU UGCCAGUA
697
UACUGGCA CUGAUGAGGCCGUUAGGCCGAA AAGCUAGU
10116


4331
CUAGCUUUU GCCAGUAU
698
AUACUGGC CUGAUGAGGCCGUUAGGCCGAA AAAGCUAG
10117


4338
UUGCCAGUA UUAUGCAU
699
AUGCAUAA CUGAUGAGGCCGUUAGGCCGAA ACUGGCAA
10118


4340
GCCAGUAUU AUGCAUAU
700
AUAUGCAU CUGAUGAGGCCGUUAGGCCGAA AUACUGGC
10119


4341
CCAGUAUUA UGCAUAUA
701
UAUAUGCA CUGAUGAGGCCGUUAGGCCGAA AAUACUGG
10120


4347
UUAUGCAUA UAUAAGUU
702
AACUUAUA CUGAUGAGGCCGUUAGGCCGAA AUGCAUAA
10121


4349
AUGCAUAUA UAACUUUA
703
UAAACUUA CUGAUGAGGCCGUUAGGCCGAA AUAUGCAU
10122


4351
GCAUAUAUA AGUUUACA
704
UGUAAACU CUGAUGAGGCCGUUAGGCCGAA AUAUAUGC
10123


4355
AUAUAAGUU UACACCUU
705
AAGGUGUA CUGAUGAGGCCGUUAGGCCGAA ACUUAUAU
10124


4356
UAUAAGUUU ACACCUUU
706
AAAGGUGU CUGAUGAGGCCGUUAGGCCGAA AACUUAUA
10125


4357
AUAAGUUUA CACCUUUA
707
UAAAGGUG CUGAUGAGGCCGUUAGGCCGAA AAACUUAU
10126


4363
UUACACCUU UAUCUUUC
708
GAAAGAUA CUGAUGAGGCCGUUAGGCCGAA AGGUGUAA
10127


4364
UACACCUUU AUCUUUCC
709
GGAAAGAU CUGAUGAGGCCGUUAGGCCGAA AAGGUGUA
10128


4365
ACACCUUUA UCUUUCCA
710
UGGAAAGA CUGAUGAGGCCGUUAGGCCGAA AAAGGUGU
10129


4367
ACCUUUAUC UUUCCAUG
711
CAUGGAAA CUGAUGAGGCCGUUAGGCCGAA AUAAAGGU
10130


4369
CUUUAUCUU UCCAUGGG
712
CCCAUGGA CUGAUGAGGCCGUUAGGCCGAA AGAUAAAG
10131


4370
UUUAUCUUU CCAUGGGA
713
UCCCAUGG CUGAUGAGGCCGUUAGGCCGAA AAGAUAAA
10132


4371
UUAUCUUUC CAUGGGAG
714
CUCCCAUG CUGAUGAGGCCGUUAGGCCGAA AAAGAUAA
10133


4389
CAGCUGCUU UUUGUGAU
715
AUCACAAA CUGAUGAGGCCGUUAGGCCGAA AGCAGCUG
10134


4390
AGCUGCUUU UUGUGAUU
716
AAUCACAA CUGAUGAGGCCGUUAGGCCGAA AAGCAGCU
10135


4391
GCUGCUUUU UGUGAUUU
717
AAAUCACA CUGAUGAGGCCGUUAGGCCGAA AAAGCAGC
10136


4392
CUGCUUUUU GUGAUUUU
718
AAAAUCAC CUGAUGAGGCCGUUAGGCCGAA AAAAGCAG
10137


4398
UUUGUGAUU UUUUUAAU
719
AUUAAAAA CUGAUGAGGCCGUUAGGCCGAA AUCACAAA
10138


4399
UUGUGAUUU UUUUAAUA
720
UAUUAAAA CUGAUGAGGCCGUUAGGCCGAA AAUCACAA
10139


4400
UGUGAUUUU UUUAAUAG
721
CUAUUAAA CUGAUGAGGCCGUUAGGCCGAA AAAUCACA
10140


4401
GUGAUUUUU UUAAUAGU
722
ACUAUUAA CUGAUGAGGCCGUUAGGCCGAA AAAAUCAC
10141


4402
UGAUUUUUU UAAUAGUG
723
CACUAUUA CUGAUGAGGCCGUUAGGCCGAA AAAAAUCA
10142


4403
GAUUUUUUU AAUAGUGC
724
GCACUAUU CUGAUGAGGCCGUUAGGCCGAA AAAAAAUC
10143


4404
AUUUUUUUA AUAGUGCU
725
AGCACUAU CUGAUGAGGCCGUUAGGCCGAA AAAAAAAU
10144


4407
UUUUUAAUA GUGCUUUU
726
AAAAGCAC CUGAUGAGGCCGUUAGGCCGAA AUUAAAAA
10145


4413
AUAGUGCUU UUUUUUUU
727
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AGCACUAU
10146


4414
UAGUGCUUU UUUUUUUU
728
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAGCACUA
10147


4415
AGUGCUUUU UUUUUUUG
729
CAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAGCACU
10148


4416
GUGCUUUUU UUUUUUGA
730
UCAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAGCAC
10149


4417
UGCUUUUUU UUUUUGAC
731
GUCAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAGCA
10150


4418
GCUUUUUUU UUUUGACU
732
AGUCAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAGC
10151


4419
CUUUUUUUU UUUGACUA
733
UAGUCAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAG
10152


4420
UUUUUUUUU UUGACUAA
734
UUAGUCAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10153


4421
UUUUUUUUU UGACUAAC
735
GUUAGUCA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10154


4422
UUUUUUUUU GACUAACA
736
UGUUAGUC CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10155


4427
UUUUGACUA ACAAGAAU
737
AUUCUUGU CUGAUGAGGCCGUUAGGCCGAA AGUCAAAA
10156


4438
AAGAAUGUA ACUCCAGA
738
UCUGGAGU CUGAUGAGGCCGUUAGGCCGAA ACAUUCUU
10157


4442
AUGUAACUC CAGAUAGA
739
UCUAUCUG CUGAUGAGGCCGUUAGGCCGAA AGUUACAU
10158


4448
CUCCAGAUA GAGAAAUA
740
UAUUUCUC CUGAUGAGGCCGUUAGGCCGAA AUCUGGAG
10159


4456
AGAGAAAUA GUGACAAG
741
CUUGUCAC CUGAUGAGGCCGUUAGGCCGAA AUUUCUCU
10160


4476
AGAACACUA CUGCUAAA
742
UUUAGCAG CUGAUGAGGCCGUUAGGCCGAA AGUGUUCU
10161


4482
CUACUGCUA AAUCCUCA
743
UGAGGAUU CUGAUGAGGCCGUUAGGCCGAA AGCAGUAG
10162


4486
UGCUAAAUC CUCAUGUU
744
AACAUGAG CUGAUGAGGCCGUUAGGCCGAA AUUUAGCA
10163


4489
UAAAUCCUC AUGUUACU
745
AGUAACAU CUGAUGAGGCCGUUAGGCCGAA AGGAUUUA
10164


4494
CCUCAUGUU ACUCAGUG
746
CACUGAGU CUGAUGAGGCCGUUAGGCCGAA ACAUGAGG
10165


4495
CUCAUGUUA CUCAGUGU
747
ACACUGAG CUGAUGAGGCCGUUAGGCCGAA AACAUGAG
10166


4498
AUGUUACUC AGUGUUAG
748
CUAACACU CUGAUGAGGCCGUUAGGCCGAA AGUAACAU
10167


4504
CUCAGUGUU AGAGAAAU
749
AUUUCUCU CUGAUGAGGCCGUUAGGCCGAA ACACUGAG
10168


4505
UCAGUGUUA GAGAAAUC
750
GAUUUCUC CUGAUGAGGCCGUUAGGCCGAA AACACUGA
10169


4513
AGAGAAAUC CUUCCUAA
751
UUAGGAAG CUGAUGAGGCCGUUAGGCCGAA AUUUCUCU
10170


4516
GAAAUCCUU CCUAAACC
752
GGUUUAGG CUGAUGAGGCCGUUAGGCCGAA AGGAUUUC
10171


4517
AAAUCCUUC CUAAACCC
753
GGGUUUAG CUGAUGAGGCCGUUAGGCCGAA AAGGAUUU
10172


4520
UCCUUCCUA AACCCAAU
754
AUUGGGUU CUGAUGAGGCCGUUAGGCCGAA AGGAAGGA
10173


4533
CAAUGACUU CCCUGCUC
755
GAGCAGGG CUGAUGAGGCCGUUAGGCCGAA AGUCAUUG
10174


4534
AAUGACUUC CCUGCUCC
756
GGAGCAGG CUGAUGAGGCCGUUAGGCCGAA AAGUCAUU
10175


4541
UCCCUGCUC CAACCCCC
757
GGGGGUUG CUGAUGAGGCCGUUAGGCCGAA AGCAGGGA
10176


4557
CGCCACCUC AGGGCACG
758
CGUGCCCU CUGAUGAGGCCGUUAGGCCGAA AGGUGGCG
10177


4576
GGACCAGUU UGAUUGAG
759
CUCAAUCA CUGAUGAGGCCGUUAGGCCGAA ACUGGUCC
10178


4577
GACCAGUUU GAUUGAGG
760
CCUCAAUC CUGAUGAGGCCGUUAGGCCGAA AACUGGUC
10179


4581
AGUUUGAUU GAGGAGCU
761
AGCUCCUC CUGAUGAGGCCGUUAGGCCGAA AUCAAACU
10180


4598
GCACUGAUC ACCCAAUG
762
CAUUGGGU CUGAUGAGGCCGUUAGGCCGAA AUCAGUGC
10181


4610
CAAUGCAUC ACGUACCC
763
GGGUACGU CUGAUGAGGCCGUUAGGCCGAA AUGCAUUG
10182


4615
CAUCACGUA CCCCACUG
764
CAGUGGGG CUGAUGAGGCCGUUAGGCCGAA ACGUGAUG
10183


4664
AAGCCCGUU AGCCCCAG
765
CUGGGGCU CUGAUGAGGCCGUUAGGCCGAA ACGGGCUU
10184


4665
AGCCCGUUA GCCCCAGG
766
CCUGGGGC CUGAUGAGGCCGUUAGGCCGAA AACGGGCU
10185


4678
CAGGGGAUC ACUGGCUG
767
CAGCCAGU CUGAUGAGGCCGUUAGGCCGAA AUCCCCUG
10186


4700
AGCAACAUC UCGGGAGU
768
ACUCCCGA CUGAUGAGGCCGUUAGGCCGAA AUGUUGCU
10187


4702
CAACAUCUC GGGAGUCC
769
GGACUCCC CUGAUGAGGCCGUUAGGCCGAA AGAUGUUG
10188


4709
UCGGGAGUC CUCUAGCA
770
UGCUAGAG CUGAUGAGGCCGUUAGGCCGAA ACUCCCGA
10189


4712
GGAGUCCUC UAGCAGGC
771
GCCUGCUA CUGAUGAGGCCGUUAGGCCGAA AGGACUCC
10190


4714
AGUCCUCUA GCAGGCCU
772
AGGCCUGC CUGAUGAGGCCGUUAGGCCGAA AGAGGACU
10191


4723
GCAGGCCUA AGACAUGU
773
ACAUGUCU CUGAUGAGGCCGUUAGGCCGAA AGGCCUGC
10192


4802
GAAAGAAUU UGAGACGC
774
GCGUCUCA CUGAUGAGGCCGUUAGGCCGAA AUUCUUUC
10193


4803
AAAGAAUUU GAGACGCA
775
UGCGUCUC CUGAUGAGGCCGUUAGGCCGAA AAUUCUUU
10194


4840
ACGGGGCUC AGCAAUGC
776
GCAUUGCU CUGAUGAGGCCGUUAGGCCGAA AGCCCCGU
10195


4852
AAUGCCAUU UCAGUGGC
777
GCCACUGA CUGAUGAGGCCGUUAGGCCGAA AUGGCAUU
10196


4853
AUGCCAUUU CAGUGGCU
778
AGCCACUG CUGAUGAGGCCGUUAGGCCGAA AAUGGCAU
10197


4854
UGCCAUUUC AGUGGCUU
779
AAGCCACU CUGAUGAGGCCGUUAGGCCGAA AAAUGGCA
10198


4862
CAGUGGCUU CCCAGCUC
780
GAGCUGGG CUGAUGAGGCCGUUAGGCCGAA AGCCACUG
10199


4863
AGUGGCUUC CCAGCUCU
781
AGAGCUGG CUGAUGAGGCCGUUAGGCCGAA AAGCCACU
10200


4870
UCCCAGCUC UGACCCUU
782
AAGGGUCA CUGAUGAGGCCGUUAGGCCGAA AGCUGGGA
10201


4878
CUGACCCUU CUACAUUU
783
AAAUGUAG CUGAUGAGGCCGUUAGGCCGAA AGGGUCAG
10202


4879
UGACCCUUC UACAUUUG
784
CAAAUGUA CUGAUGAGGCCGUUAGGCCGAA AAGGGUCA
10203


4881
ACCCUUCUA CAUUUGAG
785
CUCAAAUG CUGAUGAGGCCGUUAGGCCGAA AGAAGGGU
10204


4885
UUCUACAUU UGAGGGCC
786
GGCCCUCA CUGAUGAGGCCGUUAGGCCGAA AUGUAGAA
10205


4886
UCUACAUUU GAGGGCCC
787
GGGCCCUC CUGAUGAGGCCGUUAGGCCGAA AAUGUAGA
10206


4929
GGGGACAUU UUCUGGAU
788
AUCCAGAA CUGAUGAGGCCGUUAGGCCGAA AUGUCCCC
10207


4930
GGGACAUUU UCUGGAUU
789
AAUCCAGA CUGAUGAGGCCGUUAGGCCGAA AAUGUCCC
10208


4931
GGACAUUUU CUGGAUUC
790
GAAUCCAG CUGAUGAGGCCGUUAGGCCGAA AAAUGUCC
10209


4932
GACAUUUUC UGGAUUCU
791
AGAAUCCA CUGAUGAGGCCGUUAGGCCGAA AAAAUGUC
10210


4938
UUCUGGAUU CUGGGAGG
792
CCUCCCAG CUGAUGAGGCCGUUAGGCCGAA AUCCAGAA
10211


4939
UCUGGAUUC UGGGAGGC
793
GCCUCCCA CUGAUGAGGCCGUUAGGCCGAA AAUCCAGA
10212


4963
GGACAAAUA UCUUUUUU
794
AAAAAAGA CUGAUGAGGCCGUUAGGCCGAA AUUUGUCC
10213


4965
ACAAAUAUC UUUUUUGG
795
CCAAAAAA CUGAUGAGGCCGUUAGGCCGAA AUAUUUGU
10214


4967
AAAUAUCUU UUUUGGAA
796
UUCCAAAA CUGAUGAGGCCGUUAGGCCGAA AGAUAUUU
10215


4968
AAUAUCUUU UUUGGAAC
797
GUUCCAAA CUGAUGAGGCCGUUAGGCCGAA AAGAUAUU
10216


4969
AUAUCUUUU UUGGAACU
798
AGUUCCAA CUGAUGAGGCCGUUAGGCCGAA AAAGAUAU
10217


4970
UAUCUUUUU UGGAACUA
799
UAGUUCCA CUGAUGAGGCCGUUAGGCCGAA AAAAGAUA
10218


4971
AUCUUUUUU GGAACUAA
800
UUAGUUCC CUGAUGAGGCCGUUAGGCCGAA AAAAAGAU
10219


4978
UUGGAACUA AAGCAAAU
801
AUUUGCUU CUGAUGAGGCCGUUAGGCCGAA AGUUCCAA
10220


4987
AAGCAAAUU UUAGACCU
802
AGGUCUAA CUGAUGAGGCCGUUAGGCCGAA AUUUGCUU
10221


4988
AGCAAAUUU UAGACCUU
803
AAGGUCUA CUGAUGAGGCCGUUAGGCCGAA AAUUUGCU
10222


4989
GCAAAUUUU AGACCUUU
804
AAAGGUCU CUGAUGAGGCCGUUAGGCCGAA AAAUUUGC
10223


4990
CAAAUUUUA GACCUUUA
805
UAAAGGUC CUGAUGAGGCCGUUAGGCCGAA AAAAUUUG
10224


4996
UUAGACCUU UACCUAUG
806
CAUAGGUA CUGAUGAGGCCGUUAGGCCGAA AGGUCUAA
10225


4997
UAGACCUUU ACCUAUGG
807
CCAUAGGU CUGAUGAGGCCGUUAGGCCGAA AAGGUCUA
10226


4998
AGACCUUUA CCUAUGGA
808
UCCAUAGG CUGAUGAGGCCGUUAGGCCGAA AAAGGUCU
10227


5002
CUUUACCUA UGGAAGUG
809
CACUUCCA CUGAUGAGGCCGUUAGGCCGAA AGGUAAAG
10228


5013
GAAGUGGUU CUAUGUCC
810
GGACAUAG CUGAUGAGGCCGUUAGGCCGAA ACCACUUC
10229


5014
AAGUGGUUC UAUGUCCA
811
UGGACAUA CUGAUGAGGCCGUUAGGCCGAA AACCACUU
10230


5016
GUGGUUCUA UGUCCAUU
812
AAUGGACA CUGAUGAGGCCGUUAGGCCGAA AGAACCAC
10231


5020
UUCUAUGUC CAUUCUCA
813
UGAGAAUG CUGAUGAGGCCGUUAGGCCGAA ACAUAGAA
10232


5024
AUGUCCAUU CUCAUUCG
814
CGAAUGAG CUGAUGAGGCCGUUAGGCCGAA AUGGACAU
10233


5025
UGUCCAUUC UCAUUCGU
815
ACGAAUGA CUGAUGAGGCCGUUAGGCCGAA AAUGGACA
10234


5027
UCCAUUCUC AUUCGUGG
816
CCACGAAU CUGAUGAGGCCGUUAGGCCGAA AGAAUGGA
10235


5030
AUUCUCAUU CGUGGCAU
817
AUGCCACG CUGAUGAGGCCGUUAGGCCGAA AUGAGAAU
10236


5031
UUCUCAUUC GUGGCAUG
818
CAUGCCAC CUGAUGAGGCCGUUAGGCCGAA AAUGAGAA
10237


5041
UGGCAUGUU UUGAUUUG
819
CAAAUCAA CUGAUGAGGCCGUUAGGCCGAA ACAUGCCA
10238


5042
GGCAUGUUU UGAUUUGU
820
ACAAAUCA CUGAUGAGGCCGUUAGGCCGAA AACAUGCC
10239


5043
GCAUGUUUU GAUUUGUA
821
UACAAAUC CUGAUGAGGCCGUUAGGCCGAA AAACAUGC
10240


5047
GUUUUGAUU UGUAGCAC
822
GUGCUACA CUGAUGAGGCCGUUAGGCCGAA AUCAAAAC
10241


5048
UUUUGAUUU GUAGCACU
823
AGUGCUAC CUGAUGAGGCCGUUAGGCCGAA AAUCAAAA
10242


5051
UGAUUUGUA GCACUGAG
824
CUCAGUGC CUGAUGAGGCCGUUAGGCCGAA ACAAAUCA
10243


5069
GUGGCACUC AACUCUGA
825
UCAGAGUU CUGAUGAGGCCGUUAGGCCGAA AGUGCCAC
10244


5074
ACUCAACUC UGAGCCCA
826
UGGGCUCA CUGAUGAGGCCGUUAGGCCGAA AGUUGAGU
10245


5084
GAGCCCAUA CUUUUGGC
827
GCCAAAAG CUGAUGAGGCCGUUAGGCCGAA AUGGGCUC
10246


5087
CCCAUACUU UUGGCUCC
828
GGAGCCAA CUGAUGAGGCCGUUAGGCCGAA AGUAUGGG
10247


5088
CCAUACUUU UGGCUCCU
829
AGGAGCCA CUGAUGAGGCCGUUAGGCCGAA AAGUAUGG
10248


5089
CAUACUUUU GGCUCCUC
830
GAGGAGCC CUGAUGAGGCCGUUAGGCCGAA AAAGUAUG
10249


5094
UUUUGGCUC CUCUAGUA
831
UACUAGAG CUGAUGAGGCCGUUAGGCCGAA AGCCAAAA
10250


5097
UGGCUCCUC UAGUAAGA
832
UCUUACUA CUGAUGAGGCCGUUAGGCCGAA AGGAGCCA
10251


5099
GCUCCUCUA GUAAGAUG
833
CAUCUUAC CUGAUGAGGCCGUUAGGCCGAA AGAGGAGC
10252


5102
CCUCUAGUA AGAUGCAC
834
GUGCAUCU CUGAUGAGGCCGUUAGGCCGAA ACUAGAGG
10253


5119
UGAAAACUU AGCCAGAG
835
CUCUGGCU CUGAUGAGGCCGUUAGGCCGAA AGUUUUCA
10254


5120
GAAAACUUA GCCAGAGU
836
ACUCUGGC CUGAUGAGGCCGUUAGGCCGAA AAGUUUUC
10255


5129
GCCAGAGUU AGGUUGUC
837
GACAACCU CUGAUGAGGCCGUUAGGCCGAA ACUCUGGC
10256


5130
CCAGAGUUA GGUUGUCU
838
AGACAACC CUGAUGAGGCCGUUAGGCCGAA AACUCUGG
10257


5134
AGUUAGGUU GUCUCCAG
839
CUGGAGAC CUGAUGAGGCCGUUAGGCCGAA ACCUAACU
10258


5137
UAGGUUGUC UCCAGGCC
840
GGCCUGGA CUGAUGAGGCCGUUAGGCCGAA ACAACCUA
10259


5139
GGUUGUCUC CAGGCCAU
841
AUGGCCUG CUGAUGAGGCCGUUAGGCCGAA AGACAACC
10260


5156
GAUGGCCUU ACACUGAA
842
UUCAGUGU CUGAUGAGGCCGUUAGGCCGAA AGGCCAUC
10261


5157
AUGGCCUUA CACUGAAA
843
UUUCAGUG CUGAUGAGGCCGUUAGGCCGAA AAGGCCAU
10262


5170
GAAAAUGUC ACAUUCUA
844
UAGAAUGU CUGAUGAGGCCGUUAGGCCGAA ACAUUUUC
10263


5175
UGUCACAUU CUAUUUUG
845
CAAAAUAG CUGAUGAGGCCGUUAGGCCGAA AUGUGACA
10264


5176
GUCACAUUC UAUUUUGG
846
CCAAAAUA CUGAUGAGGCCGUUAGGCCGAA AAUGUGAC
10265


5178
CACAUUCUA UUUUGGGU
847
ACCCAAAA CUGAUGAGGCCGUUAGGCCGAA AGAAUGUG
10266


5180
CAUUCUAUU UUGGGUAU
848
AUACCCAA CUGAUGAGGCCGUUAGGCCGAA AUAGAAUG
10267


5181
AUUCUAUUU UGGGUAUU
849
AAUACCCA CUGAUGAGGCCGUUAGGCCGAA AAUAGAAU
10268


5182
UUCUAUUUU GGGUAUUA
850
UAAUACCC CUGAUGAGGCCGUUAGGCCGAA AAAUAGAA
10269


5187
UUUUGGGUA UUAAUAUA
851
UAUAUUAA CUGAUGAGGCCGUUAGGCCGAA ACCCAAAA
10270


5189
UUGGGUAUU AAUAUAUA
852
UAUAUAUU CUGAUGAGGCCGUUAGGCCGAA AUACCCAA
10271


5190
UGGGUAUUA AUAUAUAG
853
CUAUAUAU CUGAUGAGGCCGUUAGGCCGAA AAUACCCA
10272


5193
GUAUUAAUA UAUAGUCC
854
GGACUAUA CUGAUGAGGCCGUUAGGCCGAA AUUAAUAC
10273


5195
AUUAAUAUA UAGUCCAG
855
CUGGACUA CUGAUGAGGCCGUUAGGCCGAA AUAUUAAU
10274


5197
UAAUAUAUA GUCCAGAC
856
GUCUGGAC CUGAUGAGGCCGUUAGGCCGAA AUAUAUUA
10275


5200
UAUAUAGUC CAGACACU
857
AGUGUCUG CUGAUGAGGCCGUUAGGCCGAA ACUAUAUA
10276


5209
CAGACACUU AACUCAAU
858
AUUGAGUU CUGAUGAGGCCGUUAGGCCGAA AGUGUCUG
10277


5210
AGACACUUA ACUCAAUU
859
AAUUGAGU CUGAUGAGGCCGUUAGGCCGAA AAGUGUCU
10278


5214
ACUUAACUC AAUUUCUU
860
AAGAAAUU CUGAUGAGGCCGUUAGGCCGAA AGUUAAGU
10279


5218
AACUCAAUU UCUUGGUA
861
UACCAAGA CUGAUGAGGCCGUUAGGCCGAA AUUGAGUU
10280


5219
ACUCAAUUU CUUGGUAU
862
AUACCAAG CUGAUGAGGCCGUUAGGCCGAA AAUUGAGU
10281


5220
CUCAAUUUC UUGGUAUU
863
AAUACCAA CUGAUGAGGCCGUUAGGCCGAA AAAUUGAG
10282


5222
CAAUUUCUU GGUAUUAU
864
AUAAUACC CUGAUGAGGCCGUUAGGCCGAA AGAAAUUG
10283


5226
UUCUUGGUA UUAUUCUG
865
CAGAAUAA CUGAUGAGGCCGUUAGGCCGAA ACCAAGAA
10284


5228
CUUGGUAUU AUUCUGUU
866
AACAGAAU CUGAUGAGGCCGUUAGGCCGAA AUACCAAG
10285


5229
UUGGUAUUA UUCUGUUU
867
AAACAGAA CUGAUGAGGCCGUUAGGCCGAA AAUACCAA
10286


5231
GGUAUUAUU CUGUUUUG
868
CAAAACAG CUGAUGAGGCCGUUAGGCCGAA AUAAUACC
10287


5232
GUAUUAUUC UGUUUUGC
869
GCAAAACA CUGAUGAGGCCGUUAGGCCGAA AAUAAUAC
10288


5236
UAUUCUGUU UUGCACAG
870
CUGUGCAA CUGAUGAGGCCGUUAGGCCGAA ACAGAAUA
10289


5237
AUUCUGUUU UGCACAGU
871
ACUGUGCA CUGAUGAGGCCGUUAGGCCGAA AACAGAAU
10290


5238
UUCUGUUUU GCACAGUU
872
AACUGUGC CUGAUGAGGCCGUUAGGCCGAA AAACAGAA
10291


5246
UGCACAGUU AGUUGUGA
873
UCACAACU CUGAUGAGGCCGUUAGGCCGAA ACUGUGCA
10292


5247
GCACAGUUA GUUGUGAA
874
UUCACAAC CUGAUGAGGCCGUUAGGCCGAA AACUGUGC
10293


5250
CAGUUAGUU GUGAAAGA
875
UCUUUCAC CUGAUGAGGCCGUUAGGCCGAA ACUAACUG
10294


5284
AAUGCAGUC CUGAGGAG
876
CUCCUCAG CUGAUGAGGCCGUUAGGCCGAA ACUGCAUU
10295


5296
AGGAGAGUU UUCUCCAU
877
AUGGAGAA CUGAUGAGGCCGUUAGGCCGAA ACUCUCCU
10296


5297
GGAGAGUUU UCUCCAUA
878
UAUGGAGA CUGAUGAGGCCGUUAGGCCGAA AACUCUCC
10297


5298
GAGAGUUUU CUCCAUAU
879
AUAUGGAG CUGAUGAGGCCGUUAGGCCGAA AAACUCUC
10298


5299
AGAGUUUUC UCCAUAUC
880
GAUAUGGA CUGAUGAGGCCGUUAGGCCGAA AAAACUCU
10299


5301
AGUUUUCUC CAUAUCAA
881
UUGAUAUG CUGAUGAGGCCGUUAGGCCGAA AGAAAACU
10300


5305
UUCUCCAUA UCAAAACG
882
CGUUUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGAGAA
10301


5307
CUCCAUAUC AAAACGAG
883
CUCGUUUU CUGAUGAGGCCGUUAGGCCGAA AUAUGGAG
10302


5336
AAAAAGGUC AAUAAGGU
884
ACCUUAUU CUGAUGAGGCCGUUAGGCCGAA ACCUUUUU
10303


5340
AGGUCAAUA AGGUCAAG
885
CUUGACCU CUGAUGAGGCCGUUAGGCCGAA AUUGACCU
10304


5345
AAUAAGGUC AAGGGAAG
886
CUUCCCUU CUGAUGAGGCCGUUAGGCCGAA ACCUUAUU
10305


5361
GACCCCGUC UCUAUACC
887
GGUAUAGA CUGAUGAGGCCGUUAGGCCGAA ACGGGGUC
10306


5363
CCCCGUCUC UAUACCAA
888
UUGGUAUA CUGAUGAGGCCGUUAGGCCGAA AGACGGGG
10307


5365
CCGUCUCUA UACCAACC
889
GGUUGGUA CUGAUGAGGCCGUUAGGCCGAA AGAGACGG
10308


5367
GUCUCUAUA CCAACCAA
890
UUGGUUGG CUGAUGAGGCCGUUAGGCCGAA AUAGAGAC
10309


5382
AAACCAAUU CACCAACA
891
UGUUGGUG CUGAUGAGGCCGUUAGGCCGAA AUUGGUUU
10310


5383
AACCAAUUC ACCAACAC
892
GUGUUGGU CUGAUGAGGCCGUUAGGCCGAA AAUUGGUU
10311


5395
AACACAGUU GGGACCCA
893
UGGGUCCC CUGAUGAGGCCGUUAGGCCGAA ACUGUGUU
10312


5417
CAGGAAGUC AGUCACGU
894
ACGUGACU CUGAUGAGGCCGUUAGGCCGAA ACUUCCUG
10313


5421
AAGUCAGUC ACGUUUCC
895
GGAAACGU CUGAUGAGGCCGUUAGGCCGAA ACUGACUU
10314


5426
AGUCACGUU UCCUUUUC
896
GAAAAGGA CUGAUGAGGCCGUUAGGCCGAA ACGUGACU
10315


5427
GUCACGUUU CCUUUUCA
897
UGAAAAGG CUGAUGAGGCCGUUAGGCCGAA AACGUGAC
10316


5428
UCACGUUUC CUUUUCAU
898
AUGAAAAG CUGAUGAGGCCGUUAGGCCGAA AAACGUGA
10317


5431
CGUUUCCUU UUCAUUUA
899
UAAAUGAA CUGAUGAGGCCGUUAGGCCGAA AGGAAACG
10318


5432
GUUUCCUUU UCAUUUAA
900
UUAAAUGA CUGAUGAGGCCGUUAGGCCGAA AAGGAAAC
10319


5433
UUUCCUUUU CAUUUAAU
901
AUUAAAUG CUGAUGAGGCCGUUAGGCCGAA AAAGGAAA
10320


5434
UUCCUUUUC AUUUAAUG
902
CAUUAAAU CUGAUGAGGCCGUUAGGCCGAA AAAAGGAA
10321


5437
CUUUUCAUU UAAUGGGG
903
CCCCAUUA CUGAUGAGGCCGUUAGGCCGAA AUGAAAAG
10322


5438
UUUUCAUUU AAUGGGGA
904
UCCCCAUU CUGAUGAGGCCGUUAGGCCGAA AAUGAAAA
10323


5439
UUUCAUUUA AUGGGGAU
905
AUCCCCAU CUGAUGAGGCCGUUAGGCCGAA AAAUGAAA
10324


5448
AUGGGGAUU CCACUAUC
906
GAUAGUGG CUGAUGAGGCCGUUAGGCCGAA AUCCCCAU
10325


5449
UGGGGAUUC CACUAUCU
907
AGAUAGUG CUGAUGAGGCCGUUAGGCCGAA AAUCCCCA
10326


5454
AUUCCACUA UCUCACAC
908
GUGUGAGA CUGAUGAGGCCGUUAGGCCGAA AGUGGAAU
10327


5456
UCCACUAUC UCACACUA
909
UAGUGUGA CUGAUGAGGCCGUUAGGCCGAA AUAGUGGA
10328


5458
CACUAUCUC ACACUAAU
910
AUUAGUGU CUGAUGAGGCCGUUAGGCCGAA AGAUAGUG
10329


5464
CUCACACUA AUCUGAAA
911
UUUCAGAU CUGAUGAGGCCGUUAGGCCGAA AGUGUGAG
10330


5467
ACACUAAUC UGAAAGGA
912
UCCUUUCA CUGAUGAGGCCGUUAGGCCGAA AUUAGUGU
10331


5489
AAGAGCAUU AGCUGGCG
913
CGCCAGCU CUGAUGAGGCCGUUAGGCCGAA AUGCUCUU
10332


5490
AGAGCAUUA GCUGGCGC
914
GCGCCAGC CUGAUGAGGCCGUUAGGCCGAA AAUGCUCU
10333


5501
UGGCGCAUA UUAAGCAC
915
GUGCUUAA CUGAUGAGGCCGUUAGGCCGAA AUGCGCCA
10334


5503
GCGCAUAUU AAGCACUU
916
AAGUGCUU CUGAUGAGGCCGUUAGGCCGAA AUAUGCGC
10335


5504
CGCAUAUUA AGCACUUU
917
AAAGUGCU CUGAUGAGGCCGUUAGGCCGAA AAUAUGCG
10336


5511
UAAGCACUU UAAGCUCC
918
GGAGCUUA CUGAUGAGGCCGUUAGGCCGAA AGUGCUUA
10337


5512
AAGCACUUU AAGCUCCU
919
AGGAGCUU CUGAUGAGGCCGUUAGGCCGAA AAGUGCUU
10338


5513
AGCACUUUA AGCUCCUU
920
AAGGAGCU CUGAUGAGGCCGUUAGGCCGAA AAAGUGCU
10339


5518
UUUAAGCUC CUUGAGUA
921
UACUCAAG CUGAUGAGGCCGUUAGGCCGAA AGCUUAAA
10340


5521
AAGCUCCUU GAGUAAAA
922
UUUUACUC CUGAUGAGGCCGUUAGGCCGAA AGGAGCUU
10341


5526
CCUUGAGUA AAAAGGUG
923
CACCUUUU CUGAUGAGGCCGUUAGGCCGAA ACUCAAGG
10342


5537
AAGGUGGUA UGUAAUUU
924
AAAUUACA CUGAUGAGGCCGUUAGGCCGAA ACCACCUU
10343


5541
UGGUAUGUA AUUUAUGC
925
GCAUAAAU CUGAUGAGGCCGUUAGGCCGAA ACAUACCA
10344


5544
UAUGUAAUU UAUGCAAG
926
CUUGCAUA CUGAUGAGGCCGUUAGGCCGAA AUUACAUA
10345


5545
AUGUAAUUU AUGCAAGG
927
CCUUGCAU CUGAUGAGGCCGUUAGGCCGAA AAUUACAU
10346


5546
UGUAAUUUA UGCAAGGU
928
ACCUUGCA CUGAUGAGGCCGUUAGGCCGAA AAAUUACA
10347


5555
UGCAAGGUA UUUCUCCA
929
UGGAGAAA CUGAUGAGGCCGUUAGGCCGAA ACCUUGCA
10348


5557
CAAGGUAUU UCUCCAGU
930
ACUGGAGA CUGAUGAGGCCGUUAGGCCGAA AUACCUUG
10349


5558
AAGGUAUUU CUCCAGUU
931
AACUGGAG CUGAUGAGGCCGUUAGGCCGAA AAUACCUU
10350


5559
AGGUAUUUC UCCAGUUG
932
CAACUGGA CUGAUGAGGCCGUUAGGCCGAA AAAUACCU
10351


5561
GUAUUUCUC CAGUUGGG
933
CCCAACUG CUGAUGAGGCCGUUAGGCCGAA AGAAAUAC
10352


5566
UCUCCAGUU GGGACUCA
934
UGAGUCCC CUGAUGAGGCCGUUAGGCCGAA ACUGGAGA
10353


5573
UUGGGACUC AGGAUAUU
935
AAUAUCCU CUGAUGAGGCCGUUAGGCCGAA AGUCCCAA
10354


5579
CUCAGGAUA UUAGUUAA
936
UUAACUAA CUGAUGAGGCCGUUAGGCCGAA AUCCUGAG
10355


5581
CAGGAUAUU AGUUAAUG
937
CAUUAACU CUGAUGAGGCCGUUAGGCCGAA AUAUCCUG
10356


5582
AGGAUAUUA GUUAAUGA
938
UCAUUAAC CUGAUGAGGCCGUUAGGCCGAA AAUAUCCU
10357


5585
AUAUUAGUU AAUGAGCC
939
GGCUCAUU CUGAUGAGGCCGUUAGGCCGAA ACUAAUAU
10358


5586
UAUUAGUUA AUGAGCCA
940
UGGCUCAU CUGAUGAGGCCGUUAGGCCGAA AACUAAUA
10359


5596
UGAGCCAUC ACUAGAAG
941
CUUCUAGU CUGAUGAGGCCGUUAGGCCGAA AUGGCUCA
10360


5600
CCAUCACUA GAAGAAAA
942
UUUUCUUC CUGAUGAGGCCGUUAGGCCGAA AGUGAUGG
10361


5615
AAGCCCAUU UUCAACUG
943
CAGUUGAA CUGAUGAGGCCGUUAGGCCGAA AUGGGCUU
10362


5616
AGCCCAUUU UCAACUGC
944
GCAGUUGA CUGAUGAGGCCGUUAGGCCGAA AAUGGGCU
10363


5617
GCCCAUUUU CAACUGCU
945
AGCACUUG CUGAUGAGGCCGUUAGGCCGAA AAAUGGGC
10364


5618
CCCAUUUUC AACUGCUU
946
AAGCAGUU CUGAUGAGGCCGUUAGGCCGAA AAAAUGGG
10365


5626
CAACUGCUU UGAAACUU
947
AAGUUUCA CUGAUGAGGCCGUUAGGCCGAA AGCAGUUG
10366


5627
AACUGCUUU GAAACUUG
948
CAAGUUUC CUGAUGAGGCCGUUAGGCCGAA AAGCAGUU
10367


5634
UUGAAACUU GCCUGGGG
949
CCCCAGGC CUGAUGAGGCCGUUAGGCCGAA AGUUUCAA
10368


5644
CCUGGGGUC UGAGCAUG
950
CAUGCUCA CUGAUGAGGCCGUUAGGCCGAA ACCCCAGG
10369


5661
AUGGGAAUA GGGAGACA
951
UGUCUCCC CUGAUGAGGCCGUUAGGCCGAA AUUCCCAU
10370


5674
GACAGGGUA GGAAAGGG
952
CCCUUUCC CUGAUGAGGCCGUUAGGCCGAA ACCCUGUC
10371


5688
GGGCGCCUA CUCUUCAG
953
CUGAAGAG CUGAUGAGGCCGUUAGGCCGAA AGGCGCCC
10372


5691
CGCCUACUC UUCAGGGU
954
ACCCUGAA CUGAUGAGGCCGUUAGGCCGAA AGUAGGCG
10373


5693
CCUACUCUU CAGGGUCU
955
AGACCCUG CUGAUGAGGCCGUUAGGCCGAA AGAGUAGG
10374


5694
CUACUCUUC AGGGUCUA
956
UAGACCCU CUGAUGAGGCCGUUAGGCCGAA AAGAGUAG
10375


5700
UUCAGGGUC UAAAGAUC
957
GAUCUUUA CUGAUGAGGCCGUUAGGCCGAA ACCCUGAA
10376


5702
CAGGGUCUA AAGAUCAA
958
UUGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGACCCUG
10377


5708
CUAAAGAUC AAGUGGGC
959
GCCCACUU CUGAUGAGGCCGUUAGGCCGAA AUCUUUAG
10378


5719
GUGGGCCUU GGAUCGCU
960
AGCGAUCC CUGAUGAGGCCGUUAGGCCGAA AGGCCCAC
10379


5724
CCUUGGAUC GCUAAGCU
961
AGCUUAGC CUGAUGAGGCCGUUAGGCCGAA AUCCAAGG
10380


5728
GGAUCGCUA AGCUGGCU
962
AGCCAGCU CUGAUGAGGCCGUUAGGCCGAA AGCGAUCC
10381


5737
AGCUGGCUC UGUUUGAU
963
AUCAAACA CUGAUGAGGCCGUUAGGCCGAA AGCCAGCU
10382


5741
GGCUCUGUU UGAUGCUA
964
UAGCAUCA CUGAUGAGGCCGUUAGGCCGAA ACAGAGCC
10383


5742
GCUCUGUTU GAUGCUAU
965
AUAGCAUC CUGAUGAGGCCGUUAGGCCGAA AACAGAGC
10384


5749
UUGAUGCUA UUUAUGCA
966
UGCAUAAA CUGAUGAGGCCGUUAGGCCGAA AGCAUCAA
10385


5751
GAUGCUAUU UAUGCAAG
967
CUUGCAUA CUGAUGAGGCCGUUAGGCCGAA AUAGCAUC
10386


5752
AUGCUAUUU AUGCAAGU
968
ACUUGCAU CUGAUGAGGCCGUUAGGCCGAA AAUAGCAU
10387


5753
UGCUAUUUA UGCAAGUU
969
AACUUGCA CUGAUGAGGCCGUUAGGCCGAA AAAUAQCA
10388


5761
AUGCAAGUU AGGGUCUA
970
UAGACCCU CUGAUGAGGCCGUUAGGCCGAA ACUUGCAU
10389


5762
UGCAAGUUA GGGUCUAU
971
AUAGACCC CUGAUGAGGCCGUUAGGCCGAA AACUUGCA
10390


5767
GUUAGGGUC UAUGUAUU
972
AAUACAUA CUGAUGAGGCCGUUAGGCCGAA ACCCUAAC
10391


5769
UAGGGUCUA UGUAUUUA
973
UAAAUACA CUGAUGAGGCCGUUAGGCCGAA AGACCCUA
10392


5773
GUCUAUGUA UUUAGGAU
974
AUCCUAAA CUGAUGAGGCCGUUAGGCCGAA ACAUAGAC
10393


5775
CUAUGUAUU UAGGAUGC
975
GCAUCCUA CUGAUGAGGCCGUUAGGCCGAA AUACAUAG
10394


5776
UAUGUAUUU AGGAUGCG
976
CGCAUCCU CUGAUGAGGCCGUUAGGCCGAA AAUACAUA
10395


5777
AUGUAUUUA GGAUGCGC
977
GCGCAUCC CUGAUGAGGCCGUUAGGCCGAA AAAUACAU
10396


5788
AUGCGCCUA CUCUUCAG
978
CUGAAGAG CUGAUGAGGCCGUUAGGCCGAA AGGCGCAU
10397


5791
CGCCUACUC UUCAGGGU
954
ACCCUGAA CUGAUGAGGCCGUUAGGCCGAA AGUAGGCG
10373


5793
CCUACUCUU CAGGGUCU
955
AGACCCUG CUGAUGAGGCCGUUAGGCCGAA AGAGUAGG
10374


5794
CUACUCUUC AGGGUCUA
956
UAGACCOU CUGAUGAGGCCGUUAGGCCGAA AAGAGUAG
10375


5800
UUCAGGGUC UAAAGAUC
957
GAUCUUUA CUGAUGAGGCCGUUAGGCCGAA ACCCUGAA
10376


5802
CAGGGUCUA AAGAUCAA
958
UUGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGACCCUG
10377


5808
CUAAAGAUC AAGUGGGC
959
GCCCACUU CUGAUGAGGCCGUUAGGCCGAA AUCUUUAG
10378


5819
GUGGGCCUU GGAUCGCU
960
AGCGAUCC CUGAUGAGGCCGUUAGGCCGAA AGGCCCAC
10379


5824
CCUUGGAUC GCUAAGCU
961
AGCUUAGC CUGAUGAGGCCGUUAGGCCGAA AUCCAAGG
10380


5828
GGAUCGCUA AGCUGGCU
962
AGCCAGCU CUGAUGAGGCCGUUAGGCCGAA AGCGAUCC
10381


5837
AGCUGGCUC UGUUUGAU
963
AUCAAACA CUGAUGAGGCCGUUAGGCCGAA AGCCAGCU
10382


5841
GGCUCUGUU UGAUGCUA
964
UAGCAUCA CUGAUGAGGCCGUUAGGCCGAA ACAGAGCC
10383


5842
GCUCUGUUU GAUGCUAU
965
AUAGCAUC CUGAUGAGGCCGUUAGGCCGAA AACAGAGC
10384


5849
UUGAUGCUA UUUAUGCA
966
UGCAUAAA CUGAUGAGGCCGUUAGGCCGAA AGCAUCAA
10385


5851
GAUGCUAUU UAUGCAAG
967
CUUGCAUA CUGAUGAGGCCGUUAGGCCGAA AUAGCAUC
10386


5852
AUGCUAUUU AUGCAAGU
968
ACUUCCAU CUGAUGAGGCCGUUAGGCCGAA AAUAGCAU
10387


5853
UGCUAUUUA UGCAAGUU
969
AACUUGCA CUGAUGAGGCCGUUAGGCCGAA AAAUAGCA
10388


5861
AUGCAAGUU AGGGUCUA
970
UAGACCCU CUGAUGAGGCCGUUAGGCCGAA ACUUGCAU
10389


5862
UGCAAGUUA GGGUCUAU
971
AUAGACCC CUGAUGAGGCCGUUAGGCCGAA AACUUGCA
10390


5867
GUUAGGGUC UAUGUAUU
972
AAUACAUA CUGAUGAGGCCGUUAGGCCGAA ACCCUAAC
10391


5869
UAGGGUCUA UGUAUUUA
973
UAAAUACA CUGAUGAGGCCGUUAGGCCGAA AGACCCUA
10392


5873
GUCUAUGUA UUUAGGAU
974
AUCCUAAA CUGAUGAGGCCGUUAGGCCGAA ACAUAGAC
10393


5875
CUAUGUAUU UAGGAUGU
979
ACAUCCUA CUGAUGAGGCCGUUAGGCCGAA AUACAUAG
10398


5876
UAUGUAUUU AGGAUGUC
980
GACAUCCU CUGAUGAGGCCGUUAGGCCGAA AAUACAUA
10399


5877
AUGUAUUUA GGAUGUCU
981
AGACAUCC CUGAUGAGGCCGUUAGGCCGAA AAAUACAU
10400


5884
UAGGAUGUC UGCACCUU
982
AAGGUGCA CUGAUGAGGCCGUUAGGCCGAA ACAUCCUA
10401


5892
CUGCACCUU CUGCAGCC
983
GGCUGCAG CUGAUGAGGCCGUUAGGCCGAA AGGUGCAG
10402


5893
UGCACCUUC UGCAGCCA
984
UGGCUGCA CUGAUGAGGCCGUUAGGCCGAA AAGGUGCA
10403


5904
CAGCCAGUC AGAAGCUG
985
CAGCUUCU CUGAUGAGGCCGUUAGGCCGAA ACUGGCUG
10404


5930
CAGUGGAUU GCUGCUUC
986
GAAGCAGC CUGAUGAGGCCGUUAGGCCGAA AUCCACUG
10405


5937
UUGCUGCUU CUUGGGGA
987
UCCCCAAG CUGAUGAGGCCGUUAGGCCGAA AGCAGCAA
10406


5938
UGCUGCUUC UUGGGGAG
988
CUCCCCAA CUGAUGAGGCCGUUAGGCCGAA AAGCAGCA
10407


5940
CUGCUUCUU GGGGAGAA
989
UUCUCCCC CUGAUGAGGCCGUUAGGCCGAA AGAAGCAG
10408


5953
AGAAGAGUA UGCUUCCU
990
AGGAAGCA CUGAUGAGGCCGUUAGGCCGAA ACUCUUCU
10409


5958
AGUAUGCUU CCUUUUAU
991
AUAAAAGG CUGAUGAGGCCGUUAGGCCGAA AGCAUACU
10410


5959
GUAUGCUUC CUUUUAUC
992
GAUAAAAG CUGAUGAGGCCGUUAGGCCGAA AAGCAUAC
10411


5962
UGCUUCCUU UUAUCCAU
993
AUGGAUAA CUGAUGAGGCCGUUAGGCCGAA AGGAAGCA
10412


5963
GCUUCCUUU UAUCCAUG
994
CAUGGAUA CUGAUGAGGCCGUUAGGCCGAA AAGGAAGC
10413


5964
CUUCCUUUU AUCCAUGU
995
ACAUCGAU CUGAUGAGGCCGUUAGGCCGAA AAAGGAAG
10414


5965
UUCCUUUUA UCCAUGUA
996
UACAUGGA CUGAUGAGGCCGUUAGGCCGAA AAAAGGAA
10415


5967
CCUUUUAUC CAUGUAAU
997
AUUACAUG CUGAUGAGGCCGUUAGGCCGAA AUAAAAGG
10416


5973
AUCCAUGUA AUUUAACU
998
AGUUAAAU CUGAUGAGGCCGUUAGGCCGAA ACAUGGAU
10417


5976
CAUGUAAUU UAACUGUA
999
UACAGUUA CUGAUGAGGCCGUUAGGCCGAA AUUACAUG
10418


5977
AUGUAAUUU AACUGUAG
1000
CUACAGUU CUGAUGAGGCCGUUAGGCCGAA AAUUACAU
10419


5978
UGUAAUUUA ACUGUAGA
1001
UCUACAGU CUGAUGAGGCCGUUAGGCCGAA AAAUUACA
10420


5984
UUAACUGUA GAACCUGA
1002
UCAGGUUC CUGAUGAGGCCGUUAGGCCGAA ACAGUUAA
10421


5996
CCUGAGCUC UAAGUAAC
1003
GUUACUUA CUGAUGAGGCCGUUAGGCCGAA AGCUCAGG
10422


5998
UGAGCUCUA AGUAACCG
1004
CGGUUACU CUGAUGAGGCCGUUAGGCCGAA AGAGCUCA
10423


6002
CUCUAAGUA ACCGAAGA
1005
UCUUCGGU CUGAUGAGGCCGUUAGGCCGAA ACUUAGAG
10424


6015
AAGAAUGUA UGCCUCUG
1006
CAGAGGCA CUGAUGAGGCCGUUAGGCCGAA ACAUUCUU
10425


6021
GUAUGCCUC UGUUCUUA
1007
UAAGAACA CUGAUGAGGCCGUUAGGCCGAA AGGCAUAC
10426


6025
GCCUCUGUU CUUAUGUG
1008
CACAUAAG CUGAUGAGGCCGUUAGGCCGAA ACAGAGGC
10427


6026
CCUCUGUUC UUAUGUGC
1009
GCACAUAA CUGAUGAGGCCGUUAGGCCGAA AACAGAGG
10428


6028
UCUGUUCUU AUGUGCCA
1010
UGGCACAU CUGAUGAGGCCGUUAGGCCGAA AGAACAGA
10429


6029
CUGUUCUUA UGUGCCAC
1011
GUGGCACA CUGAUGAGGCCGUUAGGCCGAA AAGAACAG
10430


6040
UGCCACAUC CUUGUUUA
1012
UAAACAAG CUGAUGAGGCCGUUAGGCCGAA AUGUGGCA
10431


6043
CACAUCCUU GUUUAAAG
1013
CUUUAAAC CUGAUGAGGCCGUUAGGCCGAA AGGAUGUG
10432


6046
AUCCUUGUU UAAAGGCU
1014
AGCCUUUA CUGAUGAGGCCGUUAGGCCGAA ACAAGGAU
10433


6047
UCCUUGUUU AAAGGCUC
1015
GAGCCUUU CUGAUGAGGCCGUUAGGCCGAA AACAAGGA
10434


6048
CCUUGUUUA AAGGCUCU
1016
AGAGCCUU CUGAUGAGGCCGUUAGGCCGAA AAACAAGG
10435


6055
UAAAGGCUC UCUGUAUG
1017
CAUACAGA CUGAUGAGGCCGUUAGGCCGAA AGCCUUUA
10436


6057
AAGGCUCUC UGUAUGAA
1018
UUCAUACA CUGAUGAGGCCGUUAGGCCGAA AGAGCCUU
10437


6061
CUCUCUGUA UGAAGAGA
1019
UCUCUUCA CUGAUGAGGCCGUUAGGCCGAA ACAGAGAG
10438


6079
GGGACCGUC AUCAGCAC
1020
GUGCUGAU CUGAUGAGGCCGUUAGGCCGAA ACGGUCCC
10439


6082
ACCGUCAUC AGCACAUU
1021
AAUGUGCU CUGAUGAGGCCGUUAGGCCGAA AUGACGGU
10440


6090
CAGCACAUU CCCUAGUG
1022
CACUAGGG CUGAUGAGGCCGUUAGGCCGAA AUGUGCUG
10441


6091
AGCACAUUC CCUAGUGA
1023
UCACUAGG CUGAUGAGGCCGUUAGGCCGAA AAUGUGCU
10442


6095
CAUUCCCUA GUGAGCCU
1024
AGGCUCAC CUGAUGAGGCCGUUAGGCCGAA AGGGAAUG
10443


6104
GUGAGCCUA CUGGCUCC
1025
GGAGCCAG CUGAUGAGGCCGUUAGGCCGAA AGGCUCAC
10444


6111
UACUGGCUC CUGGCAGC
1026
GCUGCCAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGUA
10445


6124
CAGCGGCUU UUGUGGAA
1027
UUCCACAA CUGAUGAGGCCGUUAGGCCGAA AGCCGCUG
10446


6125
AGCGGCUUU UGUGGAAG
1028
CUUCCACA CUGAUGAGGCCGUUAGGCCGAA AAGCCGCU
10447


6126
GCGGCUUUU GUGGAAGA
1029
UCUUCCAC CUGAUGAGGCCGUUAGGCCGAA AAAGCCGC
10448


6137
GGAAGACUC ACUAGCCA
1030
UGGCUAGU CUGAUCAGGCCGUUAGGCCGAA AGUCUUCC
10449


6141
GACUCACUA GCCAGAAG
1031
CUUCUGGC CUGAUGAGGCCGUUAGGCCGAA AGUGAGUC
10450


6166
GGGACAGUC CUCUCCAC
1032
GUGGAGAG CUGAUGAGGCCGUUAGGCCGAA ACUGUCCC
10451


6169
ACAGUCCUC UCCACCAA
1033
UUGGUGGA CUGAUGAGGCCGUUAGGCCGAA AGGACUGU
10452


6171
AGUCCUCUC CACCAAGA
1034
UCUUCGUG CUGAUGAGGCCGUUAGGCCGAA AGAGGACU
10453


6181
ACCAAGAUC UAAAUCCA
1035
UGGAUUUA CUGAUGAGGCCGUUAGGCCGAA AUCUUGGU
10454


6183
CAAGAUCUA AAUCCAAA
1036
UUUGGAUU CUGAUGAGGCCGUUAGGCCGAA AGAUCUUG
10455


6187
AUCUAAAUC CAAACAAA
1037
UUUGUUUG CUGAUGAGGCCGUUAGGCCGAA AUUUAGAU
10456


6204
AGCAGGCUA GAGCCAGA
1038
UCUGGCUC CUGAUGAGGCCGUUAGGCCGAA AGCCUGCU
10457


6226
GGACAAAUC UUUGUUGU
1039
ACAACAAA CUGAUGAGGCCGUUAGGCCGAA AUUUGUCC
10458


6228
ACAAAUCUU UGUUGUUC
1040
GAACAACA CUGAUGAGGCCGUUAGGCCGAA AGAUUUGU
10459


6229
CAAAUCUUU GUUGUUCC
1041
GGAACAAC CUGAUGAGGCCGUUAGGCCGAA AAGAUUUG
10460


6232
AUCUUUGUU GUUCCUCU
1042
AGAGGAAC CUGAUGAGGCCGUUAGGCCGAA ACAAAGAU
10461


6235
UUUGUUGUU CCUCUUCU
1043
AGAAGAGG CUGAUGAGGCCGUUAGGCCGAA ACAACAAA
10462


6236
UUGUUGUUC CUCUUCUU
1044
AAGAAGAG CUGAUGAGGCCGUUAGGCCGAA AACAACAA
10463


6239
UUGUUCCUC UUCUUUAC
1045
GUAAAGAA CUGAUGAGGCCGUUAGGCCGAA AGGAACAA
10464


6241
GUUCCUCUU CUUUACAC
1046
GUGUAAAG CUGAUGAGGCCGUUAGGCCGAA AGAGGAAC
10465


6242
UUCCUCUUC UUUACACA
1047
UGUGUAAA CUGAUGAGGCCGUUAGGCCGAA AAGAGGAA
10466


6244
CCUCUUCUU UACACAUA
1048
UAUGUGUA CUGAUGAGGCCGUUAGGCCGAA AGAAGAGG
10467


6245
CUCUUCUUU ACACAUAC
1049
GUAUGUGU CUGAUGAGGCCGUUAGGCCGAA AAGAAGAG
10468


6246
UCUUCUUUA CACAUACG
1050
CGUAUGUG CUGAUGAGGCCGUUAGGCCGAA AAAGAAGA
10469


6252
UUACACAUA CGCAAACC
1051
GGUUUGCG CUGAUGAGGCCGUUAGGCCGAA AUGUGUAA
10470


6280
CUGGCAAUU UUAUAAAU
1052
AUUUAUAA CUGAUGAGGCCGUUAGGCCGAA AUUGCCAG
10471


6281
UGGCAAUUU UAUAAAUC
1053
GAUUUAUA CUGAUGAGGCCGUUAGGCCGAA AAUUGCCA
10472


6282
GGCAAUUUU AUAAAUCA
1054
UGAUUUAU CUGAUGAGGCCGUUAGGCCGAA AAAUUGCC
10473


6283
GCAAUUUUA UAAAUCAG
1055
CUGAUUUA CUGAUGAGGCCGUUAGGCCGAA AAAAUUGC
10474


6285
AAUUUUAUA AAUCAGGU
1056
ACCUGAUU CUGAUGAGGCCGUUAGGCCGAA AUAAAAUU
10475


6289
UUAUAAAUC AGGUAACU
1057
AGUUACCU CUGAUGAGGCCGUUAGGCCGAA AUUUAUAA
10476


6294
AAUCAGGUA ACUGGAAG
1058
CUUCCAGU CUGAUGAGGCCGUUAGGCCGAA ACCUGAUU
10477


6308
AAGGAGGUU AAACUCAG
1059
CUGAGUUU CUGAUGAGGCCGUUAGGCCGAA ACCUCCUU
10478


6309
AGGAGGUUA AACUCAGA
1060
UCUGAGUU CUGAUGAGGCCGUUAGGCCGAA AACCUCCU
10479


6314
GUUAAACUC AGAAAAAA
1061
UUUUUUCU CUGAUGAGGCCGUUAGGCCGAA AGUUUAAC
10480


6331
GAAGACCUC AGUCAAUU
1062
AAUUGACU CUGAUGAGGCCGUUAGGCCGAA AGGUCUUC
10481


6335
ACCUCAGUC AAUUCUCU
1063
AGAGAAUU CUGAUGAGGCCGUUAGGCCGAA ACUGAGGU
10482


6339
CAGUCAAUU CUCUACUU
1064
AAGUAGAG CUGAUGAGGCCGUUAGGCCGAA AUUGACUG
10483


6340
AGUCAAUUC UCUACUUU
1065
AAAGUAGA CUGAUGAGGCCGUUAGGCCGAA AAUUGACU
10484


6342
UCAAUUCUC UACUUUUU
1066
AAAAAGUA CUGAUGAGGCCGUUAGGCCGAA AGAAUUGA
10485


6344
AAUUCUCUA CUUUUUUU
1067
AAAAAAAG CUGAUGAGGCCGUUAGGCCGAA AGAGAAUU
10486


6347
UCUCUACUU UUUUUUUU
1068
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AGUAGAGA
10487


6348
CUCUACUUU UUUUUUUU
1069
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAGUAGAG
10488


6349
UCUACUUUU UUUUUUUU
1070
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAGUAGA
10489


6350
CUACUUUUU UUUUUUUU
1071
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAGUAG
10490


6351
UACUUUUUU UUUUUUUU
1072
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAGUA
10491


6352
ACUUUUUUU UUUUUUUU
1073
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAGU
10492


6353
CUUUUUUUU UUUUUUUU
1074
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAG
10493


6354
UUUUUUUUU UUUUUUUC
1075
GAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10494


6355
UUUUUUUUU UUUUUUCC
1076
GGAAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10495


6356
UUUUUUUUU UUUUUCCA
1077
UGGAAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10496


6357
UUUUUUUUU UUUUCCAA
1078
UUGGAAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10497


6358
UUUUUUUUU UUUCCAAA
1079
UUUGGAAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10498


6359
UUUUUUUUU UUCCAAAU
1080
AUUUGGAA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10499


6360
UUUUUUUUU UCCAAAUC
1081
GAUUUGGA CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10500


6361
UUUUUUUUU CCAAAUCA
1082
UGAUUUGG CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10501


6362
UUUUUUUUC CAAAUCAG
1083
CUGAUUUG CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10502


6368
UUCCAAAUC AGAUAAUA
1084
UAUUAUCU CUGAUGAGGCCGUUAGGCCGAA AUUUGGAA
10503


6373
AAUCAGAUA AUAGCCCA
1085
UGGGCUAU CUGAUGAGGCCGUUAGGCCGAA AUCUGAUU
10504


6376
CAGAUAAUA GCCCAGCA
1086
UGCUGGGC CUGAUGAGGCCGUUAGGCCGAA AUUAUCUG
10505


6388
CAGCAAAUA GUGAUAAC
1087
GUUAUCAC CUGAUGAGGCCGUUAGGCCGAA AUUUGCUG
10506


6394
AUAGUGAUA ACAAAUAA
1088
UUAUUUGU CUGAUGAGGCCGUUAGGCCGAA AUCACUAU
10507


6401
UAACAAAUA AAACCUUA
1089
UAAGGUUU CUGAUGAGGCCGUUAGGCCGAA AUUUGUUA
10508


6408
UAAAACCUU AGCUGUUC
1090
GAACAGCU CUGAUGAGGCCGUUAGGCCGAA AGGUUUUA
10509


6409
AAAACCUUA GCUGUUCA
1091
UGAACAGC CUGAUGAGGCCGUUAGGCCGAA AAGGUUUU
10510


6415
UUAGCUGUU CAUGUCUU
1092
AAGACAUG CUGAUGAGGCCGUUAGGCCGAA ACAGUCAA
10511


6416
UAGCUGUUC AUGUCUUG
1093
CAAGACAU CUGAUGAGGCCGUUAGGCCGAA AACAGCUA
10512


6421
GUUCAUGUC UUGAUUUC
1094
GAAAUCAA CUGAUGAGGCCGUUAGGCCGAA ACAUGAAC
10513


6423
UCAUGUCUU GAUUUCAA
1095
UUGAAAUC CUGAUGAGGCCGUUAGGCCGAA AGACAUGA
10514


6427
GUCUUGAUU UCAAUAAU
1096
AUUAUUGA CUGAUGAGGCCGUUAGGCCGAA AUCAAGAC
10515


6428
UUTUGAUUU CAAUAAUU
1097
AAUUAUUG CUGAUGAGGCCGUUAGGCCGAA AAUCAAGA
10516


6429
CUUGAUUUC AAUAAUUA
1098
UAAUUAUU CUGAUGAGGCCGUUAGGCCGAA AAAUCAAG
10517


6433
AUUUCAAUA AUUAAUUC
1099
GAAUUAAU CUGAUGAGGCCGUUAGGCCGAA AUUGAAAU
10518


6436
UCAAUAAUU AAUUCUUA
1100
UAAGAAUU CUGAUGAGGCCGUUAGGCCGAA AUUAUUGA
10519


6437
CAAUAAUUA AUUCUUAA
1101
UUAAGAAU CUGAUGAGGCCGUUAGGCCGAA AAUUAUUG
10520


6440
UAAUUAATU CUUAAUCA
1102
UGAUUAAG CUGAUGAGGCCGUUAGGCCGAA AUUAAUUA
10521


6441
AAUUAAUUC UUAAUCAU
1103
AUGAUUAA CUGAUGAGGCCGUUAGGCCGAA AAUUAAUU
10522


6443
UUAAUUCUU AAUCAUUA
1104
UAAUGAUU CUGAUGAGGCCGUUAGGCCGAA AGAAUUAA
10523


6444
UAAUUCUUA AUCAUUAA
1105
UUAAUGAU CUGAUGAGGCCGUUAGGCCGAA AAGAAUUA
10524


6447
UUCUUAAUC AUUAAGAG
1106
CUCUUAAU CUGAUGAGGCCGUUAGGCCGAA AUUAAGAA
10525


6450
UUAAUCAUU AAGAGACC
1107
GGUCUCUU CUGAUGAGGCCGUUAGGCCGAA AUGAUUAA
10526


6451
UAAUCAUUA AGAGACCA
1108
UGGUCUCU CUGAUGAGGCCGUUAGGCCGAA AAUGAUUA
10527


6461
GAGACCAUA AUAAAUAC
1109
GUAUUUAU CUGAUGAGGCCGUUAGGCCGAA AUGGUCUC
10528


6464
ACCAUAAUA AAUACUCC
1110
GGAGUAUU CUGAUGAGGCCGUUAGGCCGAA AUUAUGGU
10529


6468
UAAUAAAUA CUCCUUUU
1111
AAAAGGAG CUGAUGAGGCCGUUAGGCCGAA AUUUAUUA
10530


6471
UAAAUACUC CUUUUCAA
1112
UUGAAAAG CUGAUGAGGCCGUUAGGCCGAA AGUAUUUA
10531


6474
AUACUCCUU UUCAAGAG
1113
CUCUUGAA CUGAUGAGGCCGUUAGGCCGAA AGGAGUAU
10532


6475
UACUCCUUU UCAAGAGA
1114
UCUCUUGA CUGAUGAGGCCGUUAGGCCGAA AAGGAGUA
10533


6476
ACUCCUUUU CAAGAGAA
1115
UUCUCUUG CUGAUGAGGCCGUUAGGCCGAA AAAGGAGU
10534


6477
CUCCUUUUC AAGAGAAA
1116
UUUCUCUU CUGAUGAGGCCGUUAGGCCGAA AAAAGGAG
10535


6497
AAAACCAUU AGAAUUGU
1117
ACAAUUCU CUGAUGAGGCCGUUAGGCCGAA AUGGUUUU
10536


6498
AAACCAUUA GAAUUGUU
1118
AACAAUUC CUGAUGAGGCCGUUAGGCCGAA AAUGGUUU
10537


6503
AUUAGAAUU GUUACUCA
1119
UGAGUAAC CUGAUGAGGCCGUUAGGCCGAA AUUCUAAU
10538


6506
AGAAUUGUU ACUCAGCU
1120
AGCUGAGU CUGAUGAGGCCGUUAGGCCGAA ACAAUUCU
10539


6507
GAAUUGUUA CUCAGCUC
1121
GACCUGAG CUGAUGAGGCCGUUAGGCCGAA AACAAUUC
10540


6510
UUGUUACUC AGCUCCUU
1122
AAGGAGCU CUGAUGAGGCCGUUAGGCCGAA AGUAACAA
10541


6515
ACUCAGCUC CUUCAAAC
1123
GUUUGAAG CUGAUGAGGCCGUUAGGCCGAA AGCUGAGU
10542


6518
CAGCUCCUU CAAACUCA
1124
UGAGUUUG CUGAUGAGGCCGUUAGGCCGAA AGGAGCUG
10543


6519
AGCUCCUUC AAACUCAG
1125
CUGAGUUU CUGAUGAGGCCGUUAGGCCGAA AAGGAGCU
10544


6525
UUCAAACUC AGGUUUCU
1126
ACAAACCU CUGAUGAGGCCGUUAGGCCGAA AGUUUGAA
10545


6530
ACUCAGGUU UGUAGCAU
1127
AUGCUACA CUGAUGAGGCCGUUAGGCCGAA ACCUGAGU
10546


6531
CUCAGGUUU GUAGCAUA
1128
UAUGCUAC CUGAUGAGGCCGUUAGGCCGAA AACCUGAG
10547


6534
AGGUUUGUA GCAUACAU
1129
AUGUAUGC CUGAUGAGGCCGUUAGGCCGAA ACAAACCU
10548


6539
UGUAGCAUA CAUGAGUC
1130
GACUCAUG CUGAUGAGGCCGUUAGGCCGAA AUGCUACA
10549


6547
ACAUGAGUC CAUCCAUC
1131
GAUGGAUG CUGAUGAGGCCGUUAGGCCGAA ACUCAUGU
10550


6551
GAGUCCAUC CAUCAGUC
1132
GACUGAUG CUGAUGAGGCCGUUAGGCCGAA AUGGACUC
10551


6555
CCAUCCAUC AGUCAAAG
1133
CUUUGACU CUGAUGAGGCCGUUAGGCCGAA AUGGAUGG
10552


6559
CCAUCAGUC AAAGAAUG
1134
CAUUCUUU CUGAUGAGGCCGUUAGGCCGAA ACUGAUGG
10553


6570
AGAAUGGUU CCAUCUGG
1135
CCAGAUGG CUGAUGAGGCCGUUAGGCCGAA ACCAUUCU
10554


6571
GAAUGGUUC CAUCUGGA
1136
UCCAGAUG CUGAUGAGGCCGUUAGGCCGAA AACCAUUC
10555


6575
GGUUCCAUC UGGAGUCU
1137
AGACUCCA CUGAUGAGGCCGUUAGGCCGAA AUGGAACC
10556


6582
UCUGCAGUC UUAAUGUA
1138
UACAUUAA CUGAUGAGGCCGUUAGGCCGAA ACUCCAGA
10557


6584
UGGAGUCUU AAUGUAGA
1139
UCUACAUU CUGAUGAGGCCGUUAGGCCGAA AGACUCCA
10558


6585
GGAGUCUUA AUGUAGAA
1140
UUCUACAU CUGAUGAGGCCGUUAGGCCGAA AAGACUCC
10559


6590
CUUAAUGUA GAAAGAAA
1141
UUUCUUUC CUGAUGAGGCCGUUAGGCCGAA ACAUUAAG
10560


6609
UGGAGACUU GUAAUAAU
1142
AUUAUUAC CUGAUGAGGCCGUUAGGCCGAA AGUCUCCA
10561


6612
AGACUUGUA AUAAUGAG
1143
CUCAUUAU CUGAUGAGGCCGUUAGGCCGAA ACAAGUCU
10562


6615
CUUGUAAUA AUGAGCUA
1144
UAGCUCAU CUGAUGAGGCCGUUAGGCCGAA AUUACAAG
10563


6623
AAUGAGCUA GUUACAAA
1145
UUUGUAAC CUGAUGAGGCCGUUAGGCCGAA AGCUCAUU
10564


6626
GAGCUAGUU ACAAAGUG
1146
CACUUUGU CUGAUGAGGCCGUUAGGCCGAA ACUAGCUC
10565


6627
AGCUAGUUA CAAAGUGC
1147
GCACUUUG CUGAUGAGGCCGUUAGGCCGAA AACUAGCU
10566


6637
AAAGUGCUU GUUCAUUA
1148
UAAUGAAC CUGAUGAGGCCGUUAGGCCGAA AGCACUUU
10567


6640
GUGCUUGUU CAUUAAAA
1149
UUUUAAUG CUGAUGAGGCCGUUAGGCCGAA ACAAGCAC
10568


6641
UGCUUGUUC AUUAAAAU
1150
AUUUUAAU CUGAUGAGGCCGUUAGGCCGAA AACAAGCA
10569


6644
UUGUUCAUU AAAAUAGC
1151
GCUAUUUU CUGAUGAGGCCGUUAGGCCGAA AUGAACAA
10570


6645
UGUUCAUUA AAAUAGCA
1152
UGCUAUUU CUGAUGAGGCCGUUAGGCCGAA AAUGAACA
10571


6650
AUUAAAAUA GCACUGAA
1153
UUCAGUGC CUGAUGAGGCCGUUAGGCCGAA AUUUUAAU
10572


6662
CUGAAAAUU GAAACAUG
1154
CAUGUUUC CUGAUGAGGCCGUUAGGCCGAA AUUUUCAG
10573


6674
ACAUGAAUU AACUGAUA
1155
UAUCAGUU CUGAUGAGGCCGUUAGGCCGAA AUUCAUGU
10574


6675
CAUGAAUUA ACUGAUAA
1156
UUAUCAGU CUGAUGAGGCCGUUAGGCCGAA AAUUCAUG
10575


6682
UAACUGAUA AUAUUCCA
1157
UGGAAUAU CUGAUGAGGCCGUUAGGCCGAA AUCAGUUA
10576


6685
CUGAUAAUA UUCCAAUC
1158
GAUUGGAA CUGAUGAGGCCGUUAGGCCGAA AUUAUCAG
10577


6687
GAUAAUAUU CCAAUCAU
1159
AUGAUUGG CUGAUGAGGCCGUUAGGCCGAA AUAUUAUC
10578


6688
AUAAUAUUC CAAUCAUU
1160
AAUGAUUG CUGAUGAGGCCGUUAGGCCGAA AAUAUUAU
10579


6693
AUUCCAAUC AUUUGCCA
1161
UGGCAAAU CUGAUGAGGCCGUUAGGCCGAA AUUGGAAU
10580


6696
CCAAUCAUU UGCCAUUU
1162
AAAUGGCA CUGAUGAGGCCGUUAGGCCGAA AUGAUUGG
10581


6697
CAAUCAUUU GCCAUUUA
1163
UAAAUGGC CUGAUGAGGCCGUUAGGCCGAA AAUGAUUG
10582


6703
UUUGCCAUU UAUGACAA
1164
UUGUCAUA CUGAUGAGGCCGUUAGGCCGAA AUGGCAAA
10583


6704
UUGCCAUUU AUGACAAA
1165
UUUGUCAU CUGAUGAGGCCGUUAGGCCGAA AAUGGCAA
10584


6705
UGCCAUUUA UGACAAAA
1166
UUUUGUCA CUGAUGAGGCCGUUAGGCCGAA AAAUGGCA
10585


6719
AAAAUGGUU GGCACUAA
1167
UUAGUGCC CUGAUGAGGCCGUUAGGCCGAA ACCAUUUU
10586


6726
UUGGCACUA ACAAAGAA
1168
UUCUUUGU CUGAUGAGGCCGUUAGGCCGAA AGUGCCAA
10587


6743
CGAGCACUU CCUUUCAG
1169
CUGAAAGG CUGAUGAGGCCGUUAGGCCGAA AGUGCUCG
10588


6744
GAGCACUUC CUUUCAGA
1170
UCUGAAAG CUGAUGAGGCCGUUAGGCCGAA AAGUGCUC
10589


6747
CACUUCCUU UCAGAGUU
1171
AACUCUGA CUGAUGAGGCCGUUAGGCCGAA AGGAAGUG
10590


6748
ACUUCCUUU CAGAGUUU
1172
AAACUCUG CUGAUGAGGCCGUUAGGCCGAA AAGGAAGU
10591


6749
CUUCCUUUC AGAGUUUC
1173
GAAACUCU CUGAUGAGGCCGUUAGGCCGAA AAAGGAAG
10592


6755
UUCAGAGUU UCUGAGAU
1174
AUCUCAGA CUGAUGAGGCCGUUAGGCCGAA ACUCUGAA
10593


6756
UCAGAGUUU CUGAGAUA
1175
CAUCUCAG CUGAUGAGGCCGUUAGGCCGAA AACUCUGA
10594


6757
CAGAGUUUC UGAGAUAA
1176
UGAUCUCA CUGAUGAGGCCGUUAGGCCGAA AAACUCUG
10595


6764
UCUGAGAGA AUGUACGU
1177
ACGUACAU CUGAUGAGGCCGUUAGGCCGAA AUCUCAGA
10596


6769
GAUAAUGUA CGUGGAAC
1178
GUUCCACG CUGAUGAGGCCGUUAGGCCGAA ACAUUAUC
10597


6781
GGAACAGUC UGGGUGGA
1179
UCCACCCA CUGAUGAGGCCGUUAGGCCGAA ACUGUUCC
10598


6814
GUGCAAGUC UGUGUCUU
1180
AAGACACA CUGAUGAGGCCGUUAGGCCGAA ACUUGCAC
10599


6820
GUCUGUGUC UUGUCAGU
1181
ACUGACAA CUGAUGAGGCCGUUAGGCCGAA ACACAGAC
10600


6822
CUGUGUCUU GUCAGUCC
1182
GGACUGAC CUGAUGAGGCCGUUAGGCCGAA AGACACAG
10601


6825
UGUCCUGUC AGUCCAAG
1183
CUUGGACU CUGAUGAGGCCGUUAGGCCGAA ACAAGACA
10602


6829
UGGUCAGUC CAAGAAGU
1184
ACUUCUUG CUGAUGAGGCCGUUAGGCCGAA ACUGACAA
10603


6851
CGAGAUGUU AAUUUUAG
1185
CUAAAAUU CUGAUGAGGCCGUUAGGCCGAA ACAUCUCG
10604


6852
GAGAUGUGA AUUUUAGG
1186
CCUAAAAU CUGAUGAGGCCGUUAGGCCGAA AACAUCUC
10605


6855
AUGUUAAUU UUAGGGAC
1187
GUCCCUAA CUGAUGAGGCCGUUAGGCCGAA AUUAACAU
10606


6856
UGUUAAUUU UAGGGACC
1188
GGUCCCUA CUGAUGAGGCCGUUAGGCCGAA AAUUAACA
10607


6857
GUUAAUUUU AGGGACCC
1189
GGGUCCCU CUGAUGAGGCCGUUAGGCCGAA AAAUUAAC
10608


6858
UUAAUUUUA GGGACCCG
1190
CGGGUCCC CUGAUGAGGCCGUUAGGCCGAA AAAAUUAA
10609


6872
CCGUGCCUU GUUUCCUA
1191
UAGGAAAC CUGAUGAGGCCGUUAGGCCGAA AGGCACGG
10610


6875
UGCCUUGUU UCCUAGCC
1192
GGCUAGGA CUGAUGAGGCCGUUAGGCCGAA ACAAGGCA
10611


6876
GCCUUGUUU CCUAGCCC
1193
GGGCUAGG CUGAUGAGGCCGUUAGGCCGAA AACAAGGC
10612


6877
CCUUGUUUC CUAGCCCA
1194
UGGGCUAG CUGAUGAGGCCGUUAGGCCGAA AAACAAGG
10613


6880
UGUUUCCUA GCCCACAA
1195
UUGUGGGC CUGAUGAGGCCGUUAGGCCGAA AGGAAACA
10614


6901
GCAAACAUC AAACAGAU
1196
AUCUGUUU CUGAUGAGGCCGUUAGGCCGAA AUGUGUGC
10615


6910
AAACAGAUA CUCGCUAG
1197
CUAGCGAG CUGAUGAGGCCGUUAGGCCGAA AUCUGUUU
10616


6913
CAGAUACUC GCUAGCCU
1198
AGGCUAGC CUGAUGAGGCCGUUAGGCCGAA AGUAUCUG
10617


6917
UACUCGCUA GCCUCAUU
1199
AAUGAGGC CUGAUGAGGCCGUUAGGCCGAA AGCGAGUA
10618


6922
GCUAGCCUC AUUUAAAU
1200
AUUUAAAU CUGAUGAGGCCGUUAGGCCGAA AGGCUAGC
10619


6925
AGCCUCAUU UAAAUUGA
1201
UCAAUUUA CUGAUGAGGCCGUUAGGCCGAA AUGAGGCU
10620


6926
GCCUCAUUU AAAUUGAU
1202
AUCAAUUU CUGAUGAGGCCGUUAGGCCGAA AAUGAGGC
10621


6927
CCUCAUUUA AAUUGAUU
1203
AAUCAAUU CUGAUGAGGCCGUUAGGCCGAA AAAUGAGG
10622


6931
AUUUAAAUU GAUUAAAG
1204
CUUUAAUC CUGAUGAGGCCGUUAGGCCGAA AUUUAAAU
10623


6935
AAAUUGAUU AAAGGAGG
1205
CCUCCUUU CUGAUGAGGCCGUUAGGCCGAA AUCAAUUU
10624


6936
AAUUGAUUA AAGGAGGA
1206
UCCUCCUG CUGAUGAGGCCGUUAGGCCGAA AAUCAAUU
10625


6951
GAGUGCAUC UUUGGCCG
1207
CGGCCAAA CUGAUGAGGCCGUUAGGCCGAA AUGCACUC
10626


6953
GUGCAUCUU UGGCCGAC
1208
GUCGGCCA CUGAUGAGGCCGUUAGGCCGAA AGAUGCAC
10627


6954
UGCAUCUUU GGCCGACA
1209
UGUCGGCC CUGAUGAGGCCGUUAGGCCGAA AAGAUGCA
10628


6970
AGUGGUGGA ACUGUGUG
1210
CACACAGU CUGAUGAGGCCGUUAGGCCGAA ACACCACU
10629


7026
GUGGGUGUA UGUGUGUU
1211
AACACACA CUGAUGAGGCCGUUAGGCCGAA ACACCCAC
10630


7034
AUGUGUGUU UUGUGCAU
1212
AUGCACAA CUGAUGAGGCCGUUAGGCCGAA ACACACAU
10631


7035
UGUGUGUUU UGUGCAUA
1213
UAUGCACA CUGAUGAGGCCGUUAGGCCGAA AACACACA
10632


7036
GUGUGUGUG GUGCAUAA
1214
UUAUGCAC CUGAUGAGGCCGUUAGGCCGAA AAACACAC
10633


7043
UUGUGCAUA ACUAUUUA
1215
UAAAUAGU CUGAUGAGGCCGUUAGGCCGAA AUGCACAA
10634


7047
GCAUAACUA UUUAAGGA
1216
UCCUUAAA CUGAUGAGGCCGUUAGGCCGAA AGUUAUGC
10635


7049
AUAACUAUU UAAGGAAA
1217
UUUCCUUA CUGAUGAGGCCGUUAGGCCGAA AUAGUUAU
10636


7050
UAACUAUUU AAGGAAAC
1218
GUUUCCUU CUGAUGAGGCCGUUAGGCCGAA AAUAGUUA
10637


7051
AACUAUUUA AGGAAACU
1219
AGUUUCCU CUGAUGAGGCCGUUAGGCCGAA AAAUAGUU
10638


7065
ACUGGAAUU UUAAAGUU
1220
AACUUUAA CUGAUGAGGCCGUUAGGCCGAA AUUCCAGU
10639


7066
CUGGAAUUU UAAAGUUA
1221
UAACUUUA CUGAUGAGGCCGUUAGGCCGAA AAUUCCAG
10640


7067
UGGAAUUUU AAAGUUAC
1222
GUAACUUU CUGAUGAGGCCGUUAGGCCGAA AAAUUCCA
10641


7068
GGAAUUUUA AAGUUACU
1223
AGUAACUU CUGAUGAGGCCGUUAGGCCGAA AAAAUUCC
10642


7073
UUUAAAGUU ACUUUUAU
1224
AUAAAAGU CUGAUGAGGCCGUUAGGCCGAA ACUUUAAA
10643


7074
UUAAAGUUA CUUUUAUA
1225
UAUAAAAG CUGAUGAGGCCGUUAGGCCGAA AACUUUAA
10644


7077
AAGUUACUU UUAUACAA
1226
UUGUAUAA CUGAUGAGGCCGUUAGGCCGAA AGUAACUU
10645


7078
AGUUACUUU UAUACAAA
1227
UUUGUAUA CUCAUGAGGCCGUUAGGCCGAA AAGUAACU
10646


7079
GUUACUUUU AUACAAAC
1228
GUUUGUAU CUGAUGAGGCCGUUAGGCCGAA AAAGUAAC
10647


7080
UUACUUUUA UACAAACC
1229
GGUUUGUA CUGAUGAGGCCGUUAGGCCGAA AAAAGUAA
10648


7082
ACUUUUAUA CAAACCAA
1230
UUGGUUUG CUGAUGAGGCCGUUAGGCCGAA AUAAAAGU
10649


7095
CCAAGAAUA UAUGCUAC
1231
GUAGCAUA CUGAUGAGGCCGUUAGGCCGAA AUUCUUGG
10650


7097
AAGAAUAUA UGCUACAG
1232
CUGUAGCA CUGAUGAGGCCGUUAGGCCGAA AUAUUCUU
10651


7102
UAUAUGCUA CAGAUAUA
1233
UAUAUCUG CUGAUGAGGCCGUUAGGCCGAA AGCAUAUA
10652


7108
CUACAGAUA UAAGACAG
1234
CUGUCUUA CUGAUGAGGCCGUUAGGCCGAA AUCUGUAG
10653


7110
ACAGAUAUA AGACAGAC
1235
GUCUGUCU CUGAUGAGGCCGUUAGGCCGAA AUAUCUGU
10654


7124
GACAUGGUU UGGUCCUA
1236
UAGGACCA CUGAUGAGGCCGUUAGGCCGAA ACCAUGUC
10655


7125
ACAUGGUUU GGUCCUAU
1237
AUAGGACC CUGAUGAGGCCGUUAGGCCGAA AACCAUGU
10656


7129
GGUUUGGUC CUAUAUUU
1238
AAAUAUAG CUGAUGAGGCCGUUAGGCCGAA ACCAAACC
10657


7132
UUGGUCCUA UAUUUCUA
1239
UAGAAAUA CUGAUGAGGCCGUUAGGCCGAA AGGACCAA
10658


7134
UGUCCUAGA UUUCUAGU
1240
ACUAGAAA CUGAUGAGGCCGUUAGGCCGAA AUAGGACC
10659


7136
UCCUAUAUU UCUAGUCA
1241
UGACUAGA CUGAUGAGGCCGUUAGGCCGAA AUAUAGGA
10660


7137
CCUAUAUUU CUAGUCAU
1242
AUGACUAG CUGAUGAGGCCGUUAGGCCGAA AAUAUAGG
10661


7138
CUAUAUUUC UAGUCAUG
1243
CAUGACUA CUGAUGAGGCCGUUAGGCCGAA AAAUAUAG
10662


7140
AUAUUUCUA GUCAUGAU
1244
AUCAUGAC CUGAUGAGGCCGUUAGGCCGAA AGAAAUAU
10663


7143
UUUCUAGUC AUGAUGAA
1245
GUCAUCAG CUGAUGAGGCCGUUAGGCCGAA ACUAGAAA
10664


7155
AUGAAUGUA UUUUGUAU
1246
AUACAAAA CUGAUGAGGCCGUUAGGCCGAA ACAUUCAU
10665


7157
GAAUGUAUU UUGUAUAC
1247
GUAUACAA CUGAUGAGGCCGUUAGGCCGAA AUACAUUC
10666


7158
AAUGUAUUU UGUAUACC
1248
GGUAUACA CUGAUGAGGCCGUUAGGCCGAA AAUACAUU
10667


7159
AUGUAUUUU GUAUACCA
1249
UGGUAUAC CUGAUGAGGCCGUUAGGCCGAA AAAUACAU
10668


7162
UAUUUUGUA UACCAUCU
1250
AGAUGGUA CUGAUGAGGCCGUUAGGCCGAA ACAAAAUA
10669


7164
UUUUGUAUA CCAUCUUC
1251
GAAGAUGG CUGAUGAGGCCGUUAGGCCGAA AUACAAAA
10670


7169
UAUACCAUC UUCAUAUA
1252
UAUAUGAA CUGAUGAGGCCGUUAGGCCGAA AUGGUAUA
10671


7171
UACCAUCUU CAUAUAAU
1253
AUUAUAUG CUGAUGAGGCCGUUAGGCCGAA AGAUGGUA
10672


7172
ACCAUCUUC AUAUAAUA
1254
UAUUAUAU CUGAUGAGGCCGUUAGGCCGAA AAGAUGGU
10673


7175
AUCUUCAUA UAAUAUAC
1255
GUAUAUUA CUGAUGAGGCCGUUAGGCCGAA AUGAAGAU
10674


7177
CUUCAUAUA AUAUACUU
1256
AAGUAUAU CUGAUGAGGCCGUUAGGCCGAA AUAUGAAG
10675


7180
CAUAUAAUA UACUUAAA
1257
UUUAAGUA CUGAUGAGGCCGUUAGGCCGAA AUUAUAUG
10676


7182
UAUAAUAUA CUUAAAAA
1258
UUUUUAAG CUGAUGAGGCCGUUAGGCCGAA AUAUUAUA
10677


7185
AAUAUACUU AAAAAUAU
1259
AUAUUUUU CUGAUGAGGCCGUUAGGCCGAA AGUAUAUU
10678


7186
AUAUACUUA AAAAUAUU
1260
AAUAUUUU CUGAUGAGGCCGUUAGGCCGAA AAGUAUAU
10679


7192
UUAAAAAUA UUUCUUAA
1261
UUAAGAAA CUGAUGAGGCCGUUAGGCCGAA AUUUUUAA
10680


7194
AAAAAUAUU UCUUAAUU
1262
AAUUAAGA CUGAUGAGGCCGUUAGGCCGAA AUAUUUUU
10681


7195
AAAAUAUUU CUUAAUUG
1263
CAAUUAAG CUGAUGAGGCCGUUAGGCCGAA AAUAUUUU
10682


7196
AAAUAUUUC UUAAUUGG
1264
CCAAUUAA CUGAUGAGGCCGUUAGGCCGAA AAAUAUUU
10683


7198
AUAUUUCUU AAUUGGGA
1265
UCCCAAUU CUGAUGAGGCCGUUAGGCCGAA AGAAAUAU
10684


7199
UAUUUCUUA AUUGGGAU
1266
AUCCCAAU CUGAUGAGGCCGUUAGGCCGAA AAGAAAUA
10685


7202
UUCUUAAUU GGGAUUUG
1267
CAAAUCCC CUGAUGAGGCCGUUAGGCCGAA AUUAAGAA
10686


7208
AUUGGGAUU UGUAAUCG
1268
CGAUUACA CUGAUGAGGCCGUUAGGCCGAA AUCCCAAU
10687


7209
UUGGGAUUU GUAAUCGU
1269
ACGAUUAC CUGAUGAGGCCGUUAGGCCGAA AAUCCCAA
10688


7212
GGAUUUGUA AUCGUACC
1270
GGUACGAU CUGAUGAGGCCGUUAGGCCGAA ACAAAUCC
10689


7215
UUUGUAAUC GUACCAAC
1271
GUUGGUAC CUGAUGAGGCCGUUAGGCCGAA AUUACAAA
10690


7218
GUAAUCGUA CCAACUUA
1272
UAAGUUGG CUGAUGAGGCCGUUAGGCCGAA ACGAUUAC
10691


7225
UACCAACUU AAUUGAUA
1273
UAUCAAUU CUGAUGAGGCCGUUAGGCCGAA AGUUGGUA
10692


7226
ACCAACUUA AUUGAUAA
1274
UUAUCAAU CUGAUGAGGCCGUUAGGCCGAA AAGUUGGU
10693


7229
AACUUAAUU GAUAAACU
1275
AGUUUAUC CUGAUGAGGCCGUUAGGCCGAA AUUAAGUU
10694


7233
UAAUUGAUA AACUUGGC
1276
GCCAAGUU CUGAUGAGGCCGUUAGGCCGAA AUCAAUUA
10695


7238
GAUAAACUU GGCAACUG
1277
CAGUUGCC CUGAUGAGGCCGUUAGGCCGAA AGUUUAUC
10696


7249
CAACUGCUU UUAUGUUC
1278
GAACAUAA CUGAUGAGGCCGUUAGGCCGAA AGCAGUUG
10697


7250
AACUGCUUU UAUGUUCU
1279
AGAACAUA CUGAUGAGGCCGUUAGGCCGAA AAGCAGUU
10698


7251
ACUGCUUUU AUGUUCUG
1280
CAGAACAU CUGAUGAGGCCGUUAGGCCGAA AAAGCAGU
10699


7252
CUGCUUUUA UGUUCUGU
1281
ACAGAACA CUGAUGAGGCCGUUAGGCCGAA AAAAGCAG
10700


7256
UUUUAUGUU CUGUCUCC
1282
GGAGACAG CUGAUGAGGCCGUUAGGCCGAA ACAUAAAA
10701


7257
UUUAUGUUC UGUCUCCU
1283
AGGAGACA CUGAUGAGGCCGUUAGGCCGAA AACAUAAA
10702


7261
UGUUCUGUC UCCUUCCA
1284
UGGAAGGA CUGAUGAGGCCGUUAGGCCGAA ACAGAACA
10703


7263
UUCUGUCUC CUUCCAUA
1285
UAUGGAAG CUGAUGAGGCCGUUAGGCCGAA AGACAGAA
10704


7266
UGUCUCCUU CCAUAAAU
1286
AUUUAUGG CUGAUGAGGCCGUUAGGCCGAA AGGAGACA
10705


7267
GUCUCCUUC CAUAAAUU
1287
AAUUUAUG CUGAUGAGGCCGUUAGGCCGAA AAGGAGAC
10706


7271
CCLUUCAUA AAUUUUUC
1288
GAAAAAUU CUGAUGAGGCCGUUAGGCCGAA AUGGAAGG
10707


7275
CCAUAAAUU UUUCAAAA
1289
UUUUGAAA CUGAUGAGGCCGUUAGGCCGAA AUUUAUGG
10708


7276
CAUAAAUUU UUCAAAAU
1290
AUUUUGAA CUGAUGAGGCCGUUAGGCCGAA AAUUUAUG
10709


7277
AUAAAUUUU UCAAAAUA
1291
UAUUUUGA CUGAUGAGGCCGUUAGGCCGAA AAAUUUAU
10710


7278
UAAAUUUUU CAAAAUAC
1292
GUAUUUUG CUGAUGAGGCCGUUAGGCCGAA AAAAUUUA
10711


7279
AAAUUUUUC AAAAUACU
1293
AGUAUUUU CUGAUGAGGCCGUUAGGCCGAA AAAAAUUU
10712


7285
UUCAAAAUA CUAAUUCA
1294
UGAAUUAG CUGAUGAGGCCGUUAGGCCGAA AUUUUGAA
10713


7288
AAAAUACUA AUUCAACA
1295
UGUUGAAU CUGAUGAGGCCGUUAGGCCGAA AGUAUUUU
10714


7291
AUACUAAUU CAACAAAG
1296
CUUUGUUG CUGAUGAGGCCGUUAGGCCGAA AUUAGUAU
10715


7292
UACUAAUUC AACAAAGA
1297
UCUUUGUU CUGAUGAGGCCGUUAGGCCGAA AAUUAGUA
10716


7308
AAAAAGCUC UUUUUUUU
1298
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA AGCUUUUU
10717


7310
AAAGCUCUU UUUUUUCC
1299
GGAAAAAA CUGAUGAGGCCGUUAGGCCGAA AGAGCUUU
10718


7311
AAGCUCUUU UUUUUCCU
1300
AGGAAAAA CUGAUGAGGCCGUUAGGCCGAA AAGAGCUU
10719


7312
AGCUCUUUU UUUUCCUA
1301
UAGGAAAA CUGAUGAGGCCGUUAGGCCGAA AAAGAGCU
10720


7313
GCUCUUTUU UUUCCUAA
1302
UUAGGAAA CUGAUGAGGCCGUUAGGCCGAA AAAAGAGC
10721


7314
CUCUUUUUU UUCCUAAA
1303
UUUAGGAA CUGAUGAGGCCGUUAGGCCGAA AAAAAGAG
10722


7315
UCUTUUUUU UCCUAAAA
1304
UUUUAGGA CUGAUGAGGCCGUUAGGCCGAA AAAAAAGA
10723


7316
CUUUUUUUU CCUAAAAU
1305
AUUUUAGG CUGAUGAGGCCGUUAGGCCGAA AAAAAAAG
10724


7317
UUUUUUUUC CUAAAAUA
1306
UAUUUUAG CUGAUGAGGCCGUUAGGCCGAA AAAAAAAA
10725


7320
UUUUUCCUA AAAUAAAC
1307
GUUUAUUU CUGAUGAGGCCGUUAGGCCGAA AGGAAAAA
10726


7325
CCUAAAAUA AACUCAAA
1308
UUUGAGUU CUGAUGAGGCCGUUAGGCCGAA AUUUUAGG
10727


7330
AAUAAACUC AAAUUUAU
1309
AUAAAUUU CUGAUGAGGCCGUUAGGCCGAA AGUUUAUU
10728


7335
ACUCAAAUU UAUCCUUG
1310
CAAGGAUA CUGAUGAGGCCGUUAGGCCGAA AUUUGAGU
10729


7336
CUCAAAUUU AUCCUUGU
1311
ACAAGGAU CUGAUGAGGCCGUUAGGCCGAA AAUUUGAG
10730


7337
UCAAAUUUA UCCUUGUU
1312
AACAAGGA CUGAUGAGGCCGUUAGGCCGAA AAAUUUGA
10731


7339
AAAUUUAUC CUUGUUUA
1313
UAAACAAG CUGAUGAGGCCGUUAGGCCGAA AUAAAUUU
10732


7342
UUUAUCCUU GUUUAGAG
1314
CUCUAAAC CUGAUGAGGCCGUUAGGCCGAA AGGAUAAA
10733


7345
AUCCUUGUU UAGAGCAG
1315
CUGCUCUA CUGAUGAGGCCGUUAGGCCGAA ACAAGGAU
10734


7346
UCCUUGUUU AGAGCAGA
1316
UCUGCUCU CUGAUGAGGCCGUUAGGCCGAA AACAAGGA
10735


7347
CCUUGUUUA GAGCAGAG
1317
CUCUGCUC CUGAUGAGGCCGUUAGGCCGAA AAACAAGG
10736


7362
AGAAAAAUU AAGAAAAA
1318
UUUUUCUU CUGAUGAGGCCGUUAGGCCGAA AUUUUUCU
10737


7363
GAAAAAUUA AGAAAAAC
1319
GUUUUUCU CUGAUGAGGCCGUUAGGCCGAA AAUUUUUC
10738


7373
GAAAAACUU UGAAAUGG
1320
CCAUUUCA CUGAUGAGGCCGUUAGGCCGAA AGUUUUUC
10739


7374
AAAAACUUU GAAAUGGU
1321
ACCAUUUC CUGAUGAGGCCGUUAGGCCGAA AAGUUUUU
10740


7383
GAAAUGGUC UCAAAAAA
1322
UUUUUUGA CUGAUGAGGCCGUUAGGCCGAA ACCAUUUC
10741


7385
AAUGGUCUC AAAAAAUU
1323
AAUUUUUU CUGAUGAGGCCGUUAGGCCGAA AGACCAUU
10742


7393
CAAAAAAUU GCUAAAUA
1324
UAUUUAGC CUGAUGAGGCCGUUAGGCCGAA AUUUUUUG
10743


7397
AAAUUGCUA AAUAUUUU
1325
AAAAUAUU CUGAUGAGGCCGUUAGGCCGAA AGCAAUUU
10744


7401
UGCUAAAUA UUUUCAAU
1326
AUUGAAAA CUGAUGAGGCCGUUAGGCCGAA AUUUAGCA
10745


7403
CUAAAUAUU UUCAAUGG
1327
CCAUUGAA CUGAUGAGGCCGUUAGGCCGAA AUAUUUAG
10746


7404
UAAAUAUUU UCAAUGGA
1328
UCCAUUGA CUGAUGAGGCCGUUAGGCCGAA AAUAUUUA
10747


7405
AAAUAUUUU CAAUGGAA
1329
UUCCAUUG CUGAUGAGGCCGUUAGGCCGAA AAAUAUUU
10748


7406
AAUAUUUUC AAUGGAAA
1330
UUUCCAUU CUGAUGAGGCCGUUAGGCCGAA AAAAUAUU
10749


7418
GGAAAACUA AAUGUUAG
1331
CUAACAUU CUGAUGAGGCCGUUAGGCCGAA AGUUUUCC
10750


7424
CUAAAUGUU AGUUUAGC
1332
GCUAAACU CUGAUGAGGCCGUUAGGCCGAA ACAUUUAG
10751


7425
UAAAUGUUA GUUUAGCU
1333
AGCUAAAC CUGAUGAGGCCGUUAGGCCGAA AACAUUUA
10752


7428
AUGUUAGUU UAGCUGAU
1334
AUCAGCUA CUGAUGAGGCCGUUAGGCCGAA ACUAACAU
10753


7429
UGUUAGUUU AGCUGAUU
1335
AAUCAGCU CUGAUGAGGCCGUUAGGCCGAA AACUAACA
10754


7430
GUUAGUUUA GCUGAUUG
1336
CAAUCAGC CUGAUGAGGCCGUUAGGCCGAA AAACUAAC
10755


7437
UAGCUGAUU GUAUGGGG
1337
CCCCAUAC CUGAUGAGGCCGUUAGGCCGAA AUCAGCUA
10756


7440
CUGAUUGUA UGGGGUUU
1338
AAACCCCA CUGAUGAGGCCGUUAGGCCGAA ACAAUCAG
10757


7447
UAUGGGGUU UUCGAACC
1339
GGUUCGAA CUGAUGAGGCCGUUAGGCCGAA ACCCCAUA
10758


7448
AUGGGGUUU UCGAACCU
1340
AGGUUCGA CUGAUGAGGCCGUUAGGCCGAA AACCCCAU
10759


7449
UGGGGUUUU CGAACCUU
1341
AAGGUUCG CUGAUGAGGCCGUUAGGCCGAA AAACCCCA
10760


7450
GGGGUUUUC GAACCUUU
1342
AAAGGUUC CUGAUGAGGCCGUUAGGCCGAA AAAACCCC
10761


7457
UCGAACCUU UCACUUUU
1343
AAAAGUGA CUGAUGAGGCCGUUAGGCCGAA AGGUUCGA
10762


7458
CGAACCUUU CACUUUUU
1344
AAAAAGUG CUGAUGAGGCCGUUAGGCCGAA AAGGUUCG
10763


7459
GAACCUUUC ACUUUUUG
1345
CAAAAAGU CUGAUGAGGCCGUUAGGCCGAA AAAGGUUC
10764


7463
CUUUCACUU UUUGUUUG
1346
CAAACAAA CUGAUGAGGCCGUUAGGCCGAA AGUGAAAG
10765


7464
UUUCACUUU UUGUUUGU
1347
ACAAACAA CUGAUGAGGCCGUUAGGCCGAA AAGUGAAA
10766


7465
UUCACUUUU UGUUUGUU
1348
AACAAACA CUGAUGAGGCCGUUAGGCCGAA AAAGUGAA
10767


7466
UCACUUUUU GUUUGUUU
1349
AAACAAAC CUGAUGAGGCCGUUAGGCCGAA AAAAGUGA
10768


7469
CUUUUUGUU UGUUUUAC
1350
GUAAAACA CUGAUGAGGCCGUUAGGCCGAA ACAAAAAG
10769


7470
UUUUUGUUU GUUUUACC
1351
GGUAAAAC CUGAUGAGGCCGUUAGGCCGAA AACAAAAA
10770


7473
UUGUUUGUU UUACCUAU
1352
AUAGGUAA CUGAUGAGGCCGUUAGGCCGAA ACAAACAA
10771


7474
UGUUUGUUU UACCUAUU
1353
AAUAGGUA CUGAUGAGGCCGUUAGGCCGAA AACAAACA
10772


7475
UUUUGUUUU ACCUAUUU
1354
AAAUAGGU CUGAUGAGGCCGUUAGGCCGAA AAACAAAC
10773


7476
UUUGUUUUA CCUAUUUC
1355
GAAAUAGG CUGAUGAGGCCGUUAGGCCGAA AAAACAAA
10774


7480
UUUUACCUA UUUCACAA
1356
UUGUGAAA CUGAUGAGGCCGUUAGGCCGAA AGGUAAAA
10775


7482
UUACCUAUU UCACAACU
1357
AGUUGUGA CUGAUGAGGCCGUUAGGCCGAA AUAGGUAA
10776


7483
UACCUAUUU CACAACUG
1358
CAGUUGUG CUGAUGAGGCCGUUAGGCCGAA AAUAGGUA
10777


7484
ACCUAUUUC ACAACUGU
1359
ACAGUUGU CUGAUGAGGCCGUUAGGCCGAA AAAUAGGU
10778


7495
AACUGUGUA AAUUGCCA
1360
UGGCAAUU CUGAUGAGGCCGUUAGGCCGAA ACACAGUU
10779


7499
GUGUAAAUU GCCAAUAA
1361
UUAUUGGC CUGAUGAGGCCGUUAGGCCGAA AUUUACAC
10780


7506
UUGCCAAUA AUUCCUGU
1362
ACAGGAAU CUGAUGAGGCCGUUAGGCCGAA AUUGGCAA
10781


7509
CCAAUAUUU CCUGUCCA
1363
UGGACAGG CUGAUGAGGCCGUUAGGCCGAA AUUAUUGG
10782


7510
CAAUAAUUC CUGUCCAU
1364
AUGGACAG CUGAUGAGGCCGUUAGGCCGAA AAUUAUUG
10783


7515
AUUCCUGUC CAUGAAAA
1365
UUUUCAUG CUGAUGAGGCCGUUAGGCCGAA ACAGGAAU
10784


7531
AUGCAAAUU AUCCAGUG
1366
CACUGGAU CUGAUGAGGCCGUUAGGCCGAA AUUUGCAU
10785


7532
UGCAAAUUA UCCAGUGU
1367
ACACUGGA CUGAUGAGGCCGUUAGGCCGAA AAUUUGCA
10786


7534
CAAAUUAUC CAGUGUAG
1368
CUACACUG CUGAUGAGGCCGUUAGGCCGAA AUAAUUUG
10787


7541
UCCAGUGUA GAUAUAUU
1369
AAUAUAUC CUGAUGAGGCCGUUAGGCCGAA ACACUGGA
10788


7545
GUGUAGAUA UAUUUGAC
1370
GUCAAAUA CUGAUGAGGCCGUUAGGCCGAA AUCUACAC
10789


7547
GUAGAUAUA UUUGACCA
1371
UGGUCAAA CUGAUGAGGCCGUUAGGCCGAA AUAUCUAC
10790


7549
AGAUAUAUU UGACCAUC
1372
GAUGGUCA CUGAUGAGGCCGUUAGGCCGAA AUAUAUCU
10791


7550
GAUAUAUUU GACCAUCA
1373
UGAUGGUC CUGAUGAGGCCGUUAGGCCGAA AAUAUAUC
10792


7557
UUGACCAUC ACCCUAUG
1374
CAUAGGGU CUGAUGAGGCCGUUAGGCCGAA AUGGUCAA
10793


7563
AUCACCCUA UGGAUAUU
1375
AAUAUCCA CUGAUGAGGCCGUUAGGCCGAA AGGGUGAU
10794


7569
CUAUGGAUA UUGOCUAG
1376
CUAGCCAA CUGAUGAGGCCGUUAGGCCGAA AUCCAUAG
10795


7571
AUGGAUAUU GGCUAGUU
1377
AACUAGCC CUGAUGAGGCCGUUAGGCCGAA AUAUCCAU
10796


7576
UAUUGGCUA GUUUUGCC
1378
GGCAAAAC CUGAUGAGGCCGUUAGGCCGAA AGCCAAUA
10797


7579
UGGCUAGUU UUGCCUUU
1379
AAAGGCAA CUGAUGAGGCCGUUAGGCCGAA ACUAGCCA
10798


7580
GGCUAGUUU UGCCUUUA
1380
UAAAGGCA CUGAUGAGGCCGUUAGGCCGAA AACUAGCC
10799


7581
GCUAGUUUU GCCUUUAU
1381
AUAAAGGC CUGAUGAGGCCGUUAGGCCGAA AAACUAGC
10800


7586
UUUUGCCUU UAUUAAGC
1382
GCUUAAUA CUGAUGAGGCCGUUAGGCCGAA AGGCAAAA
10801


7587
UUUGCCUUU AUUAAGCA
1383
UGCUUAAU CUGAUGAGGCCGUUAGGCCGAA AAGGCAAA
10802


7588
UUGCCUUUA UUAAGCAA
1384
UUGCUUAA CUGAUGAGGCCGUUAGGCCGAA AAAGGCAA
10803


7590
GCCUUUAUU AAGCAAAU
1385
AUUUGCUU CUGAUGAGGCCGUUAGGCCGAA AUAAAGGC
10804


7591
CCUUUAUUA AGCAAAUU
1386
AAUUUGCU CUGAUGAGGCCGUUAGGCCGAA AAUAAAGG
10805


7599
AAGCAAAUU CAUUUCAG
1387
CUGAAAUG CUGAUGAGGCCGUUAGGCCGAA AUUUGCUU
10806


7600
AGCAAAUUC AUUUCAGC
1388
GCUGAAAU CUGAUGAGGCCGUUAGGCCGAA AAUUUGCU
10807


7603
AAAUUCAUU UCAGCCUG
1389
CAGGCUGA CUGAUGAGGCCGUUAGGCCGAA AUGAAUUU
10808


7604
AAUUCAUUU CAGCCUGA
1390
UCAGGCUG CUGAUGAGGCCGUUAGGCCGAA AAUGAAUU
10809


7605
AUUCAUUUC AGCCUGAA
1391
UUCAGGCU CUGAUGAGGCCGUUAGGCCGAA AAAUGAAU
10810


7617
CUGAAUGUC UGCCUAUA
1392
UAUAGGCA CUGAUGAGGCCGUUAGGCCGAA ACAUUCAG
10811


7623
GUCUGCCUA UAUAUUCU
1393
AGAAUAUA CUGAUGAGGCCGUUAGGCCGAA AGGCAGAC
10812


7625
CUGCCUAUA UAUUCUCU
1394
AGAGAAUA CUGAUGAGGCCGUUAGGCCGAA AUAGGCAG
10813


7627
GCCUAUAUA UUCUCUGC
1395
GCAGAGAA CUGAUGAGGCCGUUAGGCCGAA AUAUAGGC
10814


7629
CUAUAUAUU CUCUGCUC
1396
GAGCAGAG CUGAUGAGGCCGUUAGGCCGAA AUAUAUAG
10815


7630
UAUAUAUUC UCUGCUCU
1397
AGAGCAGA CUGAUGAGGCCGUUAGGCCGAA AAUAUAUA
10816


7632
UAUAUUCUC UGCUCUUU
1398
AAAGAGCA CUGAUGAGGCCGUUAGGCCGAA AGAAUAUA
10817


7637
UCUCUGCUC UUUGUAUU
1399
AAUACAAA CUGAUGAGGCCGUUAGGCCGAA AGCAGAGA
10818


7639
UCUGCUCUU UGUAUUCU
1400
AGAAUACA CUGAUGAGGCCGUUAGGCCGAA AGAGCAGA
10819


7640
CUGCUCUUU GUAUUCUC
1401
GAGAAUAC CUGAUGAGGCCGUUAGGCCGAA AAGAGCAG
10820


7643
CUCUUUGUA UUCUCCUU
1402
AAGGAGAA CUGAUGAGGCCGUUAGGCCGAA ACAAAGAG
10821


7645
CUUUGUAUU CUCCUUUG
1403
CAAAGGAG CUGAUGAGGCCGUUAGGCCGAA AUACAAAG
10822


7646
UUUGUAUUC UCCUUUGA
1404
UCAAAGGA CUGAUGAGGCCGUUAGGCCGAA AAUACAAA
10823


7648
UGUAUUCUC CUUUGAAC
1405
GUUCAAAG CUGAUGAGGCCGUUAGGCCGAA AGAAUACA
10824


7651
AUUCUCCUU UGAACCCG
1406
CGGGUUCA CUGAUGAGGCCGUUAGGCCGAA AGGAGAAU
10825


7652
UUCUCCUUU GAACCCGU
1407
ACGGGUUC CUGAUGAGGCCGUUAGGCCGAA AAGGAGAA
10826


7661
GAACCCGUU AAAACAUC
1408
GAUGUUUU CUGAUGAGGCCGUUAGGCCGAA ACGGGUUC
10827


7662
AACCCGUUA AAACAUCC
1409
GGAUGUUU CUGAUGAGGCCGUUAGGCCGAA AACGGGUU
10828


7669
UAAAACAUC CUGUGGCA
1410
UGCCACAG CUGAUGAGGCCGUUAGGCCGAA AUGUUUUA
10829






Where “X” represents stem II region of a HH ribozyme (Hertel et al., 1992 Nucleic Acids Res. 20 3252). The length of stem II may be 2 base-pairs.




Underlined region can be any X sequence or linker, as described herein.








[0342]

6






TABLE III










Human fltl VEGF Receptor-Hairpin Ribozyme and Substrate sequence















Seq

Seq





ID

ID


Pos
Substrate
No
Hp Ribozyme Sequence
No















16
CCUCUCG GCU CCUCCCCG
1411
CGGGGAGG AGAA GAGAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10830






39
GGCGGCG GCU CGGAGCGC
1412
CCGCUCCG AGAA GCCGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10831





180
GACGACG GAC UCUGGCGG
1413
CCCCCAGA AGAA GUCCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10832





190
UCUGGCG GCC GGGUCGUU
1414
AACGACCC AGAA GCCAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10833





278
GGGUCCU GCU GUGCGCGC
1415
GCGCGCAC AGAA GGACCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10834





290
GCGCGCU GCU CAGCUGUC
1416
GACAUCUG AGAA GCGCGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10835





295
CUCCUCA GCU GUCUGCUU
1417
AAGCAGAC AGAA GAGCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10836





298
CUCAGCU GUC UGCUUCUC
1418
GAGAAGCA AGAA GCUGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10837





302
GCUGUCU GCU UCUCACAG
1419
CUGUGAGA AGAA GACAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10838





420
GGAAGCA GCC CAUAAAUG
1420
CAUUUAUG AGAA GCUUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10839





486
UAAAUCU GCC UGUGGAAG
1421
CUUCCACA AGAA GAUUUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10840





537
GAACACA GCU CAAGCAAA
1422
UUUGCUUG AGAA GUGUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10841





565
UUCUACA GCU GCAAAUAU
1423
AUAUUUGC AGAA GUAGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10842





721
AUUCCCU CCC GGGUUACG
1424
CGUAACCC AGAA GGGAAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10843





786
GAUCCCU GAU GGAAAACG
1425
CGUUUUCC AGAA GGGAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10844





863
GGCUUCU GAC CUGUGAAG
1426
CUUCACAG AGAA GAAGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10845





1056
UUACCCU GAU GAAAAAAA
1427
UUUUUUUC AGAA GGGUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10846





1301
GCAAGCG GUC UUACCGGC
1428
GCCGGUAA AGAA GCUUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10847





1310
CUUACCG GCU CUCUAUGA
1429
UCAUAGAG AGAA GGUAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10848





1389
GAAAUCU GCU CGCUAUUU
1430
AAAUAGCG AGAA GAUUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10849





1535
AACCCCA GAU UUACGAAA
1431
UUUCGUAA AGAA GGGGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10850





1566
GUUUCCA GAC CCGGCUCU
1432
AGAGCCGG AGAA GGAAAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10851





1572
AGACCCG GCU CUCUACCC
1433
GGGUAGAG AGAA GGGUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10852





1604
AAAUCCU GAC UUGUACCG
1434
CGGUACAA AGAA GGAUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10853





1824
UGUGGCU GAC UCUAGAAU
1435
AUUCUAGA AGAA GCCACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10854





1908
UAUCACA GAU GUGCCAAA
1436
UUUGGCAC AGAA GUGAUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10855





1949
AAAUGCC GAC GGAAGGAG
1437
CUCCUUCC AGAA GCAUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10856





1973
UGAAACU GUC UUGCACAG
1438
CUGUGCAA AGAA GUUUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10857





2275
AUCACCA GUU CCACCACU
1439
AGUGGUGG AGAA GCUGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10858





2321
AGCCUCA GAU CACUUGGU
1440
ACCAAGUG AGAA GAGGCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10859





2396
GCACGCU GUU UAUUGAAA
1441
UUUCAAUA AGAA GCGUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10860





2490
CCUCACU GUU CAAGGAAC
1442
GUUCCUUG AGAA GUGAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10861





2525
UGGAGCU GAU CACUCUAA
1443
UUAGAGUG AGAA GCUCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10862





2625
AAAGACU GAC UACCUAUC
1444
GAUAGGUA AGAA GUCUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10863





2652
GGACCCA GAU GAAGUUCC
1445
GGAACUUC AGAA GGGUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10864





2684
GUGAGCG GCU CCCUUAUG
1446
CAUAAGGG AGAA GCUCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10865





2816
CGUGCCG GAC UGUGGCUG
1447
CAGCCACA AGAA GGCACG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10866





2873
AAGCUCU GAU GACUGAGC
1448
GCUCAGUC AGAA GAGCUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10867





2930
UUAACCU GCU GGGAGCCU
1449
AGGCUCCC AGAA GGUUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10868





2963
GGCCUCU GAU GGUGAUUG
1450
CAAUCACC AGAA GAGGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10869





3157
AGCUCCG GCU UUCAGGAA
1451
UUCCUGAA AGAA GGAGCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10870





3207
GGAUUCU GAC GGUUUCUA
1452
UAGAAACC AGAA GAAUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10871





3211
UCUGACG GUU UCUACAAG
1453
CUUGUAGA AGAA GUCAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10872





3245
AAGAUCU GAU UUCUUACA
1454
UGUAAGAA AGAA GAUCUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10873





3256
UCUUACA GUU UUCAAGUG
1455
CACUUGAA AGAA GUAAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10874





3287
AGUUCCU GUC UUCCAGAA
1456
UUCUGGAA AGAA GGAACU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10875





3402
GAACCCC GAU UAUGUGAG
1457
CUCACAUA AGAA GGGUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10876





3580
UUUUGCA GUC GCCUGAGG
1458
CCUCAGGC AGAA GCAAAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10877





3641
UCUAUCA GAU CAUGCUGG
1459
CCAGCAUG AGAA GAUAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10878





3655
CUGGACU GCU GGCACAGA
1460
UCUGUGCC AGAA GUCCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10879





3810
AACUCCU GCC UUCUCUGA
1461
UCAGAGAA AGAA GGAGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10880





3846
UAUUUCA GCU CCGAAGUU
1462
AACUUCGG AGAA GAAAUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10881





3873
AAGCUCU GAU GAUGUCAG
1463
CUGACAUC AGAA GAGCUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10882





3995
GCACUCU GUU GGCCUCUC
1464
GAGAGGCC AGAA GAGUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10883





4100
CGGGGCU GUC UGAUGUCA
1465
UGACAUCA AGAA GCCCCG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10884





4104
GCUGUCU GAU GUCAGCAG
1466
CUGCUGAC AGAA GACAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10885





4120
AGGCCCA GUU UCUGCCAU
1467
AUGGCAGA AGAA GGGCCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10886





4135
CAUUCCA GCU GUGGGCAC
1468
GUGCCCAC AGAA GGAAUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10887





4210
GCGUGCU GCU CCCCGCCC
1469
GGGCGGGG AGAA GCACGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10888





4217
GCUCCCC GCC CCCAGACU
1470
AGUCUGGG AGAA GGGAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10889





4224
GCCCCCA GAC UACAACUC
1471
GAGUUGUA AGAA GGGGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10890





4382
GGAGCCA GCU GCUUUUUG
1472
CAAAAAGC AGAA GGCUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10891





4385
GCCAGCU GCU UUUUGUGA
1473
UCACAAAA AGAA GCUGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10892





4537
CUUCCCU GCU CCAACCCC
1474
GGGGUUGG AGAA GGGAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10893





4573
AGGACCA GUU UGAUUGAG
1475
CUCAAUCA AGAA GGUCCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10894





4594
CUGCACU GAU CACCCAAU
1476
AUUGGGUG AGAA GUGCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10895





4628
UGGGCCA CCC CUGCAGCC
1477
GGCUGCAG AGAA GGCCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10896





4636
CCCUGCA GCC CAAAACCC
1478
GGGUUUUG ACAA GCAGGG ACCAGACAAACACACGUUGUGGUACAUUACCUGGUA
10897





4866
CUUCCCA GCU CUGACCCU
1479
ACGGUCAG AGAA GGGAAG ACCACAGAAACACACQUUGUGGUACAUUACCUGGUA
10898





4871
CACCUCU CAC CCUUCUAC
1480
GUACAAGG AGAA GAGCUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10899





4905
AGGACCA GAU GGACAGCG
1481
CGCUGUCC AGAA GCUCCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10900





5233
UUAUUCU GUU UUCCACAG
1482
CUGUGCAA AGAA GAAUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10901





5281
AAAUGCA GUC CUGAGGAG
1483
CUCCUCAG AGAA GCAUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10902





5319
GAGGGCU GAU GGAGGAAA
1484
UUUCCUCC AGAA GCCCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10903





5358
AGACCCC GUC UCUAUACC
1485
GGUAUAGA AGAA GGGUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10904





5392
CAACACA GUU GGGACCCA
1486
UGGGUCCC AGAA GUGUUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10905





5563
UUCUCCA GUU GGGACUCA
1487
UGAGUCCC AGAA GGAGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10906





5622
UUCAACU GCU UUGAAACU
1488
AGUUUCAA AGAA GUUGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10907





5738
UGGCUCU GUU UGAUGCUA
1489
UAGCAUCA AGAA GAGCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10908





5838
UGGCUCU GUU UGAUGCUA
1489
UAGCAUCA AGAA GAGCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10908





5933
GAUUGCU GCU UCUUGGGG
1490
CCCCAAGA AGAA GCAAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10909





6022
UGCCUCU GUU CUUAUGUG
1491
CACAUAAG AGAA GAGGCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10910





6120
GGCAGCG GCU UCUGUGGA
1492
UCCACAAA AGAA GCUGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10911





6163
UGGGACA GUC CUCUCCAC
1493
GUGGAGAG AGAA GUCCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10912





6270
UGUGACA GCU GGCAAUUU
1494
AAAUUGCC AGAA GUCACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10913





6412
CUUAGCU GUU CAUGUCUU
1495
AAGACAUG AGAA GCUAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10914





6511
UUACUCA GCU CCUUCAAA
1496
UUUGAAGG AGAA GAGUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10915





6778
UGGAACA GUC UGGGUGGA
1497
UCCACCCA AGAA GUUCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10916





6826
CUUGUCA GUC CAAGAAGU
1498
ACUUCUUG AGAA GACAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10917





7245
GGCAACU GCU UUUAUGUU
1499
AACAUAAA AGAA GUUGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10918





7258
AUGUUCU GUC UCCUUCCA
1500
UGGAAGGA AGAA GAACAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10919





7433
UUUAGCU GAU UGUAUGGG
1501
CCCAUACA AGAA GCUAAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10920





7512
AAUUCCU GUC CAUGAAAA
1502
UUUUCAUG AGAA GGAAUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10921





7606
CAUUUCA CCC UGAAUGUC
1503
GACAUUCA AGAA GAAAUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10922





7618
AAUGUCU CCC UAUAUAUU
1504
AAUAUAUA AGAA GACAUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10923





7633
AUUCUCU GCU CUUUGUAU
1505
AUACAAAG AGAA GAGAAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10924










[0343]

7






TABLE IV










Human KDR VEGF Receptor-Hammerhead Ribozyme and Substrate Sequence














Seq ID

Seq ID


Pos
Substrate
No
HH Ribozyme Sequence
No















21
CUGGCCGUC GCCCUGUG
1506
CACAGGGC CUGAUGAGGCCGUUAGGCCGAA ACGGCCAG
10925






33
CUGUGGCUC UGCGUGGA
1507
UCCACGCA CUGAUGAGGCCGUUAGGCCGAA AGCCACAG
10926





56
GGCCGCCUC UGUGGGUU
1508
AACCCACA CUGAUGAGGCCGUUAGGCCGAA AGGCGGCC
10927





64
CUGUGGGUU UGCCUAGU
1509
ACUAGGCA CUGAUGAGGCCGUUAGGCCGAA ACCCACAG
10928





65
UGUGGGUUU GCCUAGUG
1510
CACUAGGC CUGAUGAGGCCGUUAGGCCGAA AACCCACA
10929





70
GUUUGCCUA GUGUUUCU
1511
AGAAACAC CUGAUGAGGCCGUUAGGCCGAA AGGCAAAC
10930





75
CCUAGUGUU UCUCUUGA
1512
UCAAGAGA CUGAUGAGGCCGUUAGGCCGAA ACACUAGG
10931





76
CUAGUGUUU CUCUUGAU
1513
AUCAAGAG CUGAUGAGGCCGUUAGGCCGAA AACACUAG
10932





77
UAGUGUUUC UCUUGAUC
1514
GAUCAAGA CUGAUGAGGCCGUUAGGCCGAA AAACACUA
10933





79
GUGUUUCUC UUGAUCUG
1515
CAGAUCAA CUGAUGAGGCCGUUAGGCCGAA AGAAACAC
10934





81
GUUUCUCUU GAUCUGCC
1516
GGCAGAUC CUGAUGAGGCCGUUAGGCCGAA AGAGAAAC
10935





85
CUCUUGAUC UGCCCAGG
1517
CCUGGGCA CUGAUGAGGCCGUUAGGCCGAA AUCAAGAG
10936





96
CCCAGGCUC AGCAUACA
1518
UGUAUGCU CUGAUGAGGCCGUUAGGCCGAA AGCCUGGG
10937





102
CUCAGCAUA CAAAAAGA
1519
UCUUUUUG CUGAUGAGGCCGUUAGGCCGAA AUGCUGAG
10938





114
AAAGACAUA CUUACAAU
1520
AUUGUAAG CUGAUGAGGCCGUUAGGCCGAA AUGUCUUU
10939





117
GACAUACUU ACAAUUAA
1521
UUAAUUGU CUGAUGAGGCCGUUAGGCCGAA AGUAUGUC
10940





118
ACAUACUUA CAAUUAAG
1522
CUUAAUUG CUGAUGAGGCCGUUAGGCCGAA AAGUAUGU
10941





123
CUUACAAUU AAGGCUAA
1523
UUAGCCUU CUGAUGAGGCCGUUAGGCCGAA AUUGUAAG
10942





124
UUACAAUUA AGGCUAAU
1524
AUUAGCCU CUGAUGAGGCCGUUAGGCCGAA AAUUGUAA
10943





130
UUAAGGCUA AUACAACU
1525
AGUUGUAU CUGAUGAGGCCGUUAGGCCGAA AGCCUUAA
10944





133
AGGCUAAUA CAACUCUU
1526
AAGAGUUG CUGAUGAGGCCGUUAGGCCGAA AUUAGCCU
10945





139
AUACAACUC UUCAAAUU
1527
AAUUUGAA CUGAUGAGGCCGUUAGGCCGAA AGUUGUAU
10946





141
ACAACUCUU CAAAUUAC
1528
GUAAUUUG CUGAUGAGGCCGUUAGGCCGAA AGAGUUGU
10947





142
CAACUCUUC AAAUUACU
1529
AGUAAUUU CUGAUGAGGCCGUUAGGCCGAA AAGAGUUG
10948





147
CUUCAAAUU ACUUGCAG
1530
CUGCAAGU CUGAUGAGGCCGUUAGGCCGAA AUUUGAAG
10949





148
UUCAAAUUA CUUGCAGG
1531
CCUGCAAG CUGAUGAGGCCGUUAGGCCGAA AAUUUGAA
10950





151
AAAUUACUU GCAGGGGA
1532
UCCCCUGC CUGAUGAGGCCGUUAGGCCGAA AGUAAUUU
10951





170
GAGGGACUU GGACUGGC
1533
GCCAGUCC CUGAUGAGGCCGUUAGGCCGAA AGUCCCUC
10952





180
GACUGGCUU UGGCCCAA
1534
UUGGGCCA CUGAUGAGGCCGUUAGGCCGAA AGCCAGUC
10953





181
ACUGGCUUU GGCCCAAU
1535
AUUGGGCC CUGAUGAGGCCGUUAGGCCGAA AAGCCAGU
10954





190
GGCCCAAUA AUCAGAGU
1536
ACUCUGAU CUGAUGAGGCCGUUAGGCCGAA AUUGGGCC
10955





193
CCAAUAAUC AGAGUGGC
1537
GCCACUCU CUGAUGAGGCCGUUAGGCCGAA AUUAUUGG
10956





243
GAUGGCCUC UUCUGUAA
1538
UUACAGAA CUGAUGAGGCCGUUAGGCCGAA AGGCCAUC
10957





245
UGGCCUCUU CUGUAAGA
1539
UCUUACAG CUGAUGAGGCCGUUAGGCCGAA AGAGGCCA
10958





246
GGCCUCUUC UGUAAGAC
1540
GUCUUACA CUGAUGAGGCCGUUAGGCCGAA AAGAGGCC
10959





250
UCUUCUGUA AGACACUC
1541
GAGUGUCU CUGAUGAGGCCGUUAGGCCGAA ACAGAAGA
10960





258
AAGACACUC ACAAUUCC
1542
GGAAUUGU CUGAUGAGGCCGUUAGGCCGAA AGUGUCUU
10961





264
CUCACAAUU CCAAAAGU
1543
ACUUUUGG CUGAUGAGGCCGUUAGGCCGAA AUUGUGAG
10962





265
UCACAAUUC CAAAAGUG
1544
CACUUUUG CUGAUGAGGCCGUUAGGCCGAA AAUUGUGA
10963





276
AAAGUGAUC GGAAAUGA
1545
UCAUUUCC CUGAUGAGGCCGUUAGGCCGAA AUCACUUG
10964





296
UGGAGCCUA CAAGUGCU
1546
AGCACUUG CUGAUGAGGCCGUUAGGCCGAA AGGCUCCA
10965





305
CAAGUGCUU CUACCGGG
1547
CCCGGUAG CUGAUGAGGCCGUUAGGCCGAA AGCACUUG
10966





306
AAGUGCUUC UACCGGGA
1548
UCCCGGUA CUGAUGAGGCCGUUAGGCCGAA AAGCACUU
10967





308
GUGCUUCUA CCGGGAAA
1549
UUUCCCGG CUGAUGAGGCCGUUAGGCCGAA AGAAGCAC
10968





323
AACUGACUU GGCCUCGG
1550
CCGAGGCC CUGAUGAGGCCGUUAGGCCGAA AGUCAGUU
10969





329
CUUGGCCUC GGUCAUUU
1551
AAAUGACC CUGAUGAGGCCGUUAGGCCGAA AGGCCAAG
10970





333
GCCUCGGUC AUUUAUGU
1552
ACAUAAAU CUGAUGAGGCCGUUAGGCCGAA ACCGAGGC
10971





336
UCGGUCAUU UAUGUCUA
1553
UAGACAUA CUGAUGAGGCCGUUAGGCCGAA AUGACCGA
10972





337
CGGUCAUUU AUGUCUAU
1554
AUAGACAU CUGAUGAGGCCGUUAGGCCGAA AAUGACCG
10973





338
GGUCAUUUA UGUCUAUG
1555
CAUAGACA CUGAUGAGGCCGUUAGGCCGAA AAAUGACC
10974





342
AUUUAUGUC UAUGUUCA
1556
UGAACAUA CUGAUGAGGCCGUUAGGCCGAA ACAUAAAU
10975





344
UUAUGUCUA UGUUCAAG
1557
CUUGAACA CUGAUGAGGCCGUUAGGCCGAA AGACAUAA
10976





348
GUCUAUGUU CAAGAUUA
1558
UAAUCUUG CUGAUGAGGCCGUUAGGCCGAA ACAUAGAC
10977





349
UCUAUGUUC AAGAUUAC
1559
GUAAUCUU CUGAUGAGGCCGUUAGGCCGAA AACAUAGA
10978





355
UUCAAGAUU ACAGAUCU
1560
AGAUCUGU CUGAUGAGGCCGUUAGGCCGAA AUCUUGAA
10979





356
UCAAGAUUA CAGAUCUC
1561
GAGAUCUG CUGAUGAGGCCGUUAGGCCGAA AAUCUUGA
10980





362
UUACAGAUC UCCAUUUA
1562
UAAAUGGA CUGAUGAGGCCGUUAGGCCGAA AUCUGUAA
10981





364
ACAGAUCUC CAUUUAUU
1563
AAUAAAUG CUGAUGAGGCCGUUAGGCCGAA AGAUCUGU
10982





368
AUCUCCAUU UAUUGCUU
1564
AAGCAAUA CUGAUGAGGCCGUUAGGCCGAA AUGGAGAU
10983





369
UCUCCAUUU AUUGCUUC
1565
GAAGCAAU CUGAUGAGGCCGUUAGGCCGAA AAUGGAGA
10984





370
CUCCAUUUA UUGCUUCU
1566
AGAAGCAA CUGAUGAGGCCGUUAGGCCGAA AAAUGGAG
10985





372
CCAUUUAUU GCUUCUGU
1567
ACAGAAGC CUGAUGAGGCCGUUAGGCCGAA AUAAAUGG
10986





376
UUAUUGCUU CUGUUAGU
1568
ACUAACAG CUGAUGAGGCCGUUAGGCCGAA AGCAAUAA
10987





377
UAUUGCUUC UGUUAGUG
1569
CACUAACA CUGAUGAGGCCGUUAGGCCGAA AAGCAAUA
10988





381
GCUUCUGUU AGUGACCA
1570
UGGUCACU CUGAUGAGGCCGUUAGGCCGAA ACAGAAGC
10989





382
CUUCUGUUA GUGACCAA
1571
UUGGUCAC CUGAUGAGGCCGUUAGGCCGAA AACAGAAG
10990





399
CAUGGAGUC GUGUACAU
1572
AUGUACAC CUGAUGAGGCCGUUAGGCCGAA ACUCCAUG
10991





404
AGUCGUGUA CAUUACUG
1573
CAGUAAUG CUGAUGAGGCCGUUAGGCCGAA ACACGACU
10992





408
GUGUACAUU ACUGAGAA
1574
UUCUCAGU CUGAUGAGGCCGUUAGGCCGAA AUGUACAC
10993





409
UGUACAUUA CUGAGAAC
1575
GUUCUCAG CUGAUGAGGCCGUUAGGCCGAA AAUGUACA
10994





438
GUGGUGAUU CCAUGUCU
1576
AGACAUGG CUGAUGAGGCCGUUAGGCCGAA AUCACCAC
10995





439
UGGUGAUUC CAUGUCUC
1577
GAGACAUG CUGAUGAGGCCGUUAGGCCGAA AAUCACCA
10996





445
UUCCAUGUC UCGGGUCC
1578
GGACCCGA CUGAUGAGGCCGUUAGGCCGAA ACAUGGAA
10997





447
CCAUGUCUC GGGUCCAU
1579
AUGGACCC CUGAUGAGGCCGUUAGGCCGAA AGACAUGG
10998





452
UCUCGGGUC CAUUUCAA
1580
UUGAAAUG CUGAUGAGGCCGUUAGGCCGAA ACCCGAGA
10999





456
GGGUCCAUU UCAAAUCU
1581
AGAUUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGACCC
11000





457
GGUCCAUUU CAAAUCUC
1582
GAGAUUUG CUGAUGAGGCCGUUAGGCCGAA AAUGGACC
11001





458
GUCCAUUUC AAAUCUCA
1583
UGAGAUUU CUGAUGAGGCCGUUAGGCCGAA AAAUGGAC
11002





463
UUUCAAAUC UCAACGUG
1584
CACGUUGA CUGAUGAGGCCGUUAGGCCGAA AUUUGAAA
11003





465
UCAAAUCUC AACGUGUC
1585
GACACGUU CUGAUGAGGCCGUUAGGCCGAA AGAUUUGA
11004





473
CAACGUGUC ACUUUGUG
1586
CACAAAGU CUGAUGAGGCCGUUAGGCCGAA ACACGUUG
11005





477
GUGUCACUU UGUGCAAG
1587
CUUGCACA CUGAUGAGGCCGUUAGGCCGAA AGUGACAC
11006





478
UGUCACUUU GUGCAAGA
1588
UCUUGCAC CUGAUGAGGCCGUUAGGCCGAA AAGUGACA
11007





488
UGCAAGAUA CCCAGAAA
1589
UUUCUGGG CUGAUGAGGCCGUUAGGCCGAA AUCUUGCA
11008





503
AAAGAGAUU UGUUCCUG
1590
CAGGAACA CUGAUGAGGCCGUUAGGCCGAA AUCUCUUU
11009





504
AAGAGAUUU GUUCCUGA
1591
UCAGGAAC CUGAUGAGGCCGUUAGGCCGAA AAUCUCUU
11010





507
AGAUUUGUU CCUGAUGG
1592
CCAUCAGG CUGAUGAGGCCGUUAGGCCGAA ACAAAUCU
11011





508
GAUUUGUUC CUGAUGGU
1593
ACCAUCAG CUGAUGAGGCCGUUAGGCCGAA AACAAAUC
11012





517
CUGAUGGUA ACAGAAUU
1594
AAUUCUGU CUGAUGAGGCCGUUAGGCCGAA ACCAUCAG
11013





525
AACAGAAUU UCCUGGGA
1595
UCCCAGGA CUGAUGAGGCCGUUAGGCCGAA AUUCUGUU
11014





526
ACAGAAUUU CCUGGGAC
1596
GUCCCAGG CUGAUGAGGCCGUUAGGCCGAA AAUUCUGU
11015





527
CAGAAUUUC CUGGGACA
1597
UGUCCCAG CUGAUGAGGCCGUUAGGCCGAA AAAUUCUG
11016





548
GAAGGGCUU UACUAUUC
1598
GAAUAGUA CUGAUGAGGCCGUUAGGCCGAA AGCCCUUC
11017





549
AAGGGCUUU ACUAUUCC
1599
GGAAUAGU CUGAUGAGGCCGUUAGGCCGAA AAGCCCUU
11018





550
AGGGCUUUA CUAUUCCC
1600
GGGAAUAG CUGAUGAGGCCGUUAGGCCGAA AAAGCCCU
11019





553
GCUUUACUA UUCCCAGC
1601
GCUGGGAA CUGAUGAGGCCGUUAGGCCGAA AGUAAAGC
11020





555
UUUACUAUU CCCAGCUA
1602
UAGCUGGG CUGAUGAGGCCGUUAGGCCGAA AUAGUAAA
11021





556
UUACUAUUC CCAGCUAC
1603
GUAGCUGG CUGAUGAGGCCGUUAGGCCGAA AAUAGUAA
11022





563
UCCCAGCUA CAUGAUCA
1604
UGAUCAUG CUGAUGAGGCCGUUAGGCCGAA AGCUGGGA
11023





570
UACAUGAUC AGCUAUGC
1605
GCAUAGCU CUGAUGAGGCCGUUAGGCCGAA AUCAUGUA
11024





575
GAUCAGCUA UGCUGGCA
1606
UGCCAGCA CUGAUGAGGCCGUUAGGCCGAA AGCUGAUC
11025





586
GGCAUGGUC UUCUGUGA
1607
UCACAGAA CUGAUGAGGCCGUUAGGCCGAA ACCAUGCC
11026





590
CAUGGUCUU CUGUGAAG
1608
CUUCACAG CUGAUGAGGCCGUUAGGCCGAA AGACCAUG
11027





591
AUGGUCUUC UGUGAAGC
1609
GCUUCACA CUGAUGAGGCCGUUAGGCCGAA AAGACCAU
11028





606
GCAAAAAUU AAUGAUGA
1610
UCAUCAUU CUGAUGAGGCCGUUAGGCCGAA AUUUUUGC
11029





607
CAAAAAUUA AUGAUGAA
1611
UUCAUCAU CUGAUGAGGCCGUUAGGCCGAA AAUUUUUG
11030





619
AUGAAAGUU ACCAGUCU
1612
AGACUGGU CUGAUGAGGCCGUUAGGCCGAA ACUUUCAU
11031





620
UGAAAGUUA CCAGUCUA
1613
UAGACUGG CUGAUGAGGCCGUUAGGCCGAA AACUUUCA
11032





626
UUACCAGUC UAUUAUGU
1614
ACAUAAUA CUGAUGAGGCCGUUAGGCCGAA ACUGGUAA
11033





628
ACCAGUCUA UUAUGUAC
1615
GUACAUAA CUGAUGAGGCCGUUAGGCCGAA AGACUGGU
11034





630
CAGUCUAUU AUGUACAU
1616
AUGUACAU CUGAUGAGGCCGUUAGGCCGAA AUAGACUG
11035





631
AGUCUAUUA UGUACAUA
1617
UAUGUACA CUGAUGAGGCCGUUAGGCCGAA AAUAGACU
11036





635
UAUUAUGUA CAUAGUUG
1618
CAACUAUG CUGAUGAGGCCGUUAGGCCGAA ACAUAAUA
11037





639
AUGUACAUA GUUGUCGU
1619
ACGACAAC CUGAUGAGGCCGUUAGGCCGAA AUGUACAU
11038





642
UACAUAGUU GUCGUUGU
1620
ACAACGAC CUGAUGAGGCCGUUAGGCCGAA ACUAUGUA
11039





645
AUAGUUGUC GUUGUAGG
1621
CCUACAAC CUGAUGAGGCCGUUAGGCCGAA ACAACUAU
11040





648
GUUGUCGUU GUAGGGUA
1622
UACCCUAC CUGAUGAGGCCGUUAGGCCGAA ACGACAAC
11041





651
GUCGUUGUA GGGUAUAG
1623
CUAUACCC CUGAUGAGGCCGUUAGGCCGAA ACAACGAC
11042





656
UGUAGGGUA UAGGAUUU
1624
AAAUCCUA CUGAUGAGGCCGUUAGGCCGAA ACCCUACA
11043





658
UAGGGUAUA GGAUUUAU
1625
AUAAAUCC CUGAUGAGGCCGUUAGGCCGAA AUACCCUA
11044





663
UAUAGGAUU UAUGAUGU
1626
ACAUCAUA CUGAUGAGGCCGUUAGGCCGAA AUCCUAUA
11045





664
AUAGGAUUU AUGAUGUG
1627
CACAUCAU CUGAUGAGGCCGUUAGGCCGAA AAUCCUAU
11046





665
UAGGAUUUA UGAUGUGG
1628
CCACAUCA CUGAUGAGGCCGUUAGGCCGAA AAAUCCUA
11047





675
GAUGUGGUU CUGAGUCC
1629
GGACUCAG CUGAUGAGGCCGUUAGGCCGAA ACCACAUC
11048





676
AUGUGGUUC UGAGUCCG
1630
CGGACUCA CUGAUGAGGCCGUUAGGCCGAA AACCACAU
11049





682
UUCUGAGUC CGUCUCAU
1631
AUGAGACG CUGAUGAGGCCGUUAGGCCGAA ACUCAGAA
11050





686
GAGUCCGUC UCAUGGAA
1632
UUCCAUGA CUGAUGAGGCCGUUAGGCCGAA ACGGACUC
11051





688
GUCCGUCUC AUGGAAUU
1633
AAUUCCAU CUGAUGAGGCCGUUAGGCCGAA AGACGGAC
11052





696
CAUGGAAUU GAACUAUC
1634
GAUAGUUC CUGAUGAGGCCGUUAGGCCGAA AUUCCAUG
11053





702
AUUGAACUA UCUGUUGG
1635
CCAACAGA CUGAUGAGGCCGUUAGGCCGAA AGUUCAAU
11054





704
UGAACUAUC UGUUGGAG
1636
CUCCAACA CUGAUGAGGCCGUUAGGCCGAA AUAGUUCA
11055





708
CUAUCUGUU GGAGAAAA
1637
UUUUCUCC CUGAUGAGGCCGUUAGGCCGAA ACAGAUAG
11056





720
GAAAAGCUU GUCUUAAA
1638
UUUAAGAC CUGAUGAGGCCGUUAGGCCGAA AGCUUUUC
11057





723
AAGCUUGUC UUAAAUUG
1639
CAAUUUAA CUGAUGAGGCCGUUAGGCCGAA ACAAGCUU
11058





725
GCUUGUCUU AAAUUGUA
1640
UACAAUUU CUGAUGAGGCCGUUAGGCCGAA AGACAAGC
11059





726
CUUGUCUUA AAUUGUAC
1641
GUACAAUU CUGAUGAGGCCGUUAGGCCGAA AAGACAAG
11060





730
UCUUAAAUU GUACAGCA
1642
UGCUGUAC CUGAUGAGGCCGUUAGGCCGAA AUUUAAGA
11061





733
UAAAUUGUA CAGCAAGA
1643
UCUUGCUG CUGAUGAGGCCGUUAGGCCGAA ACAAUUUA
11062





750
ACUGAACUA AAUGUGGG
1644
CCCACAUU CUGAUGAGGCCGUUAGGCCGAA AGUUCAGU
11063





762
GUGGGGAUU GACUUCAA
1645
UUGAAGUC CUGAUGAGGCCGUUAGGCCGAA AUCCCCAC
11064





767
GAUUGACUU CAACUGGG
1646
CCCAGUUG CUGAUGAGGCCGUUAGGCCGAA AGUCAAUC
11065





768
AUUGACUUC AACUGGGA
1647
UCCCAGUU CUGAUGAGGCCGUUAGGCCGAA AAGUCAAU
11066





779
CUGGGAAUA CCCUUCUU
1648
AAGAAGGG CUGAUGAGGCCGUUAGGCCGAA AUUCCCAG
11067





784
AAUACCCUU CUUCGAAG
1649
CUUCGAAG CUGAUGAGGCCGUUAGGCCGAA AGGGUAUU
11068





785
AUACCCUUC UUCGAAGC
1650
GCUUCGAA CUGAUGAGGCCGUUAGGCCGAA AAGGGUAU
11069





787
ACCCUUCUU CGAAGCAU
1651
AUGCUUCG CUGAUGAGGCCGUUAGGCCGAA AGAAGGGU
11070





788
CCCUUCUUC GAAGCAUC
1652
GAUGCUUC CUGAUGAGGCCGUUAGGCCGAA AAGAAGGG
11071





796
CGAAGCAUC AGCAUAAG
1653
CUUAUGCU CUGAUGAGGCCGUUAGGCCGAA AUGCUUCG
11072





802
AUCAGCAUA AGAAACUU
1654
AAGUUUCU CUGAUGAGGCCGUUAGGCCGAA AUGCUGAU
11073





810
AAGAAACUU GUAAACCG
1655
CGGUUUAC CUGAUGAGGCCGUUAGGCCGAA AGUUUCUU
11074





813
AAACUUGUA AACCGAGA
1656
UCUCGGUU CUGAUGAGGCCGUUAGGCCGAA ACAAGUUU
11075





825
CGAGACCUA AAAACCCA
1657
UGGGUUUU CUGAUGAGGCCGUUAGGCCGAA AGGUCUCG
11076





836
AACCCAGUC UGGGAGUG
1658
CACUOCCA CUGAUGAGGCCGUUAGGCCGAA ACUGGGUU
11077





857
GAAGAAAUU UUUGAGCA
1659
UGCUCAAA CUGAUGAGGCCGUUAGGCCGAA AUUUCUUC
11078





858
AAGAAAUUU UUGAGCAC
1660
GUGCUCAA CUGAUGAGGCCGUUAGGCCGAA AAUUUCUU
11079





859
AGAAAUUUU UGAGCACC
1661
GGUGCUCA CUGAUGAGGCCGUUAGGCCGAA AAAUUUCU
11080





860
GAAAUUUUU GAGCACCU
1662
AGGUGCUC CUGAUGAGGCCGUUAGGCCGAA AAAAUUUC
11081





869
GAGCACCUU AACUAUAG
1663
CUAUAGUU CUGAUGAGGCCGUUAGGCCGAA AGGUGCUC
11082





870
AGCACCUUA ACUAUAGA
1664
UCUAUAGU CUGAUGAGGCCGUUAGGCCGAA AAGGUGCU
11083





874
CCUUAACUA UAGAUGGU
1665
ACCAUCUA CUGAUGAGGCCGUUAGGCCGAA AGUUAAGG
11084





876
UUAACUAUA GAUGGUGU
1666
ACACCAUC CUGAUGAGGCCGUUAGGCCGAA AUAGUUAA
11085





885
GAUGGUGUA ACCOGGAG
1667
CUCCGGGU CUGAUGAGGCCGUUAGGCCGAA ACACCAUC
11086





905
CCAAGGAUU GUACACCU
1668
AGGUGUAC CUGAUGAGGCCGUUAGGCCGAA AUCCUUGG
11087





908
AGGAUUGUA CACCUGUG
1669
CACAGGUG CUGAUGAGGCCGUUAGGCCGAA ACAAUCCU
11088





923
UGCAGCAUC CAGUGGGC
1670
GCCCACUG CUGAUGAGGCCGUUAGGCCGAA AUGCUGCA
11089





956
CAGCACAUU UGUCAGGG
1671
CCCUGACA CUGAUGAGGCCGUUAGGCCGAA AUGUGCUG
11090





957
AGCACAUUU GUCAGGGU
1672
ACCCUGAC CUGAUGAGGCCGUUAGGCCGAA AAUGUGCU
11091





960
ACAUUUGUC AGGGUCCA
1673
UGGACCCU CUGAUGAGGCCGUUAGGCCGAA ACAAAUGU
11092





966
GUCAGGGUC CAUGAAAA
1674
UUUUCAUG CUGAUGAGGCCGUUAGGCCGAA ACCCUGAC
11093





979
AAAAACCUU UUGUUGCU
1675
AGCAACAA CUGAUGAGGCCGUUAGGCCGAA AGGUUUUU
11094





980
AAAACCUUU UGUUGCUU
1676
AAGCAACA CUGAUGAGGCCGUUAGGCCGAA AAGGUUUU
11095





981
AAACCUUUU GUUGCUUU
1677
AAAGCAAC CUGAUGAGGCCGUUAGGCCGAA AAAGGUUU
11096





984
CCUUUUGUU GCUUUUGG
1678
CCAAAAGC CUGAUGAGGCCGUUAGGCCGAA ACAAAAGG
11097





988
UUGUUGCUU UUGGAAGU
1679
ACUUCCAA CUGAUGAGGCCGUUAGGCCGAA AGCAACAA
11098





989
UGUUGCUUU UGGAAGUG
1680
CACUUCCA CUGAUGAGGCCGUUAGGCCGAA AAGCAACA
11099





990
GUUGCUUUU GGAAGUGG
1681
CCACUUCC CUGAUGAGGCCGUUAGGCCGAA AAAGCAAC
11100





1007
CAUGGAAUC UCUGGUGG
1682
CCACCAGA CUGAUGAGGCCGUUAGGCCGAA AUUCCAUG
11101





1009
UGGAAUCUC UGGUGGAA
1683
UUCCACCA CUGAUGAGGCCGUUAGGCCGAA AGAUUCCA
11102





1038
GAGCGUGUC AGAAUCCC
1684
GGGAUUCU CUGAUGAGGCCGUUAGGCCGAA ACACGCUC
11103





1044
GUCAGAAUC CCUGCGAA
1685
UUCGCAGG CUGAUGAGGCCGUUAGGCCGAA AUUCUGAC
11104





1055
UGCGAAGUA CCUUGGUU
1686
AACCAAGG CUGAUGAGGCCGUUAGGCCGAA ACUUCGCA
11105





1059
AAGUACCUU GGUUACCC
1687
GGGUAACC CUGAUGAGGCCGUUAGGCCGAA AGGUACUU
11106





1063
ACCUUGGUU ACCCACCC
1688
GGGUGGGU CUGAUGAGGCCGUUAGGCCGAA ACCAAGGU
11107





1064
CCUUGGUUA CCCACCCC
1689
GGGGUGGG CUGAUGAGGCCGUUAGGCCGAA AACCAAGG
11108





1080
CCAGAAAUA AAAUGGUA
1690
UACCAUUU CUGAUGAGGCCGUUAGGCCGAA AUUUCUGG
11109





1088
AAAAUGGUA UAAAAAUG
1691
CAUUUUUA CUGAUGAGGCCGUUAGGCCGAA ACCAUUUU
11110





1090
AAUGGUAUA AAAAUGGA
1692
UCCAUUUU CUGAUGAGGCCGUUAGGCCGAA AUACCAUU
11111





1101
AAUGGAAUA CCCCUUGA
1693
UCAAGGGG CUGAUGAGGCCGUUAGGCCGAA AUUCCAUU
11112





1107
AUACCCCUU GAGUCCAA
1694
UUGGACUC CUGAUGAGGCCGUUAGGCCGAA AGGGGUAU
11113





1112
CCUUGAGUC CAAUCACA
1695
UGUGAUUG CUGAUGAGGCCGUUAGGCCGAA ACUCAAGG
11114





1117
AGUCCAAUC ACACAAUU
1696
AAUUGUGU CUGAUGAGGCCGUUAGGCCGAA AUUGGACU
11115





1125
CACACAAUU AAAGCGGG
1697
CCCGCUUU CUGAUGAGGCCGUUAGGCCGAA AUUGUGUG
11116





1126
ACACAAUUA AAGCGGGG
1698
CCCCGCUU CUGAUGAGGCCGUUAGGCCGAA AAUUGUGU
11117





1140
GGGCAUGUA CUGACGAU
1699
AUCGUCAG CUGAUGAGGCCGUUAGGCCGAA ACAUGCCC
11118





1149
CUGACGAUU AUGGAAGU
1700
ACUUCCAU CUGAUGAGGCCGUUAGGCCGAA AUCGUCAG
11119





1150
UGACGAUUA UGGAAGUG
1701
CACUUCCA CUGAUGAGGCCGUUAGGCCGAA AAUCGUCA
11120





1180
CAGGAAAUU ACACUGUC
1702
GACAGUGU CUGAUGAGGCCGUUAGGCCGAA AUUUCCUG
11121





1181
AGGAAAUUA CACUGUCA
1703
UGACAGUG CUGAUGAGGCCGUUAGGCCGAA AAUUUCCU
11122





1188
UACACUGUC AUCCUUAC
1704
GUAAGGAU CUGAUGAGGCCGUUAGGCCGAA ACAGUGUA
11123





1191
ACUGUCAUC CUUACCAA
1705
UUGGUAAG CUGAUGAGGCCGUUAGGCCGAA AUGACAGU
11124





1194
GUCAUCCUU ACCAAUCC
1706
GGAUUGGU CUGAUGAGGCCGUUAGGCCGAA AGGAUGAC
11125





1195
UCAUCCUUA CCAAUCCC
1707
GGGAUUGG CUGAUGAGGCCGUUAGGCCGAA AAGGAUGA
11126





1201
UUACCAAUC CCAUUUCA
1708
UGAAAUGG CUGAUGAGGCCGUUAGGCCGAA AUUGGUAA
11127





1206
AAUCCCAUU UCAAAGGA
1709
UCCUUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGGAUU
11128





1207
AUCCCAUUU CAAAGGAG
1710
CUCCUUUG CUGAUGAGGCCGUUAGGCCGAA AAUGGGAU
11129





1208
UCCCAUUUC AAAGGAGA
1711
UCUCCUUU CUGAUGAGGCCGUUAGGCCGAA AAAUGGGA
11130





1233
CAUGUGGUC UCUCUGGU
1712
ACCAGAGA CUGAUGAGGCCGUUAGGCCGAA ACCACAUG
11131





1235
UGUGGUCUC UCUGGUUG
1713
CAACCAGA CUGAUGAGGCCGUUAGGCCGAA AGACCACA
11132





1237
UGGUCUCUC UGGUUGUG
1714
CACAACCA CUGAUGAGGCCGUUAGGCCGAA AGAGACCA
11133





1242
UCUCUGGUU GUGUAUGU
1715
ACAUACAC CUGAUGAGGCCGUUAGGCCGAA ACCAGAGA
11134





1247
GGUUGUGUA UGUCCCAC
1716
GUGGGACA CUGAUGAGGCCGUUAGGCCGAA ACACAACC
11135





1251
GUGUAUGUC CCACCCCA
1717
UGGGGUGG CUGAUGAGGCCGUUAGGCCGAA ACAUACAC
11136





1263
CCCCAGAUU GGUGAGAA
1718
UUCUCACC CUGAUGAGGCCGUUAGGCCGAA AUCUGGGG
11137





1274
UGAGAAAUC UCUAAUCU
1719
AGAUUAGA CUGAUGAGGCCGUUAGGCCGAA AUUUCUCA
11138





1276
AGAAAUCUC UAAUCUCU
1720
AGAGAUUA CUGAUGAGGCCGUUAGGCCGAA AGAUUUCU
11139





1278
AAAUCUCUA AUCUCUCC
1721
GGAGAGAU CUGAUGAGGCCGUUAGGCCGAA AGAGAUUU
11140





1281
UCUCUAAUC UCUCCUGU
1722
ACAGGAGA CUGAUGAGGCCGUUAGGCCGAA AUUAGAGA
11141





1283
UCUAAUCUC UCCUGUGG
1723
CCACAGGA CUGAUGAGGCCGUUAGGCCGAA AGAUUAGA
11142





1285
UAAUCUCUC CUGUGGAU
1724
AUCCACAG CUGAUGAGGCCGUUAGGCCGAA AGAGAUUA
11143





1294
CUGUGGAUU CCUACCAG
1725
CUGGUAGG CUGAUGAGGCCGUUAGGCCGAA AUCCACAG
11144





1295
UGUGGAUUC CUACCAGU
1726
ACUGGUAG CUGAUGAGGCCGUUAGGCCGAA AAUCCACA
11145





1298
GGAUUCCUA CCAGUACG
1727
CGUACUGG CUGAUGAGGCCGUUAGGCCGAA AGGAAUCC
11146





1304
CUACCAGUA CGGCACCA
1728
UGGUGCCG CUGAUGAGGCCGUUAGGCCGAA ACUGGUAG
11147





1315
GCACCACUC AAACGCUG
1729
CAGCGUUU CUGAUGAGGCCGUUAGGCCGAA AGUGGUGC
11148





1330
UGACAUGUA CGGUCUAU
1730
AUAGACCG CUGAUGAGGCCGUUAGGCCGAA ACAUGUCA
11149





1335
UGUACGGUC UAUGCCAU
1731
AUGGCAUA CUGAUGAGGCCGUUAGGCCGAA ACCGUACA
11150





1337
UACGGUCUA UGCCAUUC
1732
GAAUGGCA CUGAUGAGGCCGUUAGGCCGAA AGACCGUA
11151





1344
UAUGCCAUU CCUCCCCC
1733
GGGGGAGG CUGAUGAGGCCGUUAGGCCGAA AUGGCAUA
11152





1345
AUGCCAUUC CUCCCCCG
1734
CGGGGGAG CUGAUGAGGCCGUUAGGCCGAA AAUGGCAU
11153





1348
CCAUUCCUC CCCCGCAU
1735
AUGCGGGG CUGAUGAGGCCGUUAGGCCGAA AGGAAUGG
11154





1357
CCCCGCAUC ACAUCCAC
1736
GUGGAUGU CUGAUGAGGCCGUUAGGCCGAA AUGCGGGG
11155





1362
CAUCACAUC CACUGGUA
1737
UACCAGUG CUGAUGAGGCCGUUAGGCCGAA AUGUGAUG
11156





1370
CCACUGGUA UUGGCAGU
1738
ACUGCCAA CUGAUGAGGCCGUUAGGCCGAA ACCAGUGG
11157





1372
ACUGGUAUU GGCAGUUG
1739
CAACUGCC CUGAUGAGGCCGUUAGGCCGAA AUACCAGU
11158





1379
UUGGCAGUU GGAGGAAG
1740
CUUCCUCC CUGAUGAGGCCGUUAGGCCGAA ACUGCCAA
11159





1416
CAAGCUGUC UCAGUGAC
1741
GUCACUGA CUGAUGAGGCCGUUAGGCCGAA ACAGCUUG
11160





1418
AGCUGUCUC AGUGACAA
1742
UUGUCACU CUGAUGAGGCCGUUAGGCCGAA AGACAGCU
11161





1433
AAACCCAUA CCCUUGUG
1743
CACAAGGG CUGAUGAGGCCGUUAGGCCGAA AUGGGUUU
11162





1438
CAUACCCUU GUGAAGAA
1744
UUCUUCAC CUGAUGAGGCCGUUAGGCCGAA AGGGUAUG
11163





1466
GGAGGACUU CCAGGGAG
1745
CUCCCUGG CUGAUGAGGCCGUUAGGCCGAA AGUCCUCC
11164





1467
GAGGACUUC CAGGGAGG
1746
CCUCCCUG CUGAUGAGGCCGUUAGGCCGAA AAGUCCUC
11165





1480
GAGGAAAUA AAAUUGAA
1747
UUCAAUUU CUGAUGAGGCCGUUAGGCCGAA AUUUCCUC
11166





1485
AAUAAAAUU GAAGUUAA
1748
UUAACUUC CUGAUGAGGCCGUUAGGCCGAA AUUUUAUU
11167





1491
AUUGAAGUU AAUAAAAA
1749
UUUUUAUU CUGAUGAGGCCGUUAGGCCGAA ACUUCAAU
11168





1492
UUGAAGUUA AUAAAAAU
1750
AUUUUUAU CUGAUGAGGCCGUUAGGCCGAA AACUUCAA
11169





1495
AAGUUAAUA AAAAUCAA
1751
UUGAUUUU CUGAUGAGGCCGUUAGGCCGAA AUUAACUU
11170





1501
AUAAAAAUC AAUUUGCU
1752
AGCAAAUU CUGAUGAGGCCGUUAGGCCGAA AUUUUUAU
11171





1505
AAAUCAAUU UGCUCUAA
1753
UUAGAGCA CUGAUGAGGCCGUUAGGCCGAA AUUGAUUU
11172





1506
AAUCAAUUU GCUCUAAU
1754
AUUAGAGC CUGAUGAGGCCGUUAGGCCGAA AAUUGAUU
11173





1510
AAUUUGCUC UAAUUGAA
1755
UUCAAUUA CUGAUGAGGCCGUUAGGCCGAA AGCAAAUU
11174





1512
UUUGCUCUA AUUGAAGG
1756
CCUUCAAU CUGAUGAGGCCGUUAGGCCGAA AGAGCAAA
11175





1515
GCUCUAAUU GAAGGAAA
1757
UUUCCUUC CUGAUGAGGCCGUUAGGCCGAA AUUAGAGC
11176





1536
AAAACUGUA AGUACCCU
1758
AGGGUACU CUGAUGAGGCCGUUAGGCCGAA ACAGUUUU
11177





1540
CUGUAAGUA CCCUUGUU
1759
AACAAGGG CUGAUGAGGCCGUUAGGCCGAA ACUUACAG
11178





1545
AGUACCCUU GUUAUCCA
1760
UGGAUAAC CUGAUGAGGCCGUUAGGCCGAA AGGGUACU
11179





1548
ACCCUUGUU AUCCAAGC
1761
GCUUGGAU CUGAUGAGGCCGUUAGGCCGAA ACAAGGGU
11180





1549
CCCUUGUUA UCCAAGCG
1762
CGCUUGGA CUGAUGAGGCCGUUAGGCCGAA AACAAGGG
11181





1551
CUUGUUAUC CAAGCGGC
1763
GCCGCUUG CUGAUGAGGCCGUUAGGCCGAA AUAACAAG
11182





1568
AAAUGUGUC AGCUUUGU
1764
ACAAAGCU CUGAUGAGGCCGUUAGGCCGAA ACACAUUU
11183





1573
UGUCAGCUU UGUACAAA
1765
UUUGUACA CUGAUGAGGCCGUUAGGCCGAA AGCUGACA
11184





1574
GUCAGCUUU GUACAAAU
1766
AUUUGUAC CUGAUGAGGCCGUUAGGCCGAA AAGCUGAC
11185





1577
AGCUUUGUA CAAAUGUG
1767
CACAUUUG CUGAUGAGGCCGUUAGGCCGAA ACAAAGCU
11186





1593
GAAGCGGUC AACAAAGU
1768
ACUUUGUU CUGAUGAGGCCGUUAGGCCGAA ACCGCUUC
11187





1602
AACAAAGUC GGGAGAGG
1769
CCUCUCCC CUGAUGAGGCCGUUAGGCCGAA ACUUUGUU
11188





1623
AGGGUGAUC UCCUUCCA
1770
UGGAAGGA CUGAUGAGGCCGUUAGGCCGAA AUCACCCU
11189





1625
GGUGAUCUC CUUCCACG
1771
CGUGGAAG CUGAUGAGGCCGUUAGGCCGAA AGAUCACC
11190





1628
GAUCUCCUU CCACGUGA
1772
UCACGUGG CUGAUGAGGCCGUUAGGCCGAA AGGAGAUC
11191





1629
AUCUCCUUC CACGUGAC
1773
GUCACGUG CUGAUGAGGCCGUUAGGCCGAA AAGGAGAU
11192





1645
CCAGGGGUC CUGAAAUU
1774
AAUUUCAG CUGAUGAGGCCGUUAGGCCGAA ACCCCUGG
11193





1653
CCUGAAAUU ACUUUGCA
1775
UGCAAAGU CUGAUGAGGCCGUUAGGCCGAA AUUUCAGG
11194





1654
CUGAAAUUA CUUUGCAA
1776
UUGCAAAG CUGAUGAGGCCGUUAGGCCGAA AAUUUCAG
11195





1657
AAAUUACUU UGCAACCU
1777
AGGUUGCA CUGAUGAGGCCGUUAGGCCGAA AGUAAUUU
11196





1658
AAUUACUUU GCAACCUG
1778
CAGGUUGC CUGAUGAGGCCGUUAGGCCGAA AAGUAAUU
11197





1697
GAGCGUGUC UUUGUGGU
1779
ACCACAAA CUGAUGAGGCCGUUAGGCCGAA ACACGCUC
11198





1699
GCGUGUCUU UGUGGUGC
1780
GCACCACA CUGAUGAGGCCGUUAGGCCGAA AGACACGC
11199





1700
CGUGUCUUU GUGGUGCA
1781
UGCACCAC CUGAUGAGGCCGUUAGGCCGAA AAGACACG
11200





1721
AGACAGAUC UACGUUUG
1782
CAAACGUA CUGAUGAGGCCGUUAGGCCGAA AUCUGUCU
11201





1723
ACAGAUCUA CGUUUGAG
1783
CUCAAACG CUGAUGAGGCCGUUAGGCCGAA AGAUCUGU
11202





1727
AUCUACGUU UGAGAACC
1784
GGUUCUCA CUGAUGAGGCCGUUAGGCCGAA ACGUAGAU
11203





1728
UCUACGUUU GAGAACCU
1785
AGGUUCUC CUGAUGAGGCCGUUAGGCCGAA AACGUAGA
11204





1737
GAGAACCUC ACAUGGUA
1786
UACCAUGU CUGAUGAGGCCGUUAGGCCGAA AGGUUCUC
11205





1745
CACAUGGUA CAAGCUUG
1787
CAAGCUUG CUGAUGAGGCCGUUAGGCCGAA ACCAUGUG
11206





1752
UACAAGCUU GGCCCACA
1788
UGUGGGCC CUGAUGAGGCCGUUAGGCCGAA AGCUUGUA
11207





1765
CACAGCCUC UGCCAAUC
1789
GAUUGGCA CUGAUGAGGCCGUUAGGCCGAA AGGCUGUG
11208





1773
CUGCCAAUC CAUGUGGG
1790
CCCACAUG CUGAUGAGGCCGUUAGGCCGAA AUUGGCAG
11209





1787
GGGAGAGUU GCCCACAC
1791
GUGUGGGC CUGAUGAGGCCGUUAGGCCGAA ACUCUCCC
11210





1800
ACACCUGUG UGCAAGAA
1792
UUCUUGCA CUGAUGAGGCCGUUAGGCCGAA ACAGGUGU
11211





1801
CACCUGGUG GCAAGAAC
1793
GUUCUUGC CUGAUGAGGCCGUUAGGCCGAA AACAGGUG
11212





1811
CAAGAACUU GGAUACUC
1794
GAGUAUCC CUGAUGAGGCCGUUAGGCCGAA AGUUCUUG
11213





1816
ACUUGGAUA CUCUUUGG
1795
CCAAAGAG CUGAUGAGGCCGUUAGGCCGAA AUCCAAGU
11214





1819
UGGAUACUC UUUGGAAA
1796
UUUCCAAA CUGAUGAGGCCGUUAGGCCGAA AGUAUCCA
11215





1821
GAUACUCUU UGGAAAUU
1797
AAUUUCCA CUGAUGAGGCCGUUAGGCCGAA AGAGUAUC
11216





1822
AUACUCUUU GGAAAUUG
1798
CAAUUUCC CUGAUGAGGCCGUUAGGCCGAA AAGAGUAU
11217





1829
UUGGAAAUU GAAUGCCA
1799
UGGCAUUC CUGAUGAGGCCGUUAGGCCGAA AUUUCCAA
11218





1844
CACCAUGUU CUCUAAUA
1800
UAUUAGAG CUGAUGAGGCCGUUAGGCCGAA ACAUGGUG
11219





1845
ACCAUGUUC UCUAAUAG
1801
CUAUUAGA CUGAUGAGGCCGUUAGGCCGAA AACAUGGU
11220





1847
CAUGUUCUC UAAUAGCA
1802
UGCUAUUA CUGAUGAGGCCGUUAGGCCGAA AGAACAUG
11221





1849
UGUUCUCUA AUAGCACA
1803
UGUGCUAU CUGAUGAGGCCGUUAGGCCGAA AGAGAACA
11222





1852
UCUCUAAUA GCACAAAU
1804
AUUUGUGC CUGAUGAGGCCGUUAGGCCGAA AUUAGAGA
11223





1866
AAUGACAUU UUGAUCAU
1805
AUGAUCAA CUGAUGAGGCCGUUAGGCCGAA AUGUCAUU
11224





1867
AUGACAUUU UGAUCAUG
1806
CAUGAUCA CUGAUGAGGCCGUUAGGCCGAA AAUGUCAU
11225





1868
UGACAUUUC GAUCAUGG
1807
CCAUGAUC CUGAUGAGGCCGUUAGGCCGAA AAAUGUCA
11226





1872
AUUUUGAUC AUGGAGCU
1808
AGCUCCAU CUGAUGAGGCCGUUAGGCCGAA AUCAAAAU
11227





1881
AUGGAGCUU AAGAAUGC
1809
GCAUUCUU CUGAUGAGGCCGUUAGGCCGAA AGCUCCAU
11228





1882
UGGACCUUA AGAAUGCA
1810
UGCAUUCU CUGAUGAGGCCGUUAGGCCGAA AAGCUCCA
11229





1892
GAAUGCAUC CUUGCAGG
1811
CCUGCAAG CUGAUGAGGCCGUUAGGCCGAA AUGCAUUC
11230





1895
UGCAUCCUU GCAGGACC
1812
GGUCCUGC CUGAUGAGGCCGUUAGGCCGAA AGGAUCCA
11231





1913
AGGAGACUA UGUCUGCC
1813
GGCAGACA CUGAUGAGGCCGUUAGGCCGAA AGUCUCCU
11232





1917
GACUAUGUC UGCCUUGC
1814
GCAAGGCA CUGAUGAGGCCGUUAGGCCGAA ACAUAGUC
11233





1923
GUCUGCCUU GCUCAAGA
1815
UCUUGAGC CUGAUGAGGCCGUUAGGCCGAA AGGCAGAC
11234





1927
GCCUUGCUC AAGACAGG
1816
CCUGUCUU CUGAUGAGGCCGUUAGGCCGAA AGCAAGGC
11235





1954
AAAGACAUU GCGUGGUC
1817
GACCACGC CUGAUGAGGCCGUUAGGCCGAA AUGUCUUU
11236





1962
UGCGUGGUC AGGCAGCU
1818
AGCUGCCU CUGAUGAGGCCGUUAGGCCGAA ACCACGCA
11237





1971
AGGCAGCUC ACAGUCCU
1819
AGGACUGU CUGAUGAGGCCGUUAGGCCGAA AGCUGCCU
11238





1977
CUCACAGUC CUAGAGCG
1820
CGCUCUAG CUGAUGAGGCCGUUAGGCCGAA ACUGUGAG
11239





1980
ACAGUCCUA GAGCGUGU
1821
ACACGCUC CUGAUGAGGCCGUUAGGCCGAA AGGACUGU
11240





2001
CCCACGAUC ACAGGAAA
1822
UUUCCUGU CUGAUGAGGCCGUUAGGCCGAA AUCGUGGG
11241





2020
UGGAGAAUC AGACGACA
1823
UGUCGUCU CUGAUGAGGCCGUUAGGCCGAA AUUCUCCA
11242





2032
CGACAAGUA UUGGGGAA
1824
UUCCCCAA CUGAUGAGGCCGUUAGGCCGAA ACUUGUCG
11243





2034
ACAAGUAUU GGGGAAAG
1825
CUUUCCCC CUGAUGAGGCCGUUAGGCCGAA AUACUUGU
11244





2046
GAAAGCAUC GAAGUCUC
1826
GAGACUUC CUGAUGAGGCCGUUAGGCCGAA AUGCUUUC
11245





2052
AUCGAAGUC UCAUGCAC
1827
GUCCAUGA CUGAUGAGGCCGUUAGGCCGAA ACUUCGAU
11246





2054
CGAAGUCUC AUGCACGG
1828
CCGUGCAU CUGAUGAGGCCGUUAGGCCGAA AGACUUCG
11247





2066
CACGGCAUC UGGGAAUC
1829
GAUUCCCA CUGAUGAGGCCGUUAGGCCGAA AUGCCGUG
11248





2074
CUGGGAAUC CCCCUCCA
1830
UGGAGGGG CUGAUGAGGCCGUUAGGCCGAA AUUCCCAG
11249





2080
AUCCCCCUC CACAGAUC
1831
GAUCUGUG CUGAUGAGGCCGUUAGGCCGAA AGGGGGAU
11250





2088
CCACAGAUC AUGUGGUU
1832
AACCACAU CUGAUGAGGCCGUUAGGCCGAA AUCUGUGG
11251





2096
CAUGUGGUU UAAAGAUA
1833
UAUCUUUA CUGAUGAGGCCGUUAGGCCGAA ACCACAUG
11252





2097
AUGUGGUUU AAAGAUAA
1834
UUAUCUUU CUGAUGAGGCCGUUAGGCCGAA AACCACAU
11253





2098
UGUGGUUUA AAGAUAAU
1835
AUUAUCUU CUGAUGAGGCCGUUAGGCCGAA AAACCACA
11254





2104
UUAAAGAUA AUGAGACC
1836
GGUCUCAU CUGAUGAGGCCGUUAGGCCGAA AUCUUUAA
11255





2115
GAGACCCUU GUAGAAGA
1837
UCUUCUAC CUGAUGAGGCCGUUAGGCCGAA AGGGUCUC
11256





2118
ACCCUUGUA GAAGACUC
1838
GAGUCCUC CUGAUGAGGCCGUUAGGCCGAA ACAAGGGU
11257





2126
AGAAGACUC AGGCAUUG
1839
CAAUGCCU CUGAUGAGGCCGUUAGGCCGAA AGUCUUCU
11258





2133
UCAGGCAUU GUAUUGAA
1840
UUCAAUAC CUGAUGAGGCCGUUAGGCCGAA AUGCCUGA
11259





2136
GGCAUUGUA UUGAAGGA
1841
UCCUUCAA CUGAUGAGGCCGUUAGGCCGAA ACAAUGCC
11260





2138
CAUUGUAUU GAAGGAUG
1842
CAUCCUUC CUGAUGAGGCCGUUAGGCCGAA AUACAAUG
11261





2160
CGGAACCUC ACUAUCCG
1843
CGGAUAGU CUGAUGAGGCCGUUAGGCCGAA AGGUUCCG
11262





2164
ACCUCACUA UCCGCAGA
1844
UCUGCGGA CUGAUGAGGCCGUUAGGCCGAA AGUGAGGU
11263





2166
CUCACUAUC CGCAGAGU
1845
ACUCUGCG CUGAUGAGGCCGUUAGGCCGAA AUAGUGAG
11264





2196
GAAGGCCUC UACACCUG
1846
CAGGUGUA CUGAUGAGGCCGUUAGGCCGAA AGGCCUUC
11265





2198
AGGCCUCUA CACCUGCC
1847
GGCAGGUG CUGAUGAGGCCGUUAGGCCGAA AGAGGCCU
11266





2220
UGCAGUGUU CUUGGCUG
1848
CAGCCAAG CUGAUGAGGCCGUUAGGCCGAA ACACUCCA
11267





2221
GCAGUGUUC UUGGCUGU
1849
ACAGCCAA CUGAUGAGGCCGUUAGGCCGAA AACACUGC
11268





2223
AGUGUUCUU GGCUGUGC
1850
GCACAGCC CUGAUGAGGCCGUUAGGCCGAA AGAACACU
11269





2246
GGAGGCAUU UUUCAUAA
1851
UUAUGAAA CUGAUGAGGCCGUUAGGCCGAA AUGCCUCC
11270





2247
GAGGCAUUU UUCAUAAU
1852
AUUAUGAA CUGAUGAGGCCGUUAGGCCGAA AAUGCCUC
11271





2248
AGGCAUUUU UCAUAAUA
1853
UAUUAUGA CUGAUGAGGCCGUUAGGCCGAA AAAUGCCU
11272





2249
GGCAUUUUU CAUAAUAG
1854
CUAUUAUG CUGAUGAGGCCGUUAGGCCGAA AAAAUGCC
11273





2250
GCAUUUUUC AUAAUAGA
1855
UCUAUUAU CUGAUGAGGCCGUUAGGCCGAA AAAAAUGC
11274





2253
UUUUUCAUA AUAGAAGG
1856
CCUUCUAU CUGAUGAGGCCGUUAGGCCGAA AUGAAAAA
11275





2256
UUCAUAAUA GAAGGUGC
1857
GCACCUUC CUGAUGAGGCCGUUAGGCCGAA AUUAUGAA
11276





2282
GACGAACUU GGAAAUCA
1858
UGAUUUCC CUGAUGAGGCCGUUAGGCCGAA AGUUCGUC
11277





2289
UUGGAAAUC AUUAUUCU
1859
AGAAUAAU CUGAUGAGGCCGUUAGGCCGAA AUUUCCAA
11278





2292
GAAAUCAUU AUUCUAGU
1860
ACUAGAAU CUGAUGAGGCCGUUAGGCCGAA AUGAUUUC
11279





2293
AAAUCAUUA UUCUAGUA
1861
UACUAGAA CUGAUGAGGCCGUUAGGCCGAA AAUGAUUU
11280





2295
AUCAUUAUU CUAGUAGG
1862
CCUACUAG CUGAUGAGGCCGUUAGGCCGAA AUAAUGAU
11281





2296
UCAUUAUUC UAGUAGGC
1863
GCCUACUA CUGAUGAGGCCGUUAGGCCGAA AAUAAUGA
11282





2298
AUUAUUCUA GUAGGCAC
1864
GUGCCUAC CUGAUGAGGCCGUUAGGCCGAA AGAAUAAU
11283





2301
AUUCUAGUA GGCACGAC
1865
GUCGUGCC CUGAUGAGGCCGUUAGGCCGAA ACUAGAAU
11284





2316
ACGGUGAUU GCCAUGUU
1866
AACAUGGC CUGAUGAGGCCGUUAGGCCGAA AUCACCGU
11285





2324
UGCCAUGUU CUUCUGGC
1867
GCCAGAAG CUGAUGAGGCCGUUAGGCCGAA ACAUGGCA
11286





2325
GCCAUGUUC UUCUGGCU
1868
AGCCAGAA CUGAUGAGGCCGUUAGGCCGAA AACAUGGC
11287





2327
CAUGUUCUU CUGGCUAC
1869
GUAGCCAG CUGAUGAGGCCGUUAGGCCGAA AGAACAUG
11288





2328
AUGUUCUUC UGGCUACU
1870
AGUAGCCA CUGAUGAGGCCGUUAGGCCGAA AAGAACAU
11289





2334
UUCUGGCUA CUUCUUGU
1871
ACAAGAAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGAA
11290





2337
UGGCUACUU CUUGUCAU
1872
AUGACAAG CUGAUGAGGCCGUUAGGCCGAA AGUAGCCA
11291





2338
GGCUACUUC UUGUCAUC
1873
GAUGACAA CUGAUGAGGCCGUUAGGCCGAA AAGUAGCC
11292





2340
CUACUUCUU GUCAUCAU
1874
AUGAUGAC CUGAUGAGGCCGUUAGGCCGAA AGAAGUAG
11293





2343
CUUCUUGUC AUCAUCCU
1875
AGGAUGAU CUGAUGAGGCCGUUAGGCCGAA ACAAGAAG
11294





2346
CUUGUCAUC AUCCUAGG
1876
CCUAGGAU CUGAUGAGGCCGUUAGGCCGAA AUGACAAG
11295





2349
GUCAUCAUC CUAGGGAC
1877
GUCCCUAG CUGAUGAGGCCGUUAGGCCGAA AUGAUGAC
11296





2352
AUCAUCCUA GGGACCGU
1878
ACGGUCCC CUGAUGAGGCCGUUAGGCCGAA AGGAUGAU
11297





2361
GGGACCGUU AAGCGGGC
1879
GCCCGCUU CUGAUGAGGCCGUUAGGCCGAA ACGGUCCC
11298





2362
GGACCGUUA AGCGGGCC
1880
GGCCCGCU CUGAUGAGGCCGUUAGGCCGAA AACGGUCC
11299





2396
GACAGGCUA CUUGUCCA
1881
UGGACAAG CUGAUGAGGCCGUUAGGCCGAA AGCCUGUC
11300





2399
AGGCUACUU GUCCAUCG
1882
CGAUGGAC CUGAUGAGGCCGUUAGGCCGAA AGUAGCCU
11301





2402
CUACUUGUC CAUCGUCA
1883
UGACGAUG CUGAUGAGGCCGUUAGGCCGAA ACAAGUAG
11302





2406
UUGUCCAUC GUCAUGGA
1884
UCCAUGAC CUGAUGAGGCCGUUAGGCCGAA AUGGACAA
11303





2409
UCCAUCGUC AUGGAUCC
1885
GGAUCCAU CUGAUGAGGCCGUUAGGCCGAA ACGAUGGA
11304





2416
UCAUGGAUC CAGAUGAA
1886
UUCAUCUG CUGAUGAGGCCGUUAGGCCGAA AUCCAUGA
11305





2427
GAUGAACUC CCAUUGGA
1887
UCCAAUGG CUGAUGAGGCCGUUAGGCCGAA AGUUCAUC
11306





2432
ACUCCCAUU GGAUGAAC
1888
GUUCAUCC CUGAUGAGGCCGUUAGGCCGAA AUGGGAGU
11307





2443
AUGAACAUU GUGAACGA
1889
UCGUUCAC CUGAUGAGGCCGUUAGGCCGAA AUGUUCAU
11308





2458
GACUGCCUU AUGAUGCC
1890
GGCAUCAU CUGAUGAGGCCGUUAGGCCGAA AGGCAGUC
11309





2459
ACUGCCUUA UGAUGCCA
1891
UGGCAUCA CUGAUGAGGCCGUUAGGCCGAA AAGGCAGU
11310





2480
AUGGGAAUU CCCCAGAG
1892
CUCUGGGG CUGAUGAGGCCGUUAGGCCGAA AUUCCCAU
11311





2481
UGGGAAUUC CCCAGAGA
1893
UCUCUGGG CUGAUGAGGCCGUUAGGCCGAA AAUUCCCA
11312





2502
CUGAACCUA GGUAAGCC
1894
GGCUUACC CUGAUGAGGCCGUUAGGCCGAA AGGUUCAG
11313





2506
ACCUAGGUA AGCCUCUU
1895
AAGAGGCU CUGAUGAGGCCGUUAGGCCGAA ACCUAGGU
11314





2512
GUAAGCCUC UUGGCCGU
1896
ACGGCCAA CUGAUGAGGCCGUUAGGCCGAA AGGCUUAC
11315





2514
AAGCCUCUU GGCCGUGG
1897
CCACGGCC CUGAUGAGGCCGUUAGGCCGAA AGAGGCUU
11316





2528
UGGUGCCUU UGGCCAAG
1898
CUUGGCCA CUGAUGAGGCCGUUAGGCCGAA AGGCACCA
11317





2529
GGUGCCUUU GGCCAAGA
1899
UCUUGGCC CUGAUGAGGCCGUUAGGCCGAA AAGGCACC
11318





2541
CAAGAGAUU GAAGCAGA
1900
UCUGCUUC CUGAUGAGGCCGUUAGGCCGAA AUCUCUUG
11319





2555
AGAUGCCUU UGGAAUUG
1901
CAAUUCCA CUGAUGAGGCCGUUAGGCCGAA AGGCAUCU
11320





2556
GAUGCCUUU GGAAUUGA
1902
UCAAUUCC CUGAUGAGGCCGUUAGGCCGAA AAGGCAUC
11321





2562
UUUGGAAUU GACAAGAC
1903
GUCUUGUC CUGAUGAGGCCGUUAGGCCGAA AUUCCAAA
11322





2578
CAGCAACUU GCAGGACA
1904
UGUCCUGC CUGAUGAGGCCGUUAGGCCGAA AGUUGCUG
11323





2589
AGGACAGUA GCAGUCAA
1905
UUGACUGC CUGAUGAGGCCGUUAGGCCGAA ACUGUCCU
11324





2595
GUAGCAGUC AAAAUGUU
1906
AACAUUUU CUGAUGAGGCCGUUAGGCCGAA ACUGCUAC
11325





2603
CAAAAUGUU GAAAGAAG
1907
CUUCUUUC CUGAUGAGGCCGUUAGGCCGAA ACAUUUUG
11326





2632
GUGAGCAUC GAGCUCUC
1908
GAGAGCUC CUGAUGAGGCCGUUAGGCCGAA AUGCUCAC
11327





2638
AUCGAGCUC UCAUGUCU
1909
AGACAUGA CUGAUGAGGCCGUUAGGCCGAA AGCUCGAU
11328





2640
CGAGCUCUC AUGUCUGA
1910
UCAGACAU CUGAUGAGGCCGUUAGGCCGAA AGAGCUCG
11329





2645
UCUCAUGUC UGAACUCA
1911
UGAGUUCA CUGAUGAGGCCGUUAGGCCGAA ACAUGAGA
11330





2652
UCUGAACUC AAGAUCCU
1912
AGGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGUUCAGA
11331





2658
CUCAAGAUC CUCAUUCA
1913
UGAAUGAG CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
11332





2661
AAGAUCCUC AUUCAUAU
1914
AUAUGAAU CUGAUGAGGCCGUUAGGCCGAA AGGAUCUU
11333





2664
AUCCUCAUU CAUAUUGG
1915
CCAAUAUG CUGAUGAGGCCGUUAGGCCGAA AUGAGGAU
11334





2665
UCCUCAUUC AUAUUGGU
1916
ACCAAUAU CUGAUGAGGCCGUUAGGCCGAA AAUGAGGA
11335





2668
UCAUUCAUA UUGGUCAC
1917
GUGACCAA CUGAUGAGGCCGUUAGGCCGAA AUGAAUGA
11336





2670
AUUCAUAUU GGUCACCA
1918
UGGUGACC CUGAUGAGGCCGUUAGGCCGAA AUAUGAAU
11337





2674
AUAUUGGUC ACCAUCUC
1919
GAGAUGGU CUGAUGAGGCCGUUAGGCCGAA ACCAAUAU
11338





2680
GUCACCAUC UCAAUGUG
1920
CACAUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGUGAC
11339





2682
CACCAUCUC AAUGUGGU
1921
ACCACAUU CUGAUGAGGCCGUUAGGCCGAA AGAUGGUG
11340





2691
AAUGUGGUC AACCUUCU
1922
AGAAGGUU CUGAUGAGGCCGUUAGGCCGAA ACCACAUU
11341





2697
GUCAACCUU CUAGGUGC
1923
GCACCUAG CUGAUGAGGCCGUUAGGCCGAA AGGUUUAC
11342





2698
UCAACCUUC UAGGUGCC
1924
GGCACCUA CUGAUGAGGCCGUUAGGCCGAA AAGGUUGA
11343





2700
AACCUUCUA GGUGCCUG
1925
CAGGCACC CUGAUGAGGCCGUUAGGCCGAA AGAAGGUU
11344





2710
GUGCCUGUA CCAAGCCA
1926
UGGCUUGG CUGAUGAGGCCGUUAGGCCGAA ACAGGCAC
11345





2730
GGGCCACUC AUGGUGAU
1927
AUCACCAU CUGAUGAGGCCGUUAGGCCGAA AGUGGCCC
11346





2739
AUGGUGAUU GUGGAAUU
1928
AAUUCCAC CUGAUGAGGCCGUUAGGCCGAA AUCACCAU
11347





2747
UGUGGAAUU CUGCAAAU
1929
AUUUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUCCACA
11348





2748
GUGGAAUUC UGCAAAUU
1930
AAUUUGCA CUGAUGAGGCCGUUAGGCCGAA AAUUCCAC
11349





2756
CUGCAAAUU UGGAAACC
1931
GGUUUCCA CUGAUGAGGCCGUUAGGCCGAA AUUUGCAG
11350





2757
UGCAAAUUU GGAAACCU
1932
AGGUUUCC CUGAUGAGGCCGUUAGGCCGAA AAUUUGCA
11351





2768
AAACCUGUC CACUUACC
1933
GGUAAGUG CUGAUGAGGCCGUUAGGCCGAA ACAGGUUU
11352





2773
UGUCCACUU ACCUGAGG
1934
CCUCAGGU CUGAUGAGGCCGUUAGGCCGAA AGUGGACA
11353





2774
GUCCACUUA CCUGAGGA
1935
UCCUCAGG CUGAUGAGGCCGUUAGGCCGAA AAGUGGAC
11354





2798
AAAUGAAUU UGUCCCCU
1936
AGGGGACA CUGAUGAGGCCGUUAGGCCGAA AUUCAUUU
11355





2799
AAUGAAUUU GUCCCCUA
1937
UAGGGGAC CUGAUGAGGCCGUUAGGCCGAA AAUUCAUU
11356





2802
GAAUUUGUC CCCUACAA
1938
UUGUAGGG CUGAUGAGGCCGUUAGGCCGAA ACAAAUUC
11357





2807
UGUCCCCUA CAAGACCA
1939
UGGUCUUG CUGAUGAGGCCGUUAGGCCGAA AGGGGACA
11358





2828
GGCACGAUU CCGUCAAG
1940
CUUGACGG CUGAUGAGGCCGUUAGGCCGAA AUCGUGCC
11359





2829
GCACGAUUC CGUCAAGG
1941
CCUUGACG CUGAUGAGGCCGUUAGGCCGAA AAUCGUGC
11360





2833
GAUUCCGUC AAGGGAAA
1942
UUUCCCUU CUGAUGAGGCCGUUAGGCCGAA ACGGAAUC
11361





2846
GAAAGACUA CGUUGGAG
1943
CUCCAACG CUGAUGAGGCCGUUAGGCCGAA AGUCUUUC
11362





2850
GACUACGUU GGAGCAAU
1944
AUUGCUCC CUGAUGAGGCCGUUAGGCCGAA ACGUAGUC
11363





2859
GGAGCAAUC CCUGUGGA
1945
UCCACAGG CUGAUGAGGCCGUUAGGCCGAA AUUGCUCC
11364





2869
CUGUGGAUC UGAAACGG
1946
CCGUUUCA CUGAUGAGGCCGUUAGGCCGAA AUCCACAG
11365





2882
ACGGCGCUU GGACAGCA
1947
UGCUGUCC CUGAUGAGGCCGUUAGGCCGAA AGCGCCGU
11366





2892
GACAGCAUC ACCAGUAG
1948
CUACUGGU CUGAUGAGGCCGUUAGGCCGAA AUGCUGUC
11367





2899
UCACCAGUA GCCAGAGC
1949
GCUCUGGC CUGAUGAGGCCGUUAGGCCGAA ACUGGUGA
11368





2909
CCAGAGCUC AGCCAGCU
1950
AGCUGGCU CUGAUGAGGCCGUUAGGCCGAA AGCUCUGG
11369





2918
AGCCAGCUC UGGAUUUG
1951
CAAAUCCA CUGAUGAGGCCGUUAGGCCGAA AGCUGGCU
11370





2924
CUCUGGAUU UGUGGAGG
1952
COUCCACA CUGAUGAGGCCGUUAGGCCGAA AUCCAGAG
11371





2925
UCUGGAUUU GUGGAGGA
1953
UCCUCCAC CUGAUGAGGCCGUUAGGCCGAA AAUCCAGA
11372





2939
GGAGAAGUC CCUCAGUG
1954
CACUGAGG CUGAUGAGGCCGUUAGGCCGAA ACUUCUCC
11373





2943
AAGUCCCUC AGUGAUGU
1955
ACAUCACU CUGAUGAGGCCGUUAGGCCGAA AGGGACUU
11374





2952
AGUGAUGUA GAAGAAGA
1956
UCUUCUUC CUGAUGAGGCCGUUAGGCCGAA ACAUCACU
11375





2968
AGGAAGCUC CUGAAGAU
1957
AUCUUCAG CUGAUGAGGCCGUUAGGCCGAA AGCUUCCU
11376





2977
CUGAAGAUC UGUAUAAG
1958
CUUAUACA CUGAUGAGGCCGUUAGGCCGAA AUCUUCAG
11377





2981
AGAUCUGUA UAAGGACU
1959
AGUCCUUA CUGAUGAGGCCGUUAGGCCGAA ACAGAUCU
11378





2983
AUCUGUAUA AGGACUUC
1960
GAAGUCCU CUGAUGAGGCCGUUAGGCCGAA AUACAGAU
11379





2990
UAAGGACUU CCUGACCU
1961
AGGUCAGG CUGAUGAGGCCGUUAGGCCGAA AGUCCUUA
11380





2991
AAGGACUUC CUGACCUU
1962
AAGGUCAG CUGAUGAGGCCGUUAGGCCGAA AAGUCCUU
11381





2999
CCUGACCUU GGAGCAUC
1963
GAUGCUCC CUGAUGAGGCCGUUAGGCCGAA AGGUCAGG
11382





3007
UGGAGCAUC UCAUCUGU
1964
ACAGAUGA CUGAUGAGGCCGUUAGGCCGAA AUGCUCCA
11383





3009
GAGCAUCUC AUCUGUUA
1965
UAACAGAU CUGAUGAGGCCGUUAGGCCGAA AGAUGCUC
11384





3012
CAUCUCAUC UGUUACAG
1966
CUGUAACA CUGAUGAGGCCGUUAGGCCGAA AUGAGAUG
11385





3016
UCAUCUGUU ACAGCUUC
1967
GAAGCUGU CUGAUGAGGCCGUUAGGCCGAA ACAGAUGA
11386





3017
CAUCUGUUA CAGCUUCC
1968
GGAAGCUG CUGAUGAGGCCGUUAGGCCGAA AACAGAUG
11387





3023
UUACAGCUU CCAAGUGG
1969
CCACUUGG CUGAUGAGGCCGUUAGGCCGAA AGCUGUAA
11388





3024
UACAGCUUC CAAGUGGC
1970
GCCACUUG CUGAUGAGGCCGUUAGGCCGAA AAGCUGUA
11389





3034
AAGUGGCUA AGGGCAUG
1971
CAUGCCCU CUGAUGAGGCCGUUAGGCCGAA AGCCACUU
11390





3047
CAUGGAGUU CUUGGCAU
1972
AUGCCAAG CUGAUGAGGCCGUUAGGCCGAA ACUCCAUG
11391





3048
AUGGAGGUC UUGGCAUC
1973
GAUGCCAA CUGAUGAGGCCGUUAGGCCGAA AACUCCAU
11392





3050
GGAGUUCUU GGCAUCGC
1974
GCGAUGCC CUGAUGAGGCCGUUAGGCCGAA AGAACUCC
11393





3056
CUUGGCAUC GCGAAAGU
1975
ACUUUCGC CUGAUGAGGCCGUUAGGCCGAA AUGCCAAG
11394





3067
GAAAGUGUA UCCACAGG
1976
CCUGUGGA CUGAUGAGGCCGUUAGGCCGAA ACACUUUC
11395





3069
AAGUGUAUC CACAGGGA
1977
UCCCUGUG CUGAUGAGGCCGUUAGGCCGAA AUACACUU
11396





3094
CACGAAAUA UCCUCUUA
1978
UAAGAGGA CUGAUGAGGCCGUUAGGCCGAA AUUUCCUG
11397





3096
CGAAAUAUC CUCUGAUC
1979
GAUAAGAG CUGAUGAGGCCGUUAGGCCGAA AUAUUUCG
11398





3099
AAUAUCCUC UUAUCGGA
1980
UCCGAUAA CUGAUGAGGCCGUUAGGCCGAA AGGAUAUU
11399





3101
UAUCCUCUU AUCGGAGA
1981
UCUCCGAU CUGAUGAGGCCGUUAGGCCGAA AGAGGAUA
11400





3102
AUCCUOGGA UCGGAGAA
1982
UUCUCCGA CUGAUGAGGCCGUUAGGCCGAA AAGAGGAU
11401





3104
CCUCUUAUC GGAGAAGA
1983
UCUUCUCC CUGAUGAGGCCGUUAGGCCGAA AUAAGAGG
11402





3120
AACGUGGUU AAAAUCUG
1984
CAGAUUUU CUGAUGAGGCCGUUAGGCCGAA ACCACGUU
11403





3121
ACGUGGUUA AAAUCUGU
1985
ACAGAUUU CUGAUGAGGCCGUUAGGCCGAA AACCACGU
11404





3126
GUUAAAAUC UGUGACUU
1986
AAGUCACA CUGAUGAGGCCGUUAGGCCGAA AUUUUAAC
11405





3134
CUGUGACUU UGGCUUGG
1987
CCAAGCCA CUGAUGAGGCCGUUAGGCCGAA AGUCACAG
11406





3135
UGUGACUUU GGCUUGGC
1988
GCCAAGCC CUGAUGAGGCCGUUAGGCCGAA AAGUCACA
11407





3140
CUUUGGCUU GGCCCGGG
1989
CCCGGGCC CUGAUGAGGCCGUUAGGCCGAA AGCCAAAG
11408





3151
CCCGGGAUA UUUAUAAA
1990
UUUAUAAA CUGAUGAGGCCGUUAGGCCGAA AUCCCGGG
11409





3153
CGGGAUAUU UAUAAAGA
1991
UCUUUAUA CUGAUGAGGCCGUUAGGCCGAA AUAUCCCG
11410





3154
GGGAUAUUU AUAAAGAU
1992
AUCUUUAU CUGAUGAGGCCGUUAGGCCGAA AAUAUCCC
11411





3155
GGAUAUUUA UAAAGAUC
1993
GAUCUUUA CUGAUGAGGCCGUUAGGCCGAA AAAUAUCC
11412





3157
AUAUUUAUA AAGAUCCA
1994
UGGAUCUU CUGAUGAGGCCGUUAGGCCGAA AUAAAUAU
11413





3163
AUAAAGAUC CAGAUUAU
1995
AUAAUCUG CUGAUGAGGCCGUUAGGCCGAA AUCUUUAU
11414





3169
AUCCAGAUU AUGUCAGA
1996
UCUGACAU CUGAUGAGGCCGUUAGGCCGAA AUCUGGAU
11415





3170
UCCAGAUUA UGUCAGAA
1997
UUCUGACA CUGAUGAGGCCGUUAGGCCGAA AAUCUGGA
11416





3174
GAUUAUGUC AGAAAAGG
1998
CCUUUUCU CUGAUGAGGCCGUUAGGCCGAA ACAUAAUC
11417





3190
GAGAUGCUC GCCUCCCU
1999
AGGGAGGC CUGAUGAGGCCGUUAGGCCGAA AGCAUCUC
11418





3195
GCUCGCCUC CCUUUGAA
2000
UUCAAAGG CUGAUGAGGCCGUUAGGCCGAA AGGCGAGC
11419





3199
GCCUCCCUU UGAAAUGG
2001
CCAUUUCA CUGAUGAGGCCGUUAGGCCGAA AGGGAGGC
11420





3200
CCUCCCUUU GAAAUGGA
2002
UCCAUUUC CUGAUGAGGCCGUUAGGCCGAA AAGGGAGG
11421





3225
GAAACAAUU UUUGACAG
2003
CUGUCAAA CUGAUGAGGCCGUUAGGCCGAA AUUGUUEU
11422





3226
AAACAAUUU UUGACAGA
2004
UCUGUCAA CUGAUGAGGCCGUUAGGCCGAA AAUUGUUU
11423





3227
AACAAUUUU UGACAGAG
2005
CUCUGUCA CUGAUGAGGCCGUUAGGCCGAA AAAUUGUU
11424





3228
ACAAUUUUU GACAGAGU
2006
ACUCUGUC CUGAUGAGGCCGUUAGGCCGAA AAAAUUGU
11425





3239
CAGAGUGUA CACAAUCC
2007
GGAUUGUG CUGAUGAGGCCGUUAGGCCGAA ACACUCUG
11426





3246
UACACAAUC CAGAGUGA
2008
UCACUCUG CUGAUGAGGCCGUUAGGCCGAA AUUGUGUA
11427





3258
AGUGACGUC UGGUCUUU
2009
AAAGACCA CUGAUGAGGCCGUUAGGCCGAA ACGUCACU
11428





3263
CGUCUGGUC UUUUGGUG
2010
CACCAAAA CUGAUGAGGCCGUUAGGCCGAA ACCAGACG
11429





3265
UCUGGUCUU UUGGUGUU
2011
AACACCAA CUGAUGAGGCCGUUAGGCCGAA AGACCAGA
11430





3266
CUGGUCUUU UGGUGUUU
2012
AAACACCA CUGAUGAGGCCGUUAGGCCGAA AAGACCAG
11431





3267
UGGUCUUUU GGUGUUUU
2013
AAAACACC CUGAUGAGGCCGUUAGGCCGAA AAAGACCA
11432





3273
UUUGGUGUU UUGCUGUG
2014
CACAGCAA CUGAUGAGGCCGUUAGGCCGAA ACACCAAA
11433





3274
UUGGUGUUU UGCUGUGG
2015
CCACAGCA CUGAUGAGGCCGUUAGGCCGAA AACACCAA
11434





3275
UGGUGUUUU GCUGUGGG
2016
CCCACAGC CUGAUGAGGCCGUUAGGCCGAA AAACACCA
11435





3288
UGGGAAAUA UUUUCCUU
2017
AAGGAAAA CUGAUGAGGCCGUUAGGCCGAA AUUUCCCA
11436





3290
GGAAAUAUU UUCCUUAG
2018
CUAAGGAA CUGAUGAGGCCGUUAGGCCGAA AUAUUUCC
11437





3291
GAAAUAUUU UCCUUAGG
2019
CCUAAGGA CUGAUGAGGCCGUUAGGCCGAA AAUAUUUC
11438





3292
AAAUAUUUU CCUUAGGU
2020
ACCUAAGG CUGAUGAGGCCGUUAGGCCGAA AAAUAUUU
11439





3293
AAUAUUUUC CUUAGGUG
2021
CACCUAAG CUGAUGAGGCCGUUAGGCCGAA AAAAUAUU
11440





3296
AUUUUCCUU AGGUGCUU
2022
AAGCACCU CUGAUGAGGCCGUUAGGCCGAA AGGAAAAU
11441





3297
UUUUCCUUA GGUGCUUC
2023
GAAGCACC CUGAUGAGGCCGUUAGGCCGAA AAGGAAAA
11442





3304
UAGGUGCUU CUCCAUAU
2024
AUAUGGAG CUGAUGAGGCCGUUAGGCCGAA AGCACCUA
11443





3305
AGGUGCUUC UCCAUAUC
2025
GAUAUGGA CUGAUGAGGCCGUUAGGCCGAA AAGCACCU
11444





3307
GUGCUUCUC CAUAUCCU
2026
AGGAUAUG CUGAUGAGGCCGUUAGGCCGAA AGAAGCAC
11445





3311
UUCUCCAUA UCCUGGGG
2027
CCCCAGGA CUGAUGAGGCCGUUAGGCCGAA AUGGAGAA
11446





3313
CUCCAUAUC CUGGGGUA
2028
UACCCCAG CUGAUGAGGCCGUUAGGCCGAA AUAUGGAG
11447





3321
CCUGGGGUA AAGAUUGA
2029
UCAAUCUU CUGAUGAGGCCGUUAGGCCGAA ACCCCAGG
11448





3327
GUAAAGAUU GAUGAAGA
2030
UCUUCAUC CUGAUGAGGCCGUUAGGCCGAA AUCUUUAC
11449





3338
UGAAGAAUU UUGUAGGC
2031
GCCUACAA CUGAUGAGGCCGUUAGGCCGAA AUUCUUCA
11450





3339
GAAGAAUUU UGUAGGCG
2032
CGCCUACA CUGAUGAGGCCGUUAGGCCGAA AAUUCUUC
11451





3340
AAGAAUUUU GUAGGCGA
2033
UCGCCUAC CUGAUGAGGCCGUUAGGCCGAA AAAUUCUU
11452





3343
AAUUUUGUA GGCGAUUG
2034
CAAUCGCC CUGAUGAGGCCGUUAGGCCGAA ACAAAAUU
11453





3350
UAGGCGAUU GAAAGAAG
2035
CUUCUUUC CUGAUGAGGCCGUUAGGCCGAA AUCGCCUA
11454





3364
AAGGAACUA GAAUGAGG
2036
CCUCAUUC CUGAUGAGGCCGUUAGGCCGAA AGUUCCUU
11455





3382
CCCCUGAUU AUACUACA
2037
UGUAGUAU CUGAUGAGGCCGUUAGGCCGAA AUCAGGGG
11456





3383
CCCUGAUUA UACUACAC
2038
GUGUAGUA CUGAUGAGGCCGUUAGGCCGAA AAUCAGGG
11457





3385
CUGAUUAUA CUACACCA
2039
UGGUGUAG CUGAUGAGGCCGUUAGGCCGAA AUAAUCAG
11458





3388
AUUAUACUA CACCAGAA
2040
UUCUGGUG CUGAUGAGGCCGUUAGGCCGAA AGUAUAAU
11459





3401
AGAAAUGUA CCAGACCA
2041
UGGUCUGG CUGAUGAGGCCGUUAGGCCGAA ACAUUUCU
11460





3439
AGCCCAGUC AGAGACCC
2042
GGGUCUCU CUGAUGAGGCCGUUAGGCCGAA ACUGGGCU
11461





3452
ACCCACGUU UUCAGAGU
2043
ACUCUGAA CUGAUGAGGCCGUUAGGCCGAA ACGUGGGU
11462





3453
CCCACGUUU UCAGAGUU
2044
AACUCUGA CUGAUGAGGCCGUUAGGCCGAA AACGUGGG
11463





3454
CCACGUUUU CAGAGUUG
2045
CAACUCUG CUGAUGAGGCCGUUAGGCCGAA AAACGUGG
11464





3455
CACGUUUUC AGAGUUGG
2046
CCAACUCU CUGAUGAGGCCGUUAGGCCGAA AAAACGUG
11465





3461
UUCAGAGUU GGUGGAAC
2047
GUUCCACC CUGAUGAGGCCGUUAGGCCGAA ACUCUGAA
11466





3472
UGGAACAUU UGGGAAAU
2048
AUUUCCCA CUGAUGAGGCCGUUAGGCCGAA AUGUUCCA
11467





3473
GGAACAUUU GGGAAAUC
2049
GAUUUCCC CUGAUGAGGCCGUUAGGCCGAA AAUGUUCC
11468





3481
UGGGAAAUC UCUUGCAA
2050
UUGCAAGA CUGAUGAGGCCGUUAGGCCGAA AUUUCCCA
11469





3483
GGAAAUCUC UUGCAAGC
2051
GCUUGCAA CUGAUGAGGCCGUUAGGCCGAA AGAUUUCC
11470





3485
AAAUCUCUU GCAAGCUA
2052
UAGCUUGC CUGAUGAGGCCGUUAGGCCGAA AGAGAUUU
11471





3493
UGCAAGCUA AUGGUCAG
2053
CUGAGCAU CUGAUGAGGCCGUUAGGCCGAA AGCUUGCA
11472





3499
CUAAUGCUC AGCAGGAU
2054
AUCCUGCU CUGAUGAGGCCGUUAGGCCGAA AGCAUUAG
11473





3518
CAAAGACUA CAUUGUUC
2055
GAACAAUG CUGAUGAGGCCGUUAGGCCGAA AGUCUUUG
11474





3522
GACUACAUU GUUCUUCC
2056
GGAAGAAC CUGAUGAGGCCGUUAGGCCGAA AUGUAGUC
11475





3525
UACAUUGUU CUUCCGAU
2057
AUCGGAAG CUGAUGAGGCCGUUAGGCCGAA ACAAUGUA
11476





3526
ACAUUGUUC UUCCGAUA
2058
UAUCGGAA CUGAUGAGGCCGUUAGGCCGAA AACAAUGU
11477





3528
AUUGUUCUU CCGAUAUC
2059
GAUAUCGG CUGAUGAGGCCGUUAGGCCGAA AGAACAAU
11478





3529
UUGUUCUUC CGAUAUCA
2060
UGAUAUCG CUGAUGAGGCCGUUAGGCCGAA AAGAACAA
11479





3534
CUUCCGAUA UCAGAGAC
2061
GUCUCUGA CUGAUGAGGCCGUUAGGCCGAA AUCGGAAG
11480





3536
UCCGAUAUC AGAGACUU
2062
AAGUCUCU CUGAUGAGGCCGUUAGGCCGAA AUAUCGGA
11481





3544
CAGAGACUU UGAGCAUG
2063
CAUGOUCA CUGAUGAGGCCGUUAGGCCGAA AGUCUCUG
11482





3545
AGAGACUUU GAGCAUGG
2064
CCAUGCUC CUGAUGAGGCCGUUAGGCCGAA AAGUCUCU
11483





3562
AAGAGGAUU CUGGACUC
2065
GAGUCCAG CUGAUGAGGCCGUUAGGCCGAA AUCCUCUU
11484





3563
AGAGGAUUC UGGACUCU
2066
AGAGUCCA CUGAUGAGGCCGUUAGGCCGAA AAUCCUCU
11485





3570
UCUGGACUC UCUCUGCC
2067
GGCAGAGA CUGAUGAGGCCGUUAGGCCGAA AGUCCAGA
11486





3572
UGGACUCUC UCUGCCUA
2068
UAGGCAGA CUGAUGAGGCCGUUAGGCCGAA AGAGUCCA
11487





3574
GACUCUCUC UGCCUACC
2069
GGUAGGCA CUGAUGAGGCCGUUAGGCCGAA AGAGAGUC
11488





3580
CUCUGCCUA CCUCACCU
2070
AGGUGAGG CUGAUGAGGCCGUUAGGCCGAA AGGCAGAG
11489





3584
GCCUACCUC ACCUGUUU
2071
AAACAGGU CUGAUGAGGCCGUUAGGCCGAA AGGUAGGC
11490





3591
UCACCUGUU UCCUGUAU
2072
AUACAGGA CUGAUGAGGCCGUUAGGCCGAA ACAGGUGA
11491





3592
CACCUGUUU CCUGUAUG
2073
CAUACAGG CUGAUGAGGCCGUUAGGCCGAA AACAGGUG
11492





3593
ACCUGUUUC CUGUAUGG
2074
CCAUACAG CUGAUGAGGCCGUUAGGCCGAA AAACAGGU
11493





3598
UUUCCUGUA UGGAGGAG
2075
CUCCUCCA CUGAUGAGGCCGUUAGGCCGAA ACAGGAAA
11494





3615
GAGGAAGUA UGUGACCC
2076
GGGUCACA CUGAUGAGGCCGUUAGGCCGAA ACUUCCUC
11495





3629
CCCCAAAUU CCAUUAUG
2077
CAUAAUGG CUGAUGAGGCCGUUAGGCCGAA AUUUGGGG
11496





3630
CCCAAAUUC CAUUAUGA
2078
UCAUAAUG CUGAUGAGGCCGUUAGGCCGAA AAUUUGGG
11497





3634
AAUUCCAUU AUGACAAC
2079
GUUGUCAU CUGAUGAGGCCGUUAGGCCGAA AUGGAAUU
11498





3635
AUUCCAUUA UGACAACA
2080
UGUUGUCA CUGAUGAGGCCGUUAGGCCGAA AAUGGAAU
11499





3654
GCAGGAAUC AGUCAGUA
2081
UACUGACU CUGAUGAGGCCGUUAGGCCGAA AUUCCUGC
11500





3658
GAAUCAGUC AGUAUCUG
2082
CAGAUACU CUGAUGAGGCCGUUAGGCCGAA ACUGAUUC
11501





3662
CAGUCAGUA UCUGCAGA
2083
UCUGCAGA CUGAUGAGGCCGUUAGGCCGAA ACUGACUG
11502





3664
GUCAGUAUC UGCAGAAC
2084
GUUCUGCA CUGAUGAGGCCGUUAGGCCGAA AUACUGAC
11503





3676
AGAACAGUA AGCGAAAG
2085
CUUUCGCU CUGAUGAGGCCGUUAGGCCGAA ACUGUUCU
11504





3702
GUGAGUGUA AAAACAUU
2086
AAUGUUUU CUGAUGAGGCCGUUAGGCCGAA ACACUCAC
11505





3710
AAAPACAUU UGAAGAUA
2087
UAUCUUCA CUGAUGAGGCCGUUAGGCCGAA AUGUUUUU
11506





3711
AAAACAUUU GAAGAUAU
2088
AUAUCUUC CUGAUGAGGCCGUUAGGCCGAA AAUGUUUU
11507





3718
UUGAAGAUA UCCCGUUA
2089
UAACGGGA CUGAUGAGGCCGUUAGGCCGAA AUCUUCAA
11508





3720
GAAGAUAUC CCGUUAGA
2090
UCUAACGG CUGAUGAGGCCGUUAGGCCGAA AUAUCUUC
11509





3725
UAUCCCGUU AGAAGAAC
2091
GUUCUUCU CUGAUGAGGCCGUUAGGCCGAA ACGGGAUA
11510





3726
AUCCCGUUA GAAGAACC
2092
GGUUCUUC CUGAUGAGGCCGUUAGGCCGAA AACGGGAU
11511





3741
CCAGAAGUA AAAGUAAU
2093
AUUACUUU CUGAUGAGGCCGUUAGGCCGAA ACUUCUGG
11512





3747
GUAAAAGUA AUCCCAGA
2094
UCUGGGAU CUGAUGAGGCCGUUAGGCCGAA ACUUUUAC
11513





3750
AAAGUAAUC CCAGAUGA
2095
UCAUCUGG CUGAUGAGGCCGUUAGGCCGAA AUUACUUU
11514





3778
ACAGUGGUA UGGUUCUU
2096
AAGAACCA CUGAUGAGGCCGUUAGGCCGAA ACCACUGU
11515





3783
GGUAUGGUU CUUGCCUC
2097
GAGGCAAG CUGAUGAGGCCGUUAGGCCGAA ACCAUACC
11516





3784
GUAUGGUUC UUGCCUCA
2098
UGAGGCAA CUGAUGAGGCCGUUAGGCCGAA AACCAUAC
11517





3786
AUGGUUCUU GCCUCAGA
2099
UCUGAGGC CUGAUGAGGCCGUUAGGCCGAA AGAACCAU
11518





3791
UCUUGCCUC AGAAGAGC
2100
GCUCUUCU CUGAUGAGGCCGUUAGGCCGAA AGGCAAGA
11519





3808
UGAAAACUU UGGAAGAC
2101
GUCUUCCA CUGAUGAGGCCGUUAGGCCGAA AGUUUUCA
11520





3809
GAAAACUUU GGAAGACA
2102
UGUCUUCC CUGAUGAGGCCGUUAGGCCGAA AAGUUUUC
11521





3827
AACCAAAUU AUCUCCAU
2103
AUGGAGAU CUGAUGAGGCCGUUAGGCCGAA AUUUGGUU
11522





3828
ACCAAAUUA UCUCCAUC
2104
GAUGGAGA CUGAUGAGGCCGUUAGGCCGAA AAUUUGGU
11523





3830
CAAAUUAUC UCCAUCUU
2105
AAGAUGGA CUGAUGAGGCCGUUAGGCCGAA AUAAUUUG
11524





3832
AAUUAUCUC CAUCUTUU
2106
AAAAGAUG CUGAUGAGGCCGUUAGGCCGAA AGAUAAUU
11525





3836
AUCUCCAUC UUUUGGUG
2107
CACCAAAA CUGAUGAGGCCGUUAGGCCGAA AUGGAGAU
11526





3838
CUCCAUCUU UUGGUGGA
2108
UCCACCAA CUGAUGAGGCCGUUAGGCCGAA AGAUGGAG
11527





3839
UCCAUCUUU UGGUGGAA
2109
UUCCACCA CUGAUGAGGCCGUUAGGCCGAA AAGAUGGA
11528





3840
CCAUCUUUU GGUGGAAU
2110
AUUCCACC CUGAUGAGGCCGUUAGGCCGAA AAAGAUGG
11529





3872
CAGGGAGUC UGUGGCAU
2111
AUGCCACA CUGAUGAGGCCGUUAGGCCGAA ACUCCCUG
11530





3881
UGUGGCAUC UGAAGGCU
2112
AGCCUUCA CUGAUGAGGCCGUUAGGCCGAA AUGCCACA
11531





3890
UGAAGGCUC AAACCAGA
2113
UCUGGUUU CUGAUGAGGCCGUUAGGCCGAA AGCCUUCA
11532





3908
AAGCGGCUA CCAGUCCG
2114
CGGACUGG CUGAUGAGGCCGUUAGGCCGAA AGCCGCUU
11533





3914
CUACCAGUC CGGAUAUC
2115
GAUAUCCG CUGAUGAGGCCGUUAGGCCGAA ACUGGUAG
11534





3920
GUCCGGAUA UCACUCCO
2116
CGGAGUGA CUGAUGAGGCCGUUAGGCCGAA AUCCGGAC
11535





3922
CCGGAUAUC ACUCCGAU
2117
AUCGGAGU CUGAUGAGGCCGUUAGGCCGAA AUAUCCGG
11536





3926
AUAUCACUC CGAUGACA
2118
UGUCAUCG CUGAUGAGGCCGUUAGGCCGAA AGUGAUAU
11537





3950
CACCGUGUA CUCCAGUG
2119
CACUGGAG CUGAUGAGGCCGUUAGGCCGAA ACACGGUG
11538





3953
CGUGUACUC CAGUGAGG
2120
CCUCACUG CUGAUGAGGCCGUUAGGCCGAA AGUACACG
11539





3972
GCAGAACUU UUAAAGCU
2121
AGCUUUAA CUGAUGAGGCCGUUAGGCCGAA AGUUCUGC
11540





3973
CAGAACUUU UAAAGCUG
2122
CAGCUUUA CUGAUGAGGCCGUUAGGCCGAA AAGUUCUG
11541





3974
AGAACUUUU AAAGCUGA
2123
UCAGCUUU CUGAUGAGGCCGUUAGGCCGAA AAAGUUCU
11542





3975
GAACUUUUA AAGCUGAU
2124
AUCAGCUU CUGAUGAGGCCGUUAGGCCGAA AAAAGUUC
11543





3984
AAGCUGAUA GAGAUUGG
2125
CCAAUCUC CUGAUGAGGCCGUUAGGCCGAA AUCAGCUU
11544





3990
AUAGAGAUU GGAGUGCA
2126
UGCACUCC CUGAUGAGGCCGUUAGGCCGAA AUCUCUAU
11545





4006
AAACCGGUA GCACAGCC
2127
GGCUGUGC CUGAUGAGGCCGUUAGGCCGAA ACCGGUUU
11546





4020
GCCCAGAUU CUCCAGCC
2128
GGCUGGAG CUGAUGAGGCCGUUAGGCCGAA AUCUGGGC
11547





4021
CCCAGAUUC UCCAGCCU
2129
AGGCUGGA CUGAUGAGGCCGUUAGGCCGAA AAUCUGGG
11548





4023
CAGAUUCUC CAGCCUGA
2130
UCAGGCUG CUGAUGAGGCCGUUAGGCCGAA AGAAUCUG
11549





4052
ACUGAGCUC UCCUCCUG
2131
CAGGAGGA CUGAUGAGGCCGUUAGGCCGAA AGCUCAGU
11550





4054
UGAGCUCUC CUCCUGUU
2132
AACAGGAG CUGAUGAGGCCGUUAGGCCGAA AGAGCUCA
11551





4057
GCUCUCCUC CUGUUUAA
2133
UUAAACAG CUGAUGAGGCCGUUAGGCCGAA AGGAGAGC
11552





4062
CCUCCUGUU UAAAAGGA
2134
UCCUUUUA CUGAUGAGGCCGUUAGGCCGAA ACAGGAGG
11553





4063
CUCCUGUUU AAAAGGAA
2135
UUCCUUUU CUGAUGAGGCCGUUAGGCCGAA AACAGGAG
11554





4064
UCCUGUUUA AAAGGAAG
2136
CUUCCUUU CUGAUGAGGCCGUUAGGCCGAA AAACAGGA
11555





4076
GGAAGCAUC CACACCCC
2137
GGGGUGUG CUGAUGAGGCCGUUAGGCCGAA AUGCUUCC
11556





4089
CCCCAACUC CCGGACAU
2138
AUGUCCGG CUGAUGAGGCCGUUAGGCCGAA AGUUGGGG
11557





4098
CCGGACAUC ACAUGAGA
2139
UCUCAUGU CUGAUGAGGCCGUUAGGCCGAA AUGUCCGG
11558





4110
UGAGAGGUC UGCUCAGA
2140
UCUGAGCA CUGAUGAGGCCGUUAGGCCGAA ACCUCUCA
11559





4115
GGUCUGCUC AGAUUUUG
2141
CAAAAUCU CUGAUGAGGCCGUUAGGCCGAA AGCAGACC
11560





4120
GCUCAGAUU UUGAAGUG
2142
CACUUCAA CUGAUGAGGCCGUUAGGCCGAA AUCUGAGC
11561





4121
CUCAGAUUU UGAAGUGU
2143
ACACUUCA CUGAUGAGGCCGUUAGGCCGAA AAUCUGAG
11562





4122
UCAGAUUUU GAAGUGUU
2144
AACACUUC CUGAUGAGGCCGUUAGGCCGAA AAAUCUGA
11563





4130
UGAAGUGUU GUUCUUUC
2145
GAAAGAAC CUGAUGAGGCCGUUAGGCCGAA ACACUUCA
11564





4133
AGUGUUGUU CUUUCCAC
2146
GUGGAAAG CUGAUGAGGCCGUUAGGCCGAA ACAACACU
11565





4134
GUGUUGUUC UUUCCACC
2147
GGUGGAAA CUGAUGAGGCCGUUAGGCCGAA AACAACAC
11566





4136
GUUGUUCUU UCCACCAG
2148
CUGGUGGA CUGAUGAGGCCGUUAGGCCGAA AGAACAAC
11567





4137
UUGUUCUUU CCACCAGC
2149
GCUGGUGG CUGAUGAGGCCGUUAGGCCGAA AAGAACAA
11568





4138
UGUUCUUUC CACCAGCA
2150
UGCUGGUG CUGAUGAGGCCGUUAGGCCGAA AAAGAACA
11569





4153
CAGGAAGUA GCCGCAUU
2151
AAUGCGGC CUGAUGAGGCCGUUAGGCCGAA ACUUCCUG
11570





4161
AGCCGCAUU UGAUUUUU
2152
GAAAAUCA CUGAUGAGGCCGUUAGGCCGAA AUGCGGCU
11571





4162
GCCGCAUUU GAUUUUCA
2153
UGAAAAUC CUGAUGAGGCCGUUAGGCCGAA AAUGCGGC
11572





4166
CAUUUGAUU UUCAUUUC
2154
GAAAUGAA CUGAUGAGGCCGUUAGGCCGAA AUCAAAUG
11573





4167
AUUUGAUUU UCAUUUCG
2155
CGAAAUGA CUGAUGAGGCCGUUAGGCCGAA AAUCAAAU
11574





4168
UUUGAUUUU CAUUUCGA
2156
UCGAAAUG CUGAUGAGGCCGUUAGGCCGAA AAAUCAAA
11575





4169
UUGAUUUUU AUUUUGAC
2157
GUCGAAAU CUGAUGAGGCCGUUAGGCCGAA AAAAUCAA
11576





4172
AUUUUCAUU UCGACAAC
2158
GUUGUCGA CUGAUGAGGCCGUUAGGCCGAA AUGAAAAU
11577





4173
UUUUCAUUU CGACAACA
2159
UGUUGUCG CUGAUGAGGCCGUUAGGCCGAA AAUGAAAA
11578





4174
UUUCAUUUC GACAACAG
2160
CUGUUGUC CUGAUGAGGCCGUUAGGCCGAA AAAUGAAA
11579





4194
AAGGACCUC GGACUGCA
2161
UGCAGUCC CUGAUGAGGCCGUUAGGCCGAA AGGUCCUU
11580





4214
AGCCAGCUC UUCUAGGC
2162
GCCUAGAA CUGAUGAGGCCGUUAGGCCGAA AGCUGGCU
11581





4216
CCAGCUCUU CUAGGCUU
2163
AAGCCUAG CUGAUGAGGCCGUUAGGCCGAA AGAGCUGG
11582





4217
CAGCUCUUC UAGGCUUG
2164
CAAGCCUA CUGAUGAGGCCGUUAGGCCGAA AAGAGCUG
11583





4219
GCUCUUCUA GGCUUGUG
2165
CACAAGCC CUGAUGAGGCCGUUAGGCCGAA AGAAGAGC
11584






Where “X” represents stem II region of a HH ribozyme (Hertel et al., 1992 Nucleic Acids Res. 20 3252).




The length of stem II maybe 2 base-pairs.




Underlined region can be any X sequence or linker, as described herein.








[0344]

8






TABLE V










Human KDR VEGF Receptor-Hairpin Ribozyme and Substrate Sequences















Seq

Seq





ID

ID


Pos
Substrate
No
Hairpin Ribozyme Sequence
No















11
AGGUGCU GCU GGCCGUCG
2166
CGACGGCC AGAA GCACCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11585






18
GCUGGCC GUC GCCCUGUG
2167
CACAGGGC AGAA GCCAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11586





51
CCGGGCC GCC UCUGUGGG
2168
CCCACAGA AGAA GCCCGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11587





86
UUGAUCU CCC CAGGCUCA
2169
UGAGCCUG AGAA GAUCAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11588





318
GGAAACU GAC UUGGCCUC
2170
GAGGCCAA AGAA GUUUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11589





358
GAUUACA GAU CUCCAUUU
2171
AAAUGGAG AGAA GUAAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11590





510
UGUUCCU GAU GGUAACAG
2172
CUGUUACC AGAA GGAACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11591





623
GUUACCA GUC UAUUAUGU
2173
ACAUAAUA AGAA GGUAAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11592





683
UGAGUCC GUC UCAUGGAA
2174
UUCCAUGA AGAA CACUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11593





705
ACUAUCU GUU GGAGAAAA
2175
UUUUCUCC AGAA GAUAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11594





833
AAACCCA GUC UGGGAGUG
2176
CACUCCCA AGAA GGGUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11595





932
GUGGGCU GAU GACCAACA
2177
UCUUGGUC AGAA GCCCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11596





1142
AUGUACU GAC GAUUAUGG
2178
CCAUAAUC AGAA GUACAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11597





1259
CACCCCA GAU UGGUGAGA
2179
UCUCACCA AGAA GGGGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11598





1332
AUGUACG GUC UAUGCCAU
2180
AUGGCAUA AGAA GUACAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11599





1376
AUUGGCA GUU GGAGGAAG
2181
CUUCCUCC AGAA GCCAAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11600





1413
CCAAGCU GUC UCAGUGAC
2182
GUCACUGA AGAA GCUUGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11601





1569
UGUGUCA GCU UUGUACAA
2183
UUGUACAA AGAA GACACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11602





1673
ACAUGCA GCC CACUGAGC
2184
GCUCAGUG AGAA GCAUGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11603





1717
GCAGACA GAU CUACGUUU
2185
AAACGUAG AGAA GUCUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11604





1760
GCCCACA CCC UCUGCCAA
2186
UUGGCAGA AGAA GUGGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11605





1797
CACACCU GUU UGCAAGAA
2187
UUCUUGCA AGAA GGUGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11606





1918
UAUGUCU GCC UUGCUCAA
2188
UUGAGCAA AGAA GACAUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11607





1967
UCAGGCA GCU CACAGUCC
2189
GGACUGUG AGAA GCCUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11608





1974
GCUCACA GUC CUAGAGCG
2190
CGCUCUAG AGAA GUGAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11609





2021
AGAAUCA GAC GACAAGUA
2191
UACUUGUC AGAA GAUUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11610





2084
CUCCACA GAU CAUGUGGU
2192
ACCACAUG AGAA GUGGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11611





2418
GGAUCCA GAU GAACUCCC
2193
GGGAGUUC AGAA GGAUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11612





2453
AACGACU GCC UUAUGAUG
2194
CAUCAUAA AGAA GUCGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11613





2492
GAGACCG GCU GAACCUAG
2195
CUAGGUUC AGAA GGUCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11614





2547
UGAAGCA GAU GCCUUUGG
2196
CCAAAGGC AGAA GCUUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11615





2765
GAAACCU CUC CACUUACC
2197
GGUAAGUG AGAA GGUUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11616





2914
UCAGCCA GCU CUGGAUUU
2198
AAAUCCAG AGAA GGCUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11617





2993
ACUUCCU GAC CUUGGAGC
2199
GCUCCAAG AGAA GGAAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11618





3019
UGUUACA GCU UCCAAGUG
2200
CACUUGGA AGAA GUAACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11619





3165
AGAUCCA GAU UAUGUCAG
2201
CUGACAUA AGAA GGAUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11620





3378
GGCCCCU GAU UAUACUAC
2202
GUAGUAUA AGAA GGGGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11621





3404
UGUACCA GAC CAUGCUGG
2203
CCAGCAUG AGAA GGUACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11622





3418
CUGGACU GCU GGCACGGG
2204
CCCGUGCC AGAA GUCCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11623





3575
UCUCUCU GCC UACCUCAC
2205
GUGAGGUA AGAA GAGAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11624





3588
CUCACCU GUU UCCUGUAU
2206
AUACAGGA AGAA GGUGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11625





3689
AGAGCCG GCC UGUGAGUG
2207
CACUCACA AGAA GGCUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11626





3753
AAUCCCA GAU GACAACCA
2208
UGGUUGUC AGAA GGGAUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11627





3764
ACAACCA GAC GGACAGUG
2209
CACUGUCC AGAA GGUUGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11628





3911
GCUACCA GUC CGGAUAUC
2210
GAUAUCCG AGAA GGUAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11629





3927
UCACUCC GAU GACACAGA
2211
UCUGUGUC AGAA GAGUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11630





4011
UAGCACA GCC CAGAUUCU
2212
AGAAUCUG AGAA GUGCUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11631





4016
CAGCCCA GAU UCUCCAGC
2213
GCUGGAGA AGAA GGGCUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11632





4025
UUCUCCA GCC UGACACGG
2214
CCGUGUCA AGAA GGAGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11633





4059
UCCUCCU GUU UAAAAGGA
2215
UCCUUUUA AGAA GGAGGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11634





4111
GAGGUCU GCU CAGAUUUU
2216
AAAAUCUG AGAA GACCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11635





4116
CUGCUCA GAU UUUGAAGU
2217
ACUUCAAA AGAA GAGCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11636





4195
GACCUCG GAC UGCAGGGA
2218
UCCCUGCA AGAA GAGGUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11637





4210
GGAGCCA GCU CUUCUAGG
2219
CCUAGAAG AGAA GGCUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11638










[0345]

9






TABLE VI








+HZ,1 Mouse flk-1 VEGF Receptor-Hammerhead Ribozyme and Substrate Sequence




















Seq

Seq





ID

ID


Pos
Substrate
No
HH Ribozyme Sequence
No















13
GGGCGAAUU GGGUACGG
2220
CCGUACCC CUGAUGAGGCCGUUAGGCCGAA AUUCGCCC
11639






18
AAUUGGGUA CGGGACCC
2221
GGGUCCCG CUGAUGAGGCCGUUAGGCCGAA ACCCAAUU
11640





31
ACCCCCCUC GAGGUCGA
2222
UCGACCUC CUGAUGAGGCCGUUAGGCCGAA AGGGGGGU
11641





37
CUCGAGGUC GACGGUAU
2223
AUACCGUC CUGAUGAGGCCGUUAGGCCGAA ACCUCGAG
11642





44
UCGACGGUA UCGAUAAG
2224
CUUAUCGA CUGAUGAGGCCGUUAGGCCGAA ACCGUCGA
11643





46
GACGGUAUC GAUAAGCU
2225
AGCUUAUC CUGAUGAGGCCGUUAGGCCGAA AUACCGUC
11644





50
GUAUCGAUA AGCUUGAU
2226
AUCAAGCU CUGAUGAGGCCGUUAGGCCGAA AUCGAUAC
11645





55
GAUAAGCUU GAUAUCGA
2227
UCGAUAUC CUGAUGAGGCCGUUAGGCCGAA AGCUUAUC
11646





59
AGCUUGAUA UCGAAUUC
2228
GAAUUCGA CUGAUGAGGCCGUUAGGCCGAA AUCAAGCU
11647





61
CUUGAUAUC GAAUUCGG
2229
CCGAAUUC CUGAUGAGGCCGUUAGGCCGAA AUAUCAAG
11648





66
UAUCGAAUU CGGGCCCA
2230
UGGGCCCG CUGAUGAGGCCGUUAGGCCGAA AUUCGAUA
11649





67
AUCGAAUUC GGGCCCAG
2231
CUGGGCCC CUGAUGAGGCCGUUAGGCCGAA AAUUCGAU
11650





83
GACUGUGUC CCGCAGCC
2232
GGCUGCGG CUGAUGAGGCCGUUAGGCCGAA ACACAGUC
11651





97
GCCGGGAUA ACCUGGCU
2233
AGCCAGGU CUGAUGAGGCCGUUAGGCCGAA AUCCCGGC
11652





114
GACCCGAUU CCGCGGAC
2234
GUCCGCGG CUGAUGAGGCCGUUAGGCCGAA AUCGGGUC
11653





115
ACCCGAUUC CGCGGACA
2235
UGUCCGCG CUGAUGAGGCCGUUAGGCCGAA AAUCGGGU
11654





169
CCCGCGCUC UCCCCGGU
2236
ACCGGGGA CUGAUGAGGCCGUUAGGCCGAA AGCGCGGG
11655





171
CGCGCUCUC CCCGGUCU
2237
AGACCGGG CUGAUGAGGCCGUUAGGCCGAA AGAGCGCG
11656





178
UCCCCGGUC UUGCGCUG
2238
CAGCGCAA CUGAUGAGGCCGUUAGGCCGAA ACCGGGGA
11657





180
CCCGGUCUU GCGCUGCG
2239
CGCAGCGC CUGAUGAGGCCGUUAGGCCGAA AGACCGGG
11658





197
GGGGCCAUA CCGCCUCU
2240
AGAGGCGG CUGAUGAGGCCGUUAGGCCGAA AUGGCCCC
11659





204
UACCGCCUC UGUGACUU
2241
AAGUCACA CUGAUGAGGCCGUUAGGCCGAA AGGCGGUA
11660





212
CUGUGACUU CUUUGCGG
2242
CCGCAAAG CUGAUGAGGCCGUUAGGCCGAA AGUCACAG
11661





213
UGUGACUUC UUUGCGGG
2243
CCCGCAAA CUGAUGAGGCCGUUAGGCCGAA AAGUCACA
11662





215
UGACUUCUU UGCGGGCC
2244
GGCCCGCA CUGAUGAGGCCGUUAGGCCGAA AGAAGUCA
11663





216
GACUUCUUU GCGGGCCA
2245
UGGCCCGC CUGAUGAGGCCGUUAGGCCGAA AAGAAGUC
11664





241
GAAGGAGUC UGUGCCUG
2246
CAGGCACA CUGAUGAGGCCGUUAGGCCGAA ACUCCUUC
11665





262
ACUGGGCUC UGUGCCCA
2247
UGGGCACA CUGAUGAGGCCGUUAGGCCGAA AGCCCAGU
11666





306
GCGCUGCUA GCUGUCGC
2248
GCGACAGC CUGAUGAGGCCGUUAGGCCGAA AGCAGCGC
11667





312
CUAGCUGUC GCUCUGUG
2249
CACAGAGC CUGAUGAGGCCGUUAGGCCGAA ACAGCUAG
11668





316
CUGUCGCUC UGUGGUUC
2250
GAACCACA CUGAUGAGGCCGUUAGGCCGAA AGCGACAG
11669





323
UCUGUGGUU CUGCGUGG
2251
CCACGCAG CUGAUGAGGCCGUUAGGCCGAA ACCACAGA
11670





324
CUGUGGUUC UGCGUGGA
2252
UCCACGCA CUGAUGAGGCCGUUAGGCCGAA AACCACAG
11671





347
AGCCGCCUC UGUGGGUU
2253
AACCCACA CUGAUGAGGCCGUUAGGCCGAA AGGCGGCU
11672





355
CUGUGGGUU UGACUGGC
2254
GCCAGUCA CUGAUGAGGCCGUUAGGCCGAA ACCCACAG
11673





356
UGUGGGUUU GACUGGCG
2255
CGCCAGUC CUGAUGAGGCCGUUAGGCCGAA AACCCACA
11674





367
CUGGCGAUU UUCUCCAU
2256
AUGGAGAA CUGAUGAGGCCGUUAGGCCGAA AUCGCCAG
11675





368
UGGCGAUUU UCUCCAUC
2257
GAUGGAGA CUGAUGAGGCCGUUAGGCCGAA AAUCGCCA
11676





369
GGCGAUUUU CUCCAUCC
2258
GGAUGGAG CUGAUGAGGCCGUUAGGCCGAA AAAUCGCC
11677





370
GCGAUUUUC UCCAUCCC
2259
GGGAUGGA CUGAUGAGGCCGUUAGGCCGAA AAAAUCGC
11678





372
GAUUUUCUC CAUCCCCC
2260
GGGGGAUG CUGAUGAGGCCGUUAGGCCGAA AGAAAAUC
11679





376
UUCUCCAUC CCCCCAAG
2261
CUUGGGGG CUGAUGAGGCCGUUAGGCCGAA AUGGAGAA
11680





387
CCCAAGCUC AGCACACA
2262
UGUGUGCU CUGAUGAGGCCGUUAGGCCGAA AGCUUGGG
11681





405
AAAGACAUA CUGACAAU
2263
AUUGUCAG CUGAUGAGGCCGUUAGGCCGAA AUGUCUUU
11682





414
CUGACAAUU UUGGCAAA
2264
UUUGCCAA CUGAUGAGGCCGUUAGGCCGAA AUUGUCAG
11683





415
UGACAAUUU UGGCAAAU
2265
AUCUGCCA CUGAUGAGGCCGUUAGGCCGAA AAUUGUCA
11684





416
GACAAUUUU GGCAAAUA
2266
UAUUUGCC CUGAUGAGGCCGUUAGGCCGAA AAAUUGUC
11685





424
UGGCAAAUA CAACCCUU
2267
AAGGGUUG CUGAUGAGGCCGUUAGGCCGAA AUUUGCCA
11686





432
ACAACCCUU CAGAUUAC
2268
GUAAUCUG CUGAUGAGGCCGUUAGGCCGAA AGGGUUGU
11687





433
CAACCCUUC AGAUUACU
2269
AGUAAUCU CUGAUGAGGCCGUUAGGCCGAA AAGGGUUG
11688





438
CUUCAGAUU ACUUGCAG
2270
CUGCAAGU CUGAUGAGGCCGUUAGGCCGAA AUCUGAAG
11689





439
UUCAGAUUA CUUGCAGG
2271
CCUGCAAG CUGAUGAGGCCGUUAGGCCGAA AAUCUGAA
11690





442
AGAUUACUU GCAGGGGA
2272
UCCCCUGC CUGAUGAGGCCGUUAGGCCGAA AGUAAUCU
11691





471
GACUGGCUU UGGCCCAA
1534
UUGGGCCA CUGAUGAGGCCGUUAGGCCGAA AGCCAGUC
10953





472
ACUGGCUUU GGCCCAAU
1535
AUUGGGCC CUGAUGAGGCCGUUAGGCCGAA AAGCCAGU
10954





484
CCAAUGCUC AGCGUGAU
2273
AUCACGCU CUGAUGAGGCCGUUAGGCCGAA AGCAUUGG
11692





493
AGCGUGAUU CUGAGGAA
2274
DUCCUCAG CUGAUGAGGCCGUUAGGCCGAA AUCACGCU
11693





494
GCGUGAUUC UGAGGAAA
2275
UUUCCUCA CUGAUGAGGCCGUUAGGCCGAA AAUCACGC
11694





507
GAAAGGGUA UUGGUGAC
2276
GUCACCAA CUGAUGAGGCCGUUAGGCCGAA ACCCUUUC
11695





509
AAGGGUAUU GGUGACUG
2277
CAGUCACC CUGAUGAGGCCGUUAGGCCGAA AUACCCUU
11696





538
GUGACAGUA UCUUCUGC
2278
GCAGAAGA CUGAUGAGGCCGUUAGGCCGAA ACUGUCAC
11697





540
GACAGUAUC UUCUGCAA
2279
UUGCAGAA CUGAUGAGGCCGUUAGGCCGAA AUACUGUC
11698





542
CAGUAUCUU CUGCAAAA
2280
UUUUGCAG CUGAUGAGGCCGUUAGGCCGAA AGAUACUG
11699





543
AGUAUCUUC UGCAAAAC
2281
GUUUUGCA CUGAUGAGGCCGUUAGGCCGAA AAGAUACU
11700





555
AAAACACUC ACCAUUCC
2282
GGAAUGGU CUGAUGAGGCCGUUAGGCCGAA AGUGUUUU
11701





561
CUCACCAUU CCCAGGGU
2283
ACCCUGGG CUGAUGAGGCCGUUAGGCCGAA AUGGUGAG
11702





562
UCACCAUUC CCAGGGUG
2284
CACCCUGG CUGAUGAGGCCGUUAGGCCGAA AAUGGUGA
11703





573
AGGGUGGUU GGAAAUGA
2285
UCAUUUCC CUGAUGAGGCCGUUAGGCCGAA ACCACCCU
11704





583
GAAAUGAUA CUGGAGCC
2286
GGCUCCAG CUGAUGAGGCCGUUAGGCCGAA AUCAUUUC
11705





593
UGGAGCCUA CAAGUGCU
1546
AGCACUUG CUGAUGAGGCCGUUAGGCCGAA AGGCUCCA
10965





602
CAAGUGCUC GUACCGGG
2287
CCCGGUAC CUGAUGAGGCCGUUAGGCCGAA AGCACUUG
11706





605
GUGCUCGUA CCGGGACG
2288
CGUCCCGG CUGAUGAGGCCGUUAGGCCGAA ACGAGCAC
11707





615
CGGGACGUC GACAUAGC
2289
GCUAUGUC CUGAUGAGGCCGUUAGGCCGAA ACGUCCCG
11708





621
GUCGACAUA GCCUCCAC
2290
GUGGAGGC CUGAUGAGGCCGUUAGGCCGAA AUGUCGAC
11709





626
CAUAGCCUC CACUGUUU
2291
AAACAGUG CUGAUGAGGCCGUUAGGCCGAA AGGCUAUG
11710





633
UCCACUGUU UAUGUCUA
2292
UAGACAUA CUGAUGAGGCCGUUAGGCCGAA ACAGUGGA
11711





634
CCACUGUUU AUGUCUAU
2293
AUAGACAU CUGAUGAGGCCGUUAGGCCGAA AACAGUGG
11712





635
CACUGUUUA UGUCUAUG
2294
CAUAGACA CUGAUGAGGCCGUUAGGCCGAA AAACAGUG
11713





639
GUUUAUGUC UAUGUUCG
2295
CGAACAUA CUGAUGAGGCCGUUAGGCCGAA ACAUAAAC
11714





641
UUAUGUCUA UGUUCGAG
2296
CUCGAACA CUGAUGAGGCCGUUAGGCCGAA AGACAUAA
11715





645
GUCUAUGUU CGAGAUUA
2297
UAAUCUCG CUGAUGAGGCCGUUAGGCCGAA ACAUAGAC
11716





646
UCUAUGUUC GAGAUUAC
2298
GUAAUCUC CUGAUGAGGCCGUUAGGCCGAA AACAUAGA
11717





652
UUCGAGAUU ACAGAUCA
2299
UGAUCUGU CUGAUGAGGCCGUUAGGCCGAA AUCUCGAA
11718





653
UCGAGAUUA CAGAUCAC
2300
GUGAUCUG CUGAUGAGGCCGUUAGGCCGAA AAUCUCGA
11719





659
UUACAGAUC ACCAUUCA
2301
UGAAUGGU CUGAUGAGGCCGUUAGGCCGAA AUCUGUAA
11720





665
AUCACCAUU CAUCGCCU
2302
AGGCGAUG CUGAUGAGGCCGUUAGGCCGAA AUGGUGAU
11721





666
UCACCAUUC AUCGCCUC
2303
GAGGCGAU CUGAUGAGGCCGUUAGGCCGAA AAUGGUGA
11722





669
CCAUUCAUC GCCUCUGU
2304
ACAGAGGC CUGAUGAGGCCGUUAGGCCGAA AUGAAUGG
11723





674
CAUCGCCUC UGUCAGUG
2305
CACUGACA CUGAUGAGGCCGUUAGGCCGAA AGGCGAUG
11724





678
GCCUCUGUC AGUGACCA
2306
UGGUCACU CUGAUGAGGCCGUUAGGCCGAA ACAGAGGC
11725





696
CAUGGCAUC GUGUACAU
2307
AUGUACAC CUGAUGAGGCCGUUAGGCCGAA AUGCCAUG
11726





701
CAUCGUGUA CAUCACCG
2308
CGGUGAUG CUGAUGAGGCCGUUAGGCCGAA ACACGAUG
11727





705
GUGUACAUC ACCGAGAA
2309
UUCUCGGU CUGAUGAGGCCGUUAGGCCGAA AUGUACAC
11728





735
GUGGUGAUC CCCUGCCG
2310
CGGCAGGG CUGAUGAGGCCGUUAGGCCGAA AUCACCAC
11729





749
CCGAGGGUC GAUUUCAA
2311
UUGAAAUC CUGAUGAGGCCGUUAGGCCGAA ACCCUCGG
11730





753
GGGUCGAUU UCAAACCU
2312
AGGUUUGA CUGAUGAGGCCGUUAGGCCGAA AUCGACCC
11731





754
GGUCGAUUU CAAACCUC
2313
GAGGUUUG CUGAUGAGGCCGUUAGGCCGAA AAUCGACC
11732





755
GUCGAUUUC AAACCUCA
2314
UGAGGUUU CUGAUGAGGCCGUUAGGCCGAA AAAUCGAC
11733





762
UCAAACCUC AAUGUGUC
2315
GACACAUU CUGAUGAGGCCGUUAGGCCGAA AGGUUUGA
11734





770
CAAUGUGUC UCUUUGCG
2316
CGCAAAGA CUGAUGAGGCCGUUAGGCCGAA ACACAUUG
11735





772
AUGUGUCUC UUUGCGCU
2317
AGCGCAAA CUGAUGAGGCCGUUAGGCCGAA AGACACAU
11736





774
GUGUCUCUU UGCGCUAG
2318
CUAGCGCA CUGAUGAGGCCGUUAGGCCGAA AGAGACAC
11737





775
UGUCUCUUU GCGCUAGG
2319
CCUAGCGC CUGAUGAGGCCGUUAGGCCGAA AAGAGACA
11738





782
UUUGCGCUA GGUAUCCA
2320
UGGAUACC CUGAUGAGGCCGUUAGGCCGAA AGCGCAAA
11739





785
CGCUAGGUA UCCAGAAA
2321
UUUCUGGA CUGAUGAGGCCGUUAGGCCGAA ACCUAGCG
11740





787
CUAGGUAUC CAGAAAAG
2322
CUUUUCUG CUGAUGAGGCCGUUAGGCCGAA AWACCUAG
11741





800
AAAGAGAUU UGUUCCGG
2323
CCGGAACA CUGAUGAGGCCGUUAGGCCGAA AUCUCUUU
11742





801
AAGAGAUUU GUUCCGGA
2324
UCCGGAAC CUGAUGAGGCCGUUAGGCCGAA AAUCUCUU
11743





804
AGAUUUGUU CCGGAUGG
2325
CCAUCCGG CUGAUGAGGCCGUUAGGCCGAA ACAAAUCU
11744





805
GAUUUGUUC CGGAUGGA
2326
UCCAUCCG CUGAUGAGGCCGUUAGGCCGAA AACAAAUC
11745





822
AACAGAAUU UCCUGGGA
1595
UCCCAGGA CUGAUGAGGCCGUUAGGCCGAA AUUCUGUU
11014





823
ACAGAAUUU CCUGGGAC
1596
GUCCCAGG CUGAUGAGGCCGUUAGGCCGAA AAUUCUGU
11015





824
CAGAAUUUC CUOGGACA
1597
UGUCCCAG CUGAUGAGGCCGUUAGGCCGAA AAAUUCUG
11016





840
AGCGAGAUA GGCUUUAC
2327
GUAAAGCC CUGAUGAGGCCGUUAGGCCGAA AUCUCGCU
11746





845
GAUAGGCUU UACUCUCC
2328
GGAGAGUA CUGAUGAGGCCGUUAGGCCGAA AGCCUAUC
11747





846
AUAGGCUUU ACUCUCCC
2329
GGGAGAGU CUGAUGAGGCCGUUAGGCCGAA AAGCCUAU
11748





847
UAGGCUUUA CUCUCCCC
2330
GGGGAGAG CUGAUGAGGCCGUUAGGCCGAA AAAGCCUA
11749





850
GCUUUACUC UCCCCAGU
2331
ACUGGGGA CUGAUGAGGCCGUUAGGCCGAA AGUAAAGC
11750





852
UUUACUCUC CCCAGUUA
2332
UAACUGGG CUGAUGAGGCCGUUAGGCCGAA AGAGUAAA
11751





859
UCCCCAGUU ACAUGAUC
2333
GAUCAUGU CUGAUGAGGCCGUUAGGCCGAA ACUGGGGA
11752





860
CCCCAGUUA CAUGAUCA
2334
UGAUCAUG CUGAUGAGGCCGUUAGGCCGAA AACUGGGG
11753





867
UACAUGAUC AGCUAUGC
1605
GCAUAGCU CUGAUGAGGCCGUUAGGCCGAA AUCAUGUA
11024





872
GAUCAGCUA UGCCGGCA
2335
UGCCGGCA CUGAUGAGGCCGUUAGGCCGAA AGCUGAUC
11754





885
GGCAUGGUC UUCUGUGA
1607
UCACAGAA CUGAUGAGGCCGUUAGGCCGAA ACCAUGCC
11026





887
CAUGGUCUU CUGUGAGG
2336
CCUCACAG CUGAUGAGGCCGUUAGGCCGAA AGACCAUG
11755





888
AUGGUCUUC UGUGAGGC
2337
GCCUCACA CUGAUGAGGCCGUUAGGCCGAA AAGACCAU
11756





903
GCAAAGAUC AAUGAUGA
2338
UCAUCAUU CUGAUGAGGCCGUUAGGCCGAA AUCUUUGC
11757





917
UGAAACCUA UCAGUCUA
2339
UAGACUGA CUGAUGAGGCCGUUAGGCCGAA AGGUUUCA
11758





919
AAACCUAUC AGUCUAUC
2340
GAUAGACU CUGAUGAGGCCGUUAGGCCGAA AUAGGUUU
11759





923
CUAUCAGUC UAUCAUGU
2341
ACAUGAUA CUGAUGAGGCCGUUAGGCCGAA ACUGAUAG
11760





925
AUCAGUCUA UCAUGUAC
2342
GUACAUGA CUGAUGAGGCCGUUAGGCCGAA AGACUGAU
11761





927
CAGUCUAUC AUGUACAU
2343
AUGUACAU CUGAUGAGGCCGUUAGGCCGAA AUAGACUG
11035





932
UAUCAUGUA CAUAGUUG
2344
CAACUAUG CUGAUGAGGCCGUUAGGCCGAA ACAUGAUA
11762





936
AUGUACAUA GUUGUGGU
2345
ACCACAAC CUGAUGAGGCCGUUAGGCCGAA AUGUACAU
11763





939
UACAUAGUU GUGGUUGU
2346
ACAACCAC CUGAUGAGGCCGUUAGGCCGAA ACUAUGUA
11764





945
GUUGUGGUU GUAGGAUA
2347
UAUCCUAC CUGAUGAGGCCGUUAGGCCGAA ACCACAAC
11765





948
GUGGUUGUA GGAUAUAG
2348
CUAUAUCC CUGAUGAGGCCGUUAGGCCGAA ACAACCAC
11766





953
UGUAGGAUA UAGGAUUU
2349
AAAUCCUA CUGAUGAGGCCGUUAGGCCGAA AUCCUACA
11767





955
UAGGAUAUA GGAUUUAU
2350
AUAAAUCC CUGAUGAGGCCGUUAGGCCGAA AUAUCCUA
11768





960
UAUAGGAUU UAUGAUGU
1626
ACAUCAUA CUGAUGAGGCCGUUAGGCCGAA AUCCUAUA
11045





961
AUAGGAUUU AUGAUGUG
1627
CACAUCAU CUGAUGAGGCCGUUAGGCCGAA AAUCCUAU
11046





962
UAGGAUUUA UGAUGUGA
2351
UCACAUCA CUGAUGAGGCCGUUAGGCCGAA AAAUCCUA
11769





972
GAUGUGAUU CUGAGCCC
2352
GGGCUCAG CUGAUGAGGCCGUUAGGCCGAA AUCACAUC
11770





973
AUGUGAUUC UGAGCCCC
2353
GGGGCUCA CUGAUGAGGCCGUUAGGCCGAA AAUCACAU
11771





993
CAUGAAAUU GAGCUAUC
2354
GAUAGCUC CUGAUGAGGCCGUUAGGCCGAA AUUUCAUG
11772





999
AUUGAGCUA UCUGCCGG
2355
CCGGCAGA CUGAUGAGGCCGUUAGGCCGAA AGCUCAAU
11773





1001
UGAGCUAUC UGCCGGAG
2356
CUCCGGCA CUGAUGAGGCCGUUAGGCCGAA AUAGCUCA
11774





1017
GAAAAACUU GUCUUAAA
2357
UUUAAGAC CUGAUGAGGCCGUUAGGCCGAA AGUUUUUC
11775





1020
AAACUUGUC UUAAAUUG
2358
CAAUUUAA CUGAUGAGGCCGUUAGGCCGAA ACAAGUUU
11776





1022
ACUUGUCUU AAAUUGUA
2359
UACAAUUU CUGAUGAGGCCGUUAGGCCGAA AGACAAGU
11777





1023
CUUGUCUUA AAUUGUAC
1641
GUACAAUU CUGAUGAGGCCGUUAGGCCGAA AAGACAAG
11060





1027
UCUUAAAUU GUACAGCG
2360
OGOUGUAC CUGAUGAGGCCGUUAGGCCGAA AUUUAAGA
11778





1030
UAAAUUGUA CAGCGAGA
2361
UCUCGCUG CUGAUGAGGCCGUUAGGCCGAA ACAAUUUA
11779





1047
ACAGAGCUC AAUGUGGG
2362
CCCACAUU CUGAUGAGGCCGUUAGGCCGAA AGCUCUGU
11780





1059
GUGGGGCUU GAUCUCAC
2363
GUGAAAUC CUGAUGAGGCCGUUAGGCCGAA AGCCCCAC
11781





1063
GGCUUGAUU UCACCUGG
2364
CCAGGUGA CUGAUGAGGCCGUUAGGCCGAA AUCAAGCC
11782





1064
GCUUGAUUU CACCUGGC
2365
GCCAGGUG CUGAUGAGGCCGUUAGGCCGAA AAUCAAGC
11783





1065
CUUGAUUUC ACCUGGCA
2366
UGCCAGGU CUGAUGAGGCCGUUAGGCCGAA AAAUCAAG
11784





1076
CUGGCACUC UCCACCUU
2367
AAGGUGGA CUGAUGAGGCCGUUAGGCCGAA AGUGCCAG
11785





1078
GGCACUCUC CACCUUCA
2368
UGAAGGUG CUGAUGAGGCCGUUAGGCCGAA AGAGUGCC
11786





1084
CUCCACCUU CAAAGUCU
2369
AGACUUUG CUGAUGAGGCCGUUAGGCCGAA AGGUGGAG
11787





1085
UCCACCUUC AAAGUCUC
2370
GAGACUUU CUGAUGAGGCCGUUAGGCCGAA AAGGUGGA
11788





1091
UUCAAAGUC UCAUCAUA
2371
UAUGAUGA CUGAUGAGGCCGUUAGGCCGAA ACUUUGAA
11789





1093
CAAAGUCUC AUCAUAAG
2372
CUUAUGAU CUGAUGAGGCCGUUAGGCCGAA AGACUUUG
11790





1096
AGUCUCAUC AUAAGAAG
2373
CUUCUUAU CUGAUGAGGCCGUUAGGCCGAA AUGAGACU
11791





1099
CUCAUCAUA AGAAGAUU
2374
AAUCUUCU CUGAUGAGGCCGUUAGGCCGAA AUGAUGAG
11792





1107
AAGAAGAUU GUAAACCG
2375
CGGUUUAC CUGAUGAGGCCGUUAGGCCGAA AUCUUCUU
11793





1110
AAGAUUGUA AACCGGGA
2376
UCCCGGUU CUGAUGAGGCCGUUAGGCCGAA ACAAUCUU
11794





1130
GAAACCCUU UCCUGGGA
2377
UCCCAGGA CUGAUGAGGCCGUUAGGCCGAA AGGGUUUC
11795





1131
AAACCCUUU CCUGGGAC
2378
GUCCCAGG CUGAUGAGGCCGUUAGGCCGAA AAGGGUUU
11796





1132
AACCCUUUC CUGGGACU
2379
AGUCCCAG CUGAUGAGGCCGUUAGGCCGAA AAAGGGUU
11797





1154
GAAGAUGUU UUUGAGCA
2380
UGCUCAAA CUGAUGAGGCCGUUAGGCCGAA ACAUCUUC
11798





1155
AAGAUGUUU UUGAGCAC
2381
GUGCUCAA CUGAUGAGGCCGUUAGGCCGAA AACAUCUU
11799





1156
AGAUGUUUU UGAGCACC
2382
GGUGCUCA CUGAUGAGGCCGUUAGGCCGAA AAACAUCU
11800





1157
GAUGUUUUU GAGCACCU
2383
AGGUGCUC CUGAUGAGGCCGUUAGGCCGAA AAAACAUC
11801





1166
GAGCACCUU GACAAUAG
2384
CUAUUGUC CUGAUGAGGCCGUUAGGCCGAA AGGUGCUC
11802





1173
UUGACAAUA GAAAGUGU
2385
ACACUUUC CUGAUGAGGCCGUUAGGCCGAA AUUGUCAA
11803





1205
AGGGGAAUA CACCUGUG
2386
CACAGGUG CUGAUGAGGCCGUUAGGCCGAA AUUCCCCU
11804





1215
ACCUGUGUA GCGUCCAG
2387
CUGGACGC CUGAUGAGGCCGUUAGGCCGAA ACACAGGU
11805





1220
UGUAGCGUC CAGUGGAC
2388
GUCCACUG CUGAUGAGGCCGUUAGGCCGAA ACGCUACA
11806





1236
CGGAUGAUC AAGAGAAA
2389
UUUCUCUU CUGAUGAGGCCGUUAGGCCGAA AUCAUCCG
11807





1246
AGAGAAAUA GAACAUUU
2390
AAAUGUUC CUGAUGAGGCCGUUAGGCCGAA AUUUCUCU
11808





1253
UAGAACAUU UGUCCGAG
2391
CUCGGACA CUGAUGAGGCCGUUAGGCCGAA AUGUUCUA
11809





1254
AGAACAUUU GUCCGAGU
2392
ACUCGGAC CUGAUGAGGCCGUUAGGCCGAA AAUGUUCU
11810





1257
ACAUUUGUC CGAGUUCA
2393
UGAACUCG CUGAUGAGGCCGUUAGGCCGAA ACAAAUGU
11811





1263
GUCCGAGUU CACACAAA
2394
UUUGUGUG CUGAUGAGGCCGUUAGGCCGAA ACUCGGAC
11812





1264
UCCGAGUUC ACACAAAG
2395
CUUUGUGU CUGAUGAGGCCGUUAGGCCGAA AACUCGGA
11813





1276
CAAAGCCUU UUAUUGCU
2396
AGCAAUAA CUGAUGAGGCCGUUAGGCCGAA AGGCUUUG
11814





1277
AAAGCCUUU UAUUGCUU
2397
AAGCAAUA CUGAUGAGGCCGUUAGGCCGAA AAGGCUUU
11815





1278
AAGCCUUUU AUUGCUUU
2398
AAAGCAAU CUGAUGAGGCCGUUAGGCCGAA AAAGGCUU
11816





1279
AGCCUUUUA UUGCUUUC
2399
GAAAGCAA CUGAUGAGGCCGUUAGGCCGAA AAAAGGCU
11817





1281
CCUUUUAUU GCUUUCGG
2400
CCGAAAGC CUGAUGAGGCCGUUAGGCCGAA AUAAAAGG
11818





1285
UUAUUGCUU UCGGUAGU
2401
ACUACCGA CUGAUGAGGCCGUUAGGCCGAA AGCAAUAA
11819





1286
UAUUGCUUU CGGUAGUG
2402
CACUACCG CUGAUGAGGCCGUUAGGCCGAA AAGCAAUA
11820





1287
AUUGCUUUC GGUAGUGG
2403
CCACUACC CUGAUGAGGCCGUUAGGCCGAA AAAGCAAU
11821





1291
CUUUCGGUA GUGGGAUG
2404
CAUCCCAC CUGAUGAGGCCGUUAGGCCGAA ACCGAAAG
11822





1304
GAUGAAAUC UUUGGUGG
2405
CCACCAAA CUGAUGAGGCCGUUAGGCCGAA AUUUCAUC
11823





1306
UGAAAUCUU UGGUGGAA
2406
UUCCACCA CUGAUGAGGCCGUUAGGCCGAA AGAUUUCA
11824





1307
GAAAUCUUU GGUGGAAG
2407
CUUCCACC CUGAUGAGGCCGUUAGGCCGAA AAGAUUUC
11825





1330
UGGGCAGUC AAGUCCGA
2408
UCGGACUU CUGAUGAGGCCGUUAGGCCGAA ACUGCCCA
11826





1335
AGUCAAGUC CGAAUCCC
2409
GGGAUUCG CUGAUGAGGCCGUUAGGCCGAA ACUUGACU
11827





1341
GUCCGAAUC CCUGUGAA
2410
UUCACAGG CUGAUGAGGCCGUUAGGCCGAA AUUCGGAC
11828





1352
UGUGAAGUA UCUCAGUU
2411
AACUGAGA CUGAUGAGGCCGUUAGGCCGAA ACUUCACA
11829





1354
UGAAGUAUC UCAGUUAC
2412
GUAACUGA CUGAUGAGGCCGUUAGGCCGAA AUACUUCA
11830





1356
AAGUAUCUC AGUUACCC
2413
GGGUAACU CUGAUGAGGCCGUUAGGCCGAA AGAUACUU
11831





1360
AUCUCAGUU ACCCAGCU
2414
AGCUGGGU CUGAUGAGGCCGUUAGGCCGAA ACUGAGAU
11832





1361
UCUCAGUUA CCCAGCUC
2415
GAGCUGGG CUGAUGAGGCCGUUAGGCCGAA AACUGAGA
11833





1369
ACCCAGCUC CUGAUAUC
2416
GAUAUCAG CUGAUGAGGCCGUUAGGCCGAA AGCUGGGU
11834





1375
CUCCUGAUA UCAAAUGG
2417
CCAUUUGA CUGAUGAGGCCGUUAGGCCGAA AUCAGGAG
11835





1377
CCUGAUAUC AAAUGGUA
2418
UACCAUUU CUGAUGAGGCCGUUAGGCCGAA AUAUCAGG
11836





1385
CAAAUGGUA CAGAAAUG
2419
CAUUUCUG CUGAUGAGGCCGUUAGGCCGAA ACCAUUUG
11837





1404
AGGCCCAUU GAGUCCAA
2420
UUGGACUC CUGAUGAGGCCGUUAGGCCGAA AUGGGCCU
11838





1409
CAUUGAGUC CAACUACA
2421
UGUAGGUG CUGAUGAGGCCGUUAGGCCGAA ACUCAAUG
11839





1415
GUCCAACUA CACAAUGA
2422
UCAUUGUG CUGAUGAGGCCGUUAGGCCGAA AGUUGGAC
11840





1425
ACAAUGAUU GUUGGCGA
2423
UCGCCAAC CUGAUGAGGCCGUUAGGCCGAA AUCAUUGU
11841





1428
AUGAUUGUU GGCGAUGA
2424
UCAUCGCC CUGAUGAGGCCGUUAGGCCGAA ACAAUCAU
11842





1440
GAUGAACUC ACCAUCAU
2425
AUGAUGGU CUGAUGAGGCCGUUAGGCCGAA AGUUCAUC
11843





1446
CUCACCAUC AUGGAAGU
2426
ACUUCCAU CUGAUGAGGCCGUUAGGCCGAA AUGGUGAG
11844





1478
AGGAAACUA CACGGUCA
2427
UGACCGUG CUGAUGAGGCCGUUAGGCCGAA AGUUUCCU
11845





1485
UACACGGUC AUCCUCAC
2428
GUGAGGAU CUGAUGAGGCCGUUAGGCCGAA ACCGUGUA
11846





1488
ACGGUCAUC CUCACCAA
2429
UUGGUGAG CUGAUGAGGCCGUUAGGCCGAA AUGACCGU
11847





1491
GUCAUCCUC ACCAACCC
2430
GGGUUGGU CUGAUGAGGCCGUUAGGCCGAA AGGAUGAC
11848





1503
AACCCCAUU UCAAUGGA
2431
UCCAUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGGGUU
11849





1504
ACCCCAUUU CAAUGGAG
2432
CUCCAUUG CUGAUGAGGCCGUUAGGCCGAA AAUGGGGU
11850





1505
CCCCAUUUC AAUGGAGA
2433
UCUCCAUU CUGAUGAGGCCGUUAGGCCGAA AAAUGGGG
11851





1530
CACAUGGUC UCUCUGGU
2434
ACCAGAGA CUGAUGAGGCCGUUAGGCCGAA ACCAUGUG
11852





1532
CAUGGUCUC UCUGGUUG
2435
CAACCAGA CUGAUGAGGCCGUUAGGCCGAA AGACCAUG
11853





1534
UGGUCUCUC UGGUUGUG
1714
CACAACCA CUGAUGAGGCCGUUAGGCCGAA AGAGACCA
11133





1539
UCUCUGGUU GUGAAUGU
2436
ACAUUCAC CUGAUGAGGCCGUUAGGCCGAA ACCAGAGA
11854





1548
GUGAAUGUC CCACCCCA
2437
UGGGGUGG CUGAUGAGGCCGUUAGGCCGAA ACAUUCAC
11855





1560
CCCCAGAUC GGUGAGAA
2438
UUCUCACC CUGAUGAGGCCGUUAGGCCGAA AUCUGGGG
11137





1574
GAAAGCCUU GAUCUCGC
2439
GCGAGAUC CUGAUGAGGCCGUUAGGCCGAA AGGCUUUC
11856





1578
GCCUUGAUC UCGCCUAU
2440
AUAGGCGA CUGAUGAGGCCGUUAGGCCGAA AUCAAGGC
11857





1580
CUUGAUCUC GCCUAUGG
2441
CCAUAGGC CUGAUGAGGCCGUUAGGCCGAA AGAUCAAG
11858





1585
UCUCGCCUA UGGAUUCC
2442
GGAAUCCA CUGAUGAGGCCGUUAGGCCGAA AGGCGAGA
11859





1591
CUAUGGAUU CCUACCAG
2443
CUGGUAGG CUGAUGAGGCCGUUAGGCCGAA AUCCAUAG
11860





1592
UAUGGAUUC CUACCAGU
2444
ACUGGUAG CUGAUGAGGCCGUUAGGCCGAA AAUCCAUA
11861





1595
GGAUUCCUA CCAGUAUG
2445
CAUACUGG CUGAUGAGGCCGUUAGGCCGAA AGGAAUCC
11862





1601
CUACCAGUA UGGOACCA
2446
UGGUCCCA CUGAUGAGGCCGUUAGGCCGAA ACUGGUAG
11863





1619
GCAGACAUU GACAUGCA
2447
UGCAUGUC CUGAUGAGGCCGUUAGGCCGAA AUGUCUGC
11864





1632
UCCACAGUC UACGCCAA
2448
UUGGCGUA CUGAUGAGGCCGUUAGGCCGAA ACUGUGCA
11865





1634
CACAGUCUA CGCCAACC
2449
GGUUGGCG CUGAUGAGGCCGUUAGGCCGAA AGACUGUG
11866





1645
CCAACCCUC CCCUGCAC
2450
GUGCAGGG CUGAUGAGGCCGUUAGGCCGAA AGGGUUGG
11867





1659
CACCACAUC CAGUGGUA
2451
UACCACUG CUGAUGAGGCCGUUAGGCCGAA AUGUGGUG
11868





1667
CCAGUGGUA CUGGCAGC
2452
GCUGCCAG CUGAUGAGGCCGUUAGGCCGAA ACCACUGG
11869





1677
UGGCAGCUA GAAGAAGC
2453
GCUUCUUC CUGAUGAGGCCGUUAGGCCGAA AGCUGCCA
11870





1691
AGCCUGCUC CUACAGAC
2454
GUCUGUAG CUGAUGAGGCCGUUAGGCCGAA AGCAGGCU
11871





1694
CUGCUCCUA CAGACCCG
2455
CGGGUCUG CUGAUGAGGCCGUUAGGCCGAA AGGAGCAG
11872





1718
AAGCCCGUA UGCUUGUA
2456
UACAAGCA CUGAUGAGGCCGUUAGGCCGAA ACGGGCUU
11873





1723
CGUAUGCUU GUAAAGAA
2457
UUCUUUAC CUGAUGAGGCCGUUAGGCCGAA AGCAUACG
11874





1726
AUGCUUGUA AAGAAUGG
2458
CCAUUCUU CUGAUGAGGCCGUUAGGCCGAA ACAAGCAU
11875





1750
UGGAGGAUU UCCAGGGG
2459
CCCCUGGA CUGAUGAGGCCGUUAGGCCGAA AUCCUCCA
11876





1751
GGAGGAUUU CCAGGGGG
2460
CCCCCUGG CUGAUGAGGCCGUUAGGCCGAA AAUCCUCC
11877





1752
GAGGAUUUC CAGGGGGG
2461
CCCCCCUG CUGAUGAGGCCGUUAGGCCGAA AAAUCCUC
11878





1770
AACAAGAUC GAAGUCAC
2462
GUGACUUC CUGAUGAGGCCGUUAGGCCGAA AUCUUGUU
11879





1776
AUCGAAGUC ACCAAAAA
2463
UUUUUGGU CUGAUGAGGCCGUUAGGCCGAA ACUUCGAU
11880





1790
AAACCAAUA UGCCCUGA
2464
UCAGGGCA CUGAUGAGGCCGUUAGGCCGAA AUUGGUUU
11881





1800
GCCCUGAUU GAAGGAAA
2465
UUUCCUUC CUGAUGAGGCCGUUAGGCCGAA AUCAGGGC
11882





1821
AAAACUGUA AGUACGCU
2466
AGCGUACU CUGAUGAGGCCGUUAGGCCGAA ACAGUUUU
11883





1825
CUGUAAGUA CGCUGGUC
2467
GACCAGCG CUGAUGAGGCCGUUAGGCCGAA ACUUACAG
11884





1833
ACGCUGGUC AUCCAAGC
2468
GCUUGGAU CUGAUGAGGCCGUUAGGCCGAA ACCAGCGU
11885





1836
CUGGUCAUC CAAGCUGC
2469
GCAGCUUG CUGAUGAGGCCGUUAGGCCGAA AUGACCAG
11886





1853
CAACGUGUC AGCGUUGU
2470
ACAACGCU CUGAUGAGGCCGUUAGGCCGAA ACACGUUG
11887





1859
GUCAGCGUU GUACAAAU
2471
AUUUGUAC CUGAUGAGGCCGUUAGGCCGAA ACGCUGAC
11888





1862
AGCGUUGUA CAAAUGUG
2472
CACAUUTU CUGAUGAGGCCGUUAGGCCGAA ACAACGCU
11889





1878
GAAGCCAUC AACAAAGC
2473
GCUUUGUU CUGAUGAGGCCGUUAGGCCGAA AUGGCUUC
11890





1905
GAGAGGGUC AUCUCCUU
2474
AAGGAGAU CUGAUGAGGCCGUUAGGCCGAA ACCCUCUC
11891





1908
AGGGUCAUC UCCUUCCA
2475
UGGAAGGA CUGAUGAGGCCGUUAGGCCGAA AUGACCCU
11892





1910
GOUCAUCUC CUUCCAUG
2476
CAUGGAAG CUGAUGAGGCCGUUAGGCCGAA AGAUGACC
11893





1913
CAUCUCCUU CCAUGUGA
2477
UCACAUGG CUGAUGAGGCCGUUAGGCCGAA AGGAGAUG
11894





1914
AUCUCCUUC CAUGUGAU
2478
AUCACAUG CUGAUGAGGCCGUUAGGCCGAA AAGGAGAU
11895





1923
CAUGUGAUC AGGGGUCC
2479
GGACCCCU CUGAUGAGGCCGUUAGGCCGAA AUCACAUG
11896





1930
UCAGGGGUC CUGAAAUU
2480
AAUUUCAG CUGAUGAGGCCGUUAGGCCGAA ACCCCUGA
11897





1938
CCUGAAAUU ACUGUGCA
2481
UGCACAGU CUGAUGAGGCCGUUAGGCCGAA AUUUCAGG
11898





1939
CUGAAAUUA CUGUGCAA
2482
UUGCACAG CUGAUGAGGCCGUUAGGCCGAA AAUUUCAG
11899





1982
GAGUGUGUC CCUGUUGU
2483
ACAACAGG CUGAUGAGGCCGUUAGGCCGAA ACACACUC
11900





1988
GUCCCUGUU GUGCACUG
2484
CAGUGCAC CUGAUGAGGCCGUUAGGCCGAA ACAGGGAC
11901





2008
ACAGAAAUA CGUUUGAG
2485
CUCAAACG CUGAUGAGGCCGUUAGGCCGAA AUUUCUGU
11902





2012
AAAUACGUU UGAGAACC
2486
GGUUCUCA CUGAUGAGGCCGUUAGGCCGAA ACGUAUUU
11903


2013
AAUACGUUU GAGAACCU
2487
AGGUUCUC CUGAUGAGGCCGUUAGGCCGAA AACGUAUU
11904





2022
GAGAACCUC ACGUGGUA
2488
UACCACGU CUGAUGAGGCCGUUAGGCCGAA AGGUUCUC
11905





2030
CACGUGGUA CAAGCUUG
2489
CAAGCUUG CUGAUGAGGCCGUUAGGCCGAA ACCACGUG
11906





2037
UACAAGCUU GGCUCACA
2490
UGUGAGCC CUGAUGAGGCCGUUAGGCCGAA AGCUUGUA
11907





2042
GCUUGGCUC ACAGGCAA
2491
UUGCCUGU CUGAUGAGGCCGUUAGGCCGAA AGCCAAGC
11908





2054
GGCAACAUC GGUCCACA
2492
UGUGGACC CUGAUGAGGCCGUUAGGCCGAA AUGUUGCC
11909





2058
ACAUCGGUC CACAUGGG
2493
CCCAUGUG CUGAUGAGGCCGUUAGGCCGAA ACCGAUGU
11910





2072
GGGCGAAUC ACUCACAC
2494
GUGUGAGU CUGAUGAGGCCGUUAGGCCGAA AUUCGCCC
11911





2076
GAAUCACUC ACACCAGU
2495
ACUGGUGU CUGAUGAGGCCGUUAGGCCGAA AGUGAUUC
11912





2085
ACACCAGUU UGCAAGAA
2496
UUCUUGCA CUGAUGAGGCCGUUAGGCCGAA ACUGGUGU
11913





2086
CACCAGUUU GCAAGAAC
2497
GUUCUUGC CUGAUGAGGCCGUUAGGCCGAA AACUGGUG
11914





2096
CAAGAACUU GGAUGCUC
2498
GAGCAUCC CUGAUGAGGCCGUUAGGCCGAA AGUUCUUG
11915





2104
UGGAUGCUC UUUGGAAA
2499
UUUCCAAA CUGAUGAGGCCGUUAGGCCGAA AGCAUCCA
11916





2106
GAUGCUCUU UGGAAACU
2500
AGUUUCCA CUGAUGAGGCCGUUAGGCCGAA AGACCAUC
11917





2107
AUGCUCUUU GGAAACUG
2501
CAGUUUCC CUGAUGAGGCCGUUAGGCCGAA AAGAGCAU
11918





2129
CACCAUGUU UUCUAACA
2502
UGUUAGAA CUGAUGAGGCCGUUAGGCCGAA ACAUGGUG
11919





2130
ACCAUGUUU UCUAACAG
2503
CUGUUAGA CUGAUGAGGCCGUUAGGCCGAA AACAUGGU
11920





2131
CCAUGUUUU CUAACAGC
2504
GCUGUUAG CUGAUGAGGCCGUUAGGCCGAA AAACAUGG
11921





2132
CAUGUUUUC UAACAGCA
2505
UGCUGUUA CUGAUGAGGCCGUUAGGCCGAA AAAACAUG
11922





2134
UGUUUUCUA ACACCACA
2506
UGUGCUGU CUGAUGAGGCCGUUAGGCCGAA AGAAAACA
11923





2151
AAUGACAUC UUGAUUGU
2507
ACAAUCAA CUGAUGAGGCCGUUAGGCCGAA AUGUCAUU
11924





2153
UGACAUCUU GAUUGUGG
2508
CCACAAUC CUGAUGAGGCCGUUAGGCCGAA AGAUGUCA
11925





2157
AUCUUGAUU GUGGCAUU
2509
AAUGCCAC CUGAUGAGGCCGUUAGGCCGAA AUCAAGAU
11926





2165
UGUGGCAUU UCAGAAUG
2510
CAUUCUGA CUGAUGAGGCCGUUAGGCCGAA AUGCCACA
11927





2166
GUGGCAUUU CAGAAUGC
2511
GCAUUCUG CUGAUGAGGCCGUUAGGCCGAA AAUGCCAC
11928





2167
UGGCAUUUC AGAAUGCC
2512
GGCAUUCU CUGAUGAGGCCGUUAGGCCGAA AAAUGCCA
11929





2177
GAAUGCCUC UCUGCAGG
2513
CCUGCAGA CUGAUGAGGCCGUUAGGCCGAA AGGCAUUC
11930





2179
AUGCCUCUC UGCAGGAC
2514
GUCCUGCA CUGAUGAGGCCGUUAGGCCGAA AGAGGCAU
11921





2198
AGGCGACUA UGUUUGCU
2515
AGCAAACA CUGAUGAGGCCGUUAGGCCGAA AGUCGCCU
11932





2202
GACUAUGUU UGCUCUGC
2516
GCAGAGCA CUGAUGAGGCCGUUAGGCCGAA ACAUAGUC
11933





2203
ACUAUGUUU GCUCUGCU
2517
AGCAGAGC CUGAUGAGGCCGUUAGGCCGAA AACAUAGU
11934





2207
UGUUUGCUC UGCUCAAG
2518
CUUGAGCA CUGAUGAGGCCGUUAGGCCGAA AGCAAACA
11935





2212
GCUCUGCUC AAGAUAAG
2519
CUUAUCUU CUGAUGAGGCCGUUAGGCCGAA AGCAGAGC
11936





2218
CUCAAGAUA AGAAGACC
2520
GGUCUUCU CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
11937





2239
AAAGACAUU GCCUGGUC
2521
GACCAGGC CUGAUGAGGCCGUUAGGCCGAA AUGUCUUU
11938





2247
UGCCUGGUC AAACAGCU
2522
AGCUGUUU CUGAUGAGGCCGUUAGGCCGAA ACCAGGCA
11939





2256
AAACAGCUC AUCAUCCU
2523
AGGAUGAU CUGAUGAGGCCGUUAGGCCGAA AGCUGUUU
11940





2259
CAGCUCAUC AUCCUAGA
2524
UCUAGGAU CUGAUGAGGCCGUUAGGCCGAA AUGAGCUG
11941





2262
CUCAUCAUC CUAGAGCG
2525
CGCUCUAG CUGAUGAGGCCGUUAGGCCGAA AUGAUGAG
11942





2265
AUCAUCCUA GAGCGCAU
2526
AUGCGCUC CUGAUGAGGCCGUUAGGCCGAA AGGAUGAU
11943





2286
CCCAUGAUC ACCGGAAA
2527
UUUCCGGU CUGAUGAGGCCGUUAGGCCGAA AUCAUGGG
11944





2296
CCGGAAAUC UGGAGAAU
2528
AUUCUCCA CUGAUGAGGCCGUUAGGCCGAA AUUUCCGG
11945





2305
UGGAGAAUC AGACAACA
2529
UGUUGUCU CUGAUGAGGCCGUUAGGCCGAA AUUCUCCA
11946





2319
ACAACCAUU GGCGAGAC
2530
GUCUCGCC CUGAUGAGGCCGUUAGGCCGAA AUGGUUGU
11947





2331
GAGACCAUU GAAGUGAC
2531
GUCACUUC CUGAUGAGGCCGUUAGGCCGAA AUGGUCUC
11948





2341
AAGUGACUU GCCCAGCA
2532
UGCUGGGC CUGAUGAGGCCGUUAGGCCGAA AGUCACUC
11949





2351
CCCAGCAUC UGGAAAUC
2533
GAUUUCCA CUGAUGAGGCCGUUAGGCCGAA AUGCUGGG
11950





2359
CUGGAAAUC CUACCCCA
2534
UGGGGUAG CUGAUGAGGCCGUUAGGCCGAA AUUUCCAG
11951





2362
GAAAUCCUA CCCCACAC
2535
GUGUGGGG CUGAUGAGGCCGUUAGGCCGAA AGGAUUUC
11952





2373
CCACACAUU ACAUGGUU
2536
AACCAUGU CUGAUGAGGCCGUUAGGCCGAA AUGUGUGG
11953





2374
CACACAUUA CAUGGUUC
2537
GAACCAUG CUGAUGAGGCCGUUAGGCCGAA AAUGUGUG
11954





2381
UACAUGGUU CAAAGACA
2538
UGUCUUUG CUGAUGAGGCCGUUAGGCCGAA ACCAUGUA
11955





2382
ACAUGGUUC AAAGACAA
2539
UUGUCUUU CUGAUGAGGCCGUUAGGCCGAA AACCAUGU
11956





2403
ACCCUGGUA GAAGAUUC
2540
GAAUCUUC CUGAUGAGGCCGUUAGGCCGAA ACCAGGGU
11957





2410
UAGAAGAUU CAGGCAUU
2541
AAUGCCUG CUGAUGAGGCCGUUAGGCCGAA AUCUUCUA
11958





2411
AGAAGAUUC AGGCAUUG
2542
CAAUGCCU CUGAUGAGGCCGUUAGGCCGAA AAUCUUCU
11959





2418
UCAGGCAUU GUACUGAG
2543
CUCAGUAC CUGAUGAGGCCGUUAGGCCGAA AUGCCUGA
11960





2421
GGCAUUGUA CUGAGAGA
2544
UCUCUCAG CUGAUGAGGCCGUUAGGCCGAA ACAAUGCC
11961





2449
ACCUGACUA UCCGCAGG
2545
CCUGCGGA CUGAUGAGGCCGUUAGGCCGAA AGUCAGGU
11962





2451
CUGACUAUC CGCAGGGU
2546
ACCCUGCG CUGAUGAGGCCGUUAGGCCGAA AUAGUCAG
11963





2481
GGAGGCCUC UACACCUG
2547
CAGGUGUA CUGAUGAGGCCGUUAGGCCGAA AGGCCUCC
11964





2483
AGGCCUCUA CACCUGCC
1847
GGCAGGUG CUGAUGAGGCCGUUAGGCCGAA AGAGGCCU
11266





2505
UGCAAUGUC CUUGGCUG
2548
CAGCCAAG CUGAUGAGGCCGUUAGGCCGAA ACAUUGCA
11965





2508
AAUGUCCUU GGCUGUGC
2549
GCACAGCC CUGAUGAGGCCGUUAGGCCGAA AGGACAUU
11966





2532
GAGACGCUC UUCAUAAU
2550
AUUAUGAA CUGAUGAGGCCGUUAGGCCGAA AGCGUCUC
11967





2534
GACGCUCUU CAUAAUAG
2551
CUAUUAUG CUGAUGAGGCCGUUAGGCCGAA AGAGCGUC
11968





2535
ACGCUCUUC AUAAUAGA
2552
UCUAUUAU CUGAUGAGGCCGUUAGGCCGAA AAGAGCGU
11969





2538
CUCUUCAUA AUAGAAGG
2553
CCUUCUAU CUGAUGAGGCCGUUAGGCCGAA AUGAAGAG
11970





2541
UUCAUAAUA GAAGGUGC
1857
GCACCUUC CUGAUGAGGCCGUUAGGCCGAA AUUAUGAA
11276





2567
GACCAACUU GGAAGUCA
2554
UGACUUCC CUGAUGAGGCCGUUAGGCCGAA AGUUGGUC
11971





2574
UUGGAAGUC AUUAUCCU
2555
AGGAUAAU CUGAUGAGGCCGUUAGGCCGAA ACUCCCAA
11972





2577
GAAGUCAUU AUCCUCGU
2556
ACGAGGAU CUGAUGAGGCCGUUAGGCCGAA AUGACCUC
11973





2578
AAGUCAUUA UCCUCGUC
2557
GACGAGGA CUGAUGAGGCCGUUAGGCCGAA AAUGACUU
11974





2580
GUCAUUAUC CUCGUCGG
2558
CCGACGAG CUGAUGAGGCCGUUAGGCCGAA AUAAUGAC
11975





2583
AUUAUCCUC GUCGGCAC
2559
GUGCCGAC CUGAUGAGGCCGUUAGGCCGAA AGGAUAAU
11976





2586
AUCCUCGUC GGCACUGC
2560
GCAGUGCC CUGAUGAGGCCGUCAGGCCGAA ACGAGGAU
11977





2601
GCAGUGAUU GCCAUGUU
2561
AACAUGGC CUGAUGAGGCCGUUAGGCCGAA AUCACUGC
11978





2609
UGCCAUGUU CUUCUGGC
1867
GCCAGAAG CUGAUGAGGCCGUUAGGCCGAA ACAUGGCA
11286





2610
GCCAUGUUC UUCUGGCU
1868
AGCCAGAA CUGAUGAGGCCGUUAGGCCGAA AACAUGGC
11287





2612
CAUGUUCUU CUCGCUCC
2562
GGAGCCAG CUGAUGAGGCCGUUAGGCCGAA AGAACAUG
11979





2613
AUGUUCUUC UGGCUCCU
2563
AGGAGCCA CUGAUGAGGCCGUUAGGCCGAA AAGAACAU
11980





2619
UUCUGGCUC CUUCUUGU
2564
ACAAGAAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGAA
11290





2622
UGGCUCCUU CUUGUCAU
2565
AUGACAAG CUGAUGAGGCCGUUAGGCCGAA AGGAGCCA
11981





2623
GGCUCCUUC UUGUCAUU
2566
AAUGACAA CUGAUGAGGCCGUUAGGCCGAA AAGGAGCC
11982





2625
CUCCUUCUU GUCAUUGU
2567
ACAAUGAC CUGAUGAGGCCGUUAGGCCGAA AGAAGGAG
11983





2628
CUUCUUGUC AUUGUCCU
2568
AGGACAAU CUGAUGAGGCCGUUAGGCCGAA ACAAGAAG
11984





2631
CUUGUCAUU GUCCUACG
2569
OGUAGGAC CUGAUGAGGCCGUUAGGCCGAA AUGACAAG
11985





2634
GUCAUUGUC CUACOGAC
2570
GUCCGUAG CUGAUGAGGCCGUUAGGCCGAA ACAAUGAC
11986





2637
AUUGUCCUA CGGACCGU
2571
ACGGUCCG CUGAUGAGGCCGUUAGGCCGAA AGGACAAU
11987





2646
CGGACCGUU AAGCGGGC
2572
GCCCGCUU CUGAUGAGGCCGUUAGGCCGAA ACGGUCCG
11988





2647
GGACCGUUA AGCGGGCC
1880
GGCCCGCU CUGAUGAGGCCGUUAGGCCGAA AACGGUCC
11299





2681
GACAGGCUA CUUGUCUA
2573
UAGACAAG CUGAUGAGGCCGUUAGGCCGAA AGCCUGUC
11989





2684
AGGCUACUU GUCUAUUG
2574
CAAUAGAC CUGAUGAGGCCGUUAGGCCGAA AGUAGCCU
11990





2687
CUACUUGUC UAUUGUCA
2575
UGACAAUA CUGAUGAGGCCGUUAGGCCGAA ACAAGUAG
11991





2689
ACUUGUCUA UUGUCAUG
2576
CAUGACAA CUGAUGAGGCCGUUAGGCCGAA AGACAAGU
11992





2691
UUGUCUAUU GUCAUGGA
2577
UCCAUGAC CUGAUGAGGCCGUUAGGCCGAA AUAGACAA
11993





2694
UCUAUUGUC AUGGAUCC
2578
GGAUCCAU CUGAUGAGGCCGUUAGGCCGAA ACAAUAGA
11994





2701
UCAUGGAUC CAGAUGAA
1886
UUCAUCUG CUGAUGAGGCCGUUAGGCCGAA AUCCAUGA
11305





2711
AGAUGAAUU GCCCUUGG
2579
CCAAGGGC CUGAUGAGGCCGUUAGGCCGAA AUUCAUCU
11995





2717
AUUGCCCUU GGAUGAGC
2580
GCUCAUCC CUGAUGAGGCCGUUAGGCCGAA AGGGCAAU
11996





2738
UGAACGCUU GCCUUAUG
2581
CAUAAGGC CUGAUGAGGCCGUUAGGCCGAA AGCGUUCA
11997





2743
GCUUGCCUU AUGAUGCC
2582
GGCAUCAU CUGAUGAGGCCGUUAGGCCGAA AGGCAAGC
11998





2744
CUUGCCUUA UGAUGCCA
2583
UGGCAUCA CUGAUGAGGCCGUUAGGCCGAA AAGGCAAG
11999





2765
GUGGGAAUU CCCCAGGG
2584
CCCUGGGG CUGAUGAGGCCGUUAGGCCGAA AUUCCCAC
12000





2766
UGGGAAUUC CCCAGGGA
2585
UCCCUGGG CUGAUGAGGCCGUUAGGCCGAA AAUUCCCA
12001





2787
CUGAAACUA GGAAAACC
2586
GGUUUUCC CUGAUGAGGCCGUUAGGCCGAA AGUUUCAG
12002





2797
GAAAACCUC UUGGCCGC
2587
GCGGCCAA CUGAUGAGGCCGUUAGGCCGAA AGGUUUUC
12003





2799
AAACCUCUU GGCCGCGG
2588
CCGCGGCC CUGAUGAGGCCGUUAGGCCGAA AGAGGUUU
12004





2813
CGGUGCCUU CGGCCAAG
2589
CUUGGCCG CUGAUGAGGCCGUUAGGCCGAA AGGCACCG
12005





2814
GGUGCCUUC GGCCAAGU
2590
ACUUGGCC CUGAUGAGGCCGUUAGGCCGAA AAGGCACC
12006





2826
CAAGUGAUU GAGGCAGA
2591
UCUGCCUC CUGAUGAGGCCGUUAGGCCGAA AUCACUUG
12007





2839
CAGACGCUU UUGGAAUU
2592
AAUUCCAA CUGAUGAGGCCGUUAGGCCGAA AGCGUCUG
12008





2840
AGACGCUUU UGGAAUUG
2593
CAAUUCCA CUGAUGAGGCCGUUAGGCCGAA AAGCGUCU
12009





2841
GACGCUUUU GGAAUUGA
2594
UCAAUUCC CUGAUGAGGCCGUUAGGCCGAA AAAGCGUC
12010





2847
UUUGGAAUU GACAAGAC
1903
GUCUUGUC CUGAUGAGGCCGUUAGGCCGAA AUUCCAAA
11322





2863
CAGCGACUU GCAAAACA
2595
UGUUUUGC CUGAUGAGGCCGUUAGGCCGAA AGUCGCUG
12011





2874
AAAACAGUA GCCGUCAA
2596
UUGACGGC CUGAUGAGGCCGUUAGGCCGAA ACUGUUUU
12012





2880
GUAGCCGUC AAGAUGUU
2597
AACAUCUU CUGAUGAGGCCGUUAGGCCGAA ACGGCUAC
12013





2888
CAAGAUGUU GAAAGAAG
2598
CUUCUUUC CUGAUGAGGCCGUUAGGCCGAA ACAUCUUG
12014





2917
GCGAGCAUC GAGCCCUC
2599
GAGGGCUC CUGAUGAGGCCGUUAGGCCGAA AUGCUCGC
12015





2925
CGAGCCCUC AUGUCUGA
2600
UCAGACAU CUGAUGAGGCCGUUAGGCCGAA AGGGCUCG
12016





2930
CCUCAUGUC UGAACUCA
2601
UGAGUUCA CUGAUGAGGCCGUUAGGCCGAA ACAUGAGG
12017





2937
UCUGAACUC AAGAUCCU
1912
AGGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGUUCAGA
11331





2943
CUCAAGAUC CUCAUCCA
2602
UGGAUGAG CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
12018





2946
AAGAUCCUC AUCCACAU
2603
AUGUGGAU CUGAUGAGGCCGUUAGGCCGAA AGGAUCUU
12019





2949
AUCCUCAUC CACAUUGG
2604
CCAAUGUG CUGAUGAGGCCGUUAGGCCGAA AUGAGGAU
12020





2955
AUCCACAUU GGUCACCA
2605
UGGUGACC CUGAUGAGGCCGUUAGGCCGAA AUGUGGAU
12021





2959
ACAUUGGUC ACCAUCUC
2606
GAGAUGGU CUGAUGAGGCCGUUAGGCCGAA ACCAAUGU
12022





2965
GUCACCAUC UCAAUGUG
1920
CACAUUGA CUGAUGAGGCCGUUAGGCCGAA AUGGUGAC
11339





2967
CACCAUCUC AAUGUGGU
1921
ACCACAUU CUGAUGAGGCCGUUAGGCCGAA AGAUGGUG
11340





2982
GUGAACCUC CUAGGCGC
2607
GCGCCUAG CUGAUGAGGCCGUUAGGCCGAA AGGUUCAC
12023





2985
AACCUCCUA GGCGCCUG
2808
CAGGCGCC CUGAUGAGGCCGUUAGGCCGAA AGGAGGUU
12024





3013
GAGGGCCUC UCAUGGUG
2609
CACCAUGA CUGAUGAGGCCGUUAGGCCGAA AGGCCCUC
12025





3015
GGGCCUCUC AUGGUGAU
2610
AUCACCAU CUGAUGAGGCCGUUAGGCCGAA AGAGGCCC
12026





3024
AUGGUGAUU GUGGAAUU
1928
AAUUCCAC CUGAUGAGGCCGUUAGGCCGAA AUCACCAU
11347





3032
UGUGGAAUU CUGCAAGU
2611
ACUUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUCCACA
12027





3033
GUGGAAUUC UGCAAGUU
2612
AACUUGCA CUGAUGAGGCCGUUAGGCCGAA AAUUCCAC
12028





3041
CUGCAAGUU UGGAAACC
2613
GGUUUCCA CUGAUGAGGCCGUUAGGCCGAA ACUUGCAG
12029





3042
UGCAAGUUU GGAAACCU
2614
AGGUUUCC CUGAUGAGGCCGUUAGGCCGAA AACUUGCA
12030





3051
GGAAACCUA UCAACUUA
2615
UAAGUUGA CUGAUGAGGCCGUUAGGCCGAA AGGUUUCC
12031





3053
AAACCUAUC AACUUACU
2616
AGUAAGUU CUGAUGAGGCCGUUAGGCCGAA AUAGGUUU
12032





3058
UAUCAACUU ACUUACGG
2617
CCGUAAGU CUGAUGAGGCCGUUAGGCCGAA AGUUGAUA
12033





3059
AUCAACUUA CUUACGGG
2618
CCCGUAAG CUGAUGAGGCCGUUAGGCCGAA AAGUUGAU
12034





3062
AACUUACUU ACGGGGCA
2619
UGCCCCGU CUGAUGAGGCCGUUAGGCCGAA AGUAAGUU
12035





3063
ACUUACUUA CGGGGCAA
2620
UUGCCCCG CUGAUGAGGCCGUUAGGCCGAA AAGUAAGU
12036





3083
AAAUGAAUU UGUUCCCU
2621
AGGGAACA CUGAUGAGGCCGUUAGGCCGAA AUUCAUUU
12037





3084
AAUGAAUUU GUUCCCUA
2622
UAGGGAAC CUGAUGAGGCCGUUAGGCCGAA AAUUCAUU
12038





3087
GAAUUUGUU CCCUAUAA
2623
UUAUAGGG CUGAUGAGGCCGUUAGGCCGAA ACAAAUUC
12039





3088
AAUUUGUUC CCUAUAAG
2624
CUUAUAGG CUGAUGAGGCCGUUAGGCCGAA AACAAAUU
12040





3092
UGUUCCCUA UAAGAGCA
2625
UGCUCUUA CUGAUGAGGCCGUUAGGCCGAA AGGGAACA
12041





3094
UUCCCUAUA AGAGCAAA
2626
UUUGCUCU CUGAUGAGGCCGUUAGGCCGAA AUAGGGAA
12042





3113
GGCACGCUU CCGCCAGG
2627
CCUGGCGG CUGAUGAGGCCGUUAGGCCGAA AGCGUGCC
12043





3114
GCACGCUUC CGCCAGGG
2628
CCCUGGCG CUGAUGAGGCCGUUAGGCCGAA AAGCGUGC
12044





3131
CAAGGACUA CGUUGGGG
2629
CCCCAACG CUGAUGAGGCCGUUAGGCCGAA AGUCCUUG
12045





3135
GACUACGUU GGGGAGCU
2630
AGCUCCCC CUGAUGAGGCCGUUAGGCCGAA ACGUAGUC
12046





3144
GGGGAGCUC UCCGUGGA
2631
UCCACGGA CUGAUGAGGCCGUUAGGCCGAA AGCUCCCC
12047





3146
GGAGCUCUC CGUGGAUC
2632
GAUCCACG CUGAUGAGGCCGUUAGGCCGAA AGAGCUCC
12048





3154
CCGUGGAUC UGAAAAGA
2633
UCUUUUCA CUGAUGAGGCCGUUAGGCCGAA AUCCACGG
12049





3167
AAGACGCUU GGACAGCA
2634
UGCUGUCC CUGAUGAGGCCGUUAGGCCGAA AGCGUCUU
12050





3177
GACAGCAUC ACCAGCAG
2635
CUGCUGGU CUGAUGAGGCCGUUAGGCCGAA AUGCUGUC
12051





3194
CCAGAGCUC UGCCAGCU
2636
AGCUGGCA CUGAUGAGGCCGUUAGGCCGAA AGCUCUGG
12052





3203
UGCCAGCUC AGGCUUUG
2637
CAAAGCCU CUGAUGAGGCCGUUAGGCCGAA AGCUGGCA
12053





3209
CUCAGGCUU UGUUGAGG
2638
CCUCAACA CUGAUGAGGCCGUUAGGCCGAA AGCCUGAG
12054





3220
UCAGGCUUU GUUGAGGA
2639
UCCUCAAC CUGAUGAGGCCGUUAGGCCGAA AAGCCUGA
12055





3223
GGCUUUGUU GAGGAGAA
2640
UUCUCCUC CUGAUGAGGCCGUUAGGCCGAA ACAAAGCC
12056





3224
GGAGAAAUC GCUCAGUG
2641
CACUGAGC CUGAUGAGGCCGUUAGGCCGAA AUUUCUCC
12057





3228
AAAUCGCUC AGUGAUGU
2642
ACAUCACU CUGAUGAGGCCGUUAGGCCGAA AGCGAUUU
12058





3237
AGUGAUGUA GAGGAAGA
2643
UCUUCCUC CUGAUGAGGCCGUUAGGCCGAA ACAUCACU
9921





3253
AAGAAGCUU CUGAAGAA
2644
UUCUUCAG CUGAUGAGGCCGUUAGGCCGAA AGCUUCUU
12059





3254
AGAAGCUUC UGAAGAAC
2645
GUUCUUCA CUGAUGAGGCCGUUAGGCCGAA AAGCUUCU
12060





3266
AGAACUGUA CAAGGACU
2646
AGUCCUUG CUGAUGAGGCCGUUAGGCCGAA ACAGUUCU
12061





3275
CAAGGACUU CCUGACCU
2647
AGGUCAGG CUGAUGAGGCCGUUAGGCCGAA AGUCCUUG
12062





3276
AAGGACUUC CUGACCUU
1962
AAGGUCAG CUGAUGAGGCCGUUAGGCCGAA AAGUCCUU
11381





3284
CCUGACCUU GGAGCAUC
1963
GAUGCUCC CUGAUGAGGCCGUUAGGCCGAA AGGUCAGG
11382





3292
UGGAGCAUC UCAUCUGU
1964
ACAGAUGA CUGAUGAGGCCGUUAGGCCGAA AUGCUCCA
11383





3294
GACCAUCUC AUCUGUUA
1965
UAACAGAU CUGAUGAGGCCGUUAGGCCGAA AGAUGCUC
11384





3297
CAUCUCAUC UGUUACAG
1966
CUGUAACA CUGAUGAGGCCGUUAGGCCGAA AUGAGAUG
11385





3301
UCAUCUGUU ACAGCUUC
1967
GAAGCUGU CUGAUGAGGCCGUUAGGCCGAA ACAGAUGA
11386





3302
CAUCUGUUA CAGCUUCC
1968
GGAAGCUG CUGAUGAGGCCGUUAGGCCGAA AACAGAUG
11387





3308
UUACAGCUU CCAAGUGG
1969
CCACUUGG CUGAUGAGGCCGUUAGGCCGAA AGCUGUAA
11388





3309
UACAGCUUC CAAGUGGC
1970
GCCACUUG CUGAUGAGGCCGUUAGGCCGAA AAGCUGUA
11389





3319
AAGUGGCUA AGGGCAUG
1971
CAUGCCCU CUGAUGAGGCCGUUAGGCCGAA AGCCACUU
11390





3332
CAUGGAGUU CUUGGCAU
1972
AUGCCAAG CUGAUGAGGCCGUUAGGCCGAA ACUCCAUG
11391





3333
AUGGAGUUC UUGGCAUC
1973
GAUGCCAA CUGAUGAGGCCGUUAGGCCGAA AACUCCAU
11392





3335
GGAGUUCUU GGCAUCAA
2643
UUGAUGCC CUGAUGAGGCCGUUAGGCCGAA AGAACUCC
12063





3341
CUUGGCAUC AAGGAAGU
2649
ACUUCCUU CUGAUGAGGCCGUUAGGCCGAA AUGCCAAG
12064





3352
GGAAGUGUA UCCACAGG
2650
CCUGUGGA CUGAUGAGGCCGUUAGGCCGAA ACACUUCC
12065





3354
AAGUGUAUC CACAGGGA
1977
UCCCUGUG CUGAUGAGGCCGUUAGGCCGAA AUACACUU
11396





3381
CGAAACAUU CUCCUAUC
2651
GAUAGGAG CUGAUGAGGCCGUUAGGCCGAA AUGUUUCG
12066





3382
GAAACAUUC UCCUAUCG
2652
CGAUAGGA CUGAUGAGGCCGUUAGGCCGAA AAUGUUUC
12067





3384
AACAUUCUC CUAUCGGA
2653
UCCGAUAG CUGAUGAGGCCGUUAGGCCGAA AGAAUGUU
12068





3387
AUUCUCCUA UCGGAGAA
2654
UUCUCCGA CUGAUGAGGCCGUUAGGCCGAA AGGAGAAU
12069





3389
UCUCCUAUC GGAGAAGA
2655
UCUUCUCC CUGAUGAGGCCGUUAGGCCGAA AUAGGAGA
12070





3405
AAUGUGGUU AAGAUCUG
2656
CAGAUCUU CUGAUGAGGCCGUUAGGCCGAA ACCACAUU
12071





3406
AUGUGGUUA AGAUCUGU
2657
ACAGAUCU CUGAUGAGGCCGUUAGGCCGAA AACCACAU
12072





3411
GUUAAGAUC UGUGACUU
2658
AAGUCACA CUGAUGAGGCCGUUAGGCCGAA AUCUUAAC
12073





3419
CUGUGACUU CGGCUUGG
2659
CCAAGCCG CUGAUGAGGCCGUUAGGCCGAA AGUCACAG
12074





3420
UGUGACUUC GGCUUGGC
2660
GCCAAGCC CUGAUGAGGCCGUUAGGCCGAA AAGUCACA
11407





3425
CUUCGGCUU GGCCCGGG
2661
CCCGGGCC CUGAUGAGGCCGUUAGGCCGAA AGCCGAAG
12075





3438
CGGGACAUU UAUAAAGA
2662
UCUUUAUA CUGAUGAGGCCGUUAGGCCGAA AUGUCCCG
12076





3439
GGGACAUUU AUAAAGAC
2663
GUCUUUAU CUGAUGAGGCCGUUAGGCCGAA AAUGUCCC
12077





3440
GGACAUUUA UAAAGACC
2664
GGUCUUUA CUGAUGAGGCCGUUAGGCCGAA AAAUGUCC
12078





3442
ACAUUUAUA AAGACCCG
2665
CGGGUCUU CUGAUGAGGCCGUUAGGCCGAA AUAAAUGU
12079





3454
ACCCGGAUU AUGUCAGA
2666
UCUGACAU CUGAUGAGGCCGUUAGGCCGAA AUCCGGGU
12080





3455
CCCGGAUUA UGUCAGAA
2667
UUCUGACA CUGAUGAGGCCGUUAGGCCGAA AAUCCGGG
12081





3459
GAUUAUGUC AGAAAAGG
1998
CCUUUUCU CUGAUGAGGCCGUUAGGCCGAA ACAUAAUC
11417





3480
GCCCGACUC CCUUUGAA
2668
UUCAAAGG CUGAUGAGGCCGUUAGGCCGAA AGUCGGGC
12082





3484
GACUCCCUU UGAAGUGG
2669
CCACUUCA CUGAUGAGGCCGUUAGGCCGAA AGGGAGUC
12083





3485
ACUCCCUUU GAAGUGGA
2670
UCCACUUC CUGAUGAGGCCGUUAGGCCGAA AAGGGAGU
12084





3510
GAAACCAUU UUUGACAG
2671
CUGUCAAA CUGAUGAGGCCGUUAGGCCGAA AUGGUUUC
12085





3511
AAACCAUUU UUGACAGA
2672
UCUGUCAA CUGAUGAGGCCGUUAGGCCGAA AAUGGUUU
12086





3512
AACCAUUUU UGACAGAG
2673
CUCUGUCA CUGAUGAGGCCGUUAGGCCGAA AAAUGGUU
12087





3513
ACCAUUUUU GACAGAGU
2674
ACUCUGUC CUGAUGAGGCCGUUAGGCCGAA AAAAUGGU
12088





3522
GACAGAGUA UACACAAU
2675
AUUGUGUA CUGAUGAGGCCGUUAGGCCGAA ACUCUGUC
12089





3524
CAGAGUAUA CACAAUUC
2676
GAAUUGUG CUGAUGAGGCCGUUAGGCCGAA AUACUCUG
12090





3531
UACACAAUU CAGAGCGA
2677
UCGCUCUG CUGAUGAGGCCGUUAGGCCGAA AUUGUGUA
12091





3532
ACACAAUUC AGAGCGAU
2678
AUCGCUCU CUGAUGAGGCCGUUAGGCCGAA AAUUGUGU
12092





3548
UGUGUGGUC UUUCGGUG
2679
CACCGAAA CUGAUGAGGCCGUUAGGCCGAA ACCACACA
12093





3550
UGUGGUCUU UCGGUGUG
2680
CACACCGA CUGAUGAGGCCGUUAGGCCGAA AGACCACA
12094





3551
GUGGUCUUU CGGUGUGU
2681
ACACACCG CUGAUGAGGCCGUUAGGCCGAA AAGACCAC
12095





3552
UGGUCUUUC GGUGUGUU
2682
AACACACC CUGAUGAGGCCGUUAGGCCGAA AAAGACCA
12096





3560
CGGUGUGUU GCUCUGGG
2683
CCCAGAGC CUGAUGAGGCCGUUAGGCCGAA ACACACCG
12097





3564
GUGUUGCUC UGGGAAAU
2684
AUUUCCCA CUGAUGAGGCCGUUAGGCCGAA AGCAACAC
12098





3573
UGGGAAAUA UUUUCCUU
2017
AAGGAAAA CUGAUGAGGCCGUUAGGCCGAA AUUUCCCA
11436





3575
GGAAAUAUU UUCCUUAG
2018
CUAAGGAA CUGAUGAGGCCGUUAGGCCGAA AUAUUUCC
11437





3576
GAAAUAUUU UCCUUAGG
2019
CCUAAGGA CUGAUGAGGCCGUUAGGCCGAA AAUAUUUC
11438





3577
AAAUAUUUU CCUUAGGU
2020
ACCUAAGG CUGAUGAGGCCGUUAGGCCGAA AAAUAUUU
11439





3578
AAUAUUUUC CUUAGGUG
2021
CACCUAAG CUGAUGAGGCCGUUAGGCCGAA AAAAUAUU
11440





3581
AUUUUCCUU AGGUGCCU
2685
AGGCACCU CUGAUGAGGCCGUUAGGCCGAA AGGAAAAU
12099





3582
UUUUCCUUA GGUGCCUC
2686
GAGGCACC CUGAUGAGGCCGUUAGGCCGAA AAGGAAAA
12100





3590
AGGUGCCUC CCCAUACC
2687
GGUAUGGG CUGAUGAGGCCGUUAGGCCGAA AGGCACCU
12101





3596
CUCCCCAUA CCCUGGGG
2688
CCCCAGGG CUGAUGAGGCCGUUAGGCCGAA AUGGGGAG
12102





3606
CCUGGGGUC AAGAUUGA
2689
UCAAUCUU CUGAUGAGGCCGUUAGGCCGAA ACCCCAGG
11448





3612
GUCAAGAUU GAUGAAGA
2690
UCUUCAUC CUGAUGAGGCCGUUAGGCCGAA AUCUUGAC
12103





3623
UGAAGAAUU UUGUAGGA
2691
UCCUACAA CUGAUGAGGCCGUUAGGCCGAA AUUCUUCA
12104





3624
GAAGAAUUU UGUAGGAG
2692
CUCCUACA CUGAUGAGGCCGUUAGGCCGAA AAUUCUUC
12105





3625
AAGAAUUUU GUAGGAGA
2693
UCUCCUAC CUGAUGAGGCCGUUAGGCCGAA AAAUUCUU
12106





3628
AAUUUUGUA GGAGAUUG
2694
CAAUCUCC CUGAUGAGGCCGUUAGGCCGAA ACAAAAUU
12107





3635
UAGGAGAUU GAAAGAAG
2695
CUUCUUUC CUGAUGAGGCCGUUAGGCCGAA AUCUCCUA
12108





3649
AAGGAACUA GAAUGCGG
2696
CCGCAUUC CUGAUGAGGCCGUUAGGCCGAA AGUUCCUU
12109





3661
UGCGGGCUC CUGACUAC
2697
GUAGUCAG CUGAUGAGGCCGUUAGGCCGAA AGCCCGCA
12110





3668
UCCUGACUA CACUACCC
2698
GGGUAGUG CUGAUGAGGCCGUUAGGCCGAA AGUCAGGA
12111





3673
ACUACACUA CCCCAGAA
2699
UUCUGGGG CUGAUGAGGCCGUUAGGCCGAA AGUGUAGU
12112





3686
AGAAAUGUA CCAGACCA
2041
UGGUCUGG CUGAUGAGGCCGUUAGGCCGAA ACAUUUCU
11460





3734
GAGACCCUC GUUUUCAG
2700
CUGAAAAC CUGAUGAGGCCGUUAGGCCGAA AGGGUCUC
12113





3737
ACCCUCGUU UUCAGAGU
2701
ACUCUGAA CUGAUGAGGCCGUUAGGCCGAA ACGAGGGU
12114





3738
CCCUCGUUU UCAGAGUU
2702
AACUCUGA CUGAUGAGGCCGUUAGGCCGAA AACGAGGG
12115





3739
CCUCGUUUU CAGAGUUG
2703
CAACUCUG CUGAUGAGGCCGUUAGGCCGAA AAACGAGG
12116





3740
CUCGUUUUC AGAGUUGG
2704
CCAACUCU CUGAUGAGGCCGUUAGGCCGAA AAAACGAG
12117





3746
UUCAGAGUU GGUGGAGC
2705
GCUCCACC CUGAUGAGGCCGUUAGGCCGAA ACUCUGAA
12118





3757
UGGAGCAUU UGGGAAAC
2706
GUUUCCCA CUGAUGAGGCCGUUAGGCCGAA AUGCUCCA
12119





3758
GGAGCAUUU GGGAAACC
2707
GGUUUCCC CUGAUGAGGCCGUUAGGCCGAA AAUGCUCC
12120





3768
GGAAACCUC CUGCAAGC
2708
GCUUGCAG CUGAUGAGGCCGUUAGGCCGAA AGGUUUCC
12121





3803
CAAAGACUA UAUUGUUC
2709
GAACAAUA CUGAUGAGGCCGUUAGGCCGAA AGUCUUUG
12122





3805
AAGACUAUA UUGUUCUU
2710
AAGAACAA CUGAUGAGGCCGUUAGGCCGAA AUAGUCUU
12123





3807
GACUAUAUU GUUCUUCC
2711
GGAAGAAC CUGAUGAGGCCGUUAGGCCGAA AUAUAGUC
12124





3810
UAUAUUGUU CUUCCAAU
2712
AUUGGAAG CUGAUGAGGCCGUUAGGCCGAA ACAAUAUA
12125





3811
AUAUUGUUC UUCCAAUG
2713
CAUUGGAA CUGAUGAGGCCGUUAGGCCGAA AACAAUAU
12126





3813
AUUGUUCUU CCAAUGUC
2714
GACAUUGG CUGAUGAGGCCGUUAGGCCGAA AGAACAAU
12127





3814
UUGUUCUUC CAAUGUCA
2715
UGACAUUG CUGAUGAGGCCGUUAGGCCGAA AAGAACAA
12128





3821
UCCAAUGUC AGAGACAC
2716
GUGUCUCU CUGAUGAGGCCGUUAGGCCGAA ACAGUGGA
12129





3847
AAGAGGAUU CUGGACUC
2065
GAGUCCAG CUGAUGAGGCCGUUAGGCCGAA AUCCUCUU
11484





3848
AGAGGAUUC UGGACUCU
2066
AGAGUCCA CUGAUGAGGCCGUUAGGCCGAA AAUCCUCU
11485





3855
UCUGGACUC UCCCUGCC
2717
GGCAGGGA CUGAUGAGGCCGUUAGGCCGAA AGUCCAGA
12130





3857
UGGACUCUC CCUGCCUA
2718
UAGGCAGG CUGAUGAGGCCGUUAGGCCGAA AGAGUCCA
12131





3865
CCCUGCCUA CCUCACCU
2719
AGGUGAGG CUGAUGAGGCCGUUAGGCCGAA AGGCAGGG
12132





3869
GCCUACCUC ACCUGUUU
2071
AAACAGGU CUGAUGAGGCCGUUAGGCCGAA AGGUAGGC
11490





3876
UCACCUGUU UCCUGUAU
2072
AUACAGGA CUGAUGAGGCCGUUAGGCCGAA ACAGGUGA
11491





3877
CACCUGUUU CCUGUAUG
2073
CAUACAGG CUGAUGAGGCCGUUAGGCCGAA AACAGGUG
11492





3878
ACCUGUUUC CUGUAUGG
2074
CCAUACAG CUGAUGAGGCCGUUAGGCCGAA AAACAGGU
11493





3883
UUUCCUGUA UGGAGGAA
2720
UUCCUCCA CUGAUGAGGCCGUUAGGCCGAA ACAGGAAA
12133





3914
CCCCAAAUU CCAUUAUG
2077
CAUAAUGG CUGAUGAGGCCGUUAGGCCGAA AUUUGGGG
11496





3915
CCCAAAUUC CAUUAUGA
2078
UCAUAAUG CUGAUGAGGCCGUUAGGCCGAA AAUUUGGG
11497





3919
AAUUCCAUU AUGACAAC
2079
GUUGUCAU CUGAUGAGGCCGUUAGGCCGAA AUGGAAUU
11498





3920
AUUCCAUUA UGACAACA
2080
UGUUGUCA CUGAUGAGGCCGUUAGGCCGAA AAUGGAAU
11499





3939
GCAGGAAUC AGUCAUUA
2721
UAAUGACU CUGAUGAGGCCGUUAGGCCGAA AUUCCUGC
12134





3943
GAAUCAGUC AUUAUCUC
2722
GAGAUAAU CUGAUGAGGCCGUUAGGCCGAA ACUGACUC
12135





3946
UCAGUCAUU AUCUCCAG
2723
CUGGAGAU CUGAUGAGGCCGUUAGGCCGAA AUGACUGA
12136





3947
CAGUCAUUA UCUCCAGA
2724
UCUGGAGA CUGAUGAGGCCGUUAGGCCGAA AAUGACUG
12137





3949
GUCAUUAUC UCCAGAAC
2725
GUUCUGGA CUGAUGAGGCCGUUAGGCCGAA AUAAUGAC
12138





3951
CAUUAUCUC CAGAACAG
2726
CUGUUCUG CUGAUGAGGCCGUUAGGCCGAA AGAUAAUG
12139





3961
AGAACAGUA AGCGAAAG
2085
CUUUCGCU CUGAUGAGGCCGUUAGGCCGAA ACUGUUCU
11504





3987
GUGAGUGUA AAAACAUU
2086
AAUGUUUU CUGAUGAGGCCGUUAGGCCGAA ACACUCAC
11505





3995
AAAAACAUU UGAAGAUA
2087
UAUCUUCA CUGAUGAGGCCGUUAGGCCGAA AUGUUUUU
11506





3996
AAAACAUUU GAAGAUAU
2088
AUAUCUUC CUGAUGAGGCCGUUAGGCCGAA AAUGUUUU
11507





4003
UUGAAGAUA UCCCAUUG
2727
CAAUGGGA CUGAUGAGGCCGUUAGGCCGAA AUCUUCAA
12140





4005
GAAGAUAUC CCAUUGGA
2728
UCCAAUGG CUGAUGAGGCCGUUAGGCCGAA AUAUCUUC
12141





4010
UAUCCCAUU GGAGGAAC
2729
GUUCCUCC CUGAUGAGGCCGUUAGGCCGAA AUGGGAUA
12142





4026
CCAGAAGUA AAAGUGAU
2730
AUCACUUU CUGAUGAGGCCGUUAGGCCGAA ACUUCUGG
12143





4039
AAAGUGAUC CCAGAUGA
2731
UCAUCUGG CUGAUGAGGCCGUUAGGCCGAA AUCACUUU
12144





4068
GGGAUGGUC CUUGCAUC
2732
GAUGCAAG CUGAUGAGGCCGUUAGGCCGAA ACCAUCCC
12145





4071
AUGGUCCUU GCAUCAGA
2733
UCUGAUGC CUGAUGAGGCCGUUAGGCCGAA AGGACCAU
12146





4076
CCUUGCAUC AGAAGAGC
2734
GCUCUUCU CUGAUGAGGCCGUUAGGCCGAA AUGCAAGG
12147





4093
UGAAAACUC UGGAAGAC
2735
GUCUUCCA CUGAUGAGGCCGUUAGGCCGAA AGUUUUCA
11520





4112
GAACAAAUU AUCUCCAU
2736
AUGGAGAU CUGAUGAGGCCGUUAGGCCGAA AUUUGUUC
12148





4113
AACAAAUUA UCUCCAUC
2737
GAUGGAGA CUGAUGAGGCCGUUAGGCCGAA AAUUUGUU
12149





4115
CAAAUUAUC UCCAUCUG
2105
AAGAUGGA CUGAUGAGGCCGUUAGGCCGAA AUAAUUEU
11524





4117
AAUUAUCUC CAUCUUUU
2106
AAAAGAUG CUGAUGAGGCCGUUAGGCCGAA AGAUAAUU
11525





4121
AUCUCCAUC UUUUGGUG
2107
CACCAAAA CUGAUGAGGCCGUUAGGCCGAA AUGGAGAW
11526





4123
CUCCAUCUU UUGGUGGA
2108
UCCACCAA CUGAUGAGGCCGUUAGGCCGAA AGAUGGAG
11527





4124
UCCAUCUUU UGGUGGAA
2109
UUCCACCA CUGAUGAGGCCGUUAGGCCGAA AAGAUGGA
11528





4125
CCAUCUUUU GGUGGAAU
2110
AUUCCACC CUGAUGAGGCCGUUAGGCCGAA AAAGAUGG
11529





4144
UGCCCAGUA AAAGCAGG
2738
CCUGCUUU CUGAUGAGGCCGUUAGGCCGAA ACUGGGCA
12150





4157
CAGGGAGUC UGUGGCCU
2739
AGGOCACA CUGAUGAGGCCGUUAGGCCGAA ACUCCCUG
12151





4166
UGUGGCCUC GGAAGGCU
2740
AGCCUUCC CUGAUGAGGCCGUUAGGCCGAA AGGCCACA
12152





4175
GGAAGGCUC CAACCAGA
2741
UCUGGUUG CUGAUGAGGCCGUUAGGCCGAA AGCCUUCC
12153





4193
CAGUGGCUA CCAGUCUG
2742
CAGACUGG CUGAUGAGGCCGUUAGGCCGAA AGCCACUG
12154





4199
CUACCAGUC UGGGUAUC
2743
GAUACCCA CUGAUGAGGCCGUUAGGCCGAA ACUGGUAG
12155





4205
GUCUGGGUA UCACUCAG
2744
CUGAGUGA CUGAUGAGGCCGUUAGGCCGAA ACCCAGAC
12156





4207
CUGGGUAUC ACUCAGAU
2745
AUCUGAGU CUGAUGAGGCCGUUAGGCCGAA AUACCCAG
12157





4211
GUAUCACUC AGAUGACA
2746
UGUCAUCU CUGAUGAGGCCGUUAGGCCGAA AGUGAUAC
12158





4235
CACCGUGUA CUCCAGCG
2747
CGCUGGAG CUGAUGAGGCCGUUAGGCCGAA ACACGGUG
12159





4238
CGUGUACUC CAGCGACG
2748
CGUCGCUG CUGAUGAGGCCGUUAGGCCGAA AGUACACG
12160





4257
GCAGGACUU UUAAAGAU
2749
AUCUUUAA CUGAUGAGGCCGUUAGGCCGAA AGUCCUGC
12161





4258
CAGGACUUU UAAAGAUG
2750
CAUCUUUA CUGAUGAGGCCGUUAGGCCGAA AAGUCCUG
12162





4259
AGGACUUUU AAAGAUGG
2751
CCAUCUUU CUGAUGAGGCCGUUAGGCCGAA AAAGUCCU
12163





4260
GGACUUUUA AAGAUGGU
2752
ACCAUCUG CUGAUGAGGCCGUUAGGCCGAA AAAAGUCC
12164





4281
GCUGCAGUU CACGCUGA
2753
UCAGCGUG CUGAUGAGGCCGUUAGGCCGAA ACUGCAGC
12165





4282
CUGCAGUUC ACGCUGAC
2754
GUCAGCGU CUGAUGAGGCCGUUAGGCCGAA AACUGCAG
12166





4292
CGCUGACUC AGGGACCA
2755
UGGUCCCU CUGAUGAGGCCGUUAGGCCGAA AGUCAGCG
12167





4311
CUGCAGCUC ACCUCCUG
2756
CAGGAGGU CUGAUGAGGCCGUUAGGCCGAA AGCUGCAG
12168





4316
GCUCACCUC CUGUUUAA
2757
UUAAACAG CUGAUGAGGCCGUUAGGCCGAA AGGUGAGC
12169





4321
CCUCCUGUU UAAAUGGA
2758
UCCAUUUA CUGAUGAGGCCGUUAGGCCGAA ACAGGAGG
12170





4322
CUCCUGUUU AAAUGGAA
2759
UUCCAUUU CUGAUGAGGCCGUUAGGCCGAA AACAGGAG
12171





4323
UCCUGUUUA AAUGGAAG
2760
CUUCCAUU CUGAUGAGGCCGUUAGGCCGAA AAACAGGA
12172





4336
GAAGUGGUC CUGUCCCG
2761
CGGGACAG CUGAUGAGGCCGUUAGGCCGAA ACCACUUC
12173





4341
GGUCCUGUC CCGGCUCC
2762
GGAGCCGG CUGAUGAGGCCGUUAGGCCGAA ACAGGACC
12174





4348
UCCCGGCUC CGCCCCCA
2763
UGGGGGCG CUGAUGAGGCCGUUAGGCCGAA AGCCGGGA
12175





4360
CCCCAACUC CUGGAAAU
2764
AUUUCCAG CUGAUGAGGCCGUUAGGCCGAA AGUUGGGG
12176





4369
CUGGAAAUC ACGAGAGA
2765
UCUCUCGU CUGAUGAGGCCGUUAGGCCGAA AUUUCCAG
12177





4387
GUGCUGCUU AGAUUUUC
2766
GAAAAUCU CUGAUGAGGCCGUUAGGCCGAA AGCAGCAC
12178





4388
UGCUGCUUA GAUUUUCA
2767
UGAAAAUC CUGAUGAGGCCGUUAGGCCGAA AAGCAGCA
12179





4392
GCUUAGAUU UUCAAGUG
2768
CACUUGAA CUGAUGAGGCCGUUAGGCCGAA AUCUAAGC
12180





4393
CUUAGAUUU UCAAGUGU
2769
ACACUUGA CUGAUGAGGCCGUUAGGCCGAA AAUCUAAG
12181





4394
UUAGAUUUU CAAGUGUU
2770
AACACUUG CUGAUGAGGCCGUUAGGCCGAA AAAUCUAA
12182





4395
UAGAUUTUU AAGUGUUG
2771
CAACACUG CUGAUGAGGCCGUUAGGCCGAA AAAAUCUA
12183





4402
UCAAGUGUU GUUCUUUC
2772
GAAAGAAC CUGAUGAGGCCGUUAGGCCGAA ACACUUGA
12184





4405
AGUGUUGUU CUUUCCAC
2146
GUGGAAAG CUGAUGAGGCCGUUAGGCCGAA ACAACACU
11565





4406
GUGUUGUUC UUUCCACC
2147
GGUGGAAA CUGAUGAGGCCGUUAGGCCGAA AACAACAC
11566





4408
GUUGUUCUU UCCACCAC
2773
GUGGUGGA CUGAUGAGGCCGUUAGGCCGAA AGAACAAC
12185





4409
UUGUUCUUU CCACCACC
2774
GGUGGUGG CUGAUGAGGCCGUUAGGCCGAA AAGAACAA
12186





4410
UGUUCUUUC CACCACCC
2775
GGGUGGUG CUGAUGAGGCCGUUAGGCCGAA AAAGAACA
12187





4425
CCGGAAGUA GCCACAUU
2776
AAUGUGGC CUGAUGAGGCCGUUAGGCCGAA ACUUCCGG
12188





4433
AGCCACAUU UGAUUCUC
2777
GAAAAUCA CUGAUGAGGCCGUUAGGCCGAA AUGUGGCU
12189





4434
GCCACAUUU GAUUUUCA
2778
UGAAAAUC CUGAUGAGGCCGUUAGGCCGAA AAUGUGGC
12190





4438
CAUUUGAUU UUCAUUUU
2779
AAAAUGAA CUGAUGAGGCCGUUAGGCCGAA AUCAAAUG
12191





4439
AUUUGAUUU UCAUUUUU
2780
AAAAAUGA CUGAUGAGGCCGUUAGGCCGAA AAUCAAAU
12192





4440
UUUGAUUUU CAUUUUUG
2781
CAAAAAUG CUGAUGAGGCCGUUAGGCCGAA AAAUCAAA
12193





4441
UUGAUUUUC AUUUUUGG
2782
CCAAAAAU CUGAUGAGGCCGUUAGGCCGAA AAAAUCAA
12194





4444
AUUUUCAUU UUUGGAGG
2783
CCUCCAAA CUGAUGAGGCCGUUAGGCCGAA AUGAAAAU
12195





4445
UUUUCAUUU UUGGAGGA
2784
UCCUCCAA CUGAUGAGGCCGUUAGGCCGAA AAUGAAAA
12196





4446
UUUCAUUUU UGGAGGAG
2785
CUCCUCCA CUGAUGAGGCCGUUAGGCCGAA AAAUGAAA
12197





4447
UUCAUUUUU GGAGGAGG
2786
CCUCCUCC CUGAUGAGGCCGUUAGGCCGAA AAAAUGAA
12198





4461
AGGGACCUC AGACUGCA
2787
UCCAGUCU CUGAUGAGGCCGUUAGGCCGAA AGGUCCCU
12199





4477
AAGGAGCUU GUCCUCAG
2788
CUGAGGAC CUGAUGAGGCCGUUAGGCCGAA AGCUCCUU
12200





4480
GAGCUUGUC CUCAGGGC
2789
GCCCUGAG CUGAUGAGGCCGUUAGGCCGAA ACAAGCUC
12201





4483
CUUGUCCUC AGGGCAUU
2790
AAUGCCCU CUGAUGAGGCCGUUAGGCCGAA AGGACAAG
12202





4491
CAGGGCAUU UCCAGAGA
2791
UCUCUGGA CUGAUGAGGCCGUUAGGCCGAA AUGCCCUG
12203





4492
AGGGCAUUU CCAGAGAA
2792
UUCUCUGG CUGAUGAGGCCGUUAGGCCGAA AAUGCCCU
12204





4493
GGGCAUUUC CAGAGAAG
2793
CUUCUCUG CUGAUGAGGCCGUUAGGCCGAA AAAUGCCC
12205





4525
GAAUGUGUU GACUCUAC
2794
GUAGAGUC CUGAUGAGGCCGUUAGGCCGAA ACACAUUC
12206





4530
UGUUGACUC UACUCUCU
2795
AGAGAGUA CUGAUGAGGCCGUUAGGCCGAA AGUCAACA
12207





4532
UUGACUCUA CUCUCUUU
2796
AAAGAGAG CUGAUGAGGCCGUUAGGCCGAA AGAGUCAA
12208





4535
ACUCUACUC UCUUUUCC
2797
GGAAAAGA CUGAUGAGGCCGUUAGGCCGAA AGUAGAGU
12209





4537
UCUACUCUC UUUUCCAU
2798
AUGGAAAA CUGAUGAGGCCGUUAGGCCGAA AGAGUAGA
12210





4539
UACUCUCUU UUCCAUUC
2799
GAAUGGAA CUGAUGAGGCCGUUAGGCCGAA AGAGAGUA
12211





4540
ACUCUCUUU UCCAUUCA
2800
UGAAUGGA CUGAUGAGGCCGUUAGGCCGAA AAGAGAGU
12212





4541
CUCUCUUUU CCAUUCAU
2801
AUGAAUGG CUGAUGAGGCCGUUAGGCCGAA AAAGAGAG
12213





4542
UCUCUUUUC CAUUCAUU
2802
AAUGAAUG CUGAUGAGGCCGUUAGGCCGAA AAAAGAGA
12214





4546
UUUUCCAUU CAUUUAAA
2803
UUUAAAUG CUGAUGAGGCCGUUAGGCCGAA AUGGAAAA
12215





4547
UUUCCAUUC AUUUAAAA
2804
UUUUAAAU CUGAUGAGGCCGUUAGGCCGAA AAUGGAAA
12216





4550
CCAUUCAUU UAAAAGUC
2805
GACUUUUA CUGAUGAGGCCGUUAGGCCGAA AUGAAUGG
12217





4551
CAUUCAUUU AAAAGUCC
2806
GGACUUUU CUGAUGAGGCCGUUAGGCCGAA AAUGAAUG
12218





4552
AUUCAUUUA AAAGUCCU
2807
AGGACUUU CUGAUGAGGCCGUUAGGCCGAA AAAUGAAU
12219





4558
UUAAAAGUC CUAUAUAA
2808
UUAUAUAG CUGAUGAGGCCGUUAGGCCGAA ACUUUUAA
12220





4561
AAAGUCCUA UAUAAUGU
2809
ACAUUAUA CUGAUGAGGCCGUUAGGCCGAA AGGACUUU
12221





4563
AGUCCUAUA UAAUGUGC
2810
GCACAUUA CUGAUGAGGCCGUUAGGCCGAA AUAGGACU
12222





4565
UCCUAUAUA AUGUGCCC
2811
GGGCACAU CUGAUGAGGCCGUUAGGCCGAA AUAUAGGA
12223





4583
GCUGUGGUC UCACUACC
2812
GGUAGUGA CUGAUGAGGCCGUUAGGCCGAA ACCACAGC
12224





4585
UGUGGUCUC ACUACCAG
2813
CUGGUAGU CUGAUGAGGCCGUUAGGCCGAA AGACCACA
12225





4589
GUCUCACUA CCAGUUAA
2814
UUAACUGG CUGAUGAGGCCGUUAGGCCGAA AGUGAGAC
12226





4595
CUACCAGUU AAAGCAAA
2815
UUUGCUUU CUGAUGAGGCCGUUAGGCCGAA ACUGGUAG
12227





4596
UACCAGUUA AAGCAAAA
2816
UUUUGCUU CUGAUGAGGCCGUUAGGCCGAA AACUGGUA
12228





4609
AAAAGACUU UCAAACAC
2817
GUGUUUGA CUGAUGAGGCCGUUAGGCCGAA AGUCUUUU
12229





4610
AAAGACUUU CAAACACG
2818
CGUGUUUG CUGAUGAGGCCGUUAGGCCGAA AAGUCUUU
12230





4611
AAGACUUUC AAACACGU
2819
ACGUGUUU CUGAUGAGGCCGUUAGGCCGAA AAAGUCUU
12231





4625
CGUGGACUC UGUCCUCC
2820
GGAGGACA CUGAUGAGGCCGUUAGGCCGAA AGUCCACG
12232





4629
GACUCUGUC CUCCAAGA
2821
UCUUGGAG CUGAUGAGGCCGUUAGGCCGAA ACAGAGUC
12233





4632
UCUGUCCUC CAAGAAGU
2822
ACUUCUUG CUGAUGAGGCCGUUAGGCCGAA AGGACAGA
12234





4654
CGGCACCUC UGUGAAAC
2823
GUUUCACA CUGAUGAGGCCGUUAGGCCGAA AGGUGCCG
12235





4668
AACUGGAUC GAAUGGGC
2824
GCCCAUUC CUGAUGAGGCCGUUAGGCCGAA AUCCAGUU
12236





4683
GCAAUGCUU UGUGUGUU
2825
AACACACA CUGAUGAGGCCGUUAGGCCGAA AGCAUUGC
12237





4684
CAAUGCUUU GUGUGUUG
2826
CAACACAC CUGAUGAGGCCGUUAGGCCGAA AAGCAUUG
12238





4691
UUGUGUGUU GAGGAUGG
2827
CCAUCCUC CUGAUGAGGCCGUUAGGCCGAA ACACACAA
12239





4709
UGAGAUGUC CCAGGGCC
2828
GGCCCUGG CUGAUGAGGCCGUUAGGCCGAA ACAUCUCA
12240





4722
GGCCGAGUC UGUCUACC
2829
GGUAGACA CUGAUGAGGCCGUUAGGCCGAA ACUCGGCC
12241





4726
GAGUCUGUC UACCUUGG
2830
CCAAGGUA CUGAUGAGGCCGUUAGGCCGAA ACAGACUC
12242





4728
GUCUGUCUA CCUUGGAG
2831
CUCCAAGG CUGAUGAGGCCGUUAGGCCGAA AGACAGAC
12243





4732
GUCUACCUU GGAGGCUU
2832
AAGCCUCC CUGAUGAGGCCGUUAGGCCGAA AGGUAGAC
12244





4740
UGGAGGCUU UGUGGAGG
2833
CCUCCACA CUGAUGAGGCCGUUAGGCCGAA AGCCUCCA
12245





4741
GGAGGCUUU GUGGAGGA
2834
UCCUCCAC CUGAUGAGGCCGUUAGGCCGAA AAGCCUCC
12246





4758
UGCGGGCUA UGAGCCAA
2835
UUGGCUCA CUGAUGAGGCCGUUAGGCCGAA AGCCCGCA
12247





4771
CCAAGUGUU AAGUGUGG
2836
CCACACUU CUGAUGAGGCCGUUAGGCCGAA ACACUUGG
12248





4772
CAAGUGUUA AGUGUGGG
2837
CCCACACU CUGAUGAGGCCGUUAGGCCGAA AACACUUG
12249





4811
GCGCAAGUC GCUCGGAG
2838
CUCCGAGC CUGAUGAGGCCGUUAGGCCGAA ACUUGCGC
12250





4815
AAGUCGCUC GGAGAGCG
2839
CGCUCUCC CUGAUGAGGCCGUUAGGCCGAA AGCGACUU
12251





4826
AGAGCGGUU GGAGCCUG
2840
CAGGCUCC CUGAUGAGGCCGUUAGGCCGAA ACCGCUCU
12252





4844
AGAUGCAUU GUGCUGGC
2841
GCCAGCAC CUGAUGAGGCCGUUAGGCCGAA AUGCAUCU
12253





4854
UGCUGGCUC UGGUGGAG
2842
CUCCACCA CUGAUGAGGCCGUUAGGCCGAA AGCCAGCA
12254





4870
GGUGGGCUU GUGGCCUG
2843
CAGGCCAC CUGAUGAGGCCGUUAGGCCGAA AGCCCACC
12255





4880
UGGCCUGUC AGGAAACG
2844
CGUUUCCU CUGAUGAGGCCGUUAGGCCGAA ACAGGCCA
12256





4908
GGCAGGGUU UGGUUUUG
2845
CAAAACCA CUGAUGAGGCCGUUAGGCCGAA ACCCUGCC
12257





4909
GCAGGGUUU GGUUUUGG
2846
CCAAAACC CUGAUGAGGCCGUUAGGCCGAA AACCCUGC
12258





4913
GGUUUGGUU UUGGAAGG
2847
CCUUCCAA CUGAUGAGGCCGUUAGGCCGAA ACCAAACC
12259





4914
GUUUGGUUU UGGAAGGU
2848
ACCUUCCA CUGAUGAGGCCGUUAGGCCGAA AACCAAAC
12260





4915
UUUGGUUUU GGAAGGUU
2849
AACCUUCC CUGAUGAGGCCGUUAGGCCGAA AAACCAAA
12261





4923
UGGAAGGUU UGCGUGCU
2850
AGCACGCA CUGAUGAGGCCGUUAGGCCGAA ACCUUCCA
12262





4924
GGAAGGUUU GCGUGCUC
2851
GAGCACGC CUGAUGAGGCCGUUAGGCCGAA AACCUUCC
12263





4932
UGCGUGCUC UUCACAGU
2852
ACUGUGAA CUGAUGAGGCCGUUAGGCCGAA AGCACGCA
12264





4934
CGUGCUCUU CACAGUCG
2853
CGACUGUG CUGAUGAGGCCGUUAGGCCGAA AGAGCACG
12265





4935
GUGCUCUUC ACAGUCGG
2854
CCGACUGU CUGAUGAGGCCGUUAGGCCGAA AAGAGCAC
12266





4941
UUCACAGUC GGGUUACA
2855
UGUAACCC CUGAUGAGGCCGUUAGGCCGAA ACUGUGAA
12267





4946
AGUCGGGUU ACAGGCGA
2856
UCGCCUGU CUGAUGAGGCCGUUAGGCCGAA ACCCGACU
12268





4947
GUCGGGUUA CAGGCGAG
2857
CUCGCCUG CUGAUGAGGCCGUUAGGCCGAA AACCCGAC
12269





4957
AGGCGAGUU CCCUGUGG
2858
CCACAGGG CUGAUGAGGCCGUUAGGCCGAA ACUCGCCU
12270





4958
GGCGAGUUC CCUGUGGC
2859
GCCACAGG CUGAUGAGGCCGUUAGGCCGAA AACUCGCC
12271





4969
UGUGGCGUU UCCUACUC
2860
GAGUAGGA CUGAUGAGGCCGUUAGGCCGAA ACGCCACA
12272





4970
GUGGCGUUU CCUACUCC
2861
GGAGUAGG CUGAUGAGGCCGUUAGGCCGAA AACGCCAC
12273





4971
UGGCGUUUC CUACUCCU
2862
AGGAGUAG CUGAUGAGGCCGUUAGGCCGAA AAACGCCA
12274





4974
CGUUUCCUA CUCCUAAU
2863
AUUAGGAG CUGAUGAGGCCGUUAGGCCGAA AGGAAACG
12275





4977
UUCCUACUC CUAAUGAG
2864
CUCAUUAG CUGAUGAGGCCGUUAGGCCGAA AGUAGGAA
12276





4980
CUACUCCUA AUGAGAGU
2865
ACUCUCAU CUGAUGAGGCCGUUAGGCCGAA AGGAGUAG
12277





4989
AUGAGAGUU CCUUCCGG
2866
CCGGAAGG CUGAUGAGGCCGUUAGGCCGAA ACUCUCAU
12278





4990
UGAGAGUUC CUUCCGGA
2867
UCCGGAAG CUGAUGAGGCCGUUAGGCCGAA AACUCUCA
12279





4993
GAGUUCCUU CCGGACUC
2868
GAGUCCGG CUGAUGAGGCCGUUAGGCCGAA AGGAACUC
12280





4994
AGUUCCUUC CGGACUCU
2869
AGAGUCCG CUGAUGAGGCCGUUAGGCCGAA AAGGAACU
12281





5001
UCCGGACUC UUACGUGU
2870
ACACGUAA CUGAUGAGGCCGUUAGGCCGAA AGUCCOGA
12282





5003
CGGACUCUU ACGUGUCU
2871
AGACACGU CUGAUGAGGCCGUUAGGCCGAA AGAGUCCG
12283





5004
GGACUCUUA CGUGUCUC
2872
GAGACACG CUGAUGAGGCCGUUAGGCCGAA AAGAGUCC
12284





5010
UUACGUGUC UCCUGGCC
2873
GGCCAGGA CUGAUGAGGCCGUUAGGCCGAA ACACGUAA
12285





5012
ACGUGUCUC CUGGCCUG
2874
CAGGCCAG CUGAUGAGGCCGUUAGGCCGAA AGACACGU
12286





5046
AUGCAGCUU GCUCCUUC
2875
GAAGGAGC CUGAUGAGGCCGUUAGGCCGAA AGCUGCAU
12287





5050
AGCUUGCUC CUUCCUCA
2876
UGAGGAAG CUGAUGAGGCCGUUAGGCCGAA AGCAAGCU
12288





5053
UUGCUCCUU CCUCAUCU
2877
AGAUGAGG CUGAUGAGGCCGUUAGGCCGAA AGGAGCAA
12289





5054
UGCUCCUUC CUCAUCUC
2878
GAGAUGAG CUGAUGAGGCCGUUAGGCCGAA AAGGAGCA
12290





5057
UCCUUCCUC AUCUCUCA
2879
UGAGAGAU CUGAUGAGGCCGUUAGGCCGAA AGGAAGGA
12291





5b60
UUCCUCAUC UCUCAGGC
2880
GCCUGAGA CUGAUGAGGCCGUUAGGCCGAA AUGAGGAA
12292





5062
CCUCAUCUC UCAGGCUG
2881
CAGCCUGA CUGAUGAGGCCGUUAGGCCGAA AGAUGAGG
12293





5064
UCAUCUCUC AGGCUGUG
2882
CACAGCCU CUGAUGAGGCCGUUAGGCCGAA AGAGAUGA
12294





5076
CUGUGCCUU AAUUCAGA
2883
UCUGAAUU CUGAUGAGGCCGUUAGGCCGAA AGGCACAG
12295





5077
UGUGCCUUA AUUCAGAA
2884
UUCUGAAU CUGAUGAGGCCGUUAGGCCGAA AAGGCACA
12296





5080
GCCUUAAUU CAGAACAC
2885
GUGUUCUG CUGAUGAGGCCGUUAGGCCGAA AUUAAGGC
12297





5081
CCUUAAUUC AGAACACC
2886
GGUGUUCU CUGAUGAGGCCGUUAGGCCGAA AAUUAAGG
12298





5105
AGGAACGUC GGCAGAGG
2887
CCUCUGCC CUGAUGAGGCCGUUAGGCCGAA ACGUUCCU
12299





5116
CAGAGGCUC CUGACGGG
2888
CCCGUCAG CUGAUGAGGCCGUUAGGCCGAA AGCCUCUG
12300





5135
CGAAGAAUU GUGAGAAC
2889
GUUCUCAC CUGAUGAGGCCGUUAGGCCGAA AUUCUUCG
12301





5156
CAGAAACUC AGGGUUUC
2890
GAAACCCU CUGAUGAGGCCGUUAGGCCGAA AGUUUCUG
12302





5162
CUCAGGGUU UCUGCUGG
2891
CCAGCAGA CUGAUGAGGCCGUUAGGCCGAA ACCCUGAG
12303





5163
UCAGGGUUU CUGCUGGG
2892
CCCAGCAG CUGAUGAGGCCGUUAGGCCGAA AACCCUGA
12304





5164
CAGGGUUUC UGCUGGGU
2893
ACCCAGCA CUGAUGAGGCCGUUAGGCCGAA AAACCCUG
12305





5203
UGGCAGGUC UGAGGGUU
2894
AACCCUCA CUGAUGAGGCCGUUAGGCCGAA ACCUGCCA
12306





5211
CUGAGGGUU CUCUGUCA
2895
UGACAGAG CUGAUGAGGCCGUUAGGCCGAA ACCCUCAG
12307





5212
UGAGGGUUC UCUGUCAA
2896
UUGACAGA CUGAUGAGGCCGUUAGGCCGAA AACCCUCA
12308





5214
AGGGUUCUC UGUCAAGU
2897
ACUUGACA CUGAUGAGGCCGUUAGGCCGAA AGAACCCU
12309





5218
UUCUCUGUC AAGUGGCG
2898
CGCCACUU CUGAUGAGGCCGUUAGGCCGAA ACAGAGAA
12310





5229
GUGGCGGUA AAGGCUCA
2899
UGAGCCUU CUGAUGAGGCCGUUAGGCCGAA ACCGCCAC
12311





5236
UAAAGGCUC AGGCUGGU
2900
ACCAGCCU CUGAUGAGGCCGUUAGGCCGAA AGCCUUUA
12312





5247
GCUGGUGUU CUUCCUCU
2901
AGAGGAAG CUGAUGAGGCCGUUAGGCCGAA ACACCAGC
12313





5248
CUGGUGUUC UUCCUCUA
2902
UAGAGGAA CUGAUGAGGCCGUUAGGCCGAA AACACCAG
12314





5250
GGUGUUCUU CCUCUAUC
2903
GAUAGAGG CUGAUGAGGCCGUUAGGCCGAA AGAACACC
12315





5251
GUGUUCUUC CUCUAUCU
2904
AGAUAGAG CUGAUGAGGCCGUUAGGCCGAA AAGAACAC
12316





5254
UUCUUCCUC UAUCUCCA
2905
UGGAGAUA CUGAUGAGGCCGUUAGGCCGAA AGGAAGAA
12317





5256
CUUCCUCUA UCUCCACU
2906
AGUGGAGA CUGAUGAGGCCGUUAGGCCGAA AGAGGAAG
12318





5258
UCCUCUAUC UCCACUCC
2907
GGAGUGGA CUGAUGAGGCCGUUAGGCCGAA AUAGAGGA
12319





5260
CUCUAUCUC CACUCCUG
2908
CAGGAGUG CUGAUGAGGCCGUUAGGCCGAA AGAUAGAG
12320





5265
UCUCCACUC CUGUCAGG
2909
CCUGACAG CUGAUGAGGCCGUUAGGCCGAA AGUGGAGA
12321





5270
ACUCCUGUC AGGCCCCC
2910
GGGGGCCU CUGAUGAGGCCGUUAGGCCGAA ACAGGAGU
12322





5283
CCCCAAGUC CUCAGUAU
2911
AUACUGAG CUGAUGAGGCCGUUAGGCCGAA ACUUGGGG
12323





5286
CAAGUCCUC AGUAUUUU
2912
AAAAUACU CUGAUGAGGCCGUUAGGCCGAA AGGACUUG
12324





5290
UCCUCAGUA UUUUAGCU
2913
AGCUAAAA CUGAUGAGGCCGUUAGGCCGAA ACUGAGGA
12325





5292
CUCAGUAUU UUAGCUUU
2914
AAAGCUAA CUGAUGAGGCCGUUAGGCCGAA AUACUGAG
12326





5293
UCAGUAUUU UAGCUUUG
2915
CAAAGCUA CUGAUGAGGCCGUUAGGCCGAA AAUACUGA
12327





5294
CAGUAUUUU AGCUUUGU
2916
ACAAAGCU CUGAUGAGGCCGUUAGGCCGAA AAAUACUG
12328





5295
AGUAUUUUA GCUUUGUG
2917
CACAAAGC CUGAUGAGGCCGUUAGGCCGAA AAAAUACU
12329





5299
UUUUAGCUU UGUGGCUU
2918
AAGCCACA CUGAUGAGGCCGUUAGGCCGAA AGCUAAAA
12330





5300
UUUAGCUUU GUGGCUUC
2919
GAAGCCAC CUGAUGAGGCCGUUAGGCCGAA AAGCUAAA
12331





5307
UUGUGGCUU CCUGAUGG
2920
CCAUCAGG CUGAUGAGGCCGUUAGGCCGAA AGCCACAA
12332





5308
UGUGGCUUC CUGAUGGC
2921
GCCAUCAG CUGAUGAGGCCGUUAGGCCGAA AAGCCACA
12333





5325
AGAAAAAUC UUAAUUGG
2922
CCAAUUAA CUGAUGAGGCCGUUAGGCCGAA AUUUUUCU
12334





5327
AAAAAUCUU AAUUGGUU
2923
AACCAAUU CUGAUGAGGCCGUUAGGCCGAA AGAUUUUU
12335





5328
AAAAUCUUA AUUGGUUG
2924
CAACCAAU CUGAUGAGGCCGUUAGGCCGAA AAGAUUUU
12336





5331
AUCUUAAUU GGUUGGUU
2925
AACCAACC CUGAUGAGGCCGUUAGGCCGAA AUUAAGAU
12337





5335
UAAUUGGUU GGUUUGCU
2926
AGCAAACC CUGAUGAGGCCGUUAGGCCGAA ACCAAUUA
12338





5339
UGGUUGGUU UGCUCUCC
2927
GGAGAGCA CUGAUGAGGCCGUUAGGCCGAA ACCAACCA
12339





5340
GGUUGGUUU GCUCUCCA
2928
UGGAGAGC CUGAUGAGGCCGUUAGGCCGAA AACCAACC
12340





5344
GGUUUGCUC UCCAGAUA
2929
UAUCUGGA CUGAUGAGGCCGUUAGGCCGAA AGCAAACC
12341





5346
UUUGCUCUC CAGAUAAU
2930
AUUAUCUG CUGAUGAGGCCGUUAGGCCGAA AGAGCAAA
12342





5352
CUCCAGAUA AUCACUAG
2931
CUAGUGAU CUGAUGAGGCCGUUAGGCCGAA AUCUGGAG
12343





5355
CAGAUAAUC ACUAGCCA
2932
UGGCUAGU CUGAUGAGGCCGUUAGGCCGAA AUUAUCUG
12344





5359
UAAUCACUA GCCAGAUU
2933
AAUCUGGC CUGAUGAGGCCGUUAGGCCGAA AGUGAUUA
12345





5367
AGCCAGAUU UCGAAAUU
2934
AAUUUCGA CUGAUGAGGCCGUUAGGCCGAA AUCUGGCU
12346





5368
GCCAGAUUU CGAAAUUA
2935
UAAUUUCG CUGAUGAGGCCGUUAGGCCGAA AAUCUGGC
12347





5369
CCAGAUUUC GAAAUUAC
2936
GUAAUUUC CUGAUGAGGCCGUUAGGCCGAA AAAUCUGG
12348





5375
UUCGAAAUU ACUUUUUA
2937
UAAAAAGU CUGAUGAGGCCGUUAGGCCGAA AUUUCGAA
12349





5376
UCGAAAUUA CUUUUUAG
2938
CUAAAAAG CUGAUGAGGCCGUUAGGCCGAA AAUUUCGA
12350





5379
AAAUUACUU UUUAGCCG
2939
CGGCUAAA CUGAUGAGGCCGUUAGGCCGAA AGUAAUUU
12351





5380
AAUUACUUU UUAGCCGA
2940
UCGGCUAA CUGAUGAGGCCGUUAGGCCGAA AAGUAAUU
12352





5381
AUUACUUUU UAGCCGAG
2941
CUCGGCUA CUGAUGAGGCCGUUAGGCCGAA AAAGUAAU
12353





5382
UUACUUUUU AGCCGAGG
2942
CCUCGGCU CUGAUGAGGCCGUUAGGCCGAA AAAAGUAA
12354





5383
UACUUUUUA GCCGAGGU
2943
ACCUCGGC CUGAUGAGGCCGUUAGGCCGAA AAAAAGUA
12355





5392
GCCGAGGUU AUGAUAAC
2944
GUUAUCAU CUGAUGAGGCCGUUAGGCCGAA ACCUCGGC
12356





5393
CCGAGGUUA UGAUAACA
2945
UGUUAUCA CUGAUGAGGCCGUUAGGCCGAA AACCUCGG
12357





5398
GUUAUGAUA ACAUCUAC
2946
GUAGAUGU CUGAUGAGGCCGUUAGGCCGAA AUCAUAAC
12358





5403
GAUAACAUC UACUGUAU
2947
AUACAGUA CUGAUGAGGCCGUUAGGCCGAA AUGUUAUC
12359





5405
UAACAUCUA CUGUAUCC
2948
GGAUACAG CUGAUGAGGCCGUUAGGCCGAA AGAUGUUA
12360





5410
UCUACUGUA UCCUUUAG
2949
CUAAAGGA CUGAUGAGGCCGUUAGGCCGAA ACAGUAGA
12361





5412
UACUGUAUC CUUUAGAA
2950
UUCUAAAG CUGAUGAGGCCGUUAGGCCGAA AUACAGUA
12362





5415
UGUAUCCUU UAGAAUUU
2951
AAAUUCUA CUGAUGAGGCCGUUAGGCCGAA AGGAUACA
12363





5416
GUAUCCUUU AGAAUUUU
2952
AAAAUUCU CUGAUGAGGCCGUUAGGCCGAA AAGGAUAC
12364





5417
UAUCCUUUA GAAUUUUA
2953
UAAAAUUC CUGAUGAGGCCGUUAGGCCGAA AAAGGAUA
12365





5422
UUUAGAAUU UUAACCUA
2954
UAGGUUAA CUGAUGAGGCCGUUAGGCCGAA AUUCUAAA
12366





5423
UUAGAAUUU UAACCUAU
2955
AUAGGUUA CUGAUGAGGCCGUUAGGCCGAA AAUUCUAA
12367





5424
UAGAAUUUU AACCUAUA
2956
UAUAGGUU CUGAUGAGGCCGUUAGGCCGAA AAAUUCUA
12368





5425
AGAAUUUUA ACCUAUAA
2957
UUAUAGGU CUGAUGAGGCCGUUAGGCCGAA AAAAUUCU
12369





5430
UUUAACCUA UAAAACUA
2958
UAGUUUUA CUGAUGAGGCCGUUAGGCCGAA AGGUUAAA
12370





5432
UAACCUAUA AAACUAUG
2959
CAUAGUUU CUGAUGAGGCCGUUAGGCCGAA AUAGGUUA
12371





5438
AUAAAACUA UGUCUACU
2960
AGUAGACA CUGAUGAGGCCGUUAGGCCGAA AGUUUUAU
12372





5442
AACUAUGUC UACUGGUU
2961
AACCAGUA CUGAUGAGGCCGUUAGGCCGAA ACAUAGUU
12373





5444
CUAUGUCUA CUGGUUUC
2962
GAAACCAG CUGAUGACGCCGUUAGGCCGAA AGACAUAG
12374





5450
CUACUGGUU UCUGCCUG
2963
CAGGCAGA CUGAUGAGGCCGUUAGGCCGAA ACCAGUAG
12375





5451
UACUGGUUU CUGCCUGU
2964
ACAGGCAG CUGAUGAGGCCGUUAGGCCGAA AACCAGUA
12376





5452
ACUGGUUUC UGCCUGUG
2965
CACAGGCA CUGAUGAGGCCGUUAGGCCGAA AAACCAGU
12377






Where “X” represents stem II region of a HH ribozyme (Hertel et al., 1992 Nucleic Acids Res. 20 3252).




The length of stem II may be 2 base-pairs.




Underlined region can be any X sequence or linker, as described herein.








[0346]

10






TABLE VII










Mouseflk-1 VEGF Receptor-Hairpin Ribozyme and Substrate Sequences















Seq

Seq





ID

ID


Pos
Substrate
No
HP Ribozyme Sequences
No















74
GGGCCCA GAC UGUGUCCC
2966
GGGACACA AGAA GGGCCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12378






88
UCCCGCA GCC GGGAUAAC
2967
GUUAUCCC AGAA GCGGGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12379





105
CCUGGCU GAC CCGAUUCC
2968
GGAAUCGG AGAA GCCAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12380





110
GUGACCC GAU UCCGCGGA
2969
UCCGCGGA AGAA GGUCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12381





125
GGACACC GCU GACAGCCG
2970
GGGCUGUC AGAA GUGUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12382





132
GCUGACA GCC GCGGCUGG
2971
CCAGCCGC AGAA GUCAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12383





138
AGCCGCG GCU GGAGCCAG
2972
CUGGCUCC AGAA GCGGCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12384





175
CUCCCCG GUC UUGCGCUG
2973
CAGCGCAA AGAA GGGGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12385





199
CCAUACC GCC UCUGUGAC
2974
GUCACAGA AGAA GUAUGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12386





309
GCUAGCU GUC GCUCUGUG
2975
CACAGAGC AGAA GCUAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12387





342
CCGAGCC CCC UCUGUGGG
2976
CCCACAGA AGAA GCUCGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12388





434
CCCUUCA GAU UACUUGCA
2977
UGCAAGUA AGAA GAAGGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12389





630
GUCCACU GUU UAUGUCUA
2978
UAGACAUA AGAA GUGGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12390





655
GAUUACA GAU CACCAUUC
2979
GAAUGGUG AGAA GUAAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12391





739
AUCCCCU GCC GAGGGUCG
2980
GGACCCUC AGAA GGGGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12392





807
UGUUCCG GAU GGAAACAG
2981
CUGUUUCC AGAA GGAACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12393





920
GCUAUCA GUC UAUCAUGU
2982
ACAUGAUA AGAA GAUAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12394





1002
GCUAUCU GCC GGAGAAAA
2983
UUUUCUCC AGAA GAUAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12395





1229
GUGGACG GAU GAUCAAGA
2984
UCUUGAUC AGAA GUCCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12396





1365
UUACCCA GCU CCUGAUAU
2985
AUAUCAGG AGAA GGGUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12397





1556
CACCCCA GAU COGUGAGA
2986
UCUCACCG AGAA GGGGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12398





1629
AUCCACA GUC UACGCCAA
2987
UUGGCGUA AGAA GUGCAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12399





1687
GAAGCCU GCU CCUACAGA
2988
UCUGUAGG AGAA GGCUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12400





1696
UCCUACA GAC CCGGCCAA
2989
UUGGCCGG AGAA GUAGGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12401





1795
AUGCCCU GAU UGAAGGAA
2990
UUCCUUCA AGAA GGGCAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12402





1950
GCAACCU GCU GCCCAGCC
2991
GGCUGGGC AGAA GGUUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12403





1953
ACCUGCU GCC CAGCCAAC
2992
GUUGGCUG AGAA GCAGGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12404





1985
UGUCCCU GUU GUCCACUG
2993
CAGUCCAC AGAA GGGACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12405





2055
AACAUCG GUC CACAUGGG
2994
CCCAUGUG AGAA GAUGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12406





2082
CACACCA GUU UGCAAGAA
2995
UUCUUGCA AGAA GGUGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11606





2208
UUGCUCU GCU CAAGAUAA
2996
UUAUCUUG AGAA GAGCAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12407





2252
UCAAACA GCU CAUCAUCC
2997
GGAUGAUG AGAA GUUUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12408





2444
GGAACCU GAC UAUCCGCA
2998
UGCGGAUA AGAA GGUUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12409





2639
UCCUACG GAC CGUUAAGC
2999
GCUUAACG AGAA GUAGGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12410





2703
GGAUCCA GAU GAAUUGCC
3000
GGCAAUUC AGAA GGAUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12411





2777
GGGACCG GCU GAAACUAG
3001
CUAGUUUC AGAA GGUCCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12412





2832
UGAGGCA GAC GCUUUUGG
3002
CCAAAAGC AGAA GCCUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12413





3199
UCUGOCA GCU CAGGCUUU
3003
AAAGCCUG AGAA GGCAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12414





3278
ACUUCCU GAC CUUGGAGC
2199
GCUCCAAG AGAA GGAAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11618





3304
UGUUACA GCU UCCAAGUG
2200
GACUUGGA AGAA GUAACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11619





3421
GACUUCG GCU UGGCCCGG
3004
CCGGGCCA AGAA GAAGUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12415





3450
AGACCCG GAU UAUGUCAG
3005
CUGACAUA AGAA GGGUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12416





3475
GAUGCCC GAC UCCCUUUG
3006
CAAAGGGA AGAA GGCAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12417





3663
GGCUCCU GAC UACACUAC
3007
GUAGUGUA AGAA GGAGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12418





3689
UGUACCA GAC CAUGCUGG
2203
CCAGCAUG AGAA GGUACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11622





3703
CUGGACU GCU GGCAUGAG
3008
CUCAUGCC AGAA GUCCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12419





3860
UCUCCCU GCC UACCUCAC
3009
GUGAGGUA AGAA GGGAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12420





3873
CUCACCU GUU UCCUGUAU
2205
AUACAGGA AGAA GGUGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11625





4038
GAUCCCA GAU GACAGCCA
3010
UGGCUGUC AGAA GGGAUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12421





4181
CCAACCA GAC CAGUGGCU
3011
AGCCACUG AGAA GGUUGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12422





4196
GCUACCA GUC UGGGUAUC
3012
GAUACCCA AGAA GGUAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12423





4212
UCACUCA GAU GACACAGA
3013
UCUGUGUC AGAA GAGUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
11630





4278
UGCUGCA GUC CACGCUGA
3014
UCAGCGUG AGAA GCAGCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12424





4287
UCACGCU GAC UCAGGGAC
3015
GUCCCUGA AGAA GCGUGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12425





4307
CACUGCA GCU CACCUCCU
3015
AGGAGGUG AGAA GCAGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12426





4318
ACCUCCU GUU UAAAUGGA
3017
UCCAUUUA AGAA GGAGGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12427





4338
UGGUCCU GUC CCGGCUCC
3018
GGAGCCGG AGAA GGACCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12428





4344
UGUCCCG GCU CCGCCCCC
3019
GGGGGCGG AGAA GGGACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12429





4349
CGGCUCC GCC CCCAACUC
3020
GAGUUGGG AGAA GAGCCG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12430





4383
AGGUGCU GCU UAGAUUUU
3021
AAAAUCUA AGAA GCACCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12431





4462
GACCUCA GAC UGCAAGGA
3022
UCCUUGCA AGAA GAGGUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12432





4574
GUGCCCU GCU GUGGUCUC
3023
GAGACCAC AGAA GGGCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12433





4626
GGACUCU GUC CUCCAAGA
3024
UCUUGGAG AGAA GAGUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12434





4723
CGAGUCU GUC UACCUUGG
3025
CCAAGGUA AGAA GACUCG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12435





4823
GAGAGCG GUU GGAGCCUG
3026
CAGGCUCC AGAA GCUCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12436





4836
GCCUGCA GAU GCAUUGUG
3027
CACAAUGC AGAA GCAGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12437





4895
AAAGGCG CCC GGCAGGGU
3028
ACCCUGCC AGAA CCCUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12438





4938
CUUCACA GUC GGGUUACA
3029
UGUAACCC AGAA GUGAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12439





4996
CCUUCCG GAC UCUUACGU
3030
ACGUAAGA AGAA GGAAGG ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
12440





5042
UGAUCCA GCU UGCUCCUU
3031
AAGGAGCA AGAA GCAUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12441





5118
GGCUCCU GAC GGGGCCGA
3032
UCGGCCCC AGAA GGAGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12442





5165
GGUUUCU GCU GUGUGGAG
3033
CUCCACCC AGAA GAAACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12443





5310
GCUUCCU GAU GGCAGAAA
3034
UUUCUGCC AGAA GGAAGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12444





5363
CUAGCCA GAU UUCGAAAU
3035
AUUUCGAA AGAA GGCUAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12445





5453
GGUUUCU CCC UGUGUGCU
3035
AGCACACA AGAA GAAACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
12446










[0347]

11






TABLE VIII










Mouse flt-1 VEGF Receptor-Hammerhead Ribozyme and Substrate Sequence















Seq

Seq





ID

ID


Pos
Substrate
No
HH Ribozyme Sequence
No















17
GGCCGCGUC UUGCUCAC
3037
GUGAGCAA CUGAUGAGGCCGUUAGGCCGAA ACGCGGCC
12447






19
CCGCGUCUU GCUCACCA
3038
UGGUGAGC CUGAUGAGGCCGUUAGGCCGAA AGACGCGG
12448





23
GUCUUGCUC ACCAUGGU
3039
ACCAUGGU CUGAUGAGGCCGUUAGGCCGAA AGCAAGAC
12449





32
ACCAUGGUC AGCUGCUG
3040
CAGCAGCU CUGAUGAGGCCGUUAGGCCGAA ACCAUGGU
12450





53
ACCGCGGUC UUGCCUUA
3041
UAAGGCAA CUGAUGAGGCCGUUAGGCCGAA ACCGCGGU
12451





55
CGCGGUCUU GCCUUACG
3042
CGUAAGGC CUGAUGAGGCCGUUAGGCCGAA AGACCGCG
12452





60
UCUUGCCUU ACGCGCUG
3043
CAGCGCGU CUGAUGAGGCCGUUAGGCCGAA AGGCAAGA
12453





61
CUUGCCUUA CGCGCUGC
3044
GCAGCGCG CUGAUGAGGCCGUUAGGCCGAA AAGGCAAG
12454





71
GCGCUGCUC GGGUGUCU
3045
AGACACCC CUGAUGAGGCCGUUAGGCCGAA AGCAGCGC
12455





78
UCGGGUGUC UGCUUCUC
3048
GAGAAGCA CUGAUGAGGCCGUUAGGCCGAA ACACCCGA
12456





83
UGUCUGCUU CUCACAGG
25
CCUGUGAG CUGAUGAGGCCGUUAGGCCGAA AGCAGACA
9444





84
GUCUGCUUC UCACAGGA
26
UCCUGUGA CUGAUGAGGCCGUUAGGCCGAA AAGCAGAC
9445





86
CUGCUUCUC ACAGGAUA
3047
UAUCCUGU CUGAUGAGGCCGUUAGGCCGAA AGAAGCAG
12457





94
CACAGGAUA UGGCUCAG
3048
CUGAGCCA CUGAUGAGGCCGUUAGGCCGAA AUCCUGUG
12458





100
AUAUGGCUC AGGGUCGA
3049
UCGACCCU CUGAUGAGGCCGUUAGGCCGAA AGCCAUAU
12459





106
CUCAGGGUC GAAGUUAA
3050
UUAACUUC CUGAUGAGGCCGUUAGGCCGAA ACCCUGAG
12460





112
GUCGAAGUU AAAAGUGC
3051
GCACUUUU CUGAUGAGGCCGUUAGGCCGAA ACUUCGAC
12461





113
UCGAAGUUA AAAGUGCC
3052
GGCACUUU CUGAUGAGGCCGUUAGGCCGAA AACUUCGA
12462





132
AACUGAGUU UAAAAGGC
37
GCCUUUUA CUGAUGAGGCCGUUAGGCCGAA ACUCAGUU
9456





133
ACUGAGUUU AAAAGGCA
38
UGCCUUUU CUGAUGAGGCCGUUAGGCCGAA AACUCAGU
9457





134
CUGAGUUUA AAAGGCAC
39
GUGCCUUU CUGAUGAGGCCGUUAGGCCGAA AAACUCAG
9458





152
CAGCAUGUC AUGCAAGC
3053
GCUUGCAU CUGAUGAGGCCGUUAGGCCGAA ACAUGCUG
12463





171
GCCAGACUC UCUUUCUC
3054
GAGAAAGA CUGAUGAGGCCGUUAGGCCGAA AGUCUGGC
12464





173
CAGACUCUC UUUCUCAA
3055
UUGAGAAA CUGAUGAGGCCGUUAGGCCGAA AGAGUCUG
12465





175
GACUCUCUU UCUCAAGU
3056
ACUUGAGA CUGAUGAGGCCGUUAGGCCGAA AGAGAGUC
12466





176
ACUCUCUUU CUCAAGUG
3057
CACUUGAG CUGAUGAGGCCGUUAGGCCGAA AAGAGAGU
12467





177
CUCUCUUUC UCAAGUGC
3058
GCACUUGA CUGAUGAGGCCGUUAGGCCGAA AAAGAGAG
12468





179
CUCUUUCUC AAGUGCAG
3059
CUGCACUU CUGAUGAGGCCGUUAGGCCGAA AGAAAGAG
12469





205
AGCCCACUC AUGGUCUC
3060
GAGACCAU CUGAUGAGGCCGUUAGGCCGAA AGUGGGCU
12470





211
CUCAUGGUC UCUGCCCA
3061
UGGGCAGA CUGAUGAGGCCGUUAGGCCGAA ACCAUGAG
12471





213
CAUGGUCUC UGCCCACG
3062
CGUGGGCA CUGAUGAGGCCGUUAGGCCGAA AGACCAUG
12472





254
CUGAGCAUC ACUCCCCC
3063
GGGGGAGU CUGAUGAGGCCGUUAGGCCGAA AUGCUCAG
12473





258
GCAUCACUC CCCCAUCG
3064
CGAUGGGG CUGAUGAGGCCGUUAGGCCGAA AGUGAUGC
12474





265
UCCCCCAUC GGCCUGUG
3065
CACAGGCC CUGAUGAGGCCGUUAGGCCGAA AUGGGGGA
12475





282
GGAGGGAUA ACAGGCAA
3066
UUGCCUGU CUGAUGAGGCCGUUAGGCCGAA AUCCCUCC
12476





292
CAGGCAAUU CUGCAGCA
3067
UGCUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUGCCUG
12477





293
AGGCAAUUC UGCAGCAC
3068
GUGCUGCA CUGAUGAGGCCGUUAGGCCGAA AAUUGCCU
12478





304
CAGCACCUU GACCUUGG
3069
CCAAGGUC CUGAUGAGGCCGUUAGGCCGAA AGGUGCUG
12479





310
CUUGACCUU GGACACGG
3070
CCGUGUCC CUGAUGAGGCCGUUAGGCCGAA AGGUCAAG
12480





341
ACGGGCCUC UACACCUG
3071
CAGGUGUA CUGAUGAGGCCGUUAGGCCGAA AGGCCCGU
12481





343
GGGCCUCUA CACCUGUA
3072
UACAGGUG CUGAUGAGGCCGUUAGGCCGAA AGAGGCCC
12482





351
ACACCUGUA GAUACCUC
3073
GAGGUAUC CUGAUGAGGCCGUUAGGCCGAA ACAGGUGU
12483





355
CUGUAGAUA CCUCCCUA
3074
UAGGGAGG CUGAUGAGGCCGUUAGGCCGAA AUCUACAG
12484





359
AGAUACCUC CCUACAUC
3075
GAUGUAGG CUGAUGAGGCCGUUAGGCCGAA AGGUAUCU
12485





363
ACCUCCCUA CAUCUACU
3076
AGUAGAUG CUGAUGAGGCCGUUAGGCCGAA AGGGAGGU
12486





367
CCCUACAUC UACUUCGA
3077
UCGAAGUA CUGAUGAGGCCGUUAGGCCGAA AUGUAGGG
12487





369
CUACAUCUA CUUCGAAG
3078
CUUCGAAG CUGAUGAGGCCGUUAGGCCGAA AGAUGUAG
12488





372
CAUCUACUU CGAAGAAA
3079
UUUCUUCG CUGAUGAGGCCGUUAGGCCGAA AGUAGAUG
12489





373
AUCUACUUC GAAGAAAA
3080
UUUUCUUC CUGAUGAGGCCGUUAGGCCGAA AAGUAGAU
12490





394
AGCGGAAUC UUCAAUCU
3081
AGAUUGAA CUGAUGAGGCCGUUAGGCCGAA AUUCCGCU
12491





396
CGGAAUCUU CAAUCUAC
3082
GUAGAUUG CUGAUGAGGCCGUUAGGCCGAA AGAUUCCG
12492





397
GGAAUCUUC AAUCUACA
3083
UGUAGAUU CUGAUGAGGCCGUUAGGCCGAA AAGAUUCC
12493





401
UCUUCAAUC UACAUAUU
3084
AAUAUGUA CUGAUGAGGCCGUUAGGCCGAA AUUGAAGA
12494





403
AUCAAUCUA CAUAUUUG
3085
CAAAUAUG CUGAUGAGGCCGUUAGGCCGAA AGAUUGAA
12495





407
AUCUACAUA UUUGUUAG
3086
CUAACAAA CUGAUGAGGCCGUUAGGCCGAA AUGUAGAU
12496





409
CUACAUAUU UGUUAGUG
3087
CACUAACA CUGAUGAGGCCGUUAGGCCGAA AUAUGUAG
12497





410
UACAUAUUU GUUAGUGA
3088
UCACUAAC CUGAUGAGGCCGUUAGGCCGAA AAUAUGUA
12498





413
AUAUUUGUU AGUGAUGC
3089
GCAUCACU CUGAUGAGGCCGUUAGGCCGAA ACAAAUAU
12499





414
UAUUUGUUA GUGAUGCA
3090
UGCAUCAC CUGAUGAGGCCGUUAGGCCGAA AACAAAUA
12500





429
CAGGGAGUC CUUUCAUA
3091
UAUGAAAG CUGAUGAGGCCGUUAGGCCGAA ACUCCCUG
12501





432
GGAGUCCUU UCAUAGAG
3092
CUCUAUGA CUGAUGAGGCCGUUAGGCCGAA AGGACUCC
12502





433
GAGUCCUUU CAUAGAGA
3093
UCUCUAUG CUGAUGAGGCCGUUAGGCCGAA AAGGACUC
12503





434
AGUCCUUUC AUAGAGAU
3094
AUCUCUAU CUGAUGAGGCCGUUAGGCCGAA AAAGGACU
12504





437
CCUUUCAUA GAGAUGCA
3095
UGCAUCUC CUGAUGAGGCCGUUAGGCCGAA AUGAAAGG
12505





455
ACUGACAUA CCCAAACU
3096
AGUUUGGG CUGAUGAGGCCGUUAGGCCGAA AUGUCAGU
12506





464
CCCAAACUU GUGCACAU
3097
AUGUGCAC CUGAUGAGGCCGUUAGGCCGAA AGUUUGGG
12507





491
AGACAGCUC AUCAUCCC
3098
GGGAUGAU CUGAUGAGGCCGUUAGGCCGAA AGCUGUCU
12508





494
CAGCUCAUC AUCCCCUG
3099
CAGGGGAU CUGAUGAGGCCGUUAGGCCGAA AUGAGCUG
12509





497
CUCAUCAUC CCCUGCCG
3100
CGGCAGGG CUGAUGAGGCCGUUAGGCCGAA AUGAUGAG
12510





514
GGUGACGUC ACCCAACG
3101
CGUUGGGU CUGAUGAGGCCGUUAGGCCGAA ACGUCACC
12511





524
CCCAACGUC ACAGUCAC
3102
GUGACUGU CUGAUGAGGCCGUUAGGCCGAA ACGUUGGG
12512





530
GUCACAGUC ACCCUAAA
3103
UUUAGGGU CUGAUGAGGCCGUUAGGCCGAA ACUGUGAC
12513





536
GUCACCCUA AAAAAGUU
3104
AACUUUUU CUGAUGAGGCCGUUAGGCCGAA AGGGUGAC
12514





544
AAAAAAGUU UCCAUUUG
3105
CAAAUGGA CUGAUGAGGCCGUUAGGCCGAA ACUUUUUU
12515





545
AAAAAGUUU CCAUUUGA
3106
UCAAAUGG CUGAUGAGGCCGUUAGGCCGAA AACUUUUU
12516





546
AAAAGUUUC CAUUUGAU
3107
AUCAAAUG CUGAUGAGGCCGUUAGGCCGAA AAACUUUU
12517





550
GUUUCCAUU UGAUACUC
3108
GAGUAUCA CUGAUGAGGCCGUUAGGCCGAA AUGGAAAC
12518





551
UUUCCAUUU GAUACUCU
3109
AGAGUAUC CUGAUGAGGCCGUUAGGCCGAA AAUGGAAA
12519





555
CAUUUGAUA CUCUUACC
3110
GGUAAGAG CUGAUGAGGCCGUUAGGCCGAA AUCAAAUG
12520





558
UUGAUACUC UUACCCCU
3111
AGGGGUAA CUGAUGAGGCCGUUAGGCCGAA AGUAUCAA
12521





560
GAUACUCUU ACCCCUGA
3112
UCAGGGGU CUGAUGAGGCCGUUAGGCCGAA AGAGUAUC
12522





561
AUACUCUUA CCCCUGAU
3113
AUCAGGGG CUGAUGAGGCCGUUAGGCCGAA AAGAGUAU
12523





581
CAAAGAAUA ACAUGGGA
3114
UCCCAUGU CUGAUGAGGCCGUUAGGCCGAA AUUCUUUG
12524





594
GGGACAGUA GGAGAGGC
3115
GCCUCUCC CUGAUGAGGCCGUUAGGCCGAA ACUGUCCC
12525





604
GAGAGGCUU UAUAAUAG
3116
CUAUUAUA CUGAUGAGGCCGUUAGGCCGAA AGCCUCUC
12526





605
AGAGGCUUU AUAAUAGC
3117
GCUAUUAU CUGAUGAGGCCGUUAGGCCGAA AAGCCUCU
12527





606
GAGGCUUUA UAAUAGCA
3118
UGCUAUUA CUGAUGAGGCCGUUAGGCCGAA AAAGCCUC
12528





608
GGCUUUAUA AUAGCAAA
3119
UUUGCUAU CUGAUGAGGCCGUUAGGCCGAA AUAAAGCC
12529





611
UUUAUAAUA GCAAAUGC
3120
GCAUUUGC CUGAUGAGGCCGUUAGGCCGAA AUUAUAAA
12530





625
UGCAACGUA CAAAGAGA
3121
UCUCUUUG CUGAUGAGGCCGUUAGGCCGAA ACGUUGCA
12531





635
AAAGAGAUA GGACUGCU
3122
AGCAGUCC CUGAUGAGGCCGUUAGGCCGAA AUCUCUUU
12532





662
GCCACCGUC AACGGGCA
3123
UGCCCGUU CUGAUGAGGCCGUUAGGCCGAA ACGCUGGC
12533





676
GCACCUGUA CCAGACAA
3124
UUGUCUGG CUGAUGAGGCCGUUAGGCCGAA ACAGGUGC
12534





688
GACAAACUA UCUGACCC
3125
GGGUCAGA CUGAUGAGGCCGUUAGGCCGAA AGUUUGUC
12535





690
CAAACUAUC UGACCCAU
3126
AUGGGUCA CUGAUGAGGCCGUUAGGCCGAA AUAGUUUG
12536





699
UGACCCAUC GGCAGACC
3127
GGUCUGCC CUGAUGAGGCCGUUAGGCCGAA AUGGGUCA
12537





711
AGACCAAUA CAAUCCUA
3128
UAGGAUUG CUGAUGAGGCCGUUAGGCCGAA AUUGGUCU
12538





716
AAUACAAUC CUAGAUGU
3129
ACAUCUAG CUGAUGAGGCCGUUAGGCCGAA AUUGUAUU
12539





719
ACAAUCCUA GAUGUCCA
3130
UGGACAUC CUGAUGAGGCCGUUAGGCCGAA AGGAUUGU
12540





725
CUAGAUGUC CAAAUACG
3131
CGUAUUUG CUGAUGAGGCCGUUAGGCCGAA ACAUCUAG
12541





731
GUCCAAAUA CGCCCGCC
3132
GGCGGGCG CUGAUGAGGCCGUUAGGCCGAA AUUUGGAC
12542





758
AGACUGCUC CACGGGCA
3133
UGCCCGUG CUGAUGAGGCCGUUAGGCCGAA AGCAGUCU
12543





771
GGCAGACUC UUGUCCUC
3134
GAGGACAA CUGAUGAGGCCGUUAGGCCGAA AGUCUGCC
12544





773
CAGACUCUU GUCCUCAA
3135
UUGAGGAC CUGAUGAGGCCGUUAGGCCGAA AGAGUCUG
12545





776
ACUCUUGUC CUCAACUG
3136
CAGUUGAG CUGAUGAGGCCGUUAGGCCGAA ACAAGAGU
12546





779
CUUGUCCUC AACUGCAC
3137
GUGCAGUU CUGAUGAGGCCGUUAGGCCGAA AGGACAAG
12547





803
ACGGAGCUC AAUACGAG
3138
CUCGUAUU CUGAUGAGGCCGUUAGGCCGAA AGCUCCGU
12548





807
AGCUCAAUA CGAGGGUG
3139
CACCCUCG CUGAUGAGGCCGUUAGGCCGAA AUUGAGCU
12549





831
GCUGGAAUU ACCCUGGU
3140
ACCAGGGU CUGAUGAGGCCGUUAGGCCGAA AUUCCAGC
12550





832
CUGGAAUUA CCCUGGUA
3141
UACCAGGG CUGAUGAGGCCGUUAGGCCGAA AAUUCCAG
12551





840
ACCCUGGUA AAGCAACU
3142
AGUUGCUU CUGAUGAGGCCGUUAGGCCGAA ACCAGGGU
12552





849
AAGCAACUA AGAGAUCA
3143
UGCUCUCU CUGAUGAGGCCGUUAGGCCGAA AGUUGCUU
12553





859
GAGAGCAUC UAUAAGGC
3144
GCCUUAUA CUGAUGAGGCCGUUAGGCCGAA AUGCUCUC
12554





861
GAGCAUCUA UAAGGCAG
3145
CUGCCUUA CUGAUGAGGCCGUUAGGCCGAA AGAUGCUC
12555





863
GCAUCUAUA AGGCAGCG
3146
CGCUGCCU CUGAUGAGGCCGUUAGGCCGAA AUAGAUGC
12556





875
CAGCGGAUU GACCGGAG
3147
CUCCGGUC CUGAUGAGGCCGUUAGGCCGAA AUCCGCUG
12557





888
GGAGCCAUU CCCACAAC
3148
GUUGUGGG CUGAUGAGGCCGUUAGGCCGAA AUGGCUCC
12558





889
GAGCCAUUC CCACAACA
3149
UGUUGUGG CUGAUGAGGCCGUUAGGCCGAA AAUGGCUC
12559





904
CAAUGUGUU CCACAGUG
3150
CACUGUGG CUGAUGAGGCCGUUAGGCCGAA ACACAUUG
12560





905
AAUGUGUUC CACAGUGU
3151
ACACUGUG CUGAUGAGGCCGUUAGGCCGAA AACACAUU
12561





914
CACAGUGUU CUUAAGAU
3152
AUCUUAAG CUGAUGAGGCCGUUAGGCCGAA ACACUGUG
12562





915
ACAGUGUUC UUAAGAUC
3153
GAUCUUAA CUGAUGAGGCCGUUAGGCCGAA AACACUGU
12563





917
AGUGUUCUU AAGAUCAA
3154
UUGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGAACACU
12564





918
GUGUUCUUA AGAUCAAC
3155
GUUGAUCU CUGAUGAGGCCGUUAGGCCGAA AAGAACAC
12565





923
CUUAAGAUC AACAAUGU
3156
ACAUUGUU CUGAUGAGGCCGUUAGGCCGAA AUCUUAAG
12566





953
AAGGGGCUC UACACCUG
3157
CAGGUGUA CUGAUGAGGCCGUUAGGCCGAA AGCCCCUU
12567





955
GGGGCUCUA CACCUGUC
3158
GACAGGUG CUGAUGAGGCCGUUAGGCCGAA AGAGCCCC
12568





963
ACACCUGUC GCGUGAAG
3159
CUUCACGC CUGAUGAGGCCGUUAGGCCGAA ACAGGUGU
12569





979
GAGUGGGUC CUCGUUCC
3160
GGAACGAG CUGAUGAGGCCGUUAGGCCGAA ACCCACUC
12570





982
UGGGUCCUC GUUCCAGU
3161
ACUGGAAC CUGAUGAGGCCGUUAGGCCGAA AGGACCCA
12571





985
GUCCUCGUU CCAGUCUU
3162
AAGACUGG CUGAUGAGGCCGUUAGGCCGAA ACGAGGAC
12572





986
UCCUCGUUC CAGUCUUU
3163
AAAGACUG CUGAUGAGGCCGUUAGGCCGAA AACGAGGA
12573





991
GUUCCAGUC UUUCAACA
3164
UGUUGAAA CUGAUGAGGCCGUUAGGCCGAA ACUGGAAC
12574





993
UCCAGUCUU UCAACACC
3165
GGUGUUGA CUGAUGAGGCCGUUAGGCCGAA AGACUGGA
12575





994
CCAGUCUUU CAACACCU
3166
AGGUGUUG CUGAUGAGGCCGUUAGGCCGAA AAGACUGG
12576





995
CAGUCUUUC AACACCUC
3167
GAGGUGUU CUGAUGAGGCCGUUAGGCCGAA AAAGACUG
12577





1003
CAACACCUC CGUGCAUG
3168
CAUGCACG CUGAUGAGGCCGUUAGGCCGAA AGGUGUUG
12578





1015
GCAUGUGUA UGAAAAAG
3169
CUUUUUCA CUGAUGAGGCCGUUAGGCCGAA ACACAUGC
12579





1027
AAAAGGAUU CAUCAGUG
3170
CACUGAUG CUGAUGAGGCCGUUAGGCCGAA AUCCUUUU
12580





1028
AAAGGAUUC AUCAGUGU
3171
ACACUGAU CUGAUGAGGCCGUUAGGCCGAA AAUCCUUU
12581





1031
GGAUUCAUC AGUGUGAA
3172
UUCACACU CUGAUGAGGCCGUUAGGCCGAA AUGAAUCC
12582





1044
UGAAACAUC GGAAGCAG
3173
CUGCUUCC CUGAUGAGGCCGUUAGGCCGAA AUGUUUCA
12583





1084
AAGACGGUC CUAUCGGC
3174
GCCGAUAG CUGAUGAGGCCGUUAGGCCGAA ACCGUCUU
12584





1087
ACGGUCCUA UCGGCUGU
3175
ACAGCCGA CUGAUGAGGCCGUUAGGCCGAA AGGACCGU
12585





1089
GGUCCUAUC GGCUGUCC
3176
GGACAGCC CUGAUGAGGCCGUUAGGCCGAA AUAGGACC
12586





1096
UCGGCUGUC CAUGAAAG
3177
CUUUCAUG CUGAUGAGGCCGUUAGGCCGAA ACAGCCGA
12587





1114
GAAGGCCUU CCCCUCCC
3178
GGGAGGGG CUGAUGAGGCCGUUAGGCCGAA AGGCCUUC
12588





1115
AAGGCCUUC CCCUCCCC
3179
GGGGAGGG CUGAUGAGGCCGUUAGGCCGAA AAGGCCUU
12589





1120
CUUCCCCUC CCCAGAAA
3180
UUUCUGGG CUGAUGAGGCCGUUAGGCCGAA AGGGGAAG
12590





1130
CCAGAAAUC GUAUGGUU
3181
AACCAUAC CUGAUGAGGCCGUUAGGCCGAA AUUUCUGG
12591





1133
GAAAUCGUA UGGUUAAA
3182
UUUAACCA CUGAUGAGGCCGUUAGGCCGAA ACGAUUUC
12592





1138
CGUAUGGUU AAAAGAUG
3183
CAUCUUUU CUGAUGAGGCCGUUAGGCCGAA ACCAUACG
12593





1139
GUAUGGUUA AAAGAUGG
210
CCAUCUUU CUGAUGAGGCCGUUAGGCCGAA AACCAUAC
9629





1150
AGAUGGCUC GCCUGCAA
3184
UUGCAGGC CUGAUGAGGCCGUUAGGCCGAA AGCCAUCU
12594





1162
UGCAACAUU GAAGUCUG
3185
CAGACUUC CUGAUGAGGCCGUUAGGCCGAA AUGUUGCA
12595





1168
AUUGAAGUC UGCUCGCU
3186
AGCGAGCA CUGAUGAGGCCGUUAGGCCGAA ACUUCAAU
12596





1173
AGUCUGCUC GCUAUUUG
3187
CAAAUAGC CUGAUGAGGCCGUUAGGCCGAA AGCAGACU
12597





1177
UGCUCGCUA UUUGGUAC
3188
GUACCAAA CUGAUGAGGCCGUUAGGCCGAA AGCGAGCA
12598





1179
CUCGCUAUU UGGUACAU
3189
AUGUACCA CUGAUGAGGCCGUUAGGCCGAA AUAGCGAG
12599





1180
UCGCUAUUU GGUACAUG
3190
CAUGUACC CUGAUGAGGCCGUUAGGCCGAA AAUAGCGA
12600





1184
UAUUUGGUA CAUGGCUA
3191
UAGCCAUG CUGAUGAGGCCGUUAGGCCGAA ACCAAAUA
12601





1192
ACAUGGCUA CUCAUUAA
3192
UUAAUGAG CUGAUGAGGCCGUUAGGCCGAA AGCCAUGU
12602





1195
UGGCUACUC AUUAAUUA
3193
UAAUUAAU CUGAUGAGGCCGUUAGGCCGAA AGUAGCCA
12603





1198
CUACUCAUU AAUUAUCA
3194
UGAUAAUU CUGAUGAGGCCGUUAGGCCGAA AUGAGUAG
12604





1199
UACUCAUUA AUUAUCAA
3195
UUGAUAAU CUGAUGAGGCCGUUAGGCCGAA AAUGAGUA
12605





1202
UCAUUAAUU AUCAAAGA
3196
UCUUUGAU CUGAUGAGGCCGUUAGGCCGAA AUUAAUGA
12606





1203
CAUUAAUUA UCAAAGAU
3197
AUCUUUGA CUGAUGAGGCCGUUAGGCCGAA AAUUAAUG
12607





1205
UUAAUUAUC AAAGAUGU
3198
ACAUCUUU CUGAUGAGGCCGUUAGGCCGAA AUAAUUAA
12608





1237
AGGGGACUA UACGAUCU
3199
AGAUCGUA CUGAUGAGGCCGUUAGGCCGAA AGUCCCCU
12609





1239
GGGACUAUA CGAUCUUG
3200
CAAGAUCG CUGAUGAGGCCGUUAGGCCGAA AUAGUCCC
12610





1244
UAUACGAUC UUGCUGGG
3201
CCCAGCAA CUGAUGAGGCCGUUAGGCCGAA AUCGUAUA
12611





1246
UACGAUCUU GCUGGGCA
3202
UGCCCAGC CUGAUGAGGCCGUUAGGCCGAA AGAUCGUA
12612





1256
CUGGGCAUA AAGCAGUC
3203
GACUGCUU CUGAUGAGGCCGUUAGGCCGAA AUGCCCAG
12613





1264
AAAGCAGUC AAGGCUAU
3204
AUAGCCUU CUGAUGAGGCCGUUAGGCCGAA ACUGCUUU
12614





1271
UCAAGGCUA UUUAAAAA
3205
UUUUUAAA CUGAUGAGGCCGUUAGGCCGAA AGCCUUGA
12615





1273
AAGGCUAUU UAAAAACC
3206
GGUUUUUA CUGAUGAGGCCGUUAGGCCGAA AUAGCCUU
12616





1274
AGGCUAUUU AAAAACCU
3207
AGGUUUUU CUGAUGAGGCCGUUAGGCCGAA AAUAGCCU
12617





1275
GGCUAUUUA AAAACCUC
3208
GAGGUUUU CUGAUGAGGCCGUUAGGCCGAA AAAUAGCC
12618





1283
AAAAACCUC ACUGCCAC
237
GUGGCAGU CUGAUGAGGCCGUUAGGCCGAA AGGUUUUU
9656





1293
CUGCCACUC UCAUUGUA
3209
UACAAUGA CUGAUGAGGCCGUUAGGCCGAA AGUGGCAG
12619





1295
GCCACUCUC AUUGUAAA
3210
UUUACAAU CUGAUGAGGCCGUUAGGCCGAA AGAGUGGC
12620





1298
ACUCUCAUU GUAAACGU
3211
ACGUUUAC CUGAUGAGGCCGUUAGGCCGAA AUGAGAGU
12621





1301
CUCAUUGUA AACGUGAA
3212
UUCACGUU CUGAUGAGGCCGUUAGGCCGAA ACAAUGAG
12622





1314
UGAAACCUC AGAUCUAC
3213
GUAGAUCU CUGAUGAGGCCGUUAGGCCGAA AGGUUUCA
12623





1319
CCUCAGAUC UACGAAAA
3214
UUUUCGUA CUGAUGAGGCCGUUAGGCCGAA AUCUGAGG
12624





1321
UCAGAUCUA CGAAAAGU
3215
ACUUUUCG CUGAUGAGGCCGUUAGGCCGAA AGAUCUGA
12625





1330
CGAAAAGUC CGUGUCCU
3216
AGGACACG CUGAUGAGGCCGUUAGGCCGAA ACUUUUCG
12626





1336
GUCCGUGUC CUCGCUUC
3217
GAAGCGAG CUGAUGAGGCCGUUAGGCCGAA ACACGGAC
12627





1339
CGUGUCCUC GCUUCCAA
3218
UUGGAAGC CUGAUGAGGCCGUUAGGCCGAA AGGACACG
12628





1343
UCCUCGCUU CCAAGCCC
3219
GGGCUUGG CUGAUGAGGCCGUUAGGCCGAA AGCGAGGA
12629





1344
CCUCGCUUC CAAGCCCA
3220
UGGGCUUG CUGAUGAGGCCGUUAGGCCGAA AAGCGAGG
12630





1356
GCCCACCUC UCUAUCCG
3221
CGGAUAGA CUGAUGAGGCCGUUAGGCCGAA AGGUGGGC
12631





1358
CCACCUCUC UAUCCGCU
3222
AGCGGAUA CUGAUGAGGCCGUUAGGCCGAA AGAGGUGG
12632





1360
ACCUCUCUA UCCGCUGG
3223
CCAGCGGA CUGAUGAGGCCGUUAGGCCGAA AGAGAGGU
12633





1362
CUCUCUAUC CGCUGGGC
3224
GCCCAGCG CUGAUGAGGCCGUUAGGCCGAA AUAGAGAG
12634





1382
AGACAAGUC CUCACUUG
3225
CAAGUGAG CUGAUGAGGCCGUUAGGCCGAA ACUUGUCU
12635





1385
CAAGUCCUC ACUUGCAC
3226
GUGCAAGU CUGAUGAGGCCGUUAGGCCGAA AGGACUUG
12636





1389
UCCUCACUU GCACCGUG
3227
CACGGUGC CUGAUGAGGCCGUUAGGCCGAA AGUGAGGA
12637





1399
CACCGUGUA UGGCAUCC
3228
GGAUGCCA CUGAUGAGGCCGUUAGGCCGAA ACACGGUG
12638





1406
UAUGGCAUC CCUCGGCC
3229
GGCCGAGG CUGAUGAGGCCGUUAGGCCGAA AUGCCAUA
12639





1410
GCAUCCCUC GGCCAACA
3230
UGUUGGCC CUGAUGAGGCCGUUAGGCCGAA AGGGAUGC
12640





1421
CCAACAAUC ACGUGGCU
3231
AGCCACGU CUGAUGAGGCCGUUAGGCCGAA AUUGUUGG
12641





1430
ACGUGGCUC UGGCACCC
3232
GGGUGCCA CUGAUGAGGCCGUUAGGCCGAA AGCCACGU
12642





1443
ACCCCUGUC ACCACAAU
3233
AUUGUGGU CUGAUGAGGCCGUUAGGCCGAA ACAGGGGU
12643





1452
ACCACAAUC ACUCCAAA
3234
UUUGGAGU CUGAUGAGGCCGUUAGGCCGAA AUUGUGGU
12644





1456
CAAUCACUC CAAAGAAA
3235
UUUCUUUG CUGAUGAGGCCGUUAGGCCGAA AGUGAUUG
12645





1468
AGAAAGGUA UGACUUCU
3236
AGAAGUCA CUGAUGAGGCCGUUAGGCCGAA ACCUUUCU
12646





1474
GUAUGACUU CUGCACUG
3237
CAGUGCAG CUGAUGAGGCCGUUAGGCCGAA AGUCAUAC
12647





1475
UAUGACUUC UGCACUGA
3238
UCAGUGCA CUGAUGAGGCCGUUAGGCCGAA AAGUCAUA
12648





1495
UGAAGAAUC CUUUAUCC
3239
GGAUAAAG CUGAUGAGGCCGUUAGGCCGAA AUUCUUCA
12649





1498
AGAAUCCUU UAUCCUGG
3240
CCAGGAUA CUGAUGAGGCCGUUAGGCCGAA AGGAUUCU
12650





1499
GAAUCCUUU AUCCUGGA
3241
UCCAGGAU CUGAUGAGGCCGUUAGGCCGAA AAGGAUUC
12651





1500
AAUCCUUUA UCCUGGAU
3242
AUCCAGGA CUGAUGAGGCCGUUAGGCCGAA AAAGGAUU
12652





1502
UCCUUUAUC CUGGAUCC
3243
GGAUCCAG CUGAUGAGGCCGUUAGGCCGAA AUAAAGGA
12653





1509
UCCUGGAUC CCAGCAGC
3244
GCUGCUGG CUGAUGAGGCCGUUAGGCCGAA AUCCAGGA
12654





1522
CAGCAACUU AGGAAACA
3245
UGUUUCCU CUGAUGAGGCCGUUAGGCCGAA AGUUGCUG
12655





1523
AGCAACUUA GGAAACAG
3246
CUGUUUCC CUGAUGAGGCCGUUAGGCCGAA AAGUUGCU
12656





1535
AACAGAAUU GAGAGCAU
280
AUGCUCUC CUGAUGAGGCCGUUAGGCCGAA AUUCUGUU
9699





1544
GAGAGCAUC UCUCAGCG
3247
CGCUGAGA CUGAUGAGGCCGUUAGGCCGAA AUGCUCUC
12657





1546
GAGCAUCUC UCAGCGCA
3248
UGCGCUGA CUGAUGAGGCCGUUAGGCCGAA AGAUGCUC
12658





1548
GCAUCUCUC AGCGCAUG
3249
CAUGCGCU CUGAUGAGGCCGUUAGGCCGAA AGAGAUGC
12659





1562
AUGACGGUC AUAGAAGG
3250
CCUUCUAU CUGAUGAGGCCGUUAGGCCGAA ACCGUCAU
12660





1565
ACGGUCAUA GAAGGAAC
3251
GUUCCUUC CUGAUGAGGCCGUUAGGCCGAA AUGACCGU
12661





1578
GAACAAAUA AGACGGUU
3252
AACCGUCU CUGAUGAGGCCGUUAGGCCGAA AUUUGUUC
12662





1586
AAGACGGUU AGCACAUU
3253
AAUGUGCU CUGAUGAGGCCGUUAGGCCGAA ACCGUCUU
12663





1587
AGACGGUUA GCACAUUG
3254
CAAUGUGC CUGAUGAGGCCGUUAGGCCGAA AACCGUCU
12664





1594
UAGCACAUU GGUGGUGG
3255
CCACCACC CUGAUGAGGCCGUUAGGCCGAA AUGUGCUA
12665





1609
GGCUGACUC UCAGACCC
3256
GGGUCUGA CUGAUGAGGCCGUUAGGCCGAA AGUCAGCC
12666





1611
CUGACUCUC AGACCCCU
3257
AGGGGUCU CUGAUGAGGCCGUUAGGCCGAA AGAGUCAG
12667





1625
CCUGGAAUC UACAGCUG
3258
CAGCUGUA CUGAUGAGGCCGUUAGGCCGAA AUUCCAGG
12668





1627
UGGAAUCUA CAGCUGCC
3259
GGCAGCUG CUGAUGAGGCCGUUAGGCCGAA AGAUUCCA
12669





1642
CCGGGCCUU CAAUAAAA
3260
UUUUAUUG CUGAUGAGGCCGUUAGGCCGAA AGGCCCGG
12670





1643
CGGGCCUUC AAUAAAAU
3261
AUUUUAUU CUGAUGAGGCCGUUAGGCCGAA AAGGCCCG
12671





1647
CCUUCAAUA AAAUAGGG
3262
CCCUAUUU CUGAUGAGGCCGUUAGGCCGAA AUUGAAGG
12672





1652
AAUAAAAUA GGGACUGU
3263
ACAGUCCC CUGAUGAGGCCGUUAGGCCGAA AUUUUAUU
12673





1673
AGAAACAUA AAAUUUUA
3264
UAAAAUUU CUGAUGAGGCCGUUAGGCCGAA AUGUUUCU
12674





1678
CAUAAAAUU UUAUGUCA
3265
UGACAUAA CUGAUGAGGCCGUUAGGCCGAA AUUUUAUG
12675





1679
AUAAAAUUU UAUGUCAC
3266
GUGACAUA CUGAUGAGGCCGUUAGGCCGAA AAUUUUAU
12676





1680
UAAAAUUUU AUGUCACA
3267
UGUGACAU CUGAUGAGGCCGUUAGGCCGAA AAAUUUUA
12677





1681
AAAAUUUUA UGUCACAG
3268
CUGUGACA CUGAUGAGGCCGUUAGGCCGAA AAAAUUUU
12678





1685
UUUUAUGUC ACAGAUGU
3269
ACAUCUGU CUGAUGAGGCCGUUAGGCCGAA ACAUAAAA
12679





1705
GAAUGGCUU UCACGUUU
3270
AAACGUGA CUGAUGAGGCCGUUAGGCCGAA AGCCAUUC
12680





1706
AAUGGCUUU CACGUUUC
3271
GAAACGUG CUGAUGAGGCCGUUAGGCCGAA AAGCCAUU
12681





1707
AUGGCUUUC ACGUUUCC
3272
GGAAACGU CUGAUGAGGCCGUUAGGCCGAA AAAGCCAU
12682





1712
UUUCACGUU UCCUUGGA
3273
UCCAAGGA CUGAUGAGGCCGUUAGGCCGAA ACGUGAAA
12683





1713
UUCACGUUU CCUUGGAA
3274
UUCCAAGG CUGAUGAGGCCGUUAGGCCGAA AACGUGAA
12684





1714
UCACGUUUC CUUGGAAA
3275
UUUCCAAG CUGAUGAGGCCGUUAGGCCGAA AAACGUGA
12685





1717
CGUUUCCUU GGAAAAGA
3276
UCUUUUCC CUGAUGAGGCCGUUAGGCCGAA AGGAAACG
12686





1756
GAAACUGUC CUGUGUGG
3277
CCACACAG CUGAUGAGGCCGUUAGGCCGAA ACAGUUUC
12687





1766
UGUGUGGUC AAUAAAUU
3278
AAUUUAUU CUGAUGAGGCCGUUAGGCCGAA ACCACACA
12688





1770
UGGUCAAUA AAUUCCUG
3279
CAGGAAUU CUGAUGAGGCCGUUAGGCCGAA AUUGACCA
12689





1774
CAAUAAAUU CCUGUACA
3280
UGUACAGG CUGAUGAGGCCGUUAGGCCGAA AUUUAUUG
12690





1775
AAUAAAUUC CUGUACAG
3281
CUGUACAG CUGAUGAGGCCGUUAGGCCGAA AAUUUAUU
12691





1780
AUUCCUGUA CAGAGACA
3282
UGUCUCUG CUGAUGAGGCCGUUAGGCCGAA ACAGGAAU
12692





1790
AGAGACAUG ACCUGGAU
3283
AUCCAGGU CUGAUGAGGCCGUUAGGCCGAA AUGUCUCU
12693





1791
GAGACAUUA CCUGGAUU
3284
AAUCCAGG CUGAUGAGGCCGUUAGGCCGAA AAUGUCUC
12694





1799
ACCUGGAUU CUGCUACG
3285
CGUAGCAG CUGAUGAGGCCGUUAGGCCGAA AUCCAGGU
12695





1800
CCUGGAUUC UGCUACGG
3286
CCGUAGCA CUGAUGAGGCCGUUAGGCCGAA AAUCCAGG
12696





1805
AUUCUGCUA CGGACAGU
3287
ACUGUCCG CUGAUGAGGCCGUUAGGCCGAA AGCAGAAU
12697





1814
CGGACAGUU AACAACAG
3288
CUGUUGUU CUGAUGAGGCCGUUAGGCCGAA ACUGUCCG
12698





1815
GGACAGUUA ACAACAGA
3289
UCUGUUGU CUGAUGAGGCCGUUAGGCCGAA AACUGUCC
12699





1836
UGCACCAUA GUAUCAGC
3290
GCUGAUAC CUGAUGAGGCCGUUAGGCCGAA AUGGUGCA
12700





1839
ACCAUAGUA UCAGCAAG
3291
CUUGCUGA CUGAUGAGGCCGUUAGGCCGAA ACUAUGGU
12701





1841
CAUAGUAUC AGCAAGCA
3292
UGCUUGCU CUGAUGAGGCCGUUAGGCCGAA AUACUAUG
12702





1866
CCACCACUC AAGAUUAC
3293
GUAAUCUU CUGAUGAGGCCGUUAGGCCGAA AGUGGUGG
12703





1872
CUCAAGAUU ACUCCAUC
3294
GAUGGAGU CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
12704





1873
UCAAGAUUA CUCCAUCA
3295
UGAUGGAG CUGAUGAGGCCGUUAGGCCGAA AAUCUUGA
12705





1876
AGAUUACUC CAUCACUC
3296
GAGUGAUG CUGAUGAGGCCGUUAGGCCGAA AGUAAUCU
12706





1880
UACUCCAUC ACUCUGAA
3297
UUCAGAGU CUGAUGAGGCCGUUAGGCCGAA AUGGAGUA
12707





1884
CCAUCACUC UGAACCUU
3298
AAGGUUCA CUGAUGAGGCCGUUAGGCCGAA AGUGAUGG
12708





1892
CUGAACCUU GUCAUCAA
3299
UUGAUGAC CUGAUGAGGCCGUUAGGCCGAA AGGUUCAG
12709





1895
AACCUUGUC AUCAAGAA
3300
UUCUUGAU CUGAUGAGGCCGUUAGGCCGAA ACAAGGUU
12710





1898
CUUGUCAUC AAGAACGU
3301
ACGUGCUU CUGAUGAGGCCGUUAGGCCGAA AUGACAAG
12711





1909
GAACGUGUC UCUAGAAG
3302
CUUCUAGA CUGAUGAGGCCGUUAGGCCGAA ACACGUUC
12712





1911
ACGUGUCUC UAGAAGAC
3303
GUCUUCUA CUGAUGAGGCCGUUAGGCCGAA AGACACGU
12713





1913
GUGUCUCUA GAAGACUC
3304
GAGUCUUC CUGAUGAGGCCGUUAGGCCGAA AGAGACAC
12714





1921
AGAAGACUC GGGCACCU
3305
AGGUGCCC CUGAUGAGGCCGUUAGGCCGAA AGUCUUCU
12715





1930
GGGCACCUA UGCGUGCA
3306
UGCACGCA CUGAUGAGGCCGUUAGGCCGAA AGGUGCCC
12716





1952
AGGAACAUA UACACAGG
3307
CCUGUGUA CUGAUGAGGCCGUUAGGCCGAA AUGUUCCU
12717





1954
GAACAUAUA CACAGGGG
3308
CCCCUGUG CUGAUGAGGCCGUUAGGCCGAA AUAUGUUC
12718





1970
GAAGACAUC CUUCGGAA
3309
UUCCGAAG CUGAUGAGGCCGUUAGGCCGAA AUGUCUUC
12719





1973
GACAUCCUU CGGAAGAC
3310
GUCUUCCG CUGAUGAGGCCGUUAGGCCGAA AGGAUGUC
12720





1974
ACAUCCUUC GGAAGACA
3311
UGUCUUCC CUGAUGAGGCCGUUAGGCCGAA AAGGAUGU
12721





1988
ACAGAAGUU CUCGUUAG
3312
CUAACGAG CUGAUGAGGCCGUUAGGCCGAA ACUUCUGU
12722





1989
CAGAAGUUC UCGUUAGA
3313
UCUAACGA CUGAUGAGGCCGUUAGGCCGAA AACUUCUG
12723





1991
GAAGUUCUC GUUAGAGA
3314
UCUCUAAC CUGAUGAGGCCGUUAGGCCGAA AGAACUUC
12724





1994
GUUCUCGUU AGAGAUUC
3315
GAAUCUCU CUGAUGAGGCCGUUAGGCCGAA ACGAGAAC
12725





1995
UUCUCGUUA GAGAUUCG
3316
CGAAUCUC CUGAUGAGGCCGUUAGGCCGAA AACGAGAA
12726





2001
UUAGAGAUU CGGAAGCG
3317
CGCUUCCG CUGAUGAGGCCGUUAGGCCGAA AUCUCUAA
12727





2002
UAGAGAUUC GGAAGCGC
3318
GCGCUUCC CUGAUGAGGCCGUUAGGCCGAA AAUCUCUA
12728





2021
CACCUGCUU CAAAACCU
3319
AGGUUUUG CUGAUGAGGCCGUUAGGCCGAA AGCAGGUG
12729





2022
ACCUGCUUC AAAACCUC
3320
GAGGUUUU CUGAUGAGGCCGUUAGGCCGAA AAGCAGGU
12730





2030
CAAAACCUC AGUGACUA
3321
UAGUCACU CUGAUGAGGCCGUUAGGCCGAA AGGUUUUG
12731





2038
CAGUGACUA CGAGGUCU
3322
AGACCUCG CUGAUGAGGCCGUUAGGCCGAA AGUCACUG
12732





2045
UACGAGGUC UCCAUCAG
3323
CUGAUGGA CUGAUGAGGCCGUUAGGCCGAA ACCUCGUA
12733





2047
CGAGGUCUC CAUCAGUG
3324
CACUGAUG CUGAUGAGGCCGUUAGGCCGAA AGACCUCG
12734





2051
GUCUCCAUC AGUGGCUC
3325
GAGCCACU CUGAUGAGGCCGUUAGGCCGAA AUGGAGAC
12735





2059
CAGUGGCUC UACGACCU
3326
AGGUCGUA CUGAUGAGGCCGUUAGGCCGAA AGCCACUG
12736





2061
GUGGCUCUA CGACCUUA
3327
UAAGGUCG CUGAUGAGGCCGUUAGGCCGAA AGAGCCAC
12737





2068
UACGACCUU AGACUGUC
3328
GACAGUCU CUGAUGAGGCCGUUAGGCCGAA AGGUCGUA
12738





2069
ACGACCUUA GACUGUCA
3329
UGACAGUC CUGAUGAGGCCGUUAGGCCGAA AAGGUCGU
12739





2076
UAGACUGUC AAGCUAGA
3330
UCUAGCUU CUGAUGAGGCCGUUAGGCCGAA ACAGUCUA
12740





2082
GUCAAGCUA GAGGUGUC
3331
GACACCUC CUGAUGAGGCCGUUAGGCCGAA AGCUUGAC
12741





2090
AGAGGUGUC CCCGCGCC
3332
GGCGCGGG CUGAUGAGGCCGUUAGGCCGAA ACACCUCU
12742





2100
CCGCGCCUC AGAUCACU
3333
AGUGAUCU CUGAUGAGGCCGUUAGGCCGAA AGGCGCGG
12743





2105
CCUCAGAUC ACUUGGUU
378
AACCAAGU CUGAUGAGGCCGUUAGGCCGAA AUCUGAGG
9797





2109
AGAUCACUU GGUUCAAA
3334
UUUGAACC CUGAUGAGGCCGUUAGGCCGAA AGUGAUCU
12744





2113
CACUUGGUU CAAAAACA
3335
UGUUUUUG CUGAUGAGGCCGUUAGGCCGAA ACCAAGUG
12745





2114
ACUUGGUUC AAAAACAA
3336
UUGUUUUU CUGAUGAGGCCGUUAGGCCGAA AACCAAGU
9800





2132
CACAAAAUA CAACAAGA
383
UCUUGUUG CUGAUGAGGCCGUUAGGCCGAA AUUUUGUG
9802





2150
CCGGGAAUU AUUUUAGG
3337
CCUAAAAU CUGAUGAGGCCGUUAGGCCGAA AUUCCCGG
12746





2151
CGGGAAUUA UUUUAGGA
3338
UCCUAAAA CUGAUGAGGCCGUUAGGCCGAA AAUUCCCG
12747





2153
GGAAUUAUU UUAGGACC
386
GGUCCUAA CUGAUGAGGCCGUUAGGCCGAA AUAAUUCC
9805





2154
GAAUUAUUU UAGGACCA
387
UGGUCCUA CUGAUGAGGCCGUUAGGCCGAA AAUAAUUC
9806





2155
AAUUAUUUU AGGACCAG
388
CUGGUCCU CUGAUGAGGCCGUUAGGCCGAA AAAUAAUU
9807





2156
AUUAUUUUA GGACCAGG
389
CCUGGUCC CUGAUGAGGCCGUUAGGCCGAA AAAAUAAU
9808





2179
CACGCUGUU UAUUGAAA
390
UUUCAAUA CUGAUGAGGCCGUUAGGCCGAA ACAGCGUG
9809





2180
ACGCUGUUU AUUGAAAG
391
CUUUCAAU CUGAUGAGGCCGUUAGGCCGAA AACAGCGU
9810





2181
CGCUGUUUA UUGAAAGA
392
UCUUUCAA CUGAUGAGGCCGUUAGGCCGAA AAACAGCG
9811





2183
CUGUUUAUU GAAAGAGU
393
ACUCUUUC CUGAUGAGGCCGUUAGGCCGAA AUAAACAG
9812





2192
GAAAGAGUC ACAGAGGA
3339
UCCUCUGU CUGAUGAGGCCGUUAGGCCGAA ACUCUUUC
12748





2213
GAGGGUGUC UAUAGGUG
3340
CACCUAUA CUGAUGAGGCCGUUAGGCCGAA ACACCCUC
12749





2215
GGGUGUCUA UAGGUGCC
3341
GGCACCUA CUGAUGAGGCCGUUAGGCCGAA AGACACCC
12750





2217
GUGUCUAUA GGUGCCGA
3342
UCGGCACC CUGAUGAGGCCGUUAGGCCGAA AUAGACAC
12751





2263
CGCAGCCUA CCUCACCG
3343
CGGUGAGG CUGAUGAGGCCGUUAGGCCGAA AGGCUGCG
12752





2267
GCCUACCUC ACCGUGCA
3344
UGCACGGU CUGAUGAGGCCGUUAGGCCGAA AGGUAGGC
12753





2284
AGGAACCUC AGACAAGU
3345
ACUUGUCU CUGAUGAGGCCGUUAGGCCGAA AGGUUCCU
12754





2293
AGACAAGUC AAACCUGG
3346
CCAGGUUU CUGAUGAGGCCGUUAGGCCGAA ACUUGUCU
12755





2309
GAGCUGAUC ACGCUCAC
3347
GUGAGCGU CUGAUGAGGCCGUUAGGCCGAA AUCAGCUC
12756





2315
AUCACGCUC ACGUGCAC
3348
GUGCACGU CUGAUGAGGCCGUUAGGCCGAA AGCGUGAU
12757





2342
GCGACCCUC UUUUGGCU
3349
AGCCAAAA CUGAUGAGGCCGUUAGGCCGAA AGGGUCGC
12758





2344
GACCCUCUU UUGGCUCC
3350
GGAGCCAA CUGAUGAGGCCGUUAGGCCGAA AGAGGGUC
12759





2345
ACCCUCUUU UGGCUCCU
3351
AGGAGCCA CUGAUGAGGCCGUUAGGCCGAA AAGAGGGU
12760





2346
CCCUCUUUU GGCUCCUU
3352
AAGGAGCC CUGAUGAGGCCGUUAGGCCGAA AAAGAGGG
12761





2351
UUUUGGCUC CUUCUAAC
3353
GUUAGAAG CUGAUGAGGCCGUUAGGCCGAA AGCCAAAA
12762





2354
UGGCUCCUU CUAACUCU
3354
AGAGUUAG CUGAUGAGGCCGUUAGGCCGAA AGGAGCCA
12763





2355
GGCUCCUUC UAACUCUC
3355
GAGAGUUA CUGAUGAGGCCGUUAGGCCGAA AAGGAGCC
12764





2357
CUCCUUCUA ACUCUCUU
3356
AAGAGAGU CUGAUGAGGCCGUUAGGCCGAA AGAAGGAG
12765





2361
UUCUAACUC UCUUCAUC
3357
GAUGAAGA CUGAUGAGGCCGUUAGGCCGAA AGUUAGAA
12766





2363
CUAACUCUC UUCAUCAG
3358
CUGAUGAA CUGAUGAGGCCGUUAGGCCGAA AGAGGUAG
12767





2365
AACUCUCUU CAUCAGAA
3359
UUCUGAUG CUGAUGAGGCCGUUAGGCCGAA AGAGAGUU
12768





2366
ACUCUCUUC AUCAGAAA
3360
UUUCUGAU CUGAUGAGGCCGUUAGGCCGAA AAGAGAGU
12769





2369
CUCUUCAUC AGAAAACU
3361
AGUUUUCU CUGAUGAGGCCGUUAGGCCGAA AUGAAGAG
12770





2386
GAAGCGGUC UUCUUCCG
3362
CGGAAGAA CUGAUGAGGCCGUUAGGCCGAA ACCGCUUC
12771





2388
AGCGGUCUU CUUCCGAA
3363
UUCGGAAG CUGAUGAGGCCGUUAGGCCGAA AGACCGCU
12772





2389
GCGGUCUUC UUCCGAAG
3364
CUUCGGAA CUGAUGAGGCCGUUAGGCCGAA AAGACCGC
12773





2391
GGUCUUCUU CCGAAGUA
3365
UACUUCGG CUGAUGAGGCCGUUAGGCCGAA AGAAGACC
12774





2392
GUCUUCUUC CGAAGUAA
3366
UUACUUCG CUGAUGAGGCCGUUAGGCCGAA AAGAAGAC
12775





2399
UCCGAAGUA AAGACAGA
3367
UCUGUCUU CUGAUGAGGCCGUUAGGCCGAA ACUUCGGA
12776





2410
GACAGACUA CCUGUCAA
3368
UUGACAGG CUGAUGAGGCCGUUAGGCCGAA AGUCUGUC
12777





2416
CUACCUGUC AAUCAUUA
3369
UAAUGAUU CUGAUGAGGCCGUUAGGCCGAA ACAGGUAG
12778





2420
CUGUCAAUC AUUAUGGA
3370
UCCAUAAU CUGAUGAGGCCGUUAGGCCGAA AUUGACAG
12779





2423
UCAAUCAUU AUGGACCC
3371
GGGUCCAU CUGAUGAGGCCGUUAGGCCGAA AUGAUUGA
12780





2424
CAAUCAUUA UGGACCCA
3372
UGGGUCCA CUGAUGAGGCCGUUAGGCCGAA AAUGAUUG
12781





2441
GAUGAAGUU CCCCUGGA
3373
UCCAGGGG CUGAUGAGGCCGUUAGGCCGAA ACUUCAUC
12782





2442
AUGAAGUUC CCCUGGAU
3374
AUCCAGGG CUGAUGAGGCCGUUAGGCCGAA AACUUCAU
12783





2473
GCUGCCCUA UGAUGCCA
3375
UGGCAUCA CUGAUGAGGCCGUUAGGCCGAA AGGGCAGC
12784





2494
GUGGGAGUU UGCACGGG
3376
CCCGUGCA CUGAUGAGGCCGUUAGGCCGAA ACUCCCAC
12785





2495
UGGGAGUUU GCACGGGA
3377
UCCCGUGC CUGAUGAGGCCGUUAGGCCGAA AACUCCCA
12786





2916
CUGAAACUA GGCAAAUC
3378
GAUUUGCC CUGAUGAGGCCGUUAGGCCGAA AGUUUCAG
12787





2524
AGGCAAAUC GCUCGGAA
3379
UUCCGAGC CUGAUGAGGCCGUUAGGCCGAA AUUUGCCU
12788





2528
AAAUCGCUC GGAAGAGG
3380
CCUCUUCC CUGAUGAGGCCGUUAGGCCGAA AGCGAUUU
12789





2541
GAGGGGCUU UUGGGAAA
3381
UUUCCCAA CUGAUGAGGCCGUUAGGCCGAA AGCCCCUC
12790





2542
AGGGGCUUU UGGGAAAG
3382
CUUUCCCA CUGAUGAGGCCGUUAGGCCGAA AAGCCCCU
12791





2543
GGGGCUUUU GGGAAAGU
3383
ACUUUCCC CUGAUGAGGCCGUUAGGCCGAA AAAGCCCC
12792





2552
GGGAAAGUC GUUCAAGC
3384
GCUUGAAC CUGAUGAGGCCGUUAGGCCGAA ACUUUCCC
12793





2555
AAAGUCGUU CAAGCCUC
3385
GAGGCUUG CUGAUGAGGCCGUUAGGCCGAA ACGACUUU
12794





2556
AAGUCGUUC AAGCCUCU
3386
AGAGGCUU CUGAUGAGGCCGUUAGGCCGAA AACGACUU
12795





2563
UCAAGCCUC UGCAUUUG
3387
CAAAUGCA CUGAUGAGGCCGUUAGGCCGAA AGGCUUGA
12796





2569
CUCUGCAUU UGGCAUUA
3388
UAAUGCCA CUGAUGAGGCCGUUAGGCCGAA AUGCAGAG
12797





2570
UCUGCAUUU GGCAUUAA
3389
UUAAUGCC CUGAUGAGGCCGUUAGGCCGAA AAUGCAGA
12798





2576
UUUGGCAUU AAGAAAUC
457
GAUUUCUU CUGAUGAGGCCGUUAGGCCGAA AUGCCAAA
9876





2577
UUGGCAUUA AGAAAUCA
458
UGAUUUCU CUGAUGAGGCCGUUAGGCCGAA AAUGCCAA
9877





2584
UAAGAAAUC ACCCACCU
3390
AGGUGGGU CUGAUGAGGCCGUUAGGCCGAA AUUUCUUA
12799





2617
GAAGAUGUU GAAAGAGG
3391
CCUCUUUC CUGAUGAGGCCGUUAGGCCGAA ACAUCUUC
12800





2644
CAGUGAGUA CAAAGCUC
3392
GAGCUUUG CUGAUGAGGCCGUUAGGCCGAA ACUCACUG
12801





2652
ACAAAGCUC UGAUGACC
3393
GGUCAUCA CUGAUGAGGCCGUUAGGCCGAA AGCUUUGU
12802





2666
ACCGAACUC AAGAUCUU
3394
AAGAUCUU CUGAUGAGGCCGUUAGGCCGAA AGUUCGGU
12803





2672
CUCAAGAUC UUGACCCA
3395
UGGGUCAA CUGAUGAGGCCGUUAGGCCGAA AUCUUGAG
12804





2674
CAAGAUCUU GACCCACA
3396
UGUGGGUC CUGAUGAGGCCGUUAGGCCGAA AGAUCUUG
12805





2684
ACCCACAUC GGCCAUCA
3397
UGAUGGCC CUGAUGAGGCCGUUAGGCCGAA AUGUGGGU
12806





2691
UCGGCCAUC AUCUGAAU
3398
AUUCAGAU CUGAUGAGGCCGUUAGGCCGAA AUGGCCGA
12807





2694
GCCAUCAUC UGAAUGUG
3399
CACAUUCA CUGAUGAGGCCGUUAGGCCGAA AUGAUGGC
12808





2705
AAUGUGGUU AACCUCCU
3400
AGGAGGUU CUGAUGAGGCCGUUAGGCCGAA ACCACAUU
12809





2706
AUGUGGUUA ACCUCCUG
3401
CAGGAGGU CUGAUGAGGCCGUUAGGCCGAA AACCACAU
12810





2711
GUUAACCUC CUGGGAGC
3402
GCUCCCAG CUGAUGAGGCCGUUAGGCCGAA AGGUUAAC
12811





2742
GAGGGCCUC UGAUGGUG
470
CACCAUCA CUGAUGAGGCCGUUAGGCCGAA AGGCCCUC
9889





2753
AUGGUGAUC GUGGAAUA
3403
UAUUCCAC CUGAUGAGGCCGUUAGGCCGAA AUCACCAU
12812





2761
CGUGGAAUA CUGCAAAU
3404
AUUUGCAG CUGAUGAGGCCGUUAGGCCGAA AUUCCACG
12813





2770
CUGCAAAUA CGGAAACC
3405
GGUUUCCG CUGAUGAGGCCGUUAGGCCGAA AUUUGCAG
12814





2782
AAACCUGUC CAACUACC
3406
GGUAGUUG CUGAUGAGGCCGUUAGGCCGAA ACAGGUUU
12815





2788
GUCCAACUA CCUCAAGA
3407
UCUUGAGG CUGAUGAGGCCGUUAGGCCGAA AGUUGGAC
12816





2792
AACUACCUC AAGAGCAA
479
UUGCUCUU CUGAUGAGGCCGUUAGGCCGAA AGGUAGUU
9898





2809
ACGUGACUU AUUCUGUC
3408
GACAGAAU CUGAUGAGGCCGUUAGGCCGAA AGUCACGU
12817





2810
CGUGACUUA UUCUGUCU
3409
AGACAGAA CUGAUGAGGCCGUUAGGCCGAA AAGUCACG
12818





2812
UGACUUAUU CUGUCUCA
3410
UGAGACAG CUGAUGAGGCCGUUAGGCCGAA AUAAGUCA
12819





2813
GACUUAUUC UGUCUCAA
3411
UUGAGACA CUGAUGAGGCCGUUAGGCCGAA AAUAAGUC
12820





2817
UAUUCUGUC UCAACAAG
3412
CUUGUUGA CUGAUGAGGCCGUUAGGCCGAA ACAGAAUA
12821





2819
UUCUGUCUC AACAAGGA
3413
UCCUUGUU CUGAUGAGGCCGUUAGGCCGAA AGACAGAA
12822





2836
CGCAGCCUU GCAUAUGG
3414
CCAUAUGC CUGAUGAGGCCGUUAGGCCGAA AGGCUGCG
12823





2841
CCUUGCAUA UGGAGCUC
3415
GAGCUCCA CUGAUGAGGCCGUUAGGCCGAA AUGCAAGG
12824





2849
AUGGAGCUC AAGAAAGA
3416
UCUUUCUU CUGAUGAGGCCGUUAGGCCGAA AGCUCCAU
12825





2900
CCCCGCCUA GACAGUGU
3417
ACACUGUC CUGAUGAGGCCGUUAGGCCGAA AGGCGGGG
12826





2909
GACAGUGUC AGCAGCUC
3418
GAGCUGCU CUGAUGAGGCCGUUAGGCCGAA ACACUGUC
12827





2917
CAGCAGCUC AAGUGUCA
3419
UGACACUU CUGAUGAGGCCGUUAGGCCGAA AGCUGCUG
12828





2924
UCAAGUGUC ACCAGCUC
3420
GAGCUGGU CUGAUGAGGCCGUUAGGCCGAA ACACUUGA
12829





2932
CACCAGCUC CAGCUUCC
3421
GGAAGCUG CUGAUGAGGCCGUUAGGCCGAA AGCUGGUG
12830





2938
CUCCAGCUU CCCUGAAG
3422
CUUCAGGG CUGAUGAGGCCGUUAGGCCGAA AGCUGGAG
12831





2939
UCCAGCUUC CCUGAAGA
3423
UCUUCAGG CUGAUGAGGCCGUUAGGCCGAA AAGCUGGA
12832





2982
ACGAGGAUU ACAGUGAG
3424
CUCACUGU CUGAUGAGGCCGUUAGGCCGAA AUCCUCGU
12833





2983
CGAGGAUUA CAGUGAGA
3425
UCUCACUG CUGAUGAGGCCGUUAGGCCGAA AAUCCUCG
12834





2993
AGUGAGAUC UCCAAGCA
3428
UGCUUGGA CUGAUGAGGCCGUUAGGCCGAA AUCUCACU
12835





2995
UGAGAUCUC CAAGCAGC
3427
GCUGCUUG CUGAUGAGGCCGUUAGGCCGAA AGAUCUCA
12836





3008
CAGCCCCUC ACCAUGGA
3428
UCCAUGGU CUGAUGAGGCCGUUAGGCCGAA AGGGGCUG
12837





3026
GACCUGAUU UCCUACAG
3429
CUGUAGGA CUGAUGAGGCCGUUAGGCCGAA AUCAGGUC
12838





3027
ACCUGAUUU CCUACAGU
3430
ACUGUAGG CUGAUGAGGCCGUUAGGCCGAA AAUCAGGU
12839





3028
CCUGAUUUC CUACAGUU
3431
AACUGUAG CUGAUGAGGCCGUUAGGCCGAA AAAUCAGG
12840





3031
GAUUUCCUA CAGUUUCC
3432
GGAAACUG CUGAUGAGGCCGUUAGGCCGAA AGGAAAUC
12841





3036
CCUACAGUU UCCAAGUG
3433
CACUUGGA CUGAUGAGGCCGUUAGGCCGAA ACUGUAGG
12842





3037
CUACAGUUU CCAAGUGG
3434
CCACUUGG CUGAUGAGGCCGUUAGGCCGAA AACUGUAG
12843





3038
UACAGUUUC CAAGUGGC
3435
GCCACUUG CUGAUGAGGCCGUUAGGCCGAA AAACUGUA
9938





3061
CAUGGAGUU UCUGUCCU
3436
AGGACAGA CUGAUGAGGCCGUUAGGCCGAA ACUCCAUG
12844





3062
AUGGAGUUU CUGUCCUC
3437
GAGGACAG CUGAUGAGGCCGUUAGGCCGAA AACUCCAU
12845





3063
UGGAGUUUC UGUCCUCC
3438
GGAGGACA CUGAUGAGGCCGUUAGGCCGAA AAACUCCA
12846





3067
GUUUCUGUC CUCCAGAA
3439
UUCUGGAG CUGAUGAGGCCGUUAGGCCGAA ACAGAAAC
12847





3070
UCUGUCCUC CAGAAAGU
3440
ACUUUCUG CUGAUGAGGCCGUUAGGCCGAA AGGACAGA
12848





3083
AAGUGCAUU CAUCGGGA
526
UCCCGAUG CUGAUGAGGCCGUUAGGCCGAA AUGCACUU
9945





3084
AGUGCAUUC AUCGGGAC
527
GUCCCGAU CUGAUGAGGCCGUUAGGCCGAA AAUGCACU
9946





3087
GCAUUCAUC GGGACCUG
528
CAGGUCCC CUGAUGAGGCCGUUAGGCCGAA AUGAAUGC
9947





3110
AGAAACAUC CUUUUAUC
3441
GAUAAAAG CUGAUGAGGCCGUUAGGCCGAA AUGUUUCU
9948





3113
AACAUCCUU UUAUCUGA
3442
UCAGAUAA CUGAUGAGGCCGUUAGGCCGAA AGGAUGUU
12849





3114
ACAUCCUUU UAUCUGAG
3443
CUCAGAUA CUGAUGAGGCCGUUAGGCCGAA AAGGAUGU
12850





3115
CAUCCUUUU AUCUGAGA
3444
UCUCAGAU CUGAUGAGGCCGUUAGGCCGAA AAAGGAUG
12851





3116
AUCCUUUUA UCUGAGAA
3445
UUCUCAGA CUGAUGAGGCCGUUAGGCCGAA AAAAGGAU
12852





3118
CCUUUUAUC UGAGAACA
3446
UGUUCUCA CUGAUGAGGCCGUUAGGCCGAA AUAAAAGG
12853





3140
GUGAAGAUU UGCGACUU
3447
AAGUCGCA CUGAUGAGGCCGUUAGGCCGAA AUCUUCAC
12854





3141
UGAAGAUUU GCGACUUU
3448
AAAGUCGC CUGAUGAGGCCGUUAGGCCGAA AAUCUUCA
12855





3148
UUGCGACUU UGGCCUGG
3449
CCAGGCCA CUGAUGAGGCCGUUAGGCCGAA AGUCGCAA
12856





3149
UGCGACUUU GGCCUGGC
3450
GCCAGGCC CUGAUGAGGCCGUUAGGCCGAA AAGUCGCA
12857





3165
CCCGGGAUA UUUAUAAG
542
CUUAUAAA CUGAUGAGGCCGUUAGGCCGAA AUCCCGGG
9961





3167
CGGGAUAUU UAUAAGAA
543
UUCUUAUA CUGAUGAGGCCGUUAGGCCGAA AUAUCCCG
9962





3168
GGGAUAUUU AUAAGAAC
544
GUUCUUAU CUGAUGAGGCCGUUAGGCCGAA AAUAUCCC
9963





3169
GGAUAUUUA UAAGAACC
545
GGUUCUUA CUGAUGAGGCCGUUAGGCCGAA AAAUAUCC
9964





3171
AUAUUUAUA AGAACCCU
3451
AGGGUUCU CUGAUGAGGCCGUUAGGCCGAA AUAAAUAU
12858





3183
ACCCUGAUU AUGUGAGG
3452
CCUCACAU CUGAUGAGGCCGUUAGGCCGAA AUCAGGGU
12859





3184
CCCUGAUUA UGUGAGGA
3453
UCCUCACA CUGAUGAGGCCGUUAGGCCGAA AAUCAGGG
12860





3201
GAGGAGAUA CUCGACUU
3454
AAGUCGAG CUGAUGAGGCCGUUAGGCCGAA AUCUCCUC
12861





3204
GAGAUACUC GACUUCCC
3455
GGGAAGUC CUGAUGAGGCCGUUAGGCCGAA AGUAUCUC
12862





3209
ACUCGACUU CCCCUAAA
3456
UUUAGGGG CUGAUGAGGCCGUUAGGCCGAA AGUCGAGU
12863





3210
CUCGACUUC CCCUAAAA
3457
UUUUAGGG CUGAUGAGGCCGUUAGGCCGAA AAGUCGAG
12864





3215
CUUCCCCUA AAAUGGAU
3458
AUCCAUUU CUGAUGAGGCCGUUAGGCCGAA AGGGGAAG
12865





3228
GGAUGGCUC CUGAAUCC
3459
GGAUUCAG CUGAUGAGGCCGUUAGGCCGAA AGCCAUCC
12866





3235
UCCUGAAUC CAUCUUUG
3460
CAAAGAUG CUGAUGAGGCCGUUAGGCCGAA AUUCAGGA
12867





3239
GAAUCCAUC UUUGACAA
3461
UUGUCAAA CUGAUGAGGCCGUUAGGCCGAA AUGGAUUC
12868





3241
AUCCAUCUU UGACAAGG
3462
CCUUGUCA CUGAUGAGGCCGUUAGGCCGAA AGAUGGAU
12869





3242
UCCAUCUUU GACAAGGU
3463
ACCUUGUC CUGAUGAGGCCGUUAGGCCGAA AAGAUGGA
12870





3251
GACAAGGUC UACAGCAC
3464
GUGCUGUA CUGAUGAGGCCGUUAGGCCGAA ACCUUGUC
12871





3253
CAAGGUCUA CAGCACCA
3465
UGGUGCUG CUGAUGAGGCCGUUAGGCCGAA AGACCUUG
12872





3277
UGUGUGGUC CUAUGGCG
3466
CGCCAUAG CUGAUGAGGCCGUUAGGCCGAA ACCACACA
12873





3280
GUGGUCCUA UGGCGUGU
3467
ACACGCCA CUGAUGAGGCCGUUAGGCCGAA AGGACCAC
12874





3289
UGGCGUGUU GCUGUGGG
3468
CCCACAGC CUGAUGAGGCCGUUAGGCCGAA ACACGCCA
12875





3302
UGGGAGAUC UUCUCCUU
3469
AAGGAGAA CUGAUGAGGCCGUUAGGCCGAA AUCUCCCA
12876





3304
GGAGAUCUU CUCCUUAG
3470
CUAAGGAG CUGAUGAGGCCGUUAGGCCGAA AGAUCUCC
12877





3305
GAGAUCUUC UCCUUAGG
3471
CCUAAGGA CUGAUGAGGCCGUUAGGCCGAA AAGAUCUC
12878





3307
GAUCUUCUC CUUAGGGG
3472
CCCCUAAG CUGAUGAGGCCGUUAGGCCGAA AGAAGAUC
12879





3310
CUUCUCCUU AGGGGGUU
3473
AACCCCCU CUGAUGAGGCCGUUAGGCCGAA AGGAGAAG
12880





3311
UUCUCCUUA GGGGGUUC
3474
GAACCCCC CUGAUGAGGCCGUUAGGCCGAA AAGGAGAA
12881





3328
UAGGGGGUU CUCCAUAC
3475
GUAUGGAG CUGAUGAGGCCGUUAGGCCGAA ACCCCCUA
12882





3319
AGGGGGUUC UCCAUACC
3476
GGUAUGGA CUGAUGAGGCCGUUAGGCCGAA AACCCCCU
12883





3321
GGGGUUCUC CAUACCCA
3477
UGGGUAUG CUGAUGAGGCCGUUAGGCCGAA AGAACCCC
12884





3325
UUCUCCAUA CCCAGGAG
3478
CUCCUGGG CUGAUGAGGCCGUUAGGCCGAA AUGGAGAA
12885





3352
UGAAGACUU CUGCAGCC
3479
GGCUGCAG CUGAUGAGGCCGUUAGGCCGAA AGUCUUCA
12886





3353
GAAGACUUC UGCAGCCG
3480
CGGCUGCA CUGAUGAGGCCGUUAGGCCGAA AAGUCUUC
12887





3397
CCCGGAGUA UGCCACAC
3481
GUGUGGCA CUGAUGAGGCCGUUAGGCCGAA ACUCCGGG
12888





3413
CCUGAAAUC UACCAAAU
3482
AUUUGGUA CUGAUGAGGCCGUUAGGCCGAA AUUUCAGG
12889





3415
UGAAAUCUA CCAAAUCA
3483
UGAUUUGG CUGAUGAGGCCGUUAGGCCGAA AGAUUUCA
12890





3422
UACCAAAUC AUGGUGGA
3484
UCCAACAU CUGAUGAGGCCGUUAGGCCGAA AUUUGGUA
12891





3427
AAUCAUGUU GGAUUGCU
3485
AGCAAUCC CUGAUGAGGCCGUUAGGCCGAA ACAUGAUU
12892





3432
UGUUGGAUU GCUGGCAC
3486
GUGCCAGC CUGAUGAGGCCGUUAGGCCGAA AUCCAACA
12893





3466
GCCCCGGUU UGCUGAAC
3487
GUUCAGCA CUGAUGAGGCCGUUAGGCCGAA ACCGGGGC
12894





3467
CCCCGGUUU GCUGAACU
3488
AGUUCAGC CUGAUGAGGCCGUUAGGCCGAA AACCGGGG
12895





3476
GCUGAACUU GUGGAGAA
3489
UUCUCCAC CUGAUGAGGCCGUUAGGCCGAA AGUUCAGC
12896





3488
GAGAAACUU GGUGACCU
3490
AGGUCACC CUGAUGAGGCCGUUAGGCCGAA AGUUUCUC
12897





3500
GACCUGCUU CAAGCCAA
3491
UUGGCUUG CUGAUGAGGCCGUUAGGCCGAA AGCAGGUC
12898





3501
ACCUGCUUC AAGCCAAC
3492
GUUGGCUU CUGAUGAGGCCGUUAGGCCGAA AAGCAGGU
12899





3512
GCCAACGUC CAACAGGA
3493
UCCUGUUG CUGAUGAGGCCGUUAGGCCGAA ACGUUGGC
12900





3531
GGAAAGAUU ACAUCCCC
3494
GGGGAUGU CUGAUGAGGCCGUUAGGCCGAA AUCUUUCC
12901





3532
GAAAGAUUA CAUCCCCC
3495
GGGGGAUG CUGAUGAGGCCGUUAGGCCGAA AAUCUUUC
12902





3536
GAUUACAUC CCCCUCAA
3496
UUGAGGGG CUGAUGAGGCCGUUAGGCCGAA AUGUAAUC
12903





3542
AUCCCCCUC AAUGCCAU
3497
AUGGCAUU CUGAUGAGGCCGUUAGGCCGAA AGGGGGAU
12904





3551
AAUGCCAUA CUGACUAG
3498
CUAGUCAG CUGAUGAGGCCGUUAGGCCGAA AUGGCAUU
12905





3558
UACUGACUA GAAACAGU
3499
ACUGUUUC CUGAUGAGGCCGUUAGGCCGAA AGUCAGUA
12906





3567
GAAACAGUA GCUUCACA
3500
UGUGAAGC CUGAUGAGGCCGUUAGGCCGAA ACUGUUUC
12907





3571
CAGUAGCUU CACAUACU
3501
AGUAUGUG CUGAUGAGGCCGUUAGGCCGAA AGCUACUG
12908





3572
AGUAGCUUC ACAUACUC
3502
GAGUAUGU CUGAUGAGGCCGUUAGGCCGAA AAGCUACU
12909





3577
CUUCACAUA CUCGACCC
3503
GGGUCGAG CUGAUGAGGCCGUUAGGCCGAA AUGUGAAG
12910





3580
CACAUACUC GACCCCCA
3504
UGGGGGUC CUGAUGAGGCCGUUAGGCCGAA AGUAUGUG
12911





3592
CCCCACCUU CUCUGAGG
3505
CCUCAGAG CUGAUGAGGCCGUUAGGCCGAA AGGUGGGG
12912





3593
CCCACCUUC UCUGAGGA
3506
UCCUCAGA CUGAUGAGGCCGUUAGGCCGAA AAGGUGGG
12913





3595
CACCUUCUC UGAGGACC
3507
GGUCCUCA CUGAUGAGGCCGUUAGGCCGAA AGAAGGUG
12914





3605
GAGGACCUU UUCAAGGA
3508
UCCUUGAA CUGAUGAGGCCGUUAGGCCGAA AGGUCCUC
12915





3606
AGGACCUUU UCAAGGAC
3509
GUCCUUGA CUGAUGAGGCCGUUAGGCCGAA AAGGUCCU
12916





3607
GGACCUUUU CAAGGACG
3510
CGUCCUUG CUGAUGAGGCCGUUAGGCCGAA AAAGGUCC
12917





3608
GACCUUUUC AAGGACGG
3511
CCGUCCUU CUGAUGAGGCCGUUAGGCCGAA AAAAGGUC
12918





3619
GGACGGCUU UGCAGAUC
3512
GAUCUCCA CUGAUGAGGCCGUUAGGCCGAA AGCCGUCC
12919





3620
GACGGCUUU GCAGAUCC
3513
GGAUCUGC CUGAUGAGGCCGUUAGGCCGAA AAGCCGUC
12920





3627
UUGCAGAUC CACAUUUU
3514
AAAAUGUG CUGAUGAGGCCGUUAGGCCGAA AUCUGCAA
12921





3633
AUCCACAUU UUCAUUCC
3515
GGAAUGAA CUGAUGAGGCCGUUAGGCCGAA AUGUGGAU
12922





3634
UCCACAUUU UCAUUCCG
3516
CGGAAUGA CUGAUGAGGCCGUUAGGCCGAA AAUGUGGA
12923





3635
CCACAUUUU CAUUCCGG
3517
CCGGAAUG CUGAUGAGGCCGUUAGGCCGAA AAAUGUGG
12924





3636
CACAUUUUC AUUCCGGA
3518
UCCGGAAU CUGAUGAGGCCGUUAGGCCGAA AAAAUGUG
12925





3639
AUUUUCAUU CCGGAAGC
3519
GCUUCCGG CUGAUGAGGCCGUUAGGCCGAA AUGAAAAU
12926





3640
UUUUCAUUC CGGAAGCU
3520
AGCUUCCG CUGAUGAGGCCGUUAGGCCGAA AAUGAAAA
12927





3649
CGGAAGCUC UGAUGAUG
3521
CAUCAUCA CUGAUGAGGCCGUUAGGCCGAA AGCUUCCG
12928





3664
UGUGAGAUA UGUAAACG
3522
CGUUUACA CUGAUGAGGCCGUUAGGCCGAA AUCUCACA
12929





3668
AGAUAUGUA AACGCUUU
3523
AAAGCGUU CUGAUGAGGCCGUUAGGCCGAA ACAUAUCU
12930





3675
UAAACGCUU UCAAAUUC
3524
GAAUUUGA CUGAUGAGGCCGUUAGGCCGAA AGCGUUUA
12931





3676
AAACGCUUU CAAAUUCA
3525
UGAAUUUG CUGAUGAGGCCGUUAGGCCGAA AAGCGUUU
12932





3677
AACGCUUUC AAAUUCAU
3526
AUGAAUUU CUGAUGAGGCCGUUAGGCCGAA AAAGCGUU
12933





3682
UUUCAAAUU CAUGAGCC
3527
GGCUCAUG CUGAUGAGGCCGUUAGGCCGAA AUUUGAAA
12934





3683
UUCAAAUUC AUGAGCCU
3528
AGGCUCAU CUGAUGAGGCCGUUAGGCCGAA AAUUUGAA
12935





3701
GAAAGAAUC AAAACCUU
637
AAGGUUUU CUGAUGAGGCCGUUAGGCCGAA AUUCUUUC
10056





3709
CAAAACCUU UGAGGAGC
3529
GCUCCUCA CUGAUGAGGCCGUUAGGCCGAA AGGUUUUG
12936





3710
AAAACCUUU GAGGAGCU
3530
AGCUCCUC CUGAUGAGGCCGUUAGGCCGAA AAGGUUUU
12937





3719
GAGGAGCUU UCACCGAA
3531
UUCGGUGA CUGAUGAGGCCGUUAGGCCGAA AGCUCCUC
12938





3720
AGGAGCUUU CACCGAAC
3532
GUUCGGUG CUGAUGAGGCCGUUAGGCCGAA AAGCUCCU
12939





3721
GGAGCUUUC ACCGAACU
3533
AGUUCGGU CUGAUGAGGCCGUUAGGCCGAA AAAGCUCC
12940





3730
ACCGAACUC CACCUCCA
3534
UGGAGGUG CUGAUGAGGCCGUUAGGCCGAA AGUUCGGU
12941





3736
CUCCACCUC CAUGUUUG
3535
CAAACAUG CUGAUGAGGCCGUUAGGCCGAA AGGUGGAG
12942





3742
CUCCAUGUU UGAGGACU
3536
AGUCCUCA CUGAUGAGGCCGUUAGGCCGAA ACAUGGAG
12943





3743
UCCAUGUUU GAGGACUA
3537
UAGUCCUC CUGAUGAGGCCGUUAGGCCGAA AACAUGGA
12944





3751
UGAGGACUA UCAGCUGG
3538
CCAGCUGA CUGAUGAGGCCGUUAGGCCGAA AGUCCUCA
12945





3753
AGGACUAUC AGCUGGAC
3539
GUCCAGCU CUGAUGAGGCCGUUAGGCCGAA AUAGUCCU
12946





3765
UGGACACUA GCACUCUG
3540
CAGAGUGC CUGAUGAGGCCGUUAGGCCGAA AGUGUCCA
12947





3771
CUAGCACUC UGCUGGGC
3541
GCCCAGCA CUGAUGAGGCCGUUAGGCCGAA AGUGCUAG
12948





3781
GCUGGGCUC CCCCUUGC
3542
GCAAGGGG CUGAUGAGGCCGUUAGGCCGAA AGCCCAGC
12949





3787
CUCCCCCUU GCUGAAGC
3543
GCUUCAGC CUGAUGAGGCCGUUAGGCCGAA AGGGGGAG
12950





3799
GAAGCGGUU CACCUGGA
3544
UCCAGGUG CUGAUGAGGCCGUUAGGCCGAA ACCGCUUC
12951





3800
AAGCGGUUC ACCUGGAC
3545
GUCCAGGU CUGAUGAGGCCGUUAGGCCGAA AACCGCUU
12952





3829
CAAGGCCUC CAUGAAGA
3546
UCUUCAUG CUGAUGAGGCCGUUAGGCCGAA AGGCCUUG
12953





3839
AUGAAGAUA GACUUGAG
3547
CUCAAGUC CUGAUGAGGCCGUUAGGCCGAA AUCUUCAU
12954





3844
GAUAGACUU GAGAAUAG
3548
CUAUUCUC CUGAUGAGGCCGUUAGGCCGAA AGUCUAUC
12955





3851
UUGAGAAUA GCGAGUAA
3549
UUACUCGC CUGAUGAGGCCGUUAGGCCGAA AUUCUCAA
12956





3858
UAGCGAGUA AAAGCAAG
3550
CUUGCUUU CUGAUGAGGCCGUUAGGCCGAA ACUCGCUA
12957





3878
GCGGGACUU UCCGAUCU
3551
AGAUCGGA CUGAUGAGGCCGUUAGGCCGAA AGUCCCGC
12958





3879
CGGGACUUU CCGAUCUG
3552
CAGAUCGG CUGAUGAGGCCGUUAGGCCGAA AAGUCCCG
12959





3880
GGGACUUUC CGAUCUGC
3553
GCAGAUCG CUGAUGAGGCCGUUAGGCCGAA AAAGUCCC
12960





3885
UUUCCGAUC UGCCGAGG
3554
CCUCGGCA CUGAUGAGGCCGUUAGGCCGAA AUCGGAAA
12961





3901
GCCCAGCUU CUGCUUCU
3555
AGAAGCAG CUGAUGAGGCCGUUAGGCCGAA AGCUGGGC
12962





3902
CCCAGCUUC UGCUUCUC
3556
GAGAAGCA CUGAUGAGGCCGUUAGGCCGAA AAGCUGGG
12963





3907
CUUCUGCUU CUCCAGCU
3557
AGCUGGAG CUGAUGAGGCCGUUAGGCCGAA AGCAGAAG
12964





3908
UUCUGCUUC UCCAGCUG
3558
CAGCUGGA CUGAUGAGGCCGUUAGGCCGAA AAGCAGAA
12965





3910
CUGCUUCUC CAGCUGUG
3559
CACAGCUG CUGAUGAGGCCGUUAGGCCGAA AGAAGCAG
12966





3926
GGCCACAUC AGGCCCGU
3560
ACGGGCCU CUGAUGAGGCCGUUAGGCCGAA AUGUGGCC
12967





3949
CGAUGAAUC UGAGCUGG
3561
CCAGCUCA CUGAUGAGGCCGUUAGGCCGAA AUUCAUCG
12968





3967
AAAGGAGUC CUGCUGUU
3562
AACAGCAG CUGAUGAGGCCGUUAGGCCGAA ACUCCUUU
12969





3975
CCUGCUGUU CUCCACCC
3563
GGGUGGAG CUGAUGAGGCCGUUAGGCCGAA ACAGCAGG
12970





3976
CUGCUGUUC UCCACCCC
3564
GGGGUGGA CUGAUGAGGCCGUUAGGCCGAA AACAGCAG
12971





3978
GCUGUUCUC CACCCCCA
3565
UGGGGGUG CUGAUGAGGCCGUUAGGCCGAA AGAACAGC
12972





3991
CCCAGACUA CAACUCCG
3566
CGGAGUUG CUGAUGAGGCCGUUAGGCCGAA AGUCUGGG
12973





3997
CUACAACUC CGUGGUGU
3567
ACACCACG CUGAUGAGGCCGUUAGGCCGAA AGUUGUAG
12974





4006
CGUGGUGUU GUACUCCU
3568
AGGAGUAC CUGAUGAGGCCGUUAGGCCGAA ACACCACG
12975





4009
GGUGUUGUA CUCCUCCC
3569
GGGAGGAG CUGAUGAGGCCGUUAGGCCGAA ACAACACC
12976





4012
GUUGUACUC CUCCCCGC
3570
GCGGGGAG CUGAUGAGGCCGUUAGGCCGAA AGUACAAC
12977





4015
GUACUCCUC CCCGCCCG
3571
CGGGCGGG CUGAUGAGGCCGUUAGGCCGAA AGGAGUAC
12978





4027
GCCCGCCUA AAGCUUCU
3572
AGAAGCUU CUGAUGAGGCCGUUAGGCCGAA AGGCGGGC
12979





4033
CUAAAGCUU CUCACCAG
3573
CUGGUGAG CUGAUGAGGCCGUUAGGCCGAA AGCUUUAG
12980





4034
UAAAGCUUC UCACCAGC
3574
GCUGGUGA CUGAUGAGGCCGUUAGGCCGAA AAGCUUUA
12981





4036
AAGCUUCUC ACCAGCCC
3575
GGGCUGGU CUGAUGAGGCCGUUAGGCCGAA AGAAGCUU
12982





4066
CUGACAGUA UUAUACAU
3576
AUGUAUAA CUGAUGAGGCCGUUAGGCCGAA ACUGUCAG
12983





4068
GACAGUAUU AUACAUCU
3577
AGAUGUAU CUGAUGAGGCCGUUAGGCCGAA AUACUGUC
12984





4069
ACAGUAUUA UACAUCUA
3578
UAGAUGUA CUGAUGAGGCCGUUAGGCCGAA AAUACUGU
12985





4071
AGUAUUAUA CAUCUAUG
3579
CAUAGAUG CUGAUGAGGCCGUUAGGCCGAA AUAAUACU
12986





4075
UUAUACAUC UAUGAGUU
3580
AACUCAUA CUGAUGAGGCCGUUAGGCCGAA AUGUAUAA
12987





4077
AUACAUCUA UGAGUUUA
3581
UAAACUCA CUGAUGAGGCCGUUAGGCCGAA AGAUGUAU
12988





4083
CUAUGAGUU UACACCUA
3582
UAGGUGUA CUGAUGAGGCCGUUAGGCCGAA ACUCAUAG
12989





4084
UAUGAGUUU ACACCUAU
3583
AUAGGUGU CUGAUGAGGCCGUUAGGCCGAA AACUCAUA
12990





4085
AUGAGUUUA CACCUAUU
3584
AAUAGGUG CUGAUGAGGCCGUUAGGCCGAA AAACUCAU
12991





4091
UUACACCUA UUCCGCUC
3585
GAGCGGAA CUGAUGAGGCCGUUAGGCCGAA AGGUGUAA
12992





4093
ACACCUAUU CCGCUCCA
3586
UGGAGCGG CUGAUGAGGCCGUUAGGCCGAA AUAGGUGU
12993





4094
CACCUAUUC CGCUCCAC
3587
GUGGAGCG CUGAUGAGGCCGUUAGGCCGAA AAUAGGUG
12994





4099
AUUCCGCUC CACAGGAG
3588
CUCCUGUG CUGAUGAGGCCGUUAGGCCGAA AGCGGAAU
12995





4117
CAGCUGCUU UUCGUGAC
3589
GUCACGAA CUGAUGAGGCCGUUAGGCCGAA AGCAGCUG
12996





4118
AGCUGCUUU UCGUGACC
3590
GGUCACGA CUGAUGAGGCCGUUAGGCCGAA AAGCAGCU
12997





4119
GCUGCUUUU CGUGACCU
3591
AGGUCACG CUGAUGAGGCCGUUAGGCCGAA AAAGCAGC
12998





4120
CUGCUUUUC GUGACCUU
3592
AAGGUCAC CUGAUGAGGCCGUUAGGCCGAA AAAAGCAG
12999





4128
CGUGACCUU UAAUCGUG
3593
CACGAUUA CUGAUGAGGCCGUUAGGCCGAA AGGUCACG
13000





4129
GUGACCUUU AAUCGUGC
3594
GCACGAUU CUGAUGAGGCCGUUAGGCCGAA AAGGUCAC
13001





4130
UGACCUUUA AUCGUGCU
3595
AGCACGAU CUGAUGAGGCCGUUAGGCCGAA AAAGGUCA
13002





4133
CCUUUAAUC GUGCUUUU
3596
AAAAGCAC CUGAUGAGGCCGUUAGGCCGAA AUUAAAGG
13003





4139
AUCGUGCUU UUUEGUUU
3597
AAACAAAA CUGAUGAGGCCGUUAGGCCGAA AGCACGAU
13004





4140
UCGUGCUUU UUUGUUUU
3598
AAAACAAA CUGAUGAGGCCGUUAGGCCGAA AAGCACGA
13005





4141
CGUGCUUUU UUGUUUUU
3599
AAAAACAA CUGAUGAGGCCGUUAGGCCGAA AAAGCACG
13006





4142
GUGCUUUUU UGUUUUUU
3600
AAAAAACA CUGAUGAGGCCGUUAGGCCGAA AAAAGCAC
13007





4143
UGCUUUUUU GUUUUUUG
3601
CAAAAAAC CUGAUGAGGCCGUUAGGCCGAA AAAAAGCA
13008





4146
UUUUUUGUU UUUUGUUU
3602
AAACAAAA CUGAUGAGGCCGUUAGGCCGAA ACAAAAAA
13009





4147
UUUUUGUUU UUUGUUJU
3603
AAAACAAA CUGAUGAGGCCGUUAGGCCGAA AACAAAAA
13010





4148
UUUUGUUUU UUGUUUUG
3604
CAAAACAA CUGAUGAGGCCGUUAGGCCGAA AAACAAAA
13011





4149
UUUGUUUUU UGUUUUGU
3605
ACAAAACA CUGAUGAGGCCGUUAGGCCGAA AAAACAAA
13012





4150
UUGUUUUUU GUUUUGUU
3606
AACAAAAC CUGAUGAGGCCGUUAGGCCGAA AAAAACAA
13013





4153
UUUUUUGUU UUGUUUGU
3607
ACAAACAA CUGAUGAGGCCGUUAGGCCGAA ACAAAAAA
13014





4154
UUUUUGUUU UGUUUGUU
3608
AACAAACA CUGAUGAGGCCGUUAGGCCGAA AACAAAAA
13015





4255
UUUUGUUUU GUUUGUUG
3609
CAACAAAC CUGAUGAGGCCGUUAGGCCGAA AAACAAAA
13016





4258
UGUUUUGUU UGUUGUUG
3610
CAACAACA CUGAUGAGGCCGUUAGGCCGAA ACAAAACA
13017





4259
GUUUUGUUU GUUGUUGC
3611
GCAACAAC CUGAUGAGGCCGUUAGGCCGAA AACAAAAC
13018





4162
UUGUUUGUU GUUGCUGU
3612
ACAGCAAC CUGAUGAGGCCGUUAGGCCGAA ACAAACAA
13019





4165
UUUGUUGUU GCUGUUUU
3613
AAAACAGC CUGAUGAGGCCGUUAGGCCGAA ACAACAAA
13020





4171
GUUGCUGUU UUGACUAA
3614
UUAGUCAA CUGAUGAGGCCGUUAGGCCGAA ACAGCAAC
13021





4172
UUGCUGUUU UGACUAAC
3615
GUUAGUCA CUGAUGAGGCCGUUAGGCCGAA AACAGCAA
13022





4173
UGCUGUUUU GACUAACA
3616
UGUUAGUC CUGAUGAGGCCGUUAGGCCGAA AAACAGCA
13023





4178
UUUUGACUA ACAAGAAU
737
AUUCUUGU CUGAUGAGGCCGUUAGGCCGAA AGUCAAAA
10156





4189
AAGAAUGUA ACCCCAGU
3617
ACUGGGGU CUGAUGAGGCCGUUAGGCCGAA ACAUUCUU
13024





4198
ACCCCAGUU AGUGACGU
3618
ACGUCACU CUGAUGAGGCCGUUAGGCCGAA ACUGGGGU
13025





4199
CCCCAGUUA GUGACGUG
3619
CACGUCAC CUGAUGAGGCCGUUAGGCCGAA AACUGGGG
13026





4216
UGAAGAAUA CUAUUGUU
3620
AACAAUAG CUGAUGAGGCCGUUAGGCCGAA AUUCUUCA
13027





4219
AGAAUACUA UUGUUAGA
3621
UCUAACAA CUGAUGAGGCCGUUAGGCCGAA AGUAUUCU
13028





4221
AAUACUAUU GUUAGAGA
3622
UCUCUAAC CUGAUGAGGCCGUUAGGCCGAA AUAGUAUU
13029





4224
ACUAUUGUU AGAGAAAU
3623
AUUUCUCU CUGAUGAGGCCGUUAGGCCGAA ACAAUAGU
13030





4225
CUAUUGUUA GAGAAAUC
3624
GAUUUCUC CUGAUGAGGCCGUUAGGCCGAA AACAAUAG
13031





4233
AGAGAAAUC CCCCCCGC
3625
GCGGGGGG CUGAUGAGGCCGUUAGGCCGAA AUUUCUCU
13032





4249
CAAAGCCUC AGGGUAAC
3626
GUUACCCU CUGAUGAGGCCGUUAGGCCGAA AGGCUUUG
13033





4255
CUCAGGGUA ACCUGGAC
3627
GUCCAGGU CUGAUGAGGCCGUUAGGCCGAA ACCCUGAG
13034





4282
AGGUGCCUC UGGCGACC
3628
GGUCGCCA CUGAUGAGGCCGUUAGGCCGAA AGGCACCU
13035





4323
CCCACCCUC CCUGCAGC
3629
GCUGCAGG CUGAUGAGGCCGUUAGGCCGAA AGGGUGGG
13036





4341
GUGGGACUA GAGGCAGU
3630
ACUGCCUC CUGAUGAGGCCGUUAGGCCGAA AGUCCCAC
13037





4350
GAGGCAGUA AGCCCAUU
3631
AAUGGGCU CUGAUGAGGCCGUUAGGCCGAA ACUGCCUC
13038





4358
AAGCCCAUU AGCUCAUG
3632
CAUGAGCU CUGAUGAGGCCGUUAGGCCGAA AUGGGCUU
13039





4359
AGCCCAUUA GCUCAUGG
3633
CCAUGAGC CUGAUGAGGCCGUUAGGCCGAA AAUGGGCU
13040





4363
CAUUAGCUC AUGGCUGC
3634
GCAGCCAU CUGAUGAGGCCGUUAGGCCGAA AGCUAAUG
13041





4387
GACCUGCUC UGUCUCUC
3635
GAGAGACA CUGAUGAGGCCGUUAGGCCGAA AGCAGGUC
13042





4391
UGCUCUGUC UCUCUUAU
3636
AUAAGAGA CUGAUGAGGCCGUUAGGCCGAA ACAGAGCA
13043





4393
CUCUGUCUC UCUUAUGG
3637
CCAUAAGA CUGAUGAGGCCGUUAGGCCGAA AGACAGAG
13044





4395
CUGUCUCUC UUAUGGAG
3638
CUCCAUAA CUGAUGAGGCCGUUAGGCCGAA AGAGACAG
13045





4397
GUCUCUCUU AUGGAGGA
3639
UCCUCCAU CUGAUGAGGCCGUUAGGCCGAA AGAGAGAC
13046





4398
UCUCUCUUA UGGAGGAA
3640
UUCCUCCA CUGAUGAGGCCGUUAGGCCGAA AAGAGAGA
13047





4445
AAAAGGCUU UGGGAUGC
3641
GCAUCCCA CUGAUGAGGCCGUUAGGCCGAA AGCCUUUU
13048





4446
AAAGGCUUU GGGAUGCG
3642
CGCAUCCC CUGAUGAGGCCGUUAGGCCGAA AAGCCUUU
13049





4456
GGAUGCGUC CGUCCUGU
3643
ACAGGACG CUGAUGAGGCCGUUAGGCCGAA ACGCAUCC
13050





4460
GCGUCCGUC CUGUGGAG
3644
CUCCACAG CUGAUGAGGCCGUUAGGCCGAA ACGGACGC
13051





4487
AGGGGGCUC CGCUAUGC
3645
GCAUAGCG CUGAUGAGGCCGUUAGGCCGAA AGCCCCCU
13052





4492
GCUCCGCUA UGCCACUU
3646
AAGUGGCA CUGAUGAGGCCGUUAGGCCGAA AGCGGAGC
13053





4500
AUGCCACUU CAGUGACU
3647
AGUCACUG CUGAUGAGGCCGUUAGGCCGAA AGUGGCAU
13054





4501
UGCCACUUC AGUGACUU
3648
AAGUCACU CUGAUGAGGCCGUUAGGCCGAA AAGUGGCA
13055





4509
CAGUGACUU CUCACUCC
3649
GGAGUGAG CUGAUGAGGCCGUUAGGCCGAA AGUCACUG
13056





4510
AGUGACUUC UCACUCCU
3650
AGGAGUGA CUGAUGAGGCCGUUAGGCCGAA AAGUCACU
13057





4512
UGACUUCUC ACUCCUGG
3651
CCAGGAGU CUGAUGAGGCCGUUAGGCCGAA AGAAGUCA
13058





4516
UUCUCACUC CUGGCCUC
3652
GAGGCCAG CUGAUGAGGCCGUUAGGCCGAA AGUGAGAA
13059





4524
CCUGGCCUC CGCUGUUU
3653
AAACAGCG CUGAUGAGGCCGUUAGGCCGAA AGGCCAGG
13060





4531
UCCGCUGUU UCGGGCCC
3654
GGGCCCGA CUGAUGAGGCCGUUAGGCCGAA ACAGCGGA
13061





4532
CCGCUGUUU CGGGCCCC
3655
GGGGCCCG CUGAUGAGGCCGUUAGGCCGAA AACAGCGG
13062





4533
CGCUGUUUC GGGCCCCC
3656
GGGGGCCC CUGAUGAGGCCGUUAGGCCGAA AAACAGCG
13063





4543
GGCCCCCUU CCAAGAGG
3657
CCUCUUGG CUGAUGAGGCCGUUAGGCCGAA AGGGGGCC
13064





4544
GCCCCCUUC CAAGAGGU
3658
ACCUCUUG CUGAUGAGGCCGUUAGGCCGAA AAGGGGGC
13065





4553
CAAGAGGUA UCAGAGCA
3659
UGCUCUGA CUGAUGAGGCCGUUAGGCCGAA ACCUCUUG
13066





4555
AGAGGUAUC AGAGCAGA
3660
UCUGCUCU CUGAUGAGGCCGUUAGGCCGAA AUACCUCU
13067





4577
AGGGACGUU UCCUAGAC
3661
GUCUAGGA CUGAUGAGGCCGUUAGGCCGAA ACGUCCCU
13068





4578
GGGACGUUU CCUAGACC
3662
GGUCUAGG CUGAUGAGGCCGUUAGGCCGAA AACGUCCC
13069





4579
GGACGUUUC CUAGACCA
3663
UGGUCUAG CUGAUGAGGCCGUUAGGCCGAA AAACGUCC
13070





4582
CGUUUCCUA GACCAGGG
3664
CCCUGGUC CUGAUGAGGCCGUUAGGCCGAA AGGAAACG
13071





4598
GCACAUGUU CUCGGGAA
3665
UUCCCGAG CUGAUGAGGCCGUUAGGCCGAA ACAUGUGC
13072





4599
CACAUGUUC UCGGGAAC
3666
GUUCCCGA CUGAUGAGGCCGUUAGGCCGAA AACAUGUG
13073





4601
CAUGUUCUC GGGAACCA
3667
UGGUUCCC CUGAUGAGGCCGUUAGGCCGAA AGAACAUG
13074





4614
ACCACAGUU AAUCUUAA
3668
UUAAGAUU CUGAUGAGGCCGUUAGGCCGAA ACUGUGGU
13075





4615
CCACAGUUA AUCUUAAA
3669
UUUAAGAU CUGAUGAGGCCGUUAGGCCGAA AACUGUGG
13076





4618
CAGUUAAUC UUAAAUCU
3670
AGAUUUAA CUGAUGAGGCCGUUAGGCCGAA AUUAACUG
13077





4620
GUUAAUCUU AAAUCUUU
3671
AAAGAUUU CUGAUGAGGCCGUUAGGCCGAA AGAUUAAC
13078





4621
UUAAUCUUA AAUCUUUU
3672
AAAAGAUU CUGAUGAGGCCGUUAGGCCGAA AAGAUUAA
13079





4625
UCUUAAAUC UUUUCCCG
3673
CGGGAAAA CUGAUGAGGCCGUUAGGCCGAA AUUUAAGA
13080





4627
UUAAAUCUU UUCCCGGG
3674
CCCGGGAA CUGAUGAGGCCGUUAGGCCGAA AGAUUUAA
13081





4628
UAAAUCUUU UCCCGGGA
3675
UCCCGGGA CUGAUGAGGCCGUUAGGCCGAA AAGAUUUA
13082





4629
AAAUCUUUU CCCGGGAG
3676
CUCCCGGG CUGAUGAGGCCGUUAGGCCGAA AAAGAUUU
13083





4630
AAUCUUUUC CCGGGAGU
3677
ACUCCCGG CUGAUGAGGCCGUUAGGCCGAA AAAAGAUU
13084





4639
CCGGGAGUC UUCUGUUG
3678
CAACAGAA CUGAUGAGGCCGUUAGGCCGAA ACUCCCGG
13085





4641
GGGAGUCUU CUGUUGUC
3679
GACAACAG CUGAUGAGGCCGUUAGGCCGAA AGACUCCC
13086





4642
GGAGUCUUC UGUUGUCU
3680
AGACAACA CUGAUGAGGCCGUUAGGCCGAA AAGACUCC
13087





4646
UCUUCUGUU GUCUGUUU
3681
AAACAGAC CUGAUGAGGCCGUUAGGCCGAA ACAGAAGA
13088





4649
UCUGUUGUC UGUUUACC
3682
GGUAAACA CUGAUGAGGCCGUUAGGCCGAA ACAACAGA
13089





4653
UUGUCUGUU UACCAUCC
3683
GGAUGGUA CUGAUGAGGCCGUUAGGCCGAA ACAGACAA
13090





4654
UGUCUGUUU ACCAUCCA
3684
UGGAUGGU CUGAUGAGGCCGUUAGGCCGAA AACAGACA
13092





4655
GUCUGUUUA CCAUCCAA
3685
UUGGAUGG CUGAUGAGGCCGUUAGGCCGAA AAACAGAC
13092





4660
UUUACCAUC CAAAGCAU
3686
AUGCUUUG CUGAUGAGGCCGUUAGGCCGAA AUGGUAAA
13093





4669
CAAAGCAUA UUUAACAU
3687
AUGUUAAA CUGAUGAGGCCGUUAGGCCGAA AUGCUUUG
13094





4671
AAGCAUAUU UAACAUGU
3688
ACAUGUUA CUGAUGAGGCCGUUAGGCCGAA AUAUGCUU
13095





4672
AGCAUAUUU AACAUGUG
3689
CACAUGUU CUGAUGAGGCCGUUAGGCCGAA AAUAUGCU
13096





4673
GCAUAUUUA ACAUGUGU
3690
ACACAUGU CUGAUGAGGCCGUUAGGCCGAA AAAUAUGC
13097





4682
ACAUGUGUC AGUGGGGG
3691
CCCCCACU CUGAUGAGGCCGUUAGGCCGAA ACACAUGU
13098





4698
GUGGCGCUU GGCUUCUG
3692
CAGAAGCC CUGAUGAGGCCGUUAGGCCGAA AGCGCCAC
13099





4703
GCUUGGCUU CUGAGGCC
3693
GGCCUCAG CUGAUGAGGCCGUUAGGCCGAA AGCCAAGC
13100





4704
CUUGGCUUC UGAGGCCA
3694
UGGCCUCA CUGAUGAGGCCGUUAGGCCGAA AAGCCAAG
13101





4720
AGAGCCAUC AUCAGUUC
3695
GAACUGAU CUGAUGAGGCCGUUAGGCCGAA AUGGCUCU
13102





4723
GCCAUCAUC AGUUCCUC
3696
GAGGAACU CUGAUGAGGCCGUUAGGCCGAA AUGAUGGC
13103





4727
UCAUCAGUU CCUCUAGU
3697
ACUAGAGG CUGAUGAGGCCGUUAGGCCGAA ACUGAUGA
13104





4728
CAUCAGUUC CUCUAGUG
3698
CACUAGAG CUGAUGAGGCCGUUAGGCCGAA AACUGAUG
13105





4731
CAGUUCCUC UAGUGAGA
3699
UCUCACUA CUGAUGAGGCCGUUAGGCCGAA AGGAACUG
13106





4733
GUUCCUCUA GUGAGAUG
3700
CAUCUCAC CUGAUGAGGCCGUUAGGCCGAA AGAGGAAC
13107





4745
AGAUGCAUU GAGGUCAU
3701
AUGACCUC CUGAUGAGGCCGUUAGGCCGAA AUGCAUCU
13108





4751
AUUGAGGUC AUACCCAA
3702
UUGGGUAU CUGAUGAGGCCGUUAGGCCGAA ACCUCAAU
13109





4754
GAGGUCAUA CCCAAGCU
3703
AGCUUGGG CUGAUGAGGCCGUUAGGCCGAA AUGACCUC
13110





4763
CCCAAGCUU GCAGGCCU
3704
AGGCCUGC CUGAUGAGGCCGUUAGGCCGAA AGCUUGGG
13111





4777
CCUGACCUU CGCAUACU
3705
AGUAUGCG CUGAUGAGGCCGUUAGGCCGAA AGGUCAGG
13112





4778
CUGACCUUC GCAUACUG
3706
CAGUAUGC CUGAUGAGGCCGUUAGGCCGAA AAGGUCAG
13113





4783
CUUCGCAUA CUGCUCAC
3707
GUGAGCAG CUGAUGAGGCCGUUAGGCCGAA AUGCGAAG
13114





4789
AUACUGCUC ACGGGGAG
3708
CUCCCCGU CUGAUGAGGCCGUUAGGCCGAA AGCAGUAU
13115





4799
CGGGGAGUU AAGUGGUC
3709
GACCACUU CUGAUGAGGCCGUUAGGCCGAA ACUCCCCG
13116





4800
GGGGAGUUA AGUGGUCC
3710
GGACCACU CUGAUGAGGCCGUUAGGCCGAA AACUCCCC
13117





4807
UAAGUGGUC CAGUUUGG
3711
CCAAACUG CUGAUGAGGCCGUUAGGCCGAA ACCACUUA
13118





4812
GGUCCAGUU UGGCCUAG
3712
CUAGGCCA CUGAUGAGGCCGUUAGGCCGAA ACUGGACC
13119





4813
GUCCAGUUU GGCCUAGU
3713
ACUAGGCC CUGAUGAGGCCGUUAGGCCGAA AACUGGAC
13120





4819
UUUGGCCUA GUAAGGUU
3714
AACCUUAC CUGAUGAGGCCGUUAGGCCGAA AGGCCAAA
13121





4822
GGCCUAGUA AGGUUGCC
3715
GGCAACCU CUGAUGAGGCCGUUAGGCCGAA ACUAGGCC
13122





4827
AGUAAGGUU GCCUACUG
3716
CAGUAGGC CUGAUGAGGCCGUUAGGCCGAA ACCUUACU
13123





4832
GGUUGCCUA CUGAUGGG
3717
CCCAUCAG CUGAUGAGGCCGUUAGGCCGAA AGGCAACC
13124





4843
GAUGGGCUC AAAAGCCA
3718
UGGCUUUU CUGAUGAGGCCGUUAGGCCGAA AGCCCAUC
13125





4855
AGCCACAUU UUAAACAG
3719
CUGUUUAA CUGAUGAGGCCGUUAGGCCGAA AUGUGGCU
13126





4855
GCCACAUUU UAAACAGG
3720
CCUGUUUA CUGAUGAGGCCGUUAGGCCGAA AAUGUGGC
13127





4857
CCACAUUUU AAACAGGU
3721
ACCUGUUU CUGAUGAGGCCGUUAGGCCGAA AAAUGUGG
13128





4858
CACAUUUUA AACAGGUU
3722
AACCUGUU CUGAUGAGGCCGUUAGGCCGAA AAAAUGUG
13129





4866
AAACAGGUU UUAUCUCA
3723
UGAGAUAA CUGAUGAGGCCGUUAGGCCGAA ACCUGUUU
13130





4867
AACAGGUUU UAUCUCAA
3724
UUGAGAUA CUGAUGAGGCCGUUAGGCCGAA AACCUGUU
13131





4868
ACAGGUUUU AUCUCAAG
3725
CUUGAGAU CUGAUGAGGCCGUUAGGCCGAA AAACCUGU
13132





4869
CAGGUUUUA UCUCAAGU
3726
ACUUGAGA CUGAUGAGGCCGUUAGGCCGAA AAAACCUG
13133





4871
GGUUUUAUC UCAAGUAU
3727
AUACUUGA CUGAUGAGGCCGUUAGGCCGAA AUAAAACC
13134





4873
UUUUAUCUC AAGUAUUA
3728
UAAUACUU CUGAUGAGGCCGUUAGGCCGAA AGAUAAAA
13135





4878
UCUCAAGUA UUAAUAUA
3729
UAUAUUAA CUGAUGAGGCCGUUAGGCCGAA ACUUGAGA
13136





4880
UCAAGUAUU AAUAUAUA
3730
UAUAUAUU CUGAUGAGGCCGUUAGGCCGAA AUACUUGA
13137





4881
CAAGUAUUA AUAUAUAG
3731
CUAUAUAU CUGAUGAGGCCGUUAGGCCGAA AAUACUUG
13138





4884
GUAUUAAUA UAUAGACA
3732
UGUCUAUA CUGAUGAGGCCGUUAGGCCGAA AUUAAUAC
13139





4886
AUUAAUAUA UAGACAAG
3733
CUUGUCUA CUGAUGAGGCCGUUAGGCCGAA AUAUUAAU
13140





4888
UAAUAUAUA GACAAGAC
3734
GUCUUGUC CUGAUGAGGCCGUUAGGCCGAA AUAUAUUA
13141





4900
AAGACACUU AUGCAUUA
3735
UAAUGCAU CUGAUGAGGCCGUUAGGCCGAA AGUGUCUU
13142





4901
AGACACUUA UGCAUUAU
3736
AUAAUGCA CUGAUGAGGCCGUUAGGCCGAA AAGUGUCU
13143





4907
UUAUGCAUU AUCCUGUU
3737
AACAGGAU CUGAUGAGGCCGUUAGGCCGAA AUGCAUAA
13144





4908
UAUGCAUUA UCCUGUUU
3738
AAACAGGA CUGAUGAGGCCGUUAGGCCGAA AAUGCAUA
13145





4910
UGCAUUAUC CUGUUUUA
3739
UAAAACAG CUGAUGAGGCCGUUAGGCCGAA AUAAUGCA
13146





4915
UAUCCUGUU UUAUAUAU
3740
AUAUAUAA CUGAUGAGGCCGUUAGGCCGAA ACAGGAUA
13147





4916
AUCCUGUUU UAUAUAUC
3741
GAUAUAUA CUGAUGAGGCCGUUAGGCCGAA AACAGGAU
13148





4917
UCCUGUUUU AUAUAUCC
3742
GGAUAUAU CUGAUGAGGCCGUUAGGCCGAA AAACAGGA
13149





4918
CCUGUUUUA UAUAUCCA
3743
UGGAUAUA CUGAUGAGGCCGUUAGGCCGAA AAAACAGG
13150





4920
UGUUUUAUA UAUCCAAU
3744
AUUGGAUA CUGAUGAGGCCGUUAGGCCGAA AUAAAACA
13151





4922
UUUUAUAUA UCCAAUGA
3745
UCAUUGGA CUGAUGAGGCCGUUAGGCCGAA AUAUAAAA
13152





4924
UUAUAUAUC CAAUGAAU
3746
AUUCAUUG CUGAUGAGGCCGUUAGGCCGAA AUAUAUAA
13153





4933
CAAUGAAUA UAACUGGG
3747
CCCAGUUA CUGAUGAGGCCGUUAGGCCGAA AUUCAUUG
13154





4935
AUGAAUAUA ACUGGGGC
3748
GCCCCAGU CUGAUGAGGCCGUUAGGCCGAA AUAUUCAU
13155





4948
GGGCGAGUU AAGAGUCA
3749
UGACUCUU CUGAUGAGGCCGUUAGGCCGAA ACUCGCCC
13156





4949
GGCGAGUUA AGAGUCAU
3750
AUGACUCU CUGAUGAGGCCGUUAGGCCGAA AACUCGCC
13157





4955
UUAAGAGUC AUGGUCUA
3751
UAGACCAU CUGAUGAGGCCGUUAGGCCGAA ACUCUUAA
13158





4961
GUCAUGGUC UAGAAAAG
3752
CUUUUCUA CUGAUGAGGCCGUUAGGCCGAA ACCAUGAC
13159





4963
CAUGGUCUA GAAAAGGG
3753
CCCUUUUC CUGAUGAGGCCGUUAGGCCGAA AGACCAUG
13160





4974
AAAGGGGUU UCUCUGUA
3754
UACAGAGA CUGAUGAGGCCGUUAGGCCGAA ACCCCUUU
13161





4975
AAGGGGUUU CUCUGUAC
3755
GUACAGAG CUGAUGAGGCCGUUAGGCCGAA AACCCCUU
13162





4976
AGGGGUUUC UCUGUACC
3756
GGUACAGA CUGAUGAGGCCGUUAGGCCGAA AAACCCCU
13163





4978
GGGUUUCUC UGUACCCA
3757
UGGGUACA CUGAUGAGGCCGUUAGGCCGAA AGAAACCC
13164





4982
UUCUCUGUA CCCAAAUC
3758
GAUUUGGG CUGAUGAGGCCGUUAGGCCGAA ACAGAGAA
13165





4990
ACCCAAAUC GGGCUGGU
3759
ACCAGCCC CUGAUGAGGCCGUUAGGCCGAA AUUUGGGU
13166





4999
GGGCUGGUU GGACCAAG
3760
CUUGGUCC CUGAUGAGGCCGUUAGGCCGAA ACCAGCCC
13167





5029
AGAGUGGUU GUCCCAGC
3761
GCUGGGAC CUGAUGAGGCCGUUAGGCCGAA ACCACUCU
13168





5032
GUGGUUGUC CCAGCUAU
3762
AUAGCUGG CUGAUGAGGCCGUUAGGCCGAA ACAACCAC
13169





5039
UCCCAGCUA UAGUUACU
3763
AGUAACUA CUGAUGAGGCCGUUAGGCCGAA AGCUGGGA
13170





5041
CCAGCUAUA GUUACUAA
3764
UUAGUAAC CUGAUGAGGCCGUUAGGCCGAA AUAGCUGG
13171





5044
GCUAUAGUU ACUAAACU
3765
AGUUUAGU CUGAUGAGGCCGUUAGGCCGAA ACUAUAGC
13172





5045
CUAUAGUUA CUAAACUA
3766
UAGUUUAG CUGAUGAGGCCGUUAGGCCGAA AACUAUAG
13173





5048
UAGUUACUA AACUACUC
3767
GAGUAGUU CUGAUGAGGCCGUUAGGCCGAA AGUAACUA
13174





5053
ACUAAACUA CUCACCCA
3768
UGGGUGAG CUGAUGAGGCCGUUAGGCCGAA AGUUUAGU
13175





5056
AAACUACUC ACCCAAAG
3769
CUUUGGGU CUGAUGAGGCCGUUAGGCCGAA AGUAGUUU
13176





5066
CCCAAAGUU GGGACCUC
3770
GAGGUCCC CUGAUGAGGCCGUUAGGCCGAA ACUUUGGG
13177





5074
UGGGACCUC ACUGGCUU
3771
AAGCCAGU CUGAUGAGGCCGUUAGGCCGAA AGGUCCCA
13178





5082
CACUGGCUU CUCUUUAC
3772
GUAAAGAG CUGAUGAGGCCGUUAGGCCGAA AGCCAGUG
13179





5083
ACUGGCUUC UCUUUACU
3773
AGUAAAGA CUGAUGAGGCCGUUAGGCCGAA AAGCCAGU
13180





5085
UGGCUUCUC UUUACUUC
3774
GAAGUAAA CUGAUGAGGCCGUUAGGCCGAA AGAAGCCA
13181





5087
GCUUCUCUU UACUUCAU
3775
AUGAAGUA CUGAUGAGGCCGUUAGGCCGAA AGAGAAGC
13182





5088
CUUCUCUUU ACUUCAUC
3776
GAUGAAGU CUGAUGAGGCCGUUAGGCCGAA AAGAGAAG
13183





5089
UUCUCUUUA CUUCAUCA
3777
UGAUGAAG CUGAUGAGGCCGUUAGGCCGAA AAAGAGAA
13184





5092
UCUUUACUU CAUCAUGG
3778
CCAUGAUG CUGAUGAGGCCGUUAGGCCGAA AGUAAAGA
13185





5093
CUUUACUUC AUCAUGGA
3779
UCCAUGAU CUGAUGAGGCCGUUAGGCCGAA AAGUAAAG
13186





5096
UACUUCAUC AUGGAUUU
3780
AAAUCCAU CUGAUGAGGCCGUUAGGCCGAA AUGAAGUA
13187





5103
UCAUGGAUU UCACCAUC
3781
GAUGGUGA CUGAUGAGGCCGUUAGGCCGAA AUCCAUGA
13188





5104
CAUGGAUUU CACCAUCC
3782
GGAUGGUG CUGAUGAGGCCGUUAGGCCGAA AAUCCAUG
13189





5105
AUGGAUUUC ACCAUCCC
3783
GGGAUGGU CUGAUGAGGCCGUUAGGCCGAA AAAUCCAU
13190





5111
UUCACCAUC CCAAGGCA
3784
UGCCUUGG CUGAUGAGGCCGUUAGGCCGAA AUGGUGAA
13191





5122
AAGGCAGUC UGAGAGGA
3785
UCCUCUCA CUGAUGAGGCCGUUAGGCCGAA ACUGCCUU
13192





5134
GAGGAGCUA AAGAGUAU
3786
AUACUCUU CUGAUGAGGCCGUUAGGCCGAA AGCUCCUC
13193





5141
UAAAGAGUA UCAGCCCA
3787
UGGGCUGA CUGAUGAGGCCGUUAGGCCGAA ACUCUUUA
13194





5143
AAGAGUAUC AGCCCAUA
3788
UAUGGGCU CUGAUGAGGCCGUUAGGCCGAA AUACUCUU
13195





5151
CAGCCCAUA UUUAUUAA
3789
UUAAUAAA CUGAUGAGGCCGUUAGGCCGAA AUGGGCUG
13196





5153
GCCCAUAUU UAUUAAGC
3790
GCUUAAUA CUGAUGAGGCCGUUAGGCCGAA AUAUGGGC
13197





5154
CCCAUAUUU AUUAAGCA
3791
UGCUUAAU CUGAUGAGGCCGUUAGGCCGAA AAUAUGGG
13198





5155
CCAUAUUUA UUAAGCAC
3792
GUGCUUAA CUGAUGAGGCCGUUAGGCCGAA AAAUAUGG
13199





5157
AUAUUUAUU AAGCACUU
3793
AAGUGCUU CUGAUGAGGCCGUUAGGCCGAA AUAAAUAU
13200





5158
UAUUUAUUA AGCACUUU
3794
AAAGUGCU CUGAUGAGGCCGUUAGGCCGAA AAUAAAUA
13201





5165
UAAGCACUU UAUGCUCC
3795
GGAGCAUA CUGAUGAGGCCGUUAGGCCGAA AGUGCUUA
13202





5166
AAGCACUUU AUGCUCCU
3796
AGGAGCAU CUGAUGAGGCCGUUAGGCCGAA AAGUGCUU
13203





5167
AGCACUUUA UGCUCCUU
3797
AAGGAGCA CUGAUGAGGCCGUUAGGCCGAA AAAGUGCU
13204





5172
UUUAUGCUC CUUGGCAC
3798
GUGCCAAG CUGAUGAGGCCGUUAGGCCGAA AGCAUAAA
13205





5175
AUGCUCCUU GGCACAGC
3799
GCUGUGCC CUGAUGAGGCCGUUAGGCCGAA AGGAGCAU
13206





5195
UGAUGUGUA AUUUAUGC
3800
GCAUAAAU CUGAUGAGGCCGUUAGGCCGAA ACACAUCA
13207





5198
UGUGUAAUU UAUGCAAG
3801
CUUGCAUA CUGAUGAGGCCGUUAGGCCGAA AUUACACA
13208





5199
GUGUAAUUU AUGCAAGC
3802
GCUUGCAU CUGAUGAGGCCGUUAGGCCGAA AAUUACAC
13209





5200
UGUAAUUUA UGCAAGCU
3803
AGCUUGCA CUGAUGAGGCCGUUAGGCCGAA AAAUUACA
13210





5209
UGCAAGCUC CCUCUCCA
3804
UGGAGAGG CUGAUGAGGCCGUUAGGCCGAA AGCUUGCA
13211





5213
AGCUCCCUC UCCAGCUA
3805
UAGCUGGA CUGAUGAGGCCGUUAGGCCGAA AGGGAGCU
13212





5215
CUCCCUCUC CAGCUAGG
3806
CCUAGCUG CUGAUGAGGCCGUUAGGCCGAA AGAGGGAG
13213





5221
CUCCAGCUA GGACUCAG
3807
CUGAGUCC CUGAUGAGGCCGUUAGGCCGAA AGCUGGAG
13214





5227
CUAGGACUC AGGAUAUU
3808
AAUAUCCU CUGAUGAGGCCGUUAGGCCGAA AGUCCUAG
13215





5233
CUCAGGAUA UUAGUCAA
3809
UUGACUAA CUGAUGAGGCCGUUAGGCCGAA AUCCUGAG
13216





5235
CAGGAUAUU AGUCAAUG
3810
CAUUGACU CUGAUGAGGCCGUUAGGCCGAA AUAUCCUG
13217





5236
AGGAUAUUA GUCAAUGA
3811
UCAUUGAC CUGAUGAGGCCGUUAGGCCGAA AAUAUCCU
13218





5239
AUAUUAGUC AAUGAGCC
3812
GGCUCAUU CUGAUGAGGCCGUUAGGCCGAA ACUAAUAU
10358





5250
UGAGCCAUC AAAAGGAA
3813
UUCCUUUU CUGAUGAGGCCGUUAGGCCGAA AUGGCUCA
13219





5273
AAAAACCUA UCUUAUUU
3814
AAAUAAGA CUGAUGAGGCCGUUAGGCCGAA AGGUUUUU
13220





5275
AAACCUAUC UUAUUUUC
3815
GAAAAUAA CUGAUGAGGCCGUUAGGCCGAA AUAGGUUU
13221





5277
ACCUAUCUU AUUUUCAU
3816
AUGAAAAU CUGAUGAGGCCGUUAGGCCGAA AGAUAGGU
13222





5278
CCUAUCUUA UUUUCAUC
3817
GAUGAAAA CUGAUGAGGCCGUUAGGCCGAA AAGAUAGG
13223





5280
UAUCUUAUU UUCAUCUG
3818
CAGAUGAA CUGAUGAGGCCGUUAGGCCGAA AUAAGAUA
13224





5281
AUCUUAUUU UCAUCUGU
3819
ACAGAUGA CUGAUGAGGCCGUUAGGCCGAA AAUAAGAU
13225





5282
UCUGAUGUG CAUCUGUG
3820
AACAGAUG CUGAUGAGGCCGUUAGGCCGAA AAAUAAGA
13226





5283
CUUAUUUUC AUCUGUUU
3821
AAACAGAU CUGAUGAGGCCGUUAGGCCGAA AAAAUAAG
13227





5286
AUGGUCAUC UGUUUCAU
3822
AUGAAACA CUGAUGAGGCCGUUAGGCCGAA AUGAAAAU
13228





5290
UCAUCUGUU UCAUACCU
3823
AGGUAUGA CUGAUGAGGCCGUUAGGCCGAA ACAGAUGA
13229





5291
CAUCUGUUU CAUACCUU
3824
AAGGUAUG CUGAUGAGGCCGUUAGGCCGAA AACAGAUG
13230





5292
AUCUGUGUC AUACCUUG
3825
CAAGGUAU CUGAUGAGGCCGUUAGGCCGAA AAACAGAU
13231





5295
UGUUUCAUA CCUUGUCU
3826
AGACAAGG CUGAUGAGGCCGUUAGGCCGAA AUGAAACA
13232





5299
UCAUACCUU GUCUGGGG
3827
CCCCAGAC CUGAUGAGGCCGUUAGGCCGAA AGGUAGGA
13233





5302
UACCUUGUC UGGGGUCU
3828
AGACCCCA CUGAUGAGGCCGUUAGGCCGAA ACAAGGUA
13234





5309
UCUGGGGUC UAAUGACG
3829
CGUCAUUA CUGAUGAGGCCGUUAGGCCGAA ACCCCAGA
13235





5311
UGGGGUCUA AUGACGAU
3830
AUCGUCAU CUGAUGAGGCCGUUAGGCCGAA AGACCCCA
13236





5331
AACAGGGUA GACAUGGG
3831
CCCAUGUC CUGAUGAGGCCGUUAGGCCGAA ACCCUGUU
13237





5350
GACAGGGUA GAAAAGGG
3832
CCCUUUUC CUGAUGAGGCCGUUAGGCCGAA ACCCUGUC
13238





5367
UGCCCGCUC UUUGGGGU
3833
ACCCCAAA CUGAUGAGGCCGUUAGGCCGAA AGCGGGCA
13239





5369
CCCGCUCUU UGGGGUCU
3834
AGACCCCA CUGAUGAGGCCGUUAGGCCGAA AGAGCGGG
13240





5370
CCGCUCUUU GGGGUCUA
3835
UAGACCCC CUGAUGAGGCCGUUAGGCCGAA AAGAGCGG
13241





5376
UUUGGGGUC UAGAGAUG
3836
CAUCUCUA CUGAUGAGGCCGUUAGGCCGAA ACCCCAAA
13242





5378
UGGGGUCUA GAGAUGAG
3837
CUCAUCUC CUGAUGAGGCCGUUAGGCCGAA AGACCCCA
13243





5395
CCCUGGGUC UCUAAAAU
3838
AUUUUAGA CUGAUGAGGCCGUUAGGCCGAA ACCCAGGG
13244





5397
CUGGGUCUC UAAAAUGG
3839
CCAUUUUA CUGAUGAGGCCGUUAGGCCGAA AGACCCAG
13245





5399
GGGUCUCUA AAAUGGCU
3840
AGCCAUUU CUGAUGAGGCCGUUAGGCCGAA AGAGACCC
13246





5408
AAAUGGCUC UCUUAGAA
3841
UUCUAAGA CUGAUGAGGCCGUUAGGCCGAA AGCCAUUU
13247





5410
AUGGCUCUC UUAGAAGU
3842
ACUUCUAA CUGAUGAGGCCGUUAGGCCGAA AGAGCCAU
13248





5412
GGCUCUCUU AGAAGUUG
3843
CAACUUCU CUGAUGAGGCCGUUAGGCCGAA AGAGAGCC
13249





5413
GCUCUCUUA GAAGUUGU
3844
ACAACUGC CUGAUGAGGCCGUUAGGCCGAA AAGAGAGC
13250





5419
UUAGAAGUU GUAUGUGC
3845
GCACAUAC CUGAUGAGGCCGUUAGGCCGAA ACUUCUAA
13251





5422
GAAGUUGUA UGUGCAAA
3846
UUUGCACA CUGAUGAGGCCGUUAGGCCGAA ACAACUUC
13252





5432
GUGCAAAUU AUGGUCUG
3847
CAGACCAG CUGAUGAGGCCGUUAGGCCGAA AUUUGCAC
13253





5433
UGCAAAUUA UGGUCUGU
3848
ACAGACCA CUGAUGAGGCCGUUAGGCCGAA AAUUUGCA
13254





5438
AUUAUGGUC UGUGUGCU
3849
AGCACACA CUGAUGAGGCCGUUAGGCCGAA ACCAUAAU
13255





5447
UGUGUGCUU AGGUCGUG
3850
CACGACCU CUGAUGAGGCCGUUAGGCCGAA AGCACACA
13256





5448
GUGUGCUUA GGUCGUGC
3851
GCACGACC CUGAUGAGGCCGUUAGGCCGAA AAGCACAC
13257





5452
GCUUAGGUC GUGCACAC
3852
GUGUGCAC CUGAUGAGGCCGUUAGGCCGAA ACCUAAGC
13258





5475
GAGCCGGUC ACAGCUGG
3853
CCAGCUGU CUGAUGAGGCCGUUAGGCCGAA ACCGGCUC
13259





5497
CGAUGAAUA GCUGCUUU
3854
AAAGCAGC CUGAUGAGGCCGUUAGGCCGAA AUUCAUCG
13260





5504
UAGCUGCUU UGGGAGAG
3855
CUCUCCCA CUGAUGAGGCCGUUAGGCCGAA AGCAGCUA
13261





5505
AGCUGCUUU GGGAGAGC
3856
GCUCUCCC CUGAUGAGGCCGUUAGGCCGAA AAGCAGCU
13262





5524
AGCAUGCUA GCCACUUA
3857
UAAGUGGC CUGAUGAGGCCGUUAGGCCGAA AGCAUGCU
13263





5531
UAGCCACUU AAUUCUCU
3858
AGAGAAUU CUGAUGAGGCCGUUAGGCCGAA AGUGGCUA
13264





5532
AGCCACUUA AUUCUCUG
3859
CAGAGAAU CUGAUGAGGCCGUUAGGCCGAA AAGUGGCU
13265





5535
CACUUAAUU CUCUGACC
3860
GGUCAGAG CUGAUGAGGCCGUUAGGCCGAA AUUAAGUG
13266





5536
ACUUAAUUC UCUGACCG
3861
CGGUCAGA CUGAUGAGGCCGUUAGGCCGAA AAUUAAGU
13267





5538
UUAAUUCUC UGACCGGG
3862
CCCGGUCA CUGAUGAGGCCGUUAGGCCGAA AGAAUUAA
13268





5554
GCCAGCAUC AUGGGUAC
3863
GUACCCAU CUGAUGAGGCCGUUAGGCCGAA AUGCUGGC
13269





5561
UCAUGGGUA CCUGCUCC
3864
GGAGCAGG CUGAUGAGGCCGUUAGGCCGAA ACCCAUGA
13270





5568
UACCUGCUC CCCUGUGU
3865
ACACAGGG CUGAUGAGGCCGUUAGGCCGAA AGCAGGUA
13271





5577
CCCUGUGUA CCCCAUCC
3866
GGAUGGGG CUGAUGAGGCCGUUAGGCCGAA ACACAGGG
13272





5584
UACCCCAUC CUUAAGGU
3867
ACCUUAAG CUGAUGAGGCCGUUAGGCCGAA AUGGGGUA
13273





5587
CCCAUCCUU AAGGUUUU
3868
AAAACCUU CUGAUGAGGCCGUUAGGCCGAA AGGAUGGG
13274





5588
CCAUCCUUA AGGUUUUC
3869
GAAAACCU CUGAUGAGGCCGUUAGGCCGAA AAGGAUGG
13275





5593
CUUAAGGUU UUCUGUCU
3870
AGACAGAA CUGAUGAGGCCGUUAGGCCGAA ACCUUAAG
13276





5594
UUAAGGUUU UCUGUCUG
3871
CAGACAGA CUGAUGAGGCCGUUAGGCCGAA AACCUUAA
13277





5595
UAAGGUUUU CUGUCUGA
3872
UCAGACAG CUGAUGAGGCCGUUAGGCCGAA AAACCUUA
13278





5596
AAGGUUUUC UGUCUGAU
3873
AUCAGACA CUGAUGAGGCCGUUAGGCCGAA AAAACCUU
13279





5600
UUUUCUGUC UGAUGAGA
3874
UCUCAUCA CUGAUGAGGCCGUUAGGCCGAA ACAGAAAA
13280





5627
AGUGCAAUC CCCACUGA
3875
UCAGUGGG CUGAUGAGGCCGUUAGGCCGAA AUUGCACU
13281





5660
CUGUGGCUC UUGGUGCA
3876
UGCACCAA CUGAUGAGGCCGUUAGGCCGAA AGCCACAG
13282





5662
GUGGCUCUU GGUGCACU
3877
AGUGCACC CUGAUGAGGCCGUUAGGCCGAA AGAGCCAC
13283





5671
GGUGCACUC ACCAGCCA
3878
UGGCUGGU CUGAUGAGGCCGUUAGGCCGAA AGUGCACC
13284





5685
CCAGGACUA GACAAGUA
3879
UACUUGUC CUGAUGAGGCCGUUAGGCCGAA AGUCCUGG
13285





5693
AGACAAGUA GGAAAGGG
3880
CCCUUUCC CUGAUGAGGCCGUUAGGCCGAA ACUUGUCU
13286





5704
AAAGGGCUU CUAGCCAC
3881
GUGGCUAG CUGAUGAGGCCGUUAGGCCGAA AGCCCUUU
13287





5705
AAGGGCUUC UAGCCACA
3882
UGUGGCUA CUGAUGAGGCCGUUAGGCCGAA AAGCCCUU
13288





5707
GGGCUUCUA GCCACACU
3883
AGUGUGGC CUGAUGAGGCCGUUAGGCCGAA AGAAGCCC
13289





5731
AAGAAAAUC AGGUAGGG
3884
CCCUACCU CUGAUGAGGCCGUUAGGCCGAA AUUUUCUU
13290





5736
AAUCAGGUA GGGCUGGC
3885
GCCAGCCC CUGAUGAGGCCGUUAGGCCGAA ACCUGAUU
13291





5754
AAAGACAUC UUUGUCCA
3886
UGGACAAA CUGAUGAGGCCGUUAGGCCGAA AUGUCUUU
13292





5756
AGACAUCUU UGUCCAUU
3887
AAUGGACA CUGAUGAGGCCGUUAGGCCGAA AGAUGUCU
13293





5757
GACAUCUUU GUCCAUUC
3888
GAAUGGAC CUGAUGAGGCCGUUAGGCCGAA AAGAUGUC
13294





5760
AUCUUUGUC CAUUCGCA
3889
UGCGAAUG CUGAUGAGGCCGUUAGGCCGAA ACAAAGAU
13295





5764
UUGUCCAUU CGCAAAAG
3890
CUUUUGCG CUGAUGAGGCCGUUAGGCCGAA AUGGACAA
13296





5765
UGUCCAUUC GCAAAAGC
3891
GCUUUUGC CUGAUGAGGCCGUUAGGCCGAA AAUGGACA
13297





5775
CAAAAGCUC UUGUCGGC
3892
GCCGACAA CUGAUGAGGCCGUUAGGCCGAA AGCUUUUG
13298





5777
AAAGCUCUU GUCGGCUG
3893
CAGCCGAC CUGAUGAGGCCGUUAGGCCGAA AGAGCUUU
13299





5780
GCUCUUGUC GGCUGCAG
3894
CUGCAGCC CUGAUGAGGCCGUUAGGCCGAA ACAAGAGC
13300





5794
CAGUGUGUA AGUCAGGC
3895
GCCUGACU CUGAUGAGGCCGUUAGGCCGAA ACACACUG
13301





5798
GUGUAAGUC AGGCGAUG
3896
CAUCGCCU CUGAUGAGGCCGUUAGGCCGAA ACUUACAC
13302





5818
CAGAGGCUA CCAGAGAA
3897
UUCUCUGG CUGAUGAGGCCGUUAGGCCGAA AGCCUCUG
13303





5852
CCUGAGGUU UCUCAUCC
3898
GGAUGAGA CUGAUGAGGCCGUUAGGCCGAA ACCUCAGG
13304





5853
CUGAGGUUU CUCAUCCA
3899
UGGAUGAG CUGAUGAGGCCGUUAGGCCGAA AACCUCAG
13305





5854
UGAGGUUUC UCAUCCAG
3900
CUGGAUGA CUGAUGAGGCCGUUAGGCCGAA AAACCUCA
13306





5856
AGGUUUCUC AUCCAGAU
3901
AUCUGGAU CUGAUGAGGCCGUUAGGCCGAA AGAAACCU
13307





5859
UUUCUCAUC CAGAUAUC
3902
GAUAUCUG CUGAUGAGGCCGUUAGGCCGAA AUGAGAAA
13308





5865
AUCCAGAUA UCCAGCAA
3903
UUGCUGGA CUGAUGAGGCCGUUAGGCCGAA AUCUGGAU
13309





5867
CCAGAUAUC CAGCAAUU
3904
AAUUGCUG CUGAUGAGGCCGUUAGGCCGAA AUAUCUGG
13310





5875
CCAGCAAUU GGGGGGUG
3905
CACCCCCC CUGAUGAGGCCGUUAGGCCGAA AUUGCUGG
13311





5896
AAGACCAUA GAUGGUCC
3906
GGACCAUC CUGAUGAGGCCGUUAGGCCGAA AUGGUCUU
13312





5903
UAGAUGGUC CUGUAUUA
3907
UAAUACAG CUGAUGAGGCCGUUAGGCCGAA ACCAUCUA
13313





5908
GGUCCUGUA UUAUUCCG
3908
CGGAAUAA CUGAUGAGGCCGUUAGGCCGAA ACAGGACC
13314





5910
UCCUGUAUU AUUCCGAU
3909
AUCGGAAU CUGAUGAGGCCGUUAGGCCGAA AUACAGGA
13315





5911
CCUGUAUUA UUCCGAUU
3910
AAUCGGAA CUGAUGAGGCCGUUAGGCCGAA AAUACAGG
13316





5913
UGUAUUAUU CCGAUUUU
3911
AAAAUCGG CUGAUGAGGCCGUUAGGCCGAA AUAAUACA
13317





5914
GUAUUAUUC CGAUUUUA
3912
UAAAAUCG CUGAUGAGGCCGUUAGGCCGAA AAUAAUAC
13318





5919
AUUCCGAUU UUAAUAAU
3913
AUUAUUAA CUGAUGAGGCCGUUAGGCCGAA AUCGGAAU
13319





5920
UUCCGAUUU UAAUAAUC
3914
GAUUAUUA CUGAUGAGGCCGUUAGGCCGAA AAUCGGAA
13320





5921
UCCGAUUUU AAUAAUCU
3915
AGAUUAUU CUGAUGAGGCCGUUAGGCCGAA AAAUCGGA
13321





5922
CCGAUUUUA AUAAUCUA
3916
UAGAUUAU CUGAUGAGGCCGUUAGGCCGAA AAAAUCGG
13322





5925
AUUUUAAUA AUCUAAUU
3917
AAUUAGAU CUGAUGAGGCCGUUAGGCCGAA AUUAAAAU
13323





5928
UUAAUAAUC UAAUUCGU
3918
ACGAAUUA CUGAUGAGGCCGUUAGGCCGAA AUUAUUAA
13324





5930
AAUAAUCUA AUUCGUGA
3919
UCACGAAU CUGAUGAGGCCGUUAGGCCGAA AGAUUAUU
13325





5933
AAUCUAAUU CGUGAUCA
3920
UGAUCACG CUGAUGAGGCCGUUAGGCCGAA AUUAGAUU
13326





5934
AUCUAAUUC GUGAUCAU
3921
AUGAUCAC CUGAUGAGGCCGUUAGGCCGAA AAUUAGAU
13327





5940
UUCGUGAUC AUUAAGAG
3922
CUCUUAAU CUGAUGAGGCCGUUAGGCCGAA AUCACGAA
13328





5943
GUGAUCAUU AAGAGACU
3923
AGUCUCUU CUGAUGAGGCCGUUAGGCCGAA AUGAUCAC
13329





5944
UGAUCAUGA AGAGACUU
3924
AAGUCUCU CUGAUGAGGCCGUUAGGCCGAA AAUGAUCA
13330





5952
AAGAGACUU UAGUAAAU
3925
AUUUACUA CUGAUGAGGCCGUUAGGCCGAA AGUCUCUU
13331





5953
AGAGACUUU AGUAAAUG
3926
CAUUUACU CUGAUGAGGCCGUUAGGCCGAA AAGUCUCU
13332





5954
GAGACUUUA GUAAAUGU
3927
ACAUUUAC CUGAUGAGGCCGUUAGGCCGAA AAAGUCUC
13333





5957
ACUUUAGUA AAUGUCCC
3928
GGGACAUU CUGAUGAGGCCGUUAGGCCGAA ACUAAAGU
13334





5963
GUAAAUGUC CCUUUUCC
3929
GGAAAAGG CUGAUGAGGCCGUUAGGCCGAA ACAUUUAC
13335





5967
AUGUCCCUU UUCCCACA
3930
UGUGGGAA CUGAUGAGGCCGUUAGGCCGAA AGGGACAU
13336





5968
UGUCCCUUU UCCCACAA
3931
UUGUGGGA CUGAUGAGGCCGUUAGGCCGAA AAGGGACA
13337





5969
GUCCCUUUU CCCACAAA
3932
UUUGUGGG CUGAUGAGGCCGUUAGGCCGAA AAAGGGAC
13338





5970
UCCCUUUUC CCACAAAA
3933
UUUUGUGG CUGAUGAGGCCGUUAGGCCGAA AAAAGGGA
13339





5981
ACAAAAGUA AAGAAAAG
3934
CUUUUCUU CUGAUGAGGCCGUUAGGCCGAA ACUUUUGU
13340





5992
GAAAAGCUA UCGGGAUU
3935
AAUCCCGA CUGAUGAGGCCGUUAGGCCGAA AGCUUUUC
13341





5994
AAAGCUAUC GGGAUUCU
3936
AGAAUCCC CUGAUGAGGCCGUUAGGCCGAA AUAGCUUU
13342





6000
AUCGGGAUU CUCUGGUU
3937
AACCAGAG CUGAUGAGGCCGUUAGGCCGAA AUCCCGAU
13343





6001
UCGGGAUUC UCUGGUUC
3938
GAACCAGA CUGAUGAGGCCGUUAGGCCGAA AAUCCCGA
13344





6003
GGGAUUCUC UGGUUCUG
3939
CAGAACCA CUGAUGAGGCCGUUAGGCCGAA AGAAUCCC
13345





6008
UCUCUGGUU CUGCUUAA
3940
UUAAGCAG CUGAUGAGGCCGUUAGGCCGAA ACCAGAGA
13346





6009
CUCUGGUUC UGCUUAAA
3941
UUUAAGCA CUGAUGAGGCCGUUAGGCCGAA AACCAGAG
13347





6014
GUUCUGCUU AAAGACUU
3942
AAGUCUUU CUGAUGAGGCCGUUAGGCCGAA AGCAGAAC
13348





6015
UUCUGCUUA AAGACUUA
3943
UAAGUCUU CUGAUGAGGCCGUUAGGCCGAA AAGCAGAA
13349





6022
UAAAGACUU AGCUUUGG
3944
CCAAAGCU CUGAUGAGGCCGUUAGGCCGAA AGUCUUUA
13350





6023
AAAGACUUA GCUUUGGA
3945
UCCAAAGC CUGAUGAGGCCGUUAGGCCGAA AAGUCUUU
13351





6027
ACUUAGCUU UGGAGCCU
3946
AGGCUCCA CUGAUGAGGCCGUUAGGCCGAA AGCUAAGU
13352





6028
CUUAGCUUU GGAGCCUA
3947
UAGGCUCC CUGAUGAGGCCGUUAGGCCGAA AAGCUAAG
13353





6036
UGGAGCCUA UGAAAGUU
3948
AACUUUCA CUGAUGAGGCCGUUAGGCCGAA AGGCUCCA
13354





6044
AUGAAAGUU GAUCAGCC
3949
GGCUGAUC CUGAUGAGGCCGUUAGGCCGAA ACUUUCAU
13355






Where “X” represents stem II region of a HH ribozyme (Hertel et al., 1992 Nucleic Acids Res. 20 3252).




The length of stem II may be 2 base-pairs.




Underlined region can be any X sequence or linker, as described herein.








[0348]

12






TABLE IX










Mouse flt1 VEGF Receptor-Hairpin Ribozyme and Substrate Sequence















Seq

Seq





ID

ID


Pos
Substrate
No
HP Ribozyme
No















33
AUGGUCA GCU GCUGGGAC
3950
GUCCCAGC AGAA GACCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13356






36
GUCAGCU GCU GGGACACC
3951
GGUGUCCC AGAA GCUGAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13357





50
CACCGCG GUC UUGCCUUA
3952
UAAGGCAA AGAA GCGGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13358





67
ACGCGCU GCU CGGGUGUC
3953
GACACCCG AGAA GCGCGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13359





79
GGUGUCU GCU UCUCACAG
3954
CUGUGAGA AGAA GACACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13360





166
CAGGCCA GAC UCUCUUUC
3955
GAAAGAGA AGAA GGCCUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13361





197
GGAGGCA GCC CACUCAUG
3956
CAUGAGUG AGAA GCCUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13362





214
GGUCUCU GCC CACGACCG
3957
GGGUCGUG AGAA GAGACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13363





266
CCCAUCG GCC UGUGGGAG
3958
CUCCCACA AGAA GAUGGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13364





487
GAAGACA GCU CAUCAUCC
3959
GGAUGAUG AGAA GUCUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13365





501
AUCCCCU GCC GGGUGACG
3960
CGUCACCC AGAA GGGGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13366





566
UACCCCU GAU GGGCAAAG
3961
CUUUGCCC AGAA GGGGUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13367





640
UAGGACU GCU GAACUGCG
3962
CGCAGUUC AGAA GUCCUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13368





691
ACUAUCU GAC CCAUCGGC
3963
GCCGAUGG AGAA GAUAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13369





703
AUCGGCA GAC CAAUACAA
3964
UUGUAUUG AGAA GCCGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13370





736
UACGCCC GCC GAGCCCAG
3965
CUGGGCUC AGAA GGCGUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13371





754
UGAGACU GCU CCACGGGC
3966
GCCCGUGG AGAA GUCUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13372





766
ACGGGCA GAC UCUUGUCC
3967
GGACAAGA AGAA GCCCGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13373





871
GGCAGCG GAU UGACCGGA
3968
UCCGGUCA AGAA GCUGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13374





960
UACACCU GUC GCGUGAAG
3969
CUUCACGC AGAA GGUGUA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13375





988
CGUUCCA GUC UUUCAACA
3970
UGUUGAAA AGAA GGAACG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13376





1051
GGAAGCA GCC GGUGCAGG
3971
CCUGCACC AGAA GCUUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13377





1081
GAAGACG GUC CUAUCGGC
3972
GCCGAUAG AGAA GUCUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13378





1090
CCUAUCG GCU GUCCAUGA
3973
UCAUGGAC AGAA GAUAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13379





1093
AUCGGCU GUC CAUGAAAG
3974
CUUUCAUG AGAA GCCGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13380





1169
GAAGUCU GCU CGCUAUUU
3975
AAAUAGCG AGAA GACUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13381





1315
AACCUCA GAU CUACGAAA
3976
UUUCGUAG AGAA GAGGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13382





1363
UCUAUCC GCU GGGCAGCA
3977
UGCUGCCC AGAA GAUAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13383





1604
GGUGGCU GAC UCUCAGAC
3978
GUCUGAGA AGAA GCCACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13384





1612
ACUCUCA GAC CCCUGGAA
3979
UUCCAGGG AGAA GAGAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13385





1629
AUCUACA GCU GCCGGGCC
3980
GGCCCGGC AGAA GUAGAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13386





1632
UACAGCU GCC GGGCCUUC
3981
GAAGCCCC AGAA GCUGUA ACCAGACAAACACACGUUGUGGUACAUUACCUGGUA
13387





1688
UGUCACA GAU GUGCCGAA
3982
UUCGGCAC AGAA GUGACA ACCAGAGAAACACACGUUCUGGUACAUUACCUCGUA
13388





1730
GAUGCCA GCC CAAGGAGA
3983
UCUCCUUC AGAA GGCAUC ACCACAGAAACACACGUUCUGGUACAUUACCUGGUA
13389





1753
UCAAACU CUC CUCUCUGG
3984
CCACACAG AGAA GUUUCA ACCAGAGUAACACACGUUGUGGUACAUUACCUGGUA
13390





2017
CACACCU GCU UCAAAACC
3985
GGUUUUGA AGAA GGUGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13391





2101
CGCCUCA GAU CACUUGGU
3986
ACCAAGUG AGAA GAGGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13392





2176
GCACGCU GUU UAUUCAAA
1441
UUUCAAUA AGAA GCGUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10860





2258
AACCGCA GCC UACCUCAC
3987
GUCAGGUA AGAA GCGCUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13393





2305
UGGAGCU GAU CACGCUCA
3988
UGAGCGUG AGAA GCUCCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13394





2383
UGAAGCG GUC UUCUUCCG
3989
CGGAAGAA AGAA GCUUCA ACCAGAGAAACACACGUUGUCCUACAUUACCUGGUA
13395





2405
AAACACA GAC UACCUGUC
3990
GACACGUA AGAA GUCUUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13396





2432
GGACCCA GAU GAAGUUCC
1445
GGAACUUC AGAA GGGUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
10864





2464
GUGAACG GCU GCCCUAUG
3991
CAUAGGCC AGAA GUUCAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13397





2467
AACGGCU GCC CUAUGAUC
3992
CAUCAUAG AGAA GCCGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13398





2592
CCCACCU GCC GGACUGUG
3993
CACAGUCC AGAA GGUGCG ACCAGAGAAACACACCUUGUGGUACAUUACCUGGUA
13399





2596
CCUGCCG GAC UGUGGCUG
3994
CAGCCACA AGAA GGCACG ACCAGAGAAACACACCUUGUGGUACAUUACCUGGUA
13400





2653
AAGCUCU GAU GACCGAAC
3995
GUUCGGUC AGAA GAGCUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13401





2743
GGCCUCU GAU GGUGAUCG
3996
CGAUCACC AGAA GAGGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13402





2779
GAAACCU GUC CAACUACC
3997
GGUAGUUG AGAA GGUUUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13403





2814
UUAUUCU GUC UCAACAAG
3998
CUUGUUGA AGAA GAAUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13404





2831
GGACGCA GCC UUGCAUAU
3999
AUAUGCAA AGAA GCGUCC ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
13405





2895
AACCCCC CCC UAGACAGU
4000
ACUGUCUA AGAA GGGCUU ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
13406





2913
GUCAGCA GCU CAACUGUC
4001
GACACUUG AGAA GCUGAC ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
13407





2928
GUCACCA GCU CCACCUUC
4002
GAACCUGG AGAA GGUGAC ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
13408





2934
AGCUCCA GCU UCCCUGAA
4003
UUCAGGGA AGAA GGAGCU ACCAGAGAAACACACGUUCUGGUACAUUACCUGGUA
13409





3001
CCAAGCA GCC CCUCACCA
4004
UGGUCACC AGAA GCUUCG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13410





3022
AACACCU GAU UUCCUACA
4005
UGUAGGAA AGAA GGUCUU ACCAGACAAACACACGUUGUGGUACAUUACCUGGUA
13411





3033
UCCUACA GUU UCCAAGUG
4006
CACUUCGA AGAA GUAGGA ACCAGACAAACACACGUUGUGGUACAUUACCUGGUA
13412





3064
ACUUUCU GUC CUCCACAA
4007
UUCUGGAG AGAA GAAACU ACCAGACAAACACACGUUGUGGUACAUUACCUGGUA
13413





3179
GAACCCU GAU UAUGUGAG
4008
CUCACAUA AGAA GGCUUC ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
10876





3357
UUCUGCA GCC GCCUGAAG
4009
CUUCAGGC AGAA GCAGAA ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13414





3360
UGCAGCC GCC UGAAGGAA
4010
UUCCUUCA AGAA GCUGCA ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13415





3379
GCAUGCG GAU GAGAACCC
4011
GGGUUCUC AGAA GCAUGC ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13416





3463
GGCCCCG GUU UGCUGAAC
4012
GUUCAGCA AGAA GGGGCC ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13417





3496
GUGACCU GCU UCAAGCCA
4013
UGGCUUGA AGAA GGUCAC ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13418





3553
CCAUACU GAC UAGAAACA
4014
UGUUUCUA AGAA GUAUGG ACCAGACAAACACACGUUCUGGUACAUUACCUGGUA
13419





3615
AAGGACG GCU UUGCAGAU
4015
AUCUGCAA AGAA GUCCUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13420





3623
CUUUGCA GAU CCACAUUU
4016
AAAUGUGG AGAA GCAAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13421





3650
AAGCUCU GAU GAUGUGAG
4017
CUCACAUC AGAA GAGCUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13422





3754
ACUAUCA GCU GGACACUA
4018
UAGUGUCC AGAA GAUAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13423





3772
GCACUCU GCU GGGCUCCC
4019
GGGAGCCC AGAA GAGUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13424





3796
UGAAGCG GUU CACCUGGA
4020
UCCAGGUG AGAA GCUUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13425





3881
ACUUUCC GAU CUGCCGAG
4021
CUCGGCAG AGAA GAAAGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13426





3886
CCGAUCU GCC GAGGCCCA
4022
UGGGCCUC AGAA GAUCGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13427





3897
AGGCCCA GCU UCUGCUUC
4023
GAAGCAGA AGAA GGGCCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13428





3903
AGCUUCU GCU UCUCCAGC
4024
GCUGGAGA AGAA GAAGCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13429





3912
UUCUCCA GCU GUGGCCAC
4025
GUGGCCAC AGAA GGAGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13430





3969
GAGUCCU GCU GUUCUCCA
4026
UGGAGAAC AGAA GGACUC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13431





3972
UCCUGCU GUU CUCCACCC
4027
GGGUGGAG AGAA GCAGGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13432





3986
ACCCCCA GAC UACAACUC
4028
GAGUUGUA AGAA GGGGGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13433





4018
CCUCCCC GCC CGCCUAAA
4029
UUUAGGCG AGAA GGGAGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13434





4022
CCCGCCC GCC UAAAGCUU
4030
AAGCUUUA AGAA GGCGGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13435





4040
CUCACCA GCC CCGACAAC
4031
GUUGUCGG AGAA GGUGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13436





4053
ACAACCA GCC CCUGACAG
4032
CUGUCAGG AGAA GGUUGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13437





4095
CUAUUCC GCU CCACAGGA
4033
UCCUGUGG AGAA GAAUAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13438





4110
GGAGCCA GCU GCUUUUCG
4034
CGAAAAGC AGAA GGCUCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13439





4113
GCCAGCU GCU UUUCGUGA
4035
UCACGAAA AGAA GCUGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13440





4168
UGUUGCU GUU UUGACUAA
4036
UUAGUCAA AGAA GCAACA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13441





4290
GGCGACC GCC CGCCCACC
4037
GGUGGGCG AGAA GUCGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13442





4294
ACCGCCC GCC CACCGGCC
4038
GGCCGGUG AGAA GGCGGU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13443





4329
CCCUGCA GCU GUGGGACU
4039
AGUCCCAC AGAA GCAGGG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13444





4378
AUGCACU GAC CUGGUCUG
4040
CAGACCAG AGAA GUCCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13445





4383
CUGACCU GCU CUGUCUCU
4041
AGAGACAG AGAA GGUCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13446





4388
CUGCUCU GUC UCUCUUAU
4042
AUAAGAGA AGAA GAGCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13447





4457
UGCGUCC GUC CUGUGGAG
4043
CUCCACAG AGAA GACGCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13448





4525
GGCCUCC GCU GUUUCGGG
4044
CCCGAAAC AGAA GAGGCC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13449





4528
CUCCGCU GUU UCGGGCCC
4045
GGGCCCGA AGAA GCGGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13450





4643
GUCUUCU GUU GUCUGUUU
4046
AAACAGAC AGAA GAAGAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13451





4650
GUUGUCU GUU UACCAUCC
4047
GGAUGGUA AGAA GACAAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13452





4724
AUCAUCA GUU CCUCUAGU
4048
ACUAGAGG AGAA GAUGAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13453





4771
CAGGCCU GAC CUUCGCAU
4049
AUGCGAAG AGAA GGCCUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13454





4785
GCAUACU GCU CACGGGGA
4050
UCCCCGUG AGAA GUAUGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13455





4809
UGGUCCA GUU UGGCCUAG
4051
CUAGGCCA AGAA GGACCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13456





4834
GCCUACU GAU GGGCUCAA
4052
UUGAGCCC AGAA GUAGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13457





4912
UUAUCCU GUU UUAUAUAU
4053
AUAUAUAA AGAA GGAUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13458





5119
CAAGGCA GUC UGAGAGGA
4054
UCCUCUCA AGAA GCCUUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13459





5144
AGUAUCA GCC CAUAUUUA
4055
UAAAUAUG AGAA GAUACU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13460





5287
UUCAUCU GUU UCAUACCU
4056
AGGUAUGA AGAA GAUGAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13461





5363
GGUGCCC GCU CUUUGGGG
4057
CCCCAAAG AGAA GGCACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13462





5462
CACACCU GCC GGAGCCGG
4058
CCGGCUCC AGAA GGUGUG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13463





5478
GGUCACA GCU GGGCAGAC
4059
GUCUGCCC AGAA GUGACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13464





5486
CUGGGCA GAC GAUGAAUA
4060
UAUUCAUC AGAA GCCCAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13465





5500
AAUAGCU GCU UUGGGAGA
4061
UCUCCCAA AGAA GCUAUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13466





5539
AUUCUCU GAC CGGGCCAG
4062
CUGGCCCG AGAA GAGAAU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13467





5564
GGUACCU GCU CCCCUGUG
4063
CACAGGGG AGAA GGUACC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13468





5597
GUUUUCU GUC UGAUGAGA
4064
UCUCAUCA AGAA GAAAAC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13469





5601
UCUGUCU GAU GAGACUGG
4065
CCAGUCUC AGAA GACAGA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13470





5639
UGAGACA GCC UGCAGCCC
4066
GGGCUGCA AGAA GUCUCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13471





5646
GCCUGCA GCC CACUGUGG
4067
CCACAGUG AGAA GCAGGC ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13472





5781
CUUGUCG GCU GCAGUGUG
4068
CACACUGC AGAA GACAAG ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13473





5829
AGAAACG GAU GAGAACAG
4069
CUGUUCUC AGAA GUUUCU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13474





5842
AACAGCA GCC UGAGGUUU
4070
AAACCUCA AGAA GCUGUU ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13475





5915
UUAUUCC GAU UUUAAUAA
4071
UUAUUAAA AGAA GAAUAA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13476





6010
UGGUUCU GCU UAAAGACU
4072
AGUCUUUA AGAA GAACCA ACCAGAGAAACACACGUUGUGGUACAUUACCUGGUA
13477










[0349]

13






TABLE X










Homologous Hammerhead Ribozyme Target Sites Between



Human flt-1 and KDR RNA













nt.
flt-1
Seq
nt.
KDR




Position
Target Sequence
ID No
Position
Target Sequence
Seq ID No
















3388
CCGGGAU A UUUAUAA
4073
3151
CCGGGAU A UUUAUAA
4073






2174
AAUGUAU A CACAGGG
4074
3069
AgUGUAU C CACAGGG
4116





2990
UCCAAAU A UGGAAAU
4075
2756
UGCAAAU u UGGAAAc
4117





2693
CUCCCUU A UGAUGCC
4076
2459
CUgCCUU A UGAUGCC
4118





2981
GUUGAAU A CUGCAAA
4077
2747
GUgGAAU u CUGCAAA
4119





1359
UAUGGUU A AAAGAUG
4078
2097
U9UGGUU u AAAGAUa
4120





3390
GGGAUAU U UAUAAGA
4079
3153
GGGAUAU U UAUAAag
4121





3391
GGAUAUU U AUAAGAA
4080
3154
GGAUAUU U AUAAagA
4122





2925
ACGUGGU U AACCUGC
4081
2691
AuGUGGU a AACCUuC
4123





7140
UAUUUCU A GUCAUGA
4082
2340
UAcUUCU u GUCAUCA
4124





1785
CAAUAAU A GAAGGAA
4083
1515
CucUAAU U GAAGGAA
4125





2731
GAGACUU A AACUGGG
4084
768
uuGACUU a AACUGGG
4126





3974
GAUGACU A CCAGGGC
4085
1466
GAgGACU u CCAGGGa
4127





6590
UUAAUGU A GAAAGAA
4086
2603
aaAAUGU u GAAAGAA
4128





6705
GCCAUUU A UGACAAA
4087
3227
aCaAUUU u UGACAgA
4129





974
GUCAAAU U ACUUAGA
4088
147
uUCAAAU U ACUUgcA
4130





1872
AUAAAGU U GGGACUG
4089
1602
ACAAAGU a GGGAgaG
4131





2333
ACUUGGU U UAAAAAC
4090
1088
AaaUGGU a UAAAAAu
4132





2775
AAGUGGU U CAAGCAU
4091
1745
AcaUGGU a CAAGCuU
4133





3533
UUCUCCU U AGGUGGG
4092
3296
UUuUCCU U AGGUGcu
4134





3534
UCUCCUU A GGUGGGU
4093
3297
UuUCCUU A GGUGcuU
4135





3625
GUACUCU A CUCCUGA
4094
4054
GagCUCU a CUCCUGu
4136





1814
AGCACCU U GGUUGUG
4095
1059
AGuACCU U GGUUacc
4137





2744
GGCAAAU C ACUUGGA
4096
147
uuCAAAU u ACUUGcA
4130





2783
CAAGCAU C AGCAUUU
4097
796
gAAGCAU C AGCAUaa
4138





3613
GAGAGCU C CUGAGGA
4098
2968
GgaAGCU C CUGAagA
4139





4052
AAGGCCU C GCUCAAG
4099
1923
ucuGCCU u GCUCAAG
4140





5305
UCUCCAU A UCAAAAC
4100
456
ggUCCAU U UCAAAuC
4141





7155
AUGUAUU U UGUAUAC
4101
631
gUcUAUU a UGUAcAu
4142





1836
CUAGAAU U UCUGGAA
4102
1007
aUgGAAU a UCUGGug
4143





2565
CUCUCUU C UGGCUCC
4103
2328
uguUCUU C UGGCUaC
4144





4250
CUGUACU C CACCCCA
4104
3388
uUaUACU a CACCagA
4145





7124
ACAUGGU U UGGUCCU
4105
3778
cagUGGU a UGGUuCU
4146





436
AUGGUCU U UGCCUGA
4106
1337
AcGGUCU a UGCCauu
4147





2234
GCACCAU A CCUCCUG
4107
1344
augCCAU U CCUCCcc
4148





2763
GGGCUUU U GGAAAAG
4108
990
uuGCUUU U GGAAgUG
4149





4229
CCAGACU A CAACUCG
4109
767
auuGACU u CAACUgG
4150





5301
GUUUUCU C CAUAUCA
4110
3307
ugcUUCU C CAUAUCc
4151





6015
AGAAUGU A UGCCUCU
4111
1917
AcuAUGU C UGCCUug
4152





6095
AUUCCCU A GUGAGCC
4112
1438
AUaCCCU u GUGAaya
4153





6236
UGUUGUU C CUCUUCU
4113
76
UagUGUU u CUCUUga
4154





5962
GCUUCCU U UUAUCCA
4114
3099
auaUCCU a UUAUCgg
4155





7629
UAUAUAU U CUCUGCU
4115
3096
gAaAUAU a CUCUuaU
4156






Lowercase letters are used to represent sequence variance between flt-1 and KDR RNA








[0350]

14










TABLE XI














Wait Time* 2′-
Wait Time*


Reagent
Equivalents
Amount
Wait Time* DNA
O-methyl
RNA










A. 2.5 μmol Synthesis Cycle ABI 394 Instrument












Phosphoramidites
6.5
 163 μL
 45 sec
 2.5 min
 7.5 min


S-Ethyl Tetrazole
23.8
 238 μL
 45 sec
 2.5 min
 7.5 min


Acetic Anhydride
100
 233 μL
 5 sec
 5 sec
 5 sec


N-Methyl Imidazole
186
 233 μL
 5 sec
 5 sec
 5 sec


TCA
176
 2.3 mL
 21 sec
 21 sec
 21 sec


Iodine
11.2
 1.7 mL
 45 sec
 45 sec
 45 sec


Beaucage
12.9
 645 μL
100 sec
300 sec
300 sec


Acetonitrile
NA
6.67 mL
NA
NA
NA







B. 0.2 μmol Synthesis Cycle ABI 394 Instrument












Phosphoramidites
15
  31 μL
 45 sec
233 sec
465 sec


S-Ethyl Tetrazole
38.7
  31 μL
 45 sec
233 min
465 sec


Acetic Anhydride
655
 124 μL
 5 sec
 5 sec
 5 sec


N-Methyl Imidazole
1245
 124 μL
 5 sec
 5 sec
 5 sec


TCA
700
 732 μL
 10 sec
 10 sec
 10 sec


Iodine
20.6
 244 μL
 15 sec
 15 sec
 15 sec


Beaucage
7.7
 232 μL
100 sec
300 sec
300 sec


Acetonitrile
NA
2.64 mL
NA
NA
NA
















Equivalents
Amount
Wait Time*
Wait Time* 2′-O-



Reagent
DNA/2′-O-methyl/Ribo
DNA/2′-O-methyl/Ribo
DNA
methyl
Wait Time* Ribo










C. 0.2 μmol Synthesis Cycle 96 well Instrument












Phosphoramidites
22/33/66
40/60/120 μL
 60 sec
180 sec
360 sec


S-Ethyl Tetrazole
70/105/210
40/60/120 μL
 60 sec
180 min
360 sec


Acetic Anhydride
265/265/265
50/50/50 μL
 10 sec
 10 sec
 10 sec


N-Methyl Imidazole
502/502/502
50/50/50 μL
 10 sec
 10 sec
 10 sec


TCA
238/475/475
250/500/500 μL
 15 sec
 15 sec
 15 sec


Iodine
6.8/6.8/6.8
80/80/80 μL
 30 sec
 30 sec
 30 sec


Beaucage
34/51/51
80/120/120
100 sec
200 sec
200 sec


Acetonitrile
NA
1150/1150/1150 μL
NA
NA
NA






*Wait time does not include contact time during delivery.








[0351]

15






TABLE XII










Ribozyme and attenuated control sequences and locations of modified nucleotides.














RPI


Seq.



Target Site*
No.
Ribozyme Sequence(5′-3′)
Activity
ID No.















Flt-1358-amino
RPI 4118
5′ asuscsusuuu cUGAUGaggcgaaagccGaa AccauacB 3′
Active
13478






Flt-1358-amino (att.)
RPI 4581
asuscsusuuu cUuAUGaggcgaaagccGau AccauacB
Attenuated
13479





Flt-1358-allyl
RPI 4159
5′ asuscsUsuuu cUGAuGaggcgaaagccGaa AccauacB 3′
Active
13480





Flt-1358-allyl (att.)
RPI 4583
asuscsusuuu cUuAuGaggcgaaagccGau AccauacB
Attenuated
13481





Flt-4229-amino
RPI 4131
gsasgsusug cUGAUGaggcgaaagccGaa AgucugB
Active
13482





Flt-4229-amino (att.)
RPI 4582
gsasgsusug cUuAUGaggcgaaagccGau AgucugB
Attenuated
13483





Flt-4229-allyl
RPI 4172
gsasgsusug cUGAuGaggcgaaagccGaa AgucugB
Active
13484





Flt-4229-allyl (att.)
RPI 4584
gsasgsusug cUUAuGaggcgaaagccGau AgucugB
Attenuated
13485





KDR-726-amino
RPI 4097
usascsasauu cUGAUCaggcgaagccGaa AagacaaB
Active
13486





KDR-726-amino (att.)
RPI 4674
usascsasauu cUuAUGaggcgaaagccGau Aagacaab
Attenuated
13487





KDR-726-allyl
RPI 4138
usascsasauu cUGAuGaggcgaaagccGaa AagacaaB
Active
13488





KDR-726allyl (att.)

usascsasauu cUuAuGaggcgaagccGau AagacaaB
Attenuated
13489





KDR-3950-amino
RPI 4110
csusgsgsag cUGAUGaggcgaaagccGaa AcacggB
Active
13490





KDR-3950-amino (att.)
RPI 4677
csusgsgsag cUuAUGaggcgaaagccGau AcacggB
Attenuated
13491





KDR-3950-allyl
RPI 4151
csusgsgsag cUcAuGaggcgaaagccGaa AcacggB
Active
13492





KDR-3950-allyl (att.)

csusgsgsag cUuAuGaggcgaaagccGau AcacggB
Attenuated
13493







binding arm/catalytic core & stem II/binding arm






*Ribozyme target sites are named according to the cleavage position in human Flt-1 (EMBL accession no. X51602) or human KDR mRNA (EMBL accession no. L0497).




\ Modifications are indicated as follows: 2′-O-methyl nucleotides, lowercase; ribonucleotides, uppercase G, A; inverted 3′-3′deoxyabasic, B. Two ribozyme motifs were tested23. For the NH2-modified ribozymes, U indicates the two core positions where 2′-NH2 uridines are present. U indicates 2′-C-allyl-uridine modification. The positions of four phosphorothioate linkages at the 5′ end are indicated by a subscript ”s⇄.




Changes in the attenuated controls are underlined. Nucleotides comprising the base paired region of stem II are in italics. A 3 bp stem II is shown above.




Ribozymes or attenuated controls referred to in the text with a 4 bp stem II have one additional base pair such that the stem II/loop sequence is ggccgaaaggcc.








[0352]

16






TABLE XIII










Ribozyme and attenuated control sequences with locations of modified



nucleotides.














Seq






ID


Ribozyme
Sequence (5′-3′)
Activity
Nos.














RPI.4610
gsasgsusug cUGAuGaggccgaaaggccGaa AgucugB
Active
13494



(ANGIOZYME™)





RPI.13141
gsasgsusug cUAGaGaggccgaaggccGauAgucugB
BAC†
13499





RPI.13030
gsasasgsgu cUAGuGaggccgaaaggccGauAugucB
BAC‡
13496



binding arm/core & stem II/binding arm






†Modifications are indicated as follows: 2′-O-methyl nucleotides, lowercase; ribonucleotides, uppercase G, A; 2′- C-allyl uridine, U; inverted 3′-3′ deoxyabasic, B. The positions of four phosphorothioate linkages at the 5′ end are indicated by a subscript “s”. Nucleotides comprising the base paired region of stem II are in italics. Nucleotide changes in the core of the attenuated controls are underlined. ANGIOZYME ribozyme is targeted to



# cleave site 4229 in human flt-1 RNA and is identical to Flt-4229-allyl ribozyme (Table XII) except that the ANGIOZYME has a stem II of length 4 bps.



‡BAc: Binding arm, Attenuated core Control.




*SAC: Scrambled arm, Attenuated core Control.








[0353]

17






TABLE XIV










NCH Ribozyme and Target Sequences















Seq ID

Seq ID



Pos
Target
No
NCH Ribozyme
No















9
GCGGACAC U CCUCUCGG
4157
CCGAGAGG CUGAUGAGGCCGUUAGGCCGAA IUGUCCGC
13497






11
GGACACUC C UCUCGGCU
4158
AGCCGAGA CUGAUGAGGCCGUUAGGCCGAA IAGUGUCC
13498





12
GACACUCC U CUCGGCUC
4159
GAGCCGAG CUGAUGAGGCCGUUAGGCCGAA IGAGUGUC
13499





14
CACUCCUC U CGGCUCCU
4160
AGGAGCCG CUGAUGAGGCCGUUAGGCCGAA IAGGAGUG
13500





19
CUCUCGGC U CCUCCCCG
4161
CGGGGAGG CUGAUGAGGCCGUUAGGCCGAA ICCGAGAG
13501





21
CUCGGCUC C UCCCCGGC
4162
GCCGGGGA CUGAUGAGGCCGUUAGGCCGAA IAGCCGAG
13502





22
UCGGCUCC U CCCCGGCA
4163
UGCCGGGG CUGAUGAGGCCGUUAGGCCGAA IGAGCCGA
13503





24
GGCUCCUC C CCGGCAGC
4164
GCUGCCGG CUGAUGAGGCCGUUAGGCCGAA IAGGAGCC
13504





25
GCUCCUCC C CGGCAGCG
4165
CGCUGCCG CUGAUGAGGCCGUUAGGCCGAA IGAGGAGC
13505





26
CUCCUCCC C GGCAGCGG
4166
CCGCUGCC CUGAUGAGGCCGUUAGGCCGAA IGGAGGAG
13506





30
UCCCCGGC A GCGGCGGC
4167
GCCGCCGC CUGAUGAGGCCGUUAGGCCGAA ICCGGGGA
13507





42
GCGGCGGC U CGGAGCGG
4168
CCGCUCCG CUGAUGAGGCCGUUAGGCCGAA ICCGCCGC
13508





53
GAGCGGGC U CCGGGGCU
4169
AGCCCCGG CUGAUGAGGCCGUUAGGCCGAA ICCCGCUC
13509





55
GCGGGCUC C GGGGCUCG
4170
CGAGCCCC CUGAUGAGGCCGUUAGGCCGAA IAGCCCGC
13510





61
UCCGGGGC U CGGGUGCA
4171
UGCACCCG CUGAUGAGGCCGUUAGGCCGAA ICCCCGGA
13511





69
UCGGGUGC A GCGGCCAG
4172
CUGGCCGC CUGAUGAGGCCGUUAGGCCGAA ICACCCGA
13512





75
GCAGCGGC C AGCGGGCC
4173
GGCCCGCU CUGAUGAGGCCGUUAGGCCGAA ICCGCUGC
13513





76
CAGCGGCC A GCGGGCCU
4174
AGGCCCGC CUGAUGAGGCCGUUAGGCCGAA IGCCGCUG
13514





83
CAGCGGGC C UGGCGGCG
4175
CGCCGCCA CUGAUGAGGCCGUUAGGCCGAA ICCCGCUG
13515





84
AGCGGGCC U GGCGGCGA
4176
UCGCCGCC CUGAUGAGGCCGUUAGGCCGAA IGCCCGCU
13516





100
AGGAUUAC C CGGGGAAG
4177
CUUCCCCG CUGAUGAGGCCGUUAGGCCGAA IUAAUCCU
13517





101
GGAUUACC C GGGGAAGU
4178
ACUUCCCC CUGAUGAGGCCGUUAGGCCGAA IGUAAUCC
13518





117
UGGUUGUC U CCUGGCUG
4179
CAGCCAGG CUGAUGAGGCCGUUAGGCCGAA IACAACCA
13519





119
GUUGUCUC C UGGCUGGA
4180
UCCAGCCA CUGAUGAGGCCGUUAGGCCGAA IAGACAAC
13520





120
UUGUCUCC U GGCUGGAG
4181
CUCCAGCC CUGAUGAGGCCGUUAGGCCGAA IGAGACAA
13521





124
CUCCUGGC U GGAGCCGC
4182
GCGGCUCC CUGAUGAGGCCGUUAGGCCGAA ICCAGGAG
13522





130
GCUGGAGC C GCGAGACG
4183
CGUCUCGC CUGAUGAGGCCGUUAGGCCGAA ICUCCAGC
13523





144
ACGGGCGC U CAGGGCGC
4184
GCGCCCUG CUGAUGAGGCCGUUAGGCCGAA ICGCCCGU
13524





146
GGGCGCUC A GGGCGCGG
4185
CCGCGCCC CUGAUGAGGCCGUUAGGCCGAA IAGCGCCC
13525





158
CGCGGGGC C GGCGGCGG
4186
CCGCCGCC CUGAUGAGGCCGUUAGGCCGAA ICCCCGCG
13526





184
GGACGGAC U CUGGCGGC
4187
GCCGCCAG CUGAUGAGGCCGUUAGGCCGAA IUCCGUCC
13527





186
ACGGACUC U GGCGGCCG
4188
CGGCCGCC CUGAUGAGGCCGUUAGGCCGAA IAGUCCGU
13528





193
CUGGCGGC C GGGUCGUU
4189
AACGACCC CUGAUGAGGCCGUUAGGCCGAA ICCGCCAG
13529





205
UCGUUGGC C GGGGGAGC
4190
GCUCCCCC CUGAUGAGGCCGUUAGGCCGAA ICCAACGA
13530





220
GCGCGGGC A CCGGGCGA
4191
UCGCCCGG CUGAUGAGGCCGUUAGGCCGAA ICCCGCGC
13531





222
GCGGGCAC C GGGCGAGC
4192
GCUCGCCC CUGAUGAGGCCGUUAGGCCGAA IUGCCCGC
13532





231
GGGCGAGC A GGCCGCGU
4193
ACGCGGCC CUGAUGAGGCCGUUAGGCCGAA ICUCGCCC
13533





235
GAGCAGGC C GCGUCGCG
4194
CGCGACGC CUGAUGAGGCCGUUAGGCCGAA ICCUGCUC
13534





245
CGUCGCGC U CACCAUGG
4195
CCAUGGUG CUGAUGAGGCCGUUAGGCCGAA ICGCGACG
13535





247
UCGCGCUC A CCAUGGUC
4196
GACCAUGG CUGAUGAGGCCGUUAGGCCGAA IAGCGCGA
13536





249
GCGCUCAC C AUGGUCAG
4197
CUGACCAU CUGAUGAGGCCGUUAGGCCGAA IUGAGCGC
13537





250
CGCUCACC A UGGUCAGC
4198
GCUGACCA CUGAUGAGGCCGUUAGGCCGAA IGUGAGCG
13538





256
CCAUGGUC A GCUACUGG
4199
CCAGUAGC CUGAUGAGGCCGUUAGGCCGAA IACCAUGG
13539





259
UGGUCAGC U ACUGGGAC
4200
GUCCCAGU CUGAUGAGGCCGUUAGGCCGAA ICUGACCA
13540





262
UCAGCUAC U GGGACACC
4201
GGUGUCCC CUGAUGAGGCCGUUAGGCCGAA IUAGCUGA
13541





268
ACUGGGAC A CCGGGGUC
4202
GACCCCGG CUGAUGAGGCCGUUAGGCCGAA IUCCCAGU
13542





270
UGGGACAC C GCGGUCCU
4203
AGGACCCC CUGAUGAGGCCGUUAGGCCGAA IUGUCCCA
13543





277
CCGGGGUC C UGCUGUGC
4204
GCACAGCA CUGAUGAGGCCGUUAGGCCGAA IACCCCGG
13544





278
CGGGGUCC U GCUGUGCG
4205
CGCACAGC CUGAUGAGGCCGUUAGGCCGAA IGACCCCG
13545





281
GGUCCUGC U GUGCGCGC
4206
GCGCGCAC CUGAUGAGGCCGUUAGGCCGAA ICAGGACC
13546





290
GUGCGCGC U GCUCAGCU
4207
AGCUGAGC CUGAUGAGGCCGUUAGCCCGAA ICGCGCAC
13547





293
CGCGCUGC U CAGCUGUC
4208
GACAGCUG CUGAUGAGGCCGUUAGGCCGAA ICAGCGCG
13548





295
CGCUGCUC A GCUGUCUG
4209
CAGACAGC CUGAUGAGGCCGUUAGGCCGAA IAGCAGCG
13549





298
UGCUCAGC U GUCUGCUU
4210
AAGCAGAC CUGAUGAGGCCGUUAGGCCGAA ICUGAGCA
13550





302
CAGCUGUC U GCUUCUCA
4211
UGAGAAGC CUGAUGAGGCCGUUAGCCCGAA IACAGCUG
13551





305
CUGUCUGC U UCUCACAG
4212
CUGUGAGA CUGAUGAGGCCGUUAGGCCGAA ICAGACAG
13552





308
UCUGCUUC U CACAGGAU
4213
AUCCUGUG CUGAUGAGGCCGUUAGGCCGAA IAAGCAGA
13553





310
UGCUUCUC A CAGGAUCU
4214
AGAUCCUG CUGAUGAGGCCGUUAGGCCGAA IAGAAGCA
13554





312
CUUCUCAC A GGAUCUAG
4215
CUAGAUCC CUGAUGAGGCCGUUAGGCCGAA IUGAGAAG
13555





318
ACAGGAUC U AGUUCAGG
4216
CCUGAACU CUGAUGAGGCCGUUAGGCCGAA IAUCCUGU
13556





324
UCUAGUUC A GGUUCAAA
4217
UUUGAACC CUGAUGAGGCCGUUAGGCCGAA IAACUAGA
13557





330
UCAGGUUC A AAAUUAAA
4218
UUUAAUUU CUGAUGAGGCCGUUAGGCCGAA IAACCUGA
13558





344
AAAAGAUC C UGAACUGA
4219
UCAGUUCA CUGAUGAGGCCGUUAGGCCGAA IAUCUUUU
13559





345
AAAGAUCC U GAACUGAG
4220
CUCAGUUC CUGAUGAGGCCGUUAGGCCGAA IGAUCUUU
13560





350
UCCUGAAC U GAGUUUAA
4221
UUAAACUC CUGAUGAGGCCGUUAGGCCGAA IUUCAGGA
13561





364
UAAAAGGC A CCCAGCAC
4222
GUGCUGGG CUGAUGAGGCCGUUAGGCCGAA ICCUUUUA
13562





366
AAAGGCAC C CAGCACAU
4223
AUGUGCUG CUGAUGAGGCCGUUAGGCCGAA IUGCCUUU
13563





367
AAGGCACC C AGCACAUC
4224
GAUGUGCU CUGAUGAGGCCGUUAGGCCGAA IGUGCCUU
13564





368
AGGCACCC A GCACAUCA
4225
UGAUGUGC CUGAUGAGGCCGUUAGGCCGAA IGGUGCCU
13565





371
CACCCAGC A CAUCAUGC
4226
GCAUGAUG CUGAUGAGGCCGUUAGGCCGAA ICUGGGUG
13566





373
CCCAGCAC A UCAUGCAA
4227
UUGCAUGA CUGAUGAGGCCGUUAGGCCGAA IUGCUGGG
13567





376
AGCACAUC A UGCAAGCA
4228
UGCUUGCA CUGAUGAGGCCGUUAGGCCGAA IAUGUGCU
13568





380
CAUCAUGC A AGCAGGCC
4229
GGCCUGCU CUGAUGAGGCCGUUAGGCCGAA ICAUGAUG
13569





384
AUGCAAGC A GGCCAGAC
4230
GUCUGGCC CUGAUGAGGCCGUUAGGCCGAA ICUUGCAU
13570





388
AAGCAGGC C AGACACUG
4231
CAGUGUCU CUGAUGAGGCCGUUAGGCCGAA ICCUGCUU
13571





389
AGCAGGCC A GACACUGC
4232
GCAGUGUC CUGAUGAGGCCGUUAGGCCGAA IGCCUGCU
13572





393
GGCCAGAC A CUGCAUCU
4233
AGAUGCAG CUGAUGAGGCCGUUAGGCCGAA IUCUGGCC
13573





395
CCAGACAC U GCAUCUCC
4234
GGAGAUGC CUGAUGAGGCCGUUAGGCCGAA IUGUCUGG
13574





398
GACACUGC A UCUCCAAU
4235
AUUGGAGA CUGAUGAGGCCGUUAGGCCGAA ICAGUGUC
13575





401
ACUGCAUC U CCAAUGCA
4236
UGCAUUGG CUGAUGAGGCCGUUAGGCCGAA IAUGCAGU
13576





403
UGCAUCUC C AAUGCAGG
4237
CCUGCAUU CUGAUGAGGCCGUUAGGCCGAA IAGAUGCA
13577





404
GCAUCUCC A AUGCAGGG
4238
CCCUGCAU CUGAUGAGGCCGUUAGGCCGAA IGAGAUGC
13578





409
UCCAAUGC A GGGGGGAA
4239
UUCCCCCC CUGAUGAGGCCGUUAGGCCGAA ICAUUGGA
13579





420
GGGGAAGC A GCCCAUAA
4240
UUAUGGGC CUGAUGAGGCCGUUAGGCCGAA ICUUCCCC
13580





423
GAAGCAGC C CAUAAAUG
4241
CAUUUAUG CUGAUGAGGCCGUUAGGCCGAA ICUGCUUC
13581





424
AAGCAGCC C AUAAAUGG
4242
CCAUUUAU CUGAUGAGGCCGUUAGGCCGAA IGCUGCUU
13582





425
AGCAGCCC A UAAAUGGU
4243
ACCAUUUA CUGAUGAGGCCGUUAGGCCGAA IGGCUGCU
13583





435
AAAUGGUC U UUGCCUGA
4244
UCAGGCAA CUGAUGAGGCCGUUAGGCCGAA IACCAUUU
13584





440
GUCUUUGC C UGAAAUGG
4245
CCAUUUCA CUGAUGAGGCCGUUAGGCCGAA ICAAAGAC
13585





441
UCUUUGCC U GAAAUGGU
4246
ACCAUUUC CUGAUGAGGCCGUUAGGCCGAA IGCAAAGA
13586





470
CGAAAGGC U GAGCAUAA
4247
UUAUGCUC CUGAUGAGGCCGUUAGGCCGAA ICCUUUCG
13587





475
GGCUGAGC A UAACUAAA
4248
UUUAGUUA CUGAUGAGGCCGUUAGGCCGAA ICUCAGCC
13588





480
AGCAUAAC U AAAUCUGC
4249
GCAGAUUU CUGAUGAGGCCGUUAGGCCGAA IUUAUGCU
13589





486
ACUAAAUC U GCCUGUGG
4250
CCACAGGC CUGAUGAGGCCGUUAGGCCGAA IAUUUAGU
13590





489
AAAUCUGC C UGUGGAAG
4251
CUUCCACA CUGAUGAGGCCGUUAGGCCGAA ICAGAUUU
13591





490
AAUCUGCC U GUGGAAGA
4252
UCUUCCAC CUGAUGAGGCCGUUAGGCCGAA IGCAGAUU
13592





505
GAAAUGGC A AACAAUUC
4253
GAAUUGUU CUGAUGAGGCCGUUAGGCCGAA ICCAUUUC
13593





509
UGGCAAAC A AUUCUGCA
4254
UGCAGAAU CUGAUGAGGCCGUUAGGCCGAA IUUUGCCA
13594





514
AACAAUUC U GCAGUACU
4255
AGUACUGC CUGAUGAGGCCGUUAGGCCGAA IAAUUGUU
13595





517
AAUUCUGC A GUACUUUA
4256
UAAAGUAC CUGAUGAGGCCGUUAGGCCGAA ICAGAAUU
13596





522
UGCAGUAC U UUAACCUU
4257
AAGGUUAA CUGAUGAGGCCGUUAGGCCGAA IUACUGCA
13597





528
ACUUUAAC C UUGAACAC
4258
CUGUUCAA CUGAUGAGGCCGUUAGGCCGAA IUUAAAGU
13598





529
CUUUAACC U UGAACACA
4259
UGUGUUCA CUGAUGAGGCCGUUAGGCCGAA IGUUAAAG
13599





535
CCUUGAAC A CAGCUCAA
4260
UUGAGCUG CUGAUGAGGCCGUUAGGCCGAA IUUCAAGG
13600





537
UUGAACAC A GCUCAAGC
4261
GCUUGAGC CUGAUGAGGCCGUUACGCCGAA IUGUUCAA
13601





540
AACACAGC U CAAGCAAA
4262
UUUGCUUG CUGAUGAGGCCGUUAGGCCGAA ICUGUGUU
13602





542
CACAGCUC A AGCAAACC
4263
GGUUUGCU CUGAUGAGGCCGUUAGGCCGAA IAGCUGUG
13603





546
GCUCAAGC A AACCACAC
4264
GUGUGGUU CUGAUCAGGCCGUUAGGCCGAA ICUUGAGC
13604





550
AAGCAAAC C ACACUGGC
4265
GCCAGUGU CUGAUGAGGCCGUUAGGCCGAA IUUUGCUU
13605





551
AGCAAACC A CACUGGCU
4266
AGCCAGUG CUGAUGAGGCCGUUAGGCCGAA IGUUUGCU
13606





553
CAAACCAC A CUGGCUUC
4267
GAAGCCAG CUGAUGAGGCCGUUAGGCCGAA IUGGUUUG
13607





555
AACCACAC U GGCUUCUA
4268
UAGAAGCC CUGAUGAGGCCGUUAGGCCGAA IUGUGGUU
13608





559
ACACUGUC U UCUACAGC
4269
GCUGUAGA CUGAUGAGGCCGUUAGGCCGAA ICCAGUGU
13609





562
CUGGCUUC U ACAGCUGC
4270
GCAGCUGU CUGAUGAGGCCGUUAGGCCGAA IAAGCCAG
13610





565
GCUUCUAC A GCUGCAAA
4271
UUUGCAGC CUGAUGAGGCCGUUAGGCCGAA IUAGAAGC
13611





568
UCUACAGC U GCAAAUAU
4272
AUAUUUGC CUGAUGAGGCCGUUAGGCCGAA ICUGUAGA
13612





571
ACAGCUGC A AAUAUCUA
4273
UAGAUAUU CUGAUGAGGCCGUUAGGCCGAA ICAGCUGU
13613





578
CAAAUAUC U AGCUGUAC
4274
GUACAGCU CUGAUGAGGCCGUUAGGCCGAA IAUAUUUG
13614





582
UAUCUAGC U GUACCUAC
4275
GUAGGUAC CUGAUGAGGCCGUUAGGCCGAA ICUAGAUA
13615





587
AGGUGUAC C UACUUCAA
4276
UUGAAGUA CUGAUGAGGCCGUUAGGCCGAA IUACAGCU
13616





588
GCUGUACC U ACUUCAAA
4277
UUUGAAGU CUGAUGAGGCCGUUAGGCCGAA IGUACAGC
13617





591
GUACCUAC U UCAAAGAA
4278
UUCUUUGA CUGAUGAGGCCGUUAGGCCGAA IUAGGUAC
13618





594
CCUACUUC A AAGAAGAA
4279
UUCUUCUU CUGAUGAGGCCGUUAGGCCGAA IAAGUAGG
13619





609
AAGGAAAC A GAAUCUGC
4280
GCAGAUUC CUGAUGAGGCCGUUAGGCCGAA IUUUCCUU
13620





615
ACAGAAUC U GCAAUCUA
4281
UAGAUUGC CUGAUGAGGCCGUUAGGCCGAA IAUUCUGU
13621





618
GAAUCUGC A AUCUAUAU
4282
AUAUAGAU CUGAUGAGGCCGUUAGGCCGAA ICAGACUC
13622





622
CUGCAAUC U AUAUAUUU
4283
AAAUAUAU CUGAUGAGGCCGUUAGGCCGAA IAUUGCAG
13623





642
AGUGAUAC A GGUAGACC
4284
GGUCUACC CUGAUGAGGCCGUUAGGCCGAA IUAUCACU
13624





650
AGGUAGAC C UUUCGUAG
4285
CUACGAAA CUGAUGAGGCCGUUAGGCCGAA IUCUACCU
13625





651
GGUAGACC U UUCGUAGA
4286
UCUACGAA CUGAUGAGGCCGUUAGGCCGAA IGUCUACC
13626





667
AGAUGUAC A GUGAAAUC
4287
GAUUUCAC CUGAUGAGGCCGUUAGGCCGAA IUACAUCU
13627





676
GUGAAAUC C CCGAAAUU
4288
AAUUUCGG CUGAUGAGGCCGUUAGGCCGAA IAUUUCAC
13628





677
UGAAAUCC C CGAAAUUA
4289
UAAUUUCG CUGAUGAGGCCGUUAGGCCGAA IGAUUUCA
13629





678
GAAAUCCC C GAAAUUAU
4290
AUAAUUUC CUGAUGAGGCCGUUAGGCCGAA IGGAUUUC
13630





689
AAUUAUAC A CAUGACUG
4291
CAGUCAUG CUGAUGAGGCCGUUAGGCCGAA IUAUAAUU
13631





691
UUAUACAC A UGACUGAA
4292
UUCAGUCA CUGAUGAGGCCGUUAGGCCGAA IUGUAUAA
13632





696
CACAUGAC U GAAGGAAG
4293
CUUCCUUC CUGAUGAGGCCGUUAGGCCGAA IUCAUGUG
13633





710
AAGGGAGC U CGUCAUUC
4294
GAAUGACG CUGAUGAGGCCGUUAGGCCGAA ICUCCCUU
13634





715
AGCUCGUC A UUCCCUGC
4295
GCAGGGAA CUGAUGAGGCCGUUAGGCCGAA IACGAGCU
13635





719
CGUCAUUC C CUGCCGGG
4296
CCCGGCAG CUGAUGAGGCCGUUAGGCCGAA IAAUGACG
13636





720
GUCAUUCC C UGCCGGGU
4297
ACCCGGCA CUGAUGAGGCCGUUAGGCCGAA IGAAUGAC
13637





721
UCAUUCCC U GCCGGGUU
4298
AACCCGGC CUGAUGAGGCCGUUAGGCCGAA IGGAAUGA
13638





724
UUCCCUGC C GGGUUACG
4299
CGUAACCC CUGAUGAGGCCGUUAGGCCGAA ICAGGGAA
13639





735
GUUACGUC A CCUAACAU
4300
AUGUUAGG CUGAUGAGGCCGUUAGGCCGAA IACGUAAC
13640





737
UACGUCAC C UAACAUCA
4301
UGAUGUUA CUGAUGAGGCCGUUAGGCCGAA IUGACGUA
13641





738
ACGUCACC U AACAUCAC
4302
GUGAUGUU CUGAUGAGGCCGUUAGGCCGAA IGUGACGU
13642





742
CACCUAAC A UCACUGUU
4303
AACAGUGA CUGAUGAGGCCGUUAGGCCGAA IUUAGGUG
13643





745
CUUACAUC A CUGUUACU
4304
AGUAACAG CUGAUGAGGCCGUUAGGCCGAA IAUGUUAG
13644





747
AACAUCAC U GUUACUUU
4305
AAAGUAAC CUGAUGAGGCCGUUAGGCCGAA IUGAUGUU
13645





753
ACUGUGAC U UUAAAAAA
4306
UUUUUUAA CUGAUGAGGCCGUUAGGCCGAA IUAACAGU
13646





767
AAAGUUUC C ACUUGACA
4307
UGUCAAGU CUGAUGAGGCCGUUAGGCCGAA IAAACUUU
13647





768
AAGUUUCC A CUUGACAC
4308
GUGUCAAG CUGAUGAGGCCGUUAGGCCGAA IGAAACUU
13648





770
GUUUCCAC U UGACACUU
4309
AAGUGUCA CUGAUGAGGCCGUUAGGCCGAA IUGGAAAC
13649





775
CACUUGAC A CUUUGAUC
4310
GAUCAAAG CUGAUGAGGCCGUUAGGCCGAA IUCAAGUG
13650





777
CUUGACAC U UUGAUCCC
4311
GGGAUCAA CUGAUGAGGCCGUUAGGCCGAA IUGUCAAG
13651





784
CUUUGAUC C CUGAUGGA
4312
UCCAUCAG CUGAUGAGGCCGUUAGGCCGAA IAUCAAAG
13652





785
UUUGAUCC C UGAUGGAA
4313
UUCCAUCA CUGAUGAGGCCGUUAGGCCGAA IGAUCAAA
13653





786
UUGAUCCC U GAUGGAAA
4314
UUUCCAUC CUGAUGAGGCCGUUAGGCCGAA IGGAUCAA
13654





799
GAAAACGC A UAAUCUGG
4315
UCAGAUUA CUGAUGAGGCCGUUAGGCCGAA ICGUUUUC
13655





805
GCAUAAUC U GGGACAGU
4316
ACUGUCCC CUGAUGAGGCCGUUAGGCCGAA IAUUAUGC
13656





811
UCUGGGAC A GUAGAAAG
4317
CUUUCUAC CUGAUGAGGCCGUUAGGCCGAA IUCCCAGA
13657





823
GAAAGGGC U UCAUCAUA
4318
UAUGAUGA CUGAUGAGGCCGUUAGGCCGAA ICCCUUUC
13658





826
AGGGCUUC A UCAUAUCA
4319
UGAUAUGA CUGAUGAGGCCGUUAGGCCGAA IAAGCCCU
13659





829
GCUUCAUC A UAUCAAAU
4320
AUUUGAUA CUGAUGAGGCCGUUAGGCCGAA IAUGAAGC
13660





834
AUCAUAUC A AAUGCAAC
4321
GUUGCAUU CUGAUGAGGCCGUUAGGCCGAA IAUAUGAU
13661





840
UCAAAUGC A ACGUACAA
4322
UUGUACGU CUGAUGAGGCCGUUAGGCCGAA ICAGUUGA
13662





847
CAACGUAC A AAGAAAUA
4323
UAUUUCUU CUGAUGAGGCCGUUAGGCCGAA IUAGGUUG
13663





860
AAUAGGGC U UCUGACCU
4324
AGGUCAGA CUGAUGAGGCCGUUAGGCCGAA ICCCUAUU
13664





863
AGGGCUUC U GACCUGUG
4325
CACAGGUC CUGAUGAGGCCGUUAGGCCGAA IAAGCCCU
13665





867
CUUCUGAC C UGUGAAGC
4326
GCUUCACA CUGAUGAGGCCGUUAGGCCGAA IUCAGAAG
13666





868
UUCUGACC U GUGAAGCA
4327
UGCUUCAC CUGAUGAGGCCGUUAGGCCGAA IGUCAGAA
13667





876
UGUGAAGC A ACAGUCAA
4328
UUGACUGU CUGAUGAGGCCGUUAGGCCGAA ICUUCACA
13668





879
GAAGCAAC A GUCAAUGG
4329
CCAUUGAC CUGAUGAGGCCGUUAGGCCGAA IUUGCUUC
13669





883
CAACAGUC A AUGGGCAU
4330
AUGCCCAU CUGAUGAGGCCGUUAGGCCGAA IACUGUUG
13670





890
CAAUGGGC A UUUGUAUA
4331
UAUACAAA CUGAUGAGGCCGUUAGGCCGAA ICCCAUUG
13671





903
UAUAAGAC A AACUAUCU
4332
AGAUAGUU CUGAUGAGGCCGUUAGGCCGAA IUCUUAUA
13672





907
AGACAAAC U AUCUCACA
4333
UGUGAGAU CUGAUGAGGCCGUUAGGCCGAA IUUUGUCU
13673





911
AAACUAUC U CACACAUC
4334
GAUGUGUG CUGAUGAGGCCGUUAGGCCGAA IAUAGUUU
13674





913
ACUAUCUC A CACAUCGA
4335
UCGAUGUG CUGAUGAGGCCGUUAGGCCGAA IAGAUAGU
13675





915
UAUCUCAC A CAUCGACA
4336
UGUCGAUG CUGAUGAGGCCGUUAGGCCGAA IUGAGAUA
13676





917
UCUCACAC A UCGACAAA
4337
UUUGUCGA CUGAUGAGGCCGUUAGGCCGAA IUGUGAGA
13677





923
ACAUCGAC A AACCAAUA
4338
UAUUGGUU CUGAUGAGGCCGUUAGGCCGAA IUCCAUGU
13678





927
CGACAAAC C AAUACAAU
4339
AUUGUAUU CUGAUGAGGCCGUUAGGCCGAA IUUUGUCG
13679





928
GACAAACC A AUACAAUC
4340
GAUUGUAU CUGAUGAGGCCGUUAGGCCGAA IGUUUGUC
13680





933
ACCAAUAC A AUCAUAGA
4341
UCUAUGAU CUGAUGAGGCCGUUAGGCCGAA IUAUUGGU
13681





937
AUACAAUC A UAGAUGUC
4342
GACAUCUA CUGAUGAGGCCGUUAGGCCGAA IAUUGUAU
13682





946
UAGAUGUC C AAAUAAGC
4343
GCUUAUUU CUGAUGAGGCCGUUAGGCCGAA IACAUCUA
13683





947
AGAUGUCC A AAUAAGCA
4344
UGCUUAUU CUGAUGAGGCCGUUAGGCCGAA IGACAUCU
13684





955
AAAUAAGC A CACCACGC
4345
GCGUGGUG CUGAUGAGGCCGUUAGGCCGAA ICUUAUUU
13685





957
AUAAGCAC A CCACGCCC
4346
GGGCGUGG CUGAUGAGGCCGUUAGGCCGAA IUGCUUAU
13686





959
AAGCACAC C ACGCCCAG
4347
CUGGGCGU CUGAUGAGGCCGUUAGGCCGAA IUGUGCUU
13687





960
AGCACACC A CGCCCAGU
4348
ACUGGGCG CUGAUGAGGCCGUUAGGCCGAA IGUGUGCU
13688





964
CACCACGC C CAGUCAAA
4349
UUUGACUG CUGAUGAGGCCGUUAGGCCGAA ICGUGGUG
13689





965
ACCACGCC C AGUCAAAU
4350
AUUUGACU CUGAUGAGGCCGUUAGGCCGAA IGCGUGGU
13690





966
CCACGCCC A GUCAAAUU
4351
AAUUUGAC CUGAUGAGGCCGUUAGGCCGAA IGGCGUGG
13691





970
GCCCAGUC A AAUUACUU
4352
AAGUAAUU CUGAUGAGGCCGUUAGGCCGAA IACUGGGC
13692





977
CAAAUUAC U UAGAGGCC
4353
GGCCUCUA CUGAUGAGGCCGUUAGGCCGAA IUAAUUUG
13693





985
UUAGAGGC C AUACUCUU
4354
AAGAGUAU CUGAUGAGGCCGUUAGGCCGAA ICCUCUAA
13694





986
UAGAGGCC A UACUCUUG
4355
CAAGAGUA CUGAUGAGGCCGUUAGGCCGAA IGCCUCUA
13695





990
GGCCAUAC U CUUGUCCU
4356
AGGACAAG CUGAUGAGGCCGUUAGGCCGAA IUAUGGCC
13696





992
CCAUACUC U UGUCCUCA
4337
UGAGGACA CUGAUGAGGCCGUUAGGCCGAA IAGUAUGG
13697





997
CUCUUGUC C UCAAUUGU
4358
ACAAUUGA CUGAUGAGGCCGUUAGGCCGAA IACAAGAG
13698





998
UCUUGUCC U CAAUUGUA
4359
UACAAUUG CUGAUGAGGCCGUUAGGCCGAA IGACAAGA
13699





1000
UUGUCCUC A AUUGUACU
4360
AGUACAAU CUGAUGAGGCCGUUAGGCCGAA IAGGACAA
13700





1008
AAUUGUAC U GCUACCAC
4361
GUGGUAGC CUGAUGAGGCCGUUAGGCCGAA IUACAAUU
13701





1011
UGUACUGC U ACCACUCC
4362
GGAGUGGU CUGAUGAGGCCGUUAGGCCGAA ICAGUACA
13702





1014
ACUGCUAC C ACUCCCUU
4363
AAGGGAGU CUGAUGAGGCCGUUAGGCCGAA IUAGCAGU
13703





1015
CUGCUACC A CUCCCUUG
4364
CAAGGGAG CUGAUGAGGCCGUUAGGCCGAA IGUAGCAG
13704





1017
GCUACCAC U CCCUUGAA
4365
UUCAAGGG CUGAUGAGGCCGUUAGGCCGAA IUGGUAGC
13705





1019
UACCACUC C CUUGAACA
4366
UGUUCAAG CUGAUGAGGCCGUUAGGCCGAA IAGUGGUA
13706





1020
ACCACUCC C UUGAACAC
4367
GUGUUCAA CUGAUGAGGCCGUUAGGCCGAA IGAGUGGU
13707





1021
CCACUCCC U UGAACACG
4368
CGUGUUCA CUGAUGAGGCCGUUAGGCCGAA IGGAGUGG
13708





1027
CCUUGAAC A CGAGAGUU
4369
AACUCUCG CUGAUGAGGCCGUUAGGCCGAA IUUCAAGG
13709





1037
GAGAGUUC A AAUGACCU
4370
AGGUCAUU CUGAUGAGGCCGUUAGGCCGAA IAACUCUC
13710





1044
CAAAUGAC C UGGAGUUA
4371
UAACUCCA CUGAUGAGGCCGUUAGGCCGAA IUCAUUUG
13711





1045
AAAUGACC U GGAGUUAC
4372
GUAACUCC CUGAUGAGGCCGUUAGGCCGAA IGUCAUUU
13712





1054
GGAGUUAC C CUGAUGAA
4373
UUCAUCAG CUGAUGAGGCCGUUAGGCCGAA IUAACUCC
13713





1055
GAGUUACC C UGAUGAAA
4374
UUUCAUCA CUGAUGAGGCCGUUAGGCCGAA IGUAACUC
13714





1056
AGUUACCC U GAUGAAAA
4375
UUUUCAUC CUGAUGAGGCCGUUAGGCCGAA IGGUAACU
13715





1077
AAGAGAGC U UCCGUAAG
4376
CUUACGGA CUGAUGAGGCCGUUAGGCCGAA ICUCUCUU
13716





1080
AGAGCUUC C GUAAGGCG
4377
CGCCUUAC CUGAUGAGGCCGUUAGGCCGAA IAAGCUCU
13717





1099
GAAUUGAC C AAAGCAAU
4378
AUUGCUUU CUGAUGAGGCCGUUAGGCCGAA IUCAAUUC
13718





1100
AAUUGACC A AAGCAAUU
4379
AAUUGCUU CUGAUGAGGCCGUUAGGCCGAA IGUCAAUU
13719





1105
ACCAAAGC A AUUCCCAU
4380
AUGGGAAU CUGAUGAGGCCGUUAGGCCGAA ICUUUGGU
13720





1110
AGCAAUUC C CAUGCCAA
4381
UUGGCAUG CUGAUGAGGCCGUUAGGCCGAA IAAUUGCU
13721





1111
GCAAUUCC C AUGCCAAC
4382
GUUGGCAU CUGAUGAGGCCGUUAGGCCGAA IGAAUUGC
13722





1112
CAAUUCCC A UGCCAACA
4383
UGUUGGCA CUGAUGAGGCCGUUAGGCCGAA IGGAAUUG
13723





1116
UCCCAUGC C AACAUAUU
4384
AAUAUGUU CUGAUGAGGCCGUUAGGCCGAA ICAUGGGA
13724





1117
CCCAUGCC A ACAUAUUC
4385
GAAUAUGU CUGAUGAGGCCGUUAGGCCGAA IGCAUGGG
13725





1120
AUGCCAAC A UAUUCUAC
4386
GUAGAAUA CUGAUGAGGCCGUUAGGCCGAA IUUGGCAU
13726





1126
ACAUAUUC U ACAGUGUU
4387
AACACUGU CUGAUGAGGCCGUUAGGCCGAA IAAUAUGU
13727





1129
UAUUCUAC A GUGUUCUU
4388
AAGAACAC CUGAUGAGGCCGUUAGGCCGAA IUAGAAUA
13728





1136
CAGUGUUC U UACUAUUG
4389
CAAUAGUA CUGAUGAGGCCGUUAGGCCGAA IAACACUG
13729





1140
GUUCUUAC U AUUGACAA
4390
UUGUCAAU CUGAUGAGGCCGUUAGGCCGAA IUAAGAAC
13730





1147
CUAUUGAC A AAAUGCAG
4391
CUGCAUUU CUGAUGAGGCCGUUAGGCCGAA IUCAAUAG
13731





1154
CAAAAUGC A GAACAAAG
4392
CUUUGUUC CUGAUGAGGCCGUUAGGCCGAA ICAUUUUG
13732





1159
UGCAGAAC A AAGACAAA
4393
UUUGUCUU CUGAUGAGGCCGUUAGGCCGAA IUUCUGCA
13733





1165
ACAAAGAC A AAGGACUU
4394
AAGUCCUU CUGAUGAGGCCGUUAGGCCGAA IUCUUUGU
13734





1172
CAAAGGAC U UUAUACUU
4395
AAGUAUAA CUGAUGAGGCCGUUAGGCCGAA IUCCUCUG
13735





1179
CUUUAUAC U UGUCGUGU
4396
ACACGACA CUGAUGAGGCCGUUAGGCCGAA IUAUAAAG
13736





1199
GAGUGGAC C AUCAUCCA
4397
UGAAUGAU CUGAUGAGGCCGUUAGGCCGAA UUCCACUC
13737





1200
AGUGGACC A UCAUCCAA
4398
UUGAAUGA CUGAUGAGGCCGUUAGGCCGAA IGUCCACU
13738





1203
GGACCAUC A UUCAAAUC
4399
GAUUUGAA CUGAUGAGGCCGUUAGGCCGAA IAUGGUCC
13739





1207
CAUCAUUC A AAUCUGUU
4400
AACAGAUU CUGAUGAGGCCGUUAGGCCGAA IAAUGAUG
13740





1212
UUCAAAUC U GUUAACAC
4401
GUGUUAAC CUGAUGAGGCCGUUAGGCCGAA IAUUUGAA
13741





1219
CUGUUAAC A CCUCAGUG
4402
CACUGAGG CUGAUGAGGCCGUUAGGCCGAA IUUAACAG
13742





1221
GUUAACAC C UCAGUGCA
4403
UGCACUGA CUGAUGAGGCCGUUAGGCCGAA IUGUUAAC
13743





1222
UUAACACC U CAGUGCAU
4404
AUGCACUG CUGAUGAGGCCGUUAGGCCGAA IGUGUUAA
13744





1224
AACACCUC A GUGCAUAU
4405
AUAUGCAC CUGAUGAGGCCGUUAGGCCGAA IAGGUGUU
13745





1229
CUCAGUGC A UAUAUAUG
4406
CAUAUAUA CUGAUGAGGCCGUUAGGCCGAA ICACUGAG
13746





1245
GAUAAAGC A UUCAUCAC
4407
GUGAUGAA CUGAUGAGGCCGUUAGGCCGAA ICUUUAUC
13747





1249
AAGCAUUC A UCACUGUG
4408
CACAGUGA CUGAUGAGGCCGUUAGGCCGAA IAAUGCUU
13748





1252
CAUUCAUC A CUGUGAAA
4409
UUUCACAG CUGAUGAGGCCGUUAGGCCGAA IAUGAAUG
13749





1254
UUCAUCAC U GUGAAACA
4410
UGUUUCAC CUGAUGAGGCCGUUAGGCCGAA IUGAUGAA
13750





1262
UGUGAAAC A UCGAAAAC
4411
GUUUUCGA CUGAUGAGGCCGUUAGGCCGAA IUUUCACA
13751





1271
UCGAAAAC A GCAGGUGC
4412
GCACCUGC CUGAUGAGGCCGUUAGGCCGAA IUUUUCGA
13752





1274
AAAACAGC A GGUGCUUG
4413
CAAGCACC CUGAUGAGGCCGUUAGGCCGAA ICUGUUUU
13753





1280
GCAGGUGC U UGAAACCG
4414
CGGUUUCA CUGAUGAGGCCGUUAGGCCGAA ICACCUGC
13754





1287
CUUGAAAC C GUAGCUGG
4415
CCAGCUAC CUGAUGAGGCCGUUAGGCCGAA IUUUCAAG
13755





1293
ACCGUAGC U GGCAAGCG
4416
CGCUUGCC CUGAUGAGGCCGUUAGGCCGAA ICUACGGU
13756





1297
UAGCUGGC A AGCGGUCU
4417
AGACCGCU CUGAUGAGGCCGUUAGGCCGAA ICCAGCUA
13757





1305
AAGCGGUC U UACCGGCU
4418
AGCCGGUA CUGAUGAGGCCGUUAGGCCGAA IACCGCUU
13758





1309
GGUCUUAC C GGCUCUCU
4419
AGAGAGCC CUGAUGAGGCCGUUAGGCCGAA IUAAGACC
13759





1313
UUACCGGC U CUCUAUGA
4420
UCAUAGAG CUGAUGAGGCCGUUAGGCCGAA ICCGGUAA
13760





1315
ACCGGCUC U CUAUGAAA
4421
UUUCAUAG CUGAUGAGGCCGUUAGGCCGAA IAGCCGGU
13761





1317
CGGCUCUC U AUGAAAGU
4422
ACUUUCAU CUGAUGAGGCCGUUAGGCCGAA IAGAGCCG
13762





1332
GUGAAGGC A UUUCCCUC
4423
GAGGGAAA CUGAUGAGGCCGUUAGGCCGAA ICCUUCAC
13763





1337
GGCAUUUC C CUCGCCGG
4424
CCGGCGAG CUGAUGAGGCCGUUAGGCCGAA IAAAUGCC
13764





1338
GCAUUUCC C UCGCCGGA
4425
UCCGGCGA CUGAUGAGGCCGUUAGGCCGAA IGAAAUGC
13765





1339
CAUUUCCC U CGCCGGAA
4426
UUCCGGCG CUGAUGAGGCCGUUAGGCCGAA IGCAAAUC
13766





1343
UCCCUCGC C GGAAGUUG
4427
CAACUUCC CUGAUGAGGCCGUUAGGCCGAA ICGAGGGA
13767





1373
UGGGUUAC C UGCGACUG
4428
CAGUCGCA CUGAUGAGGCCGUUAGGCCGAA IUAACCCA
13768





1374
GGGUUACC U GCGACUGA
4429
UCAGUCGC CUGAUGAGGCCGUUAGGCCGAA IGUAACCC
13769





1380
CCUGCGAC U GAGAAAUC
4430
GAUUUCUC CUGAUGAGGCCGUUAGGCCGAA IUCGCAGG
13770





1389
GAGAAAUC U GCUCGCUA
4431
UAGCGAGC CUGAUGAGGCCGUUAGGCCGAA IAUUUCUC
13771





1392
AAAUCUGC U CGCUAUUU
4432
AAAUAGCG CUGAUGAGGCCGUUAGGCCGAA ICAGAUUU
13772





1396
CUGCUCGC U AUUUGACU
4433
AGUCAAAU CUGAUGAGGCCGUUAGGCCGAA ICGAGCAG
13773





1404
UAUUUGAC U CGUGGCUA
4434
UAGCCACG CUGAUGAGGCCGUUAGGCCGAA IUCAAAUA
13774





1411
CUCGUGGC U ACUCGUUA
4435
UAACGAGU CUGAUGAGGCCGUUAGGCCGAA ICCACGAG
13775





1414
GUGGCUAC U CGUUAAUU
4436
AAUUAACG CUGAUGAGGCCGUUAGGCCGAA IUAGCCAC
13776





1426
UAAUUAUC A AGGACGUA
4437
UACGUCCU CUGAUGAGGCCGUUAGGCCGAA IAUAAUUA
13777





1437
GACGUAAC U GAAGAGGA
4438
UCCUCUUC CUGAUGAGGCCGUUAGGCCGAA IUUACGUC
13778





1449
GAGGAUGC A GGGAAUUA
4439
UAAUUCCC CUGAUGAGGCCGUUAGGCCGAA ICAUCCUC
13779





1461
AAUUAUAC A AUCUUGCU
4440
AGCAAGAU CUGAUGAGGCCGUUAGGCCGAA IUAUAAUU
13780





1465
AUACAAUC U UGCUGAGC
4441
GCUCAGCA CUGAUGAGGCCGUUAGGCCGAA IAUUGUAU
13781





1469
AAUCUUGC U GAGCAUAA
4442
UUAUGCUC CUGAUGAGGCCGUUAGGCCGAA ICAAGAUU
13782





1474
UGCUGAGC A UAAAACAG
4443
CUGUUUUA CUGAUGAGGCCGUUAGGCCGAA ICUCAGCA
13783





1481
CAUAAAAC A GUCAAAUG
4444
CAUUUGAC CUGAUGAGGCCGUUAGGCCGAA IUUUUAUG
13784





1485
AAACAGUC A AAUGUGUU
4445
AACACAUU CUGAUGAGGCCGUUAGGCCGAA IACUGUUU
13785





1501
UUAAAAAC C UCACUGCC
4446
GGCAGUGA CUGAUGAGGCCGUUAGGCCGAA IUUUUUAA
13786





1502
UAAAAACC U CACUGCCA
4447
UGGCAGUG CUGAUGAGGCCGUUAGGCCGAA IGUUUUUA
13787





1504
AAAACCUC A CUGCCACU
4448
AGUGGCAG CUGAUGAGGCCGUUAGGCCGAA IAGGUUUU
13788





1506
AACCUCAC U GCCACUCU
4449
AGAGUGGC CUGAUGAGGCCGUUAGGCCGAA IUGAGGUU
13789





1509
CUCACUGC C ACUCUAAU
4450
AUUAGAGU CUGAUGAGGCCGUUAGGCCGAA ICAGUGAG
13790





1510
UCACUGCC A CUCUAAUU
4451
AAUUAGAG CUGAUGAGGCCGUUAGGCCGAA IGCAGUGA
13791





1512
ACUGCCAC U CUAAUUGU
4452
ACAAUUAG CUGAUGAGGCCGUUAGGCCGAA IUGGCAGU
13792





1514
UGCCACUC U AAUUGUCA
4453
UGACAAUU CUGAUGAGGCCGUUAGGCCGAA IAGUGGCA
13793





1522
UAAUUGUC A AUGUGAAA
4454
UUUCACAU CUGAUGAGGCCGUUAGGCCGAA IACAAUUA
13794





1532
UGUGAAAC C CCAGAUUU
4455
AAAUCUGG CUGAUGAGGCCGUUAGGCCGAA IUUUCACA
13795





1533
GUGAAACC C CAGAUUUA
4456
UAAAUCUG CUGAUGAGGCCGUUAGGCCGAA IGUUUCAC
13796





1534
UGAAACCC C AGAUUUAC
4457
GUAAAUCU CUGAUGAGGCCGUUAGGCCGAA IGGUUUCA
13797





1535
GAAACCCC A GAUUUACG
4458
CGUAAAUC CUGAUGAGGCCGUUAGGCCGAA IGGGUUUC
13798





1551
GAAAAGGC C GUGUCAUC
4459
GAUGACAC CUGAUGAGGCCGUUAGGCCGAA ICCUUUUC
13799





1557
GCCGUGUC A UCGUUUCC
4480
GGAAACGA CUGAUGAGGCCGUUAGGCCGAA IACACGGC
13800





1565
AUCGUUUC C AGACCCGG
4461
CCGGGUCU CUGAUGAGGCCGUUAGGCCGAA IAAACGAU
13801





1566
UCGUUUCC A GACCCGGC
4462
GCCGGGUC CUGAUGAGGCCGUUAGGCCGAA IGAAACGA
13802





1570
UUCCAGAC C CGGCUCUC
4463
GAGAGCCG CUGAUGAGGCCGUUAGGCCGAA IUCUGGAA
13803





1571
UCCAGACC C GGCUCUCU
4464
AGAGAGCC CUGAUGAGGCCGUUAGGCCGAA IGUCUGGA
13804





1575
GACCCGGC U CUCUACCC
4465
GGGUAGAG CUGAUGAGGCCGUUAGGCCGAA ICCGGGUC
13805





1577
CCCGGCUC U CUACCCAC
4466
GUGGGUAG CUGAUGAGGCCGUUAGGCCGAA IAGCCGGG
13806





1579
CGGCUCUC U ACCCACUG
4467
CAGUGGGU CUGAUGAGGCCGUUAGGCCGAA IAGAGCCG
13807





1582
CUCUCUAC C CACUGGGC
4468
GCCCAGUG CUGAUGAGGCCGUUAGGCCGAA IUAGAGAG
13808





1583
UCUCUACC C ACUGGGCA
4469
UGCCCAGU CUGAUGAGGCCGUUAGGCCGAA IGUAGAGA
13809





1584
CUCUACCC A CUGGGCAG
4470
CUGCCCAG CUGAUGAGGCCGUUAGGCCGAA IGGUAGAG
13810





1586
CUACCCAC U GGGCAGCA
4471
UGCUGCCC CUGAUGAGGCCGUUAGGCCGAA IUGGGUAG
13811





1591
CACUGGGC A GCAGACAA
4472
UUGUCUGC CUGAUGAGGCCGUUAGGCCGAA ICCCAGUG
13812





1594
UGGGCAGC A GACAAAUC
4473
GAUUUGUC CUGAUGAGGCCGUUAGGCCGAA ICUGCCCA
13813





1598
CAGCAGAC A AAUCCUGA
4474
UCAGGAUU CUGAUGAGGCCGUUAGGCCGAA IUCUGCUG
13814





1603
GACAAAUC C UGACUUGU
4475
ACAAGUCA CUGAUGAGGCCGUUAGGCCGAA IAUUUGUC
13815





1604
ACAAAUCC U GACUUGUA
4476
UACAAGUC CUGAUGAGGCCGUUAGGCCGAA IGAUUUGU
13816





1608
AUCCUGAC U UGUACCGC
4477
GCGGUACA CUGAUGAGGCCGUUAGGCCGAA IUCAGGAU
13817





1614
ACUUGUAC C GCAUAUGG
4478
CCAUAUGC CUGAUGAGGCCGUUAGGCCGAA IUACAAGU
13818





1617
UGUACCGC A UAUGGUAU
4479
AUACCAUA CUGAUGAGGCCGUUAGGCCGAA ICGGUACA
13819





1627
AUGGUAUC C CUCAACCU
4480
AGGUUGAG CUGAUGAGGCCGUUAGGCCGAA IAUACCAU
13820





1628
UGGUAUCC C UCAACCUA
4481
UAGGUUGA CUGAUGAGGCCGUUAGGCCGAA IGAUACCA
13821





1629
GGUAUCCC U CAACCUAC
4482
GUAGGUUG CUGAUGAGGCCGUUAGGCCGAA IGGAUACC
13822





1631
UAUCCCUC A ACCUACAA
4483
UUGUAGGU CUGAUGAGGCCGUUAGGCCGAA IAGGGAUA
13823





1634
CCCUCAAC C UACAAUCA
4484
UGAUUGUA CUGAUGAGGCCGUUAGGCCGAA IUUGAGGG
13824





1635
CCUCAACC U ACAAUCAA
4485
UUGAUUGU CUGAUGAGGCCGUUAGGCCGAA IGUUGAGG
13825





1638
CAACCUAC A AUCAAGUG
4486
CACUUGAU CUGAUGAGGCCGUUAGGCCGAA IUAGGUUG
13826





1642
CUACAAUC A AGUGGUUC
4487
GAACCACU CUGAUGAGGCCGUUAGGCCGAA IAUUGUAG
13827





1651
AGUGGUUC U GGCACCCC
4488
GGGGUGCC CUGAUGAGGCCGUUAGGCCGAA IAACCACU
13828





1655
GUUCUGGC A CCCCUGUA
4489
UACAGGGG CUGAUGAGGCCGUUAGGCCGAA ICCAGAAC
13829





1657
UCUGGCAC C CCUGUAAC
4490
GUUACAGG CUGAUGAGGCCGUUAGGCCGAA IUGCCAGA
13830





1658
CUGGCACC C CUGUAACC
4491
GGUUACAG CUGAUGAGGCCGUUAGGCCGAA IGUGCCAG
13831





1659
UGGCACCC C UGUAACCA
4492
UGGUUACA CUGAUGAGGCCGUUAGGCCGAA IGGUGCCA
13832





1660
GGCACCCC U GUAACCAU
4493
AUGGUUAC CUGAUGAGGCCGUUAGGCCGAA IGGGUGCC
13833





1666
CCUGUAAC C AUAAUCAU
4494
AUGAUUAU CUGAUGAGGCCGUUAGGCCGAA IUUACAGG
13834





1667
CUGUAACC A UAAUCAUU
4495
AAUGAUUA CUGAUGAGGCCGUUAGGCCGAA IGUUACAG
13835





1673
CCAUAAUC A UUCCGAAG
4496
CUUCGGAA CUGAUGAGGCCGUUAGGCCGAA IAUUAUGG
13836





1677
AAUCAUUC C GAAGCAAG
4497
CUUGCUUC CUGAUGAGGCCGUUAGGCCGAA IAAUGAUU
13837





1683
UCCGAAGC A AGGUGUGA
4498
UCACACCU CUGAUGAGGCCGUUAGGCCGAA ICUUCGGA
13838





1693
GGUGUGAC U UUEUUUCC
4499
GGAACAAA CUGAUGAGGCCGUUAGGCCGAA IUCACACC
13839





1701
UUUUGUUC C AAUAAUGA
4500
UCAUUAUU CUGAUGAGGCCGUUAGGCCGAA IAACAAAA
13840





1702
UUUGUUCC A AUAAUGAA
4501
UUCAUUAU CUGAUGAGGCCGUUAGGCCGAA IGAACAAA
13841





1716
GAAGAGUC C UUUAUCCU
4502
AGGAUAAA CUGAUGAGGCCGUUAGGCCGAA IACUCUUC
13842





1717
AAGAGUCC U UUAUCCUG
4503
CAGGAUAA CUGAUGAGGCCGUUAGGCCGAA IGACUCUU
13843





1723
CCUUUAUC C UGGAUGCU
4504
AGCAUCCA CUGAUGAGGCCGUUAGGCCGAA IAUAAAGG
13844





1724
CUUUAUCC U GGAUGCUG
4505
CAGCAUCC CUGAUGAGGCCGUUAGGCCGAA IGAUAAAG
13845





1731
CUGGAUGC U GACAGCAA
4506
UUGCUGUC CUGAUGAGGCCGUUAGGCCGAA ICAUCCAG
13846





1735
AUGCUGAC A GCAACAUG
4507
CAUGUUGC CUGAUGAGGCCGUUAGGCCGAA IUCAGCAU
13847





1738
CUGACAGC A ACAUGGGA
4508
UCCCAUGU CUGAUGAGGCCGUUAGGCCGAA ICUGUCAG
13848





1741
ACAGCAAC A UGGGAAAC
4509
GUUUCCCA CUGAUGAGGCCGUUAGGCCGAA IUUGCUGU
13849





1750
UGGGAAAC A GAAUUGAG
4510
CUCAAUUC CUGAUGAGGCCGUUAGGCCGAA IUUUCCCA
13850





1762
UUGAGAGC A UCACUCAG
4511
CUGAGUGA CUGAUGAGGCCGUUAGGCCGAA ICUCUCAA
13851





1765
AGAGCAUC A CUCAGCGC
4512
GCGCUGAG CUGAUGAGGCCGUUAGGCCGAA IAUGCUCU
13852





1767
AGGAUCAC U CAGCGCAU
4513
AUGCGCUG CUGAUGAGGCCGUUAGGCCGAA IUGAUGCU
13853





1769
CAUCACUC A GCGCAUGG
4514
CCAUGCGC CUGAUGAGGCCGUUAGGCCGAA IAGUGAUG
13854





1774
CUCAGCGC A UGGCAAUA
4515
UAUUGCCA CUGAUGAGGCCGUUAGGCCGAA ICGCUGAG
13855





1779
CGCAUGGC A AUAAUAGA
4516
UCUAUUAU CUGAUGAGGCCGUUAGGCCGAA ICCAUGCG
13856





1806
AAGAUGGC U AGCACCUU
4517
AAGGUGCU CUGAUGAGGCCGUUAGGCCGAA ICCAUCUU
13857





1810
UGGCUAGC A CCUUGGUU
4518
AACCAAGG CUGAUGAGGCCGUUAGGCCGAA ICUAGCCA
13858





1812
GCUAGCAC C UUGGUUGU
4519
ACAACCAA CUGAUGAGGCCGUUAGGCCGAA IUGCUAGC
13859





1813
CUAGCACC U UGGUUGUG
4520
CACAACCA CUGAUGAGGCCGUUAGGCCGAA IGUGCUAG
13860





1824
GUUGUGGC U GACUCUAG
4521
CUAGAGUC CUGAUGAGGCCGUUAGGCCGAA ICCACAAC
13861





1828
UGGCUGAC U CUAGAAUU
4522
AAUUCUAG CUGAUGAGGCCGUUAGGCCGAA IUCAGCCA
13862





1830
GCUGACUC U AGAAUUUC
4523
GAAAUUCU CUGAUGAGGCCGUUAGGCCGAA IAGUCAGC
13863





1839
AGAAUUUC U GGAAUCUA
4524
UAGAUUCC CUGAUGAGGCCGUUAGGCCGAA IAAAUUCU
13864





1846
CUGGAAUC U ACAUUUGC
4525
GCAAAUGU CUGAUGAGGCCGUUAGGCCGAA IAUUCCAG
13865





1849
GAAUCUAC A UUUGCAUA
4526
UAUGCAAA CUGAUGAGGCCGUUAGGCCGAA IUAGAUUC
13866





1855
ACAUUUGC A UAGCUUCC
4527
GGAAGCUA CUGAUGAGGCCGUUAGGCCGAA ICAAAUGU
13867





1860
UGCAUAGC U UCCAAUAA
4528
UUAUUGGA CUGAUGAGGCCGUUAGGCCGAA ICUAUGCA
13868





1863
AUAGCUUC C AAUAAAGU
4529
ACUUUAUU CUGAUGAGGCCGUUAGGCCGAA IAAGCUAU
13869





1864
UAGCUUCC A AUAAAGUU
4530
AACUUUAU CUGAUGAGGCCGUUAGGCCGAA IGAAGCUA
13870





1878
GUUGGGAC U GUGGGAAG
4531
CUUCCCAC CUGAUGAGGCCGUUAGGCCGAA IUCCCAAC
13871





1891
GAAGAAAC A UAAGCUUU
4532
AAAGCUUA CUGAUGAGGCCGUUAGGCCGAA IUUUCUUC
13872





1897
ACAUAAGC U UUUAUAUC
4533
GAUAUAAA CUGAUGAGGCCGUUAGGCCGAA ICUUAUGU
13873





1906
UUUAUAUC A CAGAUGUG
4534
CACAUCUG CUGAUGAGGCCGUUAGGCCGAA IAUAUAAA
13874





1908
UAUAUCAC A GAUGUGCC
4535
GGCACAUC CUGAUGAGGCCGUUAGGCCGAA IUGAUAUA
13875





1916
AGAUGUGC C AAAUGGGU
4536
ACCCAUUU CUGAUGAGGCCGUUAGGCCGAA ICACAUCU
13876





1917
GAUGUGCC A AAUGGGUU
4537
AACCCAUU CUGAUGAGGCCGUUAGGCCGAA IGCACAUC
13877





1928
UGGGUUUC A UGUUAACU
4538
AGUUAACA CUGAUGAGGCCGUUAGGCCGAA IAAACCCA
13878





1936
AUGUUAAC U UGGAAAAA
4539
UUUUUCCA CUGAUGAGGCCGUUAGGCCGAA IUUAACAU
13879





1949
AAAAAUGC C GACGGAAG
4540
CUUCCGUC CUGAUGAGGCCGUUAGGCCGAA ICAUUUUU
13880





1966
GAGAGGAC C UGAAACUG
4541
CAGUUUCA CUGAUGAGGCCGUUAGGCCGAA IUCCUCUC
13881





1967
AGAGGACC U GAAACUGU
4542
ACAGUUUC CUGAUGAGGCCGUUAGGCCGAA IGUCCUCU
13882





1973
CCUGAAAC U GUCUUGCA
4543
UGCAAGAC CUGAUGAGGCCGUUAGGCCGAA IUUUCAGG
13883





1977
AAACUGUC U UGCACAGU
4544
ACUGUGCA CUGAUGAGGCCGUUAGGCCGAA IACAGUUU
13884





1981
UGUCUUGC A CAGUUAAC
4545
GUUAACUG CUGAUGAGGCCGUUAGGCCGAA ICAAGACA
13885





1983
UCUUGCAC A GUUAACAA
4546
UUGUUAAC CUGAUGAGGCCGUUAGGCCGAA IUGCAAGA
13886





1990
CAGUUAAC A AGUUCUUA
4547
UAAGAACU CUGAUGAGGCCGUUAGGCCGAA IUUAACUG
13887





1996
ACAAGUUC U UAUACAGA
4548
UCUGUAUA CUGAUGAGGCCGUUAGGCCGAA IAACUUGU
13888





2002
UCUUAUAC A GAGACGUU
4549
AACGUCUC CUGAUGAGGCCGUUAGGCCGAA IUAUAAGA
13889





2013
GACGUUAC U UGGAUUUU
4550
AAAAUCCA CUGAUGAGGCCGUUAGGCCGAA IUAACGUC
13890





2024
GAUUUUAC U GCGGACAG
4551
CUGUCCGC CUGAUGAGGCCGUUAGGCCGAA IUAAAAUC
13891





2031
CUGCGGAC A GUUAAUAA
4552
UUAUUAAC CUGAUGAGGCCGUUAGGCCGAA IUCCGCAG
13892





2041
UUAAUAAC A GAACAAUG
4553
CAUUGUUC CUGAUGAGGCCGUUAGGCCGAA IUUAUUAA
13893





2046
AACAGAAC A AUGCACUA
4554
UAGUGCAU CUGAUGAGGCCGUUAGGCCGAA IUUCUGUU
13894





2051
AACAAUGC A CUACAGUA
4555
UACUGUAG CUGAUGAGGCCGUUAGGCCGAA ICAUUGUU
13895





2053
CAAUGCAC U ACAGUAUU
4556
AAUACUGU CUGAUGAGGCCGUUAGGCCGAA IUGCAUUG
13896





2056
UGCACUAC A GUAUUAGC
4557
GCUAAUAC CUGAUGAGGCCGUUAGGCCGAA IUAGUGCA
13897





2065
GUAUUAGC A AGCAAAAA
4558
UUUUUGCU CUGAUGAGGCCGUUAGGCCGAA ICUAAUAC
13898





2069
UAGCAAGC A AAAAAUGG
4559
CCAUUUUU CUGAUGAGGCCGUUAGGCCGAA ICUUGCUA
13899





2079
AAAAUGGC C AUCACUAA
4560
UUAGUGAU CUGAUGAGGCCGUUAGGCCGAA ICCAUUUU
13900





2080
AAAUGGCC A UCACUAAG
4561
CUUAGUGA CUGAUGAGGCCGUUAGGCCGAA IGCCAUUU
13901





2083
UGGCCAUC A CUAAGGAG
4562
CUCCUUAG CUGAUGAGGCCGUUAGGCCGAA IAUGGCCA
13902





2085
GCCAUCAC U AAGGAGCA
4563
UGCUCCUU CUGAUGAGGCCGUUAGGCCGAA IUGAUGGC
13903





2093
UAAGGAGC A CUCCAUCA
4564
UGAUGGAG CUGAUGAGGCCGUUAGGCCGAA ICUCCUUA
13904





2095
AGGAGCAC U CCAUCACU
4565
AGUGAUGG CUGAUGAGGCCGUUAGGCCGAA IUGCUCCU
13905





2097
GAGCACUC C AUCACUCU
4566
AGAGUGAU CUGAUGAGGCCGUUAGGCCGAA IAGUGCUC
13906





2098
AGCACUCC A UCACUCUU
4567
AAGAGUGA CUGAUGAGGCCGUUAGGCCGAA IGAGUGCU
13907





2101
ACUCCAUC A CUCUUAAU
4568
AUUAAGAG CUGAUGAGGCCGUUAGGCCGAA IAUGGAGU
13908





2103
UCCAUCAC U CUUAAUCU
4569
AGAUUAAG CUGAUGAGGCCGUUAGGCCGAA IUGAUGGA
13909





2105
CAUCACUC U UAAUCUUA
4570
UAAGAUUA CUGAUGAGGCCGUUAGGCCGAA IAGUGAUG
13910





2111
UCUUAAUC U UACCAUCA
4571
UGAUGGUA CUGAUGAGGCCGUUAGGCCGAA IAUUAAGA
13911





2115
AAUCUUAC C AUCAUGAA
4572
UUCAUGAU CUGAUGAGGCCGUUAGGCCGAA IUAAGAUU
13912





2116
AUCUUACC A UCAUGAAU
4573
AUUCAUGA CUGAUGAGGCCGUUAGGCCGAA IGUAAGAU
13913





2119
UUACCAUC A UGAAUGUU
4574
AACAUUCA CUGAUGAGGCCGUUAGGCCGAA IAUGGUAA
13914





2130
AAUGUUUC C CUGCAAGA
4575
UCUUGCAG CUGAUGAGGCCGUUAGGCCGAA IAAACAUU
13915





2131
AUGUUUCC C UGCAAGAU
4576
AUCUUGCA CUGAUGAGGCCGUUAGGCCGAA IGAAACAU
13916





2132
UGUUUCCC U GCAAGAUU
4577
AAUCUUGC CUGAUGAGGCCGUUAGGCCGAA IGGAAACA
13917





2135
UUCCCUGC A AGAUUCAG
4578
CUGAAUCU CUGAUGAGGCCGUUAGGCCGAA ICAGGGAA
13918





2142
CAAGAUUC A GGCACCUA
4579
UAGGUGCC CUGAUGAGGCCGUUAGGCCGAA IAAUCUUG
13919





2146
AUUCAGGC A CCUAUGCC
4580
GGCAUAGG CUGAUGAGGCCGUUAGGCCGAA ICCUGAAU
13920





2148
UCAGGCAC C UAUGCCUG
4581
CAGGCAUA CUGAUGAGGCCGUUAGGCCGAA IUGCCUGA
13921





2149
CAGGCACC U AUGCCUGC
4582
GCAGGCAU CUGAUGAGGCCGUUAGGCCGAA IGUGCCUG
13922





2154
ACCUAUGC C UGCAGAGC
4583
GCUCUGCA CUGAUGAGGCCGUUAGGCCGAA ICAUAGGU
13923





2155
CCUAUGCC U GCAGAGCC
4584
GGCUCUGC CUGAUGAGGCCGUUAGGCCGAA IGCAUAGG
13924





2158
AUGCCUGC A GAGCCAGG
4585
CCUGGCUC CUGAUGAGGCCGUUAGGCCGAA ICAGGCAU
13925





2163
UGCAGAGC C AGGAAUGU
4586
ACAUUCCU CUGAUGAGGCCGUUAGGCCGAA ICUCUGCA
13926





2164
GCAGAGCC A GGAAUGUA
4587
UACAUUCC CUGAUGAGGCCGUUAGGCCGAA IGCUCUGC
13927





2176
AUGUAUAC A CAGGGGAA
4588
UUCCCCUG CUGAUGAGGCCGUUAGGCCGAA IUAUACAU
13928





2178
GUAUACAC A GGGGAAGA
4589
UCUUCCCC CUGAUGAGGCCGUUAGGCCGAA IUGUAUAC
13929





2191
AAGAAAUC C UCCAGAAG
4590
CUUCUGGA CUGAUGAGGCCGUUAGGCCGAA IAUUUCUU
13930





2192
AGAAAUCC U CCAGAAGA
4591
UCUUCUGG CUGAUGAGGCCGUUAGGCCGAA IGAUUUCU
13931





2194
AAAUCCUC C AGAAGAAA
4592
UUUCUUCU CUGAUGAGGCCGUUAGGCCGAA IAGGAUUU
13932





2195
AAUCCUCC A GAAGAAAG
4593
CUUUCUUC CUGAUGAGGCCGUUAGGCCGAA IGAGGAUU
13933





2211
GAAAUUAC A AUCAGAGA
4594
UCUCUGAU CUGAUGAGGCCGUUAGGCCGAA IUAAUUUC
13934





2215
UUACAAUC A GAGAUCAG
4595
CUGAUCUC CUGAUGAGGCCGUUAGGCCGAA IAUUGUAA
13935





2222
CAGAGAUC A GGAAGCAC
4596
GUGCUUCC CUGAUGAGGCCGUUAGGCCGAA IAUCUCUG
13936





2229
CAGGAAGC A CCAUACCU
4597
AGGUAUGG CUGAUGAGGCCGUUAGGCCGAA ICUUCCUG
13937





2231
GGAAGCAC C AUACCUCC
4598
GGAGGUAU CUGAUGAGGCCGUUAGGCCGAA IUGCUUCC
13938





2232
GAAGCACC A UACCUCCU
4599
AGGAGGUA CUGAUGAGGCCGUUAGGCCGAA IGUGCUUC
13939





2236
CACCAUAC C UCCUGCGA
4600
UCGCAGGA CUGAUGAGGCCGUUAGGCCGAA IUAUGGUG
13940





2237
ACCAUACC U CCUGCGAA
4601
UUCGCAGG CUGAUGAGGCCGUUAGGCCGAA IGUAUGGU
13941





2239
CAUACCUC C UGCGAAAC
4602
GUUUCGCA CUGAUGAGGCCGUUAGGCCGAA IAGGUAUG
13942





2240
AUACCUCC U GCGAAACC
4603
GGUUUCGC CUGAUGAGGCCGUUAGGCCGAA IGAGGUAU
13943





2248
UGCGAAAC C UCAGUGAU
4604
AUCACUGA CUGAUGAGGCCGUUAGGCCGAA IUUUCGCA
13944





2249
GCGAAACC U CAGUGAUC
4605
GAUCACUG CUGAUGAGGCCGUUAGGCCGAA IGUUUCGC
13945





2251
GAAACCUC A GUGAUCAC
4606
GUGAUCAC CUGAUGAGGCCGUUAGGCCGAA IAGGUUUC
13946





2258
CAGUGAUC A CACAGUGG
4607
CCACUGUG CUGAUGAGGCCGUUAGGCCGAA IAUCACUG
13947





2260
GUGAUCAC A CACUGGCC
4608
GGCCACUG CUGAUGAGGCCGUUAGGCCGAA IUGAUCAC
13948





2262
GAUCACAC A GUGGCCAU
4609
AUGGCCAC CUGAUGAGGCCGUUAGGCCGAA IUGUGAUC
13949





2268
ACAGUGGC C AUCAGCAG
4610
CUGCUGAU CUGAUGAGGCCGUUAGGCCGAA ICCACUGU
13950





2269
CAGUGGCC A UCAGCAGU
4611
ACUGCUGA CUGAUGAGGCCGUUAGGCCGAA IGCCACUG
13951





2272
UGGCCAUC A GCAGUUCC
4612
GGAACUGC CUGAUGAGGCCGUUAGGCCGAA IAUGGCCA
13952





2275
CCAUCAGC A GUUCCACC
4613
GGUGGAAC CUGAUGAGGCCGUUAGGCCGAA ICUGAUGG
13953





2280
AGCAGUUC C ACCACUUU
4614
AAAGUGGU CUGAUGAGGCCGUUAGGCCGAA IAACUGCU
13954





2281
GCAGUUCC A CCACUUUA
4615
UAAAGUGG CUGAUGAGGCCGUUAGGCCGAA IGAACUGC
13955





2283
AGUUCCAC C ACUUUAGA
4616
UCUAAAGU CUGAUGAGGCCGUUAGGCCGAA IUGGAACU
13956





2284
GUUCCACC A CUUUAGAC
4617
GUCUAAAG CUGAUGAGGCCGUUAGGCCGAA IGUGGAAC
13957





2286
UCCACCAC U UUAGACUG
4618
CAGUCUAA CUGAUGAGGCCGUUAGGCCGAA IUGGUGGA
13958





2293
CUUUAGAC U GUCAUGCU
4619
AGCAUGAC CUGAUGAGGCCGUUAGGCCGAA IUCUAAAG
13959





2297
AGACUGUC A UGCUAAUG
4620
CAUUAGCA CUGAUGAGGCCGUUAGGCCGAA IACAGUCU
13960





2301
UGUCAUGC U AAUGGUGU
4621
ACACCAUU CUGAUGAGGCCGUUAGGCCGAA ICAUGACA
13961





2311
AUGGUGUC C CCGAGCCU
4622
AGGCUCGG CUGAUGAGGCCGUUAGGCCGAA IACACCAU
13962





2312
UGGUGUCC C CGAGCCUC
4623
GAGGCUCG CUGAUGAGGCCGUUAGGCCGAA IGACACCA
13963





2313
GGUGUCCC C GAGCCUCA
4624
UGAGGCUC CUGAUGAGGCCGUUAGGCCGAA IGGACACC
13964





2318
CCCCGAGC C UCAGAUCA
4625
UGAUCUGA CUGAUGAGGCCGUUAGGCCGAA ICUCGGGG
13965





2319
CCCGAGCC U CAGAUCAC
4626
GUGAUCUG CUGAUGAGGCCGUUAGGCCGAA IGCUCGGG
13966





2321
CGAGCCUC A GAUCACUU
4627
AAGUGAUC CUGAUGAGGCCGUUAGGCCGAA IAGGCUCG
13967





2326
CUCAGAUC A CUUGGUUU
4628
AAACCAAG CUGAUGAGGCCGUUAGGCCGAA IAUCUGAG
13968





2328
CAGAUCAC U UGGUUUAA
4629
UUAAACCA CUGAUGAGGCCGUUAGGCCGAA IUGAUCUG
13969





2341
UUAAAAAC A ACCACAAA
4630
UUUGUGGU CUGAUGAGGCCGUUAGGCCGAA IUUUUUAA
13970





2344
AAAACAAC C ACAAAAUA
4631
UAUUUUGU CUGAUGAGGCCGUUAGGCCGAA IUUGUUUU
13971





2345
AAACAACC A CAAAAUAC
4632
GUAUUUUG CUGAUGAGGCCGUUAGGCCGAA IGUUGUUU
13972





2347
ACAACCAC A AAAUACAA
4633
UUGUAUUU CUGAUGAGGCCGUUAGGCCGAA IUGGUUGU
13973





2354
CAAAAUAC A ACAAGAGC
4634
GCUCUUGU CUGAUGAGGCCGUUAGGCCGAA IUAUUUUG
13974





2357
AAUACAAC A AGAGCCUG
4635
CAGGCUCU CUGAUGAGGCCGUUAGGCCGAA IUUGUAUU
13975





2363
ACAAGAGC C UGGAAUUA
4636
UAAUUCCA CUGAUGAGGCCGUUAGGCCGAA ICUCUUGU
13976





2364
CAAGAGCC U GGAAUUAU
4637
AUAAUUCC CUGAUGAGGCCGUUAGGCCGAA IGCUCUUG
13977





2381
UUUAGGAC C AGGAAGCA
4638
UGCUUCCU CUGAUGAGGCCGUUAGGCCGAA IUCCUAAA
13978





2382
UUAGGACC A GGAAGCAG
4639
CUGCUUCC CUGAUGAGGCCGUUAGGCCGAA IGUCCUAA
13979





2389
CAGGAAGC A GCACGCUG
4640
CAGCGUGC CUGAUGAGGCCGUUAGGCCGAA ICUUCCUG
13980





2392
GAAGCAGC A CGCUGUUU
4641
AAACAGCG CUGAUGAGGCCGUUAGGCCGAA ICUGCUUC
13981





2396
CAGCACGC U GUUUAUUG
4642
CAAUAAAC CUGAUGAGGCCGUUAGGCCGAA ICGUGCUG
13982





2413
AAAGAGUC A CAGAAGAG
4643
CUCUUCUG CUGAUGAGGCCGUUAGGCCGAA IACUCUUU
13983





2415
AGAGUCAC A GAAGAGGA
4644
UCCUCUUC CUGAUGAGGCCGUUAGGCCGAA IUGACUCU
13984





2434
AAGGUGUC U AUCACUGC
4645
GCAGUGAU CUGAUGAGGCCGUUAGGCCGAA IACACCUU
13985





2438
UGUCUAUC A CUGCAAAG
4646
CUUUGCAG CUGAUGAGGCCGUUAGGCCGAA IAUAGACA
13986





2440
UCUAUCAC U GCAAAGCC
4647
GGCUUUGC CUGAUGAGGCCGUUAGGCCGAA IUGAUAGA
13987





2443
AUCACUGC A AAGCCACC
4648
GGUGGCUU CUGAUGAGGCCGUUAGGCCGAA ICAGUGAU
13988





2448
UGCAAAGC C ACCAACCA
4649
UGGUUGGU CUGAUGAGGCCGUUAGGCCGAA ICUUUGCA
13989





2449
GCAAAGCC A CCAACCAG
4650
CUGGUUGG CUGAUGAGGCCGUUAGGCCGAA IGCUUUGC
13990





2451
AAAGCCAC C AACCAGAA
4651
UUCUGGUU CUGAUGAGGCCGUUAGGCCGAA IUGGCUUU
13991





2452
AAGCCACC A ACCAGAAG
4652
CUUCUGGU CUGAUGAGGCCGUUAGGCCGAA IGUGGCUU
13992





2455
CCACCAAC C AGAAGGGC
4653
GCCCUUCU CUGAUGAGGCCGUUAGGCCGAA IUUGGUGG
13993





2456
CACCAACC A GAAGGGCU
4654
AGCCCUUC CUGAUGAGGCCGUUAGGCCGAA IGUUGGUG
13994





2464
AGAAGGGC U CUGUGGAA
4655
UUCCACAG CUGAUGAGGCCGUUAGGCCGAA ICCCUUCU
13995





2466
AAGGGCUC U GUGGAAAG
4656
CUUUCCAC CUGAUGAGGCCGUUAGGCCGAA IAGCCCUU
13996





2478
GAAAGUUC A GCAUACCU
4657
AGGUAUGC CUGAUGAGGCCGUUAGGCCGAA IAACUUUC
13997





2481
AGUUCAGC A UACCUCAC
4658
GUGAGGUA CUGAUGAGGCCGUUAGGCCGAA ICUGAACU
13998





2485
CAGCAUAC C UCACUGUU
4659
AACAGUGA CUGAUGAGGCCGUUAGGCCGAA IUAUGCUG
13999





2486
AGCAUACC U CACUGUUC
4660
GAACAGUG CUGAUGAGGCCGUUAGGCCGAA IGUAUGCU
14000





2488
CAUACCUC A CUGUUCAA
4661
UUGAACAG CUGAUGAGGCCGUUAGGCCGAA IAGGUAUG
14001





2490
UACCUCAC U GUUCAAGG
4662
CCUUGAAC CUGAUGAGGCCGUUAGGCCGAA IUGAGGUA
14002





2495
CACUGUUC A AGGAACCU
4663
AGGUUCCU CUGAUGAGGCCGUUAGGCCGAA IAACACUG
14003





2502
CAAGGAAC C UCGGACAA
4664
UUGUCCGA CUGAUGAGGCCGUUAGGCCGAA IUUCCUUG
14004





2503
AAGGAACC U CGGACAAG
4665
CUUGUCCG CUGAUGAGGCCGUUAGGCCGAA IGUUCCUU
14005





2509
CCUCGGAC A AGUCUAAU
4666
AUUAGACU CUGAUGAGGCCGUUAGGCCGAA IUCCGAGG
14006





2514
GACAAGUC U AAUCUGGA
4667
UCCAGAUU CUGAUGAGGCCGUUAGGCCGAA IACUUGUC
14007





2519
GUCUAAUC U GGAGCUGA
4668
UCAGCUCC CUGAUGAGGCCGUUAGGCCGAA IAUUAGAC
14008





2525
UCUGGAGC U GAUCACUC
4669
GAGUGAUC CUGAUGAGGCCGUUAGGCCGAA ICUCCAGA
14009





2530
AGCUGAUC A CUCUAACA
4670
UGUUAGAG CUGAUGAGGCCGUUAGGCCGAA IAUCAGCU
14010





2532
CUGAUCAC U CUAACAUG
4671
CAUGUUAG CUGAUGAGGCCGUUAGGCCGAA IUGAUCAG
14011





2534
GAUCACUC U AACAUGCA
4672
UGCAUGUU CUGAUGAGGCCGUUAGGCCGAA IAGUGAUC
14012





2538
ACUCUAAC A UGCACCUG
4673
CAGGUGCA CUGAUGAGGCCGUUAGGCCGAA IUUAGAGU
14013





2542
UAACAUGC A CCUGUGUG
4674
CACACAGG CUGAUGAGGCCGUUAGGCCGAA ICAUCUUA
14014





2544
ACAUGCAC C UGUGUGGC
4675
GCCACACA CUGAUGAGGCCGUUAGGCCGAA IUGCAUGU
14015





2545
CAUGCACC U GUGUGGCU
4676
AGCCACAC CUGAUGAGGCCGUUAGGCCGAA IGUGCAUG
14016





2553
UGUGUGGC U GCGACUCU
4677
AGAGUCGC CUGAUGAGGCCGUUAGGCCGAA ICCACACA
14017





2559
GCUGCGAC U CUCUUCUG
4678
CAGAAGAG CUGAUGAGGCCGUUAGGCCGAA IUCGCAGC
14018





2561
UGCGACUC U CUUCUGGC
4679
GCCAGAAG CUGAUGAGGCCGUUAGGCCGAA IAGUCGCA
14019





2563
CGACUCUC U UCUGGCUC
4680
GAGCCAGA CUGAUGAGGCCGUUAGGCCGAA IAGAGUCG
14020





2566
CUCUCUUC U GGCUCCUA
4681
UAGGAGCC CUGAUGAGGCCGUUAGGCCGAA IAAGAGAG
14021





2570
CUUCUGGC U CCUAUUAA
4682
UUAAUAGG CUGAUGAGGCCGUUAGGCCGAA ICCAGAAG
14022





2572
UCUGGCUC C UAUUAACC
4683
GGUUAAUA CUGAUGAGGCCGUUAGGCCGAA IAGCCAGA
14023





2573
CUGGCUCC U AUUAACCC
4684
GGGUUAAU CUGAUGAGGCCGUUAGGCCGAA IGAGCCAG
14024





2580
CUAUUAAC C CUCCUUAU
4685
AUAAGGAG CUGAUGAGGCCGUUAGGCCGAA IUUAAUAG
14025





2581
UAUUAACC C UCCUUAUC
4686
GAUAAGGA CUGAUGAGGCCGUUAGGCCGAA IGUUAAUA
14026





2582
AUUAACCC U CCUUAUCC
4687
GGAUAAGG CUGAUGAGGCCGUUAGGCCGAA IGGUUAAU
14027





2584
UAACCCUC C UUAUCCGA
4688
UCGGAUAA CUGAUGAGGCCGUUAGGCCGAA IAGGGUUA
14028





2585
AACCCUCC U UAUCCGAA
4689
UUCGGAUA CUGAUGAGGCCGUUAGGCCGAA IGAGGGUU
14029





2590
UCCUUAUC C GAAAAAUG
4690
CAUUUUUC CUGAUGAGGCCGUUAGGCCGAA IAUAAGGA
14030





2607
AAAAGGUC U UCUUCUGA
4691
UCAGAAGA CUGAUGAGGCCGUUAGGCCGAA IACCUUUU
14031





2610
AGGUCUUC U UCUGAAAU
4692
AUUUCAGA CUGAUGAGGCCGUUAGGCCGAA IAAGACCU
14032





2613
UCUUCUUC U GAAAUAAA
4693
UUUAUUUC CUGAUGAGGCCGUUAGGCCGAA IAAGAAGA
14033





2625
AUAAAGAC U GACUACCU
4694
AGGUAGUC CUGAUGAGGCCGUUAGGCCGAA IUCUUUAU
14034





2629
AGACUGAC U ACCUAUCA
4695
UGAUAGGU CUGAUGAGGCCGUUAGGCCGAA IUCAGUCU
14035





2632
CUGACUAC C UAUCAAUU
4696
AAUUGAUA CUGAUGAGGCCGUUAGGCCGAA IUAGUCAG
14036





2633
UGACUACC U AUCAAUUA
4697
UAAUUGAU CUGAUGAGGCCGUUAGGCCGAA IGUAGUCA
14037





2637
UACCUAUC A AUUAUAAU
4698
AUUAUAAU CUGAUGAGGCCGUUAGGCCGAA IAUAGGUA
14038





2650
UAAUGGAC C CAGAUGAA
4699
UUCAUCUG CUGAUGAGGCCGUUAGGCCGAA IUCCAUUA
14039





2651
AAUGGACC C AGAUGAAG
4700
CUUCAUCU CUGAUGAGGCCGUUAGGCCGAA IGUCCAUU
14040





2652
AUGGACCC A GAUGAAGU
4701
ACUUCAUC CUGAUGAGGCCGUUAGGCCGAA IGGUCCAU
14041





2663
UGAAGUUC C UUUGGAUG
4702
CAUCCAAA CUGAUGAGGCCGUUAGGCCGAA IAACUUCA
14042





2664
GAAGUUCC U UUGGAUGA
4703
UCAUCCAA CUGAUGAGGCCGUUAGGCCGAA IGAACUUC
14043





2675
GGAUGAGC A GUGUGAGC
4704
GCUCACAC CUGAUGAGGCCGUUAGGCCGAA ICUCAUCC
14044





2687
UGAGCGGC U CCCUUAUG
4705
CAUAAGGG CUGAUGAGGCCGUUAGGCCGAA ICCGCUCA
14045





2689
AGCGGCUC C CUUAUGAU
4706
AUCAUAAG CUGAUGAGGCCGUUAGGCCGAA IAGCCGCU
14046





2690
GCGGCUCC C UUAUGAUG
4707
CAUCAUAA CUGAUGAGGCCGUUAGGCCGAA IGAGCCGC
14047





2691
CGGCUCCC U UAUGAUGC
4708
GCAUCAUA CUGAUGAGGCCGUUAGGCCGAA IGGAGCCG
14048





2700
UAUGAUGC C AGCAAGUG
4709
CACUUGCU CUGAUGAGGCCGUUAGGCCGAA ICAUCAUA
14049





2701
AUGAUGCC A GCAAGUGG
4710
CCACUUGC CUGAUGAGGCCGUUAGGCCGAA IGCAUCAU
14050





2704
AUGCCAGC A AGUGGGAG
4711
CUCCCACU CUGAUGAGGCCGUUAGGCCGAA ICUGGCAU
14051





2718
GAGUUUGC C CGGGAGAG
4712
CUCUCCCG CUGAUGAGGCCGUUAGGCCGAA ICAAACUC
14052





2719
AGUUUGCC C GGGAGAGA
4713
UCUCUCCC CUGAUGAGGCCGUUAGGCCGAA IGCAAACU
14053





2729
GGAGAGAC U UAAACUGG
4714
CCAGUUUA CUGAUGAGGCCGUUAGGCCGAA IUCUCUCC
14054





2735
ACUUAAAC U GGGCAAAU
4715
AUUUGCCC CUGAUGAGGCCGUUAGGCCGAA IUUUAAGU
14055





2740
AACUGGGC A AAUCACUU
4716
AAGUGAUU CUGAUGAGGCCGUUAGGCCGAA ICCCAGUU
14056





2745
GGCAAAUC A CUUGGAAG
4717
CUUCCAAG CUGAUGAGGCCGUUAGGCCGAA IAUUUGCC
14057





2747
CAAAUCAC U UGGAAGAG
4718
CUCUUCCA CUGAUGAGGCCGUUAGGCCGAA IUGAUUUG
14058





2760
AGAGGGGC U UUUGGAAA
4719
UUUCCAAA CUGAUGAGGCCGUUAGGCCGAA ICCCCUCU
14059





2777
AGUGGUUC A AGCAUCAG
4720
CUGAUGCU CUGAUGAGGCCGUUAGGCCGAA IAACCACU
14060





2781
GUUCAAGC A UCAGCAUU
4721
AAUGCUGA CUGAUGAGGCCGUUAGGCCGAA ICUUGAAC
14061





2784
CAAGCAUC A GCAUUUGG
4722
CCAAAUGC CUGAUGAGGCCGUUAGGCCGAA IAUGCUUG
14062





2787
GCAUCAGC A UUUGGCAU
4723
AUGCCAAA CUGAUGAGGCCGUUAGGCCGAA ICUGAUGC
14063





2794
CAUUUGGC A UUAAGAAA
4724
UUUCUUAA CUGAUGAGGCCGUUAGGCCGAA ICCAAAUG
14064





2805
AAGAAAUC A CCUACGUG
4725
CACGUAGG CUGAUGAGGCCGUUAGGCCGAA IAUUUCUU
14065





2807
GAAAUCAC C UACGUGCC
4726
GGCACGUA CUGAUGAGGCCGUUAGGCCGAA IUGAUUUC
14066





2808
AAAUCACC U ACGUGCCG
4727
CGGCACGU CUGAUGAGGCCGUUAGGCCGAA IGUGAUUU
14067





2815
CUACGUGC C GGACUGUG
4728
CACAGUCC CUGAUGAGGCCGUUAGGCCGAA ICACGUAG
14068





2820
UGCCGGAC U GUGGCUGU
4729
ACAGCCAC CUGAUGAGGCCGUUAGGCCGAA IUCCGGCA
14069





2826
ACUGUGGC U GUGAAAAU
4730
AUUUUCAC CUGAUGAGGCCGUUAGGCCGAA ICCACAGU
14070





2837
GAAAAUGC U GAAAGAGG
4731
CCUCUUUC CUGAUGAGGCCGUUAGGCCGAA ICAUUUUC
14071





2850
GAGGGGGC C ACGGCCAG
4732
CUGGCCGU CUGAUGAGGCCGUUAGGCCGAA ICCCCCUC
14072





2851
AGGGGGCC A CGGCCAGC
4733
GCUGGCCG CUGAUGAGGCCGUUAGGCCGAA IGCCCCCU
14073





2856
GCCACGGC C AGCGAGUA
4734
UACUCGCU CUGAUGAGGCCGUUAGGCCGAA ICCGUGGC
14074





2857
CCACGGCC A GCGAGUAC
4735
GUACUCGC CUGAUGAGGCCGUUAGGCCGAA IGCCGUGG
14075





2866
GCGAGUAC A AAGCUCUG
4736
CAGAGCUU CUGAUGAGGCCGUUAGGCCGAA IUACUCGC
14076





2871
UACAAAGC U CUGAUGAC
4737
GUCAUCAG CUGAUGAGGCCGUUAGGCCGAA ICUUUGUA
14077





2873
CAAAGCUC U GAUGACUG
4738
CAGUCAUC CUGAUGAGGCCGUUAGGCCGAA IAGCUUUG
14078





2880
CUGAUGAC U GAGCUAAA
4739
UUUAGCUC CUGAUGAGGCCGUUAGGCCGAA IUCAUCAG
14079





2885
GACUGAGC U AAAAAUCU
4740
AGAUUUUU CUGAUGAGGCCGUUAGGCCGAA ICUCAGUC
14080





2893
UAAAAAUC U UGACCCAC
4741
GUGGGUCA CUGAUGAGGCCGUUAGGCCGAA IAUUUUUA
14081





2898
AUCUUGAC C CACAUUGG
4742
CCAAUGUG CUGAUGAGGCCGUUAGGCCGAA IUCAAGAU
14082





2899
UCUUGACC C ACAUUGGC
4743
GCCAAUGU CUGAUGAGGCCGUUAGGCCGAA IGUCAAGA
14083





2900
CUUGACCC A CAUUGGCC
4744
GGCCAAUG CUGAUGAGGCCGUUAGGCCGAA IGGUCAAG
14084





2902
UGACCCAC A UUGGCCAC
4745
GUGGCCAA CUGAUGAGGCCGUUAGGCCGAA IUGGGUCA
14085





2908
ACAUUGGC C ACCAUCUG
4746
CAGAUGGU CUGAUGAGGCCGUUAGGCCGAA ICCAAUGU
14086





2909
CAUUGGCC A CCAUCUGA
4747
UCAGAUGG CUGAUGAGGCCGUUAGGCCGAA IGCCAAUG
14087





2911
UUGGCCAC C AUCUGAAC
4748
GUUCAGAU CUGAUGAGGCCGUUAGGCCGAA IUGGCCAA
14088





2912
UGGCCACC A UCUGAACG
4749
CGUUCAGA CUGAUGAGGCCGUUAGGCCGAA IGUGGCCA
14089





2915
CCACCAUC U GAACGUGG
4750
CCACGUUC CUGAUGAGGCCGUUAGGCCGAA IAUGGUGG
14090





2929
UGGUUAAC C UGCUGGGA
4751
UCCCAGCA CUGAUGAGGCCGUUAGGCCGAA IUUAACCA
14091





2930
GGUUAACC U GCUGGGAG
4752
CUCCCAGC CUGAUGAGGCCGUUAGGCCGAA IGUUAACC
14092





2933
UAACCUGC U GGGAGCCU
4753
AGGCUCCC CUGAUGAGGCCGUUAGGCCGAA ICAGGUUA
14093





2940
CUGGGAGC C UGCACCAA
4754
UUGGUGCA CUGAUGAGGCCGUUAGGCCGAA ICUCCCAG
14094





2941
UGGGAGCC U GCACCAAG
4755
CUUGGUGC CUGAUGAGGCCGUUAGGCCGAA IGCUCCCA
14095





2944
GAGCCUGC A CCAAGCAA
4756
UUGCUUGG CUGAUGAGGCCGUUAGGCCGAA ICAGGCUC
14096





2946
GCCUGCAC C AAGCAAGG
4757
CCUUGCUU CUGAUGAGGCCGUUAGGCCGAA IUGCAGGC
14097





2947
CCUGCACC A AGCAAGGA
4758
UCCUUGCU CUGAUGAGGCCGUUAGGCCGAA IGUGCAGG
14098





2951
CACCAAGC A AGGAGGGC
4759
GCCCUCCU CUGAUGAGGCCGUUAGGCCGAA ICUUGGUG
14099





2960
AGGAGGGC C UCUGAUGG
4760
CCAUCAGA CUGAUGAGGCCGUUAGGCCGAA ICCCUCCU
14100





2961
GGAGGGCC U CUGAUGGU
4761
ACCAUCAG CUGAUGAGGCCGUUAGGCCGAA IGCCCUCC
14101





2963
AGGGCCUC U GAUGGUGA
4762
UCACCAUC CUGAUGAGGCCGUUAGGCCGAA IAGGCCCU
14102





2983
UUGAAUAC U GCAAAUAU
4763
AUAUUUGC CUGAUGAGGCCGUUAGGCCGAA IUAUUCAA
14103





2986
AAUACUGC A AAUAUGGA
4764
UCCAUAUU CUGAUGAGGCCGUUAGGCCGAA ICAGUAUU
14104





2999
UGGAAAUC U CUCCAACU
4765
AGUUGGAG CUGAUGAGGCCGUUAGGCCGAA IAUUUCCA
14105





3001
GAAAUCUC U CCAACUAC
4766
GUAGUUGG CUGAUGAGGCCGUUAGGCCGAA IAGAUUUC
14106





3003
AAUCUCUC C AACUACCU
4767
AGGUAGUU CUGAUGAGGCCGUUAGGCCGAA IAGAGAUU
14107





3004
AUCUCUCC A ACUACCUC
4768
GAGGUAGU CUGAUGAGGCCGUUAGGCCCAA IGAGAGAU
14108





3007
UCUCCAAC U ACCUCAAG
4769
CUUGAGGU CUGAUGAGGCCGUUAGGCCGAA IUUGGAGA
14109





3010
CCAACUAC C UCAAGAGC
4770
GCUCUUGA CUGAUGAGGCCGUUAGGCCGAA IUAGUUGG
14110





3011
CAACUACC U CAAGAGCA
4771
UGCUCUUG CUGAUGAGGCCGUUAGGCCGAA IGUAGUUG
14111





3013
ACUACCUC A AGAGCAAA
4772
UUUGCUCU CUGAUGAGGCCGUUAGGCCGAA IAGGUAGU
14112





3019
UCAAGAGC A AACGUGAC
4773
GUCACGUU CUGAUGAGGCCGUUAGGCCGAA ICUCUUGA
14113





3028
AACGUGAC U UAUUUUUU
4774
AAAAAAUA CUGAUGAGGCCGUUAGGCCGAA IUCACGUU
14114





3038
AUUUUUUU U CAACAAGG
4775
CCUUGUUG CUGAUGAGGCCGUUAGGCCGAA IAAAAAAU
14115





3040
UUUUUCUC A ACAAGGAU
4776
AUCCUUGU CUGAUGAGGCCGUUAGGCCGAA IAGAAAAA
14116





3043
UUCUCAAC A AGGAUGCA
4777
UGCAUCCU CUGAUGAGGCCGUUAGGCCGAA IUUGAGAA
14117





3051
AAGGAUGC A GCACUACA
4778
UGUAGUGC CUGAUGAGGCCGUUAGGCCGAA ICAUCCUU
14118





3054
GAUGCAGC A CUACACAU
4779
AUGUGUAG CUGAUGAGGCCGUUAGGCCGAA ICUGCAUC
14119





3056
UGCAGCAC U ACACAUGG
4780
CCAUGUGU CUGAUGAGGCCGUUAGGCCGAA IUGCUGCA
14120





3059
AGCACUAC A CAUGGAGC
4781
GCUCCAUG CUGAUGAGGCCGUUAGGCCGAA IUAGUGCU
14121





3061
CACUACAC A UGGAGCCU
4782
AGGCUCCA CUGAUGAGGCCGUUAGGCCGAA IUGUAGUG
14122





3068
CAUGGAGC C UAAGAAAG
4783
CUUUCUUA CUGAUGAGGCCGUUAGGCCGAA ICUCCAUG
14123





3069
AUGGAGCC U AAGAAAGA
4784
UCUUUCUU CUGAUGAGGCCGUUAGGCCGAA IGCUCCAU
14124





3089
AAUGGAGC C AGGCCUGG
4785
CCAGGCCU CUGAUGAGGCCGUUAGGCCGAA ICUCCAUU
14125





3090
AUGGAGCC A GGCCUGGA
4786
UCCAGGCC CUGAUGAGGCCGUUAGGCCGAA IGCUCCAU
14126





3094
AGCCAGGC C UGGAACAA
4787
UUGUUCCA CUGAUGAGGCCGUUAGGCCGAA ICCUGGCU
14127





3095
GCCAGGCC U GGAACAAG
4788
CUUGUUCC CUGAUGAGGCCGUUAGGCCGAA IGCCUGGC
14128





3101
CCUGGAAC A AGGCAAGA
4789
UCUUGCCU CUGAUGAGGCCGUUAGGCCGAA IUUCCAGG
14129





3106
AACAAGGC A AGAAACCA
4790
UGGUUUCU CUGAUGAGGCCGUUAGGCCGAA ICCUUGUU
14130





3113
CAAGAAAC C AAGACUAG
4791
CUAGUCUU CUGAUGAGGCCGUUAGGCCGAA IUUUCUUG
14131





3114
AAGAAACC A AGACUAGA
4792
UCUAGUCU CUGAUGAGGCCGUUAGGCCGAA IGUUUCUU
14132





3119
ACCAAGAC U AGAUAGCG
4793
CGCUAUCU CUGAUGAGGCCGUUAGGCCGAA IUCUUGGU
14133





3130
AUAGCGUC A CCAGCAGC
4794
GCUGCUGG CUGAUGAGGCCGUUAGGCCGAA IACGCUAU
14134





3132
AGCGUCAC C AGCAGCGA
4795
UCGCUGCU CUGAUGAGGCCGUUAGGCCGAA IUGACGCU
14135





3133
GCGUCACC A GCAGCGAA
4796
UUCGCUGC CUGAUGAGGCCGUUAGGCCGAA IGUGACGC
14136





3136
UCACCAGC A GCGAAAGC
4797
GCUUUCGC CUGAUGAGGCCGUUAGGCCGAA ICUGGUGA
14137





3145
GCGAAAGC U UUGCGAGC
4798
GCUCGCAA CUGAUGAGGCCGUUAGGCCGAA ICUUUCGC
14138





3154
UUGCGAGC U CCGGCUUU
4799
AAAGCCGG CUGAUGAGGCCGUUAGGCCGAA ICUCGCAA
14139





3156
GCGAGCUC C GGCUUUCA
4800
UGAAAGCC CUGAUGAGGCCGUUAGGCCGAA IAGCUCGC
14140





3160
GCUCCGGC U UUCAGGAA
4801
UUCCUGAA CUGAUGAGGCCGUUAGGCCGAA ICCGGAGC
14141





3164
CGGCUUUC A GGAAGAUA
4802
UAUCUUCC CUGAUGAGGCCGUUAGGCCGAA IAAAGCCG
14142





3179
UAAAAGUC U GAGUGAUG
4803
CAUCACUC CUGAUGAGGCCGUUAGGCCGAA IACUUUUA
14143





3207
GAGGAUUC U GACGGUUU
4804
AAACCGUC CUGAUGAGGCCGUUAGGCCGAA IAAUCCUC
14144





3217
ACGGUUUC U ACAAGGAG
4805
CUCCUUGU CUGAUGAGGCCGUUAGGCCGAA IAAACCGU
14145





3220
GUUUCUAC A AGGAGCCC
4806
GGGCUCCU CUGAUGAGGCCGUUAGGCCGAA IUAGAAAC
14146





3227
CAAGGAGC C CAUCACUA
4807
UAGUGAUG CUGAUGAGGCCGUUAGGCCGAA ICUCCUUG
14147





3228
AAGGAGCC C AUCACUAU
4808
AUAGUGAU CUGAUGAGGCCGUUAGGCCGAA IGCUCCUU
14148





3229
AGGAGCCC A UCACUAUG
4809
CAUAGUGA CUGAUGAGGCCGUUAGGCCGAA IGGCUCCU
14149





3232
AGCCCAUC A CUAUGGAA
4810
UUCCAUAG CUGAUGAGGCCGUUAGGCCGAA IAUGGGCU
14150





3234
CCCAUCAC U AUGGAAGA
4811
UCUUCCAU CUGAUGAGGCCGUUAGGCCGAA IUGAUGGG
14151





3245
GGAAGAUC U GAUUUCUU
4812
AAGAAAUC CUGAUGAGGCCGUUAGGCCGAA IAUCUUCC
14152





3252
CUGAUUUC U UACAGUUU
4813
AAACUGUA CUGAUGAGGCCGUUAGGCCGAA IAAAUCAG
14153





3256
UUUCUUAC A GUUUUCAA
4814
UUGAAAAC CUGAUGAGGCCGUUAGGCCGAA IUAAGAAA
14154





3263
CAGUUUUC A AGUGGCCA
4815
UGGCCACU CUGAUGAGGCCGUUAGGCCGAA IAAAACUG
14155





3270
CAAGUGGC C AGAGGCAU
4816
AUGCCUCU CUGAUGAGGCCGUUAGGCCGAA ICCACUUG
14156





3271
AAGUGGCC A GAGGCAUG
4817
CAUGCCUC CUGAUGAGGCCGUUAGGCCGAA IGCCACUU
14157





3277
CCAGAGGC A UGGAGUUC
4818
GAACUCCA CUGAUGAGGCCGUUAGGCCGAA ICCUCUGG
14158





3286
UGGAGUUC C UGUCUUCC
4819
GGAAGACA CUGAUGAGGCCGUUAGGCCGAA IAACUCCA
14159





3287
GGAGUUCC U GUCUUCCA
4820
UGGAAGAC CUGAUGAGGCCGUUAGGCCGAA IGAACUCC
14160





3291
UUCCUGUC U UCCAGAAA
4821
UUUCUGGA CUGAUGAGGCCGUUAGGCCGAA IACAGGAA
14161





3294
CUGUCUUC C AGAAAGUG
4822
CACUUUCU CUGAUGAGGCCGUUAGGCCGAA IAAGACAG
14162





3295
UGUCUUCC A GAAAGUGC
4823
GCACUUUC CUGAUGAGGCCGUUAGGCCGAA IGAAGACA
14163





3304
GAAAGUGC A UUCAUCGG
4824
CCGAUGAA CUGAUGAGGCCGUUAGGCCGAA ICACUUUC
14164





3308
GUGCAUUC A UCGGGACC
4825
GGUCCCGA CUGAUGAGGCCGUUAGGCCGAA IAAUGCAC
14165





3316
AUCGGGAC C UGGCAGCG
4826
CGCUGCCA CUGAUGAGGCCGUUAGGCCGAA IUCCCGAU
14166





3317
UCGGGACC U GGCAGCGA
4827
UCGCUGCC CUGAUGAGGCCGUUAGGCCGAA IGUCCCGA
14167





3321
GACCUGGC A GCGAGAAA
4828
UUUCUCGC CUGAUGAGGCCGUUAGGCCGAA ICCAGGUC
14168





3331
CGAGAAAC A UUCUUUUA
4829
UAAAAGAA CUGAUGAGGCCGUUAGGCCGAA IUUUCUCG
14169





3335
AAACAUUC U UUUAUCUG
4830
CAGAUAAA CUGAUGAGGCCGUUAGGCCGAA IAAUGUUU
14170





3342
CUUUUAUC U GAGAACAA
4831
UUGUUCUC CUGAUGAGGCCGUUAGGCCGAA IAUAAAAG
14171





3349
CUGAGAAC A ACGUGGUG
4832
CACCACGU CUGAUGAGGCCGUUAGGCCGAA IUUCUCAG
14172





3376
AUUUUGGC C UUGCCCGG
4833
CCGGGCAA CUGAUGAGGCCGUUAGGCCGAA ICCAAAAU
14173





3377
UUUUGGCC U UGCCCGGG
4834
CCCGGGCA CUGAUGAGGCCGUUAGGCCGAA IGCCAAAA
14174





3381
GGCCUUGC C CGGGAUAU
4835
AUAUCCCG CUGAUGAGGCCGUUAGGCCGAA ICAAGGCC
14175





3382
GCCUUGCC C GGGAUAUU
4836
AAUAUCCC CUGAUGAGGCCGUUAGGCCGAA IGCAAGGC
14176





3400
AUAAGAAC C CCGAUUAU
4837
AUAAUCGG CUGAUGAGGCCGUUAGGCCGAA IUUCUUAU
14177





3401
UAAGAACC C CGAUUAUG
4838
CAUAAUCG CUGAUGAGGCCGUUAGGCCGAA IGUUCUUA
14178





3402
AAGAACCC C GAUUAUGU
4839
ACAUAAUC CUGAUGAGGCCGUUAGGCCGAA IGGUUCUU
14179





3426
GGAGAUAC U CGACUUCC
4840
GGAAGUCG CUGAUGAGGCCGUUAGGCCGAA IUAUCUCC
14180





3431
UACUCGAC U UCCUCUGA
4841
UCAGAGGA CUGAUGAGGCCGUUAGGCCGAA IUCGAGUA
14181





3434
UCGACUUC C UCUGAAAU
4842
AUUUCAGA CUGAUGAGGCCGUUAGGCCGAA IAAGUCGA
14182





3435
CGACUUCC U CUGAAAUG
4843
CAUUUCAG CUGAUGAGGCCGUUAGGCCGAA IGAAGUCG
14183





3437
ACUUCCUC U GAAAUGGA
4844
UCCAUUUC CUGAUGAGGCCGUUAGGCCGAA IAGGAAGU
14184





3450
UGGAUGGC U CCCGAAUC
4845
GAUUCGGG CUGAUGAGGCCGUUAGGCCGAA ICCAUCCA
14185





3452
CAUGGCUC C CGAAUCUA
4846
UAGAUUCG CUGAUGAGGCCGUUAGGCCGAA IAGCCAUC
14186





3453
AUGGCUCC C GAAUCUAU
4847
AUAGAUUC CUGAUGAGGCCGUUAGGCCGAA IGAGCCAU
14187





3459
CCCGAAUC U AUCUUUGA
4848
UCAAAGAU CUGAUGAGGCCGUUAGGCCGAA IAUUCGGG
14188





3463
AAUCUAUC U UUGACAAA
4849
UUUGUCAA CUGAUGAGGCCGUUAGGCCGAA IAUAGAUU
14189





3469
UCUUUGAC A AAAUCUAC
4850
GUAGAUUU CUGAUGAGGCCGUUAGGCCGAA IUCAAAGA
14190





3475
ACAAAAUC U ACAGCACC
4851
GGUGCUGU CUGAUGAGGCCGUUAGGCCGAA IAUUUUGU
14191





3478
AAAUCUAC A GCACCAAG
4852
CUUGGUGC CUGAUGAGGCCGUUAGGCCGAA IUAGAUUU
14192





3481
UCUACAGC A CCAAGAGC
4853
GCUCUUGG CUGAUGAGGCCGUUAGGCCGAA ICUGUAGA
14193





3483
UACAGCAC C AAGAGCGA
4854
UCGCUCUU CUGAUGAGGCCGUUAGGCCGAA IUGCUGUA
14194





3484
ACAGCACC A AGAGCGAC
4855
GUCGCUCU CUGAUGAGGCCGUUAGGCCGAA IGUGCUGU
14195





3501
GUGUGGUC U UACGGAGU
4856
ACUCCGUA CUGAUGAGGCCGUUAGGCCGAA IACCACAC
14196





3515
AGUAUUGC U GUGGGAAA
4857
UUUCCCAC CUGAUGAGGCCGUUAGGCCGAA ICAAUACU
14197





3526
GGGAAAUC U UCUCCUUA
4858
UAAGGAGA CUGAUGAGGCCGUUAGGCCGAA IAUUUCCC
14198





3529
AAAUCUUC U CCUUAGGU
4859
ACCUAAGG CUGAUGAGGCCGUUAGGCCGAA IAAGAUUU
14199





3531
AUCUUCUC C UUAGGUGG
4860
CCACCUAA CUGAUGAGGCCGUUAGGCCGAA IAGAAGAU
14200





3532
UCUUCUCC U UAGGUGGG
4861
CCCACCUA CUGAUGAGGCCGUUAGGCCGAA IGAGAAGA
14201





3543
GGUGGGUC U CCAUACCC
4862
GGGUAUGG CUGAUGAGGCCGUUAGGCCGAA IACCCACC
14202





3545
UGGGUCUC C AUACCCAG
4863
CUGGGUAU CUGAUGAGGCCGUUAGGCCGAA IAGACCCA
14203





3546
GGGUCUCC A UACCCAGG
4864
CCUGGGUA CUGAUGAGGCCGUUAGGCCGAA IGAGACCC
14204





3550
CUCCAUAC C CAGGAGUA
4865
UACUCCUG CUGAUGAGGCCGUUAGGCCGAA IUAUGGAG
14205





3551
UCCAUACC C AGGAGUAC
4866
GUACUCCU CUGAUGAGGCCGUUAGGCCGAA IGUAUGGA
14206





3552
CCAUACCC A GGAGUACA
4867
UGUACUCC CUGAUGAGGCCGUUAGGCCGAA IGGUAUGG
14207





3560
AGGAGUAC A AAUGGAUG
4868
CAUCCAUU CUGAUGAGGCCGUUAGGCCGAA IUACUCCU
14208





3574
AUGAGGAC U UUUGCAGU
4869
ACUGCAAA CUGAUGAGGCCGUUAGGCCGAA IUCCUCAU
14209





3580
ACUUUUGC A GUCGCCUG
4870
CAGGCGAC CUGAUGAGGCCGUUAGGCCGAA ICAAAAGU
14210





3586
GCAGUCGC C UGAGGGAA
4871
UUCCCUCA CUGAUGAGGCCGUUAGGCCGAA ICGACUGC
14211





3587
CAGUCGCC U GAGGGAAG
4872
CUUCCCUC CUGAUGAGGCCGUUAGGCCGAA IGCGACUG
14212





3598
GGGAAGGC A UGAGGAUG
4873
CAUCCUCA CUGAUGAGGCCGUUAGGCCGAA ICCUUCCC
14213





3612
AUGAGAGC U CCUGAGUA
4874
UACUCAGG CUGAUGAGGCCGUUAGGCCGAA ICUCUCAU
14214





3614
GAGAGCUC C UGAGUACU
4875
AGUACUCA CUGAUGAGGCCGUUAGGCCGAA IAGCUCUC
14215





3615
AGAGCUCC U GAGUACUC
4876
GAGUACUC CUGAUGAGGCCGUUAGGCCGAA IGAGCUCU
14216





3622
CUGAGUAC U CUACUCCU
4877
AGGAGUAG CUGAUGAGGCCGUUAGGCCGAA IUACUCAG
14217





3624
GAGUACUC U ACUCCUGA
4878
UCAGGAGU CUGAUGAGGCCGUUAGGCCGAA IAGUACUC
14218





3627
UACUCUAC U CCUGAAAU
4879
AUUUCAGG CUGAUGAGGCCGUUAGGCCGAA IUAGAGUA
14219





3629
CUCUACUC C UGAAAUCU
4880
AGAUUUCA CUGAUGAGGCCGUUAGGCCGAA IAGUAGAG
14220





3630
UCUACUCC U GAAAUCUA
4881
UAGAUUUC CUGAUGAGGCCGUUAGGCCGAA IGAGUAGA
14221





3637
CUGAAAUC U AUCAGAUC
4882
GAUCUGAU CUGAUGAGGCCGUUAGGCCGAA IAUUUCAG
14222





3641
AAUCUAUC A GAUCAUGC
4883
GCAUGAUC CUGAUGAGGCCGUUAGGCCGAA IAUAGAUU
14223





3646
AUCAGAUC A UGCUGGAC
4884
GUCCAGCA CUGAUGAGGCCGUUAGGCCGAA IAUCUGAU
14224





3650
GAUCAUGC U GGACUGCU
4885
AGCAGUCC CUGAUGAGGCCGUUAGGCCGAA ICAUGAUC
14225





3655
UGCUGGAC U GCUGGCAC
4886
GUGCCAGC CUGAUGAGGCCGUUAGGCCGAA IUCCAGCA
14226





3658
UGGACUGC U GGCACAGA
4887
UCUGUGCC CUGAUGAGGCCGUUAGGCCGAA ICAGUCCA
14227





3662
CUGCUGGC A CAGAGACC
4888
GGUCUCUG CUGAUGAGGCCGUUAGGCCGAA ICCAGCAG
14228





3664
GCUGGCAC A GAGACCCA
4889
UGGGUCUC CUGAUGAGGCCGUUAGGCCGAA IUGCCAGC
14229





3670
ACAGAGAC C CAAAAGAA
4890
UUCUUUUG CUGAUGAGGCCGUUAGGCCGAA IUCUCUGU
14230





3671
CAGAGACC C AAAAGAAA
4891
UUUCUUUU CUGAUGAGGCCGUUAGGCCGAA IGUCUCUG
14231





3672
AGAGACCC A AAAGAAAG
4892
CUUUCUUU CUGAUGAGGCCGUUAGGCCGAA IGGUCUCU
14232





3683
AGAAAGGC C AAGAUUUG
4893
CAAAUCUU CUGAUGAGGCCGUUAGGCCGAA ICCUUUCU
14233





3684
GAAAGGCC A AGAUUUGC
4894
GCAAAUCU CUGAUGAGGCCGUUAGGCCGAA IGCCUUUC
14234





3693
AGAUUUGC A GAACUUGU
4895
ACAAGUUC CUGAUGAGGCCGUUAGGCCGAA ICAAAUCU
14235





3698
UGCAGAAC U UGUGGAAA
4896
UUUCCACA CUGAUGAGGCCGUUAGGCCGAA IUUCUGCA
14236





3710
GGAAAAAC U AGGUGAUU
4897
AAUCACCU CUGAUGAGGCCGUUAGGCCGAA IUUUUUCC
14237





3722
UGAUUUGC U UCAAGCAA
4898
UUUCCACA CUGAUGAGGCCGUUAGGCCGAA ICAAAUCA
14238





3725
UUUGCUUC A AGCAAAUG
4899
CAUUUGCU CUGAUGAGGCCGUUAGGCCGAA IAAGCAAA
14239





3729
CUUCAAGC A AAUGUACA
4900
UGUACAUU CUGAUGAGGCCGUUAGGCCGAA ICUUGAAG
14240





3737
AAAUGUAC A ACAGGAUG
4901
CAUCCUGU CUGAUGAGGCCGUUAGGCCGAA IUACAUUU
14241





3740
UGUACAAC A GGAUGGUA
4902
UACCAUCC CUGAUGAGGCCGUUAGGCCGAA IUUGUACA
14242





3754
GUAAAGAC U ACAUCCCA
4903
UGGGAUGU CUGAUGAGGCCGUUAGGCCGAA IUCUUUAC
14243





3757
AAGACUAC A UCCCAAUC
4904
GAUUGGGA CUGAUGAGGCCGUUAGGCCGAA IUAGUCUU
14244





3760
ACUACAUC C CAAUCAAU
4905
AUUGAUUG CUGAUGAGGCCGUUAGGCCGAA IAUGUAGU
14245





3761
CUACAUCC C AAUCAAUG
4906
CAUUGAUU CUGAUGAGGCCGUUAGGCCGAA IGAUGUAG
14246





3762
UACAUCCC A UACUGACA
4907
GCAUUGAU CUGAUGAGGCCGUUAGGCCGAA IGGAUGUA
14247





3766
UCCCAAUC A AUGCCAUA
4908
UAUGGCAU CUGAUGAGGCCGUUAGGCCGAA IAUUGGGA
14248





3771
AUCAAUGC C AUACUGAC
4909
GUCAGUAU CUGAUGAGGCCGUUAGGCCGAA ICAUUGAU
14249





3772
UCAAUGCC A UACUGACA
4910
UGUCAGUA CUGAUGAGGCCGUUAGGCCGAA IGCAUUGA
14250





3776
UGCCAUAC U GACAGGAA
4911
UUCCUGUC CUGAUGAGGCCGUUAGGCCGAA IUAUGGCA
14251





3780
AUACUGAC A GGAAAUAG
4912
CUAUUUCC CUGAUGAGGCCGUUAGGCCGAA IUCAGUAU
14252





3798
GGGUUUAC A UACUCAAC
4913
GUUGAGUA CUGAUGAGGCCGUUAGGCCGAA IUAAACCC
14253





3802
UUACAUAC U CAACUCCU
4914
AGGAGUUG CUGAUGAGGCCGUUAGGCCGAA IUAUGUAA
14254





3804
ACAUACUC A ACUCCUGC
4915
GCAGGAGU CUGAUGAGGCCGUUAGGCCGAA IAGUAUGU
14255





3807
UACUCAAC U CCUGCCUU
4916
AAGGCAGG CUGAUGAGGCCGUUAGGCCGAA IUUGAGUA
14256





3809
CUCAACUC C UGCCUUCU
4917
AGAAGGCA CUGAUGAGGCCGUUAGGCCGAA IAGUUGAG
14257





3810
UCAACUCC U GCCUUCUC
4918
GAGAAGGC CUGAUGAGGCCGUUAGGCCGAA IGAGUUGA
14258





3813
ACUCCUGC C UUCUUUGA
4919
UCAGAGAA CUGAUGAGGCCGUUAGGCCGAA ICAGGAGU
14259





3814
CUCCUGCC U UCUCUGAG
4920
CUCAGAGA CUGAUGAGGCCGUUAGGCCGAA IGCAGGAG
14260





3817
CUGCCUUC U CUGAGGAC
4921
GUCCUCAG CUGAUGAGGCCGUUAGGCCGAA IAAGGCAG
14261





3819
GCCUUCUC U GAGGACUU
4922
AAGUCCUC CUGAUGAGGCCGUUAGGCCGAA IAGAAGGC
14262





3826
CUGAGGAC U UCUUCAGG
4923
CUUGAAGA CUGAUGAGGCCGUUAGGCCGAA IUCCUCAG
14263





3829
AGGACUUC U UCAAGGAA
4924
UUCCUUGA CUGAUGAGGCCGUUAGGCCGAA IAAGUCCU
14264





3832
ACUUCUUC A AGGAAAGU
4925
ACUUUCCU CUGAUGAGGCCGUUAGGCCGAA IAAGAAGU
14265





3846
AGUAUUUC A GCUCCGAA
4926
UUCGGAGC CUGAUGAGGCCGUUAGGCCGAA IAAAUACU
14266





3849
AUUUCAGC U CCGAAGUU
4927
AACUUCGG CUGAUGAGGCCGUUAGGCCGAA ICUGAAAU
14267





3851
UUCAGCUC C GAAGUUUA
4928
UAAACUUC CUGAUGAGGCCGUUAGGCCGAA IAGCUGAA
14268





3864
UUUAAUUC A GGAAGCUC
4929
GAGCUUCC CUGAUGAGGCCGUUAGGCCGAA IAAUUAAA
14269





3871
CAGGAAGC U CUGAUGAU
4930
AUCAUCAG CUGAUGAGGCCGUUAGGCCGAA ICUUCCUG
14270





3873
GGAAGCUC U GAUGAUGU
4931
ACAUCAUC CUGAUGAGGCCGUUAGGCCGAA IAGCUUCC
14271





3883
AUGAUGUC A GAUAUGUA
4932
UACAUAUC CUGAUGAGGCCGUUAGGCCGAA IACAUCAU
14272





3897
GUAAAUGC U UUCAAGUU
4933
AACUUGAA CUGAUGAGGCCGUUAGGCCGAA ICAUUUAC
14273





3901
AUGCUUUC A AGUUCAUG
4934
CAUGAACU CUGAUGAGGCCGUUAGGCCGAA IAAAGCAU
14274





3907
UCAAGUUC A UGAGCCUG
4935
CAGGCUCA CUGAUGAGGCCGUUAGGCCGAA IAACUUGA
14275





3913
UCAUGAGC C UGGAAAGA
4936
UCUUUCCA CUGAUGAGGCCGUUAGGCCGAA ICUCAUGA
14276





3914
CAUGAGCC U GGAAAGAA
4937
UUCUUUCC CUGAUGAGGCCGUUAGGCCGAA IGCUCAUG
14277





3925
AAAGAAUC A AAACCUUU
4938
AAAGGUUU CUGAUGAGGCCGUUAGGCCGAA IAUUCUUU
14278





3930
AUCAAAAC C UUUGAAGA
4939
UCUUCAAA CUGAUGAGGCCGUUAGGCCGAA IUUUUGAU
14279





3931
UCAAAACC U UUGAAGAA
4940
UUCUUCAA CUGAUGAGGCCGUUAGGCCGAA IGUUUUGA
14280





3941
UGAAGAAC U UUUACCGA
4941
UCGGUAAA CUGAUGAGGCCGUUAGGCCGAA IUUCUUCA
14281





3947
ACUUUUAC C GAAUGCCA
4942
UGGCAUUC CUGAUGAGGCCGUUAGGCCGAA IUAAAAGU
14282





3954
CCGAAUGC C ACCUCCAU
4943
AUGGAGGU CUGAUGAGGCCGUUAGGCCGAA ICAUUCGG
14283





3955
CGAAUGCC A CCUCCAUG
4944
CAUGGAGG CUGAUGAGGCCGUUAGGCCGAA IGCAUUCG
14284





3957
AAUGCCAC C UCCAUGUU
4945
AACAUGGA CUGAUGAGGCCGUUAGGCCGAA IUGGCAUU
14285





3958
AUGCCACC U CCAUGUUU
4946
AAACAUGG CUGAUGAGGCCGUUAGGCCGAA IGUGGCAU
14286





3960
GCCACCUC C AUGUUUGA
4947
UCAAACAU CUGAUGAGGCCGUUAGGCCGAA IAGGUGGC
14287





3961
CCACCUCC A UGUUUGAU
4948
AUCAAACA CUGAUGAGGCCGUUAGGCCGAA IGAGGUGG
14288





3973
UUGAUGAC U ACCAGGGC
4949
GCCCUGGU CUGAUGAGGCCGUUAGGCCGAA IUCAUCAA
14289





3976
AUGACUAC C AGGGCGAC
4950
GUCGCCCU CUGAUGAGGCCGUUAGGCCGAA IUAGUCAU
14290





3977
UGACUACC A GGGCGACA
4951
UGUCGCCC CUGAUGAGGCCGUUAGGCCGAA IGUAGUCA
14291





3985
AGGGCGAC A GCAGCACU
4952
AGUGCUGC CUGAUGAGGCCGUUAGGCCGAA IUCGCCCU
14292





3988
GCGACAGC A GCACUCUG
4953
CAGAGUGC CUGAUGAGGCCGUUAGGCCGAA ICUGUCGC
14293





3991
ACAGCAGC A CUCUGUUG
4954
CAACAGAG CUGAUGAGGCCGUUAGGCCGAA ICUGCUGU
14294





3993
AGCAGCAC U CUGUUGGC
4955
GCCAACAG CUGAUGAGGCCGUUAGGCCGAA IUGCUGCU
14295





3995
CAGCACUC U GUUGGCCU
4956
AGGCCAAC CUGAUGAGGCCGUUAGGCCGAA IAGUGCUG
14296





4002
CUGUUGGC C UCUCCCAU
4957
AUGGGAGA CUGAUGAGGCCGUUAGGCCGAA ICCAACAG
14297





4003
UGUUGGCC U CUCCCAUG
4958
CAUGGGAG CUGAUGAGGCCGUUAGGCCGAA IGCCAACA
14298





4005
UUGGCCUC U CCCAUGCU
4959
AGCAUGGG CUGAUGAGGCCGUUAGGCCGAA IAGGCCAA
14299





4007
GGCCUCUC C CAUGCUGA
4960
UCAGCAUG CUGAUGAGGCCGUUAGGCCGAA IAGAGGCC
14300





4008
GCCUCUCC C AUGCUGAA
4961
UUCAGCAU CUGAUGAGGCCGUUAGGCCGAA IGAGAGGC
14301





4009
CCUCUCCC A UGCUGAAG
4962
CUUCAGCA CUGAUGAGGCCGUUAGGCCGAA IGGAGAGG
14302





4013
UCCCAUGC U GAAGCGCU
4963
AGCGCUUC CUGAUGAGGCCGUUAGGCCGAA ICAUGGGA
14303





4021
UGAAGCGC U UCACCUGG
4964
CCAGGUGA CUGAUGAGGCCGUUAGGCCGAA ICGCUUCA
14304





4024
AGCGCUUC A CCUGGACU
4965
AGUCCAGG CUGAUGAGGCCGUUAGGCCGAA IAAGCGCU
14305





4026
CGCUUCAC C UGGACUGA
4966
UCAGUCCA CUGAUGAGGCCGUUAGGCCGAA IUGAAGCG
14306





4027
GCUUCACC U GGACUGAC
4967
GUCAGUCC CUGAUGAGGCCGUUAGGCCGAA IGUGAAGC
14307





4032
ACCUGGAC U GACAGCAA
4968
UUGCUGUC CUGAUGAGGCCGUUAGGCCGAA IUCCAGGU
14308





4036
GGACUGAC A GCAAACCC
4969
GGGUUUGC CUGAUGAGGCCGUUAGGCCGAA IUCAGUCC
14309





4039
CUGACAGC A AACCCAAG
4970
CUUGGGUU CUGAUGAGGCCGUUAGGCCGAA ICUGUCAG
14310





4043
CAGCAAAC C CAAGGCCU
4971
AGGCCUUG CUGAUGAGGCCGUUAGGCCGAA IUUUGCUG
14311





4044
AGCAAACC C AAGGCCUC
4972
GAGGCCUU CUGAUGAGGCCGUUAGGCCGAA IGUUUGCU
14312





4045
GCAAACCC A AGGCCUCG
4973
CGAGGCCU CUGAUGAGGCCGUUAGGCCGAA IGGUUUGC
14313





4050
CCCAAGGC C UCGCUCAA
4974
UUGAGCGA CUGAUGAGGCCGUUAGGCCGAA ICCUUGGG
14314





4051
CCAAGGCC U CGCUCAAG
4975
CUUGAGCG CUGAUGAGGCCGUUAGGCCGAA IGCCUUGG
14315





4055
GGCCUCGC U CAAGAUUG
4976
CAAUCUUG CUGAUGAGGCCGUUAGGCCGAA ICGAGGCC
14316





4057
CCUCGCUC A AGAUUGAC
4977
GUCAAUCU CUGAUGAGGCCGUUAGGCCGAA IAGCGAGG
14317





4066
AGAUUGAC U UGAGAGUA
4978
UACUCUCA CUGAUGAGGCCGUUAGGCCGAA IUCAAUCU
14318





4077
AGAGUAAC C AGUAAAAG
4979
CUUUUACU CUGAUGAGGCCGUUAGGCCGAA IUUACUCU
14319





4078
GAGUAACC A GUAAAAGU
4980
ACUUUUAC CUGAUGAGGCCGUUAGGCCGAA IGUUACUC
14320





4100
GUCGGGGC U GUCUGAUG
4981
CAUCAGAC CUGAUGAGGCCGUUAGGCCGAA ICCCCGAC
14321





4104
GGGCUGUC U GAUGUCAG
4982
CUGACAUC CUGAUGAGGCCGUUAGGCCGAA IACAGCCC
14322





4111
CUGAUGUC A GCAGGCCC
4983
GGGCCUGC CUGAUGAGGCCGUUAGGCCGAA IACAUCAG
14323





4114
AUGUCAGC A GGCCCAGU
4984
ACUGGGCC CUGAUGAGGCCGUUAGGCCGAA ICUGACAU
14324





4118
CAGCAGGC C CAGUUUCU
4985
AGAAACUG CUGAUGAGGCCGUUAGGCCGAA ICCUGCUG
14325





4119
AGCAGGCC C AGUUUCUG
4986
CAGAAACU CUGAUGAGGCCGUUAGGCCGAA IGCCUGCU
14326





4120
GCAGGCCC A GUUUCUGC
4987
GCAGAAAC CUGAUGAGGCCGUUAGGCCGAA IGGCCUGC
14327





4126
CCAGUUUC U GCCAUUCC
4988
GGAAUGGC CUGAUGAGGCCGUUAGGCCGAA IAAACUGG
14328





4129
GUUUCUGC C AUUCCAGC
4989
GCUGGAAU CUGAUGAGGCCGUUAGGCCGAA ICAGAAAC
14329





4130
UUUCUGCC A UUCCAGCU
4990
AGCUGGAA CUGAUGAGGCCGUUAGGCCGAA IGCAGAAA
14330





4134
UGCCAUUC C AGCUGUGG
4991
CCACAGCU CUGAUGAGGCCGUUAGGCCGAA IAAUGGCA
14331





4135
GCCAUUCC A GCUGUGGG
4992
CCCACAGC CUGAUGAGGCCGUUAGGCCGAA IGAAUGGC
14332





4138
AUUCCAGC U GUGGGCAC
4993
GUGCCCAC CUGAUGAGGCCGUUAGGCCGAA ICUGGAAU
14333





4145
CUGUGGGC A CGUCAGCG
4994
CGCUGACG CUGAUGAGGCCGUUAGGCCGAA ICCCACAG
14334





4150
GGCACGUC A GCGAAGGC
4995
GCCUUCGC CUGAUGAGGCCGUUAGGCCGAA IACGUGCC
14335





4159
GCGAAGGC A AGCGCAGG
4996
CCUGCGCU CUGAUGAGGCCGUUAGGCCGAA ICCUUCGC
14336





4165
GCAAGCGC A GGUUCACC
4997
GGUGAACC CUGAUGAGGCCGUUAGGCCGAA ICGCUUGC
14337





4171
GCAGGUUC A CCUACGAC
4998
GUCGUAGG CUGAUGAGGCCGUUAGGCCGAA IAACCUGC
14338





4173
AGGUUCAC C UACGACCA
4999
UGGUCGUA CUGAUGAGGCCGUUAGGCCGAA IUGAACCU
14339





4174
GGUUCACC U ACGACCAC
5000
GUGGUCGU CUGAUGAGGCCGUUAGGCCGAA IGUGAACC
14340





4180
CCUACGAC C ACGCUGAG
5001
CUCAGCGU CUGAUGAGGCCGUUAGGCCGAA IUCGUAGG
14341





4181
CUACGACC A CGCUGAGC
5002
GCUCAGCG CUGAUGAGGCCGUUAGGCCGAA IGUCGUAG
14342





4185
GACCACGC U GAGCUGGA
5003
UCCAGCUC CUGAUGAGGCCGUUAGGCCGAA ICGUGGUC
14343





4190
CGCUGAGC U GGAAAGGA
5004
UCCUUUCC CUGAUGAGGCCGUUAGGCCGAA ICUCAGCG
14344





4210
UCGCGUGC U GCUCCCCG
5005
CGGGGAGC CUGAUGAGGCCGUUAGGCCGAA ICACGCGA
14345





4213
CGUGCUGC U CCCCGCCC
5006
GGGCGGGG CUGAUGAGGCCGUUAGGCCGAA ICAGCACG
14346





4215
UGCUGCUC C CCGCCCCC
5007
GGGGGCGG CUGAUGAGGCCGUUAGGCCGAA IAGCAGCA
14347





4216
GCUGCUCC C CGCCCCCA
5008
UGGGGGCG CUGAUGAGGCCGUUAGGCCGAA IGAGCAGC
14348





4217
CUGCUCCC C GCCCCCAG
5009
CUGGGGGC CUGAUGAGGCCGUUAGGCCGAA IGGAGCAG
14349





4220
CUCCCCGC C CCCAGACU
5010
AGUCUGGG CUGAUGAGGCCGUUAGGCCGAA ICGGGGAG
14350





4221
UCCCCGCC C CCAGACUA
5011
UAGUCUGG CUGAUGAGGCCGUUAGGCCGAA IGCGGGGA
14351





4222
CCCCGCCC C CAGACUAC
5012
GUAGUCUG CUGAUGAGGCCGUUAGGCCGAA IGGCGGGG
14352





4223
CCCGCCCC C AGACUACA
5013
UGUAGUCU CUGAUGAGGCCGUUAGGCCGAA IGGGCGGG
14353





4224
CCGCCCCC A GACUACAA
5014
UUGUAGUC CUGAUGAGGCCGUUAGGCCGAA IGGGGCGG
14354





4228
CCCCAGAC U ACAACUCG
5015
CGAGUUGU CUGAUGAGGCCGUUAGGCCGAA IUCUGGGG
14355





4231
CAGACUAC A ACUCGGUG
5016
CACCGAGU CUGAUGAGGCCGUUAGGCCGAA IUAGUCUG
14356





4234
ACUACAAC U CGGUGGUC
5017
GACCACCG CUGAUGAGGCCGUUAGGCCGAA IUUGUAGU
14357





4243
CGGUGGUC C UGUACUCC
5018
GGAGUACA CUGAUGAGGCCGUUAGGCCGAA IACCACCG
14358





4244
GGUGGUCC U GUACUCCA
5019
UGGAGUAC CUGAUGAGGCCGUUAGGCCGAA IGACCACC
14359





4249
UCCUGUAC U CCACCCCA
5020
UGGGGUGG CUGAUGAGGCCGUUAGGCCGAA IUACAGGA
14360





4251
CUGUACUC C ACCCCACC
5021
GGUGGGGU CUGAUGAGGCCGUUAGGCCGAA IAGUACAG
14361





4252
UGUACUCC A CCCCACCC
5022
GGGUGGGG CUGAUGAGGCCGUUAGGCCGAA IGAGUACA
14362





4254
UACUCCAC C CCACCCAU
5023
AUGGGUGG CUGAUGAGGCCGUUAGGCCGAA IUGGAGUA
14363





4255
ACUCCACC C CACCCAUC
5024
GAUGGGUG CUGAUGAGGCCGUUAGGCCGAA IGUGGAGU
14364





4256
CUCCACCC C ACCCAUCU
5025
AGAUGGGU CUGAUGAGGCCGUUAGGCCGAA IGGUGGAG
14365





4257
UCCACCCC A CCCAUCUA
5026
UAGAUGGG CUGAUGAGGCCGUUAGGCCGAA IGGGUGGA
14366





4259
CACCCCAC C CAUCUAGA
5027
UCUAGAUG CUGAUGAGGCCGUUAGGCCGAA IUGGGGUG
14367





4260
ACCCCACC C AUCUAGAG
5028
CUCUAGAU CUGAUGAGGCCGUUAGGCCGAA IGUGGGGU
14368





4261
CCCCACCC A UCUAGAGU
5029
ACUCUAGA CUGAUGAGGCCGUUAGGCCGAA IGGUGGGG
14369





4264
CACCCAUC U AGAGUUUG
5030
CAAACUCU CUGAUGAGGCCGUUAGGCCGAA IAUGGGUG
14370





4275
AGUUUGAC A CGAAGCCU
5031
AGGCUUCG CUGAUGAGGCCGUUAGGCCGAA IUCAAACU
14371





4282
CACGAAGC C UUAUUUCU
5032
AGAAAUAA CUGAUGAGGCCGUUAGGCCGAA ICUUCGUG
14372





4283
ACGAAGCC U UAUUUCUA
5033
UAGAAAUA CUGAUGAGGCCGUUAGGCCGAA IGCUUCGU
14373





4290
CUUAUUUC U AGAAGCAC
5034
GUGCUUCU CUGAUGAGGCCGUUAGGCCGAA IAAAUAAG
14374





4297
CUAGAAGC A CAUGUGUA
5035
UACACAUG CUGAUGAGGCCGUUAGGCCGAA ICUUCUAG
14375





4299
AGAAGCAC A UGUGUAUU
5036
AAUACACA CUGAUGAGGCCGUUAGGCCGAA IUGCUUCU
14376





4313
AUUUAUAC C CCCAGGAA
5037
UUCCUGGG CUGAUGAGGCCGUUAGGCCGAA IUAUAAAU
14377





4314
UUUAUACC C CCAGGAAA
5038
UUUCCUGG CUGAUGAGGCCGUUAGGCCGAA IGUAUAAA
14378





4315
UUAUACCC C CAGGAAAC
5039
GUUUCCUG CUGAUGAGGCCGUUAGGCCGAA IGGUAUAA
14379





4316
UAUACCCC C AGGAAACU
5040
AGUUUCCU CUGAUGAGGCCGUUAGGCCGAA IGGGUAUA
14380





4317
AUACCCCC A GGAAACUA
5041
UAGUUUCC CUGAUGAGGCCGUUAGGCCGAA IGGGGUAU
14381





4324
CAGGAAAC U AGCUUUUG
5042
CAAAAGCU CUGAUGAGGCCGUUAGGCCGAA IUUUCCUG
14382





4328
AAACUAGC U UUUGCCAG
5043
CUGGCAAA CUGAUGAGGCCGUUAGGCCGAA ICUAGUUU
14383





4334
GCUUUUGC C AGUAUUAU
5044
AUAAUACU CUGAUGAGGCCGUUAGGCCGAA ICAAAAGC
14384





4335
CUUUUGCC A GUAUUAUG
5045
CAUAAUAC CUGAUGAGGCCGUUAGGCCGAA IGCAAAAG
14385





4345
UAUUAUGC A UAUAUAAG
5046
CUUAUAUA CUGAUGAGGCCGUUAGGCCGAA ICAUAAUA
14386





4359
AAGUUUAC A CCUUUAUC
5047
GAUAAAGG CUGAUGAGGCCGUUAGGCCGAA IUAAACUU
14387





4361
GUUUACAC C UUUAUCUU
5048
AAGAUAAA CUGAUGAGGCCGUUAGGCCGAA IUGUAAAC
14388





4362
UUUACACC U UUAUCUUU
5049
AAAGAUAA CUGAUGAGGCCGUUAGGCCGAA IGUGUAAA
14389





4368
CCUUUAUC U UUCCAUGG
5050
CCAUGGAA CUGAUGAGGCCGUUAGGCCGAA IAUAAAGG
14390





4372
UAUCUUUC C AUGGGAGC
5051
GCUCCCAU CUGAUGAGGCCGUUAGGCCGAA IAAAGAUA
14391





4373
AUCUUUCC A UGGGAGCC
5052
GGCUCCCA CUGAUGAGGCCGUUAGGCCGAA IGAAAGAU
14392





4381
AUGGGAGC C AGCUGCUU
5053
AAGCAGCU CUGAUGAGGCCGUUAGGCCGAA ICUCCCAU
14393





4382
UGGGAGCC A GCUGCUUU
5054
AAAGCAGC CUGAUGAGGCCGUUAGGCCGAA IGCUCCCA
14394





4385
GAGCCAGC U GCUUUUUG
5055
CAAAAAGC CUGAUGAGGCCGUUAGGCCGAA ICUGGCUC
14395





4388
CCAGCUGC U UUUUGUGA
5056
UCACAAAA CUGAUGAGGCCGUUAGGCCGAA ICAGCUGG
14396





4412
AAUAGUGC U UUUUUUUU
5057
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA ICACUAUU
14397





4426
UUUUUGAC U AACAAGAA
5058
UUCUUGUU CUGAUGAGGCCGUUAGGCCGAA IUCAAAAA
14398





4430
UGACUAAC A AGAAUGUA
5059
UACAUUCU CUGAUGAGGCCGUUAGGCCGAA IUUAGUCA
14399





4441
AAUGUAAC U CCAGAUAG
5060
CUAUCUGG CUGAUGAGGCCGUUAGGCCGAA IUUACAUU
14400





4443
UGUAACUC C AGAUAGAG
5061
CUCUAUCU CUGAUGAGGCCGUUAGGCCGAA IAGUUACA
14401





4444
GUAACUCC A GAUAGAGA
5062
UCUCUAUC CUGAUGAGGCCGUUAGGCCGAA IGAGUUAC
14402





4462
AUAGUGAC A AGUGAAGA
5063
UCUUCACU CUGAUGAGGCCGUUAGGCCGAA IUCACUAU
14403





4473
UGAAGAAC A CUACUGCU
5064
AGCAGUAG CUGAUGAGGCCGUUAGGCCGAA IUUCUUCA
14404





4475
AAGAACAC U ACUGCUAA
5065
UUAGCAGU CUGAUGAGGCCGUUAGGCCGAA IUGUUCUU
14405





4478
AACACUAC U GCUAAAUC
5066
GAUUUAGC CUGAUGAGGCCGUUAGGCCGAA IUAGUGUU
14406





4481
ACUACUGC U AAAUCCUC
5067
GAGGAUUU CUGAUGAGGCCGUUAGGCCGAA ICAGUAGU
14407





4487
GCUAAAUC C UCAUGUUA
5068
UAACAUGA CUGAUGAGGCCGUUAGGCCGAA IAUUUAGC
14408





4488
CUAAAUCC U CAUGUUAC
5069
GUAACAUG CUGAUGAGGCCGUUAGGCCGAA IGAUUUAG
14409





4490
AAAUCCUC A UGUUACUC
5070
GAGUAACA CUGAUGAGGCCGUUAGGCCGAA IAGGAUUU
14410





4497
CAUGUUAC U CAGUGUUA
5071
UAACACUG CUGAUGAGGCCGUUAGGCCGAA IUAACAUG
14411





4499
UGUUACUC A GUGUUAGA
5072
UCUAACAC CUGAUGAGGCCGUUAGGCCGAA IAGUAACA
14412





4514
GAGAAAUC C UUCCUAAA
5073
UUUAGGAA CUGAUGAGGCCGUUAGGCCGAA IAUUUCUC
14413





4515
AGAAAUCC U UCCUAAAC
5074
GUUUAGGA CUGAUGAGGCCGUUAGGCCGAA IGAUUUCU
14414





4518
AAUCCUUC C UAAACCCA
5075
UUGGGUUA CUGAUGAGGCCGUUAGGCCGAA IAAGGAUU
14415





4519
AUCCUUCC U AAACCCAA
5076
UUGGGUUU CUGAUGAGGCCGUUAGGCCGAA IGAAGGAU
14416





4524
UCCUAAAC C CAAUGACU
5077
AGUCAUUG CUGAUGAGGCCGUUAGGCCGAA IUUUAGGA
14417





4525
CCUAAACC C AAUGACUU
5078
AAGUCAUU CUGAUGAGGCCGUUAGGCCGAA IGUUUAGG
14418





4526
CUAAACCC A AUGACUUC
5079
GAAGUCAU CUGAUGAGGCCGUUAGGCCGAA IGGUUUAG
14419





4532
CCAAUGAC U UCCCUGCU
5080
AGCAGGGA CUGAUGAGGCCGUUAGGCCGAA IUCAUUGG
14420





4535
AUGACUUC C CUGGUCCA
5081
UGGAGCAG CUGAUGAGGCCGUUAGGCCGAA IAAGUCAU
14421





4536
UGACUUCC C UGCUCCAA
5082
UUGGAGCA CUGAUGAGGCCGUUAGGCCGAA IGAAGUCA
14422





4537
GACUUCCC U GCUCCAAC
5083
GUUGGAGC CUGAUGAGGCCGUUAGGCCGAA IGGAAGUC
14423





4540
UUCCCUGC U CCAACCCC
5084
GGGGUUGG CUGAUGAGGCCGUUAGGCCGAA ICAGGGAA
14424





4542
CCCUGCUC C AACCCCCG
5085
CGGGGGUU CUGAUGAGGCCGUUAGGCCGAA IAGCAGGG
14425





4543
CCUGCUCC A ACCCCCGC
5086
GCGGGGGU CUGAUGAGGCCGUUAGGCCGAA IGAGCAGG
14426





4546
GCUCCAAC C CCCGCCAC
5087
GUGGCGGG CUGAUGAGGCCGUUAGGCCGAA IUUGGAGC
14427





4547
CUCCAACC C CCGCCACC
5088
GGUGGCGG CUGAUGAGGCCGUUAGGCCGAA IGUUGGAG
14428





4548
UCCAACCC C CGCCACCU
5089
AGGUGGCG CUGAUGAGGCCGUUAGGCCGAA IGGUUGGA
14429





4549
CCAACCCC C GCCACCUC
5090
GAGGUGGC CUGAUGAGGCCGUUAGGCCGAA IGGGUUGG
14430





4552
ACCCCCGC C ACCUCAGG
5091
CCUGAGGU CUGAUGAGGCCGUUAGGCCGAA ICGGGGGU
14431





4553
CCCCCGCC A CCUCAGGG
5092
CCCUGAGG CUGAUGAGGCCGUUAGGCCGAA IGCGGGGG
14432





4555
CCCGCCAC C UCAGGGCA
5093
UGCCCUGA CUGAUGAGGCCGUUAGGCCGAA IUGGCGGG
14433





4556
CCGCCACC U CAGGGCAC
5094
GUGCCCUG CUGAUGAGGCCGUUAGGCCGAA IGUGGCGG
14434





4558
GCCACCUC A GGGCACGC
5095
GCGUGCCC CUGAUGAGGCCGUUAGGCCGAA IAGGUGGC
14435





4563
CUCAGGGC A CGCAGGAC
5096
GUCCUGCG CUGAUGAGGCCGUUAGGCCGAA ICCCUGAG
14436





4567
GGGCACGC A GGACCAGU
5097
ACUGGUCC CUGAUGAGGCCGUUAGGCCGAA ICGUGCCC
14437





4572
CGCAGGAC C AGUUUGAU
5098
AUCAAACU CUGAUGAGGCCGUUAGGCCGAA IUCCUGCG
14438





4573
GCAGGACC A GUUUGAUU
5099
AAUCAAAC CUGAUGAGGCCGUUAGGCCGAA IGUCCUGG
14439





4589
UGAGGAGC U GCACUGAU
5100
AUCAGUGC CUGAUGAGGCCGUUAGGCCGAA ICUCCUCA
14440





4592
GGAGCUGC A CUGAUCAC
5101
GUGAUCAG CUGAUGAGGCCGUUAGGCCGAA ICAGCUCC
14441





4594
AGCUGCAC U GAUCACCC
5102
GGGUGAUC CUGAUGAGGCCGUUAGGCCGAA IUGCAGCU
14442





4599
CACUGAUC A CCCAAUGC
5103
GCAUUGGG CUGAUGAGGCCGUUAGGCCGAA IAUCAGUG
14443





4601
CUGAUCAC C CAAUGCAU
5104
AUGCAUUG CUGAUGAGGCCGUUAGGCCGAA IUGAUCAG
14444





4602
UGAUCACC C AAUGCAUC
5105
GAUGCAUU CUGAUGAGGCCGUUAGGCCGAA IGUGAUCA
14445





4603
GAUCACCC A AUGCAUCA
5106
UGAUGCAU CUGAUGAGGCCGUUAGGCCGAA IGGUGAUC
14446





4608
CCCAAUGC A UCACGUAC
5107
GUACGUGA CUGAUGAGGCCGUUAGGCCGAA ICAUUGGG
14447





4611
AAUGCAUC A CGUACCCC
5108
GGGGUACG CUGAUGAGGCCGUUAGGCCGAA IAUGCAUU
14448





4617
UCACGUAC C CCACUGGG
5109
CCCAGUGG CUGAUGAGGCCGUUAGGCCGAA IUACGUGA
14449





4618
CACGUACC C CACUGGGC
5110
GCCCAGUG CUGAUGAGGCCGUUAGGCCGAA IGUACGUG
14450





4619
ACGUACCC C ACUGGGCC
5111
GGCCCAGU CUGAUGAGGCCGUUAGGCCGAA IGGUACGU
14451





4620
CGUACCCC A CUGGGCCA
5112
UGGCCCAG CUGAUGAGGCCGUUAGGCCGAA IGGGUACG
14452





4622
UACCCCAC U GGGCCAGC
5113
GCUGGCCC CUGAUGAGGCCGUUAGGCCGAA IUGGGGUA
14453





4627
CACUGGGC C AGCCCUGC
5114
GCAGGGCU CUGAUGAGGCCGUUAGGCCGAA ICCCAGUG
14454





4628
ACUGGGCC A GCCCUGCA
5115
UGCAGGGC CUGAUGAGGCCGUUAGGCCGAA IGCCCAGU
14455





4631
GGGCCAGC C CUGCAGCC
5116
GGCUGCAG CUGAUGAGGCCGUUAGGCCGAA ICUGGCCC
14456





4632
GGCCAGCC C UGCAGCCC
5117
GGGCUGCA CUGAUGAGGCCGUUAGGCCGAA IGCUGGCC
14457





4633
GCCAGCCC U GCAGCCCA
5118
UGGGCUGC CUGAUGAGGCCGUUAGGCCGAA IGGCUGGC
14458





4636
AGCCCUGC A GCCCAAAA
5119
UUUUGGGC CUGAUGAGGCCGUUAGGCCGAA ICAGGGCU
14459





4639
CCUGCAGC C CAAAACCC
5120
GGGUUUUG CUGAUGAGGCCGUUAGGCCGAA ICUGCAGG
14460





4640
CUGCAGCC C AAAACCCA
5121
UGGGUUUU CUGAUGAGGCCGUUAGGCCGAA IGCUGCAG
14461





4641
UGCAGCCC A AAACCCAG
5122
CUGGGUUU CUGAUGAGGCCGUUAGGCCGAA IGGCUGCA
14462





4646
CCCAAAAC C CAGGGCAA
5123
UUGCCCUG CUGAUGAGGCCGUUAGGCCGAA IUUUUGGG
14463





4647
CCAAAACC C AGGGCAAC
5124
GUUGCCCU CUGAUGAGGCCGUUAGGCCGAA IGUUUUGG
14464





4648
CAAAACCC A GGGCAACA
5125
UGUUGCCC CUGAUGAGGCCGUUAGGCCGAA IGGUUUUG
14465





4653
CCCAGGGC A ACAAGCCC
5126
GGGCUUGU CUGAUGAGGCCGUUAGGCCGAA ICCCUGGG
14466





4656
AGGGCAAC A AGCCCGUU
5127
AACGGGCU CUGAUGAGGCCGUUAGGCCGAA IUUGCCCU
14467





4660
CAACAAGC C CGUUAGCC
5128
GGCUAACG CUGAUGAGGCCGUUAGGCCGAA ICUUGUUG
14468





4661
AACAAGCC C GUUAGCCC
5129
GGGCUAAC CUGAUGAGGCCGUUAGGCCGAA IGCUUGUU
14469





4668
CCGUUAGC C CCAGGGGA
5130
UCCCCUGG CUGAUGAGGCCGUUAGGCCGAA ICUAACGG
14470





4669
CGUUAGCC C CAGGGGAU
5131
AUCCCCUG CUGAUGAGGCCGUUAGGCCGAA IGCUAACG
14471





4670
GUUAGCCC C AGGGGAUC
5132
GAUCCCCU CUGAUGAGGCCGUUAGGCCGAA IGGCUAAC
14472





4671
UUAGCCCC A GGGGAUCA
5133
UGAUCCCC CUGAUGAGGCCGUUAGGCCGAA IGGGCUAA
14473





4679
AGGGGAUC A CUGGCUGG
5134
CCAGCCAG CUGAUGAGGCCGUUAGGCCGAA IAUCCCCU
14474





4681
GGGAUCAC U GGCUGGCC
5135
GGCCAGCC CUGAUGAGGCCGUUAGGCCGAA IUGAUCCC
14475





4685
UCACUGGC U GGCCUGAG
5136
CUCAGGCC CUGAUGAGGCCGUUAGGCCGAA ICCAGUGA
14476





4689
UGGCUGGC C UGAGCAAC
5137
GUUGCUCA CUGAUGAGGCCGUUAGGCCGAA ICCAGCCA
14477





4690
GGCUGGCC U GAGCAACA
5138
UGUUGCUC CUGAUGAGGCCGUUAGGCCGAA IGCCAGCC
14478





4695
GCCUGAGC A ACAUCUCG
5139
CGAGAUGU CUGAUGAGGCCGUUAGGCCGAA ICUCAGGC
14479





4698
UGAGCAAC A UCUCGGGA
5140
UCCCGAGA CUGAUGAGGCCGUUAGGCCGAA IUUGCUCA
14480





4701
GCAACAUC U CGGGAGUC
5141
GACUCCCG CUGAUGAGGCCGUUAGGCCGAA IAUGUUGC
14481





4710
CGGGAGUC C UCUAGCAG
5142
CUGCUAGA CUGAUGAGGCCGUUAGGCCGAA IACUCCCG
14482





4711
GGGAGUCC U CUAGCAGG
5143
CCUGCUAG CUGAUGAGGCCGUUAGGCCGAA IGACUCCC
14483





4713
GAGUCCUC U AGCAGGCC
5144
GGCCUGCU CUGAUGAGGCCGUUAGGCCGAA IAGGACUC
14484





4717
CCUCUAGC A GGCCUAAG
5145
CUUAGGCC CUGAUGAGGCCGUUAGGCCGAA ICUAGAGG
14485





4721
UAGCAGGC C UAAGACAU
5146
AUGUCUUA CUGAUGAGGCCGUUAGGCCGAA ICCUGCUA
14486





4722
AGCAGGCC U AAGACAUG
5147
CAUGUCUU CUGAUGAGGCCGUUAGGCCGAA IGCCUGCU
14487





4728
CCUAAGAC A UGUGAGGA
5148
UCCUCACA CUGAUGAGGCCGUUAGGCCGAA IUCUUAGG
14488





4754
AAAAAAGC A AAAAGCAA
5149
UUGCUUUU CUGAUGAGGCCGUUAGGCCGAA ICUUUUUU
14489





4761
CAAAAAGC A AGGGAGAA
5150
UUCUCCCU CUGAUGAGGCCGUUAGGCCGAA ICUUUUUG
14490





4779
AGAGAAAC C GGGAGAAG
5151
CUUCUCCC CUGAUGAGGCCGUUAGGCCGAA IUUUCUCU
14491





4790
GAGAAGGC A UGAGAAAG
5152
CUUUCUCA CUGAUGAGGCCGUUAGGCCGAA ICCUUCUC
14492





4811
UGAGACGC A CCAUGUGG
5153
CCACAUGG CUGAUGAGGCCGUUAGGCCGAA ICGUCUCA
14493





4813
AGACGCAC C AUGUGGGC
5154
GCCCACAU CUGAUGAGGCCGUUAGGCCGAA IUGCGUCU
14494





4814
GACGCACC A UGUGGGCA
5155
UGCCCACA CUGAUGAGGCCGUUAGGCCGAA IGUGCGUC
14495





4822
AUGUGGGC A CGGAGGGG
5156
CCCCUCCG CUGAUGAGGCCGUUAGGCCGAA ICCCACAU
14496





4839
GACGGGGC U CAGCAAUG
5157
CAUUGCUG CUGAUGAGGCCGUUAGGCCGAA ICCCCGUC
14497





4841
CGGGGCUC A GCAAUGCC
5158
GGCAUUGC CUGAUGAGGCCGUUAGGCCGAA IAGCCCCG
14498





4844
GGCUCAGC A AUGCCAUU
5159
AAUGGCAU CUGAUGAGGCCGUUAGGCCGAA ICUGAGCC
14499





4849
AGCAAUGC C AUUUCAGU
5160
ACUGAAAU CUGAUGAGGCCGUUAGGCCGAA ICAUUGCU
14500





4850
GCAAUGCC A UUUCAGUG
5161
CACUGAAA CUGAUGAGGCCGUUAGGCCGAA IGCAUUGC
14501





4855
GCCAUUUC A GUGGCUUC
5162
GAAGCCAC CUGAUGAGGCCGUUAGGCCGAA IAAAUGGC
14502





4861
UCAGUGGC U UCCCAGCU
5163
AGCUGGGA CUGAUGAGGCCGUUAGGCCGAA ICCACUGA
14503





4864
GUGGCUUC C CAGCUCUG
5164
CAGAGCUG CUGAUGAGGCCGUUAGGCCGAA IAAGCCAC
14504





4865
UGGCUUCC C AGCUCUGA
5165
UCAGAGCU CUGAUGAGGCCGUUAGGCCGAA IGAAGCCA
14505





4866
GGCUUCCC A GCUCUGAC
5166
GUCAGAGC CUGAUGAGGCCGUUAGGCCGAA IGGAAGCC
14506





4869
UUCCCAGC U CUGACCCU
5167
AGGGUCAG CUGAUGAGGCCGUUAGGCCGAA ICUGGGAA
14507





4871
CCCAGCUC U GACCCUUC
5168
GAAGGGUC CUGAUGAGGCCGUUAGGCCGAA IAGCUGGG
14508





4875
GCUCUGAC C CUUCUACA
5169
UGUAGAAG CUGAUGAGGCCGUUAGGCCGAA IUCAGAGC
14509





4876
CUCUGACC C UUCUACAU
5170
AUGUAGAA CUGAUGAGGCCGUUAGGCCGAA IGUCAGAG
14510





4877
UCUGACCC U UCUACAUU
5171
AAUGUAGA CUGAUGAGGCCGUUAGGCCGAA IGGUCAGA
14511





4880
GACCCUUC U ACAUUUGA
5172
UCAAAUGU CUGAUGAGGCCGUUAGGCCGAA IAAGGGUC
14512





4883
CCUUCUAC A UUUGAGGG
5173
CCCUCAAA CUGAUGAGGCCGUUAGGCCGAA IUAGAAGG
14513





4893
UUGAGGGC C CAGCCAGG
5174
CCUGGCUG CUGAUGAGGCCGUUAGGCCGAA ICCCUCAA
14514





4894
UGAGGGCC C AGCCAGGA
5175
UCCUGGCU CUGAUGAGGCCGUUAGGCCGAA IGOCCUCA
14515





4895
GAGGGCCC A GCCAGGAG
5176
CUCCUGGC CUGAUGAGGCCGUUAGGCCGAA IGGCCCUC
14516





4898
GGCCCAGC C AGGAGCAG
5177
CUGCUCCU CUGAUGAGGCCGUUAGGCCGAA ICUGGGCC
14517





4899
GCCCAGCC A GGAGCAGA
5178
UCUGCUCC CUGAUGAGGCCGUUAGGCCGAA IGCUGGGC
14518





4905
CCAGGAGC A GAUGGACA
5179
UGUCCAUC CUGAUGAGGCCGUUAGGCCGAA ICUCCUGG
14519





4913
AGAUGGAC A GCGAUGAG
5180
CUCAUCGC CUGAUGAGGCCGUUAGGCCGAA IUCCAUCU
14520





4927
GAGGGGAC A UUUUCUGG
5181
CCAGAAAA CUGAUGAGGCCGUUAGGCCGAA IUCCCCUC
14521





4933
ACAUUUUC U GGAUUCUG
5182
CAGAAUCC CUGAUGAGGCCGUUAGGCCGAA IAAAAUGU
14522





4940
CUGGAUUC U GGGAGGCA
5183
UGCCUCCC CUGAUGAGGCCGUUAGGCCGAA IAAUCCAG
14523





4948
UGGGAGGC A AGAAAAGG
5184
CCUUUUCU CUGAUGAGGCCGUUAGGCCGAA ICCUCCCA
14524





4959
AAAAGGAC A AAUAUCUU
5185
AAGAUAUU CUGAUGAGGCCGUUAGGCCGAA IUCCUUUU
14525





4966
CAAAUAUC U UUUUUGGA
5186
UCCAAAAA CUGAUGAGGCCGUUAGGCCGAA IAUAUUUG
14526





4977
UUUGGAAC U AAAGCAAA
5187
UUUGCUUU CUGAUGAGGCCGUUAGGCCGAA IUUCCAAA
14527





4983
ACUAAAGC A AAUUUUAG
5188
CUAAAAUU CUGAUGAGGCCGUUAGGCCGAA ICUUUAGU
14528





4994
UUUUAGAC C UUUACCUA
5189
UAGGUAAA CUGAUGAGGCCGUUAGGCCGAA IUCUAAAA
14529





4995
UUUAGACC U UUACCUAU
5190
AUAGGUAA CUGAUGAGGCCGUUAGGCCGAA IGUCUAAA
14530





5000
ACCUUUAC C UAUGGAAG
5191
CUUCCAUA CUGAUGAGGCCGUUAGGCCGAA IUAAAGGU
14531





5001
CCUUUACC U AUGGAAGU
5192
ACUUCCAU CUGAUGAGGCCGUUAGGCCGAA IGUAAAGG
14532





5015
AGUGGUUC U AUGUCCAU
5193
AUGGACAU CUGAUGAGGCCGUUAGGCCGAA IAACCACU
14533





5021
UCUAUGUC C AUUCUCAU
5194
AUGAGAAU CUGAUGAGGCCGUUAGGCCGAA IACAUAGA
14534





5022
CUAUGUCC A UUCUCAUU
5195
AAUGAGAA CUGAUGAGGCCGUUAGGCCGAA IGACAUAG
14535





5026
GUCCAUUC U CAUUCGUG
5196
CACGAAUG CUGAUGAGGCCGUUAGGCCGAA IAAUGGAC
14536





5028
CCAUUCUC A UUCGUGGC
5197
GCCACGAA CUGAUGAGGCCGUUAGGCCGAA IAGAAUGG
14537





5037
UUCGUGGC A UGUUUUGA
5198
UCAAAACA CUGAUGAGGCCGUUAGGCCGAA ICCACGAA
14538





5054
UUUGUAGC A CUGAGGGU
5199
ACCCUCAG CUGAUGAGGCCGUUAGGCCGAA ICUACAAA
14539





5056
UGUAGCAC U GAGGGUGG
5200
CCACCCUC CUGAUGAGGCCGUUAGGCCGAA IUGCUACA
14540





5066
AGGGUGGC A CUCAACUC
5201
GAGUUGAG CUGAUGAGGCCGUUAGGCCGAA ICCACCCU
14541





5068
GGUGGCAC U CAACUCUG
5202
CAGAGUUG CUGAUGAGGCCGUUAGGCCGAA IUGCCACC
14542





5070
UGGCACUC A ACUCUGAG
5203
CUCAGAGU CUGAUGAGGCCGUUAGGCCGAA IAGUGCCA
14543





5073
CACUCAAC U CUGAGCCC
5204
GGGCUCAG CUGAUGAGGCCGUUAGGCCGAA IUUGAGUG
14544





5075
CUCAACUC U GAGCCCAU
5205
AUGGGCUC CUGAUGAGGCCGUUAGGCCGAA IAGUUGAG
14545





5080
CUCUGAGC C CAUACUUU
5206
AAAGUAUG CUGAUGAGGCCGUUAGGCCGAA ICUCAGAG
14546





5081
UCUGAGCC C AUACUUUU
5207
AAAAGUAU CUGAUGAGGCCGUUAGGCCGAA IGCUCAGA
14547





5082
CUGAGCCC A UACUUUUG
5208
CAAAAGUA CUGAUGAGGCCGUUAGGCCGAA IGGCUCAG
14548





5086
GCCCAUAC U UUUGGCUC
5209
GAGCCAAA CUGAUGAGGCCGUUAGGCCGAA IUAUGGGC
14549





5093
CUUUUGGC U CCUCUAGU
5210
ACUAGAGG CUGAUGAGGCCGUUAGGCCGAA ICCAAAAG
14550





5095
UUUGGCUC C UCUAGUAA
5211
UUACUAGA CUGAUGAGGCCGUUAGGCCGAA IAGCCAAA
14551





5096
UUGGCUCC U CUAGUAAG
5212
CUUACUAG CUGAUGAGGCCGUUAGGCCGAA IGAGCCAA
14552





5098
GGCUCCUC U AGUAAGAU
5213
AUCUUACU CUGAUGAGGCCGUUAGGCCGAA IAGGAGCC
14553





5109
UAAGAUGC A CUGAAAAC
5214
GUUUUCAG CUGAUGAGGCCGUUAGGCCGAA ICAUCUUA
14554





5111
AGAUGCAC U GAAAACUU
5215
AAGUUUUC CUGAUGAGGCCGUUAGGCCGAA IUGCAUCU
14555





5118
CUGAAAAC U UAGCCAGA
5216
UCUGGCUA CUGAUGAGGCCGUUAGGCCGAA IUUUUCAG
14556





5123
AACUUAGC C AGAGUUAG
5217
CUAACUCU CUGAUGAGGCCGUUAGGCCGAA ICUAAGUU
14557





5124
ACUUAGCC A GAGUUAGG
5218
CCUAACUC CUGAUGAGGCCGUUAGGCCGAA IGCUAAGU
14558





5138
AGGUUGUC U CCAGGCCA
5219
UGGCCUGG CUGAUGAGGCCGUUAGGCCGAA IACAACCU
14559





5140
GUUGUCUC C AGGCCAUG
5220
CAUGGCCU CUGAUGAGGCCGUUAGGCCGAA IAGACAAC
14560





5141
UUGUCUCC A GGCCAUGA
5221
UCAUGGCC CUGAUGAGGCCGUUAGGCCGAA IGAGACAA
14561





5145
CUCCAGGC C AUGAUGGC
5222
GCCAUCAU CUGAUGAGGCCGUUAGGCCGAA ICCUGGAG
14562





5146
UCCAGGCC A UGAUGGCC
5223
GGCCAUCA CUGAUGAGGCCGUUAGGCCGAA IGCCUGGA
14563





5154
AUGAUGGC C UUACACUG
5224
CAGUGUAA CUGAUGAGGCCGUUAGGCCGAA ICCAUCAU
14564





5155
UGAUGGCC U UACACUGA
5225
UCAGUGUA CUGAUGAGGCCGUUAGGCCGAA IGCCAUCA
14565





5159
GGCCUUAC A CUGAAAAU
5226
AUUUUCAG CUGAUGAGGCCGUUAGGCCGAA IUAAGGCC
14566





5161
CCUUACAC U GAAAAUGU
5227
ACAUUUUC CUGAUGAGGCCGUUAGGCCGAA IUGUAAGG
14567





5171
AAAAUGUC A CAUUCUAU
5228
AUAGAAUG CUGAUGAGGCCGUUAGGCCGAA IACAUUUU
14568





5173
AAUGUCAC A UUCUAUUU
5229
AAAUAGAA CUGAUGAGGCCGUUAGGCCGAA IUGACAUU
14569





5177
UCACAUUC U AUUUUGGG
5230
CCCAAAAU CUGAUGAGGCCGUUAGGCCGAA IAAUGUGA
14570





5201
AUAUAGUC C AGACACUU
5231
AAGUGUCU CUGAUGAGGCCGUUAGGCCGAA IACUAUAU
14571





5202
UAUAGUCC A GACACUUA
5232
UAAGUGUC CUGAUGAGGCCGUUAGGCCGAA IGACUAUA
14572





5206
GUCCAGAC A CUUAACUC
5233
GAGUUAAG CUGAUGAGGCCGUUAGGCCGAA IUCUGGAC
14573





5208
CCAGACAC U UAACUCAA
5234
UUGAGUUA CUGAUGAGGCCGUUAGGCCGAA IUGUCUGG
14574





5213
CACUUAAC U CAAUUUCU
5235
AGAAAUUG CUGAUGAGGCCGUUAGGCCGAA IUUAAGUG
14575





5215
CUUAACUC A AUUUCUUG
5236
CAAGAAAU CUGAUGAGGCCGUUAGGCCGAA IAGUUAAG
14576





5221
UCAAUUUC U UGGUAUUA
5237
UAAUACCA CUGAUGAGGCCGUUAGGCCGAA IAAAUUGA
14577





5233
UAUUAUUC U GUUUUGCA
5238
UGCAAAAC CUGAUGAGGCCGUUAGGCCGAA IAAUAAUA
14578





5241
UGUUUUGC A CAGUUAGU
5239
ACUAACUG CUGAUGAGGCCGUUAGGCCGAA ICAAAACA
14579





5243
UUUUGCAC A GUUAGUUG
5240
CAACUAAC CUGAUGAGGCCGUUAGGCCGAA IUGCAAAA
14580





5263
AAGAAAGC U GAGAAGAA
5241
UUCUUCUC CUGAUGAGGCCGUUAGGCCGAA ICUUUCUU
14581





5281
GAAAAUGC A GUCCUGAG
5242
CUCAGGAC CUGAUGAGGCCGUUAGGCCGAA ICAUUUUC
14582





5285
AUGCAGUC C UGAGGAGA
5243
UCUCCUCA CUGAUGAGGCCGUUAGGCCGAA IACUGCAU
14583





5286
UGCAGUCC U GAGGAGAG
5244
CUCUCCUC CUGAUGAGGCCGUUAGGCCGAA IGACUGCA
14584





5300
GAGUUUUC U CCAUAUCA
5245
UGAUAUGG CUGAUGAGGCCGUUAGGCCGAA IAAAACUC
14585





5302
GUUUUCUC C AUAUCAAA
5246
UUUGAUAU CUGAUGAGGCCGUUAGGCCGAA IAGAAAAC
14586





5303
UUUUCUCC A UAUCAAAA
5247
UUUUGAUA CUGAUGAGGCCGUUAGGCCGAA IGAGAAAA
14587





5308
UCCAUAUC A AAACGAGG
5248
CCUCGUUU CUGAUGAGGCCGUUAGGCCGAA IAUAUGGA
14588





5319
ACGAGGGC U GAUGGAGG
5249
CCUCCAUC CUGAUGAGGCCGUUAGGCCGAA ICCCUCGU
14589





5337
AAAAGGUC A AUAAGGUC
5250
GACCUUAU CUGAUGAGGCCGUUAGGCCGAA IACCUUUU
14590





5346
AUAAGGUC A AGGGAAGA
5251
UCUUCCCU CUGAUGAGGCCGUUAGGCCGAA IACCUUAU
14591





5356
GGGAAGAC C CCGUCUCU
5252
AGAGACGG CUGAUGAGGCCGUUAGGCCGAA IUCUUCCC
14592





5357
GGAAGACC C CGUCUCUA
5253
UAGAGACG CUGAUGAGGCCGUUAGGCCGAA IGUCUUCC
14593





5358
GAAGACCC C GUCUCUAU
5254
AUAGAGAC CUGAUGAGGCCGUUAGGCCGAA IGGUCUUC
14594





5362
ACCCCGUC U CUAUACCA
5255
UGGUAUAG CUGAUGAGGCCGUUAGGCCGAA IACGGGGU
14595





5364
CCCGUCUC U AUACCAAC
5256
GUUGGUAU CUGAUGAGGCCGUUAGGCCGAA IAGACGGG
14596





5369
CUCUAUAC C AACCAAAC
5257
GUUUGGUU CUGAUGAGGCCGUUAGGCCGAA IUAUAGAG
14597





5370
UCUAUACC A ACCAAACC
5258
GGUUUGGU CUGAUGAGGCCGUUAGGCCGAA IGUAUAGA
14598





5373
AUACCAAC C AAACCAAU
5259
AUUGGUUU CUGAUGAGGCCGUUAGGCCGAA IUUGGUAU
14599





5374
UACCAACC A AACCAAUU
5260
AAUUGGUU CUGAUGAGGCCGUUAGGCCGAA IGUUGGUA
14600





5378
AACCAAAC C AAUUCACC
5261
GGUGAAUU CUGAUGAGGCCGUUAGGCCGAA IUUUGGUU
14601





5379
ACCAAACC A AUUCACCA
5262
UGGUGAAU CUGAUGAGGCCGUUAGGCCGAA IGUUUGGU
14602





5384
ACCAAUUC A CCAACACA
5263
UGUGUUGG CUGAUGAGGCCGUUAGGCCGAA IAAUUGGU
14603





5386
CAAUUCAC C AACACAGU
5264
ACUGUGUU CUGAUGAGGCCGUUAGGCCGAA IUGAAUUG
14604





5387
AAUUCACC A ACACAGUU
5265
AACUGUGU CUGAUGAGGCCGUUAGGCCGAA IGUGAAUU
14605





5390
UCACCAAC A CAGUUGGG
5266
CCCAACUG CUGAUGAGGCCGUUAGGCCGAA IUUGGUGA
14606





5392
ACCAACAC A GUUGGGAC
5267
GUCCCAAC CUGAUGAGGCCGUUAGGCCGAA IUGUUGGU
14607





5401
GUUGGGAC C CAAAACAC
5268
GUGUUUUG CUGAUGAGGCCGUUAGGCCGAA IUCCCAAC
14608





5402
UUGGGACC C AAAACACA
5269
UGUGUUUU CUGAUGAGGCCGUUAGGCCGAA IGUCCCAA
14609





5403
UGGGACCC A AAACACAG
5270
CUGUGUUU CUGAUGAGGCCGUUAGGCCGAA IGGUCCCA
14610





5408
CCCAAAAC A CAGGAAGU
5271
ACUUCCUG CUGAUGAGGCCGUUAGGCCGAA IUUUUGGG
14611





5410
CAAAACAC A GGAAGUCA
5272
UGACUUCC CUGAUGAGGCCGUUAGGCCGAA IUGUUUUG
14612





5418
AGGAAGUC A GUCACGUU
5273
AACGUGAC CUGAUGAGGCCGUUAGGCCGAA IACUUCCU
14613





5422
AGUCAGUC A CGUUUCCU
5274
AGGAAACG CUGAUGAGGCCGUUAGGCCGAA IACUGACU
14614





5429
CACGUUUC C UUUUCAUU
5275
AAUGAAAA CUGAUGAGGCCGUUAGGCCGAA IAAACGUG
14615





5430
ACGUUUCC U UUUCAUUU
5276
AAAUGAAA CUGAUGAGGCCGUUAGGCCGAA IGAAACGU
14616





5435
UCCUUUUC A UUUAAUGG
5277
CCAUUAAA CUGAUGAGGCCGUUAGGCCGAA IAAAAGGA
14617





5450
GGGGAUUC C ACUAUCUC
5278
GAGAUAGU CUGAUGAGGCCGUUAGGCCGAA IAAUCCCC
14618





5451
GGGAUUCC A CUAUCUCA
5279
UGAGAUAG CUGAUGAGGCCGUUAGGCCGAA IGAAUCCC
14619





5453
GAUUCCAC U AUCUCACA
5280
UGUGAGAU CUGAUGAGGCCGUUAGGCCGAA IUGGAAUC
14620





5457
CCACUAUC U CACACUAA
5281
UUAGUGUG CUGAUGAGGCCGUUAGGCCGAA IAUAGUGG
14621





5459
ACUAUCUC A CACUAAUC
5282
GAUUAGUG CUGAUGAGGCCGUUAGGCCGAA IAGAUAGU
14622





5461
UAUCUCAC A CUAAUCUG
5283
CAGACUAG CUGAUGAGGCCGUUAGGCCGAA IUGAGAUA
14623





5463
UCUCACAC U AAUCUGAA
5284
UUCAGAUU CUGAUGAGGCCGUUAGGCCGAA IUGUGAGA
14624





5468
CACUAAUC U GAAAGGAU
5285
AUCCUUUC CUGAUGAGGCCGUUAGGCCGAA IAUUAGUG
14625





5487
GGAAGAGC A UUAGCUGG
5286
CCAGCUAA CUGAUGAGGCCGUUAGGCCGAA ICUCUUCC
14626





5493
GCAUUAGC U GGCGCAUA
5287
UAUGCGCC CUGAUGAGGCCGUUAGGCCGAA ICUAAUGC
14627





5499
GCUGGCGC A UAUUAAGC
5288
GCUUAAUA CUGAUGAGGCCGUUAGGCCGAA ICGCCAGC
14628





5508
UAUUAAGC A CUUUAAGC
5289
GCUUAAAG CUGAUGAGGCCGUUAGGCCGAA ICUUAAUA
14629





5510
UUAAGCAC U UUAAGCUC
5290
GAGCUUAA CUGAUGAGGCCGUUAGGCCGAA IUGCUUAA
14630





5517
CUUUAAGC U CCUUGAGU
5291
ACUCAAGG CUGAUGAGGCCGUUAGGCCGAA ICUUAAAG
14631





5519
UUAAGCUC C UUGAGUAA
5292
UUACUCAA CUGAUGAGGCCGUUAGGCCGAA IAGCUUAA
14632





5520
UAAGCUCC U UGAGUAAA
5293
UUUACUCA CUGAUGAGGCCGUUAGGCCGAA IGAGCUUA
14633





5550
AUUUAUGC A AGGUAUUU
5294
AAAUACCU CUGAUGAGGCCGUUAGGCCGAA ICAUAAAU
14634





5560
GGUAUUUC U CCAGUUGG
5295
CCAACUGG CUGAUGAGGCCGUUAGGCCGAA IAAAUACC
14635





5562
UAUUUCUC C AGUUGGGA
5296
UCCCAACU CUGAUGAGGCCGUUAGGCCGAA IAGAAAUA
14636





5563
AUUUCUCC A GUUGGGAC
5297
GUCCCAAC CUGAUGAGGCCGUUAGGCCGAA IGAGAAAU
14637





5572
GUUGGGAC U CAGGAUAU
5298
AUAUCCUG CUGAUGAGGCCGUUAGGCCGAA IUCCCAAC
14638





5574
UGGGACUC A GGAUAUUA
5299
UAAUAUCC CUGAUGAGGCCGUUAGGCCGAA IAGUCCCA
14639





5593
UAAUGAGC C AUCACUAG
5300
CUAGUGAU CUGAUGAGGCCGUUAGGCCGAA ICUCAUUA
14640





5594
AAUGAGCC A UCACUAGA
5301
UCUAGUGA CUGAUGAGGCCGUUAGGCCGAA IGCUCAUU
14641





5597
GAGCCAUC A CUAGAAGA
5302
UCUUCUAG CUGAUGAGGCCGUUAGGCCGAA IAUGGCUC
14642





5599
GCCAUCAC U AGAAGAAA
5303
UUUCUUCU CUGAUGAGGCCGUUAGGCCGAA IUGAUGGC
14643





5611
AGAAAAGC C CAUUUUCA
5304
UGAAAAUG CUGAUGAGGCCGUUAGGCCGAA ICUUUUCU
14644





5612
GAAAAGCC C AUUUUCAA
5305
UUGAAAAU CUGAUGAGGCCGUUAGGCCGAA IGCUUUUC
14645





5613
AAAAGCCC A UUUUCAAC
5306
GUUGAAAA CUGAUGAGGCCGUUAGGCCGAA IGGCUUUU
14646





5619
CCAUUUUC A ACUGCUUU
5307
AAAGCAGU CUGAUGAGGCCGUUAGGCCGAA IAAAAUGG
14647





5622
UUUUCAAC U GCUUUGAA
5308
UUCAAAGC CUGAUGAGGCCGUUAGGCCGAA IUUGAAAA
14648





5625
UCAACUGC U UUGAAACU
5309
AGUUUCAA CUGAUGAGGCCGUUAGGCCGAA ICAGUUGA
14649





5633
UUUGAAAC U UGCCUGGG
5310
CCCAGGCA CUGAUGAGGCCGUUAGGCCGAA IUUUCAAA
14650





5637
AAACUUGC C UGGGGUCU
5311
AGACCCCA CUGAUGAGGCCGUUAGGCCGAA ICAAGUUU
14651





5638
AACUUGCC U GGGGUCUG
5312
CAGACCCC CUGAUGAGGCCGUUAGGCCGAA IGCAAGUU
14652





5645
CUGGGGUC U GAGCAUGA
5313
UCAUGCUC CUGAUGAGGCCGUUAGGCCGAA IACCCCAG
14653





5650
GUCUGAGC A UGAUGGGA
5314
UCCCAUCA CUGAUGAGGCCGUUAGGCCGAA ICUCAGAC
14654





5669
AGGGAGAC A GGGUAGGA
5315
UCCUACCC CUGAUGAGGCCGUUAGGCCGAA IUCUCCCU
14655





5686
AAGGGCGC C UACUCUUC
5316
GAAGAGUA CUGAUGAGGCCGUUAGGCCGAA ICGCCCUU
14656





5687
AGGGCGCC U ACUCUUCA
5317
UGAAGAGU CUGAUGAGGCCGUUAGGCCGAA IGCGCCCU
14657





5690
GCGCCUAC U CUUCAGGG
5318
CCCUGAAG CUGAUGAGGCCGUUAGGCCGAA IUAGGCGC
14658





5692
GCCUACUC U UCAGGGUC
5319
GACCCUGA CUGAUGAGGCCGUUAGGCCGAA IAGUAGGC
14659





5695
UACUCUUC A GGGUCUAA
5320
UUAGACCC CUGAUGAGGCCGUUAGGCCGAA IAAGAGUA
14660





5701
UCAGGGUC U AAAGAUCA
5321
UGAUCUUU CUGAUGAGGCCGUUAGGCCGAA IACCCUGA
14661





5709
UAAAGAUC A AGUGGGCC
5322
GGCCCACU CUGAUGAGGCCGUUAGGCCGAA IAUCUUUA
14662





5717
AAGUGGGC C UUGGAUCG
5323
CGAUCCAA CUGAUGAGGCCGUUAGGCCGAA ICCCACUU
14663





5718
AGUGGGCC U UGGAUCGC
5324
GCGAUCCA CUGAUGAGGCCGUUAGGCCGAA IGCCCACU
14664





5727
UGGAUCGC U AAGCUGGC
5325
GCCAGCUU CUGAUGAGGCCGUUAGGCCGAA ICGAUCCA
14665





5732
CGCUAAGC U GGCUCUGU
5326
ACAGAGCC CUGAUGAGGCCGUUAGGCCGAA ICUUAGCG
14666





5736
AAGCUGGC U CUGUUUGA
5327
UCAAACAG CUGAUGAGGCCGUUAGGCCGAA ICCAGCUU
14667





5738
GCUGGCUC U GUUUGAUG
5328
CAUCAAAC CUGAUGAGGCCGUUAGGCCGAA IAGCCAGC
14668





5748
UUUGAUGC U AUUUAUGC
5329
GCAUAAAU CUGAUGAGGCCGUUAGGCCGAA ICAUCAAA
14669





5757
AUUUAUGC A AGUUAGGG
5330
CCCUAACU CUGAUGAGGCCGUUAGGCCGAA ICAUAAAU
14670





5768
UUAGGGUC U AUGUAUUU
5331
AAAUACAU CUGAUGAGGCCGUUAGGCCGAA IACCCUAA
14671





5786
GGAUGCGC C UACUCUUC
5332
GAAGAGUA CUGAUGAGGCCGUUAGGCCGAA ICGCAUCC
14672





5787
GAUGCGCC U ACUCUUCA
5333
UGAAGAGU CUGAUGAGGCCGUUAGGCCGAA IGCGCAUC
14673





5790
GCGCCUAC U CUUCAGGG
5318
CCCUGAAG CUGAUGAGGCCGUUAGGCCGAA IUAGGCGC
14658





5792
GCCUACUC U UCAGGGUC
5319
GACCCUGA CUGAUGAGGCCGUUAGGCCGAA IAGUAGGC
14659





5795
UACUCUUC A GGGUCUAA
5320
UUAGACCC CUGAUGAGGCCGUUAGGCCGAA IAAGAGUA
14660





5801
UCAGGGUC U AAAGAUCA
5321
UGAUCUUU CUGAUGAGGCCGUUAGGCCGAA IACCCUGA
14661





5809
UAAAGAUC A AGUGGGCC
5322
GGCCCACU CUGAUGAGGCCGUUAGGCCGAA IAUCUUUA
14662





5817
AAGUGGGC C UUGGAUCG
5323
CGAUCCAA CUGAUGAGGCCCUUAGGCCGAA ICCCACUU
14663





5818
AGUGGGCC U UGGAUCGC
5324
GCGAUCCA CUGAUGAGGCCGUUAGGCCGAA IGCCCACU
14664





5827
UGGAUCGC U AAGCUGGC
5325
GCCAGCUU CUGAUGAGGCCGUUAGGCCGAA ICGAUCCA
14665





5832
CGCUAAGC U GGCUCUGU
5326
ACAGAGCC CUGAUGAGGCCGUUAGGCCGAA ICUUAGCG
14666





5836
AAGCUGGC U CUGUUUGA
5327
UCAAACAG CUGAUGAGGCCGUUACGCCGAA ICCAGCUU
14667





5838
GCUGGCUC U GUUUGAUG
5328
CAUCAAAC CUGAUGAGGCCGUUAGGCCGAA IAGCCAGC
14668





5848
UUUGAUGC U AUUUAUGC
5329
GCAUAAAU CUGAUGAGGCCCUUAGGCCGAA ICAUCAAA
14669





5857
AUUUAUGC A AGUUAGGG
5330
CCCUAACU CUGAUGAGGCCGUUAGGCCGAA ICAUAAAU
14670





5868
UUAGGGUC U AUGUAUUU
5331
AAAUACAU CUGAUGAGGCCGUUAGGCCGAA IACCCUAA
14671





5885
AGGAUGUC U GCACCUUC
5334
GAAGGUGC CUGAUGAGGCCGUUAGGCCGAA IACAUCCU
14674





5888
AUGUCUGC A CCUUCUGC
5335
GCAGAAGG CUGAUGAGGCCCUUAGGCCGAA ICAGACAU
14675





5890
GUCUGCAC C UUCUGCAG
5336
CUGCAGAA CUGAUGAGGCCGUUAGGCCGAA IUGCAGAC
14676





5891
UCUGCACC U UCUGCAGC
5337
GCUGCAGA CUGAUGAGGCCGUUAGGCCGAA IGUGCAGA
14677





5894
GCACCUUC U GCAGCCAG
5338
CUGGCUGC CUGAUGAGGCCGUUAGGCCGAA IAAGGUGC
14678





5897
CCUUCUGC A GCCAGUCA
5339
UGACUGGC CUGAUGAGGCCGUUAGGCCGAA ICAGAAGG
14679





5900
UCUGCAGC C AGUCAGAA
5340
UUCUGACU CUGAUGAGGCCGUUAGGCCGAA ICUGCAGA
14680





5901
CUGCAGCC A GUCAGAAG
5341
CUUCUGAC CUGAUGAGGCCGUUAGGCCGAA IGCUGCAG
14681





5905
AGCCAGUC A GAAGCUGG
5342
CCAGCUUC CUGAUGAGGCCGUUAGGCCGAA IACUGGCU
14682





5911
UCAGAAGC U GGAGAGGC
5343
GCCUCUCC CUGAUGAGGCCGUUAGGCCGAA ICUUCUGA
14683





5920
GGAGAGGC A ACAGUGGA
5344
UCCACUGU CUGAUGAGGCCGUUAGGCCGAA ICCUCUCC
14684





5923
GAGGCAAC A GUGGAUUG
5345
CAAUCCAC CUGAUGAGGCCGUUAGGCCGAA IUUGCCUC
14685





5933
UGGAUUGC U GCUUCUUG
5346
CAAGAAGC CUGAUGAGGCCGUUAGGCCGAA ICAAUCCA
14686





5936
AUUGCUGC U UCUUGGGG
5347
CCCCAAGA CUGAUGAGGCCGUUAGGCCGAA ICAGCAAU
14687





5939
GCUGCUUC U UGGGGAGA
5348
UCUCCCCA CUGAUGAGGCCGUUAGGCCGAA IAAGCAGC
14688





5957
GAGUAUGC U UCCUUUUA
5349
UAAAAGGA CUGAUGAGGCCGUUAGGCCGAA ICAUACUC
14689





5960
UAUGCUUC C UUUUAUCC
5350
GGAUAAAA CUGAUGAGGCCGUUAGGCCGAA IAAGCAUA
14690





5961
AUGCUUCC U UUUAUCCA
5351
UGGAUAAA CUGAUGAGGCCGUUAGGCCGAA IGAAGCAU
14691





5968
CUUUUAUC C AUGUAAUU
5352
AAUUACAU CUGAUGAGGCCGUUAGGCCGAA IAUAAAAG
14692





5969
UUUUAUCC A UGUAAUUU
5353
AAAUUACA CUGAUGAGGCCGUUAGGCCGAA IGAUAAAA
14693





5981
AAUUUAAC U GUAGAACC
5354
GGUUCUAC CUGAUGAGGCCGUUAGGCCGAA IUUAAAUU
14694





5989
UGUAGAAC C UGAGCUCU
5355
AGAGCUCA CUGAUGAGGCCGUUACGCCGAA IUUCUACA
14695





5990
GUAGAACC U GAGCUCUA
5356
UAGAGCUC CUGAUGAGGCCGUUAGGCCGAA IGUUCUAC
14696





5995
ACCUGAGC U CUAAGUAA
5357
UUACUUAG CUGAUGAGGCCGUUAGGCCGAA ICUCAGGU
14697





5997
CUGAGCUC U AAGUAACC
5358
GGUUACUU CUGAUGAGGCCGUUAGGCCGAA IACCUCAG
14698





6005
UAAGUAAC C GAAGAAUG
5359
CAUUCUUC CUGAUGAGGCCGUUAGGCCGAA IUUACUUA
14699





6019
AUGUAUGC C UCUGUUCU
5360
AGAACAGA CUGAUGAGGCCGUUAGGCCGAA ICAUACAU
14700





6020
UGUAUGCC U CUGUUCUU
5361
AAGAACAG CUGAUGAGGCCGUUAGGCCGAA IGCAUACA
14701





6022
UAUGCCUC U GUUCUUAU
5362
AUAAGAAC CUGAUGAGGCCGUUAGGCCGAA IAGGCAUA
14702





6027
CUCUGUUC U UAUGUGCC
5363
GGCACAUA CUGAUGAGGCCGUUAGGCCGAA IAACAGAG
14703





6035
UUAUGUGC C ACAUCCUU
5364
AAGGAUGU CUGAUGAGGCCGUUAGGCCGAA ICACAUAA
14704





6036
UAUGUGCC A CAUCCUUG
5365
CAAGGAUG CUGAUGAGGCCGUUAGGCCGAA IGCACAUA
14705





6038
UGUGCCAC A UCCUUGUU
5366
AACAAGGA CUGAUGAGGCCGUUAGGCCGAA IUGGCACA
14706





6041
GCCACAUC C UUGUUUAA
5367
UUAAACAA CUGAUGAGGCCGUUAGGCCGAA IAUGUGGC
14707





6042
CCACAUCC U UGUUUAAA
5368
UUUAAACA CUGAUGAGGCCGUUAGGCCGAA ICAUGUGG
14708





6054
UUAAAGGC U CUCUGUAU
5369
AUACAGAG CUGAUGAGGCCGUUAGGCCGAA ICCUUUAA
14709





6056
AAAGGCUC U CUGUAUGA
5370
UCAUACAG CUGAUGAGGCCGUUAGGCCGAA IAGCCUUU
14710





6058
AGGCUCUC U GUAUGAAG
5371
CUUCAUAC CUGAUGAGGCCGUUAGGCCGAA IAGAGCCU
14711





6076
GAUGGGAC C GUCAUCAG
5372
CUGAUGAC CUGAUGAGGCCGUUAGGCCGAA IUCCCAUC
14712





6080
GGACCGUC A UCAGCACA
5373
UGUGCUGA CUGAUGAGGCCGUUAGGCCGAA IACGGUCC
14713





6083
CCGUCAUC A GCACAUUC
5374
GAAUGUGC CUGAUGAGGCCGUUAGGCCGAA IAUGACGG
14714





6086
UCAUCAGC A CAUUCCCU
5375
AGGGAAUG CUGAUGAGGCCGUUAGGCCGAA ICUGAUGA
14715





6088
AUCAGCAC A UUCCCUAG
5376
CUAGGGAA CUGAUGAGGCCGUUAGGCCGAA IUGCUGAU
14716





6092
GCACAUUC C CUAGUGAG
5377
CUCACUAG CUGAUGAGGCCGUUAGGCCGAA IAAUGUGC
14717





6093
CACAUUCC C UAGUGAGC
5378
GCUCACUA CUGAUGAGGCCGUUAGGCCGAA IGAAUGUG
14718





6094
ACAUUCCC U AGUGAGCC
5379
GGCUCACU CUGAUGAGGCCGUUAGGCCGAA IGGAAUGU
14719





6102
UAGUGAGC C UACUGGCU
5380
AGCCAGUA CUGAUGAGGCCGUUAGGCCGAA ICUCACUA
14720





6103
AGUGAGCC U ACUGGCUC
5381
GAGCCAGU CUGAUGAGGCCGUUAGGCCGAA IGCUCACU
14721





6106
GAGCCUAC U GGCUCCUG
5382
CAGGAGCC CUGAUGAGGCCGUUAGGCCGAA IUAGGCUC
14722





6110
CUACUGGC U CCUGGCAG
5383
CUGCCAGG CUGAUGAGGCCGUUAGGCCGAA ICCAGUAG
14723





6112
ACUGGCUC C UGGCAGCG
5384
CGCUGCCA CUGAUGAGGCCGUUAGGCCGAA IAGCCAGU
14724





6113
CUGGCUCC U GGCAGCGG
5385
CCGCUGCC CUGAUGAGGCCGUUAGGCCGAA IGAGCCAG
14725





6117
CUCCUGGC A GCGGCUUU
5386
AAAGCCGC CUGAUGAGGCCGUUAGGCCGAA ICCAGGAG
14726





6123
GCAGCGGC U UUUGUGGA
5387
UCCACAAA CUGAUGAGGCCGUUAGGCCGAA ICCGCUGC
14727





6136
UGGAAGAC U CACUAGCC
5388
GGCUAGUG CUGAUGAGGCCGUUAGGCCGAA IUCUUCCA
14728





6138
GAAGACUC A CUAGCCAG
5389
CUGOCUAG CUGAUGAGGCCGUUAGGCCGAA IAGUCUUC
14729





6140
AGACUCAC U AGCCAGAA
5390
UUCUGGCU CUGAUGAGGCCGUUAGGCCGAA IUGAGUCU
14730





6144
UCACUAGC C AGAAGAGA
5391
UCUCUUCU CUGAUGAGGCCGUUAGGCCGAA ICUAGUGA
14731





6145
CACUAGCC A GAAGAGAG
5392
CUCUCUUC CUGAUGAGGCCGUUAGGCCGAA IGCUAGUG
14732





6163
AGUGGGAC A GUCCUCUC
5393
GAGAGGAC CUGAUGAGGCCGUUAGGCCGAA IUCCCACU
14733





6167
GGACAGUC C UCUCCACC
5394
GGUGGAGA CUGAUGAGGCCGUUAGGCCGAA IACUGUCC
14734





6168
GACAGUCC U CUCCACCA
5395
UGGUGGAG CUGAUGAGGCCGUUAGGCCGAA IGACUGUC
14735





6170
CAGUCCUC U CCACCAAG
5396
CUUGGUGG CUGAUGAGGCCGUUAGGCCGAA IAGGACUG
14736





6172
GUCCUCUC C ACCAAGAU
5397
AUCUUGGU CUGAUGAGGCCGUUAGGCCGAA IAGAGGAC
14737





6173
UCCUCUCC A CCAAGAUC
5398
GAUCUUGG CUGAUGAGGCCGUUAGGCCGAA IGAGAGGA
14738





6175
CUCUCCAC C AAGAUCUA
5399
UAGAUCUU CUGAUGAGGCCGUUAGGCCGAA IUGGAGAG
14739





6176
UCUCCACC A AGAUCUAA
5400
UUAGAUCU CUGAUGAGGCCGUUAGGCCGAA IGUGGAGA
14740





6182
CCAAGAUC U AAAUCCAA
5401
UUGGAUUU CUGAUGAGGCCGUUAGGCCGAA IAUCUUGG
14741





6188
UCUAAAUC C AAACAAAA
5402
UUUUGUUU CUGAUGAGGCCGUUAGGCCGAA IAUUUAGA
14742





6189
CUAAAUCC A AACAAAAG
5403
CUUUUGUU CUGAUGAGGCCGUUAGGCCGAA IGAUUUAG
14743





6193
AUCCAAAC A AAAGCAGG
5404
CCUGCUUU CUGAUGAGGCCGUUAGGCCGAA IUUUGGAU
14744





6199
ACAAAAGC A GGCUAGAG
5405
CUCUAGCC CUGAUGAGGCCGUUAGGCCGAA ICUUUUGU
14745





6203
AAGCAGGC U AGAGCCAG
5406
CUGGCUCU CUGAUGAGGCCGUUAGGCCGAA ICCUGCUU
14746





6209
GCUAGAGC C AGAAGAGA
5407
UCUCUUCU CUGAUGAGGCCGUUAGGCCGAA ICUCUAGC
14747





6210
CUAGAGCC A GAAGAGAG
5408
CUCUCUUC CUGAUGAGGCCGUUAGGCCGAA IGCUCUAG
14748





6222
GAGAGGAC A AAUCUUUG
5409
CAAAGAUU CUGAUGAGGCCGUUAGGCCGAA IUCCUCUC
14749





6227
GACAAAUC U UUGUUGUU
5410
AACAACAA CUGAUGAGGCCGUUAGGCCGAA IAUUGGUC
14750





6237
UGUUGUUC C UCUUCUUU
5411
AAAGAAGA CUGAUGAGGCCGUUAGGCCGAA IAACAACA
14751





6238
GUUGUUCC U CUUCUUUA
5412
UAAAGAAG CUGAUGAGGCCGUUAGGCCGAA IGAACAAC
14752





6240
UGUUCCUC U UCUUUACA
5413
UGUAAAGA CUGAUGAGGCCGUUAGGCCGAA IAGGAACA
14753





6243
UCCUCUUC U UUACACAU
5414
AUGUGUAA CUGAUGAGGCCGUUAGGCCGAA IAAGAGGA
14754





6248
UUCUUUAC A CAUACGCA
5415
UGCGUAUG CUGAUGAGGCCGUUAGGCCGAA IUAAAGAA
14755





6250
CUUUACAC A UACGCAAA
5416
UUUGCGUA CUGAUGAGGCCGUUAGGCCGAA IUGUAAAG
14756





6256
ACAUACGC A AACCACCU
5417
AGGUGGUU CUGAUGAGGCCGUUAGGCCGAA ICGUAUGU
14757





6260
ACGCAAAC C ACCUGUGA
5418
UCACAGGU CUGAUGAGGCCGUUAGGCCGAA IUUUGCGU
14758





6261
CGCAAACC A CCUGUGAC
5419
GUCACAGG CUGAUGAGGCCGUUAGGCCGAA IGUUUGCG
14759





6263
CAAACCAC C UGUGACAG
5420
CUGUCACA CUGAUGAGGCCGUUAGGCCGAA IUGGUUUG
14760





6264
AAACCACC U GUGACAGC
5421
GCUGUCAC CUGAUGAGGCCGUUAGGCCGAA IGUGGUUU
14761





6270
CCUGUGAC A GCUGGCAA
5422
UUGCCAGC CUGAUGAGGCCGUUAGGCCGAA IUCACAGG
14762





6273
GUGACAGC U GGCAAUUU
5423
AAAUUGCC CUGAUGAGGCCGUUAGGCCGAA ICUGUCAC
14763





6277
CAGCUGGC A AUUUUAUA
5424
UAUAAAAU CUGAUGAGGCCGUUAGGCCGAA ICCAGCUG
14764





6290
UAUAAAUC A GGUAACUG
5425
CAGUUACC CUGAUGAGGCCGUUAGGCCGAA IAUUUAUA
14765





6297
CAGGUAAC U GGAAGGAG
5426
CUCCUUCC CUGAUGAGGCCGUUAGGCCGAA IUUACCUG
14766





6313
GGUUAAAC U CAGAAAAA
5427
UUUUUCUG CUGAUGAGGCCGUUAGGCCGAA IUUUAACC
14767





6315
UUAAACUC A GAAAAAAG
5428
CUUUUUUC CUGAUGAGGCCGUUAGGCCGAA IAGUUUAA
14768





6329
AAGAAGAC C UCAGUCAA
5429
UUGACUGA CUGAUGAGGCCGUUAGGCCGAA IUCUUCUU
14769





6330
AGAAGACC U CAGUCAAA
5430
AUUGACUG CUGAUGAGGCCGUUAGGCCGAA IGUCUUCU
14770





6332
AAGACCUC A GUCAAUUC
5431
GAAUUGAC CUGAUGAGGCCGUUAGGCCGAA IAGGUCUU
14771





6336
CCUCAGUC A AUUCUCUA
5432
UAGAGAAU CUGAUGAGGCCGUUAGGCCGAA IACUGAGG
14772





6341
GUCAAUUC U CUACUUUU
5433
AAAAGUAG CUGAUGAGGCCGUUAGGCCGAA IAAUUGAC
14773





6343
CAAUUCUC U ACUUUUUU
5434
AAAAAAGU CUGAUGAGGCCGUUAGGCCGAA IAGAAUUG
14774





6346
UUCUCUAC U UUUUUUUU
5435
AAAAAAAA CUGAUGAGGCCGUUAGGCCGAA IUAGAGAA
14775





6363
UUUUUUUC C AAAUCAGA
5436
UCUGAUUU CUGAUGAGGCCGUUAGGCCGAA IAAAAAAA
14776





6364
UUUUUUCC A AAUCAGAU
5437
AUCUGAUU CUGAUGAGGCCGUUAGGCCGAA IGAAAAAA
14777





6369
UCCAAAUC A GAUAAUAG
5438
CUAUUAUC CUGAUGAGGCCGUUAGGCCGAA IAUUUGGA
14778





6379
AUAAUAGC C CAGCAAAU
5439
AUUUGCUG CUGAUGAGGCCGUUAGGCCGAA ICUAUUAU
14779





6380
UAAUAGCC C AGCAAAUA
5440
UAUUUGCU CUGAUGAGGCCGUUAGGCCGAA IGCUAUUA
14780





6381
AAUAGCCC A GCAAAUAG
5441
CUAUUUGC CUGAUGAGGCCGUUAGGCCGAA IGGCUAUU
14781





6384
AGCCCAGC A AAUAGUGA
5442
UCACUAUU CUGAUGAGGCCGUUAGGCCGAA ICUGGGCU
14782





6397
GUGAUAAC A AAUAAAAC
5443
GUUUUAUU CUGAUGAGGCCGUUAGGCCGAA IUUAUCAC
14783





6406
AAUAAAAC C UUAGCUGU
5444
ACAGCUAA CUGAUGAGGCCGUUAGGCCGAA IUUUUAUU
14784





6407
AUAAAACC U UAGCUGUU
5445
AACAGCUA CUGAUGAGGCCGUUAGGCCGAA IGUUUUAU
14785





6412
ACCUUAGC U GUUCAUGU
5446
ACAUGAAC CUGAUGAGGCCGUUAGGCCGAA ICUAAGGU
14786





6417
AGCUGUUC A UGUCUUGA
5447
UCAAGACA CUGAUGAGGCCGUUAGGCCGAA IAACAGCU
14787





6422
UUCAUGUC U UGAUUUCA
5448
UGAAAUCA CUGAUGAGGCCGUUAGGCCGAA IACAUGAA
14788





6430
UUGAUUUC A AUAAUUAA
5449
UUAAUUAU CUGAUGAGGCCGUUAGGCCGAA IAAAUCAA
14789





6442
AUUAAUUC U UAAUCAUU
5450
AAUGAUUA CUGAUGAGGCCGUUAGGCCGAA IAAUUAAU
14790





6448
UCUUAAUC A UUAAGAGA
5451
UCUCUUAA CUGAUGAGGCCGUUAGGCCGAA IAUUAAGA
14791





6458
UAAGAGAC C AUAAUAAA
5452
UUUAUUAU CUGAUGAGGCCGUUAGGCCGAA IUCUCUUA
14792





6459
AAGAGACC A UAAUAAAU
5453
AUUUAUUA CUGAUGAGGCCGUUAGGCCGAA IGUCUCUU
14793





6470
AUAAAUAC U CCUUUUCA
5454
UGAAAAGG CUGAUGAGGCCGUUAGGCCGAA IUAUUUAU
14794





6472
AAAUACUC C UUUUCAAG
5455
CUUGAAAA CUGAUGAGGCCGUUAGGCCGAA IAGUAUUU
14795





6473
AAUACUCC U UUUCAAGA
5456
UCUUGAAA CUGAUGAGGCCGUUAGGCCGAA IGAGUAUU
14796





6478
UCCUUUUC A AGAGAAAA
5457
UUUUCUCU CUGAUGAGGCCGUUAGGCCGAA IAAAAGGA
14797





6489
AGAAAAGC A AAACCAUU
5458
AAUGGUUU CUGAUGAGGCCGUUAGGCCGAA ICUUUUCU
14798





6494
AGCAAAAC C AUUAGAAU
5459
AUUCUAAU CUGAUGAGGCCGUUAGGCCGAA IUUUUGCU
14799





6495
GCAAAACC A UUAGAAUU
5460
AAUUCUAA CUGAUGAGGCCGUUAGGCCGAA IGUUUUGC
14800





6509
AUUGUUAC U CAGCUCCU
5461
AGGAGCUG CUGAUGAGGCCGUUAGGCCGAA IUAACAAU
14801





6511
UGUUACUC A GCUCCUUC
5462
GAAGGAGC CUGAUGAGGCCGUUAGGCCGAA IAGUAACA
14802





6514
UACUCAGC U CCUUCAAA
5463
UUUGAAGG CUGAUGAGGCCGUUAGGCCGAA ICUGAGUA
14803





6516
CUCAGCUC C UUCAAACU
5464
AGUUUGAA CUGAUGAGCCCGUUAGGCCGAA IAGCUGAG
14804





6517
UCAGCUCC U UCAAACUC
5465
GAGUUUGA CUGAUGAGGCCGUUAGGCCGAA IGAGOUGA
14805





6520
GCUCCUUC A AACUCAGG
5466
CCUGAGUU CUGAUGAGGCCGUUAGGCCGAA IAAGGAGC
14806





6524
CUUCAAAC U CAGGUUUG
5467
CAAACCUG CUGAUGAGGCCGUUAGGCCGAA IUUUGAAG
14807





6526
UCAAACUC A GGUUUGUA
5468
UACAAACC CUGAUGAGGCCGUUAGGCCGAA IAGUUUGA
14808





6537
UUUGUAGC A UACAUGAG
5469
CUCAUGUA CUGAUGAGGCCGUUAGGCCGAA ICUACAAA
14809





6541
UAGCAUAC A UGAGUCCA
5470
UGGACUCA CUGAUGAGGCCGUUAGGCCGAA IUAUGCUA
14810





6548
CAUGAGUC C AUCCAUCA
5471
UGAUGGAU CUGAUGAGGCCGUUAGGCCGAA IACUCAUG
14811





6549
AUGAGUCC A UCCAUCAG
5472
CUGAUGGA CUGAUGAGGCCGUUAGGCCGAA IGACUCAU
14812





6552
AGUCCAUC C AUCAGUCA
5473
UGACUGAU CUGAUGAGGCCGUUAGGCCGAA IAUGGACU
14813





6553
GUCCAUCC A UCAGUCAA
5474
UUGACUGA CUGAUGAGGCCGUUAGGCCGAA IGAUGGAC
14814





6556
CAUCCAUC A GUCAAAGA
5475
UCUUUGAC CUGAUGAGGCCGUUAGGCCGAA IAUGGAUG
14815





6560
CAUCAGUC A AAGAAUGG
5476
CCAUUCUU CUGAUGAGGCCGUUAGGCCGAA IACUGAUG
14816





6572
AAUGGUUC C AUCUGGAG
5477
CUCCAGAU CUGAUGAGGCCGUUAGGCCGAA IAACCAUU
14817





6573
AUGGUUCC A UCUGGAGU
5478
ACUCCAGA CUGAUGAGGCCGUUAGGCCGAA IGAACCAU
14818





6576
GUUCCAUC U GGAGUCUU
5479
AAGACUCC CUGAUGAGGCCGUUAGGCCGAA IAUGGAAC
14819





6583
CUGGAGUC U UAAUGUAG
5480
CUACAUUA CUGAUGAGGCCGUUAGGCCGAA IACUCCAG
14820





6608
AUGGAGAC U UGUAAUAA
5481
UUAUUACA CUGAUGAGGCCGUUAGGCCGAA IUCUCCAU
14821





6622
UAAUGAGC U AGUUACAA
5482
UUGUAACU CUGAUGAGGCCGUUAGGCCGAA ICUCAUUA
14822





6629
CUAGUUAC A AAGUGCUU
5483
AAGCACUU CUGAUGAGGCCGUUAGGCCGAA IUAACUAG
14823





6636
CAAAGUGC U UGUUCAUU
5484
AAUGAACA CUGAUGAGGCCGUUAGGCCGAA ICACUUUG
14824





6642
GCUUGUUC A UUAAAAUA
5485
UAUUUUAA CUGAUGAGGCCGUUAGGCCGAA IAACAAGC
14825





6653
AAAAUAGC A CUGAAAAU
5486
AUUUUCAG CUGAUGAGGCCGUUAGGCCGAA ICUAUUUU
14826





6655
AAUAGCAC U GAAAAUUG
5487
CAAUUUUC CUGAUGAGGCCGUUAGGCCGAA IUGCUAUU
14827





6668
AUUGAAAC A UGAAUUAA
5488
UUAAUUCA CUGAUGAGGCCGUUAGGCCGAA IUUUCAAU
14828





6678
GAAUUAAC U GAUAAUAU
5489
AUAUUAUC CUGAUGAGGCCGUUAGGCCGAA IUUAAUUC
14829





6689
UAAUAUUC C AAUCACAU
5490
AAAUGAUU CUGAUGAGGCCGUUAGGCCGAA IAAUAUUA
14830





6690
AAUAUUCC A AUCAUUUG
5491
CAAAUGAU CUGAUGAGGCCGUUAGGCCGAA IGAAUAUU
14831





6694
UUCCAAUC A UUUGCCAU
5492
AUGGCAAA CUGAUGAGGCCGUUAGGCCGAA IAUUGGAA
14832





6700
UCAUUUGC C AUUUAUGA
5493
UCAUAAAU CUGAUGAGGCCGUUAGGCCGAA ICAAAUGA
14833





6701
CAUUUGCC A UUUAUGAC
5494
GUCAUAAA CUGAUGAGGCCGUUAGGCCGAA IGCAAAUG
14834





6710
UUUAUGAC A AAAAUGGU
5495
ACCAUUUU CUGAUGAGGCCGUUAGGCCGAA IUCAUAAA
14835





6723
UGGUUGGC A CUAACAAA
5496
UUUGUUAG CUGAUGAGGCCGUUAGGCCGAA ICCAACCA
14836





6725
GUUGGCAC U AACAAAGA
5497
UCUUUGUU CUGAUGAGGCCGUUAGGCCGAA IUGCCAAC
14837





6729
GCACUAAC A AAGAACGA
5498
UCGUUCUU CUGAUGAGGCCGUUAGGCCGAA IUUAGUGC
14838





6740
GAACGAGC A CUUCCUUU
5499
AAAGGAAG CUGAUGAGGCCGUUAGGCCGAA ICUCGUUC
14839





6742
ACGAGCAC U UCCUUUCA
5500
UGAAAGGA CUGAUGAGGCCGUUAGGCCGAA IUGCUCGU
14840





6745
AGCACUUC C UUUCAGAG
5501
CUCUGAAA CUGAUGAGGCCGUUAGGCCGAA IAAGUGCU
14841





6746
GCACUUCC U UUCAGAGU
5502
ACUCUGAA CUGAUGAGGCCGUUAGGCCGAA IGAAGUGC
14842





6750
UUCCUUUC A GAGUUUCU
5503
AGAAACUC CUGAUGAGGCCGUUAGGCCGAA IAAAGGAA
14843





6758
AGAGUUUC U GAGAUAAU
5504
AUUAUCUC CUGAUGAGGCCGUUAGGCCGAA IAAACUCU
14844





6778
CGUGGAAC A GUCUGGGU
5505
ACCCAGAC CUGAUGAGGCCGUUAGGCCGAA IUUCCACG
14845





6782
GAACAGUC U GGGUGGAA
5506
UUCCACCC CUGAUGAGGCCGUUAGGCCGAA IACUGUUC
14846





6797
AAUGGGGC U GAAACCAU
5507
AUGGUUUC CUGAUGAGGCCGUUAGGCCGAA ICCCCAUU
14847





6803
GCUGAAAC C AUGUGCAA
5508
UUGCACAU CUGAUGAGGCCGUUAGGCCGAA IUUUCAGC
14848





6804
CUGAAACC A UGUGCAAG
5509
CUUGCACA CUGAUGAGGCCGUUAGGCCGAA IGUUUCAG
14849





6810
CCAUGUGC A AGUCUGUG
5510
CACAGACU CUGAUGAGGCCGUUAGGCCGAA ICACAUGG
14850





6815
UGCAAGUC U GUGUCUUG
5511
CAAGACAC CUGAUGAGGCCGUUAGGCCGAA IACUUGCA
14851





6821
UCUGUGUC U UGUCAGUC
5512
GACUGACA CUGAUGAGGCCGUUAGGCCGAA IACACAGA
14852





6826
GUCUUGUC A GUCCAAGA
5513
UCUUGGAC CUGAUGAGGCCGUUAGGCCGAA IACAAGAC
14853





6830
UGUCAGUC C AAGAAGUG
5514
CACUUCUU CUGAUGAGGCCGUUAGGCCGAA IACUGACA
14854





6831
GUCAGUCC A AGAAGUGA
5515
UCACUUCU CUGAUGAGGCCGUUAGGCCGAA IGACUGAC
14855





6841
GAAGUGAC A CCGAGAUG
5516
CAUCUCGG CUGAUGAGGCCGUUAGGCCGAA IUCACUUC
14856





6843
AGUGACAC C GAGAUGUU
5517
AACAUCUC CUGAUGAGGCCGUUAGGCCGAA IUGUCACU
14857





6864
UUAGGGAC C CGUGCCUU
5518
AAGGCACG CUGAUGAGGCCGUUAGGCCGAA IUCCCUAA
14858





6865
UAGGGACC C GUGCCUUG
5519
CAAGGCAC CUGAUGAGGCCGUUAGGCCGAA IGUCCCUA
14859





6870
ACCCGUGC C UUGUUUCC
5520
GGAAACAA CUGAUGAGGCCGUUAGGCCGAA ICACGGGU
14860





6871
CCCGUGCC U UGUUUCCU
5521
AGGAAACA CUGAUGAGGCCGUUAGGCCGAA IGCACGGG
14861





6878
CUUGUUUC C UAGCCCAC
5522
GUGGGCUA CUGAUGAGGCCGUUAGGCCGAA IAAACAAG
14862





6879
UUGUUUCC U AGCCCACA
5523
UGUGGGCU CUGAUGAGGCCGUUAGGCCGAA IGAAACAA
14863





6883
UUCCUAGC C CACAAGAA
5524
UUCUUGUG CUGAUGAGGCCGUUAGGCCGAA ICUAGGAA
14864





6884
UCCUAGCC C ACAAGAAU
5525
AUUCUUGU CUGAUGAGGCCGUUAGGCCGAA IGCUAGGA
14865





6885
CCUAGCCC A CAAGAAUG
5526
CAUUCUUG CUGAUGAGGCCGUUAGGCCGAA IGGCUAGG
14866





6887
UAGCCCAC A AGAAUGCA
5527
UGCAUUCU CUGAUGAGGCCGUUAGGCCGAA IUGGGCUA
14867





6895
AAGAAUGC A AACAUCAA
5528
UUGAUGUU CUGAUGAGGCCGUUAGGCCGAA ICAUUCUU
14868





6899
AUGCAAAC A UCAAACAG
5529
CUGUUUGA CUGAUGAGGCCGUUAGGCCGAA IUUUGCAU
14869





6902
CAAACAUC A AACAGAUA
5530
UAUCUGUU CUGAUGAGGCCGUUAGGCCGAA IAUGUUUG
14870





6906
CAUCAAAC A GAUACUCG
5531
CGAGUAUC CUGAUGAGGCCGUUAGGCCGAA IUUUGAUG
14871





6912
ACAGAUAC U CGCUAGCC
5532
GGCUAGCG CUGAUGAGGCCGUUAGGCCGAA IUAUCUGU
14872





6916
AUACUCGC U AGCCUCAU
5533
AUGAGGCU CUGAUGAGGCCGUUAGGCCGAA ICGAGUAU
14873





6920
UCGCUAGC C UCAUUUAA
5534
UUAAAUGA CUGAUGAGGCCGUUAGGCCGAA ICUAGCGA
14874





6921
CGCUAGCC U CAUUUAAA
5535
UUUAAAUG CUGAUGAGGCCGUUAGGCCGAA IGCUAGCG
14875





6923
CUAGCCUC A UUUAAAUU
5536
AAUUUAAA CUGAUGAGGCCGUUAGGCCGAA IAGGCUAG
14876





6949
AGGAGUGC A UCUUUGGC
5537
GCCAAAGA CUGAUGAGGCCGUUAGGCCGAA ICACUCCU
14877





6952
AGUGCAUC U UUGGCCGA
5538
UCGGCCAA CUGAUGAGGCCGUUAGGCCGAA IAUGCACU
14878





6958
UCUUUGGC C GACAGUGG
5539
CCACUGUC CUGAUGAGGCCGUUAGGCCGAA ICCAAAGA
14879





6962
UGGCCGAC A GUGGUGUA
5540
UACACCAC CUGAUGAGGCCGUUAGGCCGAA IUCGGCCA
14880





6973
GGUGUAAC U GUGUGUGU
5541
ACACACAC CUGAUGAGGCCGUUAGGCCGAA IUUACACC
14881





7041
UUUUGUGC A UAACUAUU
5542
AAUAGUUA CUGAUGAGGCCGUUAGGCCGAA ICACAAAA
14882





7046
UGCAUAAC U AUUUAAGG
5543
CCUUAAAU CUGAUGAGGCCGUUAGGCCGAA IUUAUGCA
14883





7059
AAGGAAAC U GGAAUUUU
5544
AAAAUUCC CUGAUGAGGCCGUUAGGCCGAA IUUUCCUU
14884





7076
AAAGUUAC U UUUAUACA
5545
UGUAUAAA CUGAUGAGGCCGUUAGGCCGAA IUAACUUU
14885





7084
UUUUAUAC A AACCAAGA
5546
UCUUGGUU CUGAUGAGGCCGUUAGGCCGAA IUAUAAAA
14886





7088
AUACAAAC C AAGAAUAU
5547
AUAUUCUU CUGAUGAGGCCGUUAGGCCGAA IUUUGUAU
14887





7089
UACAAACC A AGAAUAUA
5548
UAUAUUCU CUGAUGAGGCCGUUAGGCCGAA IGUUUGUA
14888





7101
AUAUAUGC U ACAGAUAU
5549
AUAUCUGU CUGAUGAGGCCGUUAGGCCGAA ICAUAUAU
14889





7104
UAUGCUAC A GAUAUAAG
5550
CUUAUAUC CUGAUGAGGCCGUUAGGCCGAA IUAGCAUA
14890





7115
UAUAAGAC A GACAUGGU
5551
ACCAUGUC CUGAUGAGGCCGUUAGGCCGAA IUCUUAUA
14891





7119
AGACAGAC A UGGUUUGG
5552
CCAAACCA CUGAUGAGGCCGUUAGGCCGAA IUCUGUCU
14892





7130
GUUUGGUC C UAUAUUUC
5553
GAAAUAUA CUGAUGAGGCCGUUAGGCCGAA IACCAAAC
14893





7131
UUUGGUCC U AUAUUUCU
5554
AGAAAUAU CUGAUGAGGCCGUUAGGCCGAA IGACCAAA
14894





7139
UAUAUUUC U AGUCAUGA
5555
UCAUGACU CUGAUGAGGCCGUUAGGCCGAA IAAAUAUA
14895





7144
UUCUAGUC A UGAUGAAU
5556
AUUCAUCA CUGAUGAGGCCGUUAGGCCGAA IACUAGAA
14896





7166
UUGUAUAC C AUCUUCAU
5557
AUGAAGAU CUGAUGAGGCCGUUAGGCCGAA IUAUACAA
14897





7167
UGUAUACC A UCUUCAUA
5558
UAUGAAGA CUGAUGAGGCCGUUAGGCCGAA IGUAUACA
14898





7170
AUACCAUC U UCAUAUAA
5559
UUAUAUGA CUGAUGAGGCCGUUAGGCCGAA IAUGGUAU
14899





7173
CCAUCUUC A UAUAAUAU
5560
AUAUUAUA CUGAUGAGGCCGUUAGGCCGAA IAAGAUGG
14900





7184
UAAUAUAC U UAAAAAUA
5561
UAUUUUUA CUGAUGAGGCCGUUAGGCCGAA IUAUAUUA
14901





7197
AAUAUUUC U UAAUUGGG
5562
CCCAAUUA CUGAUGAGGCCGUUAGGCCGAA IAAAUAUU
14902





7220
AAUCGUAC C AACUUAAU
5563
AUUAAGUU CUGAUGAGGCCGUUAGGCCGAA IUACGAUU
14903





7221
AUCGUACC A ACUUAAUU
5564
AAUUAAGU CUGAUGAGGCCGUUAGGCCGAA IGUACGAU
14904





7224
GUACCAAC U UAAUUGAU
5565
AUCAAUUA CUGAUGAGGCCGUUAGGCCGAA IUUGGUAC
14905





7237
UGAUAAAC U UGGCAACU
5566
AGUUGCCA CUGAUGAGGCCGUUAGGCCGAA ICUUAUCA
14906





7242
AACUUGGC A ACUGCUUU
5567
AAAGCAGU CUCAUGAGGCCGUUAGGCCGAA ICCAAGUU
14907





7245
UUGGCAAC U GCUUUUAU
5568
AUAAAAGC CUGAUGAGGCCGUUAGGCCGAA IUUGCCAA
14908





7248
GCAACUGC U UUUAUGUU
5569
AACAUAAA CUGAUGAGGCCGUUAGGCCGAA ICAGUUGC
14909





7258
UUAUGUUC U GUCUCCUU
5570
AAGGAGAC CUGAUGAGGCCGUUAGGCCGAA IAACAUAA
14910





7262
GUUCUGUC U CCUUCCAU
5571
AUGGAAGG CUGAUGAGGCCGUUAGGCCGAA IACAGAAC
14911





7264
UCUGUCUC C UUCCAUAA
5572
UUAUGGAA CUGAUGAGGCCGUUAGGCCGAA IAGACAGA
14912





7265
CUGUCUCC U UCCAUAAA
5573
UUUAUGGA CUGAUGAGGCCGUUAGGCCGAA IGAGACAG
14913





7268
UCUCCUUC C AUAAAUUU
5574
AAAUUUAU CUGAUGAGGCCGUUAGGCCGAA IAAGGAGA
14914





7269
CUCCUUCC A UAAAUUUU
5575
AAAAUUUA CUGAUGAGGCCGUUAGGCCGAA IGAAGGAG
14915





7280
AAUUUUUC A AAAUACUA
5576
UAGUAUUU CUGAUGAGGCCGUUAGGCCGAA IAAAAAUU
14916





7287
CAAAAUAC U AAUUCAAC
5577
GUUGAAUU CUGAUGAGGCCGUUAGGCCGAA IUAUUUUG
14917





7293
ACUAAUUC A ACAAAGAA
5578
UUCUUUGU CUGAUGAGGCCGUUAGGCCGAA IAAUUAGU
14918





7296
AAUUCAAC A AAGAAAAA
5579
UUUUUCUU CUGAUGAGGCCGUUAGGCCGAA IUUGAAUU
14919





7307
GAAAAAGC U CUUUUUUU
5580
AAAAAAAG CUGAUGAGGCCGUUAGGCCGAA ICUUUUUC
14920





7309
AAAAGCUC U UUUUUUUC
5581
GAAAAAAA CUGAUGAGGCCGUUAGGCCGAA IAGCUUUU
14921





7318
UUUUUUUC C UAAAAUAA
5582
UUAUUUUA CUGAUGAGGCCGUUAGGCCGAA IAAAAAAA
14922





7319
UUUUUUCC U AAAAUAAA
5583
UUUAUUUU CUGAUGAGGCCGUUAGGCCGAA IGAAAGAA
14923





7329
AAAUAAAC U CAAAUUUA
5584
UAAAUUUG CUGAUGAGGCCGUUAGGCCGAA IUUUAUUU
14924





7331
AUAAACUC A AAUUUAUC
5585
GAUAAAUU CUGAUGAGGCCGUUAGGCCGAA IAGUUUAU
14925





7340
AAUUUAUC C UUGUUUAG
5586
CUAAACAA CUGAUGAGGCCGUUAGGCCGAA IAUAAAUU
14926





7341
AUUUAUCC U UGUUUAGA
5587
UCUAAACA CUGAUGAGGCCGUUAGGCCGAA IGAUAAAU
14927





7352
UUUAGAGC A GAGAAAAA
5588
UUUUUCUC CUGAUGAGGCCGUUAGGCCGAA ICUCUAAA
14928





7372
AGAAAAAC U UUGAAAUG
5589
CAUUUCAA CUGAUGAGGCCGUUAGGCCGAA IUUUUUCU
14929





7384
AAAUGGUC U CAAAAAAU
5590
AUUUUUUG CUGAUGAGGCCGUUAGGCCGAA IACCAUUU
14930





7386
AUGGUCUC A AAAAAUUG
5591
CAAUUUUU CUGAUGAGGCCGUUAGGCCGAA IAGACCAU
14931





7396
AAAAUUGC U AAAUAUUU
5592
AAAUAUUU CUGAUGAGGCCGUUAGGCCGAA ICAAUUUU
14932





7407
AUAUUUUC A AUGGAAAA
5593
UUUUCCAU CUGAUGAGGCCGUUAGGCCGAA IAAAAUAU
14933





7417
UGGAAAAC U AAAUGUUA
5594
UAACAUUU CUGAUGAGGCCGUUAGGCCGAA IUUUUCCA
14934





7433
AGUUUAGC U GAUUGUAU
5595
AUACAAUC CUGAUGAGGCCGUUAGGCCGAA ICUAAACU
14935





7455
UUUCGAAC C UUUCACUU
5596
AAGUGAAA CUGAUGAGGCCGUUAGGCCGAA IUUCGAAA
14936





7456
UUCGAACC U UUCACUUU
5597
AAAGUGAA CUGAUGAGGCCGUUAGGCCGAA IGUUCGAA
14937





7460
AACCUUUC A CUUUUUGU
5598
ACAAAAAG CUGAUGAGGCCGUUAGGCCGAA IAAAGGUU
14938





7462
CCUUUCAC U UUUUGUUU
5599
AAACAAAA CUGAUGAGGCCGUUAGGCCGAA IUGAAAGG
14939





7478
UGUUUUAC C UAUUUCAC
5600
GUGAAAUA CUGAUGAGGCCGUUAGGCCGAA IUAAAACA
14940





7479
GUUUUACC U AUUUCACA
5601
UGUGAAAU CUGAUGAGGCCGUUAGGCCGAA IGUAAAAC
14941





7485
CCUAUUUC A CAACUGUG
5602
CACAGUUG CUGAUGAGGCCGUUAGGCCGAA IAAAUAGG
14942





7487
UAUUUCAC A ACUGUGUA
5603
UACACAGU CUGAUGAGGCCGUUAGGCCGAA IUGAAAUA
14943





7490
UUCACAAC U GUGUAAAU
5604
AUUUACAC CUGAUGAGGCCGUUAGGCCGAA IUUGUGAA
14944





7502
UAAAUUGC C AAUAAUUC
5605
GAAUUAUU CUGAUGAGGCCGUUAGGCCGAA ICAAUUUA
14945





7503
AAAUUGCC A AUAAUUCC
5606
GGAAUUAU CUGAUGAGGCCGUUAGGCCGAA IGCAAUUU
14946





7511
AAUAAUUC C UGUCCAUG
5607
CAUGGACA CUGAUGAGGCCGUUAGGCCGAA IAAUUAUU
14947





7512
AUAAUUCC U GUCCAUGA
5608
UCAUGGAC CUGAUGAGGCCGUUAGGCCGAA IGAAUUAU
14948





7516
UUCCUGUC C AUGAAAAU
5609
AUUUUCAU CUGAUGAGGCCGUUAGGCCGAA IACAGGAA
14949





7517
UCCUGUCC A UGAAAAUG
5610
CAUUUUCA CUGAUGAGGCCGUUAGGCCGAA IGACAGGA
14950





7527
GAAAAUGC A AAUUAUCC
5611
GGAUAAUU CUGAUGAGGCCGUUAGGCCGAA ICAUUUUC
14951





7535
AAAUUAUC C AGUGUAGA
5612
UCUACACU CUGAUGAGGCCGUUAGGCCGAA IAUAAUUU
14952





7536
AAUUAUCC A GUGUAGAU
5613
AUCUACAC CUGAUGAGGCCGUUAGGCCGAA IGAUAAUU
14953





7554
UAUUUGAC C AUCACCCU
5614
AGGGUGAU CUGAUGAGGCCGUUAGGCCGAA IUCAAAUA
14954





7555
AUUUGACC A UCACCCUA
5615
UAGGGUGA CUGAUGAGGCCGUUAGGCCGAA IGUCAAAU
14955





7558
UGACCAUC A CCCUAUGG
5616
CCAUAGGG CUGAUGAGGCCGUUAGGCCGAA IAUGGUCA
14956





7560
ACCAUCAC C CUAUGGAU
5617
AUCCAUAG CUGAUGAGGCCGUUAGGCCGAA IUGAUGGU
14957





7561
CCAUCACC C UAUGGAUA
5618
UAUCCAUA CUGAUGAGGCCGUUAGGCCGAA IGUGAUGG
14958





7562
CAUCACCC U AUGGAUAU
5619
AUAUCCAU CUGAUGAGGCCGUUAGGCCGAA IGGUGAUG
14959





7575
AUAUUGGC U AGUUUUGC
5620
GCAAAACU CUGAUGAGGCCGUUAGGCCGAA ICCAAUAU
14960





7584
AGUUUUGC C UUUAUUAA
5621
UUAAUAAA CUGAUGAGGCCGUUAGGCCGAA ICAAAACU
14961





7585
GUUUUGCC U UUAUUAAG
5622
CUUAAUAA CUGAUGAGGCCGUUAGGCCGAA IGCAAAAC
14962





7595
UAUUAAGC A AAUUCAUU
5623
AAUGAAUU CUGAUGAGGCCGUUAGGCCGAA ICUUAAUA
14963





7601
GCAAAUUC A UUUCAGCC
5624
GGCUGAAA CUGAUGAGGCCGUUAGGCCGAA IAAUUUGC
14964





7606
UUCAUUUC A GCCUGAAU
5625
AUUCAGGC CUGAUGAGGCCGUUAGGCCGAA IAAAUGAA
14965





7609
AUUUCAGC C UGAAUGUC
5626
GACAUUCA CUGAUGAGGCCGUUAGGCCGAA ICUGAAAU
14966





7610
UUUCAGCC U GAAUGUCU
5627
AGACAUUC CUGAUGAGGCCGUUAGGCCGAA IGCUGAAA
14967





7618
UGAAUGUC U GCCUAUAU
5628
AUAUAGGC CUGAUGAGGCCGUUAGGCCGAA IACAUUCA
14968





7621
AUGUCUGC C UAUAUAUU
5629
AAUAUAUA CUGAUGAGGCCGUUAGGCCGAA ICAGACAU
14969





7622
UGUCUGCC U AUAUAUUC
5630
GAAUAUAU CUGAUGAGGCCGUUAGGCCGAA IGCAGACA
14970





7631
AUAUAUUC U CUGCUCUU
5631
AAGAGCAG CUGAUGAGGCCGUUAGGCCGAA IAAUAUAU
14971





7633
AUAUUCUC U GCUCUUUG
5632
CAAAGAGC CUGAUGAGGCCGUUAGGCCGAA IAGAAUAU
14972





7636
UUCUCUGC U CUUUGUAU
5633
AUACAAAG CUGAUGAGGCCGUUAGGCCGAA ICAGAGAA
14973





7638
CUCUGCUC U UUGUAUUC
5634
GAAUACAA CUGAUGAGGCCGUUAGGCCGAA IAGCAGAG
14974





7647
UUGUAUUC U CCUUUGAA
5635
UUCAAAGG CUGAUGAGGCCGUUAGGCCGAA IAAUACAA
14975





7649
GUAUUCUC C UUUGAACC
5636
GGUUCAAA CUGAUGAGGCCGUUAGGCCGAA IAGAAUAC
14976





7650
UAUUCUCC U UUGAACCC
5637
GGGUUCAA CUGAUGAGGCCGUUAGGCCGAA IGAGAAUA
14977





7657
CUUUGAAC C CGUUAAAA
5638
UUUUAACG CUGAUGAGGCCGUUAGGCCGAA IUUCAAAG
14978





7658
UUUGAACC C GUUAAAAC
5639
GUUUUAAC CUGAUGAGGCCGUUAGGCCGAA IGUUCAAA
14979





7667
GUUAAAAC A UCCUGUGG
5640
CCACAGGA CUGAUGAGGCCGUUAGGCCGAA IUUUUAAC
14980





7670
AAAACAUC C UGUGGCAC
5641
GUGCCACA CUGAUGAGGCCGUUAGGCCGAA IAUGUUUU
14981





7671
AAACAUCC U GUGGCACU
5642
AGUGCCAC CUGAUGAGGCCGUUAGGCCGAA IGAUGUUU
14982






Core Sequence = CUGAUGAG GCCGUUAGGC CGAA.




Underlined region can be any X sequence or linker, as described herein.




“I” represents Inosine.








[0354]

18






TABLE XV










G-Cleaver Ribozyme and Target Sequences















Seq ID

Seq ID



Pos
Target
No
Ribozyme Sequence
No















67
GGGCUCGGGU G CAGCG
5643
CGCUG UGAUG GCAUGCACUAUGC GCG ACCCGAGCCC
14983






91
GCCUGGCGGC G AGGAU
5644
AUCCU UGAUG GCAUGCACUAUGC GCG GCCGCCAGGC
14984





114
GGAAGUGGUU G UCUCC
5645
GGAGA UGAUG GCAUGCACUAUGC GCG AACCACUUCC
14985





131
GGCUGGAGCC G CGAGA
5646
UCUCG UGAUG GCAUGCACUAUGC GCG GGCUCCAGCC
14986





133
CUGGAGCCGC G AGACG
5647
CGUCU UGAUG GCAUGCACUAUGC GCG GCGGCUCCAG
14987





142
CGAGACGGGC G CUCAG
5648
CUGAG UGAUG GCAUGCACUAUGC GCG GCCCGUCUCG
14988





151
CGCUCAGGGC G CGGGG
5649
CCCCG UGAUG GCAUGCACUAUGC GCG GCCCUGAGCG
14989





168
CGGCGGCGGC G AACGA
5650
UCGUU UGAUG GCAUGCACUAUGC GCG GCCGCCGCCG
14990





172
GGCGGCGAAC G AGAGG
5651
CCUCU UGAUG GCAUGCACUAUGC GCG GUUCGCCGCC
14991





214
CCGGGGGAGC G CGGGC
5652
GCCCG UGAUG GCAUGCACUAUGC GCG GCUCCCCCGG
14992





227
GGCACCGGGC G AGCAG
5653
CUGCU UGAUG GCAUGCACUAUGC GCG GCCCGGUGCC
14993





236
CGAGCAGGCC G CGUCG
5654
CGACG UGAUG GCAUGCACUAUGC GCG GGCCUGCUCG
14994





241
AGGCCGCGUC G CGCUC
5655
GAGCG UGAUG GCAUGCACUAUGC GCG GACGCGGCCU
14995





243
GCCGCGUCGC G CUCAC
5656
GUGAG UGAUG GCAUGCACUAUGC GCG GCGACGCGGC
14996





279
CCGGGGUCCU G CUGUG
5657
CACAG UGAUG GCAUGCACUAUGC GCG AGGACCCCGG
14997





282
GGGUCCUGCU G UGCGC
5658
GCGCA UGAUG GCAUGCACUAUGC GCG AGCAGGACCC
14998





284
GUCCUGCUGU G CGCGC
5659
GCGCG UGAUG GCAUGCACUAUGC GCG ACAGCAGGAC
14999





286
CCUGCUGUGC G CGCUG
5660
CAGCG UGAUG GCAUGCACUAUGC GCG GCACAGCAGG
15000





288
UGCUGUGCGC G CUGCU
5661
AGCAG UGAUG GCAUGCACUAUGC GCG GCGCACAGCA
15001





291
UGUGCGCGCU G CUCAG
5662
CUGAG UGAUG GCAUGCACUAUGC GCG AGCGCGCACA
15002





299
CUGCUCAGCU G UCUGC
5663
GCAGA UGAUG GCAUGCACUAUGC GCG AGCUGAGCAG
15003





303
UCAGCUGUCU G CUUCU
5664
AGAAG UGAUG GCAUGCACUAUGC GCG AGACAGCUGA
15004





346
AAAAGAUCCU G AACUG
5665
CAGUU UGAUG GCAUGCACUAUGC GCG AGGAUCUUUU
15005





351
AUCCUGAACU G AGUUU
5666
AAACU UGAUG GCAUGCACUAUGC GCG AGUUCAGGAU
15006





378
AGCACAUCAU G CAAGC
5667
GCUUG UGAUG GCAUGCACUAUGC GCG AUGAUGUGCU
15007





396
GCCAGACACU G CAUCU
5668
AGAUG UGAUG GCAUGCACUAUGC GCG AGUGUCUGGC
15008





407
CAUCUCCAAU G CAGGG
5669
CCCUG UGAUG GCAUGCACUAUGC GCG AUUGGAGAUG
15009





438
AAUGGUCUUU G CCUGA
5670
UCAGG UGAUG GCAUGCACUAUGC GCG AAAGACCAUU
15010





442
GUCUUUGCCU G AAAUG
5671
CAUUU UGAUG GCAUGCACUAUGC GCG AGGCAAAGAC
15011





450
CUGAAAUGGU G AGUAA
5672
UUACU UGAUG GCAUGCACUAUGC GCG ACCAUUUCAG
15012





463
UAAGGAAAGC G AAAGG
5673
CCUUU UGAUG GCAUGCACUAUGC GCG GCUUUCCUUA
15013





471
GCGAAAGGCU G AGCAU
5674
AUGCU UGAUG GCAUGCACUAUGC GCG AGCCUUUCGC
15014





487
AACUAAAUCU G CCUGU
5675
ACAGG UGAUG GCAUGCACUAUGC GCG AGAUUUAGUU
15015





491
AAAUCUGCCU G UGGAA
5676
UUCCA UGAUG GCAUGCACUAUGC GCG AGGCAGAUUU
15016





515
AAACAAUUCU G CAGUA
5677
UACUG UGAUG GCAUGCACUAUGC GCG AGAAUUGUUU
15017





531
CUUUAACCUU G AACAC
5678
GUGUU UGAUG GCAUGCACUAUGC GCG AAGGUUAAAG
15018





569
UUCUACAGCU G CAAAU
5679
AUUUG UGAUG GCAUGCACUAUGC GCG AGCUGUAGAA
15019





583
AUAUCUAGCU G UACCU
5680
AGGUA UGAUG GCAUGCACUAUGC GCG AGCUAGAUAU
15020





616
AACAGAAUCU G CAAUC
5681
GAUUG UGAUG GCAUGCACUAUGC GCG AGAUUCUGUU
15021





637
AUUUAUUAGU G AUACA
5682
UGUAU UGAUG GCAUGCACUAUGC GCG ACUAAUAAAU
15022





663
UCGUAGAGAU G UACAG
5683
CUGUA UGAUG GCAUGCACUAUGC GCG AUCUCUACGA
15023





670
GAUGUACAGU G AAAUC
5684
GAUUU UGAUG GCAUGCACUAUGC GCG ACUGUACAUC
15024





679
UGAAAUCCCC G AAAUU
5685
AAUUU UGAUG GCAUGCACUAUGC GCG GGGGAUUUCA
15025





693
UUAUACACAU G ACUGA
5686
UCAGU UGAUG GCAUGCACUAUGC GCG AUGUGUAUAA
15026





697
ACACAUGACU G AAGGA
5687
UCCUU UGAUG GCAUGCACUAUGC GCG AGUCAUGUGU
15027





722
GUCAUUCCCU G CCGGG
5688
CCCGG UGAUG GCAUGCACUAUGC GCG AGGGAAUGAC
15028





748
UAACAUCACU G UUACU
5689
AGUAA UGAUG GCAUGCACUAUGC GCG AGUGAUGUUA
15029





772
GUUUCCACUU G ACACU
5690
AGUGU UGAUG GCAUGCACUAUGC GCG AAGUGGAAAC
15030





780
UUGACACUUU G AUCCC
5691
GCGAU UGAUG GCAUGCACUAUGC GCG AAAGUGUCAA
15031





787
UUUGAUCCCU G AUGGA
5692
UCCAU UGAUG GCAUGCACUAUGC GCG AGGGAUCAAA
15032





797
GAUGGAAAAC G CAUAA
5693
UUAUC UGAUG GCAUGCACUAUGC GCG GUUUUCCAUC
15033





838
CAUAUCAAAU G CAACG
5694
CGUUG UGAUG GCAUGCACUAUGC GCG AUUUGAUAUG
15034





864
UAGGGCUUCU G ACCUG
5695
CAGGU UGAUG GCAUGCACUAUGC GCG AGAAGCCCUA
15035





869
CUUCUGACCU G UGAAG
5696
CUUCA UGAUG GCAUGCACUAUGC GCG AGGUCAGAAG
15036





871
UCUGACCUGU G AAGCA
5697
UGCUU UGAUG GCAUGCACUAUGC GCG ACAGGUCAGA
15037





894
AUGGGCAUUU G UAUAA
5698
UUAUA UGAUG GCAUGCACUAUGC GCG AAAUGCCCAU
15038





920
CUCACACAUC G ACAAA
5699
UUUGU UGAUG GCAUGCACUAUCC GCG GAUGUGUGAG
15039





943
AAUCAUAGAU G UCCAA
5700
UUGGA UGAUG GCAUGCACUAUGC GCG AUCUAUGAUU
15040





962
AGCACACCAC G CCCAG
5701
CUGGG UGAUG GCAUGCACUAUGC GCG GUGGUGUGCU
15041





994
CCAUACUCUU G UCCUC
5702
GAGGA UGAUG GCAUGCACUAUGC GCG AAGAGUAUGG
15042





1004
GUCCUCAAUU G UACUG
5703
CAGUA UGAUG GCAUGCACUAUGC GCG AAUUGAGGAC
15043





1009
CAAUUGUACU G CUACC
5704
GGUAG UGAUG GCAUGCACUAUGC GCG AGUACAAUUG
15044





1023
CCACUCCCUU G AACAC
5705
GUGUU UGAUG GCAUGCACUAUGC GCG AAGGGAGUGG
15045





1029
CCUUGAACAC G AGAGU
5706
ACUCU UGAUG GCAUGCACUAUGC GCG GUGUUCAAGG
15046





1041
GAGUUCAAAU G ACCUG
5707
CAGGU UGAUG GCAUGCACUAUGC GCG AUUUGAACUC
15047





1057
GAGUUACCCU G AUGAA
5708
UUCAU UGAUG GCAUGCACUAUGC GCG AGGGUAACUC
15048





1060
UUACCCUGAU G AAAAA
5709
UUUUU UGAUG GCAUGCACUAUGC GCG AUCAGGGUAA
15049





1088
UCCGUAAGGC G ACGAA
5710
UUCGU UGAUG GCAUGCACUAUGC GCG GCCUUACGGA
15050





1091
GUAAGGCGAC G AAUUG
5711
CAAUU UGAUG GCAUGCACUAUGC GCG GUCGCCUUAC
15051





1096
GCGACGAAUU G ACCAA
5712
UUGGU UGAUG GCAUGCACUAUGC GCG AAUUCGUCGC
15052





1114
CAAUUCCCAU G CCAAC
5713
GUUGG UGAUG GCAUGCACUAUGC GCG AUGGGAAUUG
15053





1132
AUUCUACAGU G UUCUU
5714
AAGAA UGAUG GCAUGCACUAUGC GCG ACUGUAGAAU
15054





1144
UCUUACUAUU G ACAAA
5715
UUUGU UGAUG GCAUGCACUAUGC GCG AAUAGUAAGA
15055





1152
UUGACAAAAU G CAGAA
5716
UUCUG UGAUG GCAUGCACUAUGC GCG AUUUUGUCAA
15056





1181
CUUUAUACUU G UCGUG
5717
CACGA UGAUG GCAUGCACUAUGC GCG AAGUAUAAAG
15057





1186
UACUUGUCGU G UAAGG
5718
CCUUA UGAUG GCAUGCACUAUGC GCG ACGACAAGUA
15058





1213
AUUCAAAUCU G UUAAC
5719
GUUAA UGAUG GCAUGCACUAUGC GCG AGAUUUGAAU
15059





1227
ACACCUCAGU G CAUAU
5720
AUAUG UGAUG GCAUGCACUAUGC GCG ACUGAGGUGU
15060





1237
GCAUAUAUAU G AUAAA
5721
UUUAU UGAUG GCAUGCACUAUGC GCG AUAUAUAUGC
15061





1255
AUUCAUCACU G UGAAA
5722
UUUCA UGAUG GCAUGCACUAUGC GCG AGUGAUGAAU
15062





1257
UCAUCACUGU G AAACA
5723
UGUUU UGAUG GCAUGCACUAUGC GCG ACAGUGAUGA
15063





1265
GUGAAACAUC G AAAAC
5724
GUUUU UGAUG GCAUGCACUAUGC GCG GAUGUUUCAC
15064





1278
AACAGCAGGU G CUUGA
5725
UCAAG UGAUG GCAUGCACUAUGC GCG ACCUGCUGUU
15065





1282
GCAGGUGCUU G AAACC
5726
GGUUU UGAUG GCAUGCACUAUGC GCG AAGCACCUGC
15066





1320
GGCUCUCUAU G AAAGU
5727
ACUUU UGAUG GCAUGCACUAUGC GCG AUAGAGAGCC
15067





1326
CUAUGAAAGU G AAGGC
5728
GCCUU UGAUG GCAUGCACUAUGC GCG ACUUUCAUAG
15068





1341
CAUUUCCCUC G CCGGA
5729
UCCGG UGAUG GCAUGCACUAUGC GCG GAGGGAAAUG
15069





1351
GCCGGAAGUU G UAUGG
5730
CCAUA UGAUG GCAUGCACUAUGC GCG AACUUCCGGC
15070





1375
UGGGUUACCU G CGACU
5731
AGUCG UGAUG GCAUGCACUAUGC GCG AGGUAACCCA
15071





1377
GGUUACCUGC G ACUGA
5732
UCAGU UGAUG GCAUGCACUAUGC GCG GCAGGUAACC
15072





1381
ACCUGCGACU G AGAAA
5733
UUUCU UGAUG GCAUGCACUAUGC GCG AGUCGCAGGU
15073





1390
UGAGAAAUCU G CUCGC
5734
GCGAG UGAUG GCAUGCACUAUGC GCG AGAUUUCUCA
15074





1394
AAAUCUGCUC G CUAUU
5735
AAUAG UGAUG GCAUGCACUAUGC GCG GAGCAGAUUU
15075





1401
CUCGCUAUUU G ACUCG
5736
CGAGU UGAUG GCAUGCACUAUGC GCG AAAUAGCGAG
15076





1438
GGACGUAACU G AAGAG
5737
CUCUU UGAUG GCAUGCACUAUGC GCG AGUUACGUCC
15077





1447
UGAAGAGGAU G CAGGG
5738
CCCUG UGAUG GCAUGCACUAUGC GCG AUCCUCUUCA
15078





1467
AUACAAUCUU G CUGAG
5739
CUCAG UGAUG GCAUGCACUAUGC GCG AAGAUUGUAU
15079





1470
CAAUCUUGCU G AGCAU
5740
AUGCU UGAUG GCAUGCACUAUGC GCG AGCAAGAUUG
15080





1489
ACAGUCAAAU G UGUUU
5741
AAACA UGAUG GCAUGCACUAUGC GCG AUUUGACUGU
15081





1491
AGUCAAAUGU G UUUAA
5742
UUAAA UGAUG GCAUGCACUAUGC GCG ACAUUUGACU
15082





1507
AAACCUCACU G CCACU
5743
AGUGG UGAUG GCAUGCACUAUGC GCG AGUGAGGUUG
15083





1519
CACUCUAAUU G UCAAU
5744
AUUGA UGAUG GCAUGCACUAUGC GCG AAUUAGAGUG
15084





1525
AAUUGUCAAU G UGAAA
5745
UGUCA UGAUG GCAUGCACUAUGC GCG AUUGACAAUU
15085





1527
UUGUCAAUGU G AAACC
5746
GGUUU UGAUG GCAUGCACUAUGC GCG ACAUUGACAA
15086





1543
CCAGAUUUAC G AAAAG
5747
CUUUU UGAUG GCAUGCACUAUGC GCG GUAAAUCUGG
15087





1554
AAAAGGCCGU G UCAUC
5748
GAUGA UGAUG GCAUGCACUAUGC GCG ACGGCCUUUU
15088





1605
GACAAAUCCU G ACUUG
5749
CAAGU UGAUG GCAUGCACUAUGC GCG AGGAUUUGUC
15089





1610
AUCCUGACUU G UACCG
5750
CGGUA UGAUG GCAUGCACUAUGC GCG AAGUCAGGAU
15090





1615
GACUUGUACC G CAUAU
5751
AUAUG UGAUG GCAUGCACUAUGC GCG GGUACAAGUC
15091





1661
UGGCACCCCU G UAACC
5752
GGUUA UGAUG GCAUGCACUAUGC GCG AGGGGUGCCA
15092





1678
UAAUCAUUCC G AAGCA
5753
UGCUU UGAUG GCAUGCACUAUGC GCG GGAAUGAUUA
15093





1688
GAAGCAAGGU G UGACU
5754
AGUCA UGAUG GCAUGCACUAUGC GCG ACCUUGCUUC
15094





1690
AGCAAGGUGU G ACUUU
5755
AAAGU UGAUG GCAUGCACUAUGC GCG ACACCUUGCU
15095





1697
UGUGACUUUU G UUCCA
5756
UGGAA UGAUG GCAUGCACUAUGC GCG AAAAGUCACA
15096





1708
UUCCAAUAAU G AAGAG
5757
CUCUU UGAUG GCAUGCACUAUGC GCG AUUAUUGGAA
15097





1729
UAUCCUGGAU G CUGAC
5758
GUCAG UGAUG GCAUGCACUAUGC GCG AUCCAGGAUA
15098





1732
CCUGGAUGCU G ACAGC
5759
GCUGU UGAUG GCAUGCACUAUGC GCG AGCAUCCAGG
15099





1756
AAACAGAAUU G AGAGC
5760
GCUCU UGAUG GCAUGCACUAUGC GCG AAUUCUGUUU
15100





1772
AUCACUCAGC G CAUGG
5761
CCAUG UGAUG GCAUGCACUAUGC GCG GCUGAGUGAU
15101





1819
CACCUGGGUU G UGGCU
5762
AGCCA UGAUG GCAUGCACUAUGC GCG AACCAAGGUG
15102





1825
GGUUGUGGCU G ACUCU
5763
AGAGU UGAUG GCAUGCACUAUGC GCG AGCCACAACC
15103





1853
AUCUACAUUU G CAUAG
5764
CUAUG UGAUG GCAUGCACUAUGC GCG AAAUGUAGAU
15104





1879
AGUUGGGACU G UGGGA
5765
UCCCA UGAUG GCAUGCACUAUGC GCG AGUCCCAACU
15105





1912
UAUCACAGAU G UGCCA
5766
UGGCA UGAUG GCAUGCACUAUGC GCG AUCUGUGAUA
15106





1914
UCACAGAUGU G CCAAA
5767
UUUGG UGAUG GCAUGCACUAUGC GCG ACAUCUGUGA
15107





1930
UGGGUUUCAU G UUAAC
5768
GUUAA UGAUG GCAUGCACUAUGC GCG AUGAAACCCA
15108





1947
UGGAAAAAAU G CCGAC
5769
GUCGG UGAUG GCAUGCACUAUGC GCG AUUUUUUCCA
15109





1950
AAAAAAUGCC G ACGGA
5770
UCCGU UGAUG GCAUGCACUAUGC GCG GGCAUUUUUU
15110





1968
GAGAGGACCU G AAACU
5771
AGUUU UGAUG GCAUGCACUAUGC GCG AGGUCCUCUC
15111





1974
ACCUGAAACU G UCUUG
5772
CAAGA UGAUG GCAUGCACUAUGC GCG AGUUUCAGGU
15112





1979
AAACUGUCUU G CACAG
5773
CUGUG UGAUG GCAUGCACUAUGC GCG AAGACAGUUU
15113





2025
GGAUUUUACU G CGGAC
5774
GUCCG UGAUG GCAUGCACUAUGC GCG AGUAAAAUCC
15114





2049
ACAGAACAAU G CACUA
5775
UAGUG UGAUG GCAUGCACUAUGC GCG AUUGUUCUGU
15115





2121
UUACCAUCAU G AAUGU
5776
ACAUU UGAUG GCAUGCACUAUGC GCG AUGAUGGUAA
15116





2125
CAUCAUGAAU G UUUCC
5777
GGAAA UGAUG GCAUGCACUAUGC GCG AUUCAUGAUG
15117





2133
AUGUUUCCCU G CAAGA
5778
UCUUG UGAUG GCAUGCACUAUGC GCG AGGGAAACAU
15118





2152
AGGCACCUAU G CCUGC
5779
GCAGG UGAUG GCAUGCACUAUGC GCG AUAGGUGCCU
15119





2156
ACCUAUGCCU G CAGAG
5780
CUCUG UGAUG GCAUGCACUAUGC GCG AGGGAUAGGU
15120





2170
AGCCAGGAAU G UAUAC
5781
GUAUA UGAUG GCAUGCACUAUGC GCG AUUCCUGGCU
15121





2241
CAUACCUCCU G CGAAA
5782
UUUCG UGAUG GCAUGCACUAUGC GCG AGGAGGUAUG
15122





2243
UACCUCCUGC G AAACC
5783
GGUUU UGAUG GCAUGCACUAUGC GCG GCAGGAGGUA
15123





2254
AAACCUCAGU G AUCAC
5784
GUGAU UGAUG GCAUGCACUAUGC GCG ACUGAGGUUU
15124





2294
ACUUUAGACU G UCAUG
5785
CAUGA UGAUG GCAUGCACUAUGC GCG AGUCUAAAGU
15125





2299
AGACUGUCAU G CUAAU
5786
AUUAG UGAUG GCAUGCACUAUGC GCG AUGACAGUCU
15126





2308
UGCUAAUGGU G UCCCC
5787
GGGGA UGAUG GCAUGCACUAUGC GCG ACCAUUAGCA
15127





2314
UGGUGUCCCC G AGCCU
5788
AGGCU UGAUG GCAUGCACUAUGC GCG GGGGACACCA
15128





2394
GAAGCAGCAC G CUGUU
5789
AACAG UGAUG GCAUGCACUAUGC GCG GUGCUGCUUC
15129





2397
GCAGCACGCU G UUUAU
5790
AUAAA UGAUG GCAUGCACUAUGC GCG AGCGUGCUGC
15130





2404
GCUGUUUAUU G AAAGA
5791
UCUUU UGAUG GCAUGCACUAUGC GCG AAUAAACAGC
15131





2425
AGAAGAGGAU G AAGGU
5792
ACCUU UGAUG GCAUGCACUAUGC GCG AUCCUCUUCU
15132





2431
GGAUGAAGGU G UCUAU
5793
AUAGA UGAUG GCAUGCACUAUGC GCG ACCUUCAUCC
15133





2441
GUCUAUCACU G CAAAG
5794
CUUUG UGAUG GCAUGCACUAUGC GCG AGUGAUAGAC
15134





2467
GAAGGGCUCU G UGGAA
5795
UUCCA UGAUG GCAUGCACUAUGC GCG AGAGCCCUUC
15135





2491
AUACCUCACU G UUCAA
5796
UUGAA UGAUG GCAUGCACUAUGC GCG AGUGAGGUAU
15136





2526
AUCUGGAGCU G AUCAC
5797
GUGAU UGAUG GCAUGCACUAUGC GCG AGCUCCAGAU
15137





2540
ACUCUAACAU G CACCU
5798
AGGUG UGAUG GCAUGCACUAUGC GCG AUGUUAGAGU
15138





2546
ACAUGCACCU G UGUGG
5799
CCACA UGAUG GCAUGCACUAUGC GCG AGGUGCAUGU
15139





2548
AUGCACCUGU G UGGCU
5800
AGCCA UGAUG GCAUGCACUAUGC GCG ACAGGUGCAU
15140





2554
CUGUGUGGCU G CGACU
5801
AGUCG UGAUG GCAUGCACUAUGC GCG AGCCACACAG
15141





2556
GUGUGGCUGC G ACUCU
5802
AGAGU UGAUG GCAUGCACUAUGC GCG GCAGCCACAC
15142





2591
CUCCUUAUCC G AAAAA
5803
UUUUU UGAUG GCAUGCACUAUGC GCG GGAUAAGGAG
15143





2598
UCCGAAAAAU G AAAAG
5804
CUUUU UGAUG GCAUGCACUAUGC GCG AUUUUUCGGA
15144





2614
GUCUUCUUCU G AAAUA
5805
UAUUU UGAUG GCAUGCACUAUGC GCG AGAAGAAGAC
15145





2626
AAUAAAGACU G ACUAC
5806
GUAGU UGAUG GCAUGCACUAUGC GCG AGUCUUUAUU
15146





2656
GGACCCAGAU G AAGUU
5807
AACUU UGAUG GCAUGCACUAUGC GCG AUCUGGGUCC
15147





2671
UCCUUUGGAU G AGCAG
5808
CUGCU UGAUG GCAUGCACUAUGC GCG AUCCAAAGGA
15148





2678
GAUGAGCAGU G UGAGC
5809
GCUCA UGAUG GCAUGCACUAUGC GCG ACUGCUCAUC
15149





2680
UGAGCAGUGU G AGCGG
5810
CCGCU UGAUG GCAUGCACUAUGC GCG ACACUGCUCA
15150





2695
GCUCCCUUAU G AUGCC
5811
GGCAU UGAUG GCAUGCACUAUGC GCG AUAAGGGAGC
15151





2698
CCCUUAUGAU G CCAGC
5812
GCUGG UGAUG GCAUGCACUAUGC GCG AUCAUAAGGG
15152





2716
GUGGGAGUUU G CCCGG
5813
CCGGG UGAUG GCAUGCACUAUGC GCG AAACUCCCAC
15153





2813
UCACCUACGU G CCGGA
5814
UCCGG UGAUG GCAUGCACUAUGC GCG ACGUAGGUGA
15154





2821
GUGCCGGACU G UGGCU
5815
AGCCA UGAUG GCAUGCACUAUGC GCG AGUCCGGCAC
15155





2827
GACUGUGGCU G UGAAA
5816
UUUCA UGAUG GCAUGCACUAUGC GCG AGCCACAGUC
15156





2829
CUGUGGCUGU G AAAAU
5817
AUUUU UGAUG GCAUGCACUAUGC GCG ACAGCCACAG
15157





2835
CUGUGAAAAU G CUGAA
5818
UUCAG UGAUG GCAUGCACUAUGC GCG AUUUUCACAG
15158





2838
UGAAAAUGCU G AAAGA
5819
UCUUU UGAUG GCAUGCACUAUGC GCG AGCAUUUUCA
15159





2860
CACGGCCAGC G AGUAC
5820
GUACU UGAUG GCAUGCACUAUGC GCG GCUGGCCGUG
15160





2874
ACAAAGCUCU G AUGAC
5821
GUCAU UGAUG GCAUGCACUAUGC GCG AGAGCUUUGU
15161





2877
AAGCUCUGAU G ACUGA
5822
UCAGU UGAUG GCAUGCACUAUGC GCG AUCAGAGCUU
15162





2881
UCUGAUGACU G AGCUA
5823
UAGCU UGAUG GCAUGCACUAUGC GCG AGUCAUCAGA
15163





2895
UAAAAAUCUU G ACCCA
5824
UGGGU UGAUG GCAUGCACUAUGC GCG AAGAUUUUUA
15164





2916
GCCACCAUCU G AACGU
5825
ACGUU UGAUG GCAUGCACUAUGC GCG AGAUGGUGGC
15165





2931
UGGUUAACCU G CUGGG
5826
CCCAG UGAUG GCAUGCACUAUGC GCG AGGUUAACCA
15166





2942
CUGGGAGCCU G CACCA
5827
UGGUG UGAUG GCAUGCACUAUGC GCG AGGCUCCCAG
15167





2964
GAGGGCCUCU G AUGGU
5828
ACCAU UGAUG GCAUGCACUAUGC GCG AGAGGCCCUC
15168





2970
CUCUGAUGGU G AUUGU
5829
ACAAU UGAUG GCAUGCACUAUGC GCG ACCAUCAGAG
15169





2974
GAUGGUGAUU G UUGAA
5830
UUCAA UGAUG GCAUGCACUAUGC GCG AAUCACCAUC
15170





2977
GGUGAUUGUU G AAUAC
5831
GUAUU UGAUG GCAUGCACUAUGC GCG AACAAUCACC
15171





2984
GUUGAAUACU G CAAAU
5832
AUUUG UGAUG GCAUGCACUAUGC GCG AGUAUUCAAC
15172





3025
GAGCAAACGU G ACUUA
5833
UAAGU UGAUG GCAUGCACUAUGC GCG ACGUUUGCUC
15173





3049
CAACAAGGAU G CAGCA
5834
UGCUG UGAUG GCAUGCACUAUGC GCG AUCCUUGUUG
15174





3139
CACCAGCAGC G AAAGC
5835
GCUUU UGAUG GCAUGCACUAUGC GCG GCUGCUGGUG
15175





3148
CGAAAGCUUU G CGAGC
5838
GCUCG UGAUG GCAUGCACUAUGC GCG AAAGCUUUCG
15176





3150
AAAGCUUUGC G AGCUC
5837
GAGCU UGAUG GCAUGCACUAUGC GCG GCAAAGCUUU
15177





3180
AUAAAAGUCU G AGUGA
5838
UCACU UGAUG GCAUGCACUAUGC GCG AGACUUUUAU
15178





3184
AAGUCUGAGU G AUGUU
5839
AACAU UGAUG GCAUGCACUAUGC GCG ACUCAGACUU
15179





3187
UCUGAGUGAU G UUGAG
5840
CUCAA UGAUG GCAUGCACUAUGC GCG AUCACUCAGA
15180





3190
GAGUGAUGUU G AGGAA
5841
UUCCU UGAUG GCAUGCACUAUGC GCG AACAUCACUC
15181





3208
GGAGGAUUCU G ACGGU
5842
ACCGU UGAUG GCAUGCACUAUGC GCG AGAAUCCUCC
15182





3246
UGGAAGAUCU G AUUUC
5843
GAAAU UGAUG GCAUGCACUAUGC GCG AGAUCUUCCA
15183





3288
UGGAGUUCCU G UCUUC
5844
GAAGA UGAUG GCAUGCACUAUGC GCG AGGAACUCCA
15184





3302
UCCAGAAAGU G CAUUC
5845
GAAUG UGAUG GCAUGCACUAUGC GCG ACUUUCUGGA
15185





3324
ACCUGGCAGC G AGAAA
5846
UUUCU UGAUG GCAUGCACUAUGC GCG GCUGCCAGGU
15186





3343
UCUUUUAUCU G AGAAC
5847
GUUCU UGAUG GCAUGCACUAUGC GCG AGAUAAAAGA
15187





3357
ACAACGUGGU G AAGAU
5848
AUCUU UGAUG GCAUGCACUAUGC GCG ACCACGUUGU
15188





3365
GUGAAGAUUU G UGAUU
5849
AAUCA UGAUG GCAUGCACUAUGC GCG AAAUCUUCAC
15189





3367
GAAGAUUUGU G AUUUU
5850
AAAAU UGAUG GCAUGCACUAUGC GCG ACAAAUCUUC
15190





3379
UUUUGGCCUU G CCCGG
5851
CCGGG UGAUG GCAUGCACUAUGC GCG AAGGCCAAAA
15191





3403
UAAGAACCCC G AUUAU
5852
AUAAU UGAUG GCAUGCACUAUGC GCG GGGGUUCUUA
15192





3409
CCCCGAUUAU G UGAGA
5853
UCUCA UGAUG GCAUGCACUAUGC GCG AUAAUCGGGG
15193





3411
CCGAUUAUGU G AGAAA
5854
UUUCU UGAUG GCAUGCACUAUGC GCG ACAUAAUCGG
15194





3428
GGAGAUACUC G ACUUC
5855
GAAGU UGAUG GCAUGCACUAUGC GCG GAGUAUCUCC
15195





3438
GACUUCCUCU G AAAUG
5856
CAUUU UGAUG GCAUGCACUAUGC GCG AGAGGAAGUC
15196





3454
GAUGGCUCCC G AAUCU
5857
AGAUU UGAUG GCAUGCACUAUGC GCG GGGAGCCAUC
15197





3466
AUCUAUCUUU G ACAAA
5858
UUUGU UGAUG GCAUGCACUAUGC GCG AAAGAUAGAU
15198





3490
CACCAAGAGC G ACGUG
5859
CACGU UGAUG GCAUGCACUAUGC GCG GCUCUUGGUG
15199





3495
AGAGCGACGU G UGGUC
5860
GACCA UGAUG GCAUGCACUAUGC GCG ACGUGCCUCU
15200





3513
ACGGAGUAUU G CUGUG
5861
CACAG UGAUG GCAUGCACUAUGC GCG AAUACUCCGU
15201





3516
GAGUAUUGCU G UGGGA
5862
UCCCA UGAUG GCAUGCACUAUGC GCG AGCAAUACUC
15202





3568
ACAAAUGGAU G AGGAC
5863
GUCCU UGAUG GCAUGCACUAUGC GCG AUCCAUUUGU
15203





3578
GAGGACUUUU G CAGUC
5864
GACUG UGAUG GCAUGCACUAUGC GCG AAAAGUCCUC
15204





3584
UUUUGCAGUC G CCUGA
5865
UCAGG UGAUG GCAUGCACUAUGC GCG GACUGCAAAA
15205





3588
GCAGUCGCCU G AGGGA
5866
UCCCU UGAUG GCAUGCACUAUGC GCG AGGCGACUGC
15206





3600
GGGAAGGCAU G AGGAU
5867
AUCCU UGAUG GCAUGCACUAUGC GCG AUGCCUUCCC
15207





3606
GCAUCAGGAU G AGAGC
5868
GCUCU UGAUG GCAUGCACUAUGC GCG AUCCUCAUGC
15208





3616
GAGAGCUCCU G AGUAC
5869
CUACU UGAUG GCAUGCACUAUGC GCG AGGAGCUCUC
15209





3631
CUCUACUCCU G AAAUC
5870
GAUUU UGAUG GCAUGCACUAUGC GCG AGGAGUAGAG
15210





3648
AUCAGAUCAU G CUGGA
5871
UCCAG UGAUG GCAUGCACUAUGC GCG AUGAUCUGAU
15211





3656
AUGCUGGACU G CUGGC
5872
GCCAG UGAUG GCAUGCACUAUGC GCG AGUCCAGCAU
15212





3691
GCCAAGAUUU G CAGAA
5873
UUCUG UGAUG GCAUGCACUAUGC GCG AAAUCUUGGC
15213





3700
UGCAGAACUU G UGGAA
5874
UUCCA UGAUG GCAUGCACUAUGC GCG AAGUUCUGCA
15214





3715
AAAACUAGGU G AUUUG
5875
CAAAU UGAUG GCAUGCACUAUGC GCG ACCUAGUUUU
15215





3720
UAGGUGAUUU G CUUCA
5876
UGAAG UGAUG GCAUGCACUAUGC GCG AAAUCACCUA
15216





3733
UCAAGCAAAU G UACAA
5877
UUGUA UGAUG GCAUGCACUAUGC GCG AUUUGCUUGA
15217





3769
CCCAAUCAAU G CCAUA
5878
UAUGG UGAUG GCAUGCACUAUGC GCG AUUGAUUGGG
15218





3777
AUGCCAUACU G ACAGG
5879
CCUGU UGAUG GCAUGCACUAUGC GCG AGUAUGGCAU
15219





3811
CUCAACUCCU G CCUUC
5880
GAAGG UGAUG GCAUGCACUAUGC GCG AGGAGUUGAG
15220





3820
UGCCUUCUCU G AGGAC
5881
GUCCU UGAUG GCAUGCACUAUGC GCG AGAGAAGGCA
15221





3852
UUUCAGCUCC G AAGUU
5882
AACUU UGAUG GCAUGCACUAUGC GCG GGAGCUGAAA
15222





3874
AGGAAGCUCU G AUGAU
5883
AUCAU UGAUG GCAUGCACUAUGC GCG AGAGCUUCCU
15223





3877
AAGCUCUGAU G AUGUC
5884
GACAU UGAUG GCAUGCACUAUGC GCG AUCAGAGCUU
15224





3880
CUCUGAUGAU G UCAGA
5885
UCUGA UGAUG GCAUGCACUAUGC GCG AUCAUCAGAG
15225





3889
UGUCAGAUAU G UAAAU
5886
AUUUA UGAUG GCAUGCACUAUGC GCG AUAUCUGACA
15226





3895
AUAUGUAAAU G CUUUC
5887
GAAAG UGAUG GCAUGCACUAUGC GCG AUUUACAUAU
15227





3909
UCAAGUUCAU G AGCCU
5888
AGGCU UGAUG GCAUGCACUAUGC GCG AUGAACUUGA
15228





3934
CAAAACCUUU G AAGAA
5889
UUCUU UGAUG GCAUGCACUAUGC GCG AAAGGUUUUG
15229





3948
AACUUUUACC G AAUGC
5890
GCAUU UGAUG GCAUGCACUAUGC GCG GGUAAAAGUU
15230





3952
UUUACCGAAU G CCACC
5891
GGUGG UGAUG GCAUGCACUAUGC GCG AUUCGGUAAA
15231





3963
CCACCUCCAU G UUUGA
5892
UCAAA UGAUG GCAUGCACUAUGC GCG AUGGAGGUGG
15232





3967
CUCCAUGUUU G AUGAC
5893
GUCAU UGAUG GCAUGCACUAUGC GCG AAACAUGGAG
15233





3970
CAUGUUUGAU G ACUAC
5894
GUAGU UGAUG GCAUGCACUAUGC GCG AUCAAACAUG
15234





3982
CUACCAGGGC G ACAGC
5895
GCUGU UGAUG GCAUGCACUAUGC GCG GCCCUGGUAG
15235





3996
GCAGCACUCU G UUGGC
5896
GCCAA UGAUG GCAUGCACUAUGC GCG AGAGUGCUGC
15236





4011
CCUCUCCCAU G CUGAA
5897
UUCAG UGAUG GCAUGCACUAUGC GCG AUGGGAGAGG
15237





4014
CUCCCAUGCU G AAGCG
5898
CGCUU UGAUG GCAUGCACUAUGC GCG AGCAUGGGAG
15238





4019
AUGCUGAAGC G CUUCA
5899
UGAAG UGAUG GCAUGCACUAUGC GCG GCUUCAGCAU
15239





4033
CACCUGGACU G ACAGC
5900
GCUGU UGAUG GCAUGCACUAUGC GCG AGUCCAGGUG
15240





4053
CCAAGGCCUC G CUCAA
5901
UUGAG UGAUG GCAUGCACUAUGC GCG GAGGCCUUGG
15241





4063
GCUCAAGAUU G ACUUG
5902
CAAGU UGAUG GCAUGCACUAUGC GCG AAUCUUGAGC
15242





4068
AGAUUGACUU G AGAGU
5903
ACUCU UGAUG GCAUGCACUAUGC GCG AAGUCAAUCU
15243





4101
AGUCGGGGCU G UCUGA
5904
UCAGA UGAUG GCAUGCACUAUGC GCG AGCCCCGACU
15244





4105
GGGGCUGUCU G AUGUC
5905
GACAU UGAUG GCAUGCACUAUGC GCG AGACAGCCCC
15245





4108
GCUGUCUGAU G UCAGC
5906
GCUGA UGAUG GCAUGCACUAUGC GCG AUCAGACAGC
15246





4127
CCCAGUUUCU G CCAUU
5907
AAUGG UGAUG GCAUGCACUAUGC GCG AGAAACUGGG
15247





4139
CAUUCCAGCU G UGGGC
5908
GCCCA UGAUG GCAUGCACUAUGC GCG AGCUGGAAUG
15248





4153
GCACGUCAGC G AAGGC
5909
GCCUU UGAUG GCAUGCACUAUGC GCG GCUGACGUGC
15249





4163
GAAGGCAAGC G CAGGU
5910
ACCUG UGAUG GCAUGCACUAUGC GCG GCUUGCCUUC
15250





4177
GUUCACCUAC G ACCAC
5911
GUGGU UGAUG GCAUGCACUAUGC GCG GUAGGUGAAC
15251





4183
CUACGACCAC G CUGAG
5912
CUCAG UGAUG GCAUGCACUAUGC GCG GUGGUCGUAG
15252





4186
CGACCACGCU G AGCUG
5913
CAGCU UGAUG GCAUGCACUAUGC GCG AGCGUGGUCG
15253





4204
AAGGAAAAUC G CGUGC
5914
GCACG UGAUG GCAUGCACUAUGC GCG GAUUUUCCUU
15254





4208
AAAAUCGCGU G CUGCU
5915
AGCAG UGAUG GCAUGCACUAUGC GCG ACGCGAUUUU
15255





4211
AUCGCGUGCU G CUCCC
5916
GGGAG UGAUG GCAUGCACUAUGC GCG AGCACGCGAU
15256





4218
GCUGCUCCCC G CCCCC
5917
GGGGG UGAUG GCAUGCACUAUGC GCG GGGGAGCAGC
15257





4245
CGGUGGUCCU G UACUC
5918
GAGUA UGAUG GCAUGCACUAUGC GCG AGGACCACCG
15258





4272
UCUAGAGUUU G ACACG
5919
CGUGU UGAUG GCAUGCACUAUGC GCG AAACUCUAGA
15259





4277
AGUUUGACAC G AAGCC
5920
GGCUU UGAUG GCAUGCACUAUGC GCG GUGUCAAACU
15260





4301
AGAAGCACAU G UGUAU
5921
AUACA UGAUG GCAUGCACUAUGC GCG AUGUGCUUCU
15261





4303
AAGCACAUGU G UAUUU
5922
AAAUA UGAUG GCAUGCACUAUGC GCG ACAUGUGCUU
15262





4332
ACUAGCUUUU G CCAGU
5923
ACUGG UGAUG GCAUGCACUAUGC GCG AAAAGCUAGU
15263





4343
CCAGUAUUAU G CAUAU
5924
AUAUG UGAUG GCAUGCACUAUGC GCG AUAAUACUGG
15264





4386
GGAGCCAGCU G CUUUU
5925
AAAAG UGAUG GCAUGCACUAUGC GCG AGCUGGCUCC
15265





4393
GCUGCUUUUU G UGAUU
5926
AAUCA UGAUG GCAUGCACUAUGC GCG AAAAAGCAGC
15266





4395
UGCUUUUUGU G AUUUU
5927
AAAAU UGAUG GCAUGCACUAUGC GCG ACAAAAAGCA
15267





4410
UUUUAAUAGU G CUUUU
5928
AAAAG UGAUG GCAUGCACUAUGC GCG ACUAUUAAAA
15268





4423
UUUUUUUUUU G ACUAA
5929
UUAGU UGAUG GCAUGCACUAUGC GCG AAAAAAAAAA
15269





4436
UAACAAGAAU G UAACU
5930
AGUUA UGAUG GCAUGCACUAUGC GCG AUUCUUGUUA
15270





4459
GAGAAAUAGU G ACAAG
5931
CUUGU UGAUG GCAUGCACUAUGC GCG ACUAUUUCUC
15271





4466
AGUGACAAGU G AAGAA
5932
UUCUU UGAUG GCAUGCACUAUGC GCG ACUUGUCACU
15272





4479
GAACACUACU G CUAAA
5933
UUUAG UGAUG GCAUGCACUAUGC GCG AGUAGUGGUC
15273





4492
AAAUCCUCAU G UUACU
5934
AGUAA UGAUG GCAUGCACUAUGC GCG AUGAGGAUUU
15274





4502
GUUACUCAGU G UUAGA
5935
UCUAA UGAUG GCAUGCACUAUGC GCG ACUGAGUAAC
15275





4529
UAAACCCAAU G ACUUC
5936
GAAGU UGAUG GCAUGCACUAUGC GCG AUUGGGUUUA
15276





4538
UGACUUCCCU G CUCCA
5937
UGGAG UGAUG GCAUGCACUAUGC GCG AGGGAAGUCA
15277





4550
UCCAACCCCC G CCACC
5938
GGUGG UGAUG GCAUGCACUAUGC GCG GGGGGUUGGA
15278





4565
CUCAGGGCAC G CAGGA
5939
UCCUG UGAUG GCAUGCACUAUGC GCG GUGCCCUGAG
15279





4578
GGACCAGUUU G AUUGA
5940
UCAAU UGAUG GCAUGCACUAUGC GCG AAACUGGUCC
15280





4582
CAGUUUGAUU G AGGAG
5941
CUCCU UGAUG GCAUGCACUAUGC GCG AAUCAAACUG
15281





4590
UUGAGGAGCU G CACUG
5942
CAGUG UGAUG GCAUGCACUAUGC GCG AGCUCCUCAA
15282





4595
GAGCUGCACU G AUCAC
5943
GUGAU UGAUG GCAUGCACUAUGC GCG AGUGCAGCUC
15283





4606
AUCACCCAAU G CAUCA
5944
UGAUG UGAUG GCAUGCACUAUGC GCG AUUGGGUGAU
15284





4634
GGCCAGCCCU G CAGCC
5945
GGCUG UGAUG GCAUGCACUAUGC GCG AGGGCUGGCC
15285





4691
UGGCUGGCCU G AGCAA
5946
UUGCU UGAUG GCAUGCACUAUGC GCG AGGCCAGCCA
15286





4730
CCUAAGACAU G UGAGG
5947
CCUCA UGAUG GCAUGCACUAUGC GCG AUGUCUUAGG
15287





4732
UAAGACAUGU G AGGAG
5948
CUCCU UGAUG GCAUGCACUAUGC GCG ACAUGUCUUA
15288





4792
GAGAAGGCAU G AGAAA
5949
UUUCU UGAUG GCAUGCACUAUGC GCG AUGCCUUCUC
15289





4804
GAAAGAAUUU G AGACG
5950
CGUCU UGAUG GCAUGCACUAUGC GCG AAAUUCUUUC
15290





4809
AAUUUGAGAC G CACCA
5951
UGGUG UGAUG GCAUGCACUAUGC GCG GUCUCAAAUU
15291





4816
GACGCACCAU G UGGGC
5952
GCCCA UGAUG GCAUGCACUAUGC GCG AUGGUGCGUC
15292





4847
GCUCAGCAAU G CCAUU
5953
AAUGG UGAUG GCAUGCACUAUGC GCG AUUGCUGAGC
15293





4872
UCCCAGCUCU G ACCCU
5954
AGGGU UGAUG GCAUGCACUAUGC GCG AGAGCUGGGA
15294





4887
UUCUACAUUU G AGGGC
5955
GCCCU UGAUG GCAUGCACUAUGC GCG AAAUGUAGAA
15295





4916
GAUGGACAGC G AUGAG
5956
CUCAU UGAUG GCAUGCACUAUGC GCG GCUGUCCAUC
15296





4919
GGACAGCGAU G AGGGG
5957
CCCCU UGAUG GCAUGCACUAUGC GCG AUCGCUGUCC
15297





5018
GUGGUUCUAU G UCCAU
5958
AUGGA UGAUG GCAUGCACUAUGC GCG AUAGAACCAC
15298





5039
UUCGUGGCAU G UUUUG
5959
CAAAA UGAUG GCAUGCACUAUGC GCG AUGCCACGAA
15299





5044
GGCAUGUUUU G AUUUG
5960
CAAAU UGAUG GCAUGCACUAUGC GCG AAAACAUGCC
15300





5049
GUUUUGAUUU G UAGCA
5961
UGCUA UGAUG GCAUGCACUAUGC GCG AAAUCAAAAC
15301





5057
UUGUAGCACU G AGGGU
5962
ACCCU UGAUG GCAUGCACUAUGC GCG AGUGCUACAA
15302





5076
ACUCAACUCU G AGCCC
5963
GGCCU UGAUG GCAUGCACUAUGC GCG AGAGUUGAGU
15303





5107
CUAGUAAGAU G CACUG
5964
CAGUG UGAUG GCAUGCACUAUGC GCG AUCUUACUAG
15304





5112
AAGAUGCACU G AAAAC
5965
GUUUU UGAUG GCAUGCACUAUGC GCG AGUGCAUCUU
15305





5135
GAGUUAGGUU G UCUCC
5966
GGAGA UGAUG GCAUGCACUAUGC GCG AACCUAACUC
15306





5148
UCCAGGCCAU G AUGGC
5967
GCCAU UGAUG GCAUGCACUAUGC GCG AUGGCCUGGA
15307





5162
GCCUUACACU G AAAAU
5968
AUUUU UGAUG GCAUGCACUAUGC GCG AGUGUAAGGC
15308





5168
CACUGAAAAU G UCACA
5969
UGUGA UGAUG GCAUGCACUAUGC GCG AUUUUCAGUG
15309





5234
GUAUUAUUCU G UUUUG
5970
CAAAA UGAUG GCAUGCACUAUGC GCG AGAAUAAUAC
15310





5239
AUUCUGUUUU G CACAG
5971
CUGUG UGAUG GCAUGCACUAUGC GCG AAAACAGAAU
15311





5251
ACAGUUAGUU G UGAAA
5972
UUUCA UGAUG GCAUGCACUAUGC GCG AACUAACUGU
15312





5253
AGUUAGUUGU G AAAGA
5973
UCUUU UGAUG GCAUGCACUAUGC GCG ACAACUAACU
15313





5264
AAAGAAAGCU G AGAAG
5974
CUUCU UGAUG GCAUGCACUAUGC GCG AGCUUUCUUU
15314





5273
UGAGAAGAAU G AAAAU
5975
AUUUU UGAUG GCAUGCACUAUGC GCG AUUCUUCUCA
15315





5279
GAAUGAAAAU G CAGUC
5976
GACUG UGAUG GCAUGCACUAUGC GCG AUUUUCAUUC
15316





5287
AUGCAGUCCU G AGGAG
5977
CUCCU UGAUG GCAUGCACUAUGC GCG AGGACUGCAU
15317





5313
AUAUCAAAAC G AGGGC
5978
GCCCU UGAUG GCAUGCACUAUGC GCG GUUUUGAUAU
15318





5320
AACGAGGGCU G AUGGA
5979
UCCAU UGAUG GCAUGCACUAUGC GCG AGCCCUCGUU
15319





5469
ACACUAAUCU G AAAGG
5980
CCUUU UGAUG GCAUGCACUAUGC GCG AGAUUAGUGU
15320





5477
CUGAAAGGAU G UGGAA
5981
UUCCA UGAUG GCAUGCACUAUGC GCG AUCCUUUCAG
15321





5497
AUUAGCUGGC G CAUAU
5982
AUAUG UGAUG GCAUGCACUAUGC GCG GCCAGCUAAU
15322





5522
UAAGCUCCUU G AGUAA
5983
UUACU UGAUG GCAUGCACUAUGC GCG AAGGAGCUUA
15323





5539
AAGGUGGUAU G UAAUU
5984
AAUUA UGAUG GCAUGCACUAUGC GCG AUACCACCUU
15324





5548
UGUAAUUUAU G CAAGG
5985
CCUUG UGAUG GCAUGCACUAUGC GCG AUAAAUUACA
15325





5589
AUUAGUUAAU G AGCCA
5986
UGGCU UGAUG GCAUGCACUAUGC GCG AUUAACUAAU
15326





5623
AUUUUCAACU G CUUUG
5987
CAAAG UGAUG GCAUGCACUAUGC GCG AGUUGAAAAU
15327





5628
CAACUGCUUU G AAACU
5988
AGUUU UGAUG GCAUGCACUAUGC GCG AAAGCAGUUG
15328





5635
UUUGAAACUU G CCUGG
5989
CCAGG UGAUG GCAUGCACUAUGC GCG AAGUUUCAAA
15329





5646
CCUGGGGUCU G AGCAU
5990
AUGCU UGAUG GCAUGCACUAUGC GCG AGACCCCAGG
15330





5652
GUCUGAGCAU G AUGGG
5991
CCCAU UGAUG GCAUGCACUAUGC GCG AUGCUCAGAC
15331





5684
AGGAAAGGGC G CCUAC
5992
GUAGG UGAUG GCAUGCACUAUGC GCG GCCCUUUCCU
15332





5725
GCCUUGGAUC G CUAAG
5993
CUUAG UGAUG GCAUGCACUAUGC GCG GAUCCAAGGC
15333





5739
AGCUGGCUCU G UUUGA
5994
UCAAA UGAUG GCAUGCACUAUGC GCG AGAGCCAGCU
15334





5743
GGCUCUGUUU G AUGCU
5995
AGCAU UGAUG GCAUGCACUAUGC GCG AAACAGAGCC
15335





5746
UCUGUUUGAU G CUAUU
5996
AAUAG UGAUG GCAUGCACUAUGC GCG AUCAAACAGA
15336





5755
UGCUAUUUAU G CAAGU
5997
ACUUG UGAUG GCAUGCACUAUGC GCG AUAAAUAGCA
15337





5771
UAGGGUCUAU G UAUUU
5998
AAAUA UGAUG GCAUGCACUAUGC GCG AUAGACCCUA
15338





5782
UAUUUAGGAU G CGCCU
5999
AGGCG UGAUG GCAUGCACUAUGC GCG AUCCUAAAUA
15339





5784
UUUAGGAUGC G CCUAC
6000
GUAGG UGAUG GCAUGCACUAUGC GCG GCAUCCUAAA
15340





5825
GCCUUGGAUC G CUAAG
5993
CUUAG UGAUG GCAUGCACUAUGC GCG GAUCCAAGGC
15333





5839
AGCUGGCUCU G UUUGA
5994
UCAAA UGAUG GCAUGCACUAUGC GCG AGAGCCAGCU
15334





5843
GGCUCUGUUU G AUGCU
5995
AGCAU UGAUG GCAUGCACUAUGC GCG AAACAGAGCC
15335





5846
UCUGUUUGAU G CUAUU
5996
AAUAG UGAUG GCAUGCACUAUGC GCG AUCAAACAGA
15336





5855
UGCUAUUUAU G CAAGU
5997
ACUUG UGAUG GCAUGCACUAUGC GCG AUAAAUAGCA
15337





5871
UAGGGUCUAU G UAUUU
5998
AAAUA UGAUG GCAUGCACUAUGC GCG AUAGACCCUA
15338





5882
UAUUUAGGAU G UCUGC
6001
GCAGA UGAUG GCAUGCACUAUGC GCG AUCCUAAAUA
15341





5886
UAGGAUGUCU G CACCU
6002
AGGUG UGAUG GCAUGCACUAUGC GCG AGACAUCCUA
15342





5895
UGCACCUUCU G CAGCC
6003
GCCUG UGAUG GCAUGCACUAUGC GCG AGAAGGUGCA
15343





5931
ACAGUGGAUU G CUGCU
6004
AGCAG UGAUG GCAUGCACUAUGC GCG AAUCCACUGU
15344





5934
GUGGAUUGCU G CUUCU
6005
AGAAG UGAUG GCAUGCACUAUGC GCG AGCAAUCCAC
15345





5955
AGAAGAGUAU G CUUCC
6006
GGAAG UGAUG GCAUGCACUAUGC GCG AUACUCUUCU
15346





5971
UUUUAUCCAU G UAAUU
6007
AAUUA UGAUG GCAUGCACUAUGC GCG AUGGAUAAAA
15347





5982
UAAUUUAACU G UAGAA
6008
UUCUA UGAUG GCAUGCACUAUGC GCG AGUUAAAUUA
15348





5991
UGUAGAACCU G AGCUC
6009
GAGCU UGAUG GCAUGCACUAUGC GCG AGGUUCUACA
15349





6006
CUAAGUAACC G AAGAA
6010
UUCUU UGAUG GCAUGCACUAUGC GCG GGUUACUUAG
15350





6013
ACCGAAGAAU G UAUGC
6011
GCAUA UGAUG GCAUGCACUAUGC GCG AUUCUUCGGU
15351





6017
AAGAAUGUAU G CCUCU
6012
AGAGG UGAUG GCAUGCACUAUGC GCG AUACAUUCUU
15352





6023
GUAUGCCUCU G UUCUU
6013
AAGAA UGAUG GCAUGCACUAUGC GCG AGAGGCAUAC
15353





6031
CUGUUCUUAU G UGCCA
6014
UGGCA UGAUG GCAUGCACUAUGC GCG AUAAGAACAG
15354





6033
GUUCUUAUGU G CCACA
6015
UGUGG UGAUG GCAUGCACUAUGC GCG ACAUAAGAAC
15355





6044
CCACAUCCUU G UUUAA
6016
UUAAA UGAUG GCAUGCACUAUGC GCG AAGGAUGUGG
15356





6059
AAGGCUCUCU G UAUGA
6017
UCAUA UGAUG GCAUGCACUAUGC GCG AGAGAGCCUU
15357





6063
CUCUCUGUAU G AAGAG
6018
CUCUU UGAUG GCAUGCACUAUGC GCG AUACAGAGAG
15358





6098
AUUCCCUAGU G AGCCU
6019
AGGCU UGAUG GCAUGCACUAUGC GCG ACUAGGGAAU
15359





6127
AGCGGCUUUU G UGGAA
6020
UUCCA UGAUG GCAUGCACUAUGC GCG AAAAGCCGCU
15360





6230
ACAAAUCUUU G UUGUU
6021
AACAA UGAUG GCAUGCACUAUGC GCG AAAGAUUUCU
15361





6233
AAUCUUUGUU G UUCCU
6022
AGGAA UGAUG GCAUGCACUAUGC GCG AACAAAGAUU
15362





6254
UUACACAUAC G CAAAC
6023
GUUUG UGAUG GCAUGCACUAUGC GCG GUAUGUGUAA
15363





6265
CAAACCACCU G UGACA
6024
UGUCA UGAUG GCAUGCACUAUGC GCG AGGUGGUUUG
15364





6267
AACCACCUGU G ACAGC
6025
GCUGU UGAUG GCAUGCACUAUGC GCG ACAGGUGGUU
15265





6391
AGCAAAUAGU G AUAAC
6026
GUUAU UGAUG GCAUGCACUAUGC GCG ACUAUUUGCU
15366





6413
AACCUUAGCU G UUCAU
6027
AUGAA UGAUG GCAUGCACUAUGC GCG AGCUAAGGUU
15367





6419
AGCUGUUCAU G UCUUG
6028
CAAGA UGAUG GCAUGCACUAUGC GCG AUGAACAGCU
15368





6424
UUCAUGUCUU G AUUUC
6029
GAAAU UGAUG GCAUGCACUAUGC GCG AAGACAUGAA
15369





6504
CAUUAGAAUU G UUACU
6030
AGUAA UGAUG GCAUGCACUAUGC GCG AAUUCUAAUG
15370





6532
ACUCAGGUUU G UAGCA
6031
UGCUA UGAUG GCAUGCACUAUGC GCG AAACCUGAGU
15371





6543
UAGCAUACAU G AGUCC
6032
GGACU UGAUG GCAUGCACUAUGC GCG AUGUAUGCUA
15372





6588
GAGUCUUAAU G UAGAA
6033
UUCUA UGAUG GCAUGCACUAUGC GCG AUUAAGACUC
15373





6610
AUGGAGACUU G UAAUA
6034
UAUUA UGAUG GCAUGCACUAUGC GCG AAGUCUCCAU
15374





6618
UUGUAAUAAU G AGCUA
6035
UAGCU UGAUG GCAUGCACUAUGC GCG AUUAUUACAA
15375





6634
GUUACAAAGU G CUUGU
6036
ACAAG UGAUG GCAUGCACUAUGC GCG ACUUUGUAAC
15376





6638
CAAAGUGCUU G UUCAU
6037
AUGAA UGAUG GCAUGCACUAUGC GCG AAGCACUUUG
15377





6656
AAAUAGCACU G AAAAU
6038
AUUUU UGAUG GCAUGCACUAUGC GCG AGUGCUAUUU
15378





6663
ACUGAAAAUU G AAACA
6039
UGUUU UGAUG GCAUGCACUAUGC GCG AAUUUUCAGU
15379





6670
AUUGAAACAU G AAUUA
6040
UAAUU UGAUG GCAUGCACUAUGC GCG AUGUUUCAAU
15380





6679
UGAAUUAACU G AUAAU
6041
AUUAU UGAUG GCAUGCACUAUGC GCG AGUUAAUUCA
15381





6698
CCAAUCAUUU G CCAUU
6042
AAUGG UGAUG GCAUGCACUAUGC GCG AAAUGAUUGG
15382





6707
UGCCAUUUAU G ACAAA
6043
UUUGU UGAUG GCAUGCACUAUGC GCG AUAAAUGGCA
15383





6736
AACAAAGAAC G AGCAC
6044
GUGCU UGAUG GCAUGCACUAUGC GCG GUUCUUUGUU
15384





6759
CAGAGUUUCU G AGAUA
6045
UAUCU UGAUG GCAUGCACUAUGC GCG AGAAACUCUG
15385





6767
CUGAGAUAAU G UACGU
6046
ACGUA UGAUG GCAUGCACUAUGC GCG AUUAUCUCAG
15386





6798
GAAUGGGGCU G AAACC
6047
GGUUU UGAUG GCAUGCACUAUGC GCG AGCCCCAUUC
15387





6806
CUGAAACCAU G UGCAA
6048
UUGCA UGAUG GCAUGCACUAUGC GCG AUGGUUUCAG
15388





6808
GAAACCAUGU G CAAGU
6049
ACUUG UGAUG GCAUGCACUAUGC GCG ACAUGGUUUC
15389





6816
GUGCAAGUCU G UGUCU
6050
AGACA UGAUG GCAUGCACUAUGC GCG AGACUUGCAC
15390





6818
GCAAGUCUGU G UCUUG
6051
CAAGA UGAUG GCAUGCACUAUGC GCG ACAGACUUGC
15391





6823
UCUGUGUCUU G UCAGU
6052
ACUGA UGAUG GCAUGCACUAUGC GCG AAGACACAGA
15392





6838
UCCAAGAAGU G ACACC
6053
GGUGU UGAUG GCAUGCACUAUGC GCG ACUUCUUGGA
15393





6844
AAGUGACACC G AGAUG
6054
CAUCU UGAUG GCAUGCACUAUGC GCG GGUGUCACUU
15394





6849
ACACCGAGAU G UUAAU
6055
AUUAA UGAUG GCAUGCACUAUGC GCG AUCUCGGUGU
15395





6868
AGGGACCCGU G CCUUG
6056
CAAGG UGAUG GCAUGCACUAUGC GCG ACGGGUCCCU
15396





6873
CCCGUGCCUU G UUUCC
6057
GGAAA UGAUG GCAUGCACUAUGC GCG AAGGCACGGG
15397





6893
CCACAAGAAU G CAAAC
6058
GUUUG UGAUG GCAUGCACUAUGC GCG AUUCUUGUGG
15398





6914
ACAGAUACUC G CUAGC
6059
GCUAG UGAUG GCAUGCACUAUGC GCG GAGUAUCUGU
15399





6932
CAUUUAAAUU G AUUAA
6060
UUAAU UGAUG GCAUGCACUAUGC GCG AAUUUAAAUG
15400





6947
AAGGAGGAGU G CAUCU
6061
AGAUG UGAUG GCAUGCACUAUGC GCG ACUCCUCCUU
15401





6959
AUCUUUGGCC G ACAGU
6062
ACUGU UGAUG GCAUGCACUAUGC GCG GGCCAAAGAU
15402





6968
CGACAGUGGU G UAACU
6063
AGUUA UGAUG GCAUGCACUAUGC GCG ACCACUGUCG
15403





6974
UGGUGUAACU G UGUGU
6064
ACACA UGAUG GCAUGCACUAUGC GCG AGUUACACCA
15404





6976
GUGUAACUGU G UGUGU
6065
ACACA UGAUG GCAUGCACUAUGC GCG ACAGUUACAC
15405





6978
GUAACUGUGU G UGUGU
6066
ACACA UGAUG GCAUGCACUAUGC GCG ACACAGUUAC
15406





6980
AACUGUGUGU G UGUGU
6067
ACACA UGAUG GCAUGCACUAUGC GCG ACACACAGUU
15407





6982
CUGUGUGUGU G UGUGU
6068
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAG
15408





6984
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6986
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6988
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6990
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6992
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6994
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6996
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





6998
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7000
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7002
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7004
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7006
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7008
GUGUGUGUGU G UGUGU
6069
ACACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15409





7010
GUGUGUGUGU G UGUGG
6070
CCACA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15410





7012
GUGUGUGUGU G UGGGU
6071
ACCCA UGAUG GCAUGCACUAUGC GCG ACACACACAC
15411





7018
GUGUGUGGGU G UGGGU
6072
ACCCA UGAUG GCAUGCACUAUGC GCG ACCCACACAC
15412





7024
GGGUGUGGGU G UAUGU
6073
ACAUA UGAUG GCAUGCACUAUGC GCG ACCCACACCC
19413





7028
GUGGGUGUAU G UGUGU
6074
ACACA UGAUG GCAUGCACUAUGC GCG AUACACCCAC
15414





7030
GGGUGUAUGU G UGUUU
6075
AAACA UGAUG GCAUGCACUAUGC GCG ACAUACACCC
15415





7032
GUGUAUGUGU G UUUUG
6076
CAAAA UGAUG GCAUGCACUAUGC GCG ACACAUACAC
15416





7037
UGUGUGUUUU G UGCAU
6077
AUGCA UGAUG GCAUGCACUAUGC GCG AAAACACACA
15417





7039
UGUGUUUUGU G CAUAA
6078
UUAUG UGAUG GCAUGCACUAUGC GCG ACAAAACACA
15418





7099
AAGAAUAUAU G CUACA
6079
UGUAG UGAUG GCAUGCACUAUGC GCG AUAUAUUCUU
15419





7146
UUCUAGUCAU G AUGAA
6080
UUCAU UGAUG GCAUGCACUAUGC GCG AUGACUAGAA
15420





7149
UAGUCAUGAU G AAUGU
6081
ACAUU UGAUG GCAUGCACUAUGC GCG AUCAUGACUA
15421





7153
CAUGAUGAAU G UAUUU
6082
AAAUA UGAUG GCAUGCACUAUGC GCG AUUCAUCAUG
15422





7160
AAUGUAUUUU G UAUAC
6083
GUAUA UGAUG GCAUGCACUAUGC GCG AAAAUACAUU
15423





7210
AUUGGGAUUU G UAAUC
6084
GAUUA UGAUG GCAUGCACUAUGC GCG AAAUCCCAAU
15424





7230
CAACUUAAUU G AUAAA
6085
UUUAU UGAUG GCAUGCACUAUGC GCG AAUUAAGUUG
15425





7246
CUUGGCAACU G CUUUU
6086
AAAAG UGAUG GCAUGCACUAUGC GCG AGUUGCCAAG
15426





7254
CUGCUUUUAU G UUCUG
6087
CAGAA UGAUG GCAUGCACUAUGC GCG AUAAAAGCAG
15427





7259
UUUAUGUUCU G UCUCC
6088
GGAGA UGAUG GCAUGCACUAUGC GCG AGAACAUAAA
15428





7343
AUUUAUCCUU G UUUAC
6089
CUAAA UGAUG GCAUGCACUAUGC GCG AAGGAUAAAU
15429





7375
GAAAAACUUU G AAAUG
6090
CAUUU UGAUG GCAUGCACUAUGC GCG AAAGUUUUUC
15430





7394
UCAAAAAAUU G CUAAA
6091
UUUAG UGAUG GCAUGCACUAUGC GCG AAUUUUUUGA
15431





7422
AAAACUAAAU G UUAGU
6092
ACUAA UGAUG GCAUGCACUAUGC GCG AUUUAGUUUU
15432





7434
UAGUUUAGCU G AUUGU
6093
ACAAU UGAUG GCAUGCACUAUGC GCG AGCUAAACUA
15433





7438
UUAGCUGAUU G UAUGG
6094
CCAUA UGAUG GCAUGCACUAUGC GCG AAUCAGCUAA
15434





7451
UGGGGUUUUC G AACCU
6095
AGGUU UGAUG GCAUGCACUAUGC GCG GAAAACCCCA
15435





7467
UUCACUUUUU G UUUGU
6096
ACAAA UGAUG GCAUGCACUAUGC GCG AAAAAGUGAA
15436





7471
CUUUUUGUUU G UUUUA
6097
UAAAA UGAUG GCAUGCACUAUGC GCG AAACAAAAAG
15437





7491
UUUCACAACU G UGUAA
6098
UUACA UGAUG GCAUGCACUAUGC GCG AGUUGUGAAA
15438





7493
UCACAACUGU G UAAAU
6099
AUUUA UGAUG GCAUGCACUAUGC GCG ACAGUUGUGA
15439





7500
UGUGUAAAUU G CCAAU
6100
AUUGG UGAUG GCAUGCACUAUGC GCG AAUUUACACA
15440





7513
AAUAAUUCCU G UCCAU
6101
AUGGA UGAUG GCAUGCACUAUGC GCG AGGAAUUAUU
15441





7519
UCCUGUCCAU G AAAAU
6102
AUUUU UGAUG GCAUGCACUAUGC GCG AUGGACAGGA
15442





7525
CCAUGAAAAU G CAAAU
6103
AUUUG UGAUG GCAUGCACUAUGC GCG AUUUUCAUGG
15443





7539
AUUAUCCAGU G UAGAU
6104
AUCUA UGAUG GCAUGCACUAUGC GCG ACUGGAUAAU
15444





7551
AGAUAUAUUU G ACCAU
6105
AUGGU UGAUG GCAUGCACUAUGC GCG AAAUAUAUCU
15445





7582
GGCUAGUUUU G CCUUU
6106
AAAGG UGAUG GCAUGCACUAUGC GCG AAAACUAGCC
15446





7611
AUUUCAGCCU G AAUGU
6107
ACAUU UGAUG GCAUGCACUAUGC GCG AGGCUGAAAU
15447





7615
CAGCCUGAAU G UCUGC
6108
GCAGA UGAUG GCAUGCACUAUGC GCG AUUCAGGCUG
15448





7619
CUGAAUGUCU G CCUAU
6109
AUAGG UGAUG GCAUGCACUAUGC GCG AGACAUUCAG
15449





7634
UAUAUUCUCU G CUCUU
6110
AAGAG UGAUG GCAUGCACUAUGC GCG AGAGAAUAUA
15450





7641
UCUGCUCUUU G UAUUC
6111
GAAUA UGAUG GCAUGCACUAUGC GCG AAAGAGCAGA
15451





7653
AUUCUCCUUU G AACCC
6112
GGGUU UGAUG GCAUGCACUAUGC GCG AAAGGAGAAU
15452





7672
AAAACAUCCU G UGGCA
6113
UGCCA UGAUG GCAUGCACUAUGC GCG AGGAUGUUUU
15453










[0355]

19






TABLE XV










Human KDR NCH Ribozyme and Target Sequences















Seq ID

Seq ID



Pos
Target
No
Ribozyme Sequence
No.















11
CAAGGUGC U GCUGGCCG
6114
CGGCCAGC CUGAUGAGGCCGUUAGGCCGAA ICACCUUG
15454






14
GGUGCUGC U GGCCGUCG
6115
CGACGGCC CUGAUGAGGCCGUUAGGCCGAA ICAGCACC
15455





18
CUGCUGGC C GUCGCCCU
6116
AGGGCGAC CUGAUGAGGCCGUUAGGCCGAA ICCAGCAG
15456





24
GCCGUCGC C CUGUGGCU
6117
AGCCACAG CUGAUGAGGCCGUUAGGCCGAA ICGACGGC
15457





25
CCGUCGCC C UGUGGCUC
6118
GAGCCACA CUGAUGAGGCCGUUAGGCCGAA IGCGACGG
15458





26
CGUCGCCC U GUGGCUCU
6119
AGAGCCAC CUGAUGAGGCCGUUAGGCCGAA IGGCGACG
15459





32
CCUGUGGC U CUGCGUGG
6120
CCACGCAG CUGAUGAGGCCGUUAGGCCGAA ICCACAGG
15460





34
UGUGGCUC U GCGUGGAG
6121
CUCCACGC CUGAUGAGGCCGUUAGGCCGAA IAGCCACA
15461





45
GUGGAGAC C CGGGCCGC
6122
GCGGCCCG CUGAUGAGGCCGUUAGGCCGAA IUCUCCAC
15462





46
UGGAGACO C GGGCCGCC
6123
GGCGGCCC CUGAUGAGGCCGUUAGGCCGAA IGUCUCCA
15463





51
ACCCGGGC C GCCUCUGU
6124
ACAGAGGC CUGAUGAGGCCGUUAGGCCGAA ICCCGGGU
15464





54
CGGGCCGC C UCUGUGGG
6125
CCCACAGA CUGAUGAGGCCGUUAGGCCGAA ICGGCCCG
15465





55
GGGCCGCC U CUGUGGGU
6126
ACCCACAG CUGAUGAGGCCGUUAGGCCGAA IGCGGCCC
15466





57
GCCGCCUC U GUGGGUUU
6127
AAACCCAC CUGAUGAGGCCGUUAGGCCGAA IAGGCGGC
15467





68
GGGUUUGC C UAGUGUUU
6128
AAACACUA CUGAUGAGGCCGUUAGGCCGAA ICAAACCC
15468





69
GGUUUGCC U AGUGUUUC
6129
GAAACACU CUGAUGAGGCCGUUAGGCCGAA IGCAAACC
15469





78
AGUGUUUC U CUUGAUCU
6130
AGAUCAAG CUGAUGAGGCCGUUAGGCCGAA IAAACACU
15470





80
UGUUUCUC U UGAUCUGC
6131
GCAGAUCA CUGAUGAGGCCGUUAGGCCGAA IAGAAACA
15471





86
UCIUGAUC U GCCCAGGC
6132
GCCUGGGC CUGAUGAGGCCGUUAGGCCGAA IAUCAAGA
15472





89
UGAUCUGC C CAGUCUCA
6133
UGAGCCUG CUGAUGAGGCCGUUAGGCCGAA ICAGAUCA
15473





90
GAUCUGCC C AGGCUCAG
6134
CUGAGCCU CUGAUGAGGCCGUUAGGCCGAA IGCAGAUC
15474





91
AUCUGCCC A GGCUCAGC
6135
GCUGAGCC CUGAUGAGGCCGUUAGGCCGAA IGGCAGAU
15475





95
GCCCAGGC U CAGCAUAC
6136
GUAUGCUG CUGAUGAGGCCGUUAGGCCGAA ICCUGGGC
15476





97
CCAGGCUC A GCAUACAA
6137
UUGUAUGC CUGAUGAGGCCGUUAGGCCGAA IAGCCUGG
15477





100
GGCUCAGC A UACAAAAA
6138
UUUUUGUA CUGAUGAGGCCGUUAGGCCGAA ICUGAGCC
15478





104
CAGCAUAC A AAAAGACA
6139
UGUCUUUU CUGAUGAGGCCGUUAGGCCGAA IUAUGCUG
15479





112
AAAAAGAC A UACUUACA
6140
UGUAAGUA CUGAUGAGGCCGUUAGGCCGAA IUCUUUUU
15480





116
AGACAUAC U UACAAUUA
6141
UAAUUGUA CUGAUGAGGCCGUUAGGCCGAA IUAUGUCU
15481





120
AUACUUAC A AUUAAGGC
6142
GCCUUAAU CUGAUGAGGCCGUUAGGCCGAA IUAAGUAU
15482





129
AUUAAGGC U AAUACAAC
6143
GUUGUAUU CUGAUGAGGCCGUUAGGCCGAA ICCUUAAU
15483





135
GCUAAUAC A ACUCUUCA
6144
UGAAGAGU CUGAUGAGGCCGUUAGGCCGAA IUAUUAGC
15484





138
AAUACAAC U CUUCAAAU
6145
AUUUGAAG CUGAUGAGGCCGUUAGGCCGAA IUUGUAUU
15485





140
UACAACUC U UCAAAUUA
6146
UAAUUUGA CUGAUGAGGCCGUUAGGCCGAA IAGUUGUA
15486





143
AACUCUUC A AAUUACUU
6147
AAGUAAUU CUGAUGAGGCCGUUAGGCCGAA IAAGAGUU
15487





150
CAAAUUAC U UGCAGGGG
6148
CCCCUGCA CUGAUGAGGCCGUUAGGCCGAA IUAAUUUG
15488





154
UUACUUGC A GGGGACAG
6149
CUGUCCCC CUGAUGAGGCCGUUAGGCCGAA ICAAGUAA
15489





161
CAGGGGAC A GAGGGACU
6150
AGUCCCUC CUGAUGAGGCCGUUAGGCCGAA IUCCCCUG
15490





169
AGAGGGAC U UGGACUGG
6151
CCAGUCCA CUGAUGAGGCCGUUAGGCCGAA IUCCCUCU
15491





175
ACUUGGAC U GGCUUUGG
6152
CCAAAGCC CUGAUGAGGCCGUUAGGCCGAA IUCCAAGU
15492





179
GGACUGGC U JUGGCCCA
6153
UGGGCCAA CUGAUGAGGCCGUUAGGCCGAA ICCAGUCC
15493





185
GCUUUGGC C CAAUAAUC
6154
GAUUAUUG CUGAUGAGGCCGUUAGGCCGAA ICCAAAGC
15494





186
CUUUGGCC C AAUAAUCA
6155
UGAUUAUU CUGAUGAGGCCGUUAGGCCGAA IGCCAAAG
15495





187
UUUGGCCC A AUAAUCAG
6156
CUGAUUAU CUGAUGAGGCCGUUAGGCCGAA IGGCCAAA
15496





194
CAAUAAUC A GAGUGGCA
6157
UGCCACUC CUGAUGAGGCCGUUAGGCCGAA IAUUAUUG
15497





202
AGAGUGGC A GUGAGCAA
6158
UUGCUCAC CUGAUGAGGCCGUUAGGCCGAA ICCACUCU
15498





209
CAGUGAGC A AAGGGUGG
6159
CCACCCUU CUGAUGAGGCCGUUAGGCCGAA ICUCACUG
15499





225
GAGGUGAC U GAGUGCAG
6160
CUGCACUC CUGAUGAGGCCGUUAGGCCGAA IUCACCUC
15500





232
CUGAGUGC A GCGAUGGC
6161
GCCAUCGC CUGAUGAGGCCGUUAGGCCGAA ICACUCAG
15501





241
GCGAUGGC C UCUUCUGU
6162
ACAGAAGA CUGAUGAGGCCGUUAGGCCGAA ICCAUCGC
15502





242
CGAUGGCC U CUUCUGUA
6163
UACAGAAG CUGAUGAGGCCGUUAGGCCGAA IGCCAUCG
15503





244
AUGGCCUC U UCUGUAAG
6164
CUUACAGA CUGAUGAGGCCGUUAGGCCGAA IAGGCCAU
15504





247
GCCUCUUC U GUAAGACA
6165
UGUCUUAC CUGAUGAGGCCGUUAGGCCGAA IAAGAGGC
15505





255
UGUAAGAC A CUCACAAU
6166
AUUGUGAG CUGAUGAGGCCGUUAGGCCGAA IUCUUACA
15506





257
UAAGACAC U CACAAUUC
6167
GAAUUGUG CUGAUGAGGCCGUUAGGCCGAA IUGUCUUA
15507





259
AGACACUC A CAAUUCCA
6168
UGGAAUUG CUGAUGAGGCCGUUAGGCCGAA IAGUGUCU
15508





261
ACACUCAC A AUUCCAAA
6169
UUUGGAAU CUGAUGAGGCCGUUAGGCCGAA IUGAGUGU
15509





266
CACAAUUC C AAAAGUGA
6170
UCACUUEU CUGAUGAGGCCGUUAGGCCGAA IAAUUGUG
15510





267
ACAAUUCC A AAAGUGAU
6171
AUCACUUU CUGAUGAGGCCGUUAGGCCGAA IGAAUUGU
15511





286
GAAAUGAC A CUGGAGCC
6172
GGCUCCAG CUGAUGAGGCCGUUAGGCCGAA IUCAUUUC
15512





288
AAUGACAC U GGAGCCUA
6173
UAGGCUCC CUGAUGAGGCCGUUAGGCCGAA IUGUCAUU
15513





294
ACUGGAGC C UACAAGUG
6174
CACUUGUA CUGAUGAGGCCGUUAGGCCGAA ICUCCAGU
15514





295
CUGGAGCC U ACAAGUGC
6175
GCACUUGU CUGAUGAGGCCGUUAGGCCGAA IGCUCCAG
15515





298
GAGCCUAC A AGUGCUUC
6176
GAAGCACU CUGAUGAGGCCGUUAGGCCGAA IUAGGCUC
15516





304
ACAAGUGC U UCUACCGG
6177
CCGGUAGA CUGAUGAGGCCGUUAGGCCGAA ICACUUGU
15517





307
AGUGCUUC U ACCGGGAA
6178
UUCCCGGU CUGAUGAGGCCGUUAGGCCGAA IAAGCACU
15518





310
GCUUCUAC C GGGAAACU
6179
AGUUUCCC CUGAUGAGGCCGUUAGGCCGAA IUAGAAGC
15519





318
CGGGAAAC U GACUUGGC
6180
GCCAAGUC CUGAUGAGGCCGUUAGGCCGAA IUUUCCCG
15520





322
AAACUGAC U UGGCCUCG
6181
CGAGGCCA CUGAUGAGGCCGUUAGGCCGAA IUCAGUUU
15521





327
GACUUGGC C UCGGUCAU
6182
AUGACCGA CUGAUGAGGCCGUUAGGCCGAA ICCAAGUC
15522





328
ACUUGGCC U CGGUCAUU
6183
AAUGACCG CUGAUGAGGCCGUUAGGCCGAA IGCCAAGU
15523





334
CCUCGGUC A UUUAUGUC
6184
GACAUAAA CUGAUGAGGCCGUUAGGCCGAA IACCGAGG
15524





343
UUUAUGUC U AUGUUCAA
6185
UUGAACAU CUGAUGAGGCCGUUAGGCCGAA IACAUAAA
15525





350
CUAUGUUC A AGAUUACA
6186
UGUAAUCU CUGAUGAGGCCGUUAGGCCGAA IAACAUAG
15526





358
AAGAUUAC A GAUCUCCA
6187
UGGAGAUC CUGAUGAGGCCGUUAGGCCGAA IUAAUCUU
15527





363
UACAGAUC U CCAUUUAU
6188
AUAAAUGG CUGAUGAGGCCGUUAGGCCGAA IAUCUGUA
15528





365
CAGAUCUC C AUUUAUUG
6189
CAAUAAAU CUGAUGAGGCCGUUAGGCCGAA IAGAUCUG
15529





366
AGAUCUCC A UUUAUUGC
6190
GCAAUAAA CUGAUGAGGCCGUUAGGCCGAA IGAGAUCU
15530





375
UUUAUUGC U UCUGUUAG
6191
CUAACAGA CUGAUGAGGCCGUUAGGCCGAA ICAAUAAA
15531





378
AUUGCUUC U GUUAGUGA
6192
UCACUAAC CUGAUGAGGCCGUUAGGCCGAA IAAGCAAU
15532





388
UUAGUGAC C AACAUGGA
6193
UCCAUGUU CUGAUGAGGCCGUUAGGCCGAA IUCACUAA
15533





389
UAGUGACC A ACAUGGAG
6194
CUCCAUGU CUGAUGAGGCCGUUAGGCCGAA IGUCACUA
15534





392
UGACCAAC A UGGAGUCG
6195
CGACUCCA CUGAUGAGGCCGUUAGGCCGAA IUUGGUCA
15535





406
UCGUGUAC A UUACUGAG
6196
CUCAGUAA CUGAUGAGGCCGUUAGGCCGAA IUACACGA
15536





411
UACAUUAC U GAGAACAA
6197
UUGUUCUC CUGAUGAGGCCGUUAGGCCGAA IUAAUGUA
15537





418
CUGAGAAC A AAAACAAA
6198
UTUGUUUU CUGAUGAGGCCGUUAGGCCGAA IUUCUCAG
15538





424
ACAAAAAC A AAACUGUG
6199
CACAGUUU CUGAUGAGGCCGUUAGGCCGAA IUUUUUGU
15539





429
AACAAAAC U GUGGUGAU
6200
AUCACCAC CUGAUGAGGCCGUUAGGCCGAA IUUUUGUU
15540





440
GGUGAUUC C AUGUCUCG
6201
CGAGACAU CUGAUGAGGCCGUUAGGCCGAA IAAUCACC
15541





441
GUGAUUCC A UGUCUCGG
6202
CCGAGACA CUGAUGAGGCCGUUAGGCCGAA IGAAUCAC
15542





446
UCCAUGUC U CGGGUCCA
6203
UGGACCCG CUGAUGAGGCCGUUAGGCCGAA IACAUGGA
15543





453
CUCGGGUC C AUUUCAAA
6204
UUUGAAAU CUGAUGAGGCCGUUAGGCCGAA IACCCGAG
15544





454
UCGGGUCC A UUUCAAAU
6205
AUUUGAAA CUGAUGAGGCCGUUAGGCCGAA IGACCCGA
15545





459
UCCAUUUC A AAUCUCAA
6206
UUGAGAUU CUGAUGAGGCCGUUAGGCCGAA IAAAUGGA
15546





464
UUCAAAUC U CAACGUGU
6207
ACACGUUG CUGAUGAGGCCGUUAGGCCGAA IAUUUGAA
15547





466
CAAAUCUC A ACGUGUCA
6208
UGACACGU CUGAUGAGGCCGUUAGGCCGAA IAGAUUUG
15548





474
AACGUGUC A CUUUGUGC
6209
GCACAAAG CUGAUGAGGCCGUUAGGCCGAA IACACGUU
15549





476
CGUGUCAC U UUGUGCAA
6210
UUGCACAA CUGAUGAGGCCGUUAGGCCGAA IUGACACG
15550





483
CUUUGUGC A AGAUACCC
6211
GGGUAUCU CUGAUGAGGCCGUUAGGCCGAA ICACAAAG
15551





490
CAAGAUAC C CAGAAAAG
6212
CUUUUCUG CUGAUGAGGCCGUUAGGCCGAA ICAUCCUG
15552





491
AAGAUACC C AGAAAAGA
6213
UCUUUUCU CUGAUGAGGCCGUUAGGCCGAA IGUAUCUU
15553





492
AGAUACCC A GAAAAGAG
6214
CUCUUUUC CUGAUGAGGCCGUUAGGCCGAA IGGUAUCU
15554





509
AUUUGUUC C UGAUGGUA
6215
UACCAUCA CUGAUGAGGCCGUUAGGCCGAA IAACAAAU
15555





510
UUUGUUCC U GAUGGUAA
6216
UUACCAUC CUGAUGAGGCCGUUAGGCCGAA IGAACAAA
15556





520
AUGGUAAC A GAAUUUCC
6217
GGAAAUUC CUGAUGAGGCCGUUAGGCCGAA IUUACCAU
15557





528
AGAAUUUC C UGGGACAG
6218
CUGUCCCA CUGAUGAGGCCGUUAGGCCGAA IAAAUUCU
15558





529
GAAUUUCC U GGGACAGC
6219
GCUGUCCC CUGAUGAGGCCGUUAGGCCGAA IGAAAUUC
15559





535
CCUGGGAC A GCAAGAAG
6220
CUUCUUGC CUGAUGAGGCCGUUAGGCCGAA IUCCCAGG
15560





538
GGGACAGC A AGAAGGGC
6221
GCCCUUCU CUGAUGAGGCCGUUAGGCCGAA ICUGUCCC
15561





547
AGAAGGGC U UUACUAUU
6222
AAUAGUAA CUGAUGAGGCCGUUAGGCCGAA ICCCUUCU
15562





552
GGCUUUAC U AUUCCCAG
6223
CUGGGAAU CUGAUGAGGCCGUUAGGCCGAA IUAAAGCC
15563





557
UACUAUUC C CAGCUACA
6224
UGUAGCUG CUGAUGAGGCCGUUAGGCCGAA IAAUAGUA
15564





558
ACUAUUCC C AGCUACAU
6225
AUGUAGCU CUGAUGAGGCCGUUAGGCCGAA IGAAUAGU
15565





559
CUAUUCCC A GCUACAUG
6226
CAUGUAGC CUGAUGAGGCCGUUAGGCCGAA IGGAAUAG
15566





562
UUCCCAGC U ACAUGAUC
6227
GAUCAUGU CUGAUGAGGCCGUUAGGCCGAA ICUGGGAA
15567





565
CCAGCUAC A UGAUCAGC
6228
GCUGAUCA CUGAUGAGGCCGUUAGGCCGAA IUAGCUGG
15568





571
ACAUGAUC A GCUAUGCU
6229
AGCAUAGC CUGAUGAGGCCGUUAGGCCGAA IAUCAUGU
15569





574
UGAUCAGC U AUGCUGGC
6230
GCCAGCAU CUGAUGAGGCCGUUAGGCCGAA ICUGAUCA
15570





579
AGCUAUGC U GGCAUGGU
6231
ACCAUGCC CUGAUGAGGCCGUUAGGCCGAA ICAUAGCU
15571





583
AUGCUGGC A UGGUCUUC
6232
GAAGACCA CUGAUGAGGCCGUUAGGCCGAA ICCAGCAU
15572





589
GCAUGGUC U UCUGUGAA
6233
UUCACAGA CUGAUGAGGCCGUUAGGCCGAA IACCAUGC
15573





592
UGGUCUUC U GUGAAGCA
6234
UGCUUCAC CUGAUGAGGCCGUUAGGCCGAA IAAGACCA
15574





600
UGUGAAGC A AAAAUUAA
6235
UUAAUUUU CUGAUGAGGCCGUUAGGCCGAA ICUUCACA
15575





622
AAAGUUAC C AGUCUAUU
6236
AAUAGACU CUGAUGAGGCCGUUAGGCCGAA IUAACUUU
15576





623
AAGUUACC A GUCUAUUA
6237
UAAUAGAC CUGAUGAGGCCGUUAGGCCGAA IGUAACUU
15577





627
UACCAGUC U AUUAUGUA
6238
UACAUAAU CUGAUGAGGCCGUUAGGCCGAA IACUGGUA
15578





637
UUAUGUAC A UAGUUGUC
6239
GACAACUA CUGAUGAGGCCGUUAGGCCGAA IUACAUAA
15579





677
UGUGGUUC U GAGUCCGU
6240
ACGGACUC CUGAUGAGGCCGUUAGGCCGAA IAACCACA
15580





683
UCUGAGUC C GUCUCAUG
6241
CAUGAGAC CUGAUGAGGCCGUUAGGCCGAA IACUCAGA
15581





687
AGUCCGUC U CAUGGAAU
6242
AUUCCAUG CUGAUGAGGCCGUUAGGCCGAA IACGGACU
15582





689
UCCGUCUC A UGGAAUUG
6243
CAAUUCCA CUGAUGAGGCCGUUAGGCCGAA IAGACGGA
15583





701
AAUUGAAC U AUCUGUUG
6244
CAACAGAU CUGAUGAGGCCGUUAGGCCGAA IUUCAAUU
15584





705
GAACUAUC U GUUGGAGA
6245
UCUCCAAC CUGAUGAGGCCGUUAGGCCGAA IAUAGUUC
15585





719
AGAAAAGC U UGUCUUAA
6246
UUAAGACA CUGAUGAGGCCGUUAGGCCGAA ICUUUUCU
15586





724
AGCUUGUC U UAAAUUGU
6247
ACAAUUUA CUGAUGAGGCCGUUAGGCCGAA IACAAGCU
15587





735
AAUUGUAC A GCAAGAAC
6248
GUUCUUGC CUGAUGAGGCCGUUAGGCCGAA IUACAAUU
15588





738
UGUACAGC A AGAACUGA
6249
UCAGUUCU CUGAUGAGGCCGUUAGGCCGAA ICUGUACA
15589





744
GCAAGAAC U GAACUAAA
6250
UUUAGUUC CUGAUGAGGCCGUUAGGCCGAA IUUCUUGC
15590





749
AACUGAAC U AAAUGUGG
6251
CCACAUUU CUGAUGAGGCCGUUAGGCCGAA IUUCAGUU
15591





766
GGAUUGAC U UCAACUGG
6252
CCAGUUGA CUGAUGAGGCCGUUAGGCCGAA IUCAAUCC
15592





769
UUGACUUC A ACUGGGAA
6253
UUCCCAGU CUGAUGAGGCCGUUAGGCCGAA IAAGUCAA
15593





772
ACUUCAAC U GGGAAUAC
6254
GUAUUCCC CUGAUGAGGCCGUUAGGCCGAA IUUGAAGU
15594





781
GGGAAUAC C CUUCUUCG
6255
CGAAGAAG CUGAUGAGGCCGUUAGGCCGAA IUAUUCCC
15595





782
GGAAUACC C UUCUUCGA
6256
UCGAAGAA CUGAUGAGGCCGUUAGGCCGAA IGUAUUCC
15596





783
GAAUACCC U UCUUCGAA
6257
UUCGAAGA CUGAUGAGGCCGUUAGGCCGAA IGGUAUUC
15597





786
UACCCUUC U UCGAAGCA
6258
UGCUUCGA CUGAUGAGGCCGUUAGGCCGAA IAAGGGUA
15598





794
UUCGAAGC A UCAGCAUA
6259
UAUGCUGA CUGAUGAGGCCGUUAGGCCGAA ICUUCGAA
15599





797
GAAGCAUC A GCAUAAGA
6260
UCUUAUGC CUGAUGAGGCCGUUAGGCCGAA IAUGCUUC
15600





800
GCAUCAGC A UAAGAAAC
6261
GUUUCUUA CUGAUGAGGCCGUUAGGCCGAA ICUGAUGC
15601





809
UAAGAAAC U UGUAAACC
6262
GGUUUACA CUGAUGAGGCCGUUAGGCCGAA IUUUCUUA
15602





817
UUGUAAAC C CAGACCUA
6263
UAGGUCUC CUGAUGAGGCCGUUAGGCCGAA IUUUACAA
15603





823
ACCGAGAC C UAAAAACC
6264
GGUUUUUA CUGAUGAGGCCGUUAGGCCGAA IUCUCGGU
15604





824
CCGAGACC U AAAAACCC
6265
GGGUUUUU CUGAUGAGGCCGUUAGGCCGAA IGUCUCGG
15605





831
CUAAAAAC C CAGUCUGG
6266
CCAGACUG CUGAUGAGGCCGUUAGGCCGAA IUUUUUAG
15606





832
UAAAAACC C AGUCUGGG
6267
CCCAGACU CUGAUGAGGCCGUUAGGCCGAA IGUUUUUA
15607





833
AAAAACCC A GUCUGGGA
6268
UCCCAGAC CUGAUGAGGCCGUUAGGCCGAA IGGUUUUU
15608





837
ACCCAGUC U GGGAGUGA
6269
UCACUCCC CUGAUGAGGCCGUUAGGCCGAA IACUGGGU
15609





865
UUUUGAGC A CCUUAACU
6270
AGUUAAGG CUGAUGAGGCCGUUAGGCCGAA ICUCAAAA
15610





867
UUGAGCAC C UUAACUAU
6271
AUAGUUAA CUGAUGAGGCCGUUAGGCCGAA IUGCUCAA
15611





868
UGAGCACC U UAACUAUA
6272
UAUAGUUA CUGAUGAGGCCGUUAGGCCGAA IGUGCUCA
15612





873
ACCUUAAC U AUAGAUGG
6273
CCAUCUAU CUGAUGAGGCCGUUAGGCCGAA IUUAAGGU
15613





888
GGUGUAAC C CGGAGUGA
6274
UCACUCCG CUGAUGAGGCCGUUAGGCCGAA IUUACACC
15614





889
GUGUAACC C CGAGUGAC
6275
GUCACUCC CUGAUGAGGCCGUUAGGCCGAA IGUUACAC
15615





898
GGAGUGAC C AAGGAUUG
6276
CAAUCCUU CUGAUGAGGCCGUUAGGCCGAA IUCACUCC
15616





899
GAGUGACC A AGGAUUGU
6277
ACAAUCCU CUGAUGAGGCCGUUAGGCCGAA ICUCACUC
15617





910
GAUUGUAC A CCUGUGCA
6278
UGCACAGG CUGAUGAGGCCGUUAGGCCGAA IUACAAUC
15618





912
UUGUACAC C UGUGCAGC
6279
GCUGCACA CUGAUGAGGCCGUUAGGCCGAA IUGUACAA
15619





913
UGUACACC U GUGCAGCA
6280
UGCUGCAC CUGAUCAGGCCGUUAGGCCGAA IGUGUACA
15620





918
ACCUGUGC A GCAUCCAG
6281
CUGGAUGC CUGAUGAGGCCGUUAGGCCGAA ICACAGGU
15621





921
UGUGCAGC A UCCAGUGG
6282
CCACUGGA CUGAUGAGGCCGUUAGGCCGAA ICUGCACA
15622





924
GCAGCAUC C AGUGGGCU
6283
AGCCCACU CUGAUGAGGCCGUUAGGCCGAA IAUGCUGC
15623





925
CAGCAUCC A GUGGGCUG
6284
CAGCCCAC CUGAUGAGGCCGUUAGGCCGAA IGAUGCUG
15624





932
CAGUGGGC U GAUGACCA
6285
UGGUCAUC CUGAUGAGGCCGUUAGGCCGAA ICCCACUG
15625





939
CUGAUGAC C AAGAAGAA
6286
UUCUUCUU CUGAUGAGGCCGUUAGGCCGAA IUCAUCAG
15626





940
UGAUGACC A AGAAGAAC
6287
GUUCUUCU CUGAUGAGGCCGUUAGGCCGAA IGUCAUCA
15627





949
AGAAGAAC A GCACAUUU
6288
AAAUGUGC CUGAUGAGGCCGUUAGGCCGAA IUUCUUCU
15628





952
AGAACAGC A CAUUUGUC
6289
GACAAAUG CUGAUGAGGCCGUUAGGCCGAA ICUGUUCU
15629





954
AACAGCAC A UUUGUCAG
6290
CUGACAAA CUGAUGAGGCCGUUAGGCCGAA IUGCUGUU
15630





961
CAUUUGUC A GGGUCCAU
6291
AUGGACCC CUGAUGAGGCCGUUAGGCCGAA IACAAAUG
15631





967
UCAGGGUC C AUGAAAAA
6292
UUUUUCAU CUGAUGAGGCCGUUAGGCCGAA IACCCUGA
15632





968
CAGGGUCC A UGAAAAAC
6293
GUUUUUCA CUGAUGAGGCCGUUAGGCCGAA IGACCCUG
15633





977
UGAAAAAC C UUUUGUUG
6294
CAACAAAA CUGAUGAGGCCGUUAGGCCGAA IUUUUUCA
15634





978
GAAAAACC U UUUGUUGC
6295
GCAACAAA CUGAUGAGGCCGUUAGGCCGAA IGUUUUUC
15635





987
UUUGUUGC U UUUGGAAG
6296
CUUCCAAA CUGAUGAGGCCGUUAGGCCGAA ICAACAAA
15636





1000
GAAGUGGC A UGGAAUCU
6297
AGAUUCCA CUGAUGAGGCCGUUAGGCCGAA ICCACUUC
15637





1008
AUGGAAUC U CUGGUGGA
6298
UCCACCAG CUGAUGAGGCCGUUAGGCCGAA IAUUCCAU
15638





1010
GGAAUCUC U GGUGGAAG
6299
CUUCCACC CUGAUGAGGCCGUUAGGCCGAA IAGAUUCC
15639





1020
GUGGAAGC C ACGGUGGG
6300
CCCACCGU CUGAUGAGGCCGUUAGGCCGAA ICUUCCAC
15640





1021
UGGAAGCC A CGGUGGGG
6301
CCCCACCG CUGAUGAGGCCGUUAGGCCGAA IGCUUCCA
15641





1039
AGCGUGUC A GAAUCCCU
6302
AGGGAUUC CUGAUGAGGCCGUUAGGCCGAA IACACGCU
15642





1045
UCAGAAUC C CUGCGAAG
6303
CUUCGCAG CUGAUGAGGCCGUUAGGCCGAA IAUUCUGA
15643





1046
CAGAAUCC C UGCGAAGU
6304
ACUUCGCA CUGAUGAGGCCGUUAGGCCGAA IGAUUCUG
15644





1047
AGAAUCCC U GCGAAGUA
6305
UACUUCGC CUGAUGAGGCCGUUAGGCCGAA IGGAUUCU
15645





1057
CGAAGUAC C UUGGUUAC
6306
GUAACCAA CUGAUGAGGCCGUUAGGCCGAA IUACUUCG
15646





1058
GAAGUACC U UGGUUACC
6307
GGUAACCA CUGAUGAGGCCGUUAGGCCGAA IGUACUUC
15647





1066
UUGGUUAC C CACCCCCA
6308
UGGGGGUG CUGAUGAGGCCGUUAGGCCGAA IUAACCAA
15648





1067
UGGUUACC C ACCCCCAG
6309
CUGGGGGU CUGAUGAGGCCGUUAGGCCGAA IGUAACCA
15649





1068
GGUUACCC A CCCCCAGA
6310
UCUGGGGG CUGAUGAGGCCGUUAGGCCGAA IGGUAACC
15650





1070
UUACCCAC C CCCAGAAA
6311
UUUCUGGG CUGAUGAGGCCGUUAGGCCGAA IUGGGUAA
15651





1071
UACCCACC C CCAGAAAU
6312
AUUUCUGG CUGAUGAGGCCGUUAGGCCGAA IGUGGGUA
15652





1072
ACCCACCC C CAGAAAUA
6313
UAUUUCUG CUGAUGAGGCCGUUAGGCCGAA IGGUGGGU
15653





1073
CCCACCCC C AGAAAUAA
6314
UUAUUUCU CUGAUGAGGCCGUUAGGCCGAA IGGGUGGG
15654





1074
CCACCCCC A GAAAUAAA
6315
UUUAUUUC CUGAUGAGGCCGUUAGGCCGAA IGGGGUGG
15655





1103
UGGAAUAC C CCUUGAGU
6316
ACUCAAGG CUGAUGAGGCCGUUAGGCCGAA IUAUUCCA
15656





1104
GGAAUACC C CUUGAGUC
6317
GACUCAAG CUGAUGAGGCCGUUAGGCCGAA IGUAUUCC
15657





1105
GAAUACCC C UUGAGUCC
6318
GGACUCAA CUGAUGAGGCCGUUAGGCCGAA IGGUAUUC
15658





1106
AAUACCCC U UGAGUCCA
6319
UGGACUCA CUGAUGAGGCCGUUAGGCCGAA IGGGUAUU
15659





1113
CUUGAGUC C AAUCACAC
6320
GUGUGAUU CUGAUGAGGCCGUUAGGCCGAA IACUCAAG
15660





1114
UUGAGUCC A AUCACACA
6321
UGUGUGAU CUGAUGAGGCCGUUAGGCCGAA IGACUCAA
15661





1118
GUCCAAUC A CACAAUUA
6322
UAAUUGUG CUGAUGAGGCCGUUAGGCCGAA IAUUGGAC
15662





1120
CCAAUCAC A CAAUUAAA
6323
UUUAAUUG CUGAUGAGGCCGUUAGGCCGAA IUGAUUGG
15663





1122
AAUCACAC A AUUAAAGC
6324
GCUUUAAU CUGAUGAGGCCGUUAGGCCGAA IUGUGAUU
15664





1136
AGCGGGGC A UGUACUGA
6325
UCAGUACA CUGAUGAGGCCGUUAGGCCGAA ICCCCGCU
15665





1142
GCAUGUAC U GACGAUUA
6326
UAAUCGUC CUGAUGAGGCCGUUAGGCCGAA IUACAUGC
15666





1171
AAAGAGAC A CAGGAAAU
6327
AUUUCCUG CUGAUGAGGCCGUUAGGCCGAA IUCUCUUU
15667





1173
AGAGACAC A GGAAAUUA
6328
UAAUUUCC CUGAUGAGGCCGUUAGGCCGAA IUGUCUCU
15668





1183
GAAAUUAC A CUGUCAUC
6329
GAUGACAG CUGAUGAGGCCGUUAGGCCGAA IUAAUUUC
15669





1185
AAUUACAC U GUCAUCCU
6330
AGGAUGAC CUGAUGAGGCCGUUAGGCCGAA IUGUAAUU
15670





1189
ACACUGUC A UCCUUACC
6331
GGUAAGGA CUGAUGAGGCCGUUAGGCCGAA IACAGUGU
15671





1192
CUGUCAUC C UUACCAAU
6332
AUUGGUAA CUGAUGAGGCCGUUAGGCCGAA IAUGACAG
15672





1193
UGUCAUCC U UACCAAUC
6333
GAUUGGUA CUGAUGAGGCCGUUAGGCCGAA IGAUGACA
15673





1197
AUCCUUAC C AAUCCCAU
6334
AUGGGAUU CUGAUGAGGCCGUUAGGCCGAA IUAAGGAU
15674





1198
UCCUUACC A AUCCCAUU
6335
AAUGGGAU CUGAUGAGGCCGUUAGGCCGAA IGUAAGGA
15675





1202
UACCAAUC C CAUUUCAA
6336
UUGAAAUG CUGAUGAGGCCGUUAGGCCGAA IAUUGGUA
15676





1203
ACCAAUCC C AUUUCAAA
6337
UUUGAAAU CUGAUGAGGCCGUUAGGCCGAA IGAUUGGU
15677





1204
CCAAUCCC A UUUCAAAG
6338
CUUUGAAA CUGAUGAGGCCGUUAGGCCGAA IGGAUUGG
15678





1209
CCCAUUUC A AAGGAGAA
6339
UUCUCCUU CUGAUGAGGCCGUUAGGCCGAA IAAAUGGG
15679





1220
GGAGAAGC A GAGCCAUG
6340
CAUGGCUC CUGAUGAGGCCGUUAGGCCGAA ICUUCUCC
15680





1225
AGCAGAGC C AUGUGGUC
6341
GACCACAU CUGAUGAGGCCGUUAGGCCGAA ICUCUGCU
15681





1226
GCAGAGCC A UGUGGUCU
6342
AGACCACA CUGAUGAGGCCGUUAGGCCGAA IGCUCUGC
15682





1234
AUGUGGUC U CUCUGGUU
6343
AACCAGAG CUGAUGAGGCCGUUAGGCCGAA IACCACAU
15683





1236
GUGGUCUC U CUGGUUGU
6344
ACAACCAG CUGAUGAGGCCGUUAGGCCGAA IAGACCAC
15684





1238
GGUCUCUC U GGUUGUGU
6345
ACACAACC CUGAUGAGGCCGUUAGGCCGAA IAGAGACC
15685





1252
UGUAUGUC C CACCCCAG
6346
CUGGGGUG CUGAUGAGGCCGUUAGGCCGAA IACAUACA
15686





1253
GUAUGUCC C ACCCCAGA
6347
UCUGGGGU CUGAUGAGGCCGUUAGGCCGAA IGACAUAC
15687





1254
UAUGUCCC A CCCCAGAU
6348
AUCUGGGG CUGAUGAGGCCGUUAGGCCGAA IGGACAUA
15688





1256
UGUCCCAC C CCAGAUUG
6349
CAAUCUGG CUGAUGAGGCCGUUAGGCCGAA IUGGGACA
15689





1257
GUCCCACC C CAGAUUGG
6350
CCAAUCUG CUGAUGAGGCCGUUAGGCCGAA IGUGGGAC
15690





1258
UCCCACCC C AGAUUGGU
6351
ACCAAUCU CUGAUGAGGCCGUUAGGCCGAA IGGUGGGA
15691





1259
CCCACCCC A GAUUGGUG
6352
CACCAAUC CUGAUGAGGCCGUUAGGCCGAA IGGGUGUG
15692





1275
GAGAAAUC U CUAAUCUC
6353
GAGAUUAG CUGAUGAGGCCGUUAGGCCGAA IAUUUCUC
15693





1277
GAAAUCUC U AAUCUCUC
6354
GAGAGAUU CUGAUGAGGCCGUUAGGCCGAA IAGAUUUC
15694





1282
CUCUAAUC U CUCCUGUG
6355
CACAGGAG CUGAUGAGGCCGUUAGGCCGAA IAUUAGAG
15695





1284
CUAAUCUC U CCUGUGGA
6356
UCCACAGG CUGAUGAGGCCGUUAGGCCGAA IAGAUUAG
15696





1286
AAUCUCUC C UGUGGAUU
6357
AAUCCACA CUGAUGAGGCCGUUAGGCCGAA IAGAGAUU
15697





1287
AUCUCUCC U GUGGAUUC
6358
GAAUCCAC CUGAUGAGGCCGUUAGGCCGAA IGAGAGAU
15698





1296
GUGGAUUC C UACCAGUA
6359
UACUGGUA CUGAUGAGGCCGUUAGGCCGAA IAAUCCAC
15699





1297
UGGAUUCC U ACCAGUAC
6360
GUACUGGU CUGAUGAGGCCGUUAGGCCGAA IGAAUCCA
15700





1300
AUUCCUAC C AGUACGGC
6361
GCCGUACU CUGAUGAGGCCGUUAGGCCGAA IUAGGAAU
15701





1301
UUCCUACC A GUACGGCA
6362
UGCCGUAC CUGAUGAGGCCGUUAGGCCGAA IGUAGGAA
15702





1309
AGUACGGC A CCACUCAA
6363
UUGAGUGG CUGAUGAGGCCGUUAGGCCGAA ICCGUACU
15703





1311
UACGGCAC C ACUCAAAC
6364
GUUUGAGU CUGAUGAGGCCGUUAGGCCGAA IUGCCGUA
15704





1312
ACGGCACC A CUCAAACG
6365
CGUUUGAG CUGAUGAGGCCGUUAGGCCGAA IGUGCCGU
15705





1314
GGCACCAC U CAAACGCU
6366
AGCGUUUG CUGAUGAGGCCGUUAGGCCGAA IUGGUGCC
15706





1316
CACCACUC A AACGCUGA
6367
UCAGCGUU CUGAUGAGGCCGUUAGGCCGAA IAGUGGUG
15707





1322
UCAAACGC U GACAUGUA
6368
UACAUGUC CUGAUGAGGCCGUUAGGCCGAA ICGUUUGA
15708





1326
ACGCUGAC A UGUACGGU
6369
ACCGUACA CUGAUGAGGCCGUUAGGCCGAA IUCAGCGU
15709





1336
GUACGGUC U AUGCCAUU
6370
AAUGGCAU CUGAUGAGGCCGUUAGGCCGAA IACCGUAC
15710





1341
GUCUAUGC C AUUCCUCC
6371
GGAGGAAU CUGAUGAGGCCGUUAGGCCGAA ICAUAGAC
15711





1342
UCUAUGCC A UUCCUCCC
6372
GGGAGGAA CUGAUGAGGCCGUUAGGCCGAA IGCAUAGA
15712





1346
UGCCAUUC C UCCCCCGC
6373
GCGGGGGA CUGAUGAGGCCGUUAGGCCGAA IAAUGGCA
15713





1347
GCCAUUCC U CCCCCGCA
6374
UGCGGGGG CUGAUGAGGCCGUUAGGCCGAA IGAAUGGC
15714





1349
CAUUCCUC C CCCGCAUC
6375
GAUGCGGG CUGAUGAGGCCGUUAGGCCGAA IAGGAAUG
15715





1350
AUUCCUCC C CCCCAUCA
6376
UGAUGCGG CUGAUGAGGCCGUUAGGCCGAA IGAGGAAU
15716





1351
UUCCUCCC C CCCAUCAC
6377
GUGAUGCG CUGAUGAGGCCGUUAGGCCGAA IGGAGGAA
15717





1352
UCCUCCCC C GCAUCACA
6378
UGUGAUGC CUGAUGAGGCCGUUAGGCCGAA IGGGAGGA
15718





1355
UCCCCCGC A UCACAUCC
6379
GGAUGUGA CUGAUGAGGCCGUUAGGCCGAA ICGGGGGA
15719





1358
CCCGCAUC A CAUCCACU
6380
AGUGGAUG CUGAUGAGGCCGUUAGGCCGAA IAUGCGGG
15720





1360
CGCAUCAC A UCCACUGG
6381
CCAGUGGA CUGAUGAGGCCGUUAGGCCGAA IUGAUGCG
15721





1363
AUCACAUC C ACUGGUAU
6382
AUACCAGU CUGAUGAGGCCGUUAGGCCGAA IAUGUGAU
15722





1364
UCACAUCC A CUGGUAUU
6383
AAUACCAG CUGAUGAGGCCGUUAGGCCGAA IGAUGUGA
15723





1366
ACAUCCAC U GGUAUUGG
6384
CCAAUACC CUGAUGAGGCCGUUAGGCCGAA IUGGAUGU
15724





1376
GUAUUGGC A GUUGGAGG
6385
CCUCCAAC CUGAUGAGGCCGUUAGGCCGAA ICCAAUAC
15725





1395
GAGUGCGC C AACGAGCC
6386
GGCUCGUU CUGAUGAGGCCGUUAGGCCGAA ICGCACUC
15726





1396
AGUGCGCC A ACGAGCCC
6387
GGGCUCGU CUGAUGAGGCCGUUAGGCCGAA IGCGCACU
15727





1403
CAACGAGC C CAGCCAAG
6388
CUUGGCUG CUGAUGAGGCCGUUAGGCCGAA ICUCGUUG
15728





1404
AACGAGCC C AGCCAAGC
6389
GCUUGGCU CUGAUGAGGCCGUUAGGCCGAA IGCUCGUU
15729





1405
ACGAGCCC A GCCAAGCU
6390
AGCUUGGC CUGAUGAGGCCGUUAGGCCGAA IGGCUCGU
15730





1408
AGCCCAGC C AAGCUGUC
6391
GACAGCUU CUGAUGAGGCCGUUAGGCCGAA ICUGGGCU
15731





1409
GCCCAGCC A AGCUGUCU
6392
AGACAGCU CUGAUGAGGCCGUUAGGCCGAA IGCUGGGC
15732





1413
AGCCAAGC U GUCUCAGU
6393
ACUGAGAC CUGAUGAGGCCGUUAGGCCGAA ICUUGGCU
15733





1417
AAGCUGUC U CAGUGACA
6394
UGUCACUG CUGAUGAGGCCGUUAGGCCGAA IACAGCUU
15734





1419
GCUGUCUC A GUGACAAA
6395
UUUGUCAC CUGAUGAGGCCGUUAGGCCGAA IAGACAGC
15735





1425
UCAGUGAC A AACCCAUA
6396
UAUGGGUU CUGAUGAGGCCGUUAGGCCGAA IUCACUGA
15736





1429
UGACAAAC C CAUACCCU
6397
AGGGUAUG CUGAUGAGGCCGUUAGGCCGAA IUUUGUCA
15737





1430
GACAAACC C AUACCCUU
6398
AAGGGUAU CUGAUGAGGCCGUUAGGCCGAA IGUUUGUC
15738





1431
ACAAACCC A UACCCUUG
6399
CAAGGGUA CUGAUGAGGCCGUUAGGCCGAA IGGUUUGU
15739





1435
ACCCAUAC C CUUGUGAA
6400
UUCACAAG CUGAUGAGGCCGUUAGGCCGAA IUAUGGGU
15740





1436
CCCAUACC C UUGUGAAG
6401
CUUCACAA CUGAUGAGGCCGUUAGGCCGAA IGUAUGGG
15741





1437
CCAUACCC U UGUGAAGA
6402
UCUUCACA CUGAUGAGGCCGUUAGGCCGAA IGGUAUGG
15742





1465
UGGAGGAC U UCCAGGGA
6403
UCCCUGGA CUGAUGAGGCCGUUAGGCCGAA IUCCUCCA
15743





1468
AGGACUUC C AGGGAGGA
6404
UCCUCCCU CUGAUGAGGCCGUUAGGCCGAA IAAGUCCU
15744





1469
GGACUUCC A GGGAGGAA
6405
UUCCUCCC CUGAUGAGGCCGUUAGGCCGAA IGAAGUCC
15745





1502
UAAAAAUC A AUUUGCUC
6406
GAGCAAAU CUGAUGAGGCCGUUAGGCCGAA IAUUUUUA
15746





1509
CAAUUUGC U CUAAUUGA
6407
UCAAUUAG CUGAUGAGGCCGUUAGGCCGAA ICAAAUUG
15747





1511
AUUUGCUC U AAUUGAAG
6408
CUUCAAUU CUGAUGAGGCCGUUAGGCCGAA IAGCAAAU
15748





1528
GAAAAAAC A AAACUGUA
6409
UACAGUUU CUGAUGAGGCCGUUAGGCCGAA IUUUUUUC
15749





1533
AACAAAAC U GUAAGUAC
6410
GUACUUAC CUGAUGAGGCCGUUAGGCCGAA IUUUUGUU
15750





1542
GUAAGUAC C CUUGUUAU
6411
AUAACAAG CUGAUGAGGCCGUUAGGCCGAA IUACUUAC
15751





1543
UAAGUACC C UUGUUAUC
6412
GAUAACAA CUGAUGAGGCCGUUAGGCCGAA IGUACUUA
15752





1544
AAGUACCC U UGUUAUCC
6413
GGAUAACA CUGAUGAGGCCGUUAGGCCGAA IGGUACUU
15753





1552
UUGUUAUC C AAGCGGCA
6414
UGCCGCUU CUGAUGAGGCCGUUAGGCCGAA IAUAACAA
15754





1553
UGUUAUCC A AGCGGCAA
6415
UUGCCGCU CUGAUGAGGCCGUUAGGCCGAA IGAUAACA
15755





1560
CAAGCGGC A AAUGUGUC
6416
GACACAUU CUGAUGAGGCCGUUAGGCCGAA ICCGCUUG
15756





1569
AAUGUGUC A GCUUUGUA
6417
UACAAAGC CUGAUGAGGCCGUUAGGCCGAA IACACAUU
15757





1572
GUGUCAGC U UUGUACAA
6418
UUGUACAA CUGAUGAGGCCGUUAGGCCGAA ICUGACAC
15758





1579
CUUUGUAC A AAUGUGAA
6419
UUCACAUU CUGAUGAGGCCGUUAGGCCGAA IUACAAAG
15759





1594
AAGCGGUC A ACAAAGUC
6420
GACUUUGU CUGAUGAGGCCGUUAGGCCGAA IACCGCUU
15760





1597
CGGUCAAC A AAGUCGGG
6421
CCCGACUU CUGAUGAGGCCGUUAGGCCGAA IUUGACCG
15761





1624
GGGUGAUC U CCUUCCAC
6422
GUGGAAGG CUGAUGAGGCCGUUAGGCCGAA IAUCACCC
15762





1626
GUGAUCUC C UUCCACGU
6423
ACGUGGAA CUGAUGAGGCCGUUAGGCCGAA IAGAUCAC
15763





1627
UGAUCUCC U UCCACGUG
6424
CACGUGGA CUGAUGAGGCCGUUAGGCCGAA IGAGAUCA
15764





1630
UCUCCUUC C ACGUGACC
6425
GGUCACGU CUGAUGAGGCCGUUAGGCCGAA IAAGGAGA
15765





1631
CUCCUUCC A CGUGACCA
6426
UGGUCACG CUGAUGAGGCCGUUAGGCCGAA IGAAGGAG
15766





1638
CACGUGAC C AGGGGUCC
6427
GGACCCCU CUGAUGAGGCCGUUAGGCCGAA IUCACGUG
15767





1639
ACGUGACC A GGGGUCCU
6428
AGGACCCC CUGAUGAGGCCGUUAGGCCGAA IGUCACGU
15768





1646
CAGGGGUC C UGAAAUUA
6429
UAAUUUCA CUGAUGAGGCCGUUAAGCCCGA IACCCCUG
15769





1647
AGGGGUCC U GAAAUUAC
6430
GUAAUUUC CUGAUGAGGCCGUUAGGCCGAA IGACCCCU
15770





1656
GAAAUUAC U UUGCAACC
6431
GGUUGCAA CUGAUGAGGCCGUUAGGCCGAA IUAAUUUC
15771





1661
UACUUUGC A ACCUGACA
6432
UGUCAGGU CUGAUGAGGCCGUUAGGCCGAA ICAAAGUA
15772





1664
UUUGCAAC C UGACAUGC
6433
GCAUGUCA CUGAUGAGGCCGUUAGGCCGAA IUUGCAAA
15773





1665
UUGCAACC U GACAUGCA
6434
UGCAUGUC CUGAUGAGGCCGUUAGGCCGAA IGUUGCAA
15774





1669
AACCUGAC A UGCAGCCC
6435
GGGCUGCA CUGAUGAGGCCGUUAGGCCGAA IUCAGGUU
15775





1673
UGACAUGC A GCCCACUG
6436
CAGUGGGC CUGAUGAGGCCGUUAGGCCGAA ICAUGUCA
15776





1676
CAUGCAGC C CACUGAGC
6437
GCUCAGUG CUGAUGAGGCCGUUAGGCCGAA ICUGCAUG
15777





1677
AUGCAGCC C ACUGAGCA
6438
UGCUCAGU CUGAUGAGGCCGUUAGGCCGAA IGCUGCAU
15778





1678
UGCAGCCC A CUGAGCAG
6439
CUGCUCAG CUGAUGAGGCCGUUAGGCCGAA IGGCUGCA
15779





1680
CAGCCCAC U GAGCAGGA
6440
UCCUGCUC CUGAUGAGGCCGUUAGGCCGAA IUGGGCUG
15780





1685
CACUGAGC A GGAGAGCG
6441
CGCUCUCC CUGAUGAGGCCGUUAGGCCGAA ICUCAGUG
15781





1698
AGCGUGUC U UUGUGGUG
6442
CACCACAA CUGAUGAGGCCGUUAGGCCGAA IACACGCU
15782





1708
UGUGGUGC A CUGCAGAC
6443
GUCUGCAG CUGAUGAGGCCGUUAGGCCGAA ICACCACA
15783





1710
UGGUGCAC U GCAGACAG
6444
CUGUCUGC CUGAUGAGGCCGUUAGGCCGAA IUGCACCA
15784





1713
UGCACUGC A GACAGAUC
6445
GAUCUGUC CUGAUGAGGCCGUUAGGCCGAA ICAGUGCA
15785





1717
CUGCAGAC A GAUCUACG
6446
CGUAGAUC CUGAUGAGGCCGUUAGGCCGAA IUCUGCAG
15786





1722
GACAGAUC U ACGUUUGA
6447
UCAAACGU CUGAUGAGGCCGUUAGGCCGAA IAUCUGUC
15787





1735
UUGAGAAC C UCACAUGG
6448
CCAUGUGA CUGAUGAGGCCGUUAGGCCGAA IUUCUCAA
15788





1736
UGAGAACC U CACAUGGU
6449
ACCAUGUG CUGAUGAGGCCGUUAGGCCGAA IGUUCUCA
15789





1738
AGAACCUC A CAUGGUAC
6450
GUACCAUG CUGAUGAGGCCGUUAGGCCGAA IAGGUUCU
15790





1740
AACCUCAC A UGGUACAA
6451
UUGUACCA CUGAUGAGGCCGUUAGGCCGAA IUGAGGUU
15791





1747
CAUGGUAC A AGCUUGGC
6452
GCCAAGCU CUGAUGAGGCCGUUAGGCCGAA IUACCAUG
15792





1751
GUACAAGC U UGGCCCAC
6453
GUGGGCCA CUGAUGAGGCCGUUAGGCCGAA ICUUGUAC
15793





1756
AGCUUGGC C CACAGCCU
6454
AGGCUGUG CUGAUGAGGCCGUUAGGCCGAA ICCAAGCU
15794





1757
GCUUGGCC C ACAGCCUC
6455
GAGGCUGU CUGAUGAGGCCGUUAGGCCGAA IGCCAAGC
15795





1758
CUUGGCCC A CAGCCUCU
6456
AGAGGCUG CUGAUGAGGCCGUUAGGCCGAA IGGCCAAG
15796





1760
UGGCCCAC A GCCUCUGC
6457
GCAGAGGC CUGAUGAGGCCGUUAGGCCGAA IUGGGCCA
15797





1763
CCCACAGC C UCUGCCAA
6458
UUGGCAGA CUGAUGAGGCCGUUAGGCCGAA ICUGUGGG
15798





1764
CCACAGCC U CUGCCAAU
6459
AUUGGCAG CUGAUGAGGCCGUUAGGCCGAA IGCUGUGG
15799





1766
ACAGCCUC U GCCAAUCC
6460
GGAUUGGC CUGAUGAGGCCGUUAGGCCGAA IAGGCUGU
15800





1769
GCCUCUGC C AAUCCAUG
6461
CAUGGAUU CUGAUGAGGCCGUUAGGCCGAA ICAGAGGC
15801





1770
CCUCUGCC A AUCCAUGU
6462
ACAUGGAU CUGAUGAGGCCGUUAGGCCGAA IGCAGAGG
15802





1774
UGCCAAUC C AUGUGGGA
6463
UCCCACAU CUGAUGAGGCCGUUAGGCCGAA IAUUGGCA
15803





1775
GCCAAUCC A UGUGGGAG
6464
CUCCCACA CUGAUGAGGCCGUUAGGCCGAA IGAUUGGC
15804





1790
AGAGUUGC C CACACCUG
6465
CAGGUGUG CUGAUGAGGCCGUUAGGCCGAA ICAACUCU
15805





1791
GAGUUGCC C ACACCUGU
6466
ACAGGUGU CUGAUGAGGCCGUUAGGCCGAA IGCAACUC
15806





1792
AGUUGCCC A CACCUGUU
6467
AACAGGUG CUGAUGAGGCCGUUAGGCCGAA IGGCAACU
15807





1794
UUGCCCAC A CCUGUUUG
6468
CAAACAGG CUGAUGAGGCCGUUAGGCCGAA IUGGGCAA
15808





1796
GCCCACAC C UGUUUGCA
6469
UGCAAACA CUGAUGAGGCCGUUAGGCCGAA IUGUGGGC
15809





1797
CCCACACC U GUUUGCAA
6470
UUGCAAAC CUGAUGAGGCCGUUAGGCCGAA IGUGUGGG
15810





1804
CUGUUUGC A AGAACUUG
6471
CAAGUUCU CUGAUGAGGCCGUUAGGCCGAA ICAAACAG
15811





1810
GCAAGAAC U UGGAUACU
6472
AGUAUCCA CUGAUGAGGCCGUUAGGCCGAA IUUCUUGC
15812





1818
UUGGAUAC U CUUUGGAA
6473
UUCCAAAG CUGAUGAGGCCGUUAGGCCGAA IUAUCCAA
15813





1820
GGAUACUC U UUGGAAAU
6474
AUUUCCAA CUGAUGAGGCCGUUAGGCCGAA IAGUAUCC
15814





1836
UUGAAUGC C ACCAUGUU
6475
AACAUGGU CUGAUGAGGCCGUUAGGCCGAA ICAUUCAA
15815





1837
UGAAUGCC A CCAUGUUC
6476
GAACAUGG CUGAUGAGGCCGUUAGGCCGAA IGCAUUCA
15816





1839
AAUGCCAC C AUGUUCUC
6477
GAGAACAU CUGAUGAGGCCGUUAGGCCGAA IUGGCAUU
15817





1840
AUGCCACC A UGUUCUCU
6478
AGAGAACA CUGAUGAGGCCGUUAGGCCGAA IGUGGCAU
15818





1846
CCAUGUUC U CUAAUAGC
6479
GCUAUUAG CUGAUGAGGCCGUUAGGCCGAA IAACAUGG
15819





1848
AUGUUCUC U AAUAGCAC
6480
GUGCUAUU CUGAUGAGGCCGUUAGGCCGAA IAGAACAU
15820





1855
CUAAUAGC A CAAAUGAC
6481
GUCAUUUG CUGAUGAGGCCGUUAGGCCGAA ICUAUUAG
15821





1857
AAUAGCAC A AAUGACAU
6482
AUGUCAUU CUGAUGAGGCCGUUAGGCCGAA IUGCUAUU
15822





1864
CAAAUGAC A UUUUGAUC
6483
GAUCAAAA CUGAUGAGGCCGUUAGGCCGAA IUCAUUUG
15823





1873
UUUUGAUC A UGGAGCUU
6484
AAGCUCCA CUGAUGAGGCCGUUAGGCCGAA IAUCAAAA
15824





1880
CAUGGAGC U UAAGAAUG
6485
CAUUCUUA CUGAUGAGGCCGUUAGGCCGAA ICUCCAUG
15825





1890
AAGAAUGC A UCCUUGCA
6486
UGCAAGGA CUGAUGAGGCCGUUAGGCCGAA ICAUUCUU
15826





1893
AAUGCAUC C UUGCAGGA
6487
UCCUGCAA CUGAUGAGGCCGUUAGGCCGAA IAUGCAUU
15827





1894
AUGCAUCC U UGCAGGAC
6488
GUCCUGCA CUGAUGAGGCCGUUAGGCCGAA IGAUGCAU
15828





1898
AUCCUUGC A GGACCAAG
6489
CUUGGUCC CUGAUGAGGCCGUUAGGCCGAA ICAAGGAU
15829





1903
UGCAGGAC C AAGGAGAC
6490
GUCUCCUU CUGAUGAGGCCGUUAGGCCGAA IUCCUGCA
15830





1904
GCAGGACC A AGGAGACU
6491
AGUCUCCU CUGAUGAGGCCGUUAGGCCGAA IGUCCUGC
15831





1912
AAGGAGAC U AUGUCUGC
6492
GCAGACAU CUGAUGAGGCCGUUAGGCCGAA IUCUCCUU
15832





1918
ACUAUGUC U GCCUUGCU
6493
AGCAAGGC CUGAUGAGGCCGUUAGGCCGAA IACAUAGU
15833





1921
AUGUCUGC C UUGCUCAA
6494
UUGAGCAA CUGAUGAGGCCGUUAGGCCGAA ICAGACAU
15834





1922
UGUCUGCC U UGCUCAAG
6495
CUUGAGCA CUGAUGAGGCCGUUAGGCCGAA IGCAGACA
15835





1926
UGCCUUGC U CAAGACAG
6496
CUGUCUUG CUGAUGAGGCCGUUAGGCCGAA ICAAGGCA
15836





1928
CCUUGCUC A AGACAGGA
6497
UCCUGUCU CUGAUGAGGCCGUUAGGCCGAA IAGCAAGG
15837





1933
CUCAAGAC A GGAAGACC
6498
GGUCUUCC CUGAUGAGGCCGUUAGGCCGAA IUCUUGAG
15838





1941
AGGAAGAC C AAGAAAAG
6499
CUUUCUUU CUGAUGAGGCCGUUAGGCCGAA IUCUUCCU
15839





1942
GGAAGACC A AGAAAAGA
6500
UCUUUUCU CUGAUGAGGCCGUUAGGCCGAA IGUCUUCC
15840





1952
GAAAAGAC A UUGCGUGG
6501
CCACGCAA CUGAUGAGGCCGUUAGGCCGAA IUCUUUUC
15841





1963
GCGUGGUC A GGCAGCUC
6502
GAGCUGCC CUGAUGAGGCCGUUAGGCCGAA IACCACGC
15842





1967
GGUCAGGC A GCUCACAG
6503
CUGUGAGC CUGAUGAGGCCGUUAGGCCGAA ICCUGACC
15843





1970
CAGGCAGC U CACAGUCC
6504
GGACUGUG CUGAUGAGGCCGUUAGGCCGAA ICUGCCUG
15844





1972
GGCAGCUC A CAGUCCUA
6505
UAGGACUG CUGAUGAGGCCGUUAGGCCGAA IAGCUGCC
15845





1974
CAGCUCAC A GUCCUAGA
6506
UCUAGGAC CUGAUGAGGCCGUUAGGCCGAA IUGAGCUG
15846





1978
UCACAGUC C UAGAGCGU
6507
ACGCUCUA CUGAUGAGGCCGUUAGGCCGAA IACUGUGA
15847





1979
CACAGUCC U AGAGCGUG
6508
CACGCUCU CUGAUGAGGCCGUUAGGCCGAA IGACUGUG
15848





1992
CGUGUGGC A CCCACGAU
6509
AUCGUGGG CUGAUGAGGCCGUUAGGCCGAA ICCACACG
15849





1994
UGUGGCAC C CACGAUCA
6510
UGAUCGUG CUGAUGAGGCCGUUAGGCCGAA IUGCCACA
15850





1995
GUGGCACC C ACGAUCAC
6511
GUGAUCGU CUGAUGAGGCCGUUAGGCCGAA IGUGCCAC
15851





1996
UGGCACCC A CGAUCACA
6512
UGUGAUCG CUGAUGAGGCCGUUAGGCCGAA IGGUGCCA
15852





2002
CCACGAUC A CAGGAAAC
6513
GUUUCCUG CUGAUGAGGCCGUUAGGCCGAA IAUCGUGG
15853





2004
ACGAUCAC A GGAAACCU
6514
AGGUUUCC CUGAUGAGGCCGUUAGGCCGAA IUGAUCGU
15854





2011
CAGGAAAC C UGGAGAAU
6515
AUUCUCCA CUGAUGAGGCCGUUAGGCCGAA IUUUCCUG
15855





2012
AGGAAACC U GGAGAAUC
6516
GAUUCUCC CUGAUGAGGCCGUUAGGCCGAA IGUUUCCU
15856





2021
GGAGAAUC A GACGACAA
6517
UUGUCGUC CUGAUGAGGCCGUUAGGCCGAA IAUUCUCC
15857





2028
CAGACGAC A AGUAUUGG
6518
CCAAUACU CUGAUGAGGCCGUUAGGCCGAA IUCGUCUG
15858





2044
GGGAAAGC A UCGAAGUC
6519
GACUUCGA CUGAUGAGGCCGUUAGGCCGAA ICUUUCCC
15859





2053
UCGAAGUC U CAUGCACG
6520
CGUGCAUG CUGAUGAGGCCGUUAGGCCGAA IACUUCGA
15860





2055
GAAGUCUC A UGCACGGC
6521
GCCGUGCA CUGAUGAGGCCGUUAGGCCGAA IAGACUUC
15861





2059
UCUCAUGC A CGGCAUCU
6522
AGAUGCCG CUGAUGAGGCCGUUAGGCCGAA ICAUGAGA
15862





2064
UGCACGGC A UCUGGGAA
6523
UUCCCAGA CUGAUGAGGCCGUUAGGCCGAA ICCGUGCA
15863





2067
ACGGCAUC U GGGAAUCC
6524
GGAUUCCC CUGAUGAGGCCGUUAGGCCGAA IAUGCCGU
15864





2075
UGGGAAUC C CCCUCCAC
6525
GUGGAGGG CUGAUGAGGCCGUUAGGCCGAA IAUUCCCA
15865





2076
GGGAAUCC C CCUCCACA
6526
UGUGGAGO CUGAUGAGGCCGUUAGGCCGAA IGAUUCCC
15866





2077
GGAAUCCC C CUCCACAG
6527
CUGUGGAG CUGAUGAGGCCGUUAGGCCGAA IGGAUUCC
15867





2078
GAAUCCCC C UCCACAGA
6528
UCUGUGGA CUGAUGAGGCCGUUAGGCCGAA IGGGAUUC
15868





2079
AAUCCCCC U CCACAGAU
6529
AUCUGUGG CUGAUGAGGCCGUUAGGCCGAA IGGGGAUU
15869





2081
UCCCCCUC C ACAGAUCA
6530
UGAUCUGU CUGAUGAGGCCGUUAGGCCGAA IAGGGGGA
15870





2082
CCCCCUCC A CAGAUCAU
6531
AUGAUCUG CUGAUGAGGCCGUUAGGCCGAA IGAGGGGG
15871





2084
CCCUCCAC A GAUCAUGU
6532
ACAUGAUC CUGAUGAGGCCGUUAGGCCGAA IUGGAGGG
15872





2089
CACAGAUC A UGUGGUUU
6533
AAACCACA CUGAUGAGGCCGUUAGGCCGAA IAUCUGUG
15873





2112
AAUGAGAC C CUUGUAGA
6534
UCUACAAG CUGAUGAGGCCGUUAGGCCGAA IUCUCAUU
15874





2113
AUGAGACC C UUGUAGAA
6535
UUCUACAA CUGAUGAGGCCGUUAGGCCGAA IGUCUCAU
15875





2114
UGAGACCC U UGUAGAAG
6536
CUUCUACA CUGAUGAGGCCGUUAGGCCGAA IGGUCUCA
15876





2125
UAGAAGAC U CAGGCAUU
6537
AAUGCCUG CUGAUGAGGCCGUUAGGCCGAA IUCUUCUA
15877





2127
GAAGACUC A GGCAUUGU
6538
ACAAUGCC CUGAUGAGGCCGUUAGGCCGAA IAGUCUUC
15878





2131
ACUCAGGC A UUGUAUUG
6539
CAAUACAA CUGAUGAGGCCGUUAGGCCGAA ICCUGAGU
15879





2152
AUGGGAAC C GGAACCUC
6540
GAGGUUCC CUGAUGAGGCCGUUAGGCCGAA IUUCCCAU
15880





2158
ACCGGAAC C UCACUAUC
6541
GAUAGUGA CUGAUGAGGCCGUUAGGCCGAA IUUCCGGU
15881





2159
CCGGAACC U CACUAUCC
6542
GGAUAGUG CUGAUGAGGCCGUUAGGCCGAA IGUUCCGG
15882





2161
GGAACCUC A CUAUCCGC
6543
GCGGAUAG CUGAUGAGGCCGUUAGGCCGAA IAGGUUCC
15883





2163
AACCUCAC U AUCCGCAG
6544
CUGCGGAU CUGAUGAGGCCGUUAGGCCGAA IUGAGGUU
15884





2167
UCACUAUC C GCAGAGUG
6545
CACUCUGC CUGAUGAGGCCGUUAGGCCGAA IAUAGUGA
15885





2170
CUAUCCGC A GAGUGAGG
6546
CCUCACUC CUGAUGAGGCCGUUAGGCCGAA ICGGAUAG
15886





2194
ACGAAGGC C UCUACACC
6547
GGUGUAGA CUGAUGAGGCCGUUAGGCCGAA ICCUUCGU
15887





2195
CGAAGGCC U CUACACCU
6548
AGGUGUAG CUGAUGAGGCCGUUAGGCCGAA IGCCUUCG
15888





2197
AAGGCCUC U ACACCUGC
6549
GCAGGUGU CUGAUGAGGCCGUUAGGCCGAA IAGGCCUU
15889





2200
GCCUCUAC A CCUGCCAG
6550
CUGGCAGG CUGAUGAGGCCGUUAGGCCGAA IUAGAGGC
15890





2202
CUCUACAC C UGCCAGGC
6551
GCCUGGCA CUGAUGAGGCCGUUAGGCCGAA IUGUAGAG
15891





2203
UCUACACC U GCCAGGCA
6552
UGCCUGGC CUGAUGAGGCCGUUAGGCCGAA IGUGUAGA
15892





2206
ACACCUGC C AGGCAUGC
6553
GCAUGCCU CUGAUGAGGCCGUUAGGCCGAA ICAGGUGU
15893





2207
CACCUGCC A GGCAUGCA
6554
UGCAUGCC CUGAUGAGGCCGUUAGGCCGAA IGCAGGUG
15894





2211
UGCCAGGC A UGCAGUGU
6555
ACACUGCA CUGAUGAGGCCGUUAGGCCGAA ICCUGGCA
15895





2215
AGGCAUGC A GUGUUCUU
6556
AAGAACAC CUGAUGAGGCCGUUAGGCCGAA ICAUGCCU
15896





2222
CAGUGUUC U UGGCUGUG
6557
CACAGCCA CUGAUGAGGCCGUUAGGCCGAA IAACACUG
15897





2227
UUCUUGGC U GUGCAAAA
6558
UUUUGCAC CUGAUGAGGCCGUUAGGCCGAA ICCAAGAA
15898





2232
GGCUGUGC A AAAGUGGA
6559
UCCACUUU CUGAUGAGGCCGUUAGGCCGAA ICACAGCC
15899





2244
GUGGAGGC A UUUUUCAU
6560
AUGAAAAA CUGAUGAGGCCGUUAGGCCGAA ICCUCCAC
15900





2251
CAUUUUUC A UAAUAGAA
6561
UUCUAUUA CUGAUGAGGCCGUUAGGCCGAA IAAAAAUG
15901





2265
GAAGGUGC C CAGGAAAA
6562
UUUUCCUG CUGAUGAGGCCGUUAGGCCGAA ICACCUUC
15902





2266
AAGGUGCC C AGGAAAAG
6563
CUUUUCCU CUGAUGAGGCCGUUAGGCCGAA IGCACCUU
15903





2267
AGGUGCCC A GGAAAAGA
6564
UCUUUUCC CUGAUGAGGCCGUUAGGCCGAA IGGCACCU
15904





2281
AGACGAAC U UGGAAAUC
6565
GAUUUCCA CUGAUGAGGCCGUUAGGCCGAA IUUCGUCU
15905





2290
UGGAAAUC A UUAUUCUA
6566
UAGAAUAA CUGAUGAGGCCGUUAGGCCGAA IAUUUCCA
15906





2297
CAUUAUUC U AGUAGGCA
6567
UGCCUACU CUGAUGAGGCCGUUAGGCCGAA IAAUAAUG
15907





2305
UAGUAGGC A CGACGGUG
6568
CACCGUCG CUGAUGAGGCCGUUAGGCCGAA ICCUACUA
15908





2319
GUGAUUGC C AUGUUCUU
6569
AAGAACAU CUGAUGAGGCCGUUAGGCCGAA ICAAUCAC
15909





2320
UGAUUGCC A UGUUCUUC
6570
GAAGAACA CUGAUGAGGCCGUUAGGCCGAA IGCAAUCA
15910





2326
CCAUGUUC U UCUGGCUA
6571
UAGCCAGA CUGAUGAGGCCGUUAGGCCGAA IAACAUGG
15911





2329
UGUUCUUC U GGCUACUU
6572
AAGUAGCC CUGAUGAGGCCGUUAGGCCGAA IAAGAACA
15912





2333
CUUCUGGC U ACUUCUUG
6573
CAAGAAGU CUGAUGAGGCCGUUAGGCCGAA ICCAGAAG
15913





2336
CUGGCUAC U UCUUGUCA
6574
UGACAAGA CUGAUGAGGCCGUUAGGCCGAA IUAGCCAG
15914





2339
GCUACUUC U UGUCAUCA
6575
UGAUGACA CUGAUGAGGCCGUUAGGCCGAA IAAGUAGC
15915





2344
UUCUUGUC A UCAUCCUA
6576
UAGGAUGA CUGAUGAGGCCGUUAGGCCGAA IACAAGAA
15916





2347
UUGUCAUC A UCCUAGGG
6577
CCCUAGGA CUGAUGAGGCCGUUAGGCCGAA IAUGACAA
15917





2350
UCAUCAUC C UAGGGACC
6578
GGUCCCUA CUGAUGAGGCCGUUAGGCCGAA IAUGAUGA
15918





2351
CAUCAUCC U AGGGACCG
6579
CGGUCCCU CUGAUGAGGCCGUUAGGCCGAA IGAUGAUG
15919





2358
CUAGGGAC C GUUAAGCG
6580
CGCUUAAC CUGAUGAGGCCGUUAGGCCGAA IUCCCUAG
15920





2370
AAGCGGGC C AAUGGAGG
6581
CCUCCAUU CUGAUGAGGCCGUUAGGCCGAA ICCCGCUU
15921





2371
AGCGGGCC A AUGGAGGG
6582
CCCUCCAU CUGAUGAGGCCGUUAGGCCGAA IGCCCGCU
15922





2384
AGGGGAAC U GAAGACAG
6583
CUGUCUUC CUGAUGAGGCCGUUAGGCCGAA IUUCCCCU
15923





2391
CUGAAGAC A GGCUACUU
6584
AAGUAGCC CUGAUGAGGCCGUUAGGCCGAA IUCUUCAG
15924





2395
AGACAGGC U ACUUGUCC
6585
GGACAAGU CUGAUGAGGCCGUUAGGCCGAA ICCUGUCU
15925





2398
CAGGCUAC U UGUCCAUC
6586
GAUGGACA CUGAUGAGGCCGUUAGGCCGAA IUAGCCUG
15926





2403
UACUUGUC C AUCGUCAU
6587
AUGACGAU CUGAUGAGGCCGUUAGGCCGAA IACAAGUA
15927





2404
ACUUGUCC A UCGUCAUG
6588
CAUGACGA CUGAUGAGGCCGUUAGGCCGAA IGACAAGU
15928





2410
CCAUCGUC A UGGAUCCA
6589
UGGAUCCA CUGAUGAGGCCGUUAGGCCGAA IACGAUGG
15929





2417
CAUGGAUC C AGAUGAAC
6590
GUUCAUCU CUGAUGAGGCCGUUAGGCCGAA IAUCCAUG
15930





2418
AUGGAUCC A GAUGAACU
6591
AGUUCAUC CUGAUGAGGCCGUUAGGCCGAA IGAUCCAU
15931





2426
AGAUGAAC U CCCAUUGG
6592
CCAAUGGG CUGAUGAGGCCGUUAGGCCGAA IUUCAUCU
15932





2428
AUGAACUC C CAUUGGAU
6593
AUCCAAUG CUGAUGAGGCCGUUAGGCCGAA IAGUUCAU
15933





2429
UGAACUCC C AUUGGAUG
6594
CAUCCAAU CUGAUGAGGCCGUUAGGCCGAA IGAGUUCA
15934





2430
GAACUCCC A UUGGAUGA
6595
UCAUCCAA CUGAUGAGGCCGUUAGGCCGAA IGGAGUUC
15935





2441
GGAUGAAC A UUGUGAAC
6596
GUUCACAA CUGAUGAGGCCGUUAGGCCGAA IUUCAUCC
15936





2453
UGAACGAC U GCCUUAUG
6597
CAUAAGGC CUGAUGAGGCCGUUAGGCCGAA IUCGUUCA
15937





2456
ACGACUGC C UUAUGAUG
6598
CAUCAUAA CUGAUGAGGCCGUUAGGCCGAA ICAGUCGU
15938





2457
CGACUGCC U UAUGAUGC
6599
GCAUCAUA CUGAUGAGGCCGUUAGGCCGAA IGCAGUCG
15939





2466
UAUGAUGC C AGCAAAUG
6600
CAUUUGCU CUGAUGAGGCCGUUAGGCCGAA ICAUCAUA
15940





2467
AUGAUGCC A GCAAAUGG
6601
CCAUUUGC CUCAUGAGGCCGUUAGGCCGAA IGCAUCAU
15941





2470
AUGCCAGC A AAUGGGAA
6602
UUCCCAUU CUGAUGAGGCCGUUAGGCCGAA ICUGGCAU
15942





2482
GGGAAUUC C CCAGAGAC
6603
GUCUCUGG CUGAUGAGGCCGUUAGGCCGAA IAAUUCCC
15943





2483
GGAAUUCC C CAGAGACC
6604
GGUCUCUG CUGAUGAGGCCGUUAGGCCGAA IGAAUUCC
15944





2484
GAAUUCCC C AGAGACCG
6605
CGGUCUCU CUGAUGAGGCCGUUAGGCCGAA IGGAAUUC
15945





2485
AAUUCCCC A GAGACCGG
6606
CCGGUCUC CUGAUGAGGCCGUUAGGCCGAA IGGGAAUU
15946





2491
CCAGAGAC C GGCUGAAC
6607
GUUCAGCC CUGAUGAGGCCGUUAGGCCGAA IUCUCUGG
15947





2495
AGACCGGC U GAACCUAG
6608
CUAGGUUC CUGAUGAGGCCGUUAGGCCGAA ICCGGUCU
15948





2500
GGCUGAAC C UAGGUAAG
6609
CUUACCUA CUGAUGAGGCCGUUAGGCCGAA IUUCAGCC
15949





2501
GCUGAACC U AGGUAAGC
6610
GCUUACCU CUGAUGAGGCCGUUAGGCCGAA IGUUCAGC
15950





2510
AGGUAAGC C UCUUGGCC
6611
GGCCAAGA CUCAUGAGGCCGUUAGGCCGAA ICUUACCU
15951





2511
GGUAAGCC U CUUGGCCG
6612
CGGCCAAG CUGAUGAGGCCGUUAGGCCGAA IGCUUACC
15952





2513
UAAGCCUC U UGGCCGUG
6613
CACGGCCA CUGAUGAGGCCGUUAGGCCGAA IAGGCUUA
15953





2518
CUCUUGGC C GUGGUGCC
6614
GGCACCAC CUGAUGAGGCCGUUAGGCCGAA ICCAAGAG
15954





2526
CGUGGUGC C UUUGGCCA
6615
UGGCCAAA CUGAUGAGGCCGUUAGGCCGAA ICACCACO
15955





2527
GUGGUGCC U UUGGCCAA
6616
UUGGCCAA CUGAUGAGGCCGUUAGGCCGAA IGCACCAC
15956





2533
CCUUUGGC C AAGAGAUU
6617
AAUCUCUU CUGAUGAGGCCGUUAGGCCGAA ICCAAAGG
15957





2534
CUUUGGCC A AGAGACUG
6618
CAAUCUCU CUGAUGAGGCCGUUAGGCCGAA IGCCAAAG
15958





2547
AUUGAAGC A GAUGCCUU
6619
AAGGCAUC CUGAUGAGGCCGUUAGGCCGAA ICUUCAAU
15959





2553
GCAGAUGC C UUUGGAAU
6620
AUUCCAAA CUGAUGAGGCCGUUAGGCCGAA ICAUCUGC
15960





2554
CAGAUGCC U UUGGAAUU
6621
AAUUCCAA CUGAUGAGGCCGUUAGGCCGAA IGCAUCUG
15961





2566
GAAUUGAC A AGACAGCA
6622
UGCUGUCU CUGAUGAGGCCGUUAGGCCGAA IUCAAUUC
15962





2571
GACAAGAC A GCAACUUG
6623
CAAGUUGC CUGAUGAGGCCGUUAGGCCGAA IUCUUGUC
15963





2574
AAGACAGC A ACUUGCAG
6624
CUGCAAGU CUGAUGAGGCCGUUAGGCCGAA ICUGUCUU
15964





2577
ACAGCAAC U UGCAGGAC
6625
GUCCUGCA CUGAUGAGGCCGUUAGGCCGAA IUUGCUGU
15965





2581
CAACUUGC A GGACAGUA
6626
UACUGUCC CUGAUGAGGCCGUUAGGCCGAA ICAAGUUG
15966





2586
UGCAGGAC A GUAGCAGU
6627
ACUGCUAC CUGAUGAGGCCGUUAGGCCGAA IUCCUGCA
15967





2592
ACAGUAGC A GUCAAAAU
6628
AUUUUGAC CUGAUGAGGCCGUUAGGCCGAA ICUACUGU
15968





2596
UAGCAGUC A AAAUGUUG
6629
CAACAUUU CUGAUGAGGCCGUUAGGCCGAA IACUGCUA
15969





2616
GAAGGAGC A ACACACAG
6630
CUGUGUGU CUGAUGAGGCCGUUAGGCCGAA ICUCCUUC
15970





2619
GGAGCAAC A CACAGUGA
6631
UCACUGUG CUGAUGAGGCCGUUAGGCCGAA IUUGCUCC
15971





2621
AGCAACAC A CAGUGAGC
6632
GCUCACUG CUGAUGAGGCCGUUAGGCCGAA IUGUUGCU
15972





2623
CAACACAC A GUGAGCAU
6633
AUGCUCAC CUGAUGAGGCCGUUAGGCCGAA IUGUGUUG
15973





2630
CAGUGAGC A UCGAGCUC
6634
GAGCUCGA CUGAUGAGGCCGUUAGGCCGAA ICUCACUG
15974





2637
CAUCGAGC U CUCAUGUC
6635
GACAUGAG CUGAUGAGGCCGUUAGGCCGAA ICUCGAUG
15975





2639
UCGAGCUC U CAUGUCUG
6636
CAGACAUG CUGAUGAGGCCGUUAGGCCGAA IAGCUCGA
15976





2641
GAGCUCUC A UGUCUGAA
6637
UUCAGACA CUGAUGAGGCCGUUAGGCCGAA IAGAGCUC
15977





2646
CUCAUGUC U GAACUCAA
6638
UUGAGUUC CUGAUGAGGCCGUUAGGCCGAA IACAUGAG
15978





2651
GUCUGAAC U CAAGAUCC
6639
GGAUCUUG CUGAUGAGGCCGUUAGGCCGAA IUUCAGAC
15979





2653
CUGAACUC A AGAUCCUC
6640
GAGGAUCU CUGAUGAGGCCGUUAGGCCGAA IAGUUCAG
15980





2659
UCAAGAUC C UCAUUCAU
6641
AUGAAUGA CUGAUGAGGCCGUUAGGCCGAA IAUCUUGA
15981





2660
CAAGAUCC U CAUUCAUA
6642
UAUGAAUG CUGAUGAGGCCGUUAGGCCGAA IGAUCUUG
15982





2662
AGAUCCUC A UUCAUAUU
6643
AAUAUGAA CUGAUGAGGCCGUUAGGCCGAA IAGGAUCU
15983





2666
CCUCAUUC A UAUUGGUC
6644
GACCAAUA CUGAUGAGGCCGUUAGGCCGAA IAAUGAGG
15984





2675
UAUUGGUC A CCAUCUCA
6645
UGAGAUGG CUGAUGAGGCCGUUAGGCCGAA IACCAAUA
15985





2677
UUGGUCAC C AUCUCAAU
6646
AUUGAGAU CUGAUGAGGCCGUUAGGCCGAA IUGACCAA
15986





2678
UGGUCACC A UCUCAAUG
6647
CAGUGAGA CUGAUGAGGCCGUUAGGCCGAA IGUGACCA
15987





2681
UCACCAUC U CAAUGUGG
6648
CCACAUUG CUGAUGAGGCCGUUAGGCCGAA IAUGGUGA
15988





2683
ACCAUCUC A AUGUGGUC
6649
GACCACAU CUGAUGAGGCCGUUAGGCCGAA IAGAUGGU
15989





2692
AUGUGGUC A ACCUUCUA
6650
UAGAAGGU CUGAUGAGGCCGUUAGGCCGAA IACCACAU
15990





2695
UGGUCAAC C UUCUAGGU
6651
ACCUAGAA CUGAUGAGGCCGUUAGGCCGAA IUUGACCA
15991





2696
GGUCAACC U UCUAGGUG
6652
CACCUAGA CUGAUGAGGCCGUUAGGCCGAA IGUUGACC
15992





2699
CAACCUUC U AGGUGCCU
6653
AGGCACCU CUGAUGAGGCCGUUAGGCCGAA IAAGGUUG
15993





2706
CUAGGUGC C UGUACCAA
6654
UUGGUACA CUGAUGAGGCCGUUAGGCCGAA ICACCUAG
15994





2707
UAGGUGCC U GUACCAAG
6655
CUUGGUAC CUGAUGAGGCCGUUAGGCCGAA IGCACCUA
15995





2712
GCCUGUAC C AAGCCAGG
6656
CCUGGCUU CUGAUGAGGCCGUUAGGCCGAA IUACAGGC
15996





2713
CCUGUACC A AGCCAGGA
6657
UCCUGGCU CUGAUGAGGCCGUUAGGCCGAA IGUACAGG
15997





2717
UACCAAGC C AGGAGGGC
6658
GCCCUCCU CUGAUGAGGCCGUUAGGCCGAA ICUUGGUA
15998





2718
ACCAAGCC A GGAGGGCC
6659
GGCCCUCC CUGAUGAGGCCGUUAGGCCGAA IGCUUGGU
15999





2726
AGGAGGGC C ACUCAUGG
6660
CCAUGAGU CUGAUGAGGCCGUUAGGCCGAA ICCCUCCU
16000





2727
GGAGGGCC A CUCAUGGU
6661
ACCAUGAG CUGAUGAGGCCGUUAGGCCGAA IGCCCUCC
16001





2729
AGGGCCAC U CAUGGUGA
6662
UCACCAUG CUGAUGAGGCCGUUAGGCCGAA IUGGCCCU
16002





2731
GGCCACUC A UGGUGAUU
6663
AAUCACCA CUGAUGAGGCCGUUAGGCCGAA IAGUGGCC
16003





2749
UGGAAUUC U GCAAAUUU
6664
AAAUUUGC CUGAUGAGGCCGUUAGGCCGAA IAAUUCCA
16004





2752
AAUUCUGC A AAUUUGGA
6665
UCCAAAUU CUGAUGAGGCCGUUAGGCCGAA ICAGAAUU
16005





2764
UUGGAAAC C UGUCCACU
6666
AGUGGACA CUGAUGAGGCCGUUAGGCCGAA IUUUCCAA
16006





2765
UGGAAACC U GUCCACUU
6667
AAGUGGAC CUGAUGAGGCCGUUAGGCCGAA IGUUUCCA
16007





2769
AACCUGUC C ACUUACCU
6668
AGGUAAGU CUGAUGAGGCCGUUAGGCCGAA IACAGGUU
16008





2770
ACCUGUCC A CUUACCUG
6669
CAGGUAAG CUGAUGAGGCCGUUAGGCCGAA IGACAGGU
16009





2772
CUGUCCAC U UACCUGAG
6670
CUCAGGUA CUGAUGAGGCCGUUAGGCCGAA IUGGACAG
16010





2776
CCACUUAC C UGAGGAGC
6671
GCUCCUCA CUGAUGAGGCCGUUAGGCCGAA IUAAGUGG
16011





2777
CACUUACC U GAGGAGCA
6672
UGCUCCUC CUGAUGAGGCCGUUAGGCCGAA IGUAAGUG
16012





2785
UGAGGAGC A AGAGAAAU
6673
AUUUCUCU CUGAUGAGGCCGUUAGGCCGAA ICUCCUCA
16013





2803
AAUUUGUC C CCUACAAG
6674
CUUGUAGG CUGAUGAGGCCGUUAGGCCGAA IACAAAUU
16014





2804
AUUUGUCC C CUACAAGA
6675
UCUUGUAG CUGAUGAGGCCGUUAGGCCGAA IGACAAAU
16015





2805
UUUGUCCC C UACAAGAC
6676
GUCUUGUA CUGAUGAGGCCGUUAGGCCGAA IGGACAAA
16016





2806
UUGUCCCC U ACAAGACC
6677
GGUCUUGU CUGAUGAGGCCGUUAGGCCGAA IGGGACAA
16017





2809
UCCCCUAC A AGACCAAA
6678
UUUGGUCU CUGAUGAGGCCGUUAGGCCGAA IUAGGGGA
16018





2814
UACAAGAC C AAAGGGGC
6679
GCCCCUUU CUGAUGAGGCCGUUAGGCCGAA IUCUUGUA
16019





2815
ACAAGACC A AAGGGGCA
6680
UGCCCCUU CUGAUGAGGCCGUUAGGCCGAA IGUCUUGU
16020





2823
AAAGGGGC A CGAUUCCG
6681
CGGAAUCG CUGAUGAGGCCGUUAGGCCGAA ICCCCUUU
16021





2830
CACGAUUC C GUCAAGGG
6682
CCCUUGAC CUGAUGAGGCCGUUAGGCCGAA IAAUCGUG
16022





2834
AUUCCGUC A AGGGAAAG
6683
CUUUCCCU CUGAUGAGGCCGUUAGGCCGAA IACGGAAU
16023





2845
GGAAAGAC U ACGUUGGA
6684
UCCAACGU CUGAUGAGGCCGUUAGGCCGAA IUCUUUCC
16024





2856
GUUGGAGC A AUCCCUGU
6685
ACAGGGAU CUGAUGAGGCCGUUAGGCCGAA ICUCCAAC
16025





2860
GAGCAAUC C CUGUGGAU
6686
AUCCACAG CUGAUGAGGCCGUUAGGCCGAA IAUUGCUC
16026





2861
AGCAAUCC C UGUGGAUC
6687
GAUCCACA CUGAUGAGGCCGUUAGGCCGAA IGAUUGCU
16027





2862
GCAAUCCC U GUGGAUCU
6688
AGAUCCAC CUGAUGAGGCCGUUAGGCCGAA IGGAUUGC
16028





2870
UGUGGAUC U GAAACGGC
6689
GCCGUUUC CUGAUGAGGCCGUUAGGCCGAA IAUCCACA
16029





2881
AACGGCGC U UGGACAGC
6690
GCUGUCCA CUGAUGAGGCCGUUAGGCCGAA ICGCCGUU
16030





2887
GCUUGGAC A GCAUCACC
6691
GGUGAUGC CUGAUGAGGCCGUUAGGCCGAA IUCCAAGC
16031





2890
UGGACAGC A UCACCAGU
6692
ACUGGUGA CUGAUGAGGCCGUUAGGCCGAA ICUGUCCA
16032





2893
ACAGCAUC A CCAGUAGC
6693
GCUACUGG CUGAUGAGGCCGUUAGGCCGAA IAUGCUGU
16033





2895
AGCAUCAC C AGUAGCCA
6694
UGGCUACU CUGAUGAGGCCGUUAGGCCGAA IUGAUGCU
16034





2896
GCAUCACC A GUAGCCAG
6695
CUGGCUAC CUGAUGAGGCCGUUAGGCCGAA IGUGAUGC
16035





2902
CCAGUAGC C AGAGCUCA
6696
UGAGCUCU CUGAUGAGGCCGUUAGGCCGAA ICUACUGG
16036





2903
CAGUAGCC A GAGCUCAG
6697
CUGAGCUC CUGAUGAGGCCGUUAGGCCGAA IGCUACUG
16037





2908
GCCAGAGC U CAGCCAGC
6698
GCUGGCUG CUGAUGAGGCCGUUAGGCCGAA ICUCUGGC
16038





2910
CAGAGCUC A GCCAGCUC
6699
GAGCUGGC CUGAUGAGGCCGUUAGGCCGAA IAGCUCUG
16039





2913
AGCUCAGC C AGCUCUGG
6700
CCAGAGCU CUGAUGAGGCCGUUAGGCCGAA ICUGAGCU
16040





2914
GCUCAGCC A GCUCUGGA
6701
UCCAGAGO CUGAUGAGGCCGUUAGGCCGAA IGCUGAGC
16041





2917
CAGCCAGC U CUGGAUUU
6702
AAAUCCAG CUGAUGAGGCCGUUAGGCCGAA ICUGGCUG
16042





2919
GCCAGCUC U GGAUUUGU
6703
ACAAAUCC CUGAUGAGGCCGUUAGGCCGAA IAGCUGGC
16043





2940
GAGAAGUC C CUCAGUGA
6704
UCACUGAG CUGAUGAGGCCGUUAGGCCGAA IACUUCUC
16044





2941
AGAAGUCC C UCAGUGAU
6705
AUCACUGA CUGAUGAGGCCGUUAGGCCGAA IGACUUCU
16045





2942
GAAGUCCC U CAGUGAUG
6706
CAUCACUG CUGAUGAGGCCGUUAGGCCGAA IGGACUUC
16046





2944
AGUCCCUC A GUGAUGUA
6707
UACAUCAC CUGAUGAGGCCGUUAGGCCGAA IAGGGACU
16047





2967
GAGGAAGC U CCUGAAGA
6708
UCUUCAGO CUGAUGAGGCCGUUAGGCCGAA ICUUCCUC
16048





2969
GGAAGCUC C UGAAGAUC
6709
GAUCUUCA CUGAUGAGGCCGUUAGGCCGAA IAGCUUCC
16049





2970
GAAGCUCC U GAAGAUCU
6710
AGAUCUUC CUGAUGAGGCCGUUAGGCCGAA IGAGCUUC
16050





2978
UGAAGAUC U GUAUAAGG
6711
CCUUAUAC CUGAUGAGGCCGUUAGGCCGAA IAUCUUCA
16051





2989
AUAAGGAC U UCCUGACC
6712
GGUCAGGA CUGAUGAGGCCGUUAGGCCGAA IUCCUUAU
16052





2992
AGGACUUC C UGACCUUG
6713
CAAGGUCA CUGAUGAGGCCGUUAGGCCGAA IAAGUCCU
16053





2993
GGACUUCC U GACCUUGG
6714
CCAAGGUC CUGAUGAGGCCGUUAGGCCGAA IGAAGUCC
16054





2997
UUCCUGAC C UUGGAGCA
6715
UGCUCCAA CUGAUGAGGCCGUUAGGCCGAA IUCAGGAA
16055





2998
UCCUGACC U UGGAGCAU
6716
AUGCUCCA CUGAUGAGGCCGUUAGGCCGAA IGUCAGGA
16056





3005
CUUGGAGC A UCUCAUCU
6717
AGAUGAGA CUGAUGAGGCCGUUAGGCCGAA ICUCCAAG
16057





3008
GGAGCAUC U CAUCUGUU
6718
AACAGAUG CUGAUGAGGCCGUUAGGCCGAA IAUGCUCC
16058





3010
AGCAUCUC A UCUGUUAC
6719
GUAACAGA CUGAUGAGGCCGUUAGGCCGAA IAGAUGCU
16059





3013
AUCUCAUC U GUUACAGC
6720
GCUGUAAC CUGAUGAGGCCGUUAGGCCGAA IAUGAGAU
16060





3029
UCUGUUAC A GCUUCCAA
6721
UUGGAAGC CUGAUGAGGCCGUUAGGCCGAA IUAACAGA
16061





3022
GUUACAGC U UCCAAGUG
6722
CACUUGGA CUGAUGAGGCCGUUAGGCCGAA ICUGUAAC
16062





3025
ACAGCUUC C AAGUGGCU
6723
AGCCACUU CUGAUGAGGCCGUUAGGCCGAA IAAGCUGU
16063





3026
CAGCUUCC A AGUGGCUA
6724
UAGCCACU CUGAUGAGGCCGUUAGGCCGAA IGAAGCUG
16064





3033
CAAGUGGC U AAGGGCAU
6725
AUGCCCUU CUGAUGAGGCCGUUAGGCCGAA ICCACUUG
16065





3040
CUAAGGGC A UGGAGUUC
6726
GAACUCCA CUGAUGAGGCCGUUAGGCCGAA ICCCUUAG
16066





3049
UGGAGUUC U UGGCAUCG
6727
CGAUGCCA CUGAUGAGGCCGUUAGGCCGAA IAACUCCA
16067





3054
UUCUUGGC A UCGCGAAA
6728
UUUCGCGA CUGAUGAGGCCGUUAGGCCGAA ICCAAGAA
16068





3070
AGUGUAUC C ACAGGGAC
6729
GUCCCUGU CUGAUGAGGCCGUUAGGCCGAA IAUACACU
16069





3071
GUGUAUCC A CAGGGACC
6730
GGUCCCUG CUGAUGAGGCCGUUAGGCCGAA IGAUACAC
16070





3073
GUAUCCAC A GGGACCUG
6731
CAGGUCCC CUGAUGAGGCCGUUAGGCCGAA IUGGAUAC
16071





3079
ACAGGGAC C UGGCGGCA
6732
UGCCGCCA CUGAUGAGGCCGUUAGGCCGAA IUCCCUGU
16072





3080
CAGGGACC U GGCGGCAC
6733
GUGCCGCC CUGAUGAGGCCGUUAGGCCGAA IGUCCCUG
16073





3087
CUGGCGGC A CGAAAUAU
6734
AUAUUUCG CUGAUGAGGCCGUUAGGCCGAA ICCGCCAG
16074





3097
GAAAUAUC C UCUUAUCG
6735
CGAUAAGA CUGAUGAGGCCGUUAGGCCGAA IAUAUUUC
16075





3098
AAAUAUCC U CUUAUCGG
6736
CCGAUAAG CUGAUGAGGCCGUUAGGCCGAA IGAUAUUU
16076





3100
AUAUCCUC U UAUCGGAG
6737
CUCCGAUA CUGAUGAGGCCGUUAGGCCGAA IAGGAUAU
16077





3127
UUAAAAUC U GUGACUUU
6738
AAAGUCAC CUGAUGAGGCCGUUAGGCCGAA IAUUUUAA
16078





3133
UCUGUGAC U UUGGCUUG
6739
CAAGCCAA CUGAUGAGGCCGUUAGGCCGAA IUCACAGA
16079





3139
ACUUUGGC U UGGCCCGG
6740
CCGGGCCA CUGAUGAGGCCGUUAGGCCGAA ICCAAAGU
16080





3144
GGCUUGGC C CCGGAUAU
6741
AUAUCCCG CUGAUGAGGCCGUUAGGCCGAA ICCAAGCC
16081





3145
GCUUGGCC C GGGAUAUU
6742
AAUAUCCC CUGAUGAGGCCGUUAGGCCGAA IGCCAAGC
16082





3164
UAAAGAUC C AGAUUAUG
6743
CAUAAUCU CUGAUGAGGCCGUUAGGCCGAA IAUCUUUA
16083





3165
AAAGAUCC A GAUUAUGU
6744
ACAUAAUC CUGAUGAGGCCGUUAGGCCGAA IGAUCUUU
16084





3175
AUUAUGUC A GAAAAGGA
6745
UCCUUUUC CUGAUGAGGCCGUUAGGCCGAA IACAUAAU
16085





3189
GGAGAUGC U CGCCUCCC
6746
GGGAGGCG CUGAUGAGGCCGUUAGGCCGAA ICAUCUCC
16086





3293
AUGCUCGC C UCCCUUUG
6747
CAAAGGGA CUGAUGAGGCCGUUAGGCCGAA ICGAGCAU
16087





3294
UGCUCGCC U CCCUUUGA
6748
UCAAAGGG CUGAUGAGGCCGUUAGGCCGAA IGCGAGCA
16088





3296
CUCGCCUC C CUUUGAAA
6749
UUUCAAAG CUGAUGAGGCCGUUAGGCCGAA IAGGCGAG
16089





3297
UCGCCUCC C UUUGAAAU
6750
AUUUCAAA CUGAUGAGGCCGUUAGGCCGAA IGAGGCGA
16090





3298
CGCCUCCC U UUGAAAUG
6751
CAUUUCAA CUGAUGAGGCCGUUAGGCCGAA IGGAGGCG
16091





3213
UGGAUGGC C CCAGAAAC
6752
CUUUCUGG CUGAUGAGGCCGUUAGGCCGAA ICCAUCCA
16092





3214
GGAUGGCC C CAGAAACA
6753
UGUUUCUG CUGAUGAGGCCGUUAGGCCGAA IGCCAUCC
16093





3215
GAUGGCCC C AGAAACAA
6754
UUGUUUCU CUGAUGAGGCCGUUAGGCCGAA IGGCCAUC
16094





3216
AUGGCCCC A GAAACAAU
6755
AUUGUUUC CUGAUGAGGCCGUUAGGCCGAA IGCGCCAU
16095





3222
CCAGAAAC A AUUUUUGA
6756
UCAAAAAU CUGAUGAGGCCGUUAGGCCGAA IUUUCUGG
16096





3232
UUUUUGAC A GAGUGUAC
6757
GUACACUC CUGAUGAGGCCGUUAGGCCGAA IUCAAAAA
16097





3241
GAGUGUAC A CAAUCCAG
6758
CUGGAUUG CUGAUGAGGCCGUUAGGCCGAA IUACACUC
16098





3243
GUGUACAC A AUCCAGAG
6759
CUCUGGAU CUGAUGAGGCCGUUAGGCCGAA IUGUACAC
16099





3247
ACACAAUC C AGAGUGAC
6760
GUCACUCU CUGAUGAGGCCGUUAGGCCGAA IAUUGUGU
16100





3248
CACAAUCC A GAGUGACG
6761
CGUCACUC CUGAUGAGGCCGUUAGGCCGAA IGAUUGUG
16101





3259
GUGACGUC U GGUCUUUU
6762
AAAAGACC CUGAUGAGGCCGUUAGGCCGAA IACGUCAC
16102





3264
GUCUGGUC U UUUGGUGU
6763
ACACCAAA CUGAUGAGGCCGUUAGGCCGAA IACCAGAC
16103





3278
UGUUUUGC U GUGGGAAA
6764
UUUCCCAC CUGAUGAGGCCGUUAGGCCGAA ICAAAACA
16104





3294
AUAUUUUC C UUAGGUGC
6765
GCACCUAA CUGAUGAGGCCGUUAGGCCGAA IAAAAUAU
16105





3295
UAUUUUCC U UAGGUGCU
6766
AGCACCUA CUGAUGAGGCCGUUAGGCCGAA IGAAAAUA
16106





3303
UUAGGUGC U UCUCCAUA
6767
UAUGGAGA CUGAUGAGGCCGUUAGGCCGAA ICACCUAA
16107





3306
GGUGCUUC U CCAUAUCC
6768
GGAUAUGG CUGAUGAGGCCGUUAGGCCGAA IAAGCACC
16108





3308
UGCUUCUC C AUAUCCUG
6769
CAGGAUAU CUGAUGAGGCCGUUAGGCCGAA IAGAAGCA
16109





3309
GCUUCUCC A UAUCCUGG
6770
CCAGGAUA CUGAUGAGGCCGUUAGGCCGAA IGAGAAGC
16110





3314
UCCAUAUC C UGGGGUAA
6771
UUACCCCA CUGAUGAGGCCGUUAGGCCGAA IAUAUGGA
16111





3315
CCAUAUCC U GGGGUAAA
6772
UUUACCCC CUGAUGAGGCCGUUAGGCCGAA IGAUAUGG
16112





3363
GAAGGAAC U AGAAUGAG
6773
CUCAUUCU CUGAUGAGGCCGUUAGGCCGAA IUUCCUUC
16113





3375
AUGAGGGC C CCUGAUUA
6774
UAAUCAGG CUGAUGAGGCCGUUAGGCCGAA ICCCUCAU
16114





3376
UGAGGGCC C CUGAUUAU
6775
AUAAUCAG CUGAUGAGGCCGUUAGGCCGAA IGCCCUCA
16115





3377
GAGGGCCC C UGAUUAUA
6776
UAUAAUCA CUGAUGAGGCCGUUAGGCCGAA IGGCCCUC
16116





3378
AGGGCCCC U GAUUAUAC
6777
GUAUAAUC CUGAUGAGGCCGUUAGGCCGAA IGGGCCCU
16117





3387
GAUUAUAC U ACACCAGA
6778
UCUGGUGU CUGAUGAGGCCGUUAGGCCGAA IUAUAAUC
16118





3390
UAUACUAC A CCAGAAAU
6779
AUUUCUGG CUGAUGAGGCCGUUAGGCCGAA IUAGUAUA
16119





3392
UACUACAC C AGAAAUGU
6780
ACAUUUCU CUGAUGAGGCCGUUAGGCCGAA IUGUAGUA
16120





3393
ACUACACC A GAAAUGUA
6781
UACAUUUC CUGAUGAGGCCGUUAGGCCGAA IGUGUAGU
16121





3403
AAAUGUAC C AGACCAUG
6782
CAUGGUCU CUGAUGAGGCCGUUAGGCCGAA IUACAUUU
16122





3404
AAUGUACC A GACCAUGC
6783
GCAUGGUC CUGAUGAGGCCGUUAGGCCGAA IGUACAUU
16123





3408
UACCAGAC C AUGCUGGA
6784
UCCAGCAU CUGAUGAGGCCGUUAGGCCGAA IUCUGGUA
16124





3409
ACCAGACC A UGCUGGAC
6785
GUCCAGCA CUGAUGAGGCCGUUAGGCCGAA IGUCUGGU
16125





3413
GACCAUGC U GGACUGCU
6786
AGCAGUCC CUGAUGAGGCCGUUAGGCCGAA ICAUGGUC
16126





3418
UGCUGGAC U GCUGGCAC
4886
GUGCCAGC CUGAUGAGGCCGUUAGGCCGAA IUCCAGCA
14226





3421
UGGACUGC U GGCACGGG
6787
CCCGUGCC CUGAUGAGGCCGUUAGGCCGAA ICAGUCCA
16127





3425
CUGCUGGC A CGGGGAGC
6788
GCUCCCCG CUGAUGAGGCCGUUAGGCCGAA ICCAGCAG
16128





3434
CGGGGAGC C CAGUCAGA
6789
UCUGACUG CUGAUGAGGCCGUUAGGCCGAA ICUCCCCG
16129





3435
GGGGAGCC C AGUCAGAG
6790
CUCUGACU CUGAUGAGGCCGUUAGGCCGAA IGCUCCCC
16130





3436
GGGAGCCC A GUCAGAGA
6791
UCUCUGAC CUGAUGAGGCCGUUAGGCCGAA IGGCUCCC
16131





3440
GCCCAGUC A GAGACCCA
6792
UGGGUCUC CUGAUGAGGCCGUUAGGCCGAA IACUGGGC
16132





3446
UCAGAGAC C CACGUUUU
6793
AAAACGUG CUGAUGAGGCCGUUAGGCCGAA IUCUCUGA
16133





3447
CAGAGACC C ACGUUUUC
6794
GAAAACGU CUGAUGAGGCCGUUAGGCCGAA IGUCUCUG
16134





3448
AGAGACCC A CGUUUUCA
6795
UGAAAACG CUGAUGAGGCCGUUAGGCCGAA IGGUCUCU
16135





3456
ACGUUUUC A GAGUUGGU
6796
ACCAACUC CUGAUGAGGCCGUUAGGCCGAA IAAAACGU
16136





3470
GGUGGAAC A UUUGGGAA
6797
UUCCCAAA CUGAUGAGGCCGUUAGGCCGAA IUUCCACC
16137





3482
GGGAAAUC U CUUGCAAG
6798
CUUGCAAG CUGAUGAGGCCGUUAGGCCGAA IAUUUCCC
16138





3484
GAAAUCUC U UGCAAGCU
6799
AGCUUGCA CUGAUGAGGCCGUUAGGCCGAA IAGAUUUC
16139





3488
UCUCUUGC A AGCUAAUG
6800
CAUUAGCU CUGAUGAGGCCGUUAGGCCGAA ICAAGAGA
16140





3492
UUGCAAGC U AAUGCUCA
6801
UGAGCAUU CUGAUGAGGCCGUUAGGCCGAA ICUUGCAA
16141





3498
GCUAAUGC U CAGCAGGA
6802
UCCUGCUG CUGAUGAGGCCGUUAGGCCGAA ICAUUAGC
16142





3500
UAAUGCUC A GCAGGAUG
6803
CAUCCUGC CUGAUGAGGCCGUUAGGCCGAA IAGCAUUA
16143





3503
UGCUCAGC A GGAUGGCA
6804
UGCCAUCC CUGAUGAGGCCGUUAGGCCGAA ICUGAGCA
16144





3511
AGGAUGGC A AAGACUAC
6805
GUAGUCUU CUGAUGAGGCCGUUAGGCCGAA ICCAUCCU
16145





3517
GCAAAGAC U ACAUUGUU
6806
AACAAUGU CUGAUGAGGCCGUUAGGCCGAA IUCUUUGC
16146





3520
AAGACUAC A UUGUUCUU
6807
AAGAACAA CUGAUGAGGCCGUUAGGCCGAA IUAGUCUU
16147





3527
CAUUGUUC U UCCGAUAU
6808
AUAUCGGA CUGAUGAGGCCGUUAGGCCGAA IAACAAUG
16148





3530
UGUUCUUC C GAUAUCAG
6809
CUGAUAUC CUGAUGAGGCCGUUAGGCCGAA IAAGAACA
16149





3537
CCGAUAUC A GAGACUUU
6810
AAAGUCUC CUGAUGAGGCCGUUAGGCCGAA IAUAUCGG
16150





3543
UCAGAGAC U UUGAGCAU
6811
AUGCUCAA CUGAUGAGGCCGUUAGGCCGAA IUCUCUGA
16151





3550
CUUUGAGC A UGGAAGAG
6812
CUCUUCCA CUGAUGAGGCCGUUAGGCCGAA ICUCAAAG
16152





3564
GAGGAUUC U GUACUCUC
6813
GAGAGUCC CUGAUGAGGCCGUUAGGCCGAA IAAUCCUC
16153





3569
UUCUGGAC U CUCUCUGC
6814
GCAGAGAG CUGAUGAGGCCGUUAGGCCGAA IUCCAGAA
16154





3571
CUGGACUC U CUCUGCCU
6815
AGGCAGAG CUGAUGAGGCCGUUAGGCCGAA IAGUCCAG
16155





3573
GGACUCUC U CUGCCUAC
6816
GUAGGCAG CUGAUGAGGCCGUUAGGCCGAA IAGAGUCC
16156





3575
ACUCUCUC U GCCUACCU
6817
AGGUAGGC CUGAUGAGGCCGUUAGGCCGAA IAGAGAGU
16157





3578
CUCUCUGC C UACCUCAC
6818
GUGAGGUA CUGAUGAGGCCGUUAGGCCGAA ICAGAGAG
16158





3579
UCUCUGCC U ACCUCACC
6819
GGUGAGGU CUGAUGAGGCCGUUAGGCCGAA IGCAGAGA
16159





3582
CUGCCUAC C UCACCUGU
6820
ACAGGUGA CUGAUGAGGCCGUUAGGCCGAA IUAGGCAG
16160





3583
UGCCUACC U CACCUGUU
6821
AACAGGUG CUGAUGAGGCCGUUAGGCCGAA IGUAGGCA
16161





3585
CCUACCUC A CCUGUUUC
6822
GAAACAGG CUGAUGAGGCCGUUAGGCCGAA IAGGUAGG
16162





3587
UACCUCAC C UGUUUCCU
6823
AGGAAACA CUGAUGAGGCCGUUAGGCCGAA IUGAGGUA
16163





3588
ACCUCACC U GUUUCCUG
6824
CAGGAAAC CUGAUGAGGCCGUUAGGCCGAA IGUGAGGU
16164





3594
CCUGUiUC C UGUAUGGA
6825
UCCAUACA CUGAUGAGGCCGUUAGGCCGAA IAAACAGG
16165





3595
CUGUUUCC U GUAUGGAG
6826
CUCCAUAC CUGAUGAGGCCGUUAGGCCGAA IGAAACAG
16166





3622
UAUGUGAC C CCAAAUUC
6827
GAAUUUGG CUGAUGAGGCCGUUAGGCCGAA IUCACAUA
16167





3623
AUGUGACC C CAAAUUCC
6828
GGAAUUUG CUGAUGAGGCCGUUAGGCCGAA IGUCACAU
16168





3624
UGUGACCC C AAAUUCCA
6829
UGGAAUUU CUGAUGAGGCCGUUAGGCCGAA IGGUCACA
16169





3625
GUGACCCC A AAUUCCAU
6830
AUGGAAUU CUGAUGAGGCCGUUAGGCCGAA IGGGUCAC
16170





3631
CCAAAUUC C AUUAUGAC
6831
GUCAUAAU CUGAUGAGGCCGUUAGGCCGAA IAAUUUGG
16171





3632
CAAAUUCC A UUAUGACA
6832
UGUCAUAA CUGAUGAGGCCGUUAGGCCGAA IGAAUUUG
16172





3640
AUUAUGAC A ACACAGCA
6833
UGCUGUGU CUGAUGAGGCCGUUAGGCCGAA IUCAUAAU
16173





3643
AUGACAAC A CAGCAGGA
6834
UCCUGCUG CUGAUGAGGCCGUUAGGCCGAA IUUGUCAU
16174





3645
GACAACAC A GCAGGAAU
6835
AUUCCUGC CUGAUGAGGCCGUUAGGCCGAA IUGUUGUC
16175





3648
AACACAGC A GGAAUCAG
6836
CUGAUUCC CUGAUGAGGCCGUUAGGCCGAA ICUGUGUU
16176





3655
CAGGAAUC A GUCAGUAU
6837
AUACUGAC CUGAUGAGGCCGUUAGGCCGAA IAUUCCUG
16177





3659
AAUCAGUC A GUAUCUGC
6838
GCAGAUAC CUGAUGAGGCCGUUAGGCCGAA IACUGAUU
16178





3665
UCAGUAUC U GCAGAACA
6839
UGUUCUGC CUGAUGAGGCCGUUAGGCCGAA IAUACUGA
16179





3668
GUAUCUGC A GAACAGUA
6840
UACUGUUC CUGAUGAGGCCGUUAGGCCGAA ICAGAUAC
16180





3673
UGCAGAAC A GUAAGCGA
6841
UCGCUUAC CUGAUGAGGCCGUUAGGCCGAA IUUCUGCA
16181





3688
GAAAGAGC C GGCCUGUG
6842
CACAGGCC CUGAUGAGGCCGUUAGGCCGAA ICUCUUUC
16182





3692
GAGCCGGC C UGUGAGUG
6843
CACUCACA CUGAUGAGGCCGUUAGGCCGAA ICCGGCUC
16183





3693
AGCCGGCC U GUGAGUGU
6844
ACACUCAC CUGAUGAGGCCGUUAGGCCGAA IGCCGGCU
16184





3708
GUAAAAAC A UUUGAAGA
6845
UCUUCAAA CUGAUGAGGCCGUUAGGCCGAA IUUUUUAC
16185





3721
AAGAUAUC C CCUUAGAA
6846
UUCUAACG CUGAUGAGGCCGUUAGGCCGAA IAUAUCUU
16186





3722
AGAUAUCC C GUUAGAAG
6847
CUUCUAAC CUGAUGAGGCCGUUAGGCCGAA IGAUAUCU
16187





3734
AGAAGAAC C AGAAGUAA
6848
UUACUUCU CUGAUGAGGCCGUUAGGCCGAA IUUCUUCU
16188





3735
GAAGAACC A GAAGUAAA
6849
UUUACUUC CUGAUGAGGCCGUUAGGCCGAA IGUUCUUC
16189





3751
AAGUAAUC C CAGAUGAC
6850
GUCAUCUG CUGAUGAGGCCGUUAGGCCGAA IAUUACUU
16190





3752
AGUAAUCC C AGAUGACA
6851
UGUCAUCU CUGAUGAGGCCGUUAGGCCGAA IGAUUACU
16191





3753
GUAAUCCC A GAUGACAA
6852
UUGUCAUC CUGAUGAGGCCGUUAGGCCGAA IGGAUUAC
16192





3760
CAGAUGAC A ACCAGACG
6853
CGUCUGGU CUGAUGAGGCCGUUAGGCCGAA IUCAUCUG
16193





3763
AUGACAAC C AGACGGAC
6854
GUCCGUCU CUGAUGAGGCCGUUAGGCCGAA IUUGUCAU
16194





3764
UGACAACC A GACGGACA
6855
UGUCCGUC CUGAUGAGGCCGUUAGGCCGAA IGUUGUCA
16195





3772
AGACGGAC A GUGGUAUG
6856
CAUACCAC CUGAUGAGGCCGUUAGGCCGAA IUCCGUCU
16196





3785
UAUGGUUC U UGCCUCAG
6857
CUGAGGCA CUGAUGAGGCCGUUAGGCCGAA IAACCAUA
16197





3789
GUUCUUGC C UCAGAAGA
6858
UCUUCUGA CUGAUGAGGCCGUUAGGCCGAA ICAAGAAC
16198





3790
UUCUUGCC U CAGAAGAG
6859
CUCCUCUG CUGAUGAGGCCGUUAGGCCGAA IGCAAGAA
16199





3792
CUUGCCUC A GAAGAGCU
6860
AGCUCUUC CUGAUGAGGCCGUUAGGCCGAA IAGGCAAG
16200





3800
AGAAGAGC U GAAAACUU
6861
AAGUUUUC CUGAUGAGGCCGUUAGGCCGAA ICUCUUCU
16201





3807
CUGAAAAC U UUGGAAGA
6862
UCUUCCAA CUGAUGAGGCCGUUAGGCCGAA IUUUUCAG
16202





3817
UGGAAGAC A GAACCAAA
6863
UUUGGUUC CUGAUGAGGCCGUUAGGCCGAA IUCUUCCA
16203





3822
GACAGAAC C AAAUUAUC
6864
GAUAAUUU CUGAUGAGGCCGUUAGGCCGAA IUUCUGUC
16204





3823
ACAGAACC A AAUUAUCU
6865
AGAUAAUU CUGAUGAGGCCGUUAGGCCGAA IGUUCUGU
16205





3831
AAAUUAUC U CCAUCUUU
6866
AAAGAUGG CUGAUGAGGCCGUUAGGCCGAA IAUAAUUU
16206





3833
AUUAUCUC C AUCUUUUG
6867
CAAAAGAU CUGAUGAGGCCGUUAGGCCGAA IAGAUAAU
16207





3834
UUAUCUCC A UCUUUUGG
6868
CCAAAAGA CUGAUGAGGCCGUUAGGCCGAA IGAGAUAA
16208





3837
UCUCCAUC U UUUGGUGG
6869
CCACCAAA CUGAUGAGGCCGUUAGGCCGAA IAUGGAGA
16209





3854
AAUGGUGC C CAGCAAAA
6870
UUUUGCUG CUGAUGAGGCCGUUAGGCCGAA ICACCAUU
16210





3855
AUGGUGCC C AGCAAAAG
6871
CUUUUGCU CUGAUGAGGCCGUUAGGCCGAA IGCACCAU
16211





3856
UGGUGCCC A GCAAAAGC
6872
GCUUUUGC CUGAUGAGGCCGUUAGGCCGAA IGGCACCA
16212





3859
UGCCCAGC A AAAGCAGG
6873
CCUGCUUU CUGAUGAGGCCGUUAGGCCGAA ICUGGGCA
16213





3865
GCAAAAGC A GGGAGUCU
6874
AGACUCCC CUGAUGAGGCCGUUAGGCCGAA ICU(UUGC
16214





3873
AGGGAGUC U GUGGCAUC
6875
GAUGCCAC CUGAUGAGGCCGUUAGGCCGAA IACUCCCU
16215





3879
UCUGUGGC A UCUGAAGG
6876
CCUUCAGA CUGAUGAGGCCGUUAGGCCGAA ICCACAGA
16216





3882
GUGGCAUC U GAAGGCUC
6877
GAGCCUUC CUGAUGAGGCCGUUAGGCCGAA IAUGCCAC
16217





3889
CUGAAGGC U CAAACCAG
6878
CUGGUUUG CUGAUGAGGCCGUUAGGCCGAA ICCUUCAG
16218





3891
GAAGGCUC A AACCAGAC
6879
GUCUGGUU CUGAUGAGGCCGUUAGGCCGAA IAGCCUUC
16219





3895
GCUCAAAC C AGACAAGC
6880
GCUUGUCU CUGAUGAGGCCGUUAGGCCGAA IUUUGAGC
16220





3896
CUCAAACC A GACAAGCG
6881
CGCUUGUC CUGAUGAGGCCGUUAGGCCGAA IGUUUGAG
16221





3900
AACCAGAC A AGCGGCUA
6882
UAGCCGCU CUGAUGAGGCCGUUAGGCCGAA IUCUGGUU
16222





3907
CAAGCGGC U ACCAGUCC
6883
GGACUGGU CUGAUGAGGCCGUUAGGCCGAA ICCGCUUG
16223





3910
GCGGCUAC C AGUCCGGA
6884
UCCGGACU CUGAUGAGGCCGUUAGGCCGAA IUAGCCGC
16224





3911
CGGCUACC A GUCCGGAU
6885
AUCCGGAC CUGAUGAGGCCGUUAGGCCGAA IGUAGCCG
16225





3915
UACCAGUC C GGAUAUCA
6886
UGAUAUCC CUGAUGAGGCCGUUAGGCCGAA IACUGGUA
16226





3923
CGGAUAUC A CUCCGAUG
6887
CAUCGGAG CUGAUGAGGCCGUUAGGCCGAA IAUAUCCG
16227





3925
GAUAUCAC U CCGAUGAC
6888
GUCAUCGG CUGAUGAGGCCGUUAGGCCGAA IUGAUAUC
16228





3927
UAUCACUC C GAUGACAC
6889
GUGUCAUC CUGAUGAGGCCGUUAGGCCGAA IAGUGAUA
16229





3934
CCGAUGAC A CAGACACC
6890
GGUGUCUG CUGAUGAGGCCGUUAGGCCGAA IUCAUCGG
16230





3936
GAUGACAC A GACACCAC
6891
GUGGUGUC CUGAUGAGGCCGUUAGGCCGAA IUGUCAUC
16231





3940
ACACAGAC A CCACCGUG
6892
CACGGUGG CUGAUGAGGCCGUUAGGCCGAA IUCUGUGU
16232





3942
ACAGACAC C ACCGUGUA
6893
UACACGGU CUGAUGAGGCCGUUAGGCCGAA IUGUCUGU
16233





3943
CAGACACC A CCGUGUAC
6894
GUACACGG CUGAUGAGGCCGUUAGGCCGAA IGUGUCUG
16234





3945
GACACCAC C GUGUACUC
6895
GAGUACAC CUGAUGAGGCCGUUAGGCCGAA IUGGUGUC
16235





3952
CCGUGUAC U CCAGUGAG
6896
CUCACUGG CUGAUGAGGCCGUUAGGCCGAA IUACACGG
16236





3954
GUGUACUC C AGUGAGGA
6897
UCCUCACU CUGAUGAGGCCGUUAGGCCGAA IAGUACAC
16237





3955
UGUACUCC A GUGAGGAA
6898
UUCCUCAC CUGAUGAGGCCGUUAGGCCGAA IGAGUACA
16238





3966
GAGGAAGC A GAACUUUU
6899
AAAAGUUC CUGAUGAGGCCGUUAGGCCGAA ICUUCCUC
16239





3971
AGCAGAAC U UUUAAAGC
6900
GCUUUAAA CUGAUGAGGCCGUUAGGCCGAA IUUCUGCU
16240





3980
UUUAAAGC U GAUAGAGA
6901
UCUCUAUC CUGAUGAGGCCGUUAGGCCGAA ICUUUAAA
16241





3998
UGGAGUGC A AACCGGUA
6902
UACCGGUU CUGAUGAGGCCGUUAGGCCGAA ICACUCCA
16242





4002
GUGCAAAC C GGUAGCAC
6903
GUGCUACC CUGAUGAGGCCGUUAGGCCGAA IUUUGCAC
16243





4009
CCGGUAGC A CAGCCCAG
6904
CUGGGCUG CUGAUGAGGCCGUUAGGCCGAA ICUACCGG
16244





4011
GGUAGCAC A GCCCAGAU
6905
AUCUGGGC CUGAUGAGGCCGUUAGGCCGAA IUGCUACC
16245





4014
AGCACAGC C CAGAUUCU
6906
AGAAUCUG CUGAUGAGGCCGUUAGGCCGAA ICUGUGCU
16246





4015
GCACAGCC C AGAUUCUC
6907
GAGAAUCU CUGAUGAGGCCGUUAGGCCGAA IGCUGUGC
16247





4016
CACAGCCC A GAUUCUCC
6908
GGAGAAUC CUGAUGAGGCCGUUAGGCCGAA IGGCUGUG
16248





4022
CCAGAUUC U CCAGCCUG
6909
CAGGCUGG CUGAUGAGGCCGUUAGGCCGAA IAAUCUGG
16249





4024
AGAUUCUC C AGCCUGAC
6910
GUCAGGCU CUGAUGAGGCCGUUAGGCCGAA IAGAAUCU
16250





4025
GAUUCUCC A GCCUGACA
6911
UGUCAGGC CUGAUGAGGCCGUUAGGCCGAA IGAGAAUC
16251





4028
UCUCCAGC C UGACACGG
6912
CCGUGUCA CUGAUGAGGCCGUUAGGCCGAA ICUGGAGA
16252





4029
CUCCAGCC U GACACGGG
6913
CCCGUGUC CUGAUGAGGCCGUUAGGCCGAA IGCUGGAG
16253





4033
AGCCUGAC A CGGGGACC
6914
GGUCCCCG CUGAUGAGGCCGUUAGGCCGAA IUCAGGCU
16254





4041
ACGGGGAC C ACACUGAG
6915
CUCAGUGU CUGAUGAGGCCGUUAGGCCGAA IUCCCCGU
16255





4042
CGGGGACC A CACUGAGC
6916
GCUCAGUG CUGAUGAGGCCGUUAGGCCGAA IGUCCCCG
16256





4044
GGGACCAC A CUGAGCUC
6917
GAGCUCAG CUGAUGAGGCCGUUAGGCCGAA IUGGUCCC
16257





4046
GACCACAC U GAGCUCUC
6918
GAGAGCUC CUGAUGAGGCCGUUAGGCCGAA IUGUGGUC
16258





4051
CACUGAGC U CUCCUCCU
6919
AGGAGGAG CUGAUGAGGCCGUUAGGCCGAA ICUCAGUG
16259





4053
CUGAGCUC U CCUCCUGU
6920
ACAGGAGG CUGAUGAGGCCGUUAGGCCGAA IAGOUCAG
16260





4055
GAGCUCUC C UCCUGUUU
6921
AAACAGGA CUGAUGAGGCCGUUAGGCCGAA IAGAGCUC
16261





4056
AGCUCUCC U CCUGUUUA
6922
UAAACAGG CUGAUGAGGCCGUUAGGCCGAA IGAGAGCU
16262





4058
CUCUCCUC C UGUUUAAA
6923
UUUAAACA CUGAUGAGGCCGUUAGGCCGAA IAGGAGAG
16263





4059
UCUCCUCC U GUUUAAAA
6924
UUUUAAAC CUGAUGAGGCCGUUAGGCCGAA IGAGGAGA
16264





4074
AAGGAAGC A UCCACACC
6925
GGUGUGGA CUGAUGAGGCCGUUAGGCCGAA ICUUCCUU
16265





4077
GAAGCAUC C ACACCCCA
6926
UGGGGUGU CUGAUGAGGCCGUUAGGCCGAA IAUGCUUC
16266





4078
AAGCAUCC A CACCCCAA
6927
UUGGGGUG CUGAUGAGGCCGUUAGGCCGAA IGAUGCUU
16267





4080
GCAUCCAC A CCCCAACU
6928
AGUUGGGG CUGAUGAGGCCGUUAGGCCGAA IUGGAUGC
16268





4082
AUCCACAC C CCAACUCC
6929
GGAGUUGG CUGAUGAGGCCGUUAGGCCGAA IUGUGGAU
16269





4083
UCCACACC C CAACUCCC
6930
GGGAGUUG CUGAUGAGGCCGUUAGGCCGAA IGUGUGGA
16270





4084
CCACACCC C AACUCCCG
6931
CGGGAGUU CUGAUGAGGCCGUUAGGCCGAA IGGUGUGG
16271





4085
CACACCCC A ACUCCCGG
6932
CCGGGAGU CUGAUGAGGCCGUUAGGCCGAA IGGGUGUG
16272





4088
ACCCCAAC U CCCGGACA
6933
UGUCCGGG CUGAUGAGGCCGUUAGGCCGAA IUUGGGGU
16273





4090
CCCAACUC C CCGACAUC
6934
GAUGUCCG CUGAUGAGGCCGUUAGGCCGAA IAGUUGGG
16274





4091
CCAACUCC C GGACAUCA
6935
UGAUGUCC CUGAUGAGGCCGUUAGGCCGAA IGAGUUGG
16275





4096
UCCCGGAC A UCACAUGA
6936
UCAUGUGA CUGAUGAGGCCGUUAGGCCGAA IUCCGGGA
16276





4099
CGGACAUC A CAUGAGAG
6937
CUCUCAUG CUGAUGAGGCCGUUAGGCCGAA IAUGUCCG
16277





4101
GACAUCAC A UGAGAGGU
6938
ACCUCUCA CUGAUGAGGCCGUUAGGCCGAA IUGAUGUC
16278





4111
GAGAGGUC U GCUCAGAU
6939
AUCUGAGC CUGAUGAGGCCGUUAGGCCGAA IACCUCUC
16279





4114
AGGUCUGC U CAGAUUUU
6940
AAAAUCUG CUGAUGAGGCCGUUAGGCCGAA ICAGACCU
16280





4116
GUCUGCUC A GAUUUUGA
6941
UCAAAAUC CUGAUGAGGCCGUUAGGCCGAA IAGCAGAC
16281





4135
UGUUGUUC U UUCCACCA
6942
UGGUGGAA CUGAUGAGGCCGUUAGGCCGAA IAACAACA
16282





4139
GUUCUUUC C ACCAGCAG
6943
CUGCUGGU CUGAUGAGGCCGUUAGGCCGAA IAAAGAAC
16283





4140
UUCUUUCC A CCAGCAGG
6944
CCUGCUGG CUGAUGAGGCCGUUAGGCCGAA IGAAAGAA
16284





4142
CUUUCCAC C AGCAGGAA
6945
UUCCUGCU CUGAUGAGGCCGUUAGGCCGAA IUGGAAAG
16285





4143
UUUCCACC A GCAGGAAG
6946
CUUCCUGC CUGAUGAGGCCGUUAGGCCGAA IGUGGAAA
16286





4146
CCACCAGC A GGAAGUAG
6947
CUACUUCC CUGAUGAGGCCGUUAGGCCGAA ICUGGUGG
16287





4156
GAAGUAGC C CCAUUUGA
6948
UCAAAUGC CUGAUGAGGCCGUUAGGCCGAA ICUACUUC
16288





4159
GUAGCCGC A UUUGAUUU
6949
AAAUCAAA CUGAUGAGGCCGUUAGGCCGAA ICGGCUAC
16289





4170
UGAUUUUC A UUUCGACA
6950
UGUCGAAA CUGAUGAGGCCGUUAGGCCGAA IAAAAUCA
16290





4178
AUUUCGAC A ACAGAAAA
6951
UUUUCUGU CUGAUGAGGCCGUUAGGCCGAA IUCGAAAU
16291





4181
UCGACAAC A GAAAAAGG
6952
CCUUUUUC CUGAUGAGGCCGUUAGGCCGAA IUUGUCGA
16292





4192
AAAAGGAC C UCGGACUG
6953
CAGUCCGA CUGAUGAGGCCGUUAGGCCGAA IUCCUUUU
16293





4193
AAAGGACC U CGGACUGC
6954
GCAGUCCG CUGAUGAGGCCGUUAGGCCGAA IGUCCUUU
16294





4199
CCUCGGAC U GCAGGGAG
6955
CUCCCUGC CUGAUGAGGCCGUUAGGCCGAA IUCCGAGG
16295





4202
CGGACUGC A GGGAGCCA
6956
UGGCUCCC CUGAUGAGGCCGUUAGGCCGAA ICAGUCCG
16296





4209
CAGGGAGC C AGCUCUUC
6957
GAAGAGCU CUGAUGAGGCCGUUAGGCCGAA ICUCCCUG
16297





4210
AGGGAGCC A GCUCUUCU
6958
AGAAGAGC CUGAUGAGGCCGUUAGGCCGAA IGCUCCCU
16298





4213
GAGCCAGC U CUUCUAGG
6959
CCUAGAAG CUGAUGAGGCCGUUAGGCCGAA ICUGGCUC
16299





4215
GCCAGCUC U UCUAGGCU
6960
AGCCUAGA CUGAUGAGGCCGUUAGGCCGAA IAGCUGGC
16300





4218
AGCUCUUC U AGGCUUGU
6961
ACAAGCCU CUGAUGAGGCCGUUAGGCCGAA IAAGAGCU
16301






Core Sequence = CUGAUGAG GCCGUUAGGC CGAA.




Underlined region can be any X sequence or linker, as described herein.




“I” represents Inosine








[0356]

20





TABLE XVII










KDR G-Cleaver Ribozyme and Target Sequences













Seq ID

Seq ID


Pos
Target
No
Ribozyme Sequence
No














12
GCAAGGUGCU G CUGGC
6962
GCCAG UGAUG GCAUGCACUAUGC GCG AGCACCUUGC
16302


22
GCUGGCCGUC G CCCUG
6963
CAGGG UGAUG GCAUGCACUAUGC GCG GACGGCCAGC
16303


35
CUGUGGCUCU G CGUGG
6964
CCACG UGAUG GCAUGCACUAUGC GCG AGAGCCACAG
16304


52
GACCCGGGCC G CCUCU
6965
AGAGG UGAUG GCAUGCACUAUGC GCG GGCCCGGGUC
16305


66
CUGUGGGUUU G CCUAG
6966
CUAGG UGAUG GCAUGCACUAUGC GCG AAACCCACAG
16306


82
UGUUUCUCUU G AUCUG
6967
CAGAU UGAUG GCAUGCACUAUGC GCG AAGAGAAACA
16307


87
CUCUUGAUCU G CCCAG
6968
CUGGG UGAUG GCAUGCACUAUGC GCG AGAUCAAGAG
16308


152
CAAAUUACUU G CAGGG
6969
CCCUG UGAUG GCAUGCACUAUGC GCG AAGUAAUUUG
16309


205
GAGUGGCAGU G AGCAA
6970
UUGCU UGAUG GCAUGCACUAUGC GCG ACUGCCACUC
16310


222
GGGUGGAGGU G ACUGA
6971
UCAGU UGAUG GCAUGCACUAUGC GCG ACCUCCACCC
16311


226
GGAGGUGACU G AGUGC
6972
GCACU UGAUG GCAUGCACUAUGC GCG AGUCACCUCC
16312


230
GUGACUGAGU G CAGCG
6973
CGCUG UGAUG GCAUGCACUAUGC GCG ACUCAGUCAC
16313


235
UGAGUGCAGC G AUGGC
6974
GCCAU UGAUG GCAUGCACUAUGC GCG GCUGCACUCA
16314


273
UUCCAAAAGU G AUCGG
6975
CCGAU UGAUG GCAUGCACUAUGC GCG ACUUUUGGAA
16315


283
GAUCGGAAAU G ACACU
6976
AGUGU UGAUG GCAUGCACUAUGC GCG AUUUCCGAUC
16316


302
GCCUACAAGU G CUUCU
6977
AGAAG UGAUG GCAUGCACUAUGC GCG ACUUGUAGGC
16317


319
CCGGGAAACU G ACUUG
6978
CAAGU UGAUG GCAUGCACUAUGC GCG AGUUUCCCGG
16318


373
UCCAUUUAUU C CUUCU
6979
AGAAG UGAUG GCAUGCACUAUGC GCG AAUAAAUGGA
16319


385
UUCUGUUAGU G ACCAA
6980
UUGGU UGAUG GCAUGCACUAUGC GCG ACUAACAGAA
16320


412
GUACAUUACU G AGAAC
6981
GUUCU UGAUG GCAUGCACUAUGC GCG AGUAAUGUAC
16321


435
AAACUGUGGU G AUUCC
6982
GGAAU UGAUG GCAUGCACUAUGC GCG ACCACAGUUU
16322


481
GUCACUUUGU G CAAGA
6983
UCUUG UGAUG GCAUGCACUAUGC GCG ACAAAGUGAC
16323


511
AUUUGUUCCU G AUGGU
6984
ACCAU UGAUG GCAUGCACUAUGC GCG AGGAACAAAU
16324


567
CCAGCUACAU G AUCAG
6985
CUGAU UGAUG GCAUGCACUAUGC GCG AUGUAGCUGG
16325


577
GAUCAGCUAU G CUGGC
6986
GCCAG UGAUG GCAUGCACUAUGC GCG AUAGCUGAUC
16326


595
GGUCUUCUGU G AAGCA
6987
UGCUU UGAUG GCAUGCACUAUGC GCG ACAGAAGACC
16327


610
AAAAAUUAAU G AUGAA
6988
UUCAU UGAUG GCAUGCACUAUGC GCG AUUAAUUUUU
16328


613
AAUUAAUGAU G AAAGU
6989
ACUUU UGAUG GCAUGCACUAUGC GCG AUCAUUAAUU
16329


667
UAGGAUUUAU G AUGUG
6990
CACAU UGAUG GCAUGCACUAUGC GCG AUAAAUCCUA
16330


678
AUGUGGUUCU G AGUCC
6991
GGACU UGAUG GCAUGCACUAUGC GCG AGAACCACAU
16331


697
UCAUGGAAUU G AACUA
6992
UAGUU UGAUG GCAUGCACUAUGC GCG AAUUCCAUGA
16332


745
AGCAAGAACU G AACUA
6993
UAGUU UGAUG GCAUGCACUAUGC GCG AGUUCUUGCU
16333


763
UGUGGGGAUU G ACUUC
6994
GAAGU UGAUG GCAUGCACUAUGC GCG AAUCCCCACA
16334


789
ACCCUUCUUC G AAGCA
6995
UGCUU UGAUG GCAUGCACUAUGC GCG GAAGAAGGGU
16335


818
CUUGUAAACC G AGACC
6996
GGUCU UGAUG GCAUGCACUAUGC GCG GGUUUACAAG
16336


844
GUCUGGGAGU G AGAUG
6997
CAUCU UGAUG GCAUGCACUAUGC GCG ACUCCCAGAC
16337


849
GGAGUGAGAU G AAGAA
6998
UUCUU UGAUG GCAUGCACUAUGC GCG AUCUCACUCC
16338


861
AGAAAUUUUU G AGCAC
6999
GUGCU UGAUG GCAUGCACUAUGC GCG AAAAAUUUCU
16339


895
AACCCGGAGU G ACCAA
7000
UUGGU UGAUG GCAUGCACUAUGC GCG ACUCCGGGUU
16340


916
GUACACCUGU G CAGCA
7001
UGCUG UGAUG GCAUGCACUAUGC CCC ACACCUCUAC
16341


933
CCAGUGGGCU G AUGAC
7002
GUCAU UGAUC GCAUCCACUAUGC GCG AGCCCACUGG
16342


936
GUGGGCUGAU G ACCAA
7003
UUGGU UGAUG GCAUGCACUAUGC GCG AUCAGCCCAC
16343


970
CAGGGUCCAU G AAAAA
7004
UUUUU UGAUG GCAUGCACUAUGC GCG AUGGACCCUG
16344


985
ACCUUUUGUU G CUUUU
7005
AAAAG UGAUG GCAUGCACUAUGC GCG AACAAAAGGU
16345


1048
CAGAAUCCCU G CGAAG
7006
CUUCG UGAUG GCAUGCACUAUGC GCG AGGGAUUCUG
16346


1050
GAAUCCCUGC G AAGUA
7007
UACUU UGAUG GCAUGCACUAUCC CCC GCAGCGAUUC
16347


1108
AAUACCCCUU G AGUCC
7008
GGACU UGAUG GCAUGCACUAUGC GCG AAGGGGUAUU
16348


1143
GGCAUGUACU G ACGAU
7009
AUCGU UGAUG GCAUGCACUAUGC GCG AGUACAUGCC
16349


1146
AUGUACUGAC G AUUAU
7010
AUAAU UGAUG GCAUGCACUAUGC GCG GUCAGUACAU
16350


1158
UUAUGGAAGU G AGUGA
7011
UCACU UGAUG GCAUGCACUAUGC GCG ACUUCCAUAA
16351


1162
GGAAGUGAGU G AAAGA
7012
UCUUU UGAUG GCAUGCACUAUGC GCG ACUCACUUCC
16352


1267
CCAGAUUGGU G AGAAA
7013
UUUCU UGAUG GCAUGCACUAUGC GCG ACCAAUCUGG
16353


1320
CCACUCAAAC G CUGAC
7014
GUCAG UGAUG GCAUGCACUAUGC GCG GUUUGAGUGG
16354


1323
CUCAAACGCU G ACAUG
7015
CAUGU UGAUG GCAUGCACUAUGC GCG AGCGUUUGAG
16355


1339
UACGGUCUAU G CCAUU
7016
AAUGG UGAUG GCAUGCACUAUGC GCG AUAGACCGUA
16356


1353
UUCCUCCCCC G CAUCA
7017
UGAUG UGAUG GCAUGCACUAUGC GCG GGGGGAGGAA
16357


1391
GAGGAAGAGU G CGCCA
7018
UGGCG UGAUG GCAUGCACUAUGC GCG ACUCUUCCUC
16358


1393
GGAAGAGUGC G CCAAC
7019
GUGUG UGAUG GCAUGCACUAUGC GCG GCACUCUUCC
16359


1399
GUGCGCCAAC G AGCCC
7020
GGGCU UGAUG GCAUGCACUAUGC GCG GUUGGCGCAC
16360


1422
CUGUCUCAGU G ACAAA
7021
UUUGU UGAUG GCAUGCACUAUGC GCG ACUGAGACAG
16361


1441
AUACCCUUGU G AAGAA
7022
UUCUU UGAUG GCAUGCACUAUGC GCG ACAAGGGUAU
16362


1486
AAAUAAAAUU G AAGUU
7023
AACUU UGAUG GCAUGCACUAUGC GCG AAUUUUAUUU
16363


1507
AAAUCAAUUU G CUCUA
7024
UAGAG UGAUG GCAUGCACUAUGC GCG AAAUUGAUUU
16364


1516
UGCUCUAAUU G AAGGA
7025
UCCUU UGAUG GCAUGCACUAUGC GCG AAUUAGAGCA
16365


1585
GUACAAAUGU G AAGCG
7026
CGCUU UGAUG GCAUGCACUAUGC GCG ACAUUUGUAC
16366


1620
GAGAGAGGGU G AUCUC
7027
GAGAU UGAUG GCAUGCACUAUGC GCG ACCCUCUCUC
16367


1635
CCUUCCACGU G ACCAG
7028
CUGGU UGAUG GCAUGCACUAUGC GCG ACGUGGAAGG
16368


1648
CAGGGGUCCU G AAAUU
7029
AAUUU UGAUG GCAUGCACUAUGC GCG AGGACCCCUG
16369


1659
AAAUUACUUU G CAACC
7030
GGUUG UGAUG GCAUGCACUAUGC GCG AAAGUAAUUU
16370


1666
UUUGCAACCU G ACAUG
7031
CAUGU UGAUG GCAUGCACUAUGC GCG AGGUUGCAAA
16371


1671
AACCUGACAU G CAGCC
7032
GGCUG UGAUG GCAUGCACUAUGC GCG AUGUCAGGUU
16372


1681
GCAGCCCACU G AGCAG
7033
CUGCU UGAUG GCAUGCACUAUGC GCG AGUGGGCUGC
16373


1706
UCUUUGUGGU G CACUG
7034
CAGUG UGAUG GCAUGCACUAUGC GCG ACCACAAAGA
16374


1711
GUGGUGCACU G CAGAC
7035
GUCUG UGAUG GCAUGCACUAUGC GCG AGUGCACCAC
16375


1729
AUCUACGUUU G AGAAC
7036
GUUCU UGAUG GCAUGCACUAUGC GCG AAACGUAGAU
16376


1767
CACAGCCUCU G CCAAU
7037
AUUGG UGAUG GCAUGCACUAUGC GCG AGAGGCUGUG
16377


1788
UGGGAGAGUU G CCCAC
7038
GUGGG UGAUG GCAUGCACUAUGC GCG AACUCUCCCA
16378


1802
ACACCUGUUU G CAAGA
7039
UCUUG UGAUG GCAUGCACUAUGC GCG AAACAGGUGU
16379


1830
UUUGGAAAUU G AAUGC
7040
GCAUU UGAUG GCAUGCACUAUGC GCG AAUUUCCAAA
16380


1834
GAAAUUGAAU G CCACC
7041
GGUGG UGAUG GCAUGCACUAUGC GCG AUUCAAUUUC
16381


1861
UAGCACAAAU G ACAUU
7042
AAUGU UGAUG GCAUGCACUAUGC GCG AUUUGUGCUA
16382


1869
AUGACAUUUU G AUCAU
7043
AUGAU UGAUG GCAUGCACUAUGC GCG AAAAUGUCAU
16383


1888
GCUUAAGAAU G CAUCC
7044
GGAUG UGAUG GCAUGCACUAUGC GCG AUUCUUAAGC
16384


1896
AUGCAUCCUU G CAGGA
7045
UCCUG UGAUG GCAUGCACUAUGC GCG AAGGAUGCAU
16385


1919
GACUAUGUCU G CCUUG
7046
CAAGG UGAUG GCAUGCACUAUGC GCG AGACAUAGUC
16386


1924
UGUCUGCCUU G CUCAA
7047
UUGAG UGAUG GCAUGCACUAUGC GCG AAGGCAGACA
16387


1955
AAAAGACAUU G CGUGG
7048
CCACG UGAUG GCAUGCACUAUGC GCG AAUGUCUUUU
16388


1998
UGGCACCCAC G AUCAC
7049
GUGAU UGAUG GCAUGCACUAUGC GCG GUGGGUGCCA
16389


2025
AGAAUCAGAC G ACAAG
7050
CUUGU UGAUG GCAUGCACUAUGC GCG GUCUGAUUCU
16390


2047
GGAAAGCAUC G AAGUC
7051
GACUU UGAUG GCAUGCACUAUGC GCG GAUGCUUUCC
16391


2057
GAAGUCUCAU G CACGG
7052
CCGUG UGAUG GCAUGCACUAUGC GCG AUGAGACUUC
16392


2107
UAAAGAUAAU G AGACC
7053
GGUCU UGAUG GCAUGCACUAUGC GCG AUUAUCUUUA
16393


2139
GCAUUGUAUU G AAGGA
7054
UCCUU UGAUG GCAUGCACUAUGC GCG AAUACAAUGC
16394


2168
CUCACUAUCC G CAGAG
7055
CUCUG UGAUG GCAUGCACUAUGC GCG GGAUAGUGAG
16395


2175
UCCGCAGAGU G AGGAA
7056
UUCCU UGAUG GCAUGCACUAUGC GCG ACUCUGCGGA
16396


2188
GAAGGAGGAC G AAGGC
7057
GCCUU UGAUG GCAUGCACUAUGC GCG GUCCUCCUUC
16397


2204
CUCUACACCU G CCAGG
7058
CCUGG UGAUG GCAUGCACUAUGC GCG AGGUGUAGAG
16398


2213
UGCCAGGCAU G CAGUG
7059
CACUG UGAUG GCAUGCACUAUGC GCG AUGCCUGGCA
16399


2230
UCUUGGCUGU G CAAAA
7060
UUUUG UGAUG GCAUGCACUAUGC GCG ACAGCCAAGA
16400


2263
AAUAGAAGGU G CCCAG
7061
CUGGG UGAUG GCAUGCACUAUGC GCG ACCUUCUAUU
16401


2277
AGGAAAAGAC G AACUU
7062
AAGUU UGAUG GCAUGCACUAUGC GCG GUCUUUUCCU
16402


2307
UAGUAGGCAC G ACGGU
7063
ACCGU UGAUG GCAUGCACUAUGC GCG GUGCCUACUA
16403


2313
GCACGACGGU G AUUGC
7064
GCAAU UGAUG GCAUGCACUAUGC GCG ACCGUCGUGC
16404


2317
GACGGUGAUU G CCAUG
7065
CAUGG UGAUG GCAUGCACUAUGC GCG AAUCACCGUC
16405


2385
GAGGGGAACU G AAGAC
7066
GUCUU UGAUG GCAUGCACUAUGC GCG AGUUCCCCUC
16406


2422
GGAUCCAGAU G AACUC
7067
GAGUU UGAUG GCAUGCACUAUGC GCG AUCUGGAUCC
16407


2437
CCCAUUGGAU G AACAU
7068
AUGUU UGAUG GCAUGCACUAUGC GCG AUCCAAUGGG
16408


2446
UGAACAUUGU G AACGA
7069
UCGUU UGAUG GCAUGCACUAUGC GCG ACAAUGUUCA
16409


2450
CAUUGUGAAC G ACUGC
7070
GCAGU UGAUG GCAUGCACUAUGC GCG GUUCACAAUG
16410


2454
GUGAACGACU G CCUUA
7071
UAAGG UGAUG GCAUGCACUAUGC GCG AGUCGUUCAC
16411


2461
ACUGCCUUAU G AUGCC
7072
GGCAU UGAUG GCAUGCACUAUGC GCG AUAAGGCAGU
16412


2464
GCCUUAUGAU G CCAGC
7073
GCUGG UGAUG GCAUGCACUAUGC GCG AUCAUAAGGC
16413


2496
GAGACCGGCU G AACCU
7074
AGGUU UGAUG GCAUGCACUAUGC GCG AGCCGGUCUC
16414


2524
UGGCCGUGGU G CCUUU
7075
AAAGG UGAUG GCAUGCACUAUGC GCG ACCACGGCCA
16415


2542
CCAAGAGAUU G AAGCA
7076
UGCUU UGAUG GCAUGCACUAUGC GCG AAUCUCUUGG
16416


2551
UGAAGCAGAU G CCUUU
7077
AAAGG UGAUG GCAUGCACUAUGC GCG AUCUGCUUCA
16417


2563
CUUUGGAAUU G ACAAG
7078
CUUGU UGAUG GCAUGCACUAUGC GCG AAUUCCAAAG
16418


2579
ACAGCAACUU G CAGGA
7079
UCCUG UGAUG GCAUGCACUAUGC GCG AAGUUGCUGU
16419


2604
UCAAAAUGUU G AAAGA
7080
UCUUU UGAUG GCAUGCACUAUGC GCG AACAUUUUGA
16420


2626
AACACACAGU G AGCAU
7081
AUGCU UGAUG GCAUGCACUAUGC GCG ACUGUGUGUU
16421


2633
AGUGAGCAUC G ACCUC
7082
GAGCU UGAUG GCAUGCACUAUGC GCG GAUGCUCACU
16422


2647
UCUCAUGUCU G AACUC
7083
GAGUU UGAUG GCAUGCACUAUGC GCG AGACAUGAGA
16423


2704
CCUUCUAGGU G CCUGU
7084
ACAGG UGAUG GCAUGCACUAUGC GCG ACCUAGAAGG
16424


2736
CACUCAUGGU G AUUGU
7085
ACAAU UGAUG GCAUGCACUAUGC GCG ACCAUGAGUG
16425


2750
GUGGAAUUCU G CAAAU
7086
AUUUG UGAUG GCAUGCACUAUGC GCG AGAAUUCCAC
16426


2778
CCACUUACCU G AGGAG
7087
CUCCU UGAUG GCAUGCACUAUGC GCG AGGUAAGUGG
16427


2794
CAAGAGAAAU G AAUUU
7088
AAAUU UGAUG GCAUGCACUAUGC GCG AUUUCUCUUG
16428


2825
AAAGGGGCAC G AUUCC
7089
GGAAU UGAUG GCAUGCACUAUGC GCG GUGCCCCUUU
16429


2871
CUGUGGAUCU G AAACG
7090
CGUUU UGAUG GCAUGCACUAUGC GCG AGAUCCACAG
16430


2879
CUGAAACGGC G CUUGG
7091
CCAAG UGAUG GCAUGCACUAUGC GCG GCCGUUUCAG
16431


2947
GUCCCUCAGU G AUGUA
7092
UACAU UGAUG GCAUGCACUAUGC GCG ACUGAGGGAC
16432


2971
GGAAGCUCCU G AAGAU
7093
AUCUU UGAUG GCAUGCACUAUGC GCG AGGAGCUUCC
16433


2994
AGGACUUCCU G ACCUU
7094
AAGGU UGAUG GCAUGCACUAUGC GCG AGGAAGUCCU
16434


3057
UCUUGGCAUC G CGAAA
7095
UUUCG UGAUG GCAUGCACUAUGC GCG GAUGCCAAGA
16435


3059
UUGGCAUCGC G AAAGU
7096
ACUUU UGAUG GCAUGCACUAUGC GCG GCGAUGCCAA
16436


3089
CUGGCGGCAC G AAAUA
7097
UAUUU UGAUG GCAUGCACUAUGC GCG GUGCCGCCAG
16437


3130
UAAAAUCUGU G ACUUU
7098
AAAGU UGAUG GCAUGCACUAUGC GCG ACAGAUUUUA
16438


3187
AAAAGGAGAU G CUCGC
7099
GCGAG UGAUG GCAUGCACUAUGC GCG AUCUCCUUUU
16439


3191
GGAGAUGCUC G CCUCC
7100
GGAGG UGAUG GCAUGCACUAUGC GCG GAGCAUCUCC
16440


3201
GCCUCCCUUU G AAAUG
7101
CAUUU UGAUG GCAUGCACUAUGC GCG AAAGGGAGGC
16441


3229
AACAAUUUUU G ACAGA
7102
UCUGU UGAUG GCAUGCACUAUGC GCG AAAAAUUGUU
16442


3253
AAUCCAGAGU G ACUUC
7103
GACGU UGAUG GCAUGCACUAUGC GCG ACUCUGGAUU
16443


3276
UUGGUGUUUU G CUGUG
7104
CACAG UGAUG GCAUGCACUAUGC GCG AAAACACCAA
16444


3301
UUCCUUAGGU G CUUCU
7105
AGAAG UGAUG GCAUGCACUAUGC GCG ACCUAAGGAA
16445


3328
GGUAAAGAUU G AUGAA
7106
UUCAU UGAUG GCAUGCACUAUGC GCG AAUCUUUACC
16446


3331
AAAGAUUGAU G AAGAA
7107
UUCUU UGAUG GCAUGCACUAUGC GCG AUCAAUCUUU
16447


3347
UUUUGUAGGC G AUUGA
7108
UCAAU UGAUG GCAUGCACUAUGC GCG GCCUACAAAA
16448


3351
GUAGGCGAUU G AAAGA
7109
UCUUU UGAUG GCAUGCACUAUGC GCG AAUCGCCUAC
16449


3369
GAACUAGAAU G AGGGC
7110
GCCCU UGAUG GCAUGCACUAUGC GCG AUUCUAGUUC
16450


3379
GAGGGCCCCU G AUUAU
7111
AUAAU UGAUG GCAUGCACUAUGC GCG AGGGGCCCUC
16451


3411
ACCAGACCAU G CUGGA
7112
UCCAG UGAUG GCAUGCACUAUGC GCG AUGGUCUGGU
16452


3419
AUGCUGGACU G CUGGC
5872
GCCAG UGAUG GCAUGCACUAUGC GCG AGUCCAGCAU
15212


3486
GAAAUCUCUU G CAAGC
7113
GCUUG UGAUG GCAUGCACUAUGC GCG AAGAGAUUUC
16453


3496
GCAAGCUAAU G CUCAG
7114
CUGAG UGAUG GCAUGCACUAUGC GCG AUUAGCUUGC
16454


3531
UUGUUCUUCC G AUAUC
7115
GAUAU UGAUG GCAUGCACUAUGC GCG GGAAGAACAA
16455


3546
CAGAGACUUU G AGCAU
7116
AUGCU UGAUG GCAUGCACUAUGC GCG AAAGUCUCUG
16456


3576
GACUCUCUCU G CCUAC
7117
GUAGG UGAUG GCAUGCACUAUGC GCG AGAGAGAGUC
16457


3619
GGAAGUAUGU G ACCCC
7118
GGGGU UGAUG GCAUGCACUAUGC GCG ACAUACUUCC
16458


3637
AUUCCAUUAU G ACAAC
7119
GUUGU UGAUG GCAUGCACUAUGC GCG AUAAUGGAAU
16459


3666
GUCAGUAUCU G CAGAA
7120
UCCUG UGAUG GCAUGCACUAUGC GCG AGAUACUGAC
16460


3680
AACAGUAAGC G AAAGA
7121
UCUUU UGAUG GCAUGCACUAUGC GCG GCUUACUGUU
16461


3696
GCCGGCCUGU G AGUGU
7122
ACACU UGAUG GCAUGCACUAUGC GCG ACAGGCCGGC
16462


3712
AAAAACAUUU G AAGAU
7123
AUCUU UGAUG GCAUGCACUAUGC GCG AAAUGUUUUU
16463


3757
AAUCCCAGAU G ACAAC
7124
GUUGU UGAUG GCAUGCACUAUGC GCG AUCUGGGAUU
16464


3787
UAUGGUUCUU G CCUCA
7125
UGAGG UGAUG GCAUGCACUAUGC GCG AAGAACCAUA
16465


3801
CAGAAGAGCU G AAAAC
7126
GUUUU UGAUG GCAUGCACUAUGC GCG AGCUCUUCUG
16466


3852
GUGGAAUGGU G CCCAG
7127
CUGGG UGAUG GCAUGCACUAUGC GCG ACCAUUCCAC
16467


3883
UGUGGCAUCU G AAGGC
7128
GCCUU UGAUG GCAUGCACUAUGC GCG AGAUGCCACA
16468


3928
AUAUCACUCC G AUGAC
7129
GUCAU UGAUG GCAUGCACUAUGC GCG GGAGUGAUAU
16469


3931
UCACUCCGAU G ACACA
7130
UGUGU UGAUG GCAUGCACUAUGC GCG AUCGGAGUGA
16470


3958
GUACUCCAGU G AGGAA
7131
UUCCU UGAUG GCAUGCACUAUGC GCG ACUGGAGUAC
16471


3981
UUUUAAAGCU G AGAGA
7132
UCUAU UGAUG GCAUGCACUAUGC GCG AGCUUUAAAA
16472


3996
AGAUUGGAGU G CAAAC
7133
GUUUG UGAUG GCAUGCACUAUGC GCG ACUCCAAUCU
16473


4030
UCUCCAGCCU G ACACG
7134
CGUGU UGAUG GCAUGCACUAUGC GCG AGGCUGGAGA
16474


4047
GGACCACACU G AGCUC
7135
GAGCU UGAUG GCAUGCACUAUGC GCG AGUGUGGUCC
16475


4103
GACAUCACAU G AGAGG
7136
CCUCU UGAUG GCAUGCACUAUGC GCG AUGUGAUGUC
16476


4112
UGAGAGGUCU G CUCAG
7137
CUGAG UGAUG GCAUGCACUAUGC GCG AGACCUCUCA
16477


4123
CUCAGAUUUU G AAGUG
7138
CACUU UGAUG GCAUGCACUAUGC GCG AAAAUCUGAG
16478


4157
GGAAGUAGCC G CAUUU
7139
AAAUG UGAUG GCAUGCACUAUGC GCG GGCUACUUCC
16479


4163
AGCCGCAUUU G AUUUU
7140
AAAAU UGAUG GCAUGCACUAUGC GCG AAAUGCGGCU
16480


4175
UUUUCAUUUC G ACAAC
7141
GUUGU UGAUG GCAUGCACUAUGC GCG GAAAUGAAAA
16481


4200
ACCUCGGACU G CAGGG
7142
CCCUG UGAUG GCAUGCACUAUGC GCG AGUCCGAGGU
16482










[0357]

21





TABLE XVIII










Human FLT DNAzyme and Substrate Sequence













Seq ID

Seq ID


Pos
Substrate
No
DNAzyme
No














17
UCCUCUCG G CUCCUCCC
7143
GGGAGGAG GGCTAGCTACAACGA CGAGAGGA
16483


28
CCUCCCCG G CAGCGGCG
7144
CGCCGCTG GGCTAGCTACAACGA CGGGGAGG
16484


31
CCCCGGCA G CGGCGGCG
7145
CGCCGCCG GGCTAGCTACAACGA TGCCGGGG
16485


34
CGGCAGCG G CGGCGGCU
7146
AGCCGCCG GGCTAGCTACAACGA CGCTGCCG
16486


37
CAGCGGCG G CGGCUCGG
7147
CCGAGCCG GGCTAGCTACAACGA CGCCGCTG
16487


40
CGGCGGCG G CUCGGAGC
7148
GCTCCGAG GGCTAGCTACAACGA CGCCGCCG
16488


47
GGCUCGGA G CGGGCUCC
7149
GGAGCCCG GGCTAGCTACAACGA TCCGAGCC
16489


51
CGGAGCGG G CUCCGGGG
7150
CCCCGGAG GGCTAGCTACAACGA CCGCTCCG
16490


59
GCUCCGGG G CUCGGGUG
7151
CACCCGAG GGCTAGCTACAACGA CCCGGAGC
16491


65
GGGCUCGG G UGCAGCGG
7152
CCGCTGCA GGCTAGCTACAACGA CCGAGCCC
16492


67
GCUCGGGU G CAGCGGCC
7153
GGCCGCTG GGCTAGCTACAACGA ACCCGAGC
16493


70
CGGGUGCA G CGGCCAGC
7154
GCTGGCCG GGCTAGCTACAACGA TGCACCCG
16494


73
GUGCAGCG G CCAGCGGG
7155
CCCGCTGG GGCTAGCTACAACGA CGCTGCAC
16495


77
AGCGCCCA G CGGGCCUG
7156
CAGGCCCG GGCTAGCTACAACGA TGGCCGCT
16496


81
GCCAGCGG G CCUGGCGG
7157
CCGCCAGG GGCTAGCTACAACGA CCGCTGGC
16497


86
CGGGCCUG G CGGCGAGG
7158
CCTCGCCG GGCTAGCTACAACGA CAGGCCCG
16498


89
GCCUGGCG G CGAGGAUU
7159
AATCCTCG GGCTAGCTACAACGA CGCCAGGC
16499


95
CGGCGAGG A UUACCCGG
7160
CCGGGTAA GGCTAGCTACAACGA CCTCGCCG
16500


98
CGAGGAUU A CCCGGGGA
10
TCCCCGGG GGCTAGCTACAACGA AATCCTCG
16501


108
CCGGGGAA G UGGUUGUC
7161
GACAACCA GGCTAGCTACAACGA TTCCCCGG
16502


111
GGGAAGUG G UUGUCUCC
7162
GGAGACAA GGCTAGCTACAACGA CACTTCCC
16503


114
AAGUGGUU G UCUCCUGG
7163
CCAGGAGA GGCTAGCTACAACGA AACCACTT
16504


122
GUCUCCUG G CUGGAGCC
7164
GGCTCCAG GGCTAGCTACAACGA CAGGAGAC
16505


128
UGGCUGGA G CCGCGAGA
7165
TCTCGCGG GGCTAGCTACAACGA TCCAGCCA
16506


131
CUGGAGCC G CGAGACGG
7166
CCGTCTCG GGCTAGCTACAACGA GGCTCCAG
16507


136
GCCGCGAG A CGGGCGCU
7167
AGCGCCCG GGCTAGCTACAACGA CTCGCGGC
16508


140
CGAGACGG G CGCUCAGG
7168
CCTGAGCG GGCTAGCTACAACGA CCGTCTCG
16509


142
AGACGGGC G CUCAGGGC
7169
GCCCTGAG GGCTAGCTACAACGA GCCCGTCT
16510


149
CGCUCAGG G CGCGGGGC
7170
GCCCCGCG GGCTAGCTACAACGA CCTGAGCG
16511


151
CUCAGGGC G CGGGGCCG
7171
CGGCCCCG GGCTAGCTACAACGA GCCCTGAG
16512


156
GGCGCGGG G CCGGCGGC
7172
GCCGCCGG GGCTAGCTACAACGA CCCGCGCC
16513


160
CGGGGCCG G CGGCGGCG
7173
CGCCGCCG GGCTAGCTACAACGA CGGCCCCG
16514


163
GGCCGGCG G CGGCGAAC
7174
GTTCGCCG GGCTAGCTACAACGA CGCCGGCC
16515


166
CGGCGGCG G CGAACGAG
7175
CTCGTTCG GGCTAGCTACAACGA CGCCGCCG
16516


170
GGCGGCGA A CGAGAGGA
7176
TCCTCTCG GGCTAGCTACAACGA TCGCCGCC
16517


178
ACGAGAGG A CGGACUCU
7177
AGAGTCCG GGCTAGCTACAACGA CCTCTCGT
16518


182
GAGGACGG A CUCUGGCG
7178
CGCCAGAG GGCTAGCTACAACGA CCGTCCTC
16519


188
GGACUCUG G CGGCCGGG
7179
CCCGGCCG GGCTAGCTACAACGA CAGAGTCC
16520


191
CUCUGGCG G CCGGGUCG
7180
CGACCCGG GGCTAGCTACAACGA CGCCAGAG
16521


196
GCGGCCGG G UCGUUGGC
7181
GCCAACGA GGCTAGCTACAACGA CCGGCCGC
16522


199
GCCGGGUC G UUGGCCGG
7182
CCGGCCAA GGCTAGCTACAACGA GACCCGGC
16523


203
GGUCGUUG G CCGGGGGA
7183
TCCCCCGG GGCTAGCTACAACGA CAACGACC
16524


212
CCGGGGGA G CGCGGGCA
7184
TGCCCGCG GGCTAGCTACAACGA TCCCCCGG
16525


214
GGGGGAGC G CGGGCACC
7185
GGTGCCCG GGCTAGCTACAACGA GCTCCCCC
16526


218
GAGCGCGG G CACCGGGC
7186
GCCCGGTG GGCTAGCTACAACGA CCGCGCTC
16527


220
GCGCGGGC A CCGGGCGA
4191
UCGCCCGG GGCTAGCTACAACGA GCCCGCGC
16528


225
GGCACCGG G CGAGCAGG
7187
CCTGCTCG GGCTAGCTACAACGA CCGGTGCC
16529


229
CCGGGCGA G CAGGCCGC
7188
GCGGCCTG GGCTAGCTACAACGA TCGCCCGG
16530


233
GCGAGCAG G CCGCGUCG
7189
CGACGCGG GGCTAGCTACAACGA CTGCTCGC
16531


236
AGCAGGCC G CGUCGCGC
7190
GCGCGACG GGCTAGCTACAACGA GGCCTGCT
16532


238
CAGGCCGC G UCGCGCUC
7191
GAGCGCGA GGCTAGCTACAACGA GCGGCCTG
16533


241
GCCGCGUC G CGCUCACC
7192
GGTGAGCG GGCTAGCTACAACGA GACGCGGC
16534


243
CGCGUCGC G CUCACCAU
7193
ATGGTGAG GGCTAGCTACAACGA GCGACGCG
16535


247
UCGCGCUC A CCAUGGUC
4196
GACCATGG GGCTAGCTACAACGA GAGCGCGA
16536


250
CGCUCACC A UGGUCAGC
4198
GCTGACCA GGCTAGCTACAACGA GGTGAGCG
16537


253
UCACCAUG C UCAGCUAC
7194
GTAGCTGA GGCTAGCTACAACGA CATGGTGA
16538


257
CAUGGUCA G CUACUGGG
7195
CCCAGTAG GGCTAGCTACAACGA TGACCATG
16539


260
GGUCAGCU A CUGGGACA
21
UGTCCCAG GGCTAGCTACAACGA AGCTGACC
16540


266
CUACUGGG A CACCGGGG
7196
CCCCGGTG GGCTAGCTACAACGA CCCAGTAG
16541


268
ACUGGGAC A CCGGGGUC
4202
GACCCCGG GGCTAGCTACAACGA GTCCCAGT
16542


274
ACACCGGG C UCCUGCUG
7197
CACCAGGA GGCTAGCTACAACGA CCCGGTGT
16543


279
GGGGUCCU G CUGUGCGC
7198
GCGCACAG GGCTAGCTACAACGA AGGACCCC
16544


282
GUCCUGCU G UGCGCGCU
7199
ACCGCGCA GGCTAGCTACAACGA AGCAGGAC
16545


284
CCUGCUGU G CGCGCUGC
7200
GCAGCGCG GGCTAGCTACAACGA ACAGCAGG
16546


286
UGCUGUGC G CGCUGCUC
7201
GAGCAGCG GGCTAGCTACAACGA GCACAGCA
16547


288
CUGUGCGC C CUCCUCAG
7202
CTGAGCAG GCCTAGCTACAACGA GCGCACAG
16548


291
UGCGCGCU C CUCAGCUG
7203
CAGCTGAG GGCTAGCTACAACGA AGCGCGCA
16549


296
GCUCCUCA C CUGUCUGC
7204
GCAGACAG CGCTAGCTACAACGA TGAGCAGC
16550


299
CCUCAGCU G UCUCCGUC
7205
GAAGCAGA GGCTAGCTACAACGA AGCTGAGC
16551


303
AGCUCUCU G CUUCUCAC
7206
GTGAGAAG CGCTAGCTACAACGA AGACAGCT
16552


310
UGCUUCUC A CACCAUCU
4214
AGATCCTG GGCTAGCTACAACGA GAGAAGCA
16553


315
CUCACACG A UCUAGUUC
7207
GAACTAGA CGCTACCTACAACGA CCTGTGAC
16554


320
ACCAUCUA G UUCAGCUU
7208
AACCTGAA GGCTAGCTACAACGA TACATCCT
16555


326
UAGUUCAG C UUCAAAAU
7209
ATTTTGAA GCCTAGCTACAACGA CTGAACTA
16556


333
GGUUCAAA A UUAAAAGA
7210
TCTTTTAA GGCTAGCTACAACGA TTTGAACC
16557


341
AUUAAAAG A UCCUGAAC
7211
GTTCAGGA GGCTAGCTACAACGA CTTTTAAT
16558


348
GAUCCUCA A CUGACUUU
7212
AAACTCAG GGCTAGCTACAACGA TCAGGATC
16559


353
UGAACUGA G UUUAAAAG
7213
CTTTTAAA GGCTAGCTACAACGA TCAGTTCA
16560


362
UUUAAAAG C CACCCAGC
7214
GCTGGGTG GGCTAGCTACAACGA CTTTTAAA
16561


364
UAAAAGGC A CCCAGCAC
4222
CTCCTCCG GGCTAGCTACAACGA GCCTTTTA
16562


369
CCCACCCA C CACAUCAU
7215
ATCATGTC GGCTAGCTACAACGA TCCGTGCC
16563


371
CACCCAGC A CAUCAUGC
4226
GCATGATG GGCTAGCTACAACGA CCTCGGTG
16564


373
CCCAGCAC A UCAUGCAA
4227
TTGCATCA GGCTAGCTACAACGA GTCCTGCC
16565


376
ACCACAUC A UCCAAGCA
4228
TCCTTCCA GGCTAGCTACAACGA CATCTGCT
16566


378
CACAUCAU C CAAGCAGG
7216
CCTGCTTG GGCTACCTACAACGA ATGATGTG
16567


382
UCAUCCAA C CAGGCCAG
7217
CTGGCCTC GGCTAGCTACAACGA TTCCATGA
16568


386
GCAAGCAG C CCAGACAC
7218
GTCTCTGC GGCTAGCTACAACGA CTGCTTCC
16569


391
CACCCCAG A CACUGCAU
7219
ATCCAGTC GGCTACCTACAACGA CTCCCCTC
16570


393
GGCCACAC A CUGCAUCU
4233
ACATCCAC GGCTAGCTACAACGA CTCTGGCC
16571


396
CAGACACU C CAUCUCCA
7220
TGCACATC GGCTAGCTACAACGA ACTGTCTG
16572


398
CACACUGC A UCUCCAAU
4235
ATTGCAGA GGCTAGCTACAACGA GCACTCTC
16573


405
CAUCUCCA A UCCAGGGC
7221
CCCCTCCA GGCTAGCTACAACGA TGCACATG
16574


407
UCUCCAAU C CACGCCGC
7222
CCCCCCTG GGCTAGCTACAACGA ATTGCACA
16575


418
GGGGGGAA C CAGCCCAU
7223
ATCGCCTC GGCTAGCTACAACGA TTCCCCCC
16576


421
GGGAAGCA G CCCAUAAA
7224
TTTATGGG GGCTAGCTACAACGA TGCTTCCC
16577


425
AGCAGCCC A UAAAUGGU
4243
ACCATTTA GGCTAGCTACAACGA GGGCTGCT
16578


429
GCCCAUAA A UGGUCUUU
7225
AAAGACCA GGCTAGCTACAACGA TTATGGGC
16579


432
CAUAAAUG G UCUUUGCC
7226
GGCAAAGA GGCTAGCTACAACGA CATTTATG
16580


438
UGGUCUUU G CCUGAAAU
7227
ATTTCAGG GGCTAGCTACAACGA AAAGACCA
16581


445
UGCCUGAA A UGGUGAGU
7228
ACTCACCA GGCTAGCTACAACGA TTCAGGCA
16582


448
CUGAAAUG G UGAGUAAG
7229
CTTACTCA GGCTAGCTACAACGA CATTTCAG
16583


452
AAUGGUGA G UAAGGAAA
7230
TTTCCTTA GGCTAGCTACAACGA TCACCATT
16584


461
UAAGGAAA G CGAAAGGC
7231
GCCTTTCG GGCTAGCTACAACGA TTTCCTTA
16585


468
AGCGAAAG G CUGAGCAU
7232
ATGCTCAG GGCTAGCTACAACGA CTTTCGCT
16586


473
AAGGCUGA G CAUAACUA
7233
TAGTTATG GGCTAGCTACAACGA TCAGCCTT
16587


475
GGCUGAGC A UAACUAAA
4248
TTTAGTTA GGCTAGCTACAACGA GCTCAGCC
16588


478
UGAGCAUA A CUAAAUCU
7234
AGATTTAG GGCTAGCTACAACGA TATGCTCA
16589


483
AUAACUAA A UCUGCCUG
7235
CAGGCAGA GGCTAGCTACAACGA TTAGTTAT
16590


487
CUAAAUCU G CCUGUGGA
7236
TCCACAGG QGCTAGCTACAACGA AGATTTAG
16591


491
AUCUGCCU G UGGAAGAA
7237
TTCTTCCA GGCTAGCTACAACGA AGGCAGAT
16592


500
UGGAAGAA A UGGCAAAC
7238
GTTTGCCA GGCTAGCTACAACGA TTCTTCCA
16593


503
AAGAAAUG G CAAACAAU
7239
ATTGTTTG GGCTAGCTACAACGA CATTTCTT
16594


507
AAUGGCAA A CAAUUCUG
7240
CAGAATTG GGCTAGCTACAACGA TTGCCATT
16595


510
GGCAAACA A UUCUGCAG
7241
CTGCAGAA GGCTAGCTACAACGA TGTTTGCC
16596


515
ACAAUUCU G CAGUACUU
7242
AAGTACTG GGCTAGCTACAACGA ACAATTGT
16597


518
AUUCUGCA G UACUUUAA
7243
TTAAAGTA GGCTAGCTACAACGA TGCAGAAT
16598


520
UCUGCAGU A CUUUAACC
53
GGTTAAAG GGCTAGCTACAACGA ACTGCAGA
16599


526
GUACUUUA A CCUUGAAC
7244
GTTCAAGG GGCTAGCTACAACGA TAAAGTAC
16600


533
AACCUUGA A CACAGCUC
7245
GAGCTGTG GGCTAGCTACAACGA TCAAGGTT
16601


535
CCUUGAAC A CAGCUCAA
4260
TTGAGCTG GGCTAGCTACAACGA GTTCAAGG
16602


538
UGAACACA G CUCAAGCA
7246
TGCTTGAG GGCTAGCTACAACGA TGTGTTCA
16603


544
CAGCUCAA G CAAACCAC
7247
GTGGTTTG GGCTAGCTACAACGA TTGAGCTG
16604


548
UCAAGCAA A CGACACUG
7248
CAGTGTGG GGCTAGCTACAACGA TTGCTTGA
16605


551
AGCAAACC A CACUGGCU
4266
AGCCAGTG GGCTAGCTACAACGA GGTTTGCT
16606


553
CAAACCAC A CUGGCUUC
4267
GAAGCCAG GGCTAGCTACAACGA GTGGTTTG
16607


557
CGACACUG G CUUCUACA
7249
TGTAGAAG GGCTAGCTACAACGA CAGTGTGG
16608


563
UGGCUUCU A CAGCUGCA
61
UGCAGCTG GGCTAGCTACAACGA AGAAGCCA
16609


566
CUlICUACA G CUGCAAAU
7250
ATTTGCAG GGCTAGCTACAACGA TGTAGAAG
16610


569
CUACAGCU G CAAAUAUC
7251
GATATTTG GGCTAGCTACAACGA AGCTGTAG
16611


573
AGCUGCAA A UAUCUAGC
7252
GCTAGATA GGCTAGCTACAACGA TTGCAGCT
16612


575
CUGCAAAU A UCUAGCUG
62
CAGCTAGA GGCTAGCTACAACGA ATTTGCAG
16613


580
AAUAUCUA G CUGUACCU
7253
AGGTACAG GGCTAGCTACAACGA TAGATATT
16614


583
AUCUAGCU G UACCUACU
7254
AGTAGGTA GGCTAGCTACAACGA AGCTAGAT
16615


585
CUAGCUGU A CCUACUUC
65
GAAGTAGG GGCTAGCTACAACGA ACAGCTAG
16616


589
CUGUACCU A CUUCAAAG
66
CTTTGAAG GGCTAGCTACAACGA AGGTACAG
16617


607
AGAAGGAA A CAGAAUCU
7255
AGATTCTG GGCTAGCTACAACGA TTCCTTCT
16618


612
GAAACAGA A UCUCCAAU
7256
ATTGCAGA GGCTAGCTACAACGA TCTGTTTC
16619


616
CAGAAUCU G CAAUCUAU
7257
ATAGATTG GGCTAGCTACAACGA AGATTCTG
16620


619
AAUCUGCA A UCUAUAUA
7258
TATATAGA GGCTAGCTACAACGA TGCAGATT
16621


623
UGCAAUCU A UAUAUUUA
71
UAAATATA GGCTAGCTACAACGA AGATTGCA
16622


625
CAAUCUAU A UAUUUAUU
72
AATAAATA GGCTAGCTACAACGA ATAGATTG
16623


627
AUCUAUAU A UUUAUUAG
73
CTAATAAA GGCTAGCTACAACGA ATATAGAT
16624


631
AUAUAUUU A UUAGUGAU
76
ATCACTAA GGCTAGCTACAACGA AAATATAT
16625


635
AUUUAUUA G UGAUACAG
7259
CTGTATCA GGCTAGCTACAACGA TAATAAAT
16626


638
UAUUAGUG A UACAGGUA
7260
TACCTGTA GGCTAGCTACAACGA CACTAATA
16627


640
UUAGUGAU A CAGGUAGA
79
TCTACCTG GGCTAGCTACAACGA ATCACTAA
16628


644
UGAUACAG G UAGACCUU
7261
AAGGTCTA GGCTAGCTACAACGA CTGTATCA
16629


648
ACAGGUAG A CCUUUCGU
7262
ACGAAAGG GGCTAGCTACAACGA CTACCTGT
16630


655
GACCUUUC G UAGAGAUG
7263
CATCTCTA GGCTAGCTACAACGA GAAAGGTC
16631


661
UCGUAGAG A UGUACAGU
7264
ACTGTACA GGCTAGCTACAACGA CTCTACGA
16632


663
GUAGAGAU G UACAGUGA
7265
TCACTGTA GGCTAGCTACAACGA ATCTCTAC
16633


665
AGAGAUGU A CAGUGAAA
85
TTTCACTG GGCTAGCTACAACGA ACATCTCT
16634


668
GAUGUACA G UGAAAUCC
7266
GGATTTCA GGCTAGCTACAACGA TGTACATC
16635


673
ACAGUGAA A UCCCCGAA
7267
TTCGGGGA GGCTAGCTACAACGA TTCACTGT
16636


682
UCCCCGAA A UUAUACAC
7268
GTGTATAA GGCTAGCTACAACGA TTCGGGGA
16637


685
CCGAAAUU A UACACAUG
88
CATGTGTA GGCTAGCTACAACGA AATTTCGG
16638


687
GAAAUUAU A CACAUGAC
89
GTCATGTG GGCTAGCTACAACGA ATAATTTC
16639


689
AAUUAUAC A CAUGACUG
4291
CAGTCATG GGCTAGCTACAACGA GTATAATT
16640


691
UUAUACAC A UGACUGAA
4292
TTCAGTCA GGCTAGCTACAACGA GTGTATAA
16641


694
UACACAUG A CUGAAGGA
7269
TCCTTCAG GGCTAGCTACAACGA CATGTGTA
16642


708
GGAAGGGA G CUCGUCAU
7270
ATGACGAG GGCTAGCTACAACGA TCCCTTCC
16643


712
GGGAGCUC G UCAUUCCC
7271
GGGAATGA GGCTAGCTACAACGA GAGCTCCC
16644


715
AGCUCGUC A UUCCCUGC
4295
GCAGGGAA GGCTAGCTACAACGA GACGAGCT
16645


722
CAUUCCCU G CCGGGUUA
7272
TAACCCGG GGCTAGCTACAACGA AGGGAATG
16646


727
CCUGCCGG G UUACGUCA
7273
TGACGTAA GGCTAGCTACAACGA CCGGCAGG
16647


730
GCCGGGUU A CGUCACCU
95
AGGTGACG GGCTAGCTACAACGA AACCCGGC
16648


732
CGGGUUAC G UCACCUAA
7274
TTAGGTGA GGCTAGCTACAACGA GTAACCCG
16649


735
GUUACGUC A CCUAACAU
4300
ATGTTAGG GGCTAGCTACAACGA GACGTAAC
16650


740
GUCACCUA A CAUCACUG
7275
CAGTGATG GGCTAGCTACAACGA TAGGTGAC
16651


742
CACCUAAC A UCACUGUU
4303
AACAGTGA GGCTAGCTACAACGA GTTAGGTG
16652


745
CUAACAUC A CUGUUACU
4304
AGTAACAG GGCTAGCTACAACGA GATGTTAG
16653


748
ACAUCACU G UUACUUUA
7276
TAAAGTAA GGCTAGCTACAACQA AGTGATGT
16654


751
UCACUGUU A CUUUAAAA
100
TTTTAAAG GGCTAGCTACAACGA AACAGTGA
16655


762
UUAAAAAA G UUUCCACU
7277
AGTGGAAA GGCTAGCTACAACGA TTTTTTAA
16656


768
AAGUUUCC A CUUGACAC
4308
GTGTCAAG GGCTAGCTACAACGA GGAAACTT
16657


773
UCCACUUG A CACUUUGA
7278
TCAAAGTG GGCTAGCTACAACGA CAAGTGGA
16658


775
CACUUGAC A CUUUGAUC
4310
GATCAAAG GGCTAGCTACAACGA GTCAAGTG
16659


781
ACACUUUG A UCCCUGAU
7279
ATCAGGGA GGCTAGCTACAACGA CAAAGTGT
16660


788
GAUCCCUG A UGGAAAAC
7280
GTTTTCCA GGCTAGCTACAACGA CAGGGATC
16661


795
GAUGGAAA A CGCAUAAU
7281
ATTATGCG GGCTAGCTACAACGA TTTCCATC
16662


797
UGGAAAAC G CAUAAUCU
7282
AGATTATG GGCTAGCTACAACGA GTTTTCCA
16663


799
GAAAACGC A UAAUCUGG
4315
CCAGATTA GGCTAGCTACAACGA GCGTTTTC
16664


802
AACGCAUA A UCUGGGAC
7283
GTCCCAGA GGCTAGCTACAACGA TATGCGTT
16665


809
AAUCUGGG A CAGUAGAA
7284
TTCTACTG GGCTAGCTACAACGA CCCAGATT
16666


812
CUGGGACA G UAGAAAGG
7285
CCTTTCTA GGCTAGCTACAACGA TGTCCCAG
16667


821
UAGAAAGG C CUUCAUCA
7286
TGATGAAG GGCTAGCTACAACGA CCTTTCTA
16668


826
AGGGCUUC A UCAUAUCA
4319
TGATATGA GGCTAGCTACAACGA GAAGCCCT
16669


829
GCUUCAUC A UAUCAAAU
4320
ATTTGATA GGCTAGCTACAACGA GATGAAGC
16670


831
UUCAUCAU A UCAAAUGC
117
GCATTTGA GGCTAGCTACAACGA ATGATGAA
16671


836
CAUAUCAA A UGCAACGU
7287
ACGTTGCA GGCTAGCTACAACGA TTGATATG
16672


838
UAUCAAAU C CAACGUAC
7288
GTACGTTG GGCTAGCTACAACGA ATTTGATA
16673


841
CAAAUGCA A CGUACAAA
7289
TTTGTACG GGCTAGCTACAACGA TGCATTTG
16674


843
AAUGCAAC G UACAAAGA
7290
TCTTTGTA GGCTAGCTACAACGA GTTGCATT
16675


845
UGCAACGU A CAAAGAAA
119
TTTCTTTG GGCTAGCTACAACGA ACGTTGCA
16676


853
ACAAAGAA A UAGGGCUU
7291
AAGCCCTA GGCTAGCTACAACGA TTCTTTGT
16677


858
GAAAUAGG G CUUCUGAC
7292
GTCAGAAG GGCTAGCTACAACGA CCTATTTC
16678


865
GGCUUCUG A CCUGUGAA
7293
TTCACAGG GGCTAGCTACAACGA CAGAAGCC
16679


869
UCUGACCU G UGAAGCAA
7294
TTGCTTCA GGCTAGCTACAACGA AGGTCAGA
16680


874
CCUGUGAA C CAACAGUC
7295
GACTGTTG GGCTAGCTACAACGA TTCACAGG
16681


877
GUGAAGCA A CAGUCAAU
7296
ATTGACTG GGCTAGCTACAACGA TGCTTCAC
16682


880
AAGCAACA G UCAAUGGG
7297
CCCATTGA GGCTAGCTACAACGA TGTTGCTT
16683


884
AACAGUCA A UGGGCAUU
7298
AATGCCCA GGCTAGCTACAACGA TGACTGTT
16684


888
GUCAAUGG G CAUUUGUA
7299
TACAAATG GGCTAGCTACAACGA CCATTGAC
16685


890
CAAUGGGC A UUUGUAUA
433
UATACAAA GGCTAGCTACAACGA GCCCATTG
16686


894
GGGCAUUU G UAUAAGAC
7300
GTCTTATA GGCTAGCTACAACGA AAATGCCC
16687


896
GCAUUUGU A UAAGACAA
126
TTGTCTTA GGCTAGCTACAACGA ACAAATGC
16688


901
UGUAUAAG A CAAACUAU
7301
ATAGTTTG GGCTAGCTACAACGA CTTATACA
16689


905
UAAGACAA A CUAUCUCA
7302
TGAGATAG GGCTAGCTACAACGA TTGTCTTA
16690


908
GACAAACU A UCUCACAC
128
GTGTGAGA GGCTAGCTACAACGA AGTTTCTC
16691


913
ACUAUCUC A CACAUCCA
4335
TCGATGTG GGCTAGCTACAACGA GAGATAGT
16692


915
UAUCUCAC A CAUCGACA
4336
TGTCGATG GGCTAGCTACAACGA GTGAGATA
16693


917
UCUCACAC A UCGACAAA
4337
TTTGTCGA GGCTAGCTACAACGA GTGTGAGA
16694


921
ACACAUCG A CAAACCAA
7303
TTGGTTTG GGCTAGCTACAACGA CGATGTCT
16695


925
AUCGACAA A CCAAUACA
7304
TGTATTGG GGCTAGCTACAACGA TTGTCGAT
16696


929
ACAAACCA A UACAAUCA
7305
TGATTGTA GGCTAGCTACAACGA TGGTTTGT
16697


931
AAACCAAU A CAAUCAUA
132
TATGATTG GGCTAGCTACAACGA ATTGGTTT
16698


934
CCAAUACA A UCAUAGAU
7306
ATCTATGA GGCTAGCTACAACGA TGTATTCG
16699


937
AUACAAUC A UAGAUGUC
4342
GACATCTA GGCTAGCTACAACGA GATTGTAT
16700


941
AAUCAUAG A UGUCCAAA
7307
TTTGGACA GGCTAGCTACAACGA CTATGATT
16701


943
UCAUAGAU C UCCAAAUA
7308
TATTTGGA GGCTAGCTACAACGA ATCTATGA
16702


949
AUGUCCAA A UAAGCACA
7309
TGTCCTTA GGCTACCTACAACGA TTGGACAT
16703


953
CCAAAUAA G CACACCAC
7310
GTGGTGTG GGCTAGCTACAACGA TTATTTGG
16704


955
AAAUAAGC A CACCACGC
4345
GCGTGGTG GGCTAGCTACAACGA GCTTATTT
16705


957
AUAAGCAC A CCACGCCC
4346
GGGCGTGG GCCTAGCTACAACGA GTGCTTAT
16706


960
AGCACACC A CGCCCAGU
4348
ACTGGCCG GCCTAGCTACAACGA GGTGTGCT
16707


962
CACACCAC C CCCAGUCA
731
UGACTGGG GGCTAGCTACAACGA GTGGTGTG
16708


967
CACGCCCA C UCAAAUUA
7312
TAATTTGA GGCTAGCTACAACGA TGGGCGTG
16709


972
CCAGUCAA A UUACUUAG
7313
CTAAGTAA GGCTAGCTACAACGA TTGACTGG
16710


975
GUCAAAUU A CUUAGAGG
139
CCTCTAAG GGCTAGCTACAACGA AATTTGAC
16711


983
ACUUAGAG G CCAUACUC
7314
GAGTATGG GGCTAGCTACAACGA CTCTAAGT
16712


986
UAGAGGCC A UACUCUUG
4355
CAAGAGTA CGCTAGCTACAACGA GGCCTCTA
16713


988
GAGGCCAU A CUCUUGUC
142
GACAACAG GGCTAGCTACAACGA ATGGCCTC
16714


994
AUACUCUU G UCCUCAAU
7315
ATTGAGGA GGCTAGCTACAACGA AAGAGTAT
16715


1001
UGUCCUCA A UUGUACUG
7316
CAGTACAA GGCTAGCTACAACGA TGAGGACA
16716


1004
CCUCAAUU G UACUGCUA
7317
TACCACTA GGCTAGCTACAACGA AATTGAGG
16717


1006
UCAAUUCU A CUGCUACC
148
GGTAGCAG CGCTAGCTACAACGA ACAATTGA
16718


1009
AUUCUACU C CUACCACU
7318
AGTGGTAC GGCTAGCTACAACGA AGTACAAT
16719


1012
GUACUGCU A CCACUCCC
149
GGGAGTGG GGCTAGCTACAACGA ACCACTAC
16720


1015
CUGCUACC A CUCCCUUC
4364
CAAGGGAG GGCTAGCTACAACGA GGTAGCAG
16721


1025
UCCCUUCA A CACGAGAG
7319
CTCTCGTC CGCTAGCTACAACGA TCAACGCA
16722


1027
CCUUGAAC A CGAGAGUU
4369
AACTCTCG GGCTACCTACAACGA CTTCAAGC
16723


1033
ACACGAGA G UUCAAAUG
7320
CATTTGAA GGCTAGCTACAACGA TCTCGTGT
16724


1039
GAGUUCAA A UGACCUGG
7321
CCAGGTCA GGCTAGCTACAACGA TTGAACTC
16725


1042
UUCAAAUG A CCUGGAGU
7322
ACTCCAGG GGCTAGCTACAACGA CATTTGAA
16726


1049
GACCUGGA G UUACCCUG
7323
CAGGGTAA GGCTAGCTACAACGA TCCAGGTC
16727


1052
CUGGAGUU A CCCUGAUG
155
CATCAGGG GGCTAGCTACAACGA AACTCCAG
16728


1058
UUACCCUG A UGAAAAAA
7324
TTTTTTCA GGCTAGCTACAACGA CAGGGTAA
16729


1067
UGAAAAAA A UAAGAGAG
7325
CTCTCTTA GGCTAGCTACAACGA TTTTTTCA
16730


1075
AUAAGAGA G CUUCCGUA
7326
TACGGAA3 GGCTAGCTACAACGA TCTCTTAT
16731


1081
GAGCUUCC G UAAGGCGA
7327
TCGCCTTA GGCTAGCTACAACGA GGAAGCTC
16732


1086
UCCGUAAG G CGACGAAU
7328
ATTCGTCG GGCTAGCTACAACGA CTTACGGA
16733


1089
GUAAGGCG A CGAAUUGA
7329
TCAATTCG GGCTAGCTACAACGA CGCCTTAC
16734


1093
GGCGACGA A UUGACCAA
7330
TTGGTCAA GGCTAGCTACAACGA TCGTCGCC
16735


1097
ACGAAUUG A CCAAAGCA
733
UGCTTTGG GGCTAGCTACAACGA CAATTCGT
16736


1103
UGACCAAA G CAAUUCCC
7332
GGGAATTG GGCTAGCTACAACGA TTTGGTCA
16737


1106
CCAAAGCA A UUCCCAUG
7333
CATGGGAA GGCTAGCTACAACGA TGCTTTGG
16738


1112
CAAUUCCC A UGCCAACA
4383
TGTTGGCA GGCTAGCTACAACGA GGGAATTG
16739


1114
AUUCCCAU G CCAACAUA
7334
TATGTTGG GGCTAGCTACAACGA ATGGGAAT
16740


1118
CCAUGCCA A CAUAUUCU
7335
AGAATATG GGCTAGCTACAACGA TGGCATGG
16741


1120
AUGCCAAC A UAUUCUAC
4386
GTAGAATA GGCTAGCTACAACGA GTTGGCAT
16742


1122
GCCAACAU A UUCUACAG
163
CTGTAGAA GGCTAGCTACAACGA ATGTTGGC
16743


1127
CAUAUUCU A CAGUGUUC
166
GAACACTG GGCTAGCTACAACGA AGAATATG
16744


1130
AUUCUACA G UGUUCUUA
7336
TAAGAACA GGCTAGCTACAACGA TGTAGAAT
16745


1132
UCUACAGU G UUCUUACU
7337
AGTAAGAA GGCTAGCTACAACGA ACTGTAGA
16746


1138
GUGUUCUU A CUAUUGAC
170
GTCAATAG GGCTAGCTACAACGA AAGAACAC
16747


1141
UUCUUACU A UUGACAAA
171
UTTGTCAA GGCTAGCTACAACGA AGTAAGAA
16748


1145
UACUAUUG A CAAAAUGC
7338
GCATTTTG GGCTAGCTACAACGA CAATAGTA
16749


1150
UUGACAAA A UGCAGAAC
7339
GTTCTGCA GGCTAGCTACAACGA TTTGTCAA
16750


1152
GACAAAAU G CAGAACAA
7340
TTGTTCTG GGCTAGCTACAACGA ATTTTGTC
16751


1157
AAUGCAGA A CAAAGACA
734
UGTCTTTG GCCTAGCTACAACGA TCTGCATT
16752


1163
GAACAAAG A CAAAGGAC
7342
GTCCTTTG GGCTAGCTACAACGA CTTTGTTC
16753


1170
GACAAAGG A CUUUAUAC
7343
GTATAAAG GGCTAGCTACAACGA CCTTTGTC
16754


1175
AGGACUUU A UACUUGUC
175
GACAAGTA GGCTAGCTACAACGA AAAGTCCT
16755


1177
GACUUUAU A CUUGUCGU
176
ACGACAAG GGCTAGCTACAACGA ATAAAGTC
16756


1181
UUAUACUU G UCGUGUAA
7344
TTACACGA GGCTAGCTACAACGA AAGTATAA
16757


1184
UACUUGUC G UGUAAGGA
7345
TCCTTACA GGCTAGCTACAACGA GACAAGTA
16758


1186
CUUGUCGU G UAAGGAGU
7346
ACTCCTTA GGCTAGCTACAACGA ACGACAAG
16759


1193
UGUAAGGA G UGGACCAU
7347
ATGGTCCA GGCTAGCTACAACGA TCCTTACA
16760


1197
AGGAGUGG A CCAUCAUU
7348
AATGATGG GGCTAGCTACAACGA CCACTCCT
16761


1200
AGUGGACC A UCAUUCAA
4398
TTGAATGA GGCTAGCTACAACGA GGTCCACT
16762


1203
UGACCAUC A UUCAAAUC
4399
GATTTGAA GGCTAGCTACAACGA GATGGTCC
16763


1209
UCAUUCAA A UCUCUUAA
7349
TTAACAGA GGCTAGCTACAACGA TTGAATGA
16764


1213
UCAAAUCU G UUAACACC
7350
GGTGTTAA GGCTAGCTACAACGA AGATTTGA
16765


1217
AUCUGUUA A CACCUCAG
7351
CTGAGGTG GGCTAGCTACAACGA TAACAGAT
16766


1219
CUGUUAAC A CCUCAGUG
4402
CACTGAGG GGCTAGCTACAACGA GTTAACAG
16767


1225
ACACCUCA G UGCAUAUA
7352
TATATGCA GGCTAGCTACAACGA TGAGGTGT
16768


1227
ACCUCAGU G CAUAUAUA
7353
TATATATG GGCTAGCTACAACGA ACTGAGGT
16769


1229
CUCAGUGC A UAUAUAUG
4406
CATATATA GGCTAGCTACAACGA GCACTGAG
16770


1231
CAGUGCAU A UAUAUGAU
187
ATCATATA GGCTAGCTACAACGA ATGCACTG
16771


1233
GUGCAUAU A UAUGAUAA
188
TTATCATA GGCTAGCTACAACGA ATATGCAC
16772


1235
GCAUAUAU A UGAUAAAG
189
CTTTATCA GGCTAGCTACAACGA ATATATGC
16773


1238
UAUAUAUG A UAAAGCAU
7354
ATGCTTTA GGCTAGCTACAACGA CATATATA
16774


1243
AUGAUAAA G CAUUCAUC
7355
GATGAATG GGCTAGCTACAACGA TTTATCAT
16775


1245
GAUAAAGC A UUCAUCAC
4407
GTGATGAA GGCTAGCTACAACGA GCTTTATC
16776


1249
AAGCAUUC A UCACUGUG
4408
CACAGTGA GGCTAGCTACAACGA GAATGCTT
16777


1252
CAUUCAUC A CUGUGAAA
4409
TTTCACAG GGCTAGCTACAACGA GATGAATG
16778


1255
UCAUCACU G UGAAACAU
7356
ATGTTTCA GGCTAGCTACAACGA AGTGATGA
16779


1260
ACUGUGAA A CAUCGAAA
7357
TTTCGATG GGCTAGCTACAACGA TTCACAGT
16780


1262
UGUGAAAC A UCGAAAAC
4411
GTTTTCGA GGCTAGCTACAACGA GTTTCACA
16781


1269
CAUCGAAA A CAGCAGGU
7358
ACCTGCTG GGCTAGCTACAACGA TTTCGATG
16782


1272
CGAAAACA G CAGGUGCU
7359
AGCACCTG GGCTAGCTACAACGA TGTTTTCG
16783


1276
AACAGCAG G UGCUUGAA
7360
TTCAAGCA GGCTAGCTACAACGA CTGCTGTT
16784


1278
CAGCAGGU G CUUGAAAC
7361
GTTTCAAG GGCTAGCTACAACGA ACCTGCTG
16785


1285
UGCUUGAA A CCGUAGCU
7362
AGCTACGG GGCTAGCTACAACGA TTCAAGCA
16786


1288
UUGAAACC C UACCUGGC
7363
GCCAGCTA GGCTAGCTACAACGA GCTTTCAA
16787


1291
AAACCGUA G CUGGCAAG
7364
CTTGCCAG GGCTAGCTACAACGA TACGGTTT
16788


1295
CGUAGCUG G CAACCGCU
7365
ACCGCTTG GGCTAGCTACAACGA CAGCTACG
16789


1299
GCUGGCAA C CGGUCUUA
7366
TAAGACCG GGCTAGCTACAACGA TTGCCAGC
16790


1302
GGCAAGCG G UCUUACCG
7367
CGGTAAGA GGCTAGCTACAACGA CGCTTGCC
16791


1307
GCGGUCUU A CCGGCUCU
199
AGAGCCGG GGCTAGCTACAACGA AAGACCGC
16792


1311
UCUUACCG G CUCUCUAU
7368
ATAGAGAG GGCTAGCTACAACGA CGGTAAGA
16793


1318
GGCUCUCU A UGAAAGUG
202
CACTTTCA GGCTAGCTACAACGA AGAGAGCC
16794


1324
CUAUGAAA G UGAAGGCA
7369
TGCCTTCA GGCTAGCTACAACGA TTTCATAG
16795


1330
AAGUGAAG G CAUUUCCC
7370
GGGAAATG GGCTAGCTACAACGA CTTCACTT
16796


1332
GUGAAGGC A UUUCCCUC
4423
GAGGGAAA GGCTAGCTACAACGA GCCTTCAC
16797


1341
UUUCCCUC G CCGGAAGU
7371
ACTTCCGG GGCTAGCTACAACGA GAGGGAAA
16798


1348
CGCCGGAA C UUGUAUGG
7372
CCATACAA GGCTAGCTACAACGA TTCCGGCG
16799


1351
CGGAAGUU G UAUGGUUA
7373
TAACCATA GGCTAGCTACAACGA AACTTCCG
16800


1353
GAAGUUGU A UGGUUAAA
208
TTTAACCA GGCTAGCTACAACGA ACAACTTC
16801


1356
GUUGUAUG C UUAAAAGA
7374
TCTTTTAA GGCTAGCTACAACGA CATACAAC
16802


1364
GUUAAAAG A UGGGUUAC
7375
GTAACCCA GGCTAGCTACAACGA CTTTTAAC
16803


1368
AAAGAUGG C UUACCUGC
7376
GCAGGTAA GGCTAGCTACAACGA CCATCTTT
16804


1371
GAUGGGUU A CCUGCGAC
212
GTCGCAGG GGCTAGCTACAACGA AACCCATC
16805


1375
GGUUACCU C CCACUGAC
7377
CTCAGTCG CGCTAGCTACAACGA ACGTAACC
16806


1378
UACCUGCG A CUGAGAAA
7378
TTTCTCAC GCCTAGCTACAACGA CGCAGGTA
16807


1386
ACUGAGAA A UCUCCUCC
7379
CGAGCACA GCCTAGCTACAACGA TTCTCACT
16808


1390
AGAAAUCU C CUCCCUAU
7380
ATACCGAG GCCTAGCTACAACGA AGATTTCT
16809


1394
AUCUCCUC C CUAUUUGA
738
UCAAATAG GGCTAGCTACAACGA GAGCAGAT
16810


1397
UGCUCGCU A UUUCACUC
215
CAGTCAAA GGCTAGCTACAACGA AGCCAGCA
16811


1402
GCUAUUUC A CUCGUCCC
7382
CCCACGAG GGCTAGCTACAACGA CAAATACC
16812


1406
UUUGACUC C UGCCUACU
7383
AGTAGCCA GGCTAGCTACAACGA GAGTCAAA
16813


1409
CACUCCUC C CUACUCGU
7384
ACCAGTAC CGCTAGCTACAACGA CACGACTC
16814


1412
UCGUGCCU A CUCGUUAA
219
TTAACCAG CGCTAGCTACAACGA ACCCACCA
16815


1416
GGCUACUC C UUAAUUAU
7385
ATAATTAA GGCTAGCTACAACGA GAGTAGCC
16816


1420
ACUCGUUA A UUAUCAAG
7386
CTTGATAA GGCTAGCTACAACGA TAACGAGT
16817


1423
CGUUAAUU A UCAAGGAC
224
CTCCTTGA GGCTAGCTACAACGA AATTAACG
16818


1430
UAUCAACC A CGUAACUC
7387
CAGTTACG GCCTAGCTACAACGA CCTTCATA
16819


1432
UCAACGAC C UAACUGAA
7388
TTCAGTTA GCCTAGCTACAACGA GTCCTTCA
16820


1435
AGCACCUA A CUCAACAC
7389
CTCTTCAG CCCTACCTACAACGA TACGTCCT
16821


1445
UGAAGAGG A UGCAGGGA
7390
TCCCTGCA GGCTAGCTACAACGA CCTCTTCA
16822


1447
AAGAGGAU G CAGGGAAU
7391
ATTCCCTG GGCTAGCTACAACGA ATCCTCTT
16823


1454
UGCAGGGA A UUAUACAA
7392
TTGTATAA GGCTAGCTACAACGA TCCCTGCA
16824


1457
AGGGAAUU A UACAAUCU
228
AGATTGTA GGCTAGCTACAACGA AATTCCCT
16825


1459
GGAAUUAU A CAAUCUUG
229
CAAGATTG GGCTAGCTACAACGA ATAATTCC
16826


1462
AUUAUACA A UCUUGCUG
7393
CAGCAAGA GGCTAGCTACAACGA TGTATAAT
16827


1467
ACAAUCUU G CUGAGCAU
7394
ATGCTCAG GGCTAGCTACAACGA AAGATTGT
16828


1472
CUUGCUGA G CAUAAAAC
7395
GTTTTATG GGCTAGCTACAACGA TCAGCAAG
16829


1474
UGCUGAGC A UAAAACAG
4443
CTGTTTTA GGCTAGCTACAACGA GCTCAGCA
16830


1479
AGCAUAAA A CAGUCAAA
7396
TTTGACTG GGCTAGCTACAACGA TTTATGCT
16831


1482
AUAAAACA G UCAAAUGU
7397
ACATTTGA GGCTAGCTACAACGA TGTTTTAT
16832


1487
ACAGUCAA A UGUGUUUA
7398
TAAACACA GGCTAGCTACAACGA TTGACTGT
16833


1489
AGUCAAAU G UGUUUAAA
7399
TTTAAACA GGCTAGCTACAACGA ATTTGACT
16834


1491
UCAAAUGU G UUUAAAAA
7400
TTTTTAAA GGCTAGCTACAACGA ACATTTGA
16835


1499
GUUUAAAA A CCUCACUG
7401
CAGTGAGG GGCTAGCTACAACGA TTTTAAAC
16836


1504
AAAACCUC A CUGCCACU
4448
AGTGGCAG GGCTAGCTACAACGA GAGGTTTT
16837


1507
ACCUCACU G CCACUCUA
7402
TAGAGTGG GGCTAGCTACAACGA AGTGAGGT
16838


1510
UCACUGCC A CUCUAAUU
4451
AATTAGAG GGCTAGCTACAACGA GGCAGTGA
16839


1516
CCACUCUA A UUGUCAAU
7403
ATTGACAA GGCTAGCTACAACGA TAGAGTGG
16840


1519
CUCUAAUU G UCAAUGUG
7404
CACATTGA GGCTAGCTACAACGA AATTAGAG
16841


1523
AAUUGUCA A UGUGAAAC
7405
GTTTCACA GGCTAGCTACAACGA TGACAATT
16842


1525
UUGUCAAU G UGAAACCC
7406
GGGTTTCA GGCTAGCTACAACGA ATTGACAA
16843


1530
AAUGUGAA A CCCCAGAU
7407
ATCTGGGG GGCTAGCTACAACGA TTCACATT
16844


1537
AACCCCAG A UUUACGAA
7408
TTCGTAAA GGCTAGCTACAACGA CTGGGGTT
16845


1541
CCAGAUUU A CGAAAAGG
244
CCTTTTCG GGCTAGCTACAACGA AAATCTGG
16846


1549
ACGAAAAG G CCGUGUCA
7409
TGACACGG GGCTAGCTACAACGA CTTTTCGT
16847


1552
AAAAGGCC G UGUCAUCG
7410
CGATGACA GGCTAGCTACAACGA GGCCTTTT
16848


1554
AAGGCCGU G UCAUCGUU
7411
AACGATGA GGCTAGCTACAACGA ACGGCCTT
16849


1557
GCCGUGUC A UCGUUUCC
4460
GGAAACGA GGCTAGCTACAACGA GACACGGC
16850


1560
GUGUCAUC G UUUCCAGA
7412
TCTGGAAA GGCTAGCTACAACGA GATGACAC
16851


1568
GUUUCCAG A GCCGGCUC
7413
GAGCCGGG GGCTAGCTACAACGA CTGGAAAC
16852


1573
CAGACCCG G CUCUCUAC
7414
GTAGAGAG GGCTAGCTACAACGA CGGGTCTG
16853


1580
GGCUCUCG A CCCACUGG
252
CCAGTGGG GGCTAGCTACAACGA AGAGAGCC
16854


1584
CUCUACCC A CUGGGCAG
4470
CTGCCCAG GGCTAGCTACAACGA GGGTAGAG
16855


1589
CCCACUGG G CAGCAGAC
7415
GTCTGCTG GGCTAGCTACAACGA CCAGTGGG
16856


1592
ACUGGGCA G CAGACAAA
7416
TTTGTCTG GGCTAGCTACAACGA TGCCCAGT
16857


1596
GGCAGCAG A CAAAUCCU
7417
AGGATTTG GGCTAGCTACAACGA CTGCTGCC
16858


1600
GCAGACAA A UCCUGACU
7418
AGTCAGGA GGCTAGCTACAACGA TTGTCTGC
16859


1606
AAAUCCUG A CUUGUACC
7419
GGTACAAG GGCTAGCTACAACGA CAGGATTT
16860


1610
CCUGACUU G UACCGCAU
7420
ATGCGGTA GGCTAGCTACAACGA AAGTCAGG
16861


1612
UGACUUGU A CCGCAUAU
255
ATATGCGG GGCTAGCTACAACGA ACAAGTCA
16862


1615
CUUGUACC G CAUAUGGU
7421
ACCATATG GGCTAGCTACAACGA GGTACAAG
16863


1617
UGUACCGC A UAUGGUAU
4479
ATACCATA GGCTAGCTACAACGA GCGGTACA
16864


1619
UACCGCAU A UGGUAUCC
256
GGATACCA GGCTAGCTACAACGA ATGCCGTA
16865


1622
CGCAUAUG G UAUCCCUC
7422
GAGGGATA GGCTAGCTACAACGA CATATGCG
16866


1624
CAUAUGGU A UCCCUCAA
257
TTGAGGGA GGCTAGCTACAACGA ACCATATG
16867


1632
AUCCCUCA A CCUACAAU
7423
ATTGTAGG GGCTAGCTACAACGA TGAGGGAT
16868


1636
CUCAACCU A CAAUCAAG
260
CTTGATTG GGCTAGCTACAACGA AGGTTGAG
16869


1639
AACCUACA A UCAAGUGG
7424
CCACTTGA GGCTAGCTACAACGA TGTAGGTT
16870


1644
ACAAUCAA G UGGUUCUG
7425
CAGAACCA GGCTAGCTACAACGA TTGATTGT
16871


1647
AUCAAGUG G UUCUGGCA
7426
TGCCAGAA GGCTAGCTACAACGA CACTTGAT
16872


1653
UGGUUCUG G CACCCCUG
7427
CAGGGGTG GGCTAGCTACAACGA CAGAACCA
16873


1655
GUUCUGGC A CCCCUGUA
4489
TACAGGGG GGCTAGCTACAACGA GCCAGAAC
16874


1661
GCACCCCU G UAACCAUA
7428
TATGGTTA GGCTAGCTACAACGA AGGGGTGC
16875


1664
CCCCUGUA A CCAUAAUC
7429
GATTATGG GGCTAGCTACAACGA TACAGGGG
16876


1667
CUGUAACC A UAAUCAUU
4495
AATGATTA GGCTAGCTACAACGA GGTTACAG
16877


1670
UAACCAUA A UCAUUCCG
7430
CGGAATGA GGCTAGCTACAACGA TATGGTTA
16878


1673
CCAUAAUC A UUCCGAAG
4496
CTTCGGAA GGCTAGCTACAACGA GATTATCG
16879


1681
AUUCCGAA C CAAGGUGU
7431
ACACCTTG GGCTAGCTACAACGA TTCGGAAT
16880


1686
GAAGCAAG G UGUGACUU
7432
AAGTCACA GGCTAGCTACAACGA CTTCCTTC
16881


1688
AGCAAGGU G UGACUUUU
7433
AAAAGTCA GGCTAGCTACAACGA ACCTTGCT
16882


1691
AAGGUGUG A CUUUUGUU
7434
AACAAAAG GGCTAGCTACAACGA CACACCTT
16883


1697
UGACUUUU C UUCCAAUA
7435
TATTGGAA CGCTAGCTACAACGA AAAAGTCA
16884


1703
UUCUUCCA A UAAUGAAG
7436
CTTCATTA GGCTAGCTACAACGA TGGAACAA
16885


1706
UUCCAAUA A UGAAGAGU
7437
ACTCTTCA CGCTAGCTACAACGA TATTGCAA
16886


1713
AAUCAAGA G UCCUUUAU
7438
ATAAAGGA GGCTACCTACAACGA TCTTCATT
16887


1720
AGUCCUUU A UCCUGGAU
278
ATCCAGGA GGCTAGCTACAACGA AAAGGACT
16888


1727
UAUCCUGG A UCCUGACA
7439
TGTCAGCA GGCTAGCTACAACGA CCAGGATA
16889


1729
UCCUCGAU C CUGACAGC
7440
GCTGTCAC GGCTAGCTACAACGA ATCCACCA
16890


1733
GCAUCCUG A CACCAACA
744
UGTTCCTG CCCTAGCTACAACGA CACCATCC
16891


1736
UCCUCACA C CAACAUGC
7442
CCATCTTC CCCTACCTACAACGA TGTCAGCA
16892


1739
UGACACCA A CAUCCGAA
7443
TTCCCATC CGCTACCTACAACGA TGCTCTCA
16893


1741
ACAGCAAC A UGGCAAAC
4509
GTTTCCCA GGCTAGCTACAACGA CTTGCTGT
16894


1748
CAUGGGAA A CACAAUUG
7444
CAATTCTC CCCTACCTACAACGA TTCCCATC
16895


1753
GAAACAGA A UUGACAGC
7445
CCTCTCAA GGCTAGCTACAACGA TCTGTTTC
16896


1760
AAUUGAGA C CAUCACUC
7446
GAGTGATG CGCTACCTACAACGA TCTCAATT
16897


1762
UUGAGAGC A UCACUCAG
4511
CTCAGTGA GGCTAGCTACAACGA CCTCTCAA
16898


1765
AGAGCAUC A CUCAGCGC
4512
GCGCTCAG GGCTAGCTACAACGA CATGCTCT
16899


1770
AUCACUCA C CGCAUCGC
7447
CCCATCCG GGCTAGCTACAACGA TGAGTGAT
16900


1772
CACUCAGC G CAUGGCAA
7448
TTGCCATC CGCTAGCTACAACGA GCTGAGTG
16901


1774
CUCACCGC A UGGCAAUA
4515
TATTGCCA GCCTAGCTACAACGA GCGCTCAC
16902


1777
AGCGCAUG C CAAUAAUA
7449
TATTATTC CGCTAGCTACAACGA CATGCGCT
16903


1780
GCAUGGCA A UAAUACAA
7450
TTCTATTA GGCTAGCTACAACGA TGCCATGC
16904


1783
UGCCAAUA A UAGAACGA
745
UCCTTCTA GGCTAGCTACAACGA TATTGCCA
16905


1796
ACGAAAGA A UAAGAUGG
7452
CCATCTTA GGCTAGCTACAACGA TCTTTCCT
16906


1801
ACAAUAAC A UCCCUACC
7453
GCTACCCA GCCTAGCTACAACGA CTTATTCT
16907


1804
AUAACAUG C CUAGCACC
7454
CCTCCTAG GGCTAGCTACAACGA CATCTTAT
16908


1808
GAUGGCUA C CACCUUGG
7455
CCAAGGTG CGCTAGCTACAACGA TACCCATC
16909


1810
UCGCUAGC A CCUUCCUU
4518
AACCAAGG GGCTAGCTACAACGA GCTAGCCA
16910


1816
CCACCUUC C UUCUCCCU
7456
ACCCACAA CCCTACCTACAACGA CAACCTCC
16911


1819
CCUUCCUU C UCCCUCAC
7457
CTCACCCA CCCTACCTACAACGA AACCAACC
16912


1822
UCCUUCUC C CUCACUCU
7458
AGAGTCAC CCCTACCTACAACGA CACAACCA
16913


1826
UCUCGCUC A CUCUACAA
7459
TTCTACAG GGCTAGCTACAACGA CACCCACA
16914


1834
ACUCUACA A UUUCUCGA
7460
TCCACAAA CCCTACCTACAACGA TCTACAGT
16915


1843
UUUCUCCA A UCUACAUU
7461
AATCTAGA CGCTAGCTACAACGA TCCACAAA
16916


1847
UCCAAUCU A CAUUUCCA
295
TCCAAATC CCCTACCTACAACGA ACATTCCA
16917


1849
GAAUCUAC A UUUCCAUA
4526
TATCCAAA CCCTACCTACAACGA CTACATTC
16918


1853
CUACAUUU C CAUACCUU
7462
AACCTATC CCCTACCTACAACGA AAATCTAC
16919


1855
ACAUUUGC A UAGCUUCC
4527
GGAAGCTA GGCTAGCTACAACGA GCAAATGT
16920


1858
UUUGCAUA G CUUCCAAU
7463
ATTGGAAG GGCTAGCTACAACGA TATGCAAA
16921


1865
AGCUUCCA A UAAAGUUG
7464
CAACTTTA GGCTAGCTACAACGA TGGAAGCT
16922


1870
CCAAUAAA G UUGGGACU
7465
AGTCCCAA GGCTAGCTACAACGA TTTATTGG
16923


1876
AAGUUGGG A CUGUGGGA
7466
TCCCACAG GGCTAGCTACAACGA CCCAACTT
16924


1879
UUGGGACU G UGGGAAGA
7467
TCTTCCCA GGCTAGCTACAACGA AGTCCCAA
16925


1889
GGGAAGAA A CAUAAGCU
7468
AGCTTATG GGCTAGCTACAACGA TTCTTCCC
16926


1891
GAAGAAAC A UAAGCUUU
4532
AAAGCTTA GGCTAGCTACAACGA GTTTCTTC
16927


1895
AAACAUAA G CUUUUAUA
7469
TATAAAAG GGCTAGCTACAACGA TTATGTTT
16928


1901
AAGCUUUU A UAUCACAG
307
CTGTGATA GGCTAGCTACAACGA AAAAGCTT
16929


1903
GCUUUUAU A UCACAGAU
308
ATCTGTGA GGCTAGCTACAACGA ATAAAAGC
16930


1906
UUUAUAUC A CAGAUGUG
4534
CACATCTG GGCTAGCTACAACGA GATATAAA
16931


1910
UAUCACAG A UGUGCCAA
7470
TTGGCACA GGCTAGCTACAACGA CTGTGATA
16932


1912
UCACAGAU G UGCCAAAU
7471
ATTTGGCA GGCTAGCTACAACGA ATCTGTGA
16933


1914
ACAGAUGU G CCAAAUGG
7472
CCATTTGG GGCTAGCTACAACGA ACATCTGT
16934


1919
UGUGCCAA A UGGGUUUC
7473
GAAACCCA GGCTAGCTACAACGA TTGGCACA
16935


1923
CCAAAUGG G UUUCAUGU
7474
ACATGAAA GGCTAGCTACAACGA CCATTTGG
16936


1928
UGGGUUUC A UGUUAACU
4538
AGTTAACA GGCTAGCTACAACGA GAAACCCA
16937


1930
GGUUUCAU G UUAACUUG
7475
CAAGTTAA GGCTAGCTACAACGA ATGAAACC
16938


1934
UCAUGUUA A CUUGGAAA
7476
TTTCCAAG GGCTAGCTACAACGA TAACATGA
16939


1945
UGGAAAAA A UGCCGACG
7477
CGTCGGCA GGCTAGCTACAACGA TTTTTCCA
16940


1947
GAAAAAAU G CCGACGGA
7478
TCCGTCGG GGCTAGCTACAACGA ATTTTTTC
16941


1951
AAAUGCCG A CGGAAGGA
7479
TCCTTCCG GGCTAGCTACAACGA CGGCATTT
16942


1964
AGGAGAGG A CCUGAAAC
7480
GTTTCAGG GGCTAGCTACAACGA CCTCTCCT
16943


1971
GACCUGAA A CUGUCUUG
7481
CAAGACAG GGCTAGCTACAACGA TTCAGGTC
16944


1974
CUGAAACU G UCUUGCAC
7482
GTGCAAGA GGCTAGCTACAACGA AGTTTCAG
16945


1979
ACUGUCUU G CACAGUUA
7483
TAACTGTG GGCTAGCTACAACGA AAGACAGT
16946


1981
UGUCUUGC A CAGUUAAC
4545
GTTAACTG GGCTAGCTACAACGA GCAAGACA
16947


1984
CUUGCACA G UUAACAAG
7484
CTTGTTAA GGCTAGCTACAACGA TGTGCAAG
16948


1988
CACAGUUA A CAAGUUCU
7485
AGAACTTG GGCTAGCTACAACGA TAACTGTG
16949


1992
GUUAACAA G UUCUUAUA
7486
TATAAGAA GGCTAGCTACAACGA TTGTTAAC
16950


1998
AAGUUCUU A UACAGAGA
323
TCTCTGTA GGCTAGCTACAACGA AAGAACTT
16951


2000
GUUCUUAU A CAGAGACG
324
CGTCTCTG GGCTAGCTACAACGA ATAAGAAC
16952


2006
AUACAGAG A CGUUACUU
7487
AAGTAACG GGCTAGCTACAACGA CTCTGTAT
16953


2008
ACAGAGAC G UUACUUGG
7488
CCAAGTAA GGCTAGCTACAACGA GTCTCTGT
16954


2011
GAGACGUU A CUUGGAUU
326
AATCCAAG GGCTAGCTACAACGA AACGTCTC
16955


2017
UUACUUGG A UUUUACUG
7489
CAGTAAAA GGCTAGCTACAACGA CCAAGTAA
16956


2022
UGGAUUUU A CUGCGGAC
331
GTCCGCAG GGCTAGCTACAACGA AAAATCCA
16957


2025
AUUUUACU G CGGACAGU
7490
ACTGTCCG GGCTAGCTACAACGA AGTAAAAT
16958


2029
UACUGCGG A CAGUUAAU
7491
ATTAACTG GGCTAGCTACAACGA CCGCAGTA
16959


2032
UGCGGACA G UUAAUAAC
7492
GTTATTAA GGCTAGCTACAACGA TGTCCGCA
16960


2036
GACAGUUA A UAACAGAA
7493
TTCTGTTA GGCTAGCTACAACGA TAACTGTC
16961


2039
AGUUAAUA A CAGAACAA
7494
TTGTTCTG GGCTAGCTACAACGA TATTAACT
16962


2044
AUAACAGA A CAAUGCAC
7495
GTGCATTG GGCTAGCTACAACGA TCTGTTAT
16963


2047
ACAGAACA A UGCACUAC
7496
GTAGTGCA GGCTAGCTACAACGA TGTTCTGT
16964


2049
AGAACAAU G CACUACAG
7497
CTGTAGTG GGCTAGCTACAACGA ATTGTTCT
16965


2051
AACAAUGC A CUACAGUA
4555
TACTGTAG GGCTAGCTACAACGA GCATTGTT
16966


2054
AAUGCACU A CAGUAUUA
335
TAATACTG GGCTAGCTACAACGA AGTGCATT
16967


2057
GCACUACA G UAUUAGCA
7498
TGCTAATA GGCTAGCTACAACGA TGTAGTGC
16968


2059
ACUACAGU A UUAGCAAG
336
CTTGCTAA GGCTAGCTACAACGA ACTGTAGT
16969


2063
CAGUAUUA G CAAGCAAA
7499
TTTGCTTG GGCTAGCTACAACGA TAATACTG
16970


2067
AUUAGCAA G CAAAAAAU
7500
ATTTTTTG GGCTAGCTACAACGA TTGCTAAT
16971


2074
AGCAAAAA A UGGCCAUC
7501
GATGGCCA GGCTAGCTACAACGA TTTTTGCT
16972


2077
AAAAAAUG G CCAUCACU
7502
AGTGATGG GGCTAGCTACAACGA CATTTTTT
16973


2080
AAAUGGCC A UCACUAAG
4561
CTTAGTGA GGCTAGCTACAACGA GGCCATTT
16974


2083
UGGCCAUC A CUAAGGAG
4562
CTCCTTAG GGCTAGCTACAACGA GATGGCCA
16975


2091
ACUAAGGA G CACUCCAU
7503
ATGGAGTG GGCTAGCTACAACGA TCCTTAGT
16976


2093
UAAGGAGC A CUCCAUCA
4564
TGATGGAG GGCTAGCTACAACGA GCTCCTTA
16977


2098
AGCACUCC A UCACUCUU
4567
AAGAGTGA GGCTAGCTACAACGA GGAGTGCT
16978


2101
ACUCCAUC A CUCUUAAU
4568
ATTAAGAG GGCTAGCTACAACGA GATGGAGT
16979


2108
CACUCUUA A UCUUACCA
7504
TGGTAAGA GGCTAGCTACAACGA TAAGAGTG
16980


2113
UUAAUCUU A CCAUCAUG
348
CATGATGG GGCTAGCTACAACGA AAGATTAA
16981


2116
AUCUUACC A UCAUGAAU
4573
ATTCATGA GGCTAGCTACAACGA GGTAAGAT
16982


2119
UUACCAUC A UGAAUGUU
4574
AACATTCA GGCTAGCTACAACGA GATGGTAA
16983


2123
CAUCAUGA A UGUUUCCC
7505
GGGAAACA GGCTAGCTACAACGA TCATGATG
16984


2125
UCAUGAAU C UUUCCCUG
7506
CAGGGAAA GGCTAGCTACAACGA ATTCATGA
16985


2133
GUUUCCCU C CAAGAUUC
7507
GAATCTTG GGCTAGCTACAACGA AGGGAAAC
16986


2138
CCUGCAAG A UUCAGGCA
7508
TGCCTGAA GGCTAGCTACAACGA CTTGCAGG
16987


2144
AGAUUCAG G CACCUAUG
7509
CATAGGTG GGCTAGCTACAACGA CTGAATCT
16988


2146
AUUCAGGC A CCUAUGCC
4580
GGCATAGG GCCTAGCTACAACGA GCCTGAAT
16989


2150
AGGCACCU A UGCCUGCA
355
TGCAGGCA GGCTAGCTACAACGA AGGTGCCT
16990


2152
GCACCUAU G CCUGCAGA
7510
TCTCCAGG GGCTAGCTACAACGA ATACGTCC
16991


2156
CUAUGCCU G CAGAGCCA
751
UGGCTCTG GGCTAGCTACAACGA AGGCATAG
16992


2161
CCUGCAGA G CCAGGAAU
7512
ATTCCTGC CCCTAGCTACAACGA TCTGCAGG
16993


2168
ACCCAGGA A UGUAUACA
7513
TGTATACA GGCTAGCTACAACGA TCCTGGCT
16994


2170
CCAGGAAU G UAUACACA
7514
TGTGTATA GGCTAGCTACAACGA ATTCCTGG
16995


2172
AGGAAUGU A UACACAGG
356
CCTGTGTA GGCTAGCTACAACGA ACATTCCT
16996


2174
GAAUGUAU A CACAGCGG
357
CCCCTCTG GGCTAGCTACAACGA ATACATTC
16997


2176
AUGUAUAC A CAGGGGAA
4588
TTCCCCTG GGCTAGCTACAACGA GTATACAT
16998


2188
GGGAAGAA A UCCUCCAG
7515
CTGGAGGA GGCTAGCTACAACGA TTCTTCCC
16999


2206
AGAAAGAA A UUACAAUC
7516
GATTGTAA GGCTAGCTACAACGA TTCTTTCT
17000


2209
AAGAAAUU A CAAUCAGA
36
UCTGATTG GGCTAGCTACAACGA AATTTCTT
17001


2212
AAAUUACA A UCAGAGAU
7517
ATCTCTGA GGCTAGCTACAACGA TGTAATTT
17002


2219
AAUCAGAG A UCAGGAAG
7518
CTTCCTGA GGCTAGCTACAACGA CTCTGATT
17003


2227
AUCAGGAA C CACCAUAC
7519
GTATGGTG GGCTAGCTACAACGA TTCCTCAT
17004


2229
CAGGAACC A CCAUACCU
4597
AGCTATGG GGCTAGCTACAACGA GCTTCCTG
17005


2232
GAAGCACC A UACCUCCU
4599
AGGACGTA CGCTAGCTACAACGA GGTGCTTC
17006


2234
AGCACCAU A CCUCCUGC
364
GCAGGAGG GGCTAGCTACAACGA ATGGTGCT
17007


2241
UACCUCCU C CGAAACCU
7520
AGGTTTCG GGCTACCTACAACGA ACCAGGTA
17008


2246
CCUGCGAA A CCUCAGUG
7521
CACTGAGG GGCTAGCTACAACGA TTCGCACG
17009


2252
AAACCUCA G UGAUCACA
7522
TGTCATCA GGCTAGCTACAACGA TGAGGTTT
17010


2255
CCUCAGUG A UCACACAG
7523
CTGTGTGA CGCTAGCTACAACGA CACTCAGG
17011


2258
CAGUGAUC A CACAGUGG
4607
CCACTGTG GGCTAGCTACAACGA GATCACTC
17012


2260
GUGAUCAC A CACUGCCC
4608
GGCCACTG CCCTAGCTACAACGA GTGATCAC
17013


2263
AUCACACA G UGGCCAUC
7524
GATCGCCA GCCTAGCTACAACGA TGTGTGAT
17014


2266
ACACAGUG G CCAUCAGC
7525
GCTGATCG CGCTAGCTACAACGA CACTGTCT
17015


2269
CAGUGGCC A UCAGCAGU
4611
ACTGCTCA GGCTAGCTACAACGA GCCCACTG
17016


2273
GGCCAUCA G CAGUUCCA
7526
TGCAACTG GGCTAGCTACAACGA TGATGGCC
17017


2276
CAUCAGCA G UUCCACCA
7527
TGGTGGAA GGCTAGCTACAACGA TGCTGATG
17018


2281
GCAGUUCC A CCACUUUA
4615
TAAAGTGG GGCTAGCTACAACGA GGAACTCC
17019


2284
GUUCCACC A CUUUAGAC
4617
GTCTAAAG GGCTAGCTACAACGA GGTGGAAC
17020


2291
CACUUUAG A CUGUCAUG
7528
CATGACAG GGCTAGCTACAACGA CTAAAGTG
17021


2294
UUUAGACU G UCAUGCUA
7529
TAGCATGA GGCTAGCTACAACGA AGTCTAAA
17022


2297
AGACUGUC A UGCUAAUG
4620
CATTAGCA GGCTAGCTACAACGA GACAGTCT
17023


2299
ACUGUCAU G CUAAUGGU
7530
ACCATTAG GGCTAGCTACAACGA ATGACAGT
17024


2303
UCAUGCUA A UGGUGUCC
7531
GGACACCA GGCTAGCTACAACGA TAGCATGA
17025


2306
UGCUAAUG G UGUCCCCG
7532
CGGGGACA GGCTAGCTACAACGA CATTAGCA
17026


2308
CUAAUGGU G UCCCCGAG
7533
CTCGGGGA GGCTAGCTACAACGA ACCATTAG
17027


2316
GUCCCCGA G CCUCAGAU
7534
ATCTGAGG GGCTAGCTACAACGA TCGGGGAC
17028


2323
AGCCUCAG A UCACUUGG
7535
CCAAGTGA GGCTAGCTACAACGA CTGAGGCT
17029


2326
CUCAGAUC A CUUGGUUU
4628
AAACCAAG GGCTAGCTACAACGA GATCTGAG
17030


2331
AUCACUUG C UUUAAAAA
7536
TTTTTAAA GGCTAGCTACAACGA CAAGTGAT
17031


2339
GUUUAAAA A CAACCACA
7537
TGTGGTTG GGCTAGCTACAACGA TTTTAAAC
17032


2342
UAAAAACA A CCACAAAA
7538
TTTTGTGG GGCTAGCTACAACGA TGTTTTTA
17033


2345
AAACAACC A CAAAAUAC
4632
GTATTTTG GGCTAGCTACAACGA GGTTGTTT
17034


2350
ACCACAAA A UACAACAA
7539
TTGTTGTA GGCTAGCTACAACGA TTTGTGGT
17035


2352
CACAAAAU A CAACAAGA
383
TCTTGTTG GGCTAGCTACAACGA ATTTTGTG
17036


2355
AAAAUACA A CAAGAGCC
7540
GGCTCTTG GGCTAGCTACAACGA TGTATTTT
17037


2361
CAACAAGA G CCUGGAAU
7541
ATTCCAGG GGCTAGCTACAACGA TCTTGTTG
17038


2368
AGCCUGGA A UUAUUUUA
7542
TAAAATAA GGCTAGCTACAACGA TCCAGGCT
17039


2371
CUGGAAUU A UUUUAGGA
385
TCCTAAAA GGCTAGCTACAACGA AATTCCAG
17040


2379
AUUUUAGG A CCAGGAAG
7543
CTTCCTGG GGCTAGCTACAACGA CCTAAAAT
17041


2387
ACCAGGAA G CAGCACGC
7544
GCGTGCTG GGCTAGCTACAACGA TTCCTGGT
17042


2390
AGGAAGCA G CACGCUGU
7545
ACAGCGTG GGCTAGCTACAACGA TGCTTCCT
17043


2392
GAAGCAGC A CGCUGUUU
4641
AAACAGCG GGCTAGCTACAACGA GCTGCTTC
17044


2394
AGCAGCAC G CUGUUUAU
7546
ATAAACAG GGCTAGCTACAACGA GTGCTGCT
17045


2397
AGCACGCU G UUUAUUGA
7547
TCAATAAA GGCTAGCTACAACGA AGCGTGCT
17046


2401
CGCUGUUU A UUGAAAGA
392
TCTTTCAA GGCTAGCTACAACGA AAACAGCG
17047


2410
UUGAAAGA G UCACAGAA
7548
TTCTGTGA GGCTAGCTACAACGA TCTTTCAA
17048


2413
AAAGAGUC A CAGAAGAG
4643
CTCTTCTG GGCTAGCTACAACGA GACTCTTT
17049


2423
AGAAGAGG A UGAAGGUG
7549
CACCTTCA GGCTAGCTACAACGA CCTCTTCT
17050


2429
GGAUGAAG G UGUCUAUC
7550
GATAGACA GGCTAGCTACAACGA CTTCATCC
17051


2431
AUGAAGGU G UCUAUCAC
7551
GTGATAGA GGCTAGCTACAACGA ACCTTCAT
17052


2435
AGGUGUCU A UCACUGCA
396
TGCAGTGA GGCTAGCTACAACGA AGACACCT
17053


2438
UGUCUAUC A CUGCAAAG
4646
CTTTGCAG GGCTAGCTACAACGA GATAGACA
17054


2441
CUAUCACU G CAAAGCCA
7552
TGGCTTTG GGCTAGCTACAACGA AGTGATAG
17055


2446
ACUGCAAA G CCACCAAC
7553
GTTGGTGG GGCTAGCTACAACGA TTTGCAGT
17056


2449
GCAAAGCC A CCAACCAG
4650
CTGGTTGG GGCTAGCTACAACGA GGCTTTGC
17057


2453
AGCCACCA A CCAGAAGG
7554
CCTTCTGG GGCTAGCTACAACGA TGGTGGCT
17058


2462
CCAGAAGG G CUCUGUGG
7555
CCACAGAG GGCTAGCTACAACGA CCTTCTGG
17059


2467
AGGGCUCU C UGGAAAGU
7556
ACTTTCCA GGCTAGCTACAACGA AGAGCCCT
17060


2474
UGUGGAAA G UUCAGCAU
7557
ATGCTGAA GGCTAGCTACAACGA TTTCCACA
17061


2479
AAAGUUCA C CAUACCUC
7558
GAGGTATG GGCTAGCTACAACGA TGAACTTT
17062


2481
AGUUCAGC A UACCUCAC
4658
GTGAGGTA GGCTAGCTACAACGA GCTGAACT
17063


2483
UUCAGCAU A CCUCACUG
401
CAGTGAGG GGCTAGCTACAACGA ATGCTGAA
17064


2488
CAUACCUC A CUGUUCAA
466
UTGAACAG GGCTAGCTACAACGA GAGGTATG
17065


2491
ACCUCACU C UUCAAGGA
7559
TCCTTGAA GGCTAGCTACAACGA AGTGAGGT
17066


2500
UUCAAGGA A CCUCGGAC
7560
GTCCGAGG GGCTAGCTACAACGA TCCTTGAA
17067


2507
AACCUCGG A CAAGUCUA
756
UAGACTTG GGCTAGCTACAACGA CCGAGGTT
17068


2511
UCGGACAA G UCUAAUCU
7562
AGATTAGA GGCTAGCTACAACGA TTGTCCGA
17069


2516
CAAGUCUA A UCUGGAGC
7563
GCTCCAGA GGCTAGCTACAACGA TAGACTTG
17070


2523
AAUCUGGA G CUGAUCAC
7564
GTGATCAG GGCTAGCTACAACGA TCCAGATT
17071


2527
UGGAGCUG A UCACUCUA
7565
TAGAGTGA GGCTAGCTACAACGA CAGCTCCA
17072


2530
AGCUGAUC A CUCUAACA
4670
TGTTAGAG GGCTAGCTACAACGA GATCAGCT
17073


2536
UCACUCUA A CAUGCACC
7566
GGTGCATG GGCTAGCTACAACGA TAGAGTGA
17074


2538
ACUCUAAC A UGCACCUG
4673
CAGGTGCA GGCTAGCTACAACGA GTTAGAGT
17075


2540
UCUAACAU G CACCUGUG
7567
CACAGGTG GGCTAGCTACAACGA ATGTTAGA
17076


2542
UAACAUGC A CCUGUGUG
4674
CACACAGG GGCTAGCTACAACGA GCATGTTA
17077


2546
AUGCACCU G UGUGGCUG
7568
CAGCCACA GGCTAGCTACAACGA AGGTGCAT
17078


2548
GCACCUGU C UGGCUGCG
7569
CGCAGCCA GGCTAGCTACAACGA ACAGGTGC
17079


2551
GCUGUGUG C CUGCGACU
7570
AGTCGCAG GGCTAGCTACAACGA CACACAGG
17080


2554
GUGUGGCU G CGACUCUC
7571
GAGAGTCG GGCTAGCTACAACGA AGCCACAC
17081


2557
UGGCUGCG A CUCUCUUC
7572
GAAGACAG GGCTAGCTACAACGA CGCAGCCA
17082


2568
CUCCUCUG G CUCCUAUU
7573
AATAGGAG GGCTAGCTACAACGA CAGAAGAG
17083


2574
UGGCUCCU A UUAACCCU
417
AGGGTTAA GGCTAGCTACAACGA AGGAGCCA
17084


2578
UCCUAUUA A CCCUCCUU
7574
AAGGAGGG GGCTAGCTACAACGA TAATAGGA
17085


2587
CCCUCCUU A UCCGAAAA
422
TTTTCGGA GGCTAGCTACAACGA AAGGAGGG
17086


2596
UCCGAAAA A UGAAAAGG
7575
CCTTTTCA GGCTAGCTACAACGA TTTTCGGA
17087


2604
AUGAAAAC G UCUUCUUC
7576
GAAGAAGA GGCTAGCTACAACGA CTTTTCAT
17088


2617
CUUCUGAA A UAAAGACU
7577
AGTCTTTA GGCTAGCTACAACGA TTCAGAAG
17089


2623
AAAUAAAG A CUGACUAC
7578
GTAGTCAG GGCTAGCTACAACGA CTTTATTT
17090


2627
AAAGACUG A CUACCUAU
7579
ATAGGTAG GGCTAGCTACAACGA CAGTCTTT
17091


2630
GACUGACU A CCUAUCAA
430
TTGATAGG GGCTAGCTACAACGA AGTCAGTC
17092


2634
GACUACCU A UCAAUUAU
431
ATAATTGA GGCTAGCTACAACGA AGGTAGTC
17093


2638
ACCUAUCA A UUAUAAUG
7580
CATTATAA GGCTAGCTACAACGA TGATAGGT
17094


2641
UAUCAAUU A UAAUGGAC
434
GTCCATTA GGCTAGCTACAACGA AATTGATA
17095


2644
CAAUUAUA A UGGACCCA
758
UGGGTCCA GGCTAGCTACAACGA TATAATTG
17096


2648
UAUAAUGG A CCCAGAUG
7582
CATCTGGG GGCTAGCTACAACGA CCATTATA
17097


2654
GGACCCAG A UGAAGUUC
7583
GAACTTCA GGCTAGCTACAACGA CTGGGTCC
17098


2659
CAGAUGAA C UUCCUUUG
7584
CAAAGGAA GGCTAGCTACAACGA TTCATCTG
17099


2669
UCCUUUGC A UGAGCAGU
7585
ACTGCTCA GGCTAGCTACAACGA CCAAAGGA
17100


2673
UUGGAUGA G CAGUGUGA
7586
TCACACTG GGCTAGCTACAACGA TCATCCAA
17101


2676
GAUGAGCA G UGUGAGCG
7587
CGCTCACA GGCTAGCTACAACGA TGCTCATC
17102


2678
UGAGCAGU G UGAGCGGC
7588
GCCGCTCA GGCTAGCTACAACGA ACTGCTCA
17103


2682
CAGUGUGA G CGGCUCCC
7589
GGGAGCCG GGCTAGCTACAACGA TCACACTG
17104


2685
UGUGAGCG G CUCCCUUA
7590
TAAGGCAG GGCTAGCTACAACGA CGCTCACA
17105


2693
GCUCCCUU A UGAUGCCA
442
TGGCATCA GGCTAGCTACAACGA AAGGGAGC
17106


2696
CCCUUAUG A UGCCAGCA
759
UGCTGGCA GGCTAGCTACAACGA CATAAGGG
17107


2698
CUUAUGAU G CCAGCAAG
7592
CTTGCTGG GGCTAGCTACAACGA ATCATAAG
17108


2702
UGAUGCCA C CAAGUGGG
7593
CCCACTTG GGCTAGCTACAACGA TGGCATCA
17109


2706
GCCAGCAA G UGGGAGUU
7594
AACTCCCA GGCTAGCTACAACGA TTGCTGGC
17110


2712
AAGUGGGA G UUUGCCCG
7595
CGGGCAAA GGCTAGCTACAACGA TCCCACTT
17111


2716
CGGAGUUU C CCCGGGAC
7596
CTCCCGGG GGCTAGCTACAACGA AAACTCCC
17112


2727
CGCGAGAG A CUUAAACU
7597
AGTTTAAG GGCTAGCTACAACGA CTCTCCCG
17113


2733
AGACUUAA A CUGGGCAA
7598
TTGCCCAG GGCTAGCTACAACGA TTAAGTCT
17114


2738
UAAACUGG C CAAAUCAC
7599
CTGATTTG GGCTAGCTACAACGA CCAGTTTA
17115


2742
CUGGGCAA A UCACUUGG
7600
CCAAGTGA GGCTAGCTACAACGA TTGCCCAG
17116


2745
GGCAAAUC A CUUGGAAG
4717
CTTCCAAG GGCTAGCTACAACGA GATTTGCC
17117


2758
GAAGAGGG G CUUUUGGA
760
UCCAAAAG GGCTAGCTACAACGA CCCTCTTC
17118


2770
UUGGAAAA G UGGUUCAA
7602
TTGAACCA GGCTAGCTACAACGA TTTTCCAA
17119


2773
GAAAAGUG G UUCAAGCA
7603
TGCTTGAA GGCTAGCTACAACGA CACTTTTC
17120


2779
UGGUUCAA G CAUCAGCA
7604
TGCTGATG GGCTAGCTACAACGA TTGAACCA
17121


2781
GUUCAAGC A UCAGCAUU
4721
AATGCTGA GGCTAGCTACAACGA GCTTGAAC
17122


2785
AAGCAUCA G CAUUUGGC
7605
GCCAAATG GGCTAGCTACAACGA TGATGCTT
17123


2787
GCAUCAGC A UUUGGCAU
4723
ATGCCAAA GGCTAGCTACAACGA GCTGATGC
17124


2792
AGCAUUUG G CAUUAAGA
7606
TCTTAATG GGCTAGCTACAACGA CAAATGCT
17125


2794
CAUUUGGC A UUAAGAAA
4724
TTTCTTAA GGCTAGCTACAACGA GCCAAATG
17126


2802
AUUAAGAA A UCACCUAC
7607
GTAGGTGA GGCTAGCTACAACGA TTCTTAAT
17127


2805
AAGAAAUC A CCUACGUG
4725
CACGTAGG GGCTAGCTACAACGA GATTTCTT
17128


2809
AAUCACCU A CGUGCCGG
460
CCGGCACG GGCTAGCTACAACGA AGGTGATT
17129


2811
UCACCUAC C UCCCGCAC
7608
CTCCGGCA GGCTAGCTACAACGA GTAGGTGA
17130


2813
ACCUACGU C CCGGACUG
7609
CAGTCCGG GGCTAGCTACAACGA ACGTAGGT
17131


2818
CGUCCCGC A CUGUGGCU
7610
AGCCACAG GGCTACCTACAACGA CCCCCACG
17132


2821
CCCCCACU C UGGCUGUG
7611
CACAGCCA GGCTAGCTACAACGA AGTCCGGC
17133


2824
GGACUCUG G CUGUCAAA
7612
TTTCACAG GGCTAGCTACAACGA CACAGTCC
17134


2827
CUGUGGCU G UGAAAAUG
7613
CATTTTCA GGCTAGCTACAACGA AGCCACAG
17135


2833
CUCUCAAA A UCCUCAAA
7614
TTTCACCA CGCTACCTACAACGA TTTCACAG
17136


2835
GUGAAAAU G CUGAAACA
7615
TCTTTCAG GGCTAGCTACAACGA ATTTTCAC
17137


2848
AACAGGGC G CCACGGCC
7616
GGCCCTGG GGCTACCTACAACGA CCCCTCTT
17138


2851
AGGGCGCC A CCCCCAGC
4733
GCTGCCCC GGCTACCTACAACGA CCCCCCCT
17139


2854
GCCCCACC G CCAGCGAG
7617
CTCGCTCG GGCTAGCTACAACGA CGTCGCCC
17140


2858
CACCCCCA G CGACUACA
7618
TGTACTCC GGCTACCTACAACGA TCCCCCTG
17141


2862
GCCAGCGA G UACAAACC
7619
GCTTTGTA GCCTAGCTACAACGA TCCCTCGC
17142


2864
CAGCGAGU A CAAAGCUC
461
GAGCTTTC GGCTAGCTACAACGA ACTCCCTC
17143


2869
ACUACAAA C CUCUGAUC
7620
CATCAGAC GGCTACCTACAACGA TTTCTACT
17144


2875
AACCUCUG A UGACUGAC
7621
CTCAGTCA GCCTAGCTACAACGA CACACCTT
17145


2878
CUCUGAUG A CUGACCUA
7622
TACCTCAG GGCTAGCTACAACGA CATCAGAC
17146


2883
AUGACUGA C CUAAAAAU
7623
ATTTTTAG GGCTAGCTACAACGA TCAGTCAT
17147


2890
AGCUAAAA A UCUUGACC
7624
CCTCAACA GCCTAGCTACAACGA TTTTAGCT
17148


2896
AAAUCUUG A CCCACAUU
7625
AATGTGGG GCCTAGCTACAACGA CAAGATTT
17149


2900
CUUGACCC A CAUUGGCC
4744
GGCCAATG GGCTAGCTACAACGA GGGTCAAG
17150


2902
UCACCCAC A UUGGCCAC
4745
GTCCCCAA GGCTAGCTACAACGA GTGGGTCA
17151


2906
CCACAUUG C CCACCAUC
7626
CATCGTGG GGCTACCTACAACGA CAATGTGG
17152


2909
CAUUCGCC A CCAUCUGA
4747
TCACATGC CCCTAGCTACAACGA CCCCAATG
17153


2912
UCGCCACC A UCUGAACG
4749
CGTTCAGA GCCTAGCTACAACGA GGTGGCCA
17154


2918
CCAUCUGA A CGUGCUUA
7627
TAACCACG CCCTAGCTACAACGA TCAGATGG
17155


2920
AUCUGAAC C UCCUUAAC
7628
CTTAACCA GGCTACCTACAACGA GTTCACAT
17156


2923
UGAACGUG C UUAACCUG
7629
CAGGTTAA GGCTAGCTACAACGA CACGTTCA
17157


2927
CCUCCUUA A CCUCCUCC
7630
CCAGCACC CGCTACCTACAACGA TAACCACC
17158


2931
GUUAACCU C CUCCGACC
7631
GCTCCCAC GGCTAGCTACAACGA AGCTTAAC
17159


2938
UCCUCCCA C CCUGCACC
7632
CCTCCACG CCCTACCTACAACGA TCCCACCA
17160


2942
CCCACCCU C CACCAAGC
7633
GCTTCCTG CGCTAGCTACAACGA AGGCTCCC
17161


2944
CACCCUCC A CCAAGCAA
4756
TTGCTTCG GCCTAGCTACAACGA GCAGGCTC
17162


2949
UCCACCAA C CAAGGACG
7634
CCTCCTTG CGCTAGCTACAACGA TTCCTCCA
17163


2958
CAAGCACG C CCUCUCAU
7635
ATCAGACC CCCTACCTACAACGA CCTCCTTC
17164


2965
GGCCUCUG A UGGUGAUU
7636
AATCACCA GGCTAGCTACAACGA CAGAGGCC
17165


2968
CUCUGAUG G UGAUUGUU
7637
AACAATCA GGCTAGCTACAACGA CATCAGAG
17166


2971
UGAUGGUG A UUGUUGAA
7638
TTCAACAA GGCTAGCTACAACGA CACCATCA
17167


2974
UGGUGAUU G UUGAAUAC
7639
GTATTCAA GGCTAGCTACAACGA AATCACCA
17168


2979
AUUGUUGA A UACUGCAA
7640
TTGCAGTA GGCTAGCTACAACGA TCAACAAT
17169


2981
UGUUGAAU A CUGCAAAU
473
ATTTGCAG GGCTAGCTACAACGA ATTCAACA
17170


2984
UGAAUACU G CAAAUAUG
7641
CATATTTG GGCTAGCTACAACGA AGTATTCA
17171


2988
UACUGCAA A UAUGGAAA
7642
TTTCCATA GGCTAGCTACAACGA TTGCAGTA
17172


2990
CUGCAAAU A UGGAAAUC
474
GATTTCCA GGCTAGCTACAACGA ATTTGCAG
17173


2996
AUAUGGAA A UCUCUCCA
7643
TGGAGAGA GGCTAGCTACAACGA TTCCATAT
17174


3005
UCUCUCCA A CUACCUCA
7644
TGAGGTAG GGCTAGCTACAACGA TGGAGAGA
17175


3008
CUCCAACU A CCUCAAGA
478
TCTTGAGG GGCTAGCTACAACGA AGTTGGAG
17176


3017
CCUCAAGA G CAAACGUG
7645
CACGTTTG GGCTAGCTACAACGA TCTTGAGG
17177


3021
AAGAGCAA A CGUGACUU
7646
AAGTCACG GGCTAGCTACAACGA TTGCTCTT
17178


3023
GAGCAAAC G UGACUUAU
7647
ATAAGTCA GGCTAGCTACAACGA GTTTGCTC
17179


3026
CAAACGUG A CUUAUUUU
7648
AAAATAAG GGCTAGCTACAACGA CACGTTTG
17180


3030
CGUGACUU A UUUUUUCU
481
AGAAAAAA GGCTAGCTACAACGA AAGTCACG
17181


3041
UUUUCUCA A CAAGGAUG
7649
CATCCTTG GGCTAGCTACAACGA TGAGAAAA
17182


3047
CAACAAGG A UGCAGCAC
7650
GTGCTGCA GGCTAGCTACAACGA CCTTGTTG
17183


3049
ACAAGGAU G CAGCACUA
765
UAGTGCTG GGCTAGCTACAACGA ATCCTTGT
17184


3052
AGGAUGCA G CACUACAC
7652
GTGTAGTG GGCTAGCTACAACGA TGCATCCT
17185


3054
GAUGCAGC A CUACACAU
4779
ATGTGTAG GGCTAGCTACAACGA GCTGCATC
17186


3057
GCAGCACU A CACAUGGA
489
TCCATGTG GGCTAGCTACAACGA AGTGCTGC
17187


3059
AGCACUAC A CAUGGAGC
4781
GCTCCATG GGCTAGCTACAACGA GTAGTGCT
17188


3061
CACUACAC A UGGAGCCU
4782
AGGCTCCA GGCTAGCTACAACGA GTGTAGTG
17189


3066
CACAUGGA G CCUAAGAA
7653
TTCTTAGG GGCTAGCTACAACGA TCCATGTG
17190


3082
AAGAAAAA A UGGAGCCA
7654
TGGCTCCA GGCTAGCTACAACGA TTTTTCTT
17191


3087
AAAAUGGA G CCAGGCCU
7655
AGGCCTGG GGCTAGCTACAACGA TCCATTTT
17192


3092
GGAGCCAG G CCUGGAAC
7656
GTTCCAGG GGCTAGCTACAACGA CTGGCTCC
17193


3099
GGCCUGGA A CAAGGCAA
7657
TTGCCTTG GGCTAGCTACAACGA TCCAGGCC
17194


3104
GGAACAAG G CAAGAAAC
7658
GTTTCTTG GGCTAGCTACAACGA CTTGTTCC
17195


3111
GGCAAGAA A CCAAGACU
7659
AGTCTTGG GGCTAGCTACAACGA TTCTTGCC
17196


3117
AAACCAAG A CUAGAUAG
7660
CTATCTAG GGCTAGCTACAACGA CTTGGTTT
17197


3122
AAGACUAG A UAGCGUCA
766
UGACGCTA GGCTAGCTACAACGA CTAGTCTT
17198


3125
ACUAGAUA G CGUCACCA
7662
TGGTGACG GGCTAGCTACAACGA TATCTAGT
17199


3127
UAGAUAGC G UCACCAGC
7663
GCTGGTGA GGCTAGCTACAACGA GCTATCTA
17200


3130
AUAGCGUC A CCAGCAGC
4794
GCTGCTGG GGCTAGCTACAACGA GACGCTAT
17201


3134
CGUCACCA G CAGCGAAA
7664
TTTCGCTG GGCTAGCTACAACGA TGGTGACG
17202


3137
CACCAGCA G CGAAAGCU
7665
AGCTTTCG GGCTAGCTACAACGA TGCTGGTG
17203


3143
CAGCGAAA G CUUUGCGA
7666
TCGCAAAG GGCTAGCTACAACGA TTTCGCTG
17204


3148
AAAGCUUU G CGAGCUCC
7667
GGAGCTCG GGCTAGCTACAACGA AAAGCTTT
17205


3152
CUUUGCGA G CUCCGGCU
7668
AGCCGGAG GGCTAGCTACAACGA TCGCAAAG
17206


3158
GAGCUCCG G CUUUCAGG
7669
CCTGAAAG GGCTAGCTACAACGA CGGAGCTC
17207


3170
UCAGGAAG A UAAAAGUC
7670
GACTTTTA GGCTAGCTACAACGA CTTCCTGA
17208


3176
AGAUAAAA G UCUGAGUG
7671
CACTCAGA GGCTAGCTACAACGA TTTTATCT
17209


3182
AAGUCUGA G UGAUGUUG
7672
CAACATCA GGCTAGCTACAACGA TCAGACTT
17210


3185
UCUGAGUG A UGUUGAGG
7673
CCTCAACA GGCTAGCTACAACGA CACTCAGA
17211


3187
UGAGUGAU G UUGAGGAA
7674
TTCCTCAA GGCTAGCTACAACGA ATCACTCA
17212


3203
AGAGGAGG A UUCUGACG
7675
CGTCAGAA GGCTAGCTACAACGA CCTCCTCT
17213


3209
GGAUUCUG A CGGUUUCU
7676
AGAAACCG GGCTAGCTACAACGA CAGAATCC
17214


3212
UUCUGACG G UUUCUACA
7677
TGTAGAAA GGCTAGCTACAACGA CGTCAGAA
17215


3218
CGGUUUCU A CAAGGAGC
508
GCTCCTTG GGCTAGCTACAACGA AGAAACCG
17216


3225
UACAAGGA G CCCAUCAC
7678
GTGATGGG GGCTAGCTACAACGA TCCTTGTA
17217


3229
AGGAGCCC A UCACUAUG
4809
CATAGTGA GGCTAGCTACAACGA GGCCTCCT
17218


3232
AGCCCAUC A CUAUGGAA
4810
TTCCATAG GGCTAGCTACAACGA GATGGGCT
17219


3235
CCAUCACU A UGGAAGAU
510
ATCTTCCA GGCTAGCTACAACGA AGTGATGG
17220


3242
UAUGGAAG A UCUGAUUU
7679
AAATCAGA GGCTAGCTACAACGA CTTCCATA
17221


3247
AAGAUCUG A UUUCUUAC
7680
GTAAGAAA GGCTAGCTACAACGA CAGATCTT
17222


3254
GAUUUCUU A CAGUUUUC
516
GAAAACTG GGCTAGCTACAACGA AAGAAATC
17223


3257
UUCUUACA G UUUUCAAG
7681
CTTGAAAA GGCTAGCTACAACGA TGTAAGAA
17224


3265
GUUUUCAA G UGGCCAGA
7682
TCTGGCCA GGCTAGCTACAACGA TTGAAAAC
17225


3268
UUCAAGUG G CCAGAGGC
7683
GCCTCTGG GGCTAGCTACAACGA CACTTGAA
17226


3275
GGCCAGAG G CAUGGAGU
7684
ACTCCATG GGCTAGCTACAACGA CTCTGGCC
17227


3277
CCAGAGGC A UGGAGUUC
4818
GAACTCCA GGCTAGCTACAACGA GCCTCTGG
17228


3282
GGCAUGGA G UUCCUGUC
7685
GACAGGAA GGCTAGCTACAACGA TCCATGCC
17229


3288
GAGUUCCU G UCUUCCAG
7686
CTGGAAGA GGCTAGCTACAACGA AGGAACTC
17230


3300
UCCAGAAA G UGCAUUCA
7687
TGAATGCA GGCTAGCTACAACGA TTTCTGGA
17231


3302
CAGAAAGU C CAUUCAUC
7688
GATGAATG GGCTAGCTACAACGA ACTTTCTG
17232


3304
GAAAGUGC A UUCAUCGG
4824
CCGATGAA GGCTAGCTACAACGA GCACTTTC
17233


3308
GUGCAUUC A UCGGGACC
4825
GGTCCCGA GGCTAGCTACAACGA GAATGCAC
17234


3314
UCAUCGGG A CCUGGCAG
7689
CTGCCAGG GGCTAGCTACAACGA CCCGATGA
17235


3319
GGGACCUG C CACCGACA
7690
TCTCCCTG GGCTAGCTACAACGA CAGGTCCC
17236


3322
ACCUGGCA G CCAGAAAC
7691
GTTTCTCC CGCTACCTACAACGA TGCCACGT
17237


3329
ACCCACAA A CAUUCUUU
7692
AAAGAATG GGCTAGCTACAACGA TTCTCGCT
17238


3331
CGAGAAAC A UUCUUUUA
4829
TAAAAGAA GGCTAGCTACAACGA GTTTCTCG
17239


3339
AUUCUUUU A UCUGAGAA
534
TTCTCAGA GGCTAGCTACAACGA AAAAGAAT
17240


3347
AUCUGAGA A CAACGUCG
7693
CCACGTTG GGCTAGCTACAACGA TCTCAGAT
17241


3350
UGAGAACA A CGUGGUCA
7694
TCACCACG CGCTAGCTACAACGA TGTTCTCA
17242


3352
AGAACAAC G UGGUGAAG
7695
CTTCACCA CCCTACCTACAACGA CTTCTTCT
17243


3355
ACAACGUG G UCAAGAUU
7696
AATCTTCA GGCTAGCTACAACGA CACGTTGT
17244


3361
UCCUGAAG A UUUCUGAU
7697
ATCACAAA GGCTAGCTACAACGA CTTCACCA
17245


3365
GAAGAUUU C UGAUUUUG
7698
CAAAATCA GGCTAGCTACAACGA AAATCTTC
17246


3368
CAUUUGUG A UUUUGGCC
7699
GGCCAAAA GCCTAGCTACAACGA CACAAATC
17247


3374
UGAUUUUG G CCUUGCCC
7700
GGGCAAGG GGCTAGCTACAACGA CAAAATCA
17248


3379
UUGGCCUU G CCCGGGAU
7701
ATCCCCCG GGCTAGCTACAACGA AAGGCCAA
17249


3386
UGCCCGGC A UAUUUAUA
7702
TATAAATA GGCTAGCTACAACGA CCCGGGCA
17250


3388
CCCGGGAU A UUUAUAAG
542
CTTATAAA GGCTAGCTACAACGA ATCCCGGG
17251


3392
GCAUAUUU A UAAGAACC
545
CGTTCTTA CGCTAGCTACAACGA AAATATCC
17252


3398
UUAUAAGA A CCCCGAUU
7703
AATCGGGG GGCTAGCTACAACGA TCTTATAA
17253


3404
CAACCCCG A UUAUGUCA
7704
TCACATAA CGCTAGCTACAACGA CGGGGTTC
17254


3407
CCCCGAUU A UGUCAGAA
548
TTCTCACA GGCTACCTACAACGA AATCGGGG
17255


3409
CCGAUUAU C UCACAAAA
7705
TTTTCTCA GGCTAGCTACAACGA ATAATCCG
17256


3422
AAAAGGAG A UACUCGAC
7706
GTCGAGTA GGCTAGCTACAACGA CTCCTTTT
17257


3424
AAGCAGAU A CUCGACUU
549
AAGTCGAG GGCTAGCTACAACGA ATCTCCTT
17258


3429
GAUACUCG A CUUCCUCU
7707
AGAGGAAG GGCTAGCTACAACGA CGAGTATC
17259


3441
CCUCUGAA A UGGAUGGC
7708
GCCATCCA GGCTAGCTACAACGA TTCAGAGG
17260


3445
UGAAAUGG A UGGCUCCC
7709
CGGACCCA GGCTAGCTACAACGA CCATTTCA
17261


3448
AAUCCAUG G CUCCCGAA
7710
TTCGGGAG GGCTAGCTACAACGA CATCCATT
17262


3456
GCUCCCGA A UCUAUCUU
7711
AAGATAGA GGCTAGCTACAACGA TCGGGAGC
17263


3460
CCGAAUCU A UCUUUGAC
556
TCAAAGA GGCTAGCTACAACGA AGATTCGG
17264


3467
UAUCUUUG A CAAAAUCU
7712
AGATTTTG GGCTAGCTACAACGA CAAAGATA
17265


3472
UUGACAAA A UCUACAGC
7713
GCTGTAGA GGCTAGCTACAACGA TTTGTCAA
17266


3476
CAAAAUCU A CAGCACCA
56
UGGTGCTG GGCTAGCTACAACGA AGATTTTG
17267


3479
AAUCUACA G CACCAAGA
7714
TCTTGGTG GGCTAGCTACAACGA TGTAGATT
17268


3481
UCUACAGC A CCAAGAGC
4853
GCTCTTGG GGCTAGCTACAACGA GCTGTAGA
17269


3488
CACCAAGA G CGACGUGU
7715
ACACGTCG GGCTAGCTACAACGA TCTTGGTG
17270


3491
CAAGAGCG A CGUGUGGU
7716
ACCACACG GGCTAGCTACAACGA CGCTCTTG
17271


3493
AGAGCGAC G UGUGGUCU
7717
AGACCACA GGCTAGCTACAACGA GTCGCTCT
17272


3495
AGCGACGU C UGGUCUUA
7718
TAAGACCA GGCTAGCTACAACGA ACGTCGCT
17273


3498
GACGUGUG G UCUUACGG
7719
CCGTAAGA GGCTAGCTACAACGA CACACGTC
17274


3503
GUGGUCUG A CGGAGUAU
564
ATACTCCG GGCTAGCTACAACGA AAGACCAC
17275


3508
CUUACGGA C UAUUGCUG
7720
CAGCAATA GGCTAGCTACAACGA TCCGTAAG
17276


3510
UACGGAGU A UUGCUGUG
565
CACAGCAA GGCTAGCTACAACGA ACTCCGTA
17277


3513
GGAGUAUU G CUGUGGGA
772
UGCCACAG GGCTAGCTACAACGA AATACTCC
17278


3516
GUAUUGCU G UGGGAAAU
7722
ATTTCCCA GGCTAGCTACAACGA AGCAATAC
17279


3523
UGUGGGAA A UCUUCUCC
7723
GGAGAAGA GGCTAGCTACAACGA TTCCCACA
17280


3536
CUCCUUAG C UGGGUCUC
7724
GAGACCCA GGCTAGCTACAACGA CTAAGGAG
17281


3540
UUAGGUGG G UCUCCAUA
7725
TATGGAGA GGCTAGCTACAACGA CCACCTAA
17282


3546
GGGUCUCC A UACCCAGG
4864
CCTGGGTA GGCTAGCTACAACGA GGACACCC
17283


3548
GUCUCCAC A CCCAGGAG
575
CTCCTGGG GGCTAGCTACAACGA ATGGAGAC
17284


3556
ACCCAGGA G UACAAAUG
7726
CATTTGTA GGCTAGCTACAACGA TCCTGGGT
17285


3558
CCAGGAGU A CAAAUGGA
576
TCCATTTG GGCTAGCTACAACGA ACTCCTGG
17286


3562
GAGUACAA A UGGAUGAG
7727
CTCATCCA GGCTAGCTACAACGA TTGTACTC
17287


3566
ACAAAUGG A UGAGGACU
7728
AGTCCTCA GGCTAGCTACAACGA CCATTTGT
17288


3572
GGAUGAGG A CUUUUGCA
7729
TGCAAAAG GGCTAGCTACAACGA CCTCATCC
17289


3578
GGACUUUU C CAGUCGCC
7730
GGCGACTG GGCTAGCTACAACGA AAAAGTCC
17290


3581
CUUUUGCA G UCGCCUGA
773
UCAGGCGA GGCTAGCTACAACGA TGCAAAAG
17291


3584
UUGCAGUC G CCUGAGGG
7732
CCCTCAGG GGCTAGCTACAACGA GACTGCAA
17292


3596
GAGGGAAG G CAUGAGGA
7733
TCCTCATG GGCTAGCTACAACGA CTTCCCTC
17293


3598
GGGAAGGC A UGAGGAUG
4873
CATCCTCA GGCTAGCTACAACGA GCCTTCCC
17294


3604
GCAUGAGG A UGAGAGCU
7734
AGCTCTCA GGCTAGCTACAACGA CCTCATGC
17295


3610
GGAUGAGA G CUCCUGAG
7735
CTCAGGAG GGCTAGCTACAACGA TCTCATCC
17296


3618
GCUCCUGA G UACUCUAC
7736
GTAGAGTA GGCTAGCTACAACGA TCAGGAGC
17297


3620
UCCUGAGU A CUCUACUC
582
GAGTAGAG GGCTAGCTACAACGA ACTCAGGA
17298


3625
AGUACUCU A CUCCUGAA
584
TTCAGGAG GGCTAGCTACAACGA AGAGTACT
17299


3634
CUCCUGAA A UCUAUCAG
7737
CTGATAGA GGCTAGCTACAACGA TTCAGGAG
17300


3638
UGAAAUCU A UCAGAUCA
587
TGATCTGA GGCTAGCTACAACGA AGATTTCA
17301


3643
UCUAUCAG A UCAUGCUG
7738
CAGCATGA GGCTAGCTACAACGA CTGATAGA
17302


3646
AUCAGAUC A UCCUGGAC
4884
GTCCAGCA GGCTAGCTACAACGA GATCTGAT
17303


3648
CAGAUCAU G CUGGACUG
7739
CAGTCCAG GGCTAGCTACAACGA ATGATCTG
17304


3653
CAUGCUGG A CUGCUGGC
7740
GCCAGCAG GGCTAGCTACAACGA CCAGCATG
17305


3656
GCUGGACU G CUGGCACA
774
UGTGCCAG GGCTAGCTACAACGA AGTCCAGC
17306


3660
GACUCCUG C CACACAGA
7742
TCTCTGTG GGCTAGCTACAACGA CAGCAGTC
17307


3662
CUGCUGGC A CAGAGACC
4888
GGTCTCTG GGCTACCTACAACGA GCCAGCAG
17308


3668
GCACAGAG A CCCAAAAG
7743
CTTTTGGG GGCTAGCTACAACGA CTCTGTGC
17309


3681
AAAGAAAG G CCAAGAUU
7744
AATCTTGG GGCTAGCTACAACGA CTTTCTTT
17310


3687
AGGCCAAG A UUUGCAGA
7745
TCTGCAAA GCCTAGCTACAACGA CTTGGCCT
17311


3691
CAAGAUUU G CAGAACUU
7746
AAGTTCTG GGCTAGCTACAACGA AAATCTTG
17312


3696
UUUGCAGA A CUUGUGGA
7747
TCCACAAG GGCTAGCTACAACGA TCTGCAAA
17313


3700
CAGAACUU G UGGAAAAA
7748
TTTTTCCA GGCTAGCTACAACGA AAGTTCTG
17314


3708
GUGGAAAA A CUAGGUGA
7749
TCACCTAG GGCTAGCTACAACGA TTTTCCAC
17315


3713
AAAACUAG G UGAUUUGC
7750
GCAAATCA GGCTAGCTACAACGA CTAGTTTT
17316


3716
ACUAGGUG A UUUGCUUC
7751
GAAGCAAA GGCTAGCTACAACGA CACCTAGT
17317


3720
GGUGAUUU C CUUCAAGC
7752
GCTTGAAG GGCTAGCTACAACGA AAATCACC
17318


3727
UGCUUCAA G CAAAUGUA
7753
TACATTTG GGCTAGCTACAACGA TTGAAGCA
17319


3731
UCAAGCAA A UGUACAAC
7754
GTTGTACA GGCTAGCTACAACGA TTGCTTGA
17320


3733
AAGCAAAU C UACAACAG
7755
CTGTTGTA GGCTAGCTACAACGA ATTTGCTT
17321


3735
GCAAAUGU A CAACAGGA
598
TCCTGTTG GGCTAGCTACAACGA ACATTTGC
17322


3738
AAUGUACA A CAGGAUGG
7756
CCATCCTG GGCTAGCTACAACGA TGTACATT
17323


3743
ACAACAGG A UGGUAAAG
7757
CTTTACCA GGCTAGCTACAACGA CCTGTTGT
17324


3746
ACAGGAUG C UAAAGACU
7758
AGTCTTTA GGCTAGCTACAACGA CATCCTGT
17325


3752
UGGUAAAG A CUACAUCC
7759
GGATGTAG GGCTAGCTACAACGA CTTTACCA
17326


3755
UAAAGACU A CAUCCCAA
600
TTGGGATG GGCTAGCTACAACGA AGTCTTTA
17327


3757
AAGACUAC A UCCCAAUC
4904
GATTGGGA GGCTAGCTACAACGA GTAGTCTT
17328


3763
ACAUCCCA A UCAAUGCC
7760
GGCATTGA GGCTACCTACAACGA TGGCATCT
17329


3767
CCCAAUCA A UGCCAUAC
7761
GTATGGCA GGCTAGCTACAACGA TGATTGGG
17330


3769
CAAUCAAU G CCAUACUG
7762
CAGTATGG GGCTAGCTACAACGA ATTGATTG
17331


3772
UCAAUGCC A UACUGACA
4910
TGTCAGTA GGCTAGCTACAACGA GGCATTGA
17332


3774
AAUGCCAU A CUGACAGG
603
CCTGTCAG GGCTAGCTACAACGA ATGGCATT
17333


3778
CCAUACUG A CAGGAAAU
7763
ATTTCCTG GGCTAGCTACAACGA CAGTATGG
17334


3785
GACAGGAA A UAGUGGGU
7764
ACCCACTA GGCTAGCTACAACGA TTCCTGTC
17335


3788
AGGAAAUA G UGGGUUUA
7765
TAAACCCA CGCTAGCTACAACGA TATTTCCT
17336


3792
AAUAGUGG G UUUACAUA
7766
TATGTAAA GGCTAGCTACAACGA CCACTATT
17337


3796
GUGGGUUU A CAUACUCA
607
TGAGTATG GGCTAGCTACAACGA AAACCCAC
17338


3798
GGCUUUAC A UACUCAAC
4913
GTTGAGTA GGCTAGCTACAACGA GTAAACCC
17339


3800
GUUUACAU A CUCAACUC
608
GAGTTGAG GGCTAGCTACAACGA ATGTAAAC
17340


3805
CAUACUCA A CUCCUGCC
7767
GGCAGGAG GGCTAGCTACAACGA TGAGTATG
17341


3811
CAACUCCU G CCUUCUCU
7768
AGAGAAGG GGCTAGCTACAACGA AGGAGTTG
17342


3824
CUCUGAGG A CUUCUUCA
7769
TGAAGAAG GGCTAGCTACAACGA CCTCAGAG
17343


3839
CAAGGAAA C UAUUUCAG
7770
CTGAAATA GGCTAGCTACAACGA TTTCCTTG
17344


3841
AGGAAAGU A UUUCAGCU
618
AGCTGAAA GGCTAGCTACAACGA ACTTTCCT
17345


3847
GUAUUUCA C CUCCGAAG
7771
CTTCGGAG GGCTAGCTACAACGA TGAAATAC
17346


3855
GCUCCGAA G UUUAAUUC
7772
GAATTAAA GGCTAGCTACAACGA TTCGGAGC
17347


3860
GAAGUUUA A UUCAGGAA
7773
TTCCTGAA GGCTAGCTACAACGA TAAACTTC
17348


3869
UUCAGGAA C CUCUGAUG
7774
CATCAGAG GGCTAGCTACAACGA TTCCTGAA
17349


3875
AAGCUCUG A UGAUGUCA
7775
TCACATCA GCCTAGCTACAACGA CACACCTT
17350


3878
CUCUGAUG A UGUCAGAU
7776
ATCTGACA GGCTAGCTACAACGA CATCAGAG
17351


3880
CUGAUGAU C UCAGAUAU
7777
ATATCTGA GCCTAGCTACAACGA ATCATCAG
17352


3885
GAUGUCAC A UAUGUAAA
7778
TTTACATA GGCTAGCTACAACGA CTGACATC
17353


3887
UGUCAGAU A UCUAAAUG
630
CATTTACA GGCTAGCTACAACGA ATCTCACA
17354


3889
UCAGAUAU C UAAAUGCU
7779
ACCATTTA GGCTAGCTACAACGA ATATCTGA
17355


3893
AUAUGUAA A UCCUCUCA
7780
TGAAAGCA GGCTAGCTACAACGA TTACATAT
17356


3895
AUGUAAAU C CUUUCAAG
7781
CTTGAAAG GGCTAGCTACAACGA ATTTACAT
17357


3903
GCUUUCAA C UUCAUGAG
7782
CTCATGAA GGCTAGCTACAACGA TTGAAAGC
17358


3907
UCAAGUUC A UGAGCCUC
4935
CACGCTCA GCCTAGCTACAACGA CAACTTCA
17359


3911
GUUCAUGA C CCUGGAAA
7783
TTTCCAGG GGCTAGCTACAACGA TCATGAAC
17360


3922
UGGAAAGA A UCAAAACC
7784
GGTTTTGA GGCTAGCTACAACGA TCTTTCCA
17361


3928
GAAUCAAA A CCUUUGAA
7785
TTCAAAGG GGCTAGCTACAACGA TTTGATTC
17362


3939
UUUGAAGA A CUUUUACC
7786
GGTAAAAG GGCTAGCTACAACGA TCTTCAAA
17363


3945
GAACUUUU A CCGAAUGC
643
GCATTCGG GGCTAGCTACAACGA AAAAGTTC
17364


3950
UUUACCGA A UGCCACCU
7787
AGGTGGCA GGCTAGCTACAACGA TCGGTAAA
17365


3952
UACCGAAV C CCACCUCC
7788
GGAGGTGG GGCTAGCTACAACGA ATTCGGTA
17366


3955
CGAAUGCC A CCUCCAUG
4944
CATGGAGG GGCTAGCTACAACGA GGCATTCG
17367


3961
CCACCUCC A UGUUUGAU
4948
ATCAAACA GGCTAGCTACAACGA GGAGGTGG
17368


3963
ACCUCCAU G UUUGAUGA
7789
TCATCAAA GGCTAGCTACAACGA ATGCAGGT
17369


3968
CAUGUUUG A UGACUACC
7790
GGTAGTCA GGCTAGCTACAACGA CAAACATG
17370


3971
GUUUGAUG A CUACCAGG
7791
CCTGGTAG GGCTAGCTACAACGA CATCAAAC
17371


3974
UGAUGACU A CCAGCGCC
647
CGCCCTGG CGCTAGCTACAACGA AGTCATCA
17372


3980
CUACCAGG C CGACAGCA
7792
TGCTGTCG GGCTAGCTACAACGA CCTGCTAG
17373


3983
CCAGGCCG A CAGCAGCA
7793
TGCTGCTG GGCTAGCTACAACGA CGCCCTGG
17374


3986
GGGCGACA G CAGCACUC
7794
GAGTGCTG GGCTAGCTACAACGA TGTCGCCC
17375


3989
CGACAGCA C CACUCUCU
7795
ACAGAGTG CGCTAGCTACAACGA TGCTGTCG
17376


3991
ACAGCACC A CUCUGUUG
4954
CAACAGAG GGCTAGCTACAACGA CCTGCTGT
17377


3996
ACCACUCU C UUGGCCUC
7796
GAGGCCAA GGCTAGCTACAACGA AGACTCCT
17378


4000
CUCUCUUG C CCUCUCCC
7797
CGCACACC GGCTACCTACAACGA CAACAGAC
17379


4009
CCUCUCCC A UGCUGAAG
4962
CTTCAGCA CGCTAGCTACAACGA GGGAGAGG
17380


4011
UCUCCCAU G CUGAAGCG
7798
CGCTTCAG GGCTACCTACAACGA ATGCCACA
17381


4017
AUGCUCAA G CGCUUCAC
7799
CTGAAGCG GGCTAGCTACAACGA TTCAGCAT
17382


4019
CCUCAACC G CUUCACCU
7800
ACGTCAAG CGCTAGCTACAACGA GCTTCAGC
17383


4024
ACCGCUUC A CCUGCACU
4965
ACTCCAGC GGCTAGCTACAACGA GAAGCGCT
17384


4030
UCACCUGC A CUGACAGC
7801
CCTCTCAC CCCTACCTACAACGA CCAGCTCA
17385


4034
CUGGACUG A CAGCAAAC
7802
GTTTGCTG GGCTACCTACAACGA CAGTCCAG
17386


4037
GACUGACA C CAAACCCA
7803
TGGGTTTC GGCTACCTACAACGA TCTCAGTC
17387


4041
GACAGCAA A CCCAAGGC
7804
GCCTTCCC GCCTAGCTACAACGA TTGCTGTC
17388


4048
AACCCAAC G CCUCGCUC
7805
CACCCACG GGCTAGCTACAACGA CTTCGCTT
17389


4053
AAGGCCUC C CUCAAGAU
7806
ATCTTCAG GGCTACCTACAACGA GAGGCCTT
17390


4060
CGCUCAAG A UUGACUUG
7807
CAACTCAA GGCTACCTACAACGA CTTCAGCC
17391


4064
CAACAUUG A CUCCACAG
7808
CTCTCAAC GGCTAGCTACAACGA CAATCTTG
17392


4072
ACUUCAGA C UAACCACU
7809
ACTCCTTA GGCTACCTACAACGA TCTCAAGT
17393


4075
UCACACCA A CCAGUAAA
7810
TTTACTGG GCCTAGCTACAACGA TACTCTCA
17394


4079
AGUAACCA C UAAAAGUA
781
UACTTTTA GCCTAGCTACAACGA TGGTTACT
17395


4085
CAGUAAAA C UAAGCACU
7812
ACTCCTTA GGCTAGCTACAACGA TTTTACTC
17396


4092
ACUAACCA C UCCGCCCU
7813
ACCCCCGA GGCTACCTACAACGA TCCTTACT
17397


4098
CACUCCGC C CUCUCUGA
7814
TCACACAC CGCTAGCTACAACGA CCCCACTC
17398


4101
UCCCCGCU C UCUCAUGU
7815
ACATCAGA GGCTAGCTACAACGA AGCCCCGA
17399


4106
GCUCUCUC A UCUCAGCA
7816
TGCTCACA GGCTAGCTACAACGA CAGACACC
17400


4108
UCUCUCAU C UCACCACC
7817
CCTGCTCA GGCTAGCTACAACGA ATCAGACA
17401


4112
UCAUCUCA C CACCCCCA
7818
TCCGCCTC CCCTAGCTACAACGA TCACATCA
17402


4116
CUCACCAG C CCCAGUUU
7819
AAACTCGC GGCTAGCTACAACGA CTCCTGAC
17403


4121
CACCCCCA C UUUCUCCC
7820
GGCAGAAA GGCTAGCTACAACGA TCCCCCTC
17404


4127
CACUUUCU C CCAUUCCA
782
UCGAATCG GGCTAGCTACAACGA ACAAACTG
17405


4130
UUUCUCCC A UUCCACCU
4990
AGCTCGAA CGCTAGCTACAACGA CGCACAAA
17406


4136
CCAUUCCA C CUGUGGGC
7822
CCCCACAC CGCTAGCTACAACGA TGCAATGG
17407


4139
UUCCACCU C UGCCCACC
7823
CGTCCCCA CCCTACCTACAACGA ACCTGCAA
17408


4143
AGCUGUGG C CACCUCAG
7824
CTCACGTG GGCTAGCTACAACGA CCACACCT
17409


4145
CUGUGGGC A CGUCAGCG
4994
CGCTGACG GGCTAGCTACAACGA CCCCACAG
17410


4147
GUGGGCAC G UCAGCGAA
7825
TTCGCTGA GGCTAGCTACAACGA GTGCCCAC
17411


4151
GCACGUCA G CGAAGGCA
7828
TGCCTTCG GGCTAGCTACAACGA TGACGTGC
17412


4157
CAGCGAAG G CAAGCGCA
7827
TGCGCTTG GGCTAGCTACAACGA CTTCGCTG
17413


4161
GAAGGCAA G CGCAGGUU
7828
AACCTGCG GGCTAGCTACAACGA TTGCCTTC
17414


4163
AGGCAAGC G CAGGUUCA
7829
TGAACCTG GGCTAGCTACAACGA GCTTGCCT
17415


4167
AAGCGCAG G UUCACCUA
7830
TAGGTGAA GGCTAGCTACAACGA CTGCGCTT
17416


4171
GCAGGUUC A CCUACGAC
4998
GTCGTAGG GGCTAGCTACAACGA GAACCTGC
17417


4175
GUUCACCU A CGACCACG
672
CGTGGTCG GGCTAGCTACAACGA AGGTGAAC
17418


4178
CACCUACG A CCACGCUG
7831
CAGCGTGG GGCTAGCTACAACGA CGTAGGTG
17419


4181
CUACGACC A CGCUGAGC
5002
GCTCAGCG GGCTAGCTACAACGA GGTCGTAG
17420


4183
ACGACCAC G CUGASCUG
7832
CAGCTCAG GGCTAGCTACAACGA GTGGTCGT
17421


4188
CACGCUGA G CUGGAAAG
7833
CTTTCCAG GGCTAGCTACAACGA TCASCGTG
17422


4201
AAAGGAAA A UCGCGUGC
7834
GCACGCGA GGCTAGCTACAACGA TTTCCTTT
17423


4204
GGAAAAUC G CGUGCUGC
7835
GCASCACG GGCTAGCTACAACGA GATTTTCC
17424


4206
AAAAUCSC G UGCUGCUC
7836
GAGCAGCA GGCTAGCTACAACGA GCGATTTT
17425


4208
AAUCGCGU G CUGCUCCC
7837
GGGAGCAG GGCTAGCTACAACSA ACGCGATT
17426


4211
CGCGUGCU G CUCCCCGC
7838
GCGGGGAG GGCTAGCTACAACGA AGCACGCG
17427


4218
UGCUCCCC G CCCCCAGA
7839
TCTGGGGG GGCTAGCTACAACSA SGGGAGCA
17428


4226
GCCCCCAG A CUACAACU
7840
AGTTGTAG SGCTAGCTACAACGA CTGGGGGC
17429


4229
CCCAGACU A CAACUCGG
675
CCGAGTTG GGCTAGCTACAACGA AGTCTGSG
17430


4232
AGACUACA A CUCGGUGG
7841
CCACCGAG GGCTAGCTACAACSA TGTAGTCT
17431


4237
ACAACUCG G UGGUCCUG
7842
CAGGACCA GGCTAGCTACAACGA CGAGTTGT
17432


4240
ACUCGGUG G UCCUGUAC
7843
GTACAGGA GGCTAGCTACAACGA CACCGAST
17433


4245
GUGGUCCU G UACUCCAC
7844
GTGGAGTA GGCTAGCTACAACSA AGGACCAC
17434


4247
GGUCCUGU A CUCCACCC
678
GGGTGGAG GGCTAGCTACAACGA ACAGGACC
17435


4252
UGUACUCC A CCCCACCC
5022
GGGTGGGG GGCTAGCTACAACGA GGAGTACA
17436


4257
UCCACCCC A CCCAUCUA
5026
TAGATGGG GGCTAGCTACAACGA GGGGTGGA
17437


4261
CCCCACCC A UCUAGAGU
5029
ACTCTAGA GGCTAGCTACAACGA SSSTGGGG
17438


4268
CAUCUAGA G UUUGACAC
7845
GTGTCAAA GGCTAGCTACAACGA TCTAGATG
17439


4273
AGAGUUUS A CACGAAGC
7846
GCTTCGTG GGCTAGCTACAACGA CAAACTCT
17440


4275
AGUUUGAC A CGAAGCCU
5031
AGGCTTCG GGCTAGCTACAACGA GTCAAACT
17441


4280
GACACGAA G CCUUAUUU
7847
AAATAAGG GGCTAGCTACAACGA TTCGTSTC
17442


4285
GAAGCCUU A UUUCUAGA
685
TCTAGAAA GGCTAGCTACAACGA AAGGCTTC
17443


4295
UUCUAGAA G CACAUGUG
7848
CACATGTG GGCTAGCTACAACGA TTCTAGAA
17444


4297
CUAGAAGC A CAUGUGUA
5035
TACACATG GGCTAGCTACAACGA GCTTCTAG
17445


4299
AGAAGCAC A USUSUAUU
5036
AATACACA GGCTAGCTACAACGA STGCTTCT
17446


4301
AAGCACAU G USUAUUUA
7849
TAAATACA GGCTAGCTACAACGA ATSTGCTT
17447


4303
GCACAUGU G UAUUUAUA
7850
TATAAATA GGCTAGCTACAACGA ACATSTGC
17448


4305
ACAUGUGU A UUUAUACC
690
GGTATAAA GGCTAGCTACAACGA ACACATGT
17449


4309
GUGUAUUU A UACCCCCA
693
TSGGGGTA GGCTAGCTACAACGA AAATACAC
17450


4311
GUAUUUAU A CCCCCAGG
694
CCTGGGGG GGCTAGCTACAACGA ATAAATAC
17451


4322
CCCAGGAA A CUAGCUUU
7851
AAAGCTAG GGCTAGCTACAACGA TTCCTGGG
17452


4326
GGAAACUA G CUUUUGCC
7852
GGCAAAAG GGCTAGCTACAACGA TAGTTTCC
17453


4332
UAGCUUUU G CCAGUAUU
7853
AATACTGG GGCTAGCTACAACGA AAAAGCTA
17454


4336
UUUUGCCA G UAUUAUGC
7854
GCATAATA GGCTAGCTACAACGA TGGCAAAA
17455


4338
UUGCCAGU A UUAUGCAU
699
ATGCATAA GGCTAGCTACAACGA ACTGGCAA
17456


4341
CCAGUAUU A UGCAUAUA
70
UATATGCA GGCTAGCTAGAACGA AATACTGG
17457


4343
AGUAUUAU G CAUAUAUA
7855
TATATATG GGCTAGCTACAACGA ATAATACT
17458


4345
UAUUAUGC A UAUAUAAG
5046
CTTATATA GGCTAGCTACAACGA GCATAATA
17459


4347
UUAUGCAU A UAUAAGUU
702
AACTTATA GGCTAGCTACAACGA ATGCATAA
17460


4349
AUGCAUAU A UAAGUUUA
703
TAAACTTA GGCTAGCTACAACGA ATATGCAT
17461


4353
AUAUAUAA G UUUACACC
7856
GGTGTAAA GGCTAGCTACAACGA TTATATAT
17462


4357
AUAAGUUU A CACCUUUA
707
TAAAGGTG GGCTAGCTACAACGA AAACTTAT
17463


4359
AAGUUUAC A CCUUUAUC
5047
GATAAAGG GGCTAGCTACAACGA GTAAACTT
17464


4365
ACACCUUU A UCUUUCCA
710
TGGAAAGA GGCTAGCTACAACGA AAAGGTGT
17465


4373
AUCUUUCC A UGGGAGCC
5052
GGCTCCCA GGCTAGCTACAACGA GGAAAGAT
17466


4379
CCAUGGGA G CCAGCUGC
7857
GCAGCTGG GGCTAGCTACAACGA TCCCATGG
17467


4383
GGGAGCCA G CUGCUUUU
7858
AAAAGCAG GGCTAGCTACAACGA TGGCTCCC
17468


4386
AGCCAGCU G CUUUUUGU
7859
ACAAAAAG GGCTAGCTACAACGA AGCTGGCT
17469


4393
UGCUUUUU G UGAUUUUU
7860
AAAAATCA GGCTAGCTACAACGA AAAAAGCA
17470


4396
UUUUUGUG A UUUUUUUA
786
UAAAAAAA GGCTAGCTACAACGA CACAAAAA
17471


4405
UUUUUUUA A UAGUGCUU
7862
AAGCACTA GGCTAGCTACAACGA TAAAAAAA
17472


4408
UUUUAAUA G UGCUUUUU
7863
AAAAAGCA GGCTAGCTACAACGA TATTAAAA
17473


4410
UUAAUAGU G CUUUUUUU
7864
AAAAAAAG GGCTAGCTACAACGA ACTATTAA
17474


4424
UUUUUUUG A CUAACAAG
7865
CTTGTTAG GGCTAGCTACAACGA CAAAAAAA
17475


4428
UUUGACUA A CAAGAAUG
7866
CATTCTTG GGCTAGCTACAACGA TAGTCAAA
17476


4434
UAACAAGA A UGUAACUC
7867
GAGTTACA GGCTAGCTACAACGA TCTTGTTA
17477


4436
ACAAGAAU G UAACUCCA
7868
TGGAGTTA GGCTAGCTACAACGA ATTCTTGT
17478


4439
AGAAUGUA A CUCCAGAU
7869
ATCTGGAG GGCTAGCTACAACGA TACATTCT
17479


4446
AACUCCAG A UAGAGAAA
7870
TTTCTCTA GGCTAGCTACAACGA CTGGAGTT
17480


4454
AUAGAGAA A UAGUGACA
787
UGTCACTA GGCTAGCTACAACGA TTCTCTAT
17481


4457
GAGAAAUA G UGACAAGU
7872
ACTTGTCA GGCTAGCTACAACGA TATTTCTC
17482


4460
AAAUAGUG A CAAGUGAA
7873
TTCACTTG GGCTAGCTACAACGA CACTATTT
17483


4464
AGUGACAA G UGAAGAAC
7874
GTTCTTCA GGCTAGCTACAACGA TTGTCACT
17484


4471
AGUGAAGA A CACUACUG
7875
CAGTAGTG GGCTAGCTACAACGA TCTTCACT
17485


4473
UGAAGAAC A CUACUGCU
5064
AGCAGTAG GGCTAGCTACAACGA GTTCTTCA
17486


4476
AGAACACU A CUGCUAAA
742
TTTAGCAG GGCTAGCTACAACGA AGTGTTCT
17487


4479
ACACUACU G CUAAAUCC
7876
GGATTTAG GGCTAGCTACAACGA AGTAGTGT
17488


4484
ACUGCUAA A UCCUCAUG
7877
CATGAGGA GGCTAGCTACAACGA TTAGCAGT
17489


4490
AAAUCCUC A UGUUACUC
5070
GAGTAACA GGCTAGCTACAACGA GAGGATTT
17490


4492
AUCCUCAU G UUACUCAG
7878
CTGAGTAA GGCTAGCTACAACGA ATGAGGAT
17491


4495
CUCAUGUU A CUCAGUGU
747
ACACTGAG GGCTAGCTACAACGA AACATGAG
17492


4500
GUUACUCA G UGUUAGAG
7879
CTCTAACA GGCTAGCTACAACGA TGAGTAAC
17493


4502
UACUCAGU G UUAGAGAA
7880
TTCTCTAA GGCTAGCTACAACGA ACTGAGTA
17494


4511
UUAGAGAA A UCCUUCCU
7881
AGGAAGGA GGCTAGCTACAACGA TTCTCTAA
17495


4522
CUUCCUAA A CCCAAUGA
7882
TCATTGGG GGCTAGCTACAACGA TTAGGAAG
17496


4527
UAAACCCA A UGACUUCC
7883
GGAAGTCA GGCTAGCTACAACGA TGGGTTTA
17497


4530
ACCCAAUG A CUUCCCUG
7884
CAGGGAAG GGCTAGCTACAACGA CATTGGGT
17498


4538
ACUUCCCU G CUCCAACC
7885
GGTTGGAG GGCTAGCTACAACGA AGGGAAGT
17499


4544
CUGCUCCA A CCCCCGCC
7886
GGCGGGGG GGCTAGCTACAACGA TGGAGCAG
17500


4550
CAACCCCC G CCACCUCA
7887
TGAGGTGG GGCTAGCTACAACGA GGGGGTTG
17501


4553
CCCCCGCC A CCUCAGGG
5092
CCCTGAGG GGCTAGCTACAACGA GGCGGGGG
17502


4561
ACCUCAGG G CACGCAGG
7888
CCTGCGTG GGCTAGCTACAACGA CCTGAGGT
17503


4563
CUCAGGGC A CGCAGGAC
5096
GTCCTGCG GGCTAGCTACAACGA GCCCTGAG
17504


4565
CAGGGCAC G CAGGACCA
7889
TGGTCCTG GGCTAGCTACAACGA GTGCCCTG
17505


4570
CACGCAGG A CCAGUUUG
7890
CAAACTGG GGCTAGCTACAACGA CCTGCGTG
17506


4574
CAGGACCA G UUUGAUUG
7891
CAATCAAA GGCTAGCTACAACGA TGGTCCTG
17507


4579
CCAGUUUG A UUGAGGAG
7892
CTCCTCAA GGCTAGCTACAACGA CAAACTGG
17508


4587
AUUGAGGA G CUGCACUG
7893
CAGTGCAG GGCTAGCTACAACGA TCCTCAAT
17509


4590
GAGGAGCU G CACUGAUC
7894
GATCAGTG GGCTAGCTACAACGA AGCTCCTC
17510


4592
GGAGCUGC A CUGAUCAC
5101
GTGATCAG GGCTAGCTACAACGA GCAGCTCC
17511


4596
CUGCACUG A UCACCCAA
7895
TTGGGTGA GGCTAGCTACAACGA CAGTGCAG
17512


4599
CACUGAUC A CCCAAUGC
5103
GCATTGGG GGCTAGCTACAACGA GATCAGTG
17513


4604
AUCACCCA A UGCAUCAC
7896
GTGATGCA GGCTAGCTACAACGA TGGGTGAT
17514


4606
CACCCAAU G CAUCACGU
7897
ACGTGATG GGCTAGCTACAACGA ATTGGGTG
17515


4608
CCCAAUGC A UCACGUAC
5107
GTACGTGA GGCTAGCTACAACGA GCATTGGG
17516


4611
AAUGCAUC A CGUACCCC
5108
GGGGTACG GGCTAGCTACAACGA GATGCATT
17517


4613
UGCAUCAC G UACCCCAC
7898
GTGGGGTA GGCTAGCTACAACGA GTGATGCA
17518


4615
CAUCACGU A CCCCACUG
764
CAGTGGGG GGCTAGCTACAACGA ACGTGATG
17519


4620
CGUACCCC A CUGGGCCA
5112
TGGCCCAG GGCTAGCTACAACGA GGGGTACG
17520


4625
CCCACUGG G CCAGCCCU
7899
AGGGCTGG GGCTAGCTACAACGA CCAGTGGG
17521


4629
CUGGGCCA G CCCUGCAG
7900
CTGCAGGG GGCTAGCTACAACGA TGGCCCAG
17522


4634
CCAGCCCU G CAGCCCAA
7901
UTGGGCTG GGCTAGCTACAACGA AGGGCTGG
17523


4637
GCCCUGCA G CCCAAAAC
7902
GTTTTGGG GGCTAGCTACAACGA TGCAGGGC
17524


4644
AGCCCAAA A CCCAGGGC
7903
GCCCTGGG GGCTAGCTACAACGA TTTGGGCT
17525


4651
AACCCAGG G CAACAAGC
7904
GCTTGTTG GGCTAGCTACAACGA CCTGGGTT
17526


4654
CCAGGGCA A CAAGCCCG
7905
CGGGCTTG GGCTAGCTACAACGA TGCCCTGG
17527


4658
GGCAACAA G CCCGUUAG
7906
CTAACGGG GGCTAGCTACAACGA TTGTTGCC
17528


4662
ACAAGCCC G UUAGCCCC
7907
GGGGCTAA GGCTAGCTACAACGA GGGCTTGT
17529


4666
GCCCGUUA G CCCCAGGG
7908
CCCTGGGG GGCTAGCTACAACGA TAACGGGC
17530


4676
CCCAGGGG A UCACUGGC
7909
GCCAGTGA GGCTAGCTACAACGA CCCCTGGG
17531


4679
AGGGGAUC A CUGGCUGG
5134
CCAGCCAG GGCTAGCTACAACGA GATCCCCT
17532


4683
GAUCACUG G CUGGCCUG
7910
CAGGCCAG GGCTAGCTACAACGA CAGTGATC
17533


4687
ACUGGCUG G CCUGAGCA
791
UGCTCAGG GGCTAGCTACAACGA CAGCCAGT
17534


4693
UGGCCUGA G CAACAUCU
7912
AGATGTTG GGCTAGCTACAACGA TCAGGCCA
17535


4696
CCUGAGCA A CAUCUCGG
7913
CCGAGATG GGCTAGCTACAACGA TGCTCAGG
17536


4698
UGAGCAAC A UCUCGGGA
5140
TCCCGAGA GGCTAGCTACAACGA GTTGCTCA
17537


4707
UCUCGGGA G UCCUCUAG
7914
CTAGAGGA GGCTAGCTACAACGA TCCCGAGA
17538


4715
GUCCUCUA G CAGGCCUA
7915
TAGGCCTG GGCTAGCTACAACGA TAGAGGAC
17539


4719
UCUAGCAG G CCUAAGAC
7916
GTCTTAGG GGCTAGCTACAACGA CTGCTAGA
17540


4726
GGCCUAAG A CAUGUGAG
7917
CTCACATG GGCTAGCTACAACGA CTTAGGCC
17541


4728
CCUAAGAC A UGUGAGGA
5148
TCCTCACA GGCTAGCTACAACGA GTCTTAGG
17542


4730
UAAGACAU G UGAGGAGG
7918
CCTCCTCA GGCTAGCTACAACGA ATGTCTTA
17543


4752
GAAAAAAA G CAAAAAGC
7919
GCTTTTTG GGCTAGCTACAACGA TTTTTTTC
17544


4759
AGCAAAAA G CAAGGGAG
7920
CTCCCTTG GGCTAGCTACAACGA TTTTTGCT
17545


4777
AAAGAGAA A CCGGGAGA
792
UCTCCCGG GGCTAGCTACAACGA TTCTCTTT
17546


4788
GGGAGAAG G CAUGAGAA
7922
TTCTCATG GGCTAGCTACAACGA CTTCTCCC
17547


4790
GAGAAGGC A UGAGAAAG
5152
CTTTCTCA GGCTAGCTACAACGA GCCTTCTC
17548


4800
GAGAAAGA A UUUGAGAC
7923
GTCTCAAA GGCTAGCTACAACGA TCTTTCTC
17549


4807
AAUUUGAG A CGCACCAU
7924
ATGGTGCG GGCTAGCTACAACGA CTCAAATT
17550


4809
UUUGAGAC G CACCAUGU
7925
ACATGGTG GGCTAGCTACAACGA GTCTCAAA
17551


4811
UGAGACGC A CCAUGUGG
5153
CCACATGG GGCTAGCTACAACGA GCGTCTCA
17552


4814
GACGCACC A UGUGGGCA
5155
TGCCCACA GGCTAGCTACAACGA GGTGCGTC
17553


4816
CGCACCAU G UGGGCACG
7926
CGTGCCCA GGCTAGCTACAACGA ATGGTGCG
17554


4820
CCAUGUGG G CACGGAGG
7927
CCTCCGTG GGCTAGCTACAACGA CCACATGG
17555


4822
AUGUGGGC A CGGAGGGG
5156
CCCCTCCG GGCTAGCTACAACGA GCCCACAT
17556


4832
GGAGGGGG A CGGGGCUC
7928
GAGCCCCG GGCTAGCTACAACGA CCCCCTCC
17557


4837
GGGACGGG G CUCAGCAA
7929
TTGCTGAG GGCTAGCTACAACGA CCCGTCCC
17558


4842
GGGGCUCA G CAAUGCCA
7930
TGGCATTG GGCTAGCTACAACGA TGAGCCCC
17559


4845
GCUCAGCA A UGCCAUUU
7931
AAATGGCA GGCTAGCTACAACGA TGCTGAGC
17560


4847
UCAGCAAU G CCAUUUCA
7932
TGAAATGG GGCTAGCTACAACGA ATTGCTGA
17561


4850
GCAAUGCC A UUUCAGUG
5161
CACTGAAA GGCTAGCTACAACGA GGCATTGC
17562


4856
CCAUUUCA G UGGCUUCC
7933
GGAAGCCA GGCTAGCTACAACGA TGAAATGG
17563


4859
UUUCAGUG G CUUCCCAG
7934
CTGGGAAG GGCTAGCTACAACGA CACTGAAA
17564


4867
GCUUCCCA G CUCUGACC
7935
GGTCAGAG GGCTAGCTACAACGA TGGGAAGC
17565


4873
CAGCUCUG A CCCUUCUA
7936
TAGAAGGG GGCTAGCTACAACGA CAGAGCTG
17566


4881
ACCCUUCU A CAUUUGAG
785
CTCAAATG GGCTAGCTACAACGA AGAAGGGT
17567


4883
CCUUCUAC A UUUGAGGG
5173
CCCTCAAA GGCTAGCTACAACGA GTAGAAGG
17568


4891
AUUUGAGG G CCCAGCCA
7937
TGGCTGGG GGCTAGCTACAACGA CCTCAAAT
17569


4896
AGGGCCCA G CCAGGAGC
7938
GCTCCTGG GGCTAGCTACAACGA TGGGCCCT
17570


4903
AGCCAGGA G CAGAUGGA
7939
TCCATCTG GGCTAGCTACAACGA TCCTGGCT
17571


4907
AGGAGCAG A UGGACAGG
7940
GCTGTCCA GGCTAGCTACAACGA CTGCTCCT
17572


4911
GCAGAUGG A CAGCGAUG
7941
CATCGCTG GGCTAGCTACAACGA CCATCTGC
17573


4914
GAUGGACA G CGAUGAGG
7942
CCTCATCG GGCTAGCTACAACGA TGTCCATC
17574


4917
GGACAGCG A UGAGGGGA
7943
TCCCCTCA GGCTAGCTACAACGA CGCTGTCC
17575


4925
AUGAGGGG A CAUUUUCU
7944
AGAAAATG GGCTAGCTACAACGA CCCCTCAT
17576


4927
GAGGGGAC A UUUUCUGG
5181
CCAGAAAA GGCTAGCTACAACGA GTCCCCTC
17577


4936
UUUUCUGG A UUCUGGGA
7945
TCCCAGAA GGCTAGCTACAACGA CCAGAAAA
17578


4946
UCUGGGAG G CAAGAAAA
7946
TTTTCTTG GGCTAGCTACAACGA CTCCCAGA
17579


4957
AGAAAAGG A CAAAUAUC
7947
GATATTTG GGCTAGCTACAACGA CCTTTTCT
17580


4961
AAGGACAA A UAUCUUUU
7948
AAAAGATA GGCTAGCTACAACGA TTGTCCTT
17581


4963
GGACAAAU A UCUUUUUU
794
AAAAAAGA GGCTAGCTACAACGA ATTTGTCC
17582


4975
UUUUUGGA A CUAAAGCA
7949
TGCTTTAG GGCTAGCTACAACGA TCCAAAAA
17583


4981
GAACUAAA G CAAAUUUU
7950
AAAATTTG GGCTAGCTACAACGA TTTAGTTC
17584


4985
UAAAGCAA A UUUUAGAC
7951
GTCTAAAA GGCTAGCTACAACGA TTGCTTTA
17585


4992
AAUUUUAG A CCUUUACC
7952
GGTAAAGG GGCTAGCTACAACGA CTAAAATT
17586


4998
AGACCUUU A CCUAUGGA
808
TCCATAGG GGCTAGCTACAACGA AAAGGTCT
17587


5002
CUUUACCU A UGGAAGUG
809
CACTTCCA GGCTAGCTACAACGA AGGTAAAG
17588


5008
CUAUGGAA G UGGUUCUA
7953
TAGAACCA GGCTAGCTACAACGA TTCCATAG
17589


5011
UGGAAGUG G UUCUAUGU
7954
ACATAGAA GGCTAGCTACAACGA CACTTCCA
17590


5016
GUGGUUCU A UGUCCAUU
812
AATGGACA GGCTAGCTACAACGA AGAACCAC
17591


5018
GGUUCUAU G UCCAUUCU
7955
AGAATGGA GGCTAGCTACAACGA ATAGAACC
17592


5022
CUAUGUCC A UUCUCAUU
5195
AATGAGAA GGCTAGCTACAACGA GGACATAG
17593


5028
CCAUUCUC A UUCGUGGC
5197
GCCACGAA GGCTAGCTACAACGA GAGAATGG
17594


5032
UCUCAUUC G UGGCAUGU
7956
ACATGCCA GGCTAGCTACAACGA GAATGAGA
17595


5035
CAUUCGUG G CAUGUUUU
7957
AAAACATG GGCTAGCTACAACGA CACGAATG
17596


5037
UUCGUGGC A UGUUUUGA
5198
TCAAAACA GGCTAGCTACAACGA GCCACGAA
17597


5039
CGUGGCAU G UUUUGAUU
7958
AATCAAAA GGCTAGCTACAACGA ATGCCACG
17598


5045
AUGUUUUG A UUUGUAGC
7959
GCTACAAA GGCTAGCTACAACGA CAAAACAT
17599


5049
UUUGAUUU G UAGCACUG
7960
CAGTGCTA GGCTAGCTACAACGA AAATCAAA
17600


5052
GAUUUGUA G CACUGAGG
7961
CCTCAGTG GGCTAGCTACAACGA TACAAATC
17601


5054
UUUGUAGC A CUGAGGGU
5199
ACCCTCAG GGCTAGCTACAACGA GCTACAAA
17602


5061
CACUGAGG G UGGCACUC
7962
GAGTGCCA GGCTAGCTACAACGA CCTCAGTG
17603


5064
UGAGGGUG G CACUCAAC
7963
GTTGAGTG GGCTAGCTACAACGA CACCCTCA
17604


5066
AGGGUGGC A CUCAACUC
5201
GAGTTGAG GGCTAGCTACAACGA GCCACCCT
17605


5071
GGCACUCA A CUCUGAGC
7964
GCTCAGAG GGCTAGCTACAACGA TGAGTGCC
17606


5078
AACUCUGA G CCCAUACU
7965
AGTATGGG GGCTAGCTACAACGA TCAGAGTT
17607


5082
CUGAGCCC A UACUUUUG
5208
CAAAAGTA GGCTAGCTACAACGA GGGCTCAG
17608


5084
GAGCCCAU A CUUUUGGC
827
GCCAAAAG GGCTAGCTACAACGA ATGGGCTC
17609


5091
UACUUUUG G CUCCUCUA
7966
TAGAGGAG GGCTAGCTACAACGA CAAAAGTA
17610


5100
CUCCUCUA G UAAGAUGC
7967
GCATCTTA GGCTAGCTACAACGA TAGAGGAG
17611


5105
CUAGUAAG A UGCACUGA
7968
TCAGTGCA GGCTAGCTACAACGA CTTACTAG
17612


5107
AGUAAGAU G CACUGAAA
7969
TTTCAGTG GGCTAGCTACAACGA ATCTTACT
17613


5109
UAAGAUGC A CUGAAAAC
5214
GTTTTCAG GGCTAGCTACAACGA GCATCTTA
17614


5116
CACUGAAA A CUUAGCCA
7970
TGGCTAAG GGCTAGCTACAACGA TTTCAGTG
17615


5121
AAAACUUA G CCAGAGUU
7971
AACTCTGG GGCTAGCTACAACGA TAAGTTTT
17616


5127
UAGCCAGA G UUAGGUUG
7972
CAACCTAA GGCTAGCTACAACGA TCTGGCTA
17617


5132
AGAGUUAG G UUGUCUCC
7973
GGAGACAA GGCTAGCTACAACGA CTAACTCT
17618


5135
GUUAGGUU G UCUCCAGG
7974
CCTGGAGA GGCTAGCTACAACGA AACCTAAC
17619


5143
GUCUCCAG G CCAUGAUG
7975
CATCATGG GGCTAGCTACAACGA CTGGAGAC
17620


5146
UCCAGGCC A UGAUGGCC
5223
GGCCATCA GGCTAGCTACAACGA GGCCTGGA
17621


5149
AGGCCAUG A UGGCCUUA
7976
TAAGGCCA GGCTAGCTACAACGA CATGGCCT
17622


5152
CCAUGAUG G CCUUACAC
7977
GTGTAAGG GGCTAGCTACAACGA CATCATGG
17623


5157
AUGGCCUU A CACUGAAA
843
TTTCAGTG GGCTAGCTACAACGA AAGGCCAT
17624


5159
GGCCUUAC A CUGAAAAU
5226
ATTTTCAG GGCTAGCTACAACGA GTAAGGCC
17625


5166
CACUGAAA A UGUCACAU
7978
ATGTGACA GGCTAGCTACAACGA TTTCAGTG
17626


5168
CUGAAAAU G UCACAUUC
7979
GAATGTGA GGCTAGCTACAACGA ATTTTCAG
17627


5171
AAAAUGUC A CAUUCUAU
5228
ATAGAATG GGCTAGCTACAACGA GACATTTT
17628


5173
AAUGUCAC A UUCUAUUU
5229
AAATAGAA GGCTAGCTACAACGA GTGACATT
17629


5178
CACAUUCU A UUUUGGGU
847
ACCCAAAA GGCTAGCTACAACGA AGAATGTG
17630


5185
UAUUUUGG G UAUUAAUA
7980
TATTAATA GGCTAGCTACAACGA CCAAAATA
17631


5187
UUUUGGGU A UUAAUAUA
851
UATATTAA GGCTAGCTACAACGA ACCCAAAA
17632


5191
GGGUAUUA A UAUAUAGU
7981
ACTATATA GGCTAGCTACAACGA TAATACCC
17633


5193
GUAUUAAU A UAUAGUCC
854
GGACTATA GGCTAGCTACAACGA ATTAATAC
17634


5195
AUUAAUAU A CAGUCCAG
855
CTGGACTA GGCTAGCTACAACGA ATATTAAT
17635


5198
AAUAUAUA G UCCAGACA
7982
TGTCTGGA GGCTAGCTACAACGA TATATATT
17636


5204
UAGUCCAG A CACUUAAC
7983
GTTAAGTG GGCTAGCTACAACGA CTGGACTA
17637


5206
GUCCAGAC A CUUAACUC
5233
GAGTTAAG GGCTAGCTACAACGA GTCTGGAC
17638


5211
GACACUUA A CUCAAUUU
7984
AAATTGAG GGCTAGCTACAACGA TAAGTGTC
17639


5216
UUAACUCA A UUUCUUGG
7985
CCAAGAAA GGCTAGCTACAACGA TGAGTTAA
17640


5224
AUUUCUUG G UAUUAUUC
7986
GAATAATA GGCTAGCTACAACGA CAAGAAAT
17641


5226
UUCUUGGU A UUAUUCUG
865
CAGAATAA GGCTAGCTACAACGA ACCAAGAA
17642


5229
UUGGUAUU A UUCUGUUU
867
AAACAGAA GGCTAGCTACAACGA AATACCAA
17643


5234
AUUAUUCU G UUUUGCAC
7987
GTGCAAAA GGCTAGCTACAACGA AGAATAAT
17644


5239
UCUGUUUU G CACAGUUA
7988
TAACTGTG GGCTAGCTACAACGA AAAACAGA
17645


5241
UGUUUUGC A CAGUUAGU
5239
ACTAACTG GGCTAGCTACAACGA GCAAAACA
17646


5244
UUUGCACA G UUAGUUGU
7989
ACAACTAA GGCTAGCTACAACGA TGTGCAAA
17647


5248
CACAGUUA G UUGUGAAA
7990
TTTCACAA GGCTAGCTACAACGA TAACTGTG
17648


5251
AGUUAGUU G UGAAAGAA
799
UTCTTTCA GGCTAGCTACAACGA AACTAACT
17649


5261
GAAAGAAA G CUGAGAAG
7992
CTTCTCAG GGCTAGCTACAACGA TTTCTTTC
17650


5271
UGAGAAGA A UGAAAAUG
7993
CATTTTCA GGCTAGCTACAACGA TCTTCTCA
17651


5277
GAAUGAAA A UGCAGUCC
7994
GGACTGCA GGCTAGCTACAACGA TTTCATTC
17652


5279
AUGAAAAU G CAGUCCUG
7995
CAGGACTG GGCTAGCTACAACGA ATTTTCAT
17653


5282
AAAAUGCA G UCCUGAGG
7996
CCTCAGGA GGCTAGCTACAACGA TGCATTTT
17654


5294
UGAGGAGA G UUUUCUCC
7997
GGAGAAAA GGCTAGCTACAACGA TCTCCTCA
17635


5303
UUUUCUCC A UAUCAAAA
5247
TTTTGATA GGCTAGCTACAACGA GGAGAAAA
17656


5305
UUCUCCAU A UCAAAACG
882
CGTTTTGA GGCTAGCTACAACGA ATGGAGAA
17657


5312
AUAUCAAA A CGAGGGCU
7998
AGCCCTCG GGCTAGCTACAACGA TTTGATAT
17658


5317
AAACGAGG G CUGAUGGA
7999
TCCATCAG GGCTAGCTACAACGA CCTCGTTT
17659


5321
GAGGGCUG A UGGAGGAA
8000
TTCCTCCA GGCTAGCTACAACGA CAGCCCTC
17660


5334
GGAAAAAG G UCAAUAAG
8001
CTTATTGA GGCTAGCTACAACGA CTTTTTCC
17661


5338
AAAGGUCA A UAAGGUCA
8002
TGACCTTA GGCTAGCTACAACGA TGACCTTT
17662


5343
UCAAUAAG G UCAAGGGA
8003
TCCCTTGA GGCTAGCTACAACGA CTTATTGA
17663


5354
AAGGGAAG A CCCCGUCU
8004
AGACGGGG GGCTAGCTACAACGA CTTCCCTT
17664


5359
AAGACCCC G UCUCUAUA
8005
TATAGAGA GGCTAGCTACAACGA GGGGTCTT
17665


5365
CCGUCUCU A UACCAACC
889
GGTTGGTA GGCTAGCTACAACGA AGAGACGG
17666


5367
GUCUCUAU A CCAACCAA
890
TTGGTTGG GGCTAGCTACAACGA ATAGAGAC
17667


5371
CUAUACCA A CCAAACCA
8006
TGGTTTGG GGCTAGCTACAACGA TGGTATAG
17668


5376
CCAACCAA A CCAAUUCA
8007
TGAATTGG GGCTAGCTACAACGA TTGGTTGG
17669


5380
CCAAACCA A UUCACCAA
8008
TTGGTGAA GGCTAGCTACAACGA TGGTTTGG
17670


5384
ACCAAUUC A CCAACACA
5263
TGTGTTGG GGCTAGCTACAACGA GAATTGGT
17671


5388
AUUCACCA A CACAGUUG
8009
CAACTGTG GGCTAGCTACAACGA TGGTGAAT
17672


5390
UCACCAAC A CAGUUGGG
5266
CCCAACTG GGCTAGCTACAACGA GTTGGTGA
17673


5393
CCAACACA G UUGGGACC
8010
GGTCCCAA GGCTAGCTACAACGA TGTGTTGG
17674


5399
CAGUUGGG A CCCAAAAC
8011
GTTTTGGG GGCTAGCTACAACGA CCCAACTG
17675


5406
GACCCAAA A CACAGGAA
8012
TTCCTGTG GGCTAGCTACAACGA TTTGGGTC
17676


5408
CCCAAAAC A CAGGAAGU
5271
ACTTCCTG GGCTAGCTACAACGA GTTTTGGG
17677


5415
CACAGGAA G UCAGUCAC
8013
GTGACTGA GGCTAGCTACAACGA TTCCTGTG
17678


5419
GGAAGUCA G UCACGUUU
8014
AAACGTGA GGCTAGCTACAACGA TGACTTCC
17679


5422
AGUCAGUC A CGUUUCCU
5274
AGGAAACG GGCTAGCTACAACGA GACTGACT
17680


5424
UCAGUCAC G UUUCCUUU
8015
AAAGGAAA GGCTAGCTACAACGA GTGACTGA
17681


5435
UCCUUUUC A UUUAAUGG
5277
CCATTAAA GGCTAGCTACAACGA GAAAAGGA
17682


5440
UUCAUUUA A UGGGGAUU
8016
AATCCCCA GGCTAGCTACAACGA TAAATGAA
17683


5446
UAAUGGGG A UUCCACUA
8017
TAGTGGAA GGCTAGCTACAACGA CCCCATTA
17684


5451
GGGAUUCC A CUAUCUCA
5279
TGAGATAG GGCTAGCTACAACGA GGAATCCC
17685


5454
AUUCCACU A UCUCACAC
908
GTGTGAGA GGCTAGCTACAACGA AGTGGAAT
17686


5459
ACUAUCUC A CACUAAUC
5282
GATTAGTG GGCTAGCTACAACGA GAGATAGT
17687


5461
UAUCUCAC A CUAAUCUG
5283
CAGATTAG GGCTAGCTACAACGA GTGAGATA
17688


5465
UCACACUA A UCUGAAAG
8018
CTTTCAGA GGCTAGCTACAACGA TAGTGTGA
17689


5475
CUGAAAGG A UGUGGAAG
8019
CTTCCACA GGCTAGCTACAACGA CCTTTCAG
17690


5477
GAAAGGAU G UGGAAGAG
8020
CTCTTCCA GGCTAGCTACAACGA ATCCTTTC
17691


5485
GUGGAAGA G CAUUAGCU
8021
AGCTAATG GGCTAGCTACAACGA TCTTCCAC
17692


5487
GGAAGAGC A UUAGCUGG
5286
CCAGCTAA GGCTAGCTACAACGA GCTCTTCC
17693


5491
GAGCAUUA G CUGGCGCA
8022
TGCGCCAG GGCTAGCTACAACGA TAATGCTC
17694


5495
AUUAGCUG G CGCAUAUU
8023
AATATGCG GGCTAGCTACAACGA CAGCTAAT
17695


5497
UAGCUGGC G CAUAUUAA
8024
TTAATATG GGCTAGCTACAACGA GCCAGCTA
17696


5499
GCUGGCGC A UAUUAAGC
5288
GCTTAATA GGCTAGCTACAACGA GCGCCAGC
17697


5501
UGGCGCAU A UUAAGCAC
915
GTGCTTAA GGCTAGCTACAACGA ATGCGCCA
17698


5506
CAUAUUAA G CACUUUAA
8025
TTAAAGTG GGCTAGCTACAACGA TTAATATG
17699


5508
UAUUAAGC A CUUUAAGC
5289
GCTTAAAG GGCTAGCTACAACGA GCTTAATA
17700


5515
CACUUUAA G CUCCUUGA
8026
TCAAGGAG GGCTAGCTACAACGA TTAAAGTG
17701


5524
CUCCUUGA G UAAAAAGG
8027
CCTTTTTA GGCTAGCTACAACGA TCAAGGAG
17702


5532
GUAAAAAG G UGGUAUGU
8028
ACATACCA GGCTAGCTACAACGA CTTTTTAC
17703


5535
AAAAGGUG G UAUGUAAU
8029
ATTACATA GGCTAGCTACAACGA CACCTTTT
17704


5537
AAGGUGGU A UGUAAUUU
924
AAATTACA GGCTAGCTACAACGA ACCACCTT
17705


5539
GGUGGUAU G UAAUUUAU
8030
ATAAATTA GGCTAGCTACAACGA ATACCACC
17706


5542
GGUAUGUA A UUUAUGCA
803
UGCATAAA GGCTAGCTACAACGA TACATACC
17707


5546
UGUAAUUU A UGCAAGGU
928
ACCTTGCA GGCTAGCTACAACGA AAATTACA
17708


5548
UAAUUUAU G CAAGGUAU
8032
ATACCTTG GGCTAGCTACAACGA ATAAATTA
17709


5553
UAUGCAAG G UAUUUCUC
8033
GAGAAATA GGCTAGCTACAACGA CTTGCATA
17710


5555
UGCAAGGU A UUUCUCCA
929
TGGAGAAA GGCTAGCTACAACGA ACCTTGCA
17711


5564
UUUCUCCA G UUGGGACU
8034
AGTCCCAA GGCTAGCTACAACGA TGGAGAAA
17712


5570
CAGUUGGG A CUCAGGAU
8035
ATCCTGAG GGCTAGCTACAACGA CCCAACTG
17713


5577
GACUCAGG A UAUUAGUU
8036
AACTAATA GGCTAGCTACAACGA CCTGAGTC
17714


5579
CUCAGGAU A UUAGUUAA
936
TTAACTAA GGCTAGCTACAACGA ATCCTGAG
17715


5583
GGAUAUUA G UUAAUGAG
8037
CTCATTAA GGCTAGCTACAACGA TAATATCC
17716


5587
AUUAGUUA A UGAGCCAU
8038
ATGGCTCA GGCTAGCTACAACGA TAACTAAT
17717


5591
GUUAAUGA G CCAUCACU
8039
AGTGATGG GGCTAGCTACAACGA TCATTAAC
17718


5594
AAUGAGCC A UCACUAGA
530
UCTAGTGA GGCTAGCTACAACGA GGCTCATT
17719


5597
GAGCCAUC A CUAGAAGA
5302
TCTTCTAG GGCTAGCTACAACGA GATGGCTC
17720


5609
GAAGAAAA G CCCAUUUU
8040
AAAATGGG GGCTAGCTACAACGA TTTTCTTC
17721


5613
AAAAGCCC A UUUUCAAC
5306
GTTGAAAA GGCTAGCTACAACGA GGGCTTTT
17722


5620
CAUUUUCA A CUGCUUUG
8041
CAAAGCAG GGCTAGCTACAACGA TGAAAATG
17723


5623
UUUCAACU G CUUUGAAA
8042
TTTCAAAG GGCTAGCTACAACGA AGTTGAAA
17724


5631
GCUUUGAA A CUUGCCUG
8043
CAGGCAAG GGCTAGCTACAACGA TTCAAAGC
17725


5635
UGAAACUU G CCUGGGGU
8044
ACCCCAGG GGCTAGCTACAACGA AAGTTTCA
17726


5642
UGCCUGGG C UCUGACCA
8045
TGCTCAGA GGCTAGCTACAACGA CCCAGGCA
17727


5648
GGGUCUGA C CAUGAUGG
8046
CCATCATG GGCTAGCTACAACGA TCAGACCC
17728


5650
GUCUGAGC A UGAUGGGA
5314
TCCCATCA GGCTAGCTACAACGA GCTCAGAC
17729


5653
UGACCAUG A UGGGAAUA
8047
TATTCCCA GGCTAGCTACAACGA CATGCTCA
17730


5659
UGAUGGGA A UAGGGAGA
8048
TCTCCCTA GGCTAGCTACAACGA TCCCATCA
17731


5667
AUAGGGAG A CAGGGUAG
8049
CTACCCTG GGCTAGCTACAACGA CTCCCTAT
17732


5672
GAGACAGG G UAGGAAAG
8050
CTTTCCTA GGCTAGCTACAACGA CCTGTCTC
17733


5682
AGGAAAGG G CGCCUACU
8051
AGTAGGCG GGCTAGCTACAACGA CCTTTCCT
17734


5684
GAAAGGGC G CCUACUCU
8052
AGAGTAGG GGCTAGCTACAACGA GCCCTTTC
17735


5688
GGGCGCCU A CUCUUCAG
953
CTGAAGAG GGCTAGCTACAACGA AGGCGCCC
17736


5698
UCUUCAGG G UCUAAAGA
8053
TCTTTAGA GGCTAGCTACAACGA CCTGAAGA
17737


5706
GUCUAAAG A UCAAGUGG
8054
CCACTTGA GGCTAGCTACAACGA CTTTAGAC
17738


5711
AAGAUCAA G UGGGCCUU
8055
AAGGCCCA GGCTAGCTACAACGA TTGATCTT
17739


5715
UCAAGUGG G CCUUGGAU
8056
ATCCAAGG GGCTAGCTACAACGA CCACTTGA
17740


5722
GGCCUUGG A UCGCUAAG
8057
CTTAGCGA GGCTAGCTACAACGA CCAAGGCC
17741


5725
CUUGGAUC G CUAAGCUG
8058
CAGCTTAG GGCTAGCTACAACGA GATCCAAG
17742


5730
AUCGCUAA C CUGGCUCU
8059
AGAGCCAG GGCTAGCTACAACGA TTAGCGAT
17743


5734
CUAAGCUG G CUCUGUUU
8060
AAACAGAG GGCTAGCTACAACGA CAGCTTAG
17744


5739
CUGGCUCU G UUUGAUGC
8061
GCATCAAA GGCTAGCTACAACGA AGAGCCAG
17745


5744
UCUGUUUG A UGCUAUUU
8062
AAATAGCA GGCTAGCTACAACGA CAAACAGA
17746


5746
UGUUUGAU G CUAUUUAU
8063
ATAAATAG GGCTAGCTACAACGA ATCAAACA
17747


5749
UUGAUGCU A UUUAUGCA
966
TGCATAAA GGCTAGCTACAACGA AGCATCAA
17748


5753
UCCUAUUU A UGCAAGUU
969
AACTTGCA GGCTAGCTACAACGA AAATAGCA
17749


5755
CUAUUUAU C CAAGUUAG
8064
CTAACTTG CGCTAGCTACAACGA ATAAATAG
17750


5759
UUAUGCAA G UUAGGGUC
8065
GACCCTAA GGCTAGCTACAACGA TTGCATAA
17751


5765
AAGUUAGG G UCUAUGUA
8066
TACATAGA GGCTAGCTACAACGA CCTAACTT
17752


5769
UAGGGUCU A UGUAUUUA
973
TAAATACA GGCTAGCTACAACGA AGACCCTA
17753


5771
GGGUCUAU G UAUUUAGG
8067
CCTAAATA GGCTAGCTACAACGA ATAGACCC
17754


5773
GUCUAUGU A UUUAGGAU
974
ATCCTAAA GGCTAGCTACAACGA ACATAGAC
17755


5780
UAUUUAGG A UGCGCCUA
8068
TAGGCGCA GGCTAGCTACAACGA CCTAAATA
17756


5782
UUUAGGAU G CGCCUACU
8069
AGTAGGCG GGCTAGCTACAACGA ATCCTAAA
17757


5784
UAGGAUGC G CCUACUCU
8070
AGAGTAGG GGCTAGCTACAACGA GCATCCTA
17758


5788
AUGCGCCU A CUCUUCAG
978
CTGAAGAG GGCTAGCTACAACGA AGGCGCAT
17759


5798
UCUUCAGG G UCUAAAGA
8053
TCTTTAGA GGCTAGCTACAACGA CCTGAAGA
17737


5806
GUCUAAAG A UCAAGUGG
8054
CCACTTCA GGCTAGCTACAACGA CTTTAGAC
17738


5811
AAGAUCAA G UGGGCCUU
8055
AAGGCCCA GGCTAGCTACAACGA TTGATCTT
17739


5815
UCAAGUGG G CCUUGGAU
8056
ATCCAAGG GGCTAGCTACAACGA CCACTTGA
17740


5822
GGCCUUGG A UCGCUAAG
8057
CTTAGCGA GGCTAGCTACAACGA CCAAGGCC
17741


5825
CUUGGAUC G CUAAGCUG
8058
CAGCTTAG GGCTAGCTACAACGA GATCCAAG
17742


5830
AUCGCUAA G CUGGCUCU
8059
AGAGCCAG GGCTAGCTACAACGA TTAGCGAT
17743


5834
CUAAGCUG G CUCUGUUU
8060
AAACAGAG GGCTAGCTACAACGA CAGCTTAG
17744


5839
CUGGCUCU G UUUGAUGC
8061
GCATCAAA GGCTAGCTACAACGA AGAGCCAG
17745


5844
UCUGUUUG A UGCUAUUU
8062
AAATAGCA GGCTAGCTACAACGA CAAACAGA
17746


5846
UGUUUGAU G CUAUUUAU
8063
ATAAATAG GGCTAGCTACAACGA ATCAAACA
17747


5849
UUGAUGCU A UUUAUGCA
966
TGCATAAA GGCTAGCTACAACGA AGCATCAA
17748


5853
UGCUAUUU A UGCAAGUU
969
AACTTGCA GGCTAGCTACAACGA AAATAGCA
17749


5855
CUAUUUAU G CAAGUUAG
8064
CTAACTTG GGCTAGCTACAACGA ATAAATAG
17750


5859
UUAUGCAA G UUAGGGUC
8065
GACCCTAA GGCTAGCTACAACGA TTGCATAA
17751


5865
AAGUUAGG G UCUAUGUA
8066
TACATAGA GGCTAGCTACAACGA CCTAACTT
17752


5869
UAGGGUCU A UGUAUUUA
973
TAAATACA GGCTAGCTACAACGA AGACCCTA
17753


5871
GGGUCUAU G UAUUUAGG
8067
CCTAAATA GGCTAGCTACAACGA ATAGACCC
17754


5873
GUCUAUGU A UUUAGGAU
974
ATCCTAAA GGCTAGCTACAACGA ACATAGAC
17755


5880
UAUUUAGG A UGUCUGCA
807
UGCAGACA GGCTAGCTACAACGA CCTAAATA
17760


5882
UUUAGGAU G UCUGCACC
8072
GGTGCAGA GGCTAGCTACAACGA ATCCTAAA
17761


5886
GGAUGUCU G CACCUUCU
8073
AGAAGGTG GGCTAGCTACAACGA AGACATCC
17762


5888
AUGUCUGC A CCUUCUGC
5335
GCAGAAGG GGCTAGCTACAACGA GCAGACAT
17763


5895
CACCUUCU G CAGCCAGU
8074
ACTGGCTG GGCTAGCTACAACGA AGAAGGTG
17764


5898
CUUCUGCA G CCAGUCAG
8075
CTGACTGG GGCTAGCTACAACGA TGCAGAAG
17765


5902
UGCAGCCA G UCAGAAGC
8076
GCTTCTGA GGCTAGCTACAACGA TGGCTGCA
17766


5909
AGUCAGAA G CUGGAGAG
8077
CTCTCCAG GGCTAGCTACAACGA TTCTGACT
17767


5918
CUGGAGAG G CAACAGUG
8078
CACTGTTG GGCTAGCTACAACGA CTCTCCAG
17768


5921
GAGAGGCA A CAGUGGAU
8079
ATCCACTG GGCTAGCTACAACGA TGCCTCTC
17769


5924
AGGCAACA G UGGAUUGC
8080
GCAATCCA GGCTAGCTACAACGA TGTTGCCT
17770


5928
AACAGUGG A UUGCUGCU
8081
AGCAGCAA GGCTAGCTACAACGA CCACTGTT
17771


5931
AGUGGAUU G CUGCUUCU
8082
AGAAGCAG GGCTAGCTACAACGA AATCCACT
17772


5934
GGAUUGCU G CUUCUUGG
8083
CCAAGAAG GGCTAGCTACAACGA AGCAATCC
17773


5951
GGAGAAGA G UAUGCUUC
8084
GAAGCATA GGCTAGCTACAACGA TCTTCTCC
17774


5953
AGAAGAGU A UGCUUCCU
990
AGGAAGCA GGCTAGCTACAACGA ACTCTTCT
17775


5955
AAGAGUAU G CUUCCUUU
8085
AAAGGAAG GGCTAGCTACAACGA ATACTCTT
17776


5965
UUCCUUUU A UCCAUGUA
996
TACATGGA GGCTAGCTACAACGA AAAAGGAA
17777


5969
UUUUAUCC A UGUAAUUU
5353
AAATTACA GGCTAGCTACAACGA GGATAAAA
17778


5971
UUAUCCAU G UAAUUUAA
8086
TTAAATTA GGCTAGCTACAACGA ATGGATAA
17779


5974
UCCAUGUA A UUUAACUG
8087
CAGTTAAA GGCTAGCTACAACGA TACATGGA
17780


5979
GUAAUUUA A CUGUAGAA
8088
TTCTACAG GGCTAGCTACAACGA TAAATTAC
17781


5982
AUUUAACU G UAGAACCU
8089
AGGTTCTA GGCTAGCTACAACGA AGTTAAAT
17782


5987
ACUGUAGA A CCUGAGCU
8090
AGCTCAGG GGCTAGCTACAACGA TCTACAGT
17783


5993
GAACCUGA G CUCUAAGU
8091
ACTTAGAG GGCTAGCTACAACGA TCAGGTTC
17784


6000
AGCUCUAA G UAACCGAA
8092
TTCGGTTA GGCTAGCTACAACGA TTAGAGCT
17785


6003
UCUAAGUA A CCGAAGAA
8093
TTCTTCGG GGCTAGCTACAACGA TACTTAGA
17786


6011
ACCGAAGA A UGUAUGCC
8094
GGCATACA GGCTAGCTACAACGA TCTTCGGT
17787


6013
CGAAGAAU G UAUGCCUC
8095
GAGGCATA GGCTAGCTACAACGA ATTCTTCG
17788


6015
AAGAAUGU A UGCCUCUG
1006
CAGAGGCA GGCTAGCTACAACGA ACATTCTT
17789


6017
GAAUGUAU G CCUCUGUU
8096
AACAGAGG GGCTAGCTACAACGA ATACATTC
17790


6023
AUGCCUCU G UUCUUAUG
8097
CATAAGAA GGCTAGCTACAACGA AGAGGCAT
17791


6029
CUGUUCUU A UGUGCCAC
1011
GTGGCACA GGCTAGCTACAACGA AAGAACAG
17792


6031
GUUCUUAU G UGCCACAU
8098
ATGTGGCA GGCTAGCTACAACGA ATAAGAAC
17793


6033
UCUUAUGU G CCACAUCC
8099
GGATGTGG GGCTAGCTACAACGA ACATAAGA
17794


6036
UAUGUGCC A CAUCCUUG
5365
CAAGGATG GGCTAGCTACAACGA GGCACATA
17795


6038
UGUGCCAC A UCCUUGUU
5366
AACAAGGA GGCTAGCTACAACGA GTGGCACA
17796


6044
ACAUCCUU G UUUAAAGG
8100
CCTTTAAA GGCTAGCTACAACGA AAGGATGT
17797


6052
GUUUAAAG G CUCUCUGU
8101
ACAGAGAG GGCTAGCTACAACGA CTTTAAAC
17798


6059
GGCUCUCU G UAUGAAGA
8102
TCTTCATA GGCTAGCTACAACGA AGAGAGCC
17799


6061
CUCUCUGU A UGAAGAGA
1019
TCTCTTCA GGCTAGCTACAACGA ACAGAGAG
17800


6069
AUGAAGAG A UGGGACCG
8103
CGGTCCCA GGCTAGCTACAACGA CTCTTCAT
17801


6074
GAGAUGGG A CCGUCAUC
8104
GATGACGG GGCTAGCTACAACGA CCCATCTC
17802


6077
AUGGGACC G UCAUCAGC
8105
GCTGATGA GGCTAGCTACAACGA GGTCCCAT
17803


6080
GGACCGUC A UCAGCACA
5373
TGTGCTGA GGCTAGCTACAACGA GACGGTCC
17804


6084
CGUCAUCA G CACAUUCC
8106
GGAATGTG GGCTAGCTACAACGA TGATGACG
17805


6086
UCAUCAGC A CAUUCCCU
5375
AGGGAATG GGCTAGCTACAACGA GCTGATGA
17806


6088
AUCAGCAC A UUCCCUAG
5376
CTAGGGAA GGCTAGCTACAACGA GTGCTGAT
17807


6096
AUUCCCUA G UGAGCCUA
8107
TAGGCTCA GGCTAGCTACAACGA TAGGGAAT
17808


6100
CCUAGUGA G CCUACUGG
8108
CCAGTAGG GGCTAGCTACAACGA TCACTAGG
17809


6104
GUGAGCCU A CUGGCUCC
1025
GGAGCCAG GGCTAGCTACAACGA AGGCTCAC
17810


6108
GCCUACUG G CUCCUGGC
8109
GCCAGGAG GGCTAGCTACAACGA CAGTAGGC
17811


6115
GGCUCCUG G CAGCGGCU
8110
AGCCGCTG GGCTAGCTACAACGA CAGGAGCC
17812


6118
UCCUGGCA G CGGCUUUU
8111
AAAAGCCG GGCTAGCTACAACGA TGCCAGGA
17813


6121
UGGCAGCG G CUUUUGUG
8112
CACAAAAG GGCTAGCTACAACGA CGCTGCCA
17814


6127
CGGCUUUU G UGGAAGAC
8113
GTCTTCCA GGCTAGCTACAACGA AAAAGCCG
17815


6134
UGUGGAAG A CUCACUAG
8114
CTAGTGAG GGCTAGCTACAACGA CTTCCACA
17816


6138
GAAGACUC A CUAGCCAG
5389
CTGGCTAG GGCTAGCTACAACGA GAGTCTTC
17817


6142
ACUCACUA G CCAGAAGA
8115
TCTTCTGG GGCTAGCTACAACGA TAGTGAGT
17818


6156
AGAGAGGA G UGGGACAG
8116
CTGTCCCA GGCTAGCTACAACGA TCCTCTCT
17819


6161
GGAGUGGG A CAGUCCUC
8117
GAGGACTG GGCTAGCTACAACGA CCCACTCC
17820


6164
GUGGGACA G UCCUCUCC
8118
GGAGAGGA GGCTAGCTACAACGA TGTCCCAC
17821


6173
UCCUCUCC A CCAAGAUC
5398
GATCTTGG GGCTAGCTACAACGA GGAGAGGA
17822


6179
CCACCAAG A UCUAAAUC
8119
GATTTAGA GGCTAGCTACAACGA CTTGGTGG
17823


6185
AGAUCUAA A UCCAAACA
8120
TGTTTGGA GGCTAGCTACAACGA TTAGATCT
17824


6191
AAAUCCAA A CAAAAGCA
812
UGCTTTTG GGCTAGCTACAACGA TTGGATTT
17825


6197
AAACAAAA G CAGGCUAG
8122
CTAGCCTG GGCTAGCTACAACGA TTTTGTTT
17826


6201
AAAAGCAG G CUAGAGCC
8123
GGCTCTAG GGCTAGCTACAACGA CTGCTTTT
17827


6207
AGGCUAGA G CCAGAAGA
8124
TCTTCTGG GGCTAGCTACAACGA TCTAGCCT
17828


6220
AAGAGAGG A CAAAUCUU
8125
AAGATTTG GGCTAGCTACAACGA CCTCTCTT
17829


6224
GAGGACAA A UCUUUGUU
8126
AACAAAGA GGCTAGCTACAACGA TTGTCCTC
17830


6230
AAAUCUUU G UUGUUCCU
8127
AGGAACAA GGCTAGCTACAACGA AAAGATTT
17831


6233
UCUUUGUU G UUCCUCUU
8128
AAGAGGAA GGCTAGCTACAACGA AACAAAGA
17832


6246
UCUUCUUU A CACAUACG
1050
CGTATGTG GGCTAGCTACAACGA AAAGAAGA
17833


6248
UUCUUUAC A CAUACGCA
5415
TGCGTATG GGCTAGCTACAACGA GTAAAGAA
17834


6250
CUUUACAC A UACGCAAA
5416
TTTGCGTA GGCTAGCTACAACGA GTGTAAAG
17835


6252
UUACACAU A CGCAAACC
1051
GGTTTGCG GGCTAGCTACAACGA ATGTGTAA
17836


6254
ACACAUAC G CAAACCAC
8129
GTGGTTTG GGCTAGCTACAACGA GTATGTGT
17837


6258
AUACGCAA A CCACCUGU
8130
ACAGGTGG GGCTAGCTACAACGA TTGCGTAT
17838


6262
CGCAAACC A CCUGUGAC
5419
GTCACAGG GGCTAGCTACAACGA GGTTTGCG
17839


6265
AACCACCU G UGACAGCU
8131
AGCTGTCA GGCTAGCTACAACGA AGGTGGTT
17840


6268
CACCUGUG A CACCUGGG
8132
GCCAGCTG GGCTAGCTACAACGA CACAGGTG
17841


6271
CUGUGACA G CUGGCAAU
8133
ATTGCCAG GGCTAGCTACAACGA TGTCACAG
17842


6275
GACACCUG G CAAUUUUA
8134
TAAAATTG GGCTAGCTACAACGA CAGCTGTC
17843


6278
AGCUGGCA A UUUUAUAA
8135
TTATAAAA GGCTAGCTACAACGA TGCCAGCT
17844


6283
GCAAUUUU A UAAAUCAG
1055
CTGATTTA GGCTAGCTACAACGA AAAATTGC
17845


6287
UUUUAUAA A UCAGGUAA
8136
TTACCTGA GGCTAGCTACAACGA TTATAAAA
17846


6292
UAAAUCAG G UAACUGGA
8137
TCCAGTTA GGCTAGCTACAACGA CTGATTTA
17847


6295
AUCAGGUA A CUGGAAGG
8138
CCTTCCAG GGCTAGCTACAACGA TACCTGAT
17848


6306
GGAAGGAG G UUAAACUC
8139
GAGTTTAA GGCTAGCTACAACGA CTCCTTCC
17849


6311
GAGGUUAA A CUCAGAAA
8140
TTTCTGAG GGCTAGCTACAACGA TTAACCTC
17850


6327
AAAAGAAG A CCUCAGUC
8141
GACTGAGG GGCTAGCTACAACGA CTTCTTTT
17851


6333
AGACCUCA G UCAAUUCU
8142
AGAATTGA GGCTAGCTACAACGA TGAGGTCT
17852


6337
CUCAGUCA A UUCUCUAC
8143
GTAGAGAA GGCTAGCTACAACGA TGACTGAG
17853


6344
AAUUCUCU A CUUUUUUU
1067
AAAAAAAG GGCTAGCTACAACGA AGAGAATT
17854


6366
UUUUCCAA A UCAGAUAA
8144
TTATCTGA GGCTAGCTACAACGA TTGGAAAA
17855


6371
CAAAUCAG A UAAUAGCC
8145
GGCTATTA GGCTAGCTACAACGA CTGATTTG
17856


6374
AUCAGAUA A UAGCCCAG
8146
CTGGGCTA GGCTAGCTACAACGA TATCTGAT
17857


6377
AGAUAAUA G CCCAGCAA
8147
TTGCTGGG GGCTAGCTACAACGA TATTATCT
17858


6382
AUAGCCCA G CAAAUAGU
8148
ACTATTTG GGCTAGCTACAACGA TGGGCTAT
17859


6386
CCCAGCAA A UAGUGAUA
8149
TATCACTA GGCTAGCTACAACGA TTGCTGGG
17860


6389
AGCAAAUA G UGAUAACA
8150
TGTTATCA GGCTAGCTACAACGA TATTTGCT
17861


6392
AAAUAGUG A UAACAAAU
8151
ATTTGTTA GGCTAGCTACAACGA CACTATTT
17862


6395
UAGUGAUA A CAAAUAAA
8152
TTTATTTG GGCTAGCTACAACGA TATCACTA
17863


6399
GAUAACAA A UAAAACCU
8153
AGGTTTTA GGCTAGCTACAACGA TTGTTATC
17864


6404
CAAAUAAA A CCUUAGCU
8154
AGCTAAGG GGCTAGCTACAACGA TTTATTTG
17865


6410
AAACCUUA G CUGUUCAU
8155
ATGAACAG GGCTAGCTACAACGA TAAGGTTT
17866


6413
CCUUAGCU G UUCAUGUC
8156
GACATGAA GGCTAGCTACAACGA AGCTAAGG
17867


6417
AGCUGUUC A UGUCUUGA
5447
TCAAGACA GGCTAGCTACAACGA GAACAGCT
17868


6419
CUGUUCAU G UCUUGAUU
8157
AATCAAGA GGCTAGCTACAACGA ATGAACAG
17869


6425
AUGUCUUG A UUUCAAUA
8158
TATTGAAA GGCTAGCTACAACGA CAAGACAT
17870


6431
UGAUUUCA A UAAUUAAU
8159
ATTAATTA GGCTAGCTACAACGA TGAAATCA
17871


6434
UUUCAAUA A UUAAUUCU
8160
AGAATTAA GGCTAGCTACAACGA TATTGAAA
17872


6438
AAUAAUUA A UUCUUAAU
8161
ATTAAGAA GGCTAGCTACAACGA TAATTATT
17873


6445
AAUUCUUA A UCAUUAAG
8162
CTTAATGA GGCTAGCTACAACGA TAAGAATT
17874


6448
UCUUAAUC A UUAAGAGA
545
UCTCTTAA GGCTAGCTACAACGA GATTAAGA
17875


6456
AUUAAGAG A CCAUAAUA
8163
TATTATGG GGCTAGCTACAACGA CTCTTAAT
17876


6459
AAGAGACC A UAAUAAAU
5453
ATTTATTA GGCTAGCTACAACGA GGTCTCTT
17877


6462
AGACCAUA A UAAAUACU
8164
AGTATTTA GGCTAGCTACAACGA TATGGTCT
17878


6466
CAUAAUAA A UACUCCUU
8165
AAGGAGTA GGCTAGCTACAACGA TTATTATG
17879


6468
UAAUAAAU A CUCCUUUU
1111
AAAAGGAG GGCTAGCTACAACGA ATTTATTA
17880


6487
AGAGAAAA G CAAAACCA
8166
TGGTTTTG GGCTAGCTACAACGA TTTTCTCT
17881


6492
AAAGCAAA A CCAUUAGA
8167
TCTAATGG GGCTAGCTACAACGA TTTGCTTT
17882


6495
GCAAAACC A UUAGAAUU
5460
AATTCTAA GGCTAGCTACAACGA GGTTTTGC
17883


6501
CCAUUAGA A UUGUUACU
8168
AGTAACAA GGCTAGCTACAACGA TCTAATGG
17884


6504
UUAGAAUU G UUACUCAG
8169
CTGAGTAA GGCTAGCTACAACGA AATTCTAA
17885


6507
GAAUUGUU A CUCAGCUC
1121
GAGCTGAG GGCTAGCTACAACGA AACAATTC
17886


6512
GUUACUCA G CUCCUUCA
8170
TGAAGGAG GGCTAGCTACAACGA TGAGTAAC
17887


6522
UCCUUCAA A CUCAGGUU
8171
AACCTGAG GGCTAGCTACAACGA TTGAAGGA
17888


6528
AAACUCAG G UUUGUAGC
8172
GCTACAAA GGCTAGCTACAACGA CTGAGTTT
17889


6532
UCAGGUUU G UAGCAUAC
8173
GTATGCTA GGCTAGCTACAACGA AAACCTGA
17890


6535
GGUUUGUA G CAUACAUG
8174
CATGTATG GGCTAGCTACAACGA TACAAACC
17891


6537
UUUGUAGC A UACAUGAG
5469
CTCATGTA GGCTAGCTACAACGA GCTACAAA
17892


6539
UGUAGCAU A CAUGAGUC
1130
GACTCATG GGCTAGCTACAACGA ATGCTACA
17893


6541
UAGCAUAC A UGAGUCCA
5470
TGGACTCA GGCTAGCTACAACGA GTATGCTA
17894


6545
AUACAUGA G UCCAUCCA
8175
TGGATGGA GGCTAGCTACAACGA TCATGTAT
17895


6549
AUGAGUCC A UCCAUCAG
5472
CTGATGGA GGCTAGCTACAACGA GGACTCAT
17896


6553
GUCCAUCC A UCAGUCAA
5474
TTGACTGA GGCTAGCTACAACGA GGATGGAC
17897


6557
AUCCAUCA G UCAAAGAA
8176
TTCTTTGA GGCTAGCTACAACGA TGATGGAT
17898


6565
GUCAAAGA A UGGUUCCA
8177
TGGAACCA GGCTAGCTACAACGA TCTTTGAC
17899


6568
AAAGAAUG G UUCCAUCU
8178
AGATGGAA GGCTAGCTACAACGA CATTCTTT
17900


6573
AUGGUUCC A UCUGGAGU
5478
ACTCCAGA GGCTAGCTACAACGA GGAACCAT
17901


6580
CAUCUGGA G UCUUAAUG
8179
CATTAAGA GGCTAGCTACAACGA TCCAGATG
17902


6586
GAGUCUUA A UGUAGAAA
8180
TTTCTACA GGCTAGCTACAACGA TAAGACTC
17903


6588
GUCUUAAU G UAGAAAGA
818
UCTTTCTA GGCTAGCTACAACGA ATTAAGAC
17904


6600
AAAGAAAA A UGGAGACU
8182
AGTCTCCA GGCTAGCTACAACGA TTTTCTTT
17905


6606
AAAUGGAG A CUUGUAAU
8183
ATTACAAG GGCTAGCTACAACGA CTCCATTT
17906


6610
GGAGACUU G UAAUAAUG
8184
CATTATTA GGCTAGCTACAACGA AAGTCTCC
17907


6613
GACUUGUA A UAAUGAGC
8185
GCTCATTA GGCTAGCTACAACGA TACAAGTC
17908


6616
UUGUAAUA A UGAGCUAG
8186
CTAGCTCA GGCTAGCTACAACGA TATTACAA
17909


6620
AAUAAUGA G CUAGUUAC
8187
GTAACTAG GGCTAGCTACAACGA TCATTATT
17910


6624
AUGAGCUA G UUACAAAG
8188
CTTTGTAA GGCTAGCTACAACGA TAGCTCAT
17911


6627
AGCUAGUU A CAAAGUGC
1147
GCACTTTG GGCTAGCTACAACGA AACTAGCT
17912


6632
GUUACAAA G UGCUUGUU
8189
AACAAGCA GGCTAGCTACAACGA TTTGTAAC
17913


6634
UACAAAGU G CUUGUUCA
8190
TGAACAAG GGCTAGCTACAACGA ACTTTGTA
17914


6638
AAGUGCUU G UUCAUUAA
819
UTAATGAA GGCTAGCTACAACGA AAGCACTT
17915


6642
GCUUGUUC A UUAAAAUA
5485
TATTTTAA GGCTAGCTACAACGA GAACAAGC
17916


6648
UCAUUAAA A UAGCACUG
8192
CAGTGCTA GGCTAGCTACAACGA TTTAATGA
17917


6651
UUAAAAUA G CACUGAAA
8193
TTTCAGTG GGCTAGCTACAACGA TATTTTAA
17918


6653
AAAAUAGC A CUGAAAAU
5486
ATTTTCAG GGCTAGCTACAACGA GCTATTTT
17919


6660
CACUGAAA A UUGAAACA
8194
TGTTTCAA GGCTAGCTACAACGA TTTCAGTG
17920


6666
AAAUUGAA A CAUGAAUU
8195
AATTCATG GGCTAGCTACAACGA TTCAATTT
17921


6668
AUUGAAAC A UGAAUUAA
5488
TTAATTCA GGCTAGCTACAACGA GTTTCAAT
17922


6672
AAACAUGA A UUAACUGA
8196
TCAGTTAA GGCTAGCTACAACGA TCATGTTT
17923


6676
AUGAAUUA A CUGAUAAU
8197
ATTATCAG GGCTAGCTACAACGA TAATTCAT
17924


6680
AUUAACUG A UAAUAUUC
8198
GAATATTA GGCTAGCTACAACGA CAGTTAAT
17925


6683
AACUGAUA A UAUUCCAA
8199
TTGGAATA GGCTAGCTACAACGA TATCAGTT
17926


6685
CUGAUAAU A UUCCAAUC
1158
GATTGGAA GGCTAGCTACAACGA ATTATCAG
17927


6691
AUAUUCCA A UCAUUUGC
8200
GCAAATGA GGCTAGCTACAACGA TGGAATAT
17928


6694
UUCCAAUC A UUUGCCAU
5492
ATGGCAAA GGCTAGCTACAACGA GATTGGAA
17929


6698
AAUCAUUU G CCAUUUAU
8201
ATAAATGG GGCTAGCTACAACGA AAATGATT
17930


6701
CAUUUGCC A UUUAUGAC
5494
GTCATAAA GGCTAGCTACAACGA GGCAAATG
17931


6705
UGCCAUUU A UGACAAAA
1166
TTTTGTCA GGCTAGCTACAACGA AAATGGCA
17932


6708
CAUUUAUG A CAAAAAUG
8202
CATTTTTG GGCTAGCTACAACGA CATAAATG
17933


6714
UGACAAAA A UGGUUGGC
8203
GCCAACCA GGCTAGCTACAACGA TTTTGTCA
17934


6717
CAAAAUUG G UUGGCACU
8204
AGTGCCAA GGCTAGCTACAACGA CATTTTTG
17935


6721
AAUGGUUG G CACUAACA
8205
TGTTAGTG GGCTAGCTACAACGA CAACCATT
17936


6723
UGGUUGGC A CUAACAAA
5496
TTTGTTAG GGCTAGCTACAACGA GCCAACCA
17937


6727
UGGCACUA A CAAAGAAC
8206
GTTCTTTG GGCTAGCTACAACGA TAGTGCCA
17938


6734
AACAAAGA A CGAGCACU
8207
AGTGCTCG GGCTAGCTACAACGA TCTTTGTT
17939


6738
AAGAACGA G CACUUCCU
8208
AGGAAGTG GGCTAGCTACAACGA TCGTTCTT
17940


6740
GAACGAGC A CUUCCUUU
5499
AAAGGAAG GGCTAGCTACAACGA GCTCGTTC
17941


6753
CUUUCAGA G UUUCUGAG
8209
CTCAGAAA GGCTAGCTACAACGA TCTGAAAG
17942


6762
UUUCUGAG A UAAUGUAC
8210
GTACATTA GGCTAGCTACAACGA CTCAGAAA
17943


6765
CUGAGAUA A UGUACGUG
8211
CACGTACA GGCTAGCTACAACGA TATCTCAG
17944


6767
GAGAUAAU G UACGUGGA
8212
TCCACGTA GGCTAGCTACAACGA ATTATCTC
17945


6769
GAUAAUGU A CGUGGAAC
1178
GTTCCACG GGCTAGCTACAACGA ACATTATC
17946


6771
UAAUGUAC G UGGAACAG
8213
CTGTTCCA GGCTAGCTACAACGA GTACATTA
17947


6776
UACGUGGA A CAGUCUGG
8214
CCAGACTG GGCTAGCTACAACGA TCCACGTA
17948


6779
GUGGAACA G UCUGGGUG
8215
CACCCAGA GGCTAGCTACAACGA TGTTCCAC
17949


6785
CAGUCUGG G UGGAAUGG
8216
CCATTCCA GGCTAGCTACAACGA CCAGACTG
17950


6790
UGGGUGGA A UGGGGCUG
8217
CAGCCCCA GGCTAGCTACAACGA TCCACCCA
17951


6795
GGAAUGGG G CUGAAACC
8218
GGTTTCAG GGCTAGCTACAACGA CCCATTCC
17952


6801
GGGCUGAA A CCAUGUGC
8219
GCACATGG GGCTAGCTACAACGA TTCAGCCC
17953


6804
CUGAAACC A UGUGCAAG
5509
CTTGCACA GGCTAGCTACAACGA GGTTTCAG
17954


6806
GAAACCAU G UGCAAGUC
8220
GACTTGCA GGCTAGCTACAACGA ATGGTTTC
17955


6808
AACCAUGU G CAAGUCUG
8221
CAGACTTG GGCTAGCTACAACGA ACATGGTT
17956


6812
AUGUGCAA G UCUGUGUC
8222
GACACAGA GGCTAGCTACAACGA TTGCACAT
17957


6816
GCAAGUCU G UGUCUUGU
8223
ACAAGACA GGCTAGCTACAACGA AGACTTGC
17958


6818
AAGUCUGU G UCUUGUCA
8224
TGACAAGA GGCTAGCTACAACGA ACAGACTT
17959


6823
UGUGUCUU G UCAGUCCA
8225
TGGACTGA GGCTAGCTACAACGA AAGACACA
17960


6827
UCUUGUCA G UCCAAGAA
8226
TTCTTGGA GGCTAGCTACAACGA TGACAAGA
17961


6836
UCCAAGAA C UGACACCG
8227
CGGTGTCA GGCTAGCTACAACGA TTCTTGGA
17962


6839
AAGAAGUG A CACCGAGA
8228
TCTCGGTG GGCTAGCTACAACGA CACTTCTT
17963


6841
GAAGUGAC A CCGAGAUG
5516
CATCTCGG GGCTAGCTACAACGA GTCACTTC
17964


6847
ACACCGAG A UGUUAAUU
8229
AATTAACA GGCTAGCTACAACGA CTCGGTGT
17965


6849
ACCGAGAU C UUAAUUUU
8230
AAAATTAA GGCTAGCTACAACGA ATCTCGGT
17966


6853
AGAUGUUA A UUUUAGGG
8231
CCCTAAAA GGCTAGCTACAACGA TAACATCT
17967


6862
UUUUAGGG A CCCGUGCC
8232
GGCACGGG GGCTAGCTACAACGA CCCTAAAA
17968


6866
AGGGACCC G UGCCUUGU
8233
ACAAGGCA GGCTAGCTACAACGA GGGTCCCT
17969


6868
GGACCCGU C CCUUGUUU
8234
AAACAAGG GGCTAGCTACAACGA ACGGGTCC
17970


6873
CGUGCCUU G UUUCCUAG
8235
CTAGGAAA GGCTAGCTACAACGA AAGGCACG
17971


6881
GUUUCCUA G CCCACAAG
8236
CTTGTGGG GGCTAGCTACAACGA TAGGAAAC
17972


6885
CCUAGCCC A CAAGAAUG
5526
CATTCTTG GGCTAGCTACAACGA GCGCTAGG
17973


6891
CCACAAGA A UGCAAACA
8237
TGTTTGCA GGCTAGCTACAACGA TCTTGTGG
17974


6893
ACAAGAAU G CAAACAUC
8238
GATGTTTG GGCTAGCTACAACGA ATTCTTGT
17975


6897
GAAUGCAA A CAUCAAAC
8239
GTTTGATG GGCTAGCTACAACGA TTGCATTC
17976


6899
AUGCAAAC A UCAAACAG
5529
CTCTTTGA GGCTAGCTACAACGA GTTTGCAT
17977


6904
AACAUCAA A CAGAUACU
8240
AGTATCTG GGCTAGCTACAACGA TTGATGTT
17978


6908
UCAAACAG A UACUCGCU
8241
AGCGAGTA GGCTAGCTACAACGA CTGTTTGA
17979


6910
AAACAGAU A CUCGCUAG
1197
CTAGCGAG GGCTAGCTACAACGA ATCTGTTT
17980


6914
AGAUACUC G CUAGCCUC
8242
GAGGCTAG GGCTAGCTACAACGA GAGTATCT
17981


6918
ACUCGCUA G CCUCAUUU
8243
AAATGAGG GGCTAGCTACAACGA TAGCGAGT
17982


6923
CUAGCCUC A UUUAAAUU
5536
AATTTAAA GGCTAGCTACAACGA GAGGCTAG
17983


6929
UCAUUUAA A UUGAUUAA
8244
TTAATCAA GGCTAGCTACAACGA TTAAATGA
17984


6933
UUAAAUUG A UUAAAGGA
8245
TCCTTTAA GGCTAGCTACAACGA CAATTTAA
17985


6945
AAGGAGGA G UGCAUCUU
8246
AAGATGCA GGCTAGCTACAACGA TCCTCCTT
17986


6947
GGAGGAGU G CAUCUUUG
8247
CAAAGATG GGCTAGCTACAACGA ACTCCTCC
17987


6949
AGGAGUGC A UCUUUGGC
5537
GCCAAAGA GGCTAGCTACAACGA GCACTCCT
17988


6956
CAUCUUUG G CCGACAGU
8248
ACTGTCGG GGCTAGCTACAACGA CAAAGATG
17989


6960
UUUGGCCG A CAGUGGUG
8249
CACCACTG GGCTAGCTACAACGA CGGCCAAA
17990


6963
GGCCGACA G UGGUGUAA
8250
TTACACCA GGCTAGCTACAACGA TGTCGGCC
17991


6966
CGACAGUG G UGUAACUG
8251
CAGTTACA GGCTAGCTACAACGA CACTGTCG
17992


6968
ACAGUGGU C UAACUGUG
8252
CACAGTTA GGCTAGCTACAACGA ACCACTGT
17993


6971
GUGGUGUA A CUGUGUGU
8253
ACACACAG GGCTAGCTACAACGA TACACCAC
17994


6974
GUGUAACU G UGUGUGUG
8254
CACACACA GGCTAGCTACAACGA AGTTACAC
17995


6976
GUAACUGU G UGUGUGUG
8255
CACACACA GGCTAGCTACAACGA ACAGTTAC
17996


6978
AACUGUGU G UGUGUGUG
8256
CACACACA GGCTAGCTACAACGA ACACAGTT
17997


6980
CUGUGUGU G UGUGUGUG
8257
CACACACA GGCTAGCTACAACGA ACACACAG
17998


6982
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6984
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6986
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6988
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6990
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6992
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6994
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6996
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


6998
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


7000
GUGUGUGU C UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


7002
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


7004
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


7006
GUGUGUGU G UGUGUGUG
8258
CACACACA GGCTAGCTACAACGA ACACACAC
17999


7008
GUGUGUGU C UGUGUGGG
8259
CCCACACA GGCTAGCTACAACGA ACACACAC
18000


7010
GUGUGUGU G UGUGGGUG
8260
CACCCACA GGCTAGCTACAACGA ACACACAC
18001


7012
GUGUGUGU G UGGGUGUG
8261
CACACCCA GGCTAGCTACAACGA ACACACAC
18002


7016
GUGUGUGG C UGUGGGUG
8262
CACCCACA GGCTAGCTACAACGA CCACACAC
18003


7018
GUGUGGGU G UGGGUGUA
8263
TACACCCA GGCTAGCTACAACGA ACCCACAC
18004


7022
GGGUGUGG C UGUAUGUG
8264
CACATACA GGCTAGCTACAACGA CCACACCC
18005


7024
GUGUGGGU G UAUGUGUG
8265
CACACATA GGCTAGCTACAACGA ACCCACAC
18006


7026
GUGGGUGU A UGUGUGUU
1211
AACACACA GGCTAGCTACAACGA ACACCCAC
18007


7028
GGGUGUAU C UGUGUUUU
8266
AAAACACA GGCTAGCTACAACGA ATACACCC
18008


7030
GUGUAUGU C UGUUUUGU
8267
ACAAAACA GGCTAGCTACAACGA ACATACAC
18009


7032
GUAUGUGU G UUUUGUGC
8268
GCACAAAA GGCTAGCTACAACGA ACACATAC
18010


7037
UGUGUUUU C UGCAUAAC
8269
GTTATGCA GGCTAGCTACAACGA AAAACACA
18011


7039
UGUUUUGU C CAUAACUA
8270
TAGTTATG GGCTAGCTACAACGA ACAAAACA
18012


7041
UUUUGUGC A UAACUAUU
5542
AATAGTTA GGCTAGCTACAACGA GCACAAAA
18013


7044
UGUGCAUA A CUAUUUAA
827
UTAAATAG GGCTAGCTACAACGA TATGCACA
18014


7047
GCAUAACU A UUUAAGGA
1216
TCCTTAAA GGCTAGCTACAACGA AGTTATGC
18015


7057
UUAAGGAA A CUGGAAUU
8272
AATTCCAG GGCTAGCTACAACGA TTCCTTAA
18016


7063
AAACUGGA A UUUUAAAG
8273
CTTTAAAA GGCTAGCTACAACGA TCCAGTTT
18017


7071
AUUUUAAA G UUACUUUU
8274
AAAAGTAA GGCTAGCTACAACGA TTTAAAAT
18018


7074
UUAAAGUU A CUUUUAUA
1225
TATAAAAG GGCTAGCTACAACGA AACTTTAA
18019


7080
UUACUUUU A UACAAACC
1229
GGTTTGTA GGCTAGCTACAACGA AAAAGTAA
18020


7082
ACUUUUAU A CAAACCAA
1230
TTGGTTTG GGCTAGCTACAACGA ATAAAAGT
18021


7086
UUAUACAA A CCAAGAAU
8275
ATTCTTGG GGCTAGCTACAACGA TTGTATAA
18022


7093
AACCAAGA A UAUAUGCU
8276
AGCATATA GGCTAGCTACAACGA TCTTGGTT
18023


7095
CCAAGAAU A UAUGCUAC
1231
GTAGCATA GGCTAGCTACAACGA ATTCTTGG
18024


7097
AAGAAUAU A UGCUACAG
1232
CTGTAGCA GGCTAGCTACAACGA ATATTCTT
18025


7099
GAAUAUAU G CUACAGAU
8277
ATCTGTAG GGCTAGCTACAACGA ATATATTC
18026


7102
UAUAUGCU A CAGAUAUA
1233
TATATCTG GGCTAGCTACAACGA AGCATATA
18027


7106
UGCUACAG A UAUAAGAC
8278
GTCTTATA GGCTAGCTACAACGA CTGTAGCA
18028


7108
CUACAGAD A UAAGACAG
1234
CTGTCTTA GGCTAGCTACAACGA ATCTGTAG
18029


7113
GAUAUAAG A CAGACAUG
8279
CATGTCTG GGCTAGCTACAACGA CTTATATC
18030


7117
UAAGACAG A CAUGGUUU
8280
AAACCATG GGCTAGCTACAACGA CTGTCTTA
18031


7119
AGACAGAC A UGGUUUGG
5552
CCAAACCA GGCTAGCTACAACGA GTCTGTCT
18032


7122
CAGACAUG G UUUGGUCC
8281
GGACCAAA GGCTAGCTACAACGA CATGTCTG
18033


7127
AUGGUUUG G UCCUAUAU
8282
ATATAGGA GGCTAGCTACAACGA CAAACCAT
18034


7132
UUGGUCCU A UAUUUCUA
1239
TAGAAATA GGCTAGCTACAACGA AGGACCAA
18035


7134
GGUCCUAU A UUUCUAGU
1240
ACTAGAAA GGCTAGCTACAACGA ATAGGACC
18036


7141
UAUUUCUA G UCAUGAUG
8283
CATCATGA GGCTAGCTACAACGA TAGAAATA
18037


7144
UUCUAGUC A UGAUGAAU
5556
ATTCATCA GGCTAGCTACAACGA GACTAGAA
18038


7147
UAGUCAUG A UGAAUGUA
8284
TACATTCA GGCTAGCTACAACGA CATGACTA
18039


7151
CAUGAUGA A UGUAUUUU
8285
AAAATACA GGCTAGCTACAACGA TCATCATG
18040


7153
UGAUGAAU G UAUUUUGU
8286
ACAAAATA GGCTAGCTACAACGA ATTCATCA
18041


7155
AUGAAUGU A UUUUGUAU
1246
ATACAAAA GGCTAGCTACAACGA ACATTCAT
18042


7160
UGUAUUUU G UAUACCAU
8287
ATGGTATA GGCTAGCTACAACGA AAAATACA
18043


7162
UAUUUUGU A UACCAUCU
1250
AGATGGTA GGCTAGCTACAACGA ACAAAATA
18044


7164
UUUUGUAU A CCAUCUUC
1251
GAAGATGG GGCTAGCTACAACGA ATACAAAA
18045


7167
UGUAUACC A UCUUCAUA
5558
TATGAAGA GGCTAGCTACAACGA GGTATACA
18046


7173
CCAUCUUC A UAUAAUAU
5560
ATATTATA GGCTAGCTACAACGA GAAGATGG
18047


7175
AUCUUCAU A UAAUAUAC
1255
GTATATTA GGCTAGCTACAACGA ATGAAGAT
18048


7178
UUCAUAUA A UAUACUUA
8288
TAAGTATA GGCTAGCTACAACGA TATATGAA
18049


7180
CAUAUAAU A UACUUAAA
1257
TTTAAGTA GGCTAGCTACAACGA ATTATATG
18050


7182
UAUAAUAU A CUUAAAAA
1258
TTTTTAAG GGCTAGCTACAACGA ATATTATA
18051


7190
ACUUAAAA A UAUUUCUU
8289
AAGAAATA GGCTAGCTACAACGA TTTTAAGT
18052


7192
UUAAAAAU A UUUCUUAA
126
UTAAGAAA GGCTAGCTACAACGA ATTTTTAA
18053


7200
AUUUCUUA A UUGGGAUU
8290
AATCCCAA GGCTAGCTACAACGA TAAGAAAT
18054


7206
UAAUUGGG A UUUGUAAU
8291
ATTACAAA GGCTAGCTACAACGA CCCAATTA
18055


7210
UGGGAUUU G UAAUCGUA
8292
TAGGATTA GGCTAGCTACAACGA AAATCCCA
18056


7213
GAUUUGUA A UCGUACCA
8293
TGGTACGA GGCTAGCTACAACGA TACAAATC
18057


7216
UUGUAAUC G UACCAACU
8294
AGTTGGTA GGCTAGCTACAACGA GATTACAA
18058


7218
GUAAUCGU A CCAACUUA
1272
TAAGTTGG GGCTAGCTACAACGA ACGATTAC
18059


7222
UCGUACCA A CUUAAUUG
8295
CAATTAAG GGCTAGCTACAACGA TGGTACGA
18060


7227
CCAACUUA A UUGAUAUA
8296
TTTATCAA GGCTAGCTACAACGA TAAGTTGG
18061


7231
CUUAAUUG A UAAACUUG
8297
CAAGTTTA GGCTAGCTACAACGA CAATTAAG
18062


7235
AUUGAUAA A CUUGGCAA
8298
TTGCCAAG GGCTAGCTACAACGA TTATCAAT
18063


7240
UAAACUUG G CAACUGCU
8299
AGCAGTTG GGCTAGCTACAACGA CAAGTTTA
18064


7243
ACUUGGCA A CUGCUUUU
8300
AAAAGCAG GGCTAGCTACAACGA TGCCAAGT
18065


7246
UGGCAACU G CUUUUAUG
8301
CATAAAAG GGCTAGCTACAACGA AGTTGCCA
18066


7252
CUGCUUUU A UGUUCUGU
1281
ACAGAACA GGCTAGCTACAACGA AAAAGCAG
18067


7254
GCUUUUAU G UUCUGUCU
8302
AGACAGAA GGCTAGCTACAACGA ATAAAAGC
18068


7259
UAUGUUCU G UCUCCUUC
8303
GAAGGAGA GGCTAGCTACAACGA AGAACATA
18069


7269
CUCCUUCC A UAAAUUUU
5575
AAAATTTA GGCTAGCTACAACGA GGAAGGAG
18070


7273
UUCCAUAA A UUUUUCAA
8304
TTGAAAAA GGCTAGCTACAACGA TTATGGAA
18071


7283
UUUUCAAA A UACUAAUU
8305
AATTAGTA GGCTAGCTACAACGA TTTGAAAA
18072


7285
UUCAAAAU A CUAAUUCA
1294
TGAATTAG GGCTAGCTACAACGA ATTTTGAA
18073


7289
AAAUACUA A UUCAACAA
8306
TTGTTGAA GGCTAGCTACAACGA TAGTATTT
18074


7294
CUAAUUCA A CAAAGAAA
8307
TTTCTTTG GGCTAGCTACAACGA TGAATTAG
18075


7305
AAGAAAAA G CUCUUUUU
8308
AAAAAGAG GGCTAGCTACAACGA TTTTTCTT
18076


7323
UUCCUAAA A UAAACUCA
8309
TGAGTTTA GGCTAGCTACAACGA TTTAGGAA
18077


7327
UAAAAUAA A CUCAAAUU
8310
AATTTGAG GGCTAGCTACAACGA TTATTTTA
18078


7333
AAACUCAA A UUUAUCCU
8311
AGGATAAA GGCTAGCTACAACGA TTGAGTTT
18079


7337
UCAAAUUU A UCCUUGUU
1312
AACAAGGA GGCTAGCTACAACGA AAATTTGA
18080


7343
UUAUCCUU G UUUAGAGC
8312
GCTCTAAA GGCTAGCTACAACGA AAGGATAA
18081


7350
UGUUUAGA G CAGAGAAA
8313
TTTCTCTG GGCTAGCTACAACGA TCTAAACA
18082


7360
AGAGAAAA A UUAAGAAA
8314
TTTCTTAA GGCTAGCTACAACGA TTTTCTCT
18083


7370
UAAGAAAA A CUUUGAAA
8315
TTTCAAAG GGCTAGCTACAACGA TTTTCTTA
18084


7378
ACUUUGAA A UGGUCUCA
8316
TGAGACCA GGCTAGCTACAACGA TTCAAAGT
18085


7381
UUGAAAUG G UCUCAAAA
8317
TTTTGAGA GGCTAGCTACAACGA CATTTCAA
18086


7391
CUCAAAAA A UUGCUAAA
8318
TTTAGCAA GGCTAGCTACAACGA TTTTTGAG
18087


7394
AAAAAAUU G CUAAAUAU
8319
ATATTTAG GGCTAGCTACAACGA AATTTTTT
18088


7399
AUUGCUAA A UAUUUUCA
8320
TGAAAATA GGCTAGCTACAACGA TTAGCAAT
18089


7401
UGCUAAAU A UUUUCAAU
1326
ATTGAAAA GGCTAGCTACAACGA ATTTAGCA
18090


7408
UAUUUUCA A UGGAAAAC
8321
GTTTTCCA GGCTAGCTACAACGA TGAAAATA
18091


7415
AAUGGAAA A CUAAAUGU
8322
ACATTTAG GGCTAGCTACAACGA TTTCCATT
18092


7420
AAAACUAA A UGUUAGUU
8323
AACTAACA GGCTAGCTACAACGA TTAGTTTT
18093


7422
AACUAAAU G UUAGUUUA
8324
TAAACTAA GGCTAGCTACAACGA ATTTAGTT
18094


7426
AAAUGUUA G UUUAGCUG
8325
CAGCTAAA GGCTAGCTACAACGA TAACATTT
18095


7431
UUAGUUUA G CUGAUUGU
8326
ACAATCAG GGCTAGCTACAACGA TAAACTAA
18096


7435
UUUAGCUG A UUGUAUGG
8327
CCATACAA GGCTAGCTACAACGA CAGCTAAA
18097


7438
AGCUGAUU G UAUGGGGU
8328
ACCCCATA GGCTAGCTACAACGA AATCAGCT
18098


7440
CUGAUUGU A UGGGGUUU
1338
AAACCCCA GGCTAGCTACAACGA ACAATCAG
18099


7445
UGUAUGGG G UUUUCGAA
8329
TTCGAAAA GGCTAGCTACAACGA CCCATACA
18100


7453
GUUUUCGA A CCUUUCAC
8330
GTGAAAGG GGCTAGCTACAACGA TCGAAAAC
18101


7460
AACCUUUC A CUUUUUGU
5598
ACAAAAAG GGCTAGCTACAACGA GAAAGGTT
18102


7467
CACUUUUU G UUUGUUUU
8331
AAAACAAA GGCTAGCTACAACGA AAAAAGTG
18103


7471
UUUUGUUU G UUUUACCU
8332
AGGTAAAA GGCTAGCTACAACGA AAACAAAA
18104


7476
UUUGUUUU A CCUAUUUC
1355
GAAATAGG GGCTAGCTACAACGA AAAACAAA
18105


7480
UUUUACCU A UUUCACAA
1356
TTGTGAAA GGCTAGCTACAACGA AGGTAAAA
18106


7485
CCUAUUUC A CAACUGUG
5602
CACAGTTG GGCTAGCTACAACGA GAAATAGG
18107


7488
AUUUCACA A CUGUGUAA
8333
TTACACAG GGCTAGCTACAACGA TGTGAAAT
18108


7491
UCACAACU G UGUAAAUU
8334
AATTTACA GGCTAGCTACAACGA AGTTGTGA
18109


7493
ACAACUGU G UAAAUUGC
8335
GCAATTTA GGCTAGCTACAACGA ACAGTTGT
18110


7497
CUGUGUAA A UUGCCAAU
8336
ATTGGCAA GGCTAGCTACAACGA TTACACAG
18111


7500
UGUAAAUU G CCAAUAAU
8337
ATTATTGG GGCTAGCTACAACGA AATTTACA
18112


7504
AAUUGCCA A UAAUUCCU
8338
AGGAATTA GGCTAGCTACAACGA TGGCAATT
18113


7507
UGCCAAUA A UUCCUGUC
8339
GACAGGAA GGCTAGCTACAACGA TATTGGCA
18114


7513
UAAUUCCU G UCCAUGAA
8340
TTCATGGA GGCTAGCTACAACGA AGGAATTA
18115


7517
UCCUGUCC A UGAAAAUG
5610
CATTTTCA GGCTAGCTACAACGA GGACAGGA
18116


7523
CCAUGAAA A UGCAAAUU
8341
AATTTGCA GGCTAGCTACAACGA TTTCATGG
18117


7525
AUGAAAAU G CAAAUUAU
8342
ATAATTTG GGCTAGCTACAACGA ATTTTCAT
18118


7529
AAAUGCAA A UUAUCCAG
8343
CTGGATAA GGCTAGCTACAACGA TTGCATTT
18119


7532
UGCAAAUU A UCCAGUGU
1367
ACACTGGA GGCTAGCTACAACGA AATTTGCA
18120


7537
AUUAUCCA G UGUAGAUA
8344
TATCTACA GGCTAGCTACAACGA TGGATAAT
18121


7539
UAUCCAGU G UAGAUAUA
8345
TATATCTA GGCTAGCTACAACGA ACTGGATA
18122


7543
CAGUGUAG A UAUAUUUG
8346
CAAATATA GGCTAGCTACAACGA CTACACTG
18123


7545
GUGUAGAU A UAUUUGAC
1370
GTCAAATA GGCTAGCTACAACGA ATCTACAC
18124


7547
GUAGAUAU A UUUGACCA
137
UGGTCAAA GGCTAGCTACAACGA ATATCTAC
18125


7552
UAUAUUUG A CCAUCACC
8347
GGTGATGG GGCTAGCTACAACGA CAAATATA
18126


7555
AUUUGACC A UCACCCUA
5615
TAGGGTGA GGCTAGCTACAACGA GGTCAAAT
18127


7558
UGACCAUC A CCCUAUGG
5616
CCATAGGG GGCTAGCTACAACGA GATGGTCA
18128


7563
AUCACCCU A UGGAUAUU
1375
AATATCCA GGCTAGCTACAACGA AGGGTGAT
18129


7567
CCCUAUGG A UAUUGGCU
8348
AGCCAATA GGCTAGCTACAACGA CCATAGGG
18130


7569
CUAUGGAU A UUGGCUAG
1376
CTAGCCAA GGCTAGCTACAACGA ATCCATAG
18131


7573
GGAUAUUG G CUAGUUUU
8349
AAAACTAG GGCTAGCTACAACGA CAATATCC
18132


7577
AUUGGCUA G UUUUGCCU
8350
AGGCAAAA GGCTAGCTACAACGA TAGCCAAT
18133


7582
CUAGUUUU G CCUUUAUU
8351
AATAAAGG GGCTAGCTACAACGA AAAACTAG
18134


7588
UUGCCUUU A UUAAGCAA
1384
TTGCTTAA GGCTAGCTACAACGA AAAGGCAA
18135


7593
UUUAUUAA G CAAAUUCA
8352
TGAATTTG GGCTAGCTACAACGA TTAATAAA
18136


7597
UUAAGCAA A UUCAUUUC
8353
GAAATGAA GGCTAGCTACAACGA TTGCTTAA
18137


7601
GCAAAUUC A UUUCAGCC
5624
GGCTGAUA GGCTAGCTACAACGA GAATTTGC
18138


7607
UCAUUUCA G CCUGAAUG
8354
CATTCAGG GGCTAGCTACAACGA TGAAATGA
18139


7613
CAGGCUGA A UGUCUGCC
8355
GGCAGACA GGCTAGCTACAACGA TCAGGCTG
18140


7615
GCCUGAAU G UCUGCCUA
8356
TAGGGAGA GGCTAGCTACAACGA ATTCAGGC
18141


7619
GAAUGUCU G CCUAUAUA
8357
TATATAGG GGCTAGCTACAACGA AGACATTC
18142


7623
GUCUGCCU A UAUAUUCU
1393
AGAATATA GGCTAGCTACAACGA AGGCAGAC
18143


7625
CUGCCUAU A UAUUCUCU
1394
AGAGAATA GGCTAGCTACAACGA ATAGGCAG
18144


7627
GCCUAUAU A UUCUCUGC
1395
GCAGAGAA GGCTAGCTACAACGA ATATAGGC
18145


7634
UAUUCUCU G CUCUUUGU
8358
ACAAAGAG GGCTAGCTACAACGA AGAGAATA
18146


7641
UGCUCUUU G UAUUCUCC
8359
GGAGAATA GGCTAGCTACAACGA AAAGAGCA
18147


7643
CUCUUUGU A UUCUCCUU
1402
AAGGAGAA GGCTAGCTACAACGA ACAAAGAG
18148


7655
UCCUUUGA A CCCGUUAA
8360
TTAACGGG GGCTAGCTACAACGA TCAAAGGA
18149


7659
UUGAACCC G UUAAAACA
836
UGTTTTAA GGCTAGCTACAACGA GGGTTCAA
18150


7665
CCGUUAAA A CAUCCUGU
8362
ACAGGATG GGCTAGCTACAACGA TTTAACGG
18151


7667
GUUAAAAC A UCCUGUGG
5640
CCACAGGA GGCTAGCTACAACGA GTTTTAAC
18152


7672
AACAUCCU G UGGCACUC
8363
GAGTGCCA GGCTAGCTACAACGA AGGATGTT
18153






Input Sequence = HSFLT.




Cut Gite = R/Y




Arm Length = 8.




Core Sequence = GGCTAGCTACAACGA




HSFLT (Human flt mRNA for receptor-related tyrosine kinase.; Acc# X51602; 7680 bp)








[0358]

22





TABLE XIX










Human FLT Zinzyme and Substrate Sequence













Seq ID

Seq ID


Pos
Substrate
No
Zinzyme
No














17
UCCUCUCG G CUCCUCCC
7143
GGGAGGAG GCCGAAAGGCGAGUGAGGUCU CGAGAGGA
18154





28
CCUCCCCG G CAGCGGCG
7144
CGCCGCUG GCCGAAAGGCGAGUGAGGUCU CGGGGAGG
18155





31
CCCCGGCA G CGGCGGCG
7145
CGCCGCCG GCCGAAAGGCGAGUGAGGUCU UGCCGGGG
18156





34
CGGCAGCG G CGGCGGCU
7146
AGCCGCCG GCCGAAAGGCGAGUGAGGUCU CGCUGCCG
18157





37
CAGCGGCG G CGGCUCGG
7147
CCGAGCCG GCCGAAAGGCGAGUGAGGUCU CGCCGCUG
18158





40
CGGCGGCG G CUCGGAGC
7148
GCUCCGAG GCCGAAAGGCGAGUGAGGUCU CGCCGCCG
18159





47
GGCUCGGA G CGGGCUCC
7149
GGAGCCCG GCCGAAAGGCGAGUGAGGUCU UCCGAGCC
18160





51
CGGAGCGG G CUCCGGGG
7150
CCCCGGAG GCCGAAAGGCGAGUGAGGUCU CCGCUCCG
18161





59
GCUCCGGG G CUCGGGUG
7151
CACCCGAG GCCGAAAGGCGAGUGAGGUCU CCCGGAGC
18162





65
GGGCUCGG G UGCAGCGG
7152
CCGCUGCA GCCGAAAGGCGAGUGAGGUCU CCGAGCCC
18163





67
GCUCGGGU G CAGCGGCC
7153
GGCCGCUG GCCGAAAGGCGAGUGAGGUCU ACCCGAGC
18164





70
CGGGUGCA G CGGCCAGC
7154
GCUGGCCG GCCGAAAGGCGAGUGAGGUCU UGCACCCG
18165





73
GUGCAGCG G CCAGCGGG
7155
CCCGCUGG GCCGAAAGGCGAGUGAGGUCU CGCUGCAC
18166





77
AGCGGCCA G CGGGCCUG
7156
CAGGCCCG GCCGAAAGGCGAGUGAGGUCU UGGCCGCU
18167





81
GCCAGCGG G CCUGGCGG
7157
CCGCCAGG GCCGAAAGGCGAGUGAGGUCU CCGCUGGC
18168





86
CGGGCCUG G CGGCGAGG
7158
CCUCGCCG GCCGAAAGGCGAGUGAGGUCU CAGGCCCG
18169





89
GCCUGGCG G CGAGGAUU
7159
AAUCCUCG GCCGAAAGGCGAGUGAGGUCU CGCCAGGC
18170





108
CCGGGGAA G UGGUUGUC
7161
CACAACCA GCCGAAAGGCGAGUGAGGUCU UUCCCCGG
18171





111
GGGAAGUG G UUGUCUCC
7162
GGAGACAA GCCGAAAGGCGAGUGAGGUCU CACUUCCC
18172





114
AAGUGGUU G UCUCCUGG
7163
CCAGGAGA GCCGAAAGGCGAGUGAGGUCU AACCACUU
18173





122
GUCUCCUG G CUGGAGCC
7164
GGCUCCAG GCCGAAAGGCGAGUGAGGUCU CAGGAGAC
18174





128
UGGCUGGA G CCGCGAGA
7165
UCUCGCGG GCCGAAAGGCGAGUGAGGUCU UCCAGCCA
18175





131
CUGGAGCC G CGAGACGG
7166
CCGUCUCG GCCGAAAGGCGAGUGAGGUCU GGCUCCAG
18176





140
CGAGACGG G CGCUCAGG
7168
CCUGAGCG GCCGAAAGGCGAGUGAGGUCU CCGUCUCG
18177





142
AGACGGGC G CUCAGGGC
7169
GCCCUGAG GCCGAAAGGCGAGUGAGGUCU GCCCGUCU
18178





149
CGCUCAGG G CGCGGGGC
7170
GCCCCGCG GCCGAAAGGCGAGUGAGGUCU CCUGAGCG
18179





151
CUCAGGGC G CGGGGCCG
7171
CGGCCCCG GCCGAAAGGCGAGUGAGGUCU GCCCUGAG
18180





156
GGCGCGGG G CCGGCGGC
7172
GCCGCCGG GCCGAAAGGCGAGUGAGGUCU CCCGCGCC
18181





160
CGGGGCCG G CGGCGGCG
7173
CGCCGCCG GCCGAAAGGCGAGUGAGGUCU CGGCCCCG
18182





163
GGCCGGCG G CGGCGAAC
7174
GUUCGCCG GCCGAAAGGCGAGUGAGGUCU CGCCGGCC
18183





166
CGGCGGCG G CGAACGAG
7175
CUCGUUCG GCCGAAAGGCGAGUGAGGUCU CGCCGGCC
18184





188
GCAGUCUG G CGGCCGGG
7179
CCCGGCCG GCCGAAAGGCGAGUGAGGUCU CAGAGUCC
18185





191
CUCUGGCG G CCGGGUCG
7180
CGACCCGG GCCGAAAGGCGAGUGAGGUCU CGCCAGAG
18186





196
GCGGCCGG G UCGUUGGC
7181
GCCAACGA GCCGAAAGGCGAGUGAGGUCU CCGGCCGC
18187





199
GCCGGGUC G UUGGCCGG
7182
CCGGCCAA GCCGAAAGGCGAGUGAGGUCU GACCCGGC
18188





203
GGUCGUUG G CCGGGGGA
7183
UCCCCCGG GCCGAAAGGCGAGUGAGGUCU CAACGACC
18189





212
CCGGGGGA G CGCGGGCA
7184
UGCCCGCG GCCGAAAGGCGAGUGAGGUCU UCCCCCGG
18190





214
GGGGGAGC G CGGGCACC
7185
GGUGCCCG GCCGAAAGGCGAGUGAGGUCU GCUCCCCC
18191





218
GAGCGCGG G CACCGGGC
7186
GCCCGGUG GCCGAAAGGCGAGUGAGGUCU CCGCGCUC
18192





225
GGCACCGG G CGAGCAGG
7187
CCUGCUCG GCCGAAAGGCGAGUGAGGUCU CCGGUGCC
18193





229
CCGGGCGA G CAGGCCGC
7188
GCGGCCUG GCCGAAAGGCGAGUGAGGUCU UCGCCCGG
18194





233
GCGAGCAG G CCGCGUCG
7189
CGACGCGG GCCGAAAGGCGAGUGAGGUCU CUGCUCGC
18195





236
AGCAGGCC G CGUCGCGC
7190
GCGCGACG GCCGAAAGGCGAGUGAGGUCU GGCCUGCU
18196





238
CAGGCCGC G UCGCGCUC
7191
GAGCGCGA GCCGAAAGGCGAGUGAGGUCU GCGGCCUG
18197





241
GCCGCGUC G CGCUCACC
7192
GGUGAGCG GCCGAAAGGCGAGUGAGGUCU GACGCGGC
18198





243
CGCGUCGC G CUCACCAU
7193
AUGGUGAG GCCGAAAGGCGAGUGAGGUCU GCGACGCG
18199





253
UCACCAUG G UCAGCUAC
7194
GUAGCUGA GCCGAAAGGCGAGUGAGGUCU CAUGGUGA
18200





257
CAUGGUCA G CUACUGGG
7195
CCCAGUAG GCCGAAAGGCGAGUGAGGUCU UGACCAUG
18201





274
ACACCGGG G UCCUGCUG
7197
CAGCAGGA GCCGAAAGGCGAGUGAGGUCU CCCGGUGU
18202





279
GGGGUCCU G CUGUGCGC
7198
GCGCACAG GCCGAAAGGCGAGUGAGGUCU AGGACCCC
18203





282
GUCCUGCU G UGCGCGCU
7199
AGCGCGCA GCCGAAAGGCGAGUGAGGUCU AGCAGGAC
18204





284
CCUGCUGU G CGCGCUGC
7200
GCAGCGCG GCCGAAAGGCGAGUGAGGUCU ACAGCAGG
18205





286
UGCUGUGC G CGCUGCUC
7201
GAGCAGCG GCCGAAAGGCGAGUGAGGUCU GCACAGCA
18206





288
CUGUGCGC G CUGCUCAG
7202
CUGAGCAG GCCGAAAGGCGAGUGAGGUCU GCGCACAG
18207





291
UGCGCGCU G CUCAGCUG
7203
CAGCUGAG GCCGAAAGGCGAGUGAGGUCU AGCGCGCA
18208





296
GCUGCUCA G CUGUCUGC
7204
GCAGACAG GCCGAAAGGCGAGUGAGGUCU UGAGCAGC
18209





299
GCUCAGCU G UCUGCUUC
7205
GAAGCAGA GCCGAAAGGCGAGUGAGGUCU AGCUGAGC
18210





303
AGCUGUCU G CUUCUCAC
7206
GUGAGAAG GCCGAAAGGCGAGUGAGGUCU AGACAGCU
18211





320
AGGAUCUA G UUCAGGUU
7208
AACCUGAA GCCGAAAGGCGAGUGAGGUCU UAGAUCCU
18212





326
UAGUUCAG G UUCAAAAU
7209
AUUUUGAA GCCGAAAGGCGACUGAGGUCU CUGAACUA
18213





353
UGAACUGA G UUUAAAAG
7213
CUUUUAAA GCCGAAAGGCGAGUGAGGUCU UCAGUUCA
18214





362
UUUAAAAG G CACCCAGC
7214
GCUGGGUG GCCGAAAGGCGAGUGAGGUCU CUUUUAAA
18215





369
GGCACCCA G CACAUCAU
7215
AUGAUGUG GCCGAAAGGCGAGUGAGGUCU UGGGUGCC
18216





378
CACAUCAU G CAAGCAGG
7216
CCUGCUUG GCCGAAAGGCGAGUGAGGUCU AUGAUGUG
18217





382
UCAUGCAA G CAGGCCAG
7217
CUGGCCUG GCCGAAAGGCGAGUGAGGUCU UUGCAUGA
18218





386
GCAAGCAG G CCAGACAC
7218
GUGUCUGG GCCGAAAGGCGAGUGAGGUCU CUGCUUGC
18219





396
CAGACACU G CAUCUCCA
7220
UGGAGAUG GCCGAAAGGCGACUGAGGUCU AGUGUCUG
18220





407
UCUCCAAU G CAGGGGGG
7222
CCCCCCUG GCCGAAAGGCGAGUGAGGUCU AUUGGAGA
18221





418
GGGGGGAA G CAGCCCAU
7223
AUGGGCUG GCCGAAAGGCGAGUGAGGUCU UUCCCCCC
18222





421
GGGAAGCA G CCCAUAAA
7224
UUUAUGGG GCCGAAAGGCGAGUGAGGUCU UGCUUCCC
18223





432
CAUAAAUG G UCUUUGCC
7226
GGCAAAGA GCCGAAAGGCGAGUGAGGUCU CAUUUAUG
18224





438
UGGUCUUU G CCUGAAAU
7227
AUUUCAGG GCCGAAAGGCGAGUGAGGUCU AAAGACCA
18225





448
CUGAAAUG G UGAGUAAG
7229
CUUACUCA GCCGAAAGGCGAGUGAGGUCU CAUUUCAG
18226





452
AAUGGUGA G UAAGGAAA
7230
UUUCCUUA GCCGAAAGGCGAGUGAGGUCU UCACCAUU
18227





461
UAAGGAAA G CGAAAGGC
7231
GCCUUUCG GCCGAAAGGCGACUGAGGUCU UUUCCUUA
18228





468
AGCGAAAG G CUGAGCAU
7232
AUGCUCAG GCCGAAAGGCGAGUGAGGUCU CUUUCGCU
18229





473
AAGGCUGA G CAUAACUA
7233
UAGUUAUG GCCGAAAGGCGAGUGAGGUCU UCAGCCUU
18230





487
CUAAAUCU G CCUGUGGA
7236
UCCACAGG GCCGAAAGGCGAGUGAGGUCU AGAUUUAG
18231





491
AUCUGCCU G UGGAAGAA
7237
UUCUUCCA GCCGAAAGGCGAGUGAGGUCU AGGCAGAU
18232





503
AAGAAAUG G CAAACAAU
7239
AUUGUUUG GCCGAAAGGCGAGUGAGGUCU CAUUUCUU
18233





515
ACAAUUCU G CAGUACUU
7242
AAGUACUG GCCGAAAGGCGAGUGAGGUCU AGAAUUGU
18234





518
AUUCUGCA G UACUUUAA
7243
UUAAAGUA GCCGAAAGGCGAGUGAGGUCU UGCAGAAU
18235





538
UGAACACA G CUCAAGCA
7246
UGCUUGAG GCCGAAAGGCGAGUGAGGUCU UGUGUUCA
18236





544
CAGCUCAA G CAAACCAC
7247
GUGGUUUG GCCGAAAGGCGAGUGAGGUCU UUGAGCUG
18237





557
CCACACUG G CUUCUACA
7249
UGUAGAAG GCCGAAAGGCGAGUGAGGUCU CAGUGUGG
18238





566
CUUCUACA G CUGCAAAU
7250
AUUUGCAG GCCGAAAGGCGAGUGAGGUCU UGUAGAAG
18239





569
CUACAGCU G CAAAUAUC
7251
GAUAUUUG GCCGAAAGGCGAGUGAGGUCU AGCUGUAG
18240





580
AAUAUCUA G CUGUACCU
7253
AGGUACAG GCCGAAAGGCGAGUGAGGUCU UAGAUAUU
18241





583
AUCUAGCU G UACCUACU
7254
AGUAGGUA GCCGAAAGGCGAGUGAGGUCU AGCUAGAU
18242





616
CAGAAUCU G CAAUCUAU
7257
AUAGAUUG GCCGAAAGGCGAGUGAGGUCU AGAUUCUG
18243





635
AUUUAUUA G UGAUACAG
7259
CUGUAUCA GCCGAAAGGCGAGUGAGGUCU UAAUAAAU
18244





644
UGAUACAG G UAGACCUU
7261
AAGGUCUA GCCGAAAGGCGAGUGAGGUCU CUGUAUCA
18245





855
GACCUUUC G UAGAGAUG
7263
CAUCUCUA GCCGAAAGGCGAGUGAGGUCU GAAAGGUC
18246





663
GUAGAGAU G UACAGUGA
7265
UCACUGUA GCCGAAAGGCGAGUGAGGUCU AUCUCUAC
18247





668
GAUGUACA G UGAAAUCC
7266
GGAUUUCA GCCGAAAGGCGAGUGAGGUCU UGUACAUC
18248





708
GGAAGGGA G CUCGUCAU
7270
AUGACGAG GCCGAAAGGCGAGUGAGGUCU UCCCUUCC
18249





712
GGGAGCUC G UCAUUCCC
7271
GGGAAUGA GCCGAAAGGCGAGUGAGGUCU GAGCUCCC
18250





722
CAUUCCCU G CCGGGUUA
7272
UAACCCGG GCCGAAAGGCGAGUGAGGUCU AGGGAAUG
18251





727
CCUGCCGG G UUACGUCA
7273
UGACGUAA GCCGAAAGGCGAGUGAGGUCU CCGGCAGG
18252





732
CGGGUUAC G UCACCUAA
7274
UUAGGUGA GCCGAAAGGCGAGUGAGGUCU GUAACCCG
18253





748
ACAUCACU G UUACUUUA
7276
UAAAGUAA GCCGAAAGGCGAGUGAGGUCU AGUGAUGU
18254





762
UUAAAAAA G UUUCCACU
7277
AGUGGAAA GCCGAAAGGCGAGUGAGGUCU UUUUUUAA
18255





797
UGGAAAAC G CAUAAUCU
7282
AGAUUAUG GCCGAAAGGCGAGUGAGGUCU GUUUUCCA
18256





812
CUGGGACA G UAGAAAGG
7285
CCUUUCUA GCCGAAAGGCGAGUGAGGUCU UGUCCCAG
18257





821
UAGAAAGG G CUUCAUCA
7286
UGAUGAAG GCCGAAAGGCGAGUGAGGUCU CCUUUCUA
18258





838
UAUCAAAU G CAACGUAC
7288
GUACGUUG GCCGAAAGGCGAGUGAGGUCU AUUUGAUA
18259





843
AAUGCAAC G UACAAAGA
7290
UCUUUGUA GCCGAAAGGCGAGUGAGGUCU GUUGCAUU
18260





858
GAAAUAGG G CUUCUGAC
7292
GUCAGAAG GCCGAAAGCCGAGUGAGGUCU CCUAUUUC
18261





869
UCUGACCU G UGAAGCAA
7294
UUGCUUCA GCCGAAAGGCGACUGAGGUCU AGGUCAGA
18262





874
CCUGUGAA G CAACAGUC
7295
GACUGUUG GCCGAAAGGCGAGUGAGGUCU UUCACAGG
18263





880
AAGCAACA G UCAAUGGG
7297
CCCAUUGA GCCGAAAGGCGAGUGAGGUCU UGUUGCUU
18264





888
GUCAAUGG G CAUUUGUA
7299
UACAAAUG GCCGAAAGGCGAGUGAGGUCU CCAUUGAC
18265





894
GGGCAUUU G UAUAAGAC
7300
GUCUUAUA GCCGAAAGGCGAGUGAGGUCU AAAUGCCC
18266





943
UCAUAGAU G UCCAAAUA
7308
UAUUUGGA GCCGAAAGGCGAGUGAGGUCU AUCUAUGA
18267





953
CCAAAUAA G CACACCAC
7310
GUGGUGUG GCCGAAAGGCGAGUGAGGUCU UUAUUUGG
18268





962
CACACCAC G CCCAGUCA
7311
UGACUGGG GCCGAAAGGCGAGUGAGGUCU GUGGUGUG
18269





967
CACGCCCA G UCAAAUUA
7312
UAAUUUGA GCCGAAAGCCGACUCAGCUCU UGGGCGUG
18270





983
ACUUAGAG G CCAUACUC
7314
GAGUAUGG GCCGAAAGGCGAGUGAGGUCU CUCUAAGU
18271





994
AUACUCUU G UCCUCAAU
7315
AUUGAGGA GCCGAAAGGCGAGUGAGGUCU AAGAGUAU
18272





1004
CCUCAAUU G UACUGCUA
7317
UAGCAGUA GCCGAAAGGCGAGUGAGGUCU AAUUGAGG
18273





1009
AUUGUACU G CUACCACU
7318
AGUGGUAG GCCGAAAGGCGAGUGAGGUCU AGUACAAU
18274





1033
ACACGAGA G UUCAAAUG
7320
CAUUUGAA GCCGAAAGGCGAGUGAGGUCU UCUCGUGU
18275





1049
GACCUGGA G UUACCCUG
7323
CAGGGUAA GCCGAAAGGCGAGUGAGGUCU UCCAGGUC
18276





1075
AUAAGAGA G CUUCCGUA
7326
UACGGAAG GCCGAAAGGCGAGUGAGGUCU UCUCUUAU
18277





1081
GAGCUUCC G UAAGGCGA
7327
UCGCCUUA GCCGAAAGGCGAGUGAGGUCU GGAAGCUC
18278





1086
UCCGUAAG G CGACGAAU
7328
AUUCGUCG GCCGAAAGGCGAGUGAGGUCU CUUACGGA
18279





1103
UGACCAAA G CAAUUCCC
7332
GGGAAUUG GCCGAAAGGCGAGUGAGGUCU UUUGGUCA
18280





1114
AUUCCCAU G CCAACAUA
7334
UAUGUUGG GCCGAAAGGCGAGUGAGGUCU AUGGGAAU
18281





1130
AUUCUACA G UGUUCUUA
7336
UAAGAACA GCCGAAAGGCGAGUGAGGUCU UGUAGAAU
18282





1132
UCUACAGU G UUCUUACU
7337
AGUAAGAA GCCGAAAGGCGAGUGAGGUCU ACUGUAGA
18283





1152
GACAAAAU G CAGAACAA
7340
UUGUUCUG GCCGAAAGGCGAGUGAGGUCU AUUUUGUC
18284





1181
UUAUACUU G UCGUGUAA
7344
UUACACGA GCCGAAAGGCGAGUGAGGUCU AAGUAUAA
18285





1184
UACUUGUC G UGUAAGGA
7345
UCCUUACA GCCGAAAGGCGAGUGAGGUCU GACAAGUA
18286





1186
CUUGUCGU G UAAGGAGU
7346
ACUCCUUA GCCGAAAGGCGAGUGAGGUCU ACGACAAG
18287





1193
UGUAAGGA G UGGACCAU
7347
AUGGUCCA GCCGAAAGGCGAGUGAGGUCU UCCUUACA
18288





1213
UCAAAUCU G UUAACACC
7350
GGUGUUAA GCCGAAAGGCGAGUGAGGUCU AGAUUUGA
18289





1225
ACACCUCA G UGCAUAUA
7352
UAUAUGCA GCCGAAAGGCGAGUGAGGUCU UGAGGUGU
18290





1227
ACCUCAGU G CAUAUAUA
7353
UAUAUAUG GCCGAAAGGCGAGUGAGGUCU ACUGAGGU
18291





1243
AUGAUAAA G CAUUCAUC
7355
GAUGAAUG GCCGAAAGGCGAGUGAGGUCU UUUAUCAU
18292





1255
UCAUCACU G UGAAACAU
7356
AUGUUUCA GCCGAAAGGCGACUGAGGUCU AGUGAUGA
18293





1272
CGAAAACA G CAGGUGCU
7359
AGCACCUG GCCGAAAGGCGAGUGAGGUCU UGUUUUCG
18294





1276
AACAGCAG G UGCUUGAA
7360
UUCAAGCA GCCGAAAGGCGAGUGAGGUCU CUGCUGUU
18295





1278
CAGCAGGU G CUUGAAAC
7361
GUUUCAAG GCCGAAAGGCGAGUGAGGUCU ACCUGCUG
18296





1288
UUGAAACC G UAGCUGGC
7363
GCCAGCUA GCCGAAAGGCGAGUGAGGUCU GGUUUCAA
18297





1291
AAACCGUA G CUGGCAAG
7364
CUUGCCAG GCCGAAAGGCGAGUGAGGUCU UACGGUUU
18298





1295
CGUAGCUG G CAAGCGGU
7365
ACCGCUUG GCCGAAAGGCGAGUGAGGUCU CAGCUACG
18299





1299
GCUGGCAA G CGGUCUUA
7366
UAAGACCG GCCGAAAGGCGAGUGAGGUCU UUGCCAGC
18300





1302
GGCAAGCG G UCUUACCG
7367
CGGUAAGA GCCGAAAGGCGAGUGAGGUCU CGCUUGCC
18301





1311
UCUUACCG G CUCUCUAU
7368
AUAGAGAG GCCGAAAGGCGAGUGAGGUCU CGGUAAGA
18302





1324
CUAUGAAA G UGAAGGCA
7369
UGCCUUCA GCCGAAAGGCGAGUGAGGUCU UUUCAUAG
18303





1330
AAGUGAAG G CAUUUCCC
7370
GGGAAAUG GCCGAAAGGCGAGUGAGGUCU CUUCACUU
18304





1341
UUUCCCUC G CCGGAAGU
7371
ACUUCCGG GCCGAAAGGCGAGUGAGGUCU GAGGGAAA
18305





1348
CGCCGGAA G UUGUAUGG
7372
CCAUACAA GCCGAAAGGCGAGUGAGGUCU UUCCGGCG
18306





1351
CGGAAGUU G UAUGGUUA
7373
UAACCAUA GCCGAAAGGCGAGUGAGGUCU AACUUCCG
18307





1356
GUUGUAUG G UUAAAAGA
7374
UCUUUUAA GCCGAAAGGCGAGUGAGGUCU CAUACAAC
18308





1368
AAAGAUGG G UUACCUGC
7376
GCAGGUAA GCCGAAAGGCGAGUGAGGUCU CCAUCUUU
18309





1375
GGUUACCU G CGACUGAG
7377
CUCAGUCG GCCGAAAGGCGAGUGAGGUCU AGGUAACC
18310





1390
AGAAAUCU G CUCGCUAU
7380
AUAGCGAG GCCGAAAGGCGAGUGAGGUCU AGAUUUCU
18311





1394
AUCUGCUC G CUAUUUGA
7381
UCAAAUAG GCCGAAAGGCGAGUGAGGUCU GAGCAGAU
18312





1406
UUUGACUC G UGGCUACU
7383
AGUAGCCA GCCGAAAGGCGAGUGAGGUCU GAGUCAAA
18313





1409
GACUCGUG G CUACUCGU
7384
ACGAGUAG GCCGAAAGGCGAGUUAGGUCU CACGAGUC
18314





1416
GGCUACUC G UUAAUUAU
7385
AUAAUUAA GCCGAAAGGCGAGUGAGGUCU GAGUAGCC
18315





1432
UCAAGGAC G UAACUGAA
7388
UUCAGUUA GCCGAAAGGCGAGUGAUGUCU GUCCUUGA
18316





1447
AAGAGGAU G CAGGGAAU
7391
AUUCCCUG GCCGAAAGGCGAGUGAGGUCU AUCCUCUU
18317





1467
ACAAUCUU G CUGAGCAU
7394
AUGCUCAG GCCGAAAGGCGAGUGAGGUCU AAGAUUGU
18318





1472
CUUGCUGA G CAUAAAAC
7395
GUUUUAUG GCCGAAAGGCGAGUGAGGUCU UCAGCAAG
18319





1482
AUAAAACA G UCAAAUGU
7397
ACAUUUGA GCCGAAAGGCGAGUGAGGUCU UGUUUUAU
18320





1489
AGUCAAAU G UGUUUAAA
7399
UUUAAACA GCCGAAAGGCGAGUGAGGUCU AUUUGACU
18321





1491
UCAAAUGU G UUUAAAAA
7400
UUUUUAAA GCCGAAAGGCGAGUGAGGUCU ACAUUUGA
18322





1507
ACCUCACU G CCACUCUA
7402
UAGAGUGG GCCGAAAGGCGAGUGAGGUCU AGUGAGGU
18323





1519
CUCUAAUU G UCAAUGUG
7404
CACAUUGA GCCGAAAGGCGAGUGAGGUCU AAUUAGAG
18324





1525
UUGUCAAU G UGAAACCC
7406
GGGUUUCA GCCGAAAGGCGAGUGAUGUCU AUUGACAA
18325





1549
ACGAAAAG G CCGUGUCA
7409
UGACACGG GCCGAAAGGCGAGUGAGGUCU CUUUUCGU
18326





1552
AAAAGGCC G UGUCAUCG
7410
CGAUGACA GCCGAAAGGCGAGUGAGGUCU GGCCUUUU
18327





1554
AAGGCCGU G UCAUCGUU
7411
AACGAUGA GCCGAAAGGCGAGUGAGGUCU ACGGCCUU
18328





1560
GUGUCAUC G UUUCCAGA
7412
UCUGGAAA GCCGAAAGGCGAGUGAGGUCU GAUGACAC
18329





1573
CAGACCCG G CUCUCUAC
7414
GUAGAGAG GCCGAAAGGCGAGUGAGGUCU CGGGUCUG
18330





1589
CCCACUGG G CAGCAGAC
7415
GUCUGCUG GCCGAAAGGCGAGUGAGGUCU CCAGUGGG
18331





1592
ACUGGGCA G CAGACAAA
7416
UUUGUCUG GCCGAAAGGCGAGUGAGGUCU UGCCCAGU
18332





1610
CCUGACUU G UACCGCAU
7420
AUGCGGUA GCCGAAAGGCGAGUGAGGUCU AAGUCAGG
18333





1615
CUUGUACC G CAUAUGGU
7421
ACCAUAUG GCCGAAAGGCGAGUGAGGUCU GGUACAAG
18334





1622
CGCAUAUU G UAUCCCUC
7422
GAGGGAUA GCCGAAAGGCGAGUGAGGUCU CAUAUGCG
18335





1644
ACAAUCAA G UGGUUCUG
7425
CAGAACCA GCCGAAAGGCGAGUGAGGUCU UUGAUUGU
18336





1647
AUCAAGUG G UUCGGUCA
7426
UGCCAGAA GCCGAAAGGCGAGUGAGGUCU CACUUGAU
18337





1653
UGGUUCUG G CACCCCUG
7427
CAGGGGUG GCCGAAAGGCGAGUGAGGUCU CAGAACCA
18338





1661
GCACCCCU G UAACCAUA
7428
UAUGGUUA GCCGAAAGGCGAGUGAGGUCU AGGGGUGC
18339





1681
AUUCCGAA G CAAGGUGU
7431
ACACCUUG GCCGAAAGGCGAGUGAGGUCU UUCGGAAU
18340





1686
GAAGCAAG G UGUGACUU
7432
AAGUCACA GCCGAAAGGCGAGUGAGGUCU CUUGCUUC
18341





1688
AGCAAGGU G UGACUUUU
7433
AAAAGUCA GCCGAAAGGCGAGUGAGGUCU ACCUUGCU
18342





1697
UGACUUUU G UUCCAAUA
7435
UAUUGGAA GCCGAAAGGCGAGUGAGGUCU AAAAGUCA
18343





1713
AAUGAAGA G UCCUUUAU
7438
AUAAAGGA GCCGAAAGGCGAGUGAGGUCU UCUUCAUU
18344





1729
UCCUGGAU G CUGACAGC
7440
GCUGUCAG GCCGAAAGGCGAGUGAGGUCU AUCCAGGA
18345





1736
UGCUGACA G CAACAUGG
7442
CCAUGUUG GCCGAAAGGCGAGUGAGGUCU UGUCAGCA
18346





1760
AAUUGAGA G CAUCACUC
7446
GAGUGAUG GCCGAAAGGCGAGUGAGGUCU UCUCAAUU
18347





1770
AUCACUCA G CGCAUGGC
7447
GCCAUGCG GCCGAAAGGCGAGUGAGGUCU UGAGUGAU
18348





1772
CACUCAGC G CAUGGCAA
7448
UUGCCAUG GCCGAAAGGCGAGUGAGGUCU GCUGAGUG
18349





1777
AGCGCAUG G CAAUAAUA
7449
UAUUAUUG GCCGAAAGGCGAGUGAGGUCU CAUGCGCU
18350





1804
AUAAGAUG G CUAGCACC
7454
GGUGCUAG GCCGAAAGGCGAGUGAGGUCU CAUCUUAU
18351





1808
GAUGGCUA G CACCUUGG
7455
CCAAGGUG GCCGAAAGGCGAGUGAGGUCU UAGCCAUC
18352





1816
GCACCUUG G UUGUGGCU
7456
AGCCACAA GCCGAAAGGCGAGUGAGGUCU CAAGGUGC
18353





1819
CCUUGGUU G UGGCUGAC
7457
GUCAGCCA GCCGAAAGGCGAGUGAGGUCU AACCAAGG
18354





1822
UGGUUGUG G CUGACUCU
7458
AGAGUCAG GCCGAAAGGCGAGUGAGGUCU CACAACCA
18355





1853
CUACAUUU G CAUAGCUU
7462
AAGCUAUG GCCGAAAGGCGAGUGAGGUCU AAAUGUAG
18356





1858
UUUGCAUA G CUUCCAAU
7463
AUUGGAAG GCCGAAAGGCGAGUGAGGUCU UAUGCAAA
18357





1870
CCAAUAAA G UUGGGACU
7465
AGUCCCAA GCCGAAAGGCGAGUGAGGUCU UUUAUUGG
18358





1879
UUGGGACU G UGGGAAGA
7467
UCUUCCCA GCCGAAAGGCGAGUGAGGUCU AGUCCCAA
18359





1895
AAACAUAA G CUUUUAUA
7469
UAUAAAAG GCCGAAAGGCGAGUGAGGUCU UUAUGUUU
18360





1912
UCACAGAU G UGCCAAAU
7471
AUUUGGCA GCCGAAAGGCGAGUGAGGUCU AUCUGUGA
18361





1914
ACAGAUGU G CCAAAUGG
7472
CCAUUUGG GCCGAAAGGCGAGUGAGGUCU ACAUCUGU
18362





1923
CCAAAUGG G UUUCAUGU
7474
ACAUGAAA GCCGAAAGGCGAGUGAGGUCU CCAUUUGG
18363





1930
GGUUUCAU G UUAACUUG
7475
CAAGUUAA GCCGAAAGGCGAGUGAGGUCU AUGAAACC
18364





1947
GAAAAAAU G CCGACGGA
7478
UCCGUCGG GCCGAAAGGCGAGUGAGGUCU AUUUUUUC
18365





1974
CUGAAACU G UCUUGCAC
7482
GUGCAAGA GCCGAAAGGCGAGUGAGGUCU AGUUUCAG
18366





1979
ACUGUCUU G CACAGUUA
7483
UAACUGUG GCCGAAAGGCGAGUGAGGUCU AAGACAGU
18367





1984
CUUGCACA G UUAACAAG
7484
CUUGUUAA GCCGAAAGGCGAGUGAGGUCU UGUGCAAG
18368





1992
GUUAACAA G UUCUUAUA
7486
UAUAAGAA GCCGAAAGGCGAGUGAGGUCU UUGUUAAC
18369





2008
ACAGAGAC G UUACUUGG
7488
CCAAGUAA GCCGAAAGGCGAGUGAGGUCU GUCUCUGU
18370





2025
AUUUUACU G CGGACAGU
7490
ACUGUCCG GCCGAAAGGCGAGUGAGGUCU AGUAAAAU
18371





2032
UGCGGACA G UUAAUAAC
7492
GUUAUUAA GCCGAAAGGCGAGUGAGGUCU UGUCCGCA
18372





2049
AGAACAAU G CACUACAG
7497
CUGUAGUG GCCGAAAGGCGAGUGAGGUCU AUUGUUCU
18373





2057
GCACUACA G UAUUAGCA
7498
UGCUAAUA GCCGAAAGGCGAGUGAGGUCU UGUAGUGC
18374





2063
CAGUAUUA G CAAGCAAA
7499
UUUGCUUG GCCGAAAGGCGAGUGAGGUCU UAAUACUG
18375





2067
AUUAGCAA G CAAAAAAU
7500
AUUUUUUG GCCGAAAGGCGAGUGAGGUCU UUGCUAAU
18376





2077
AAAAAAUG G CCAUCACU
7502
AGUGAUGG GCCGAAAGGCGAGUGAGGUCU CAUUUUUU
18377





2091
ACUAAGGA G CACUCCAU
7503
AUGGAGUG GCCGAAAGGCGAGUGAGGUCU UCCUUAGU
18378





2125
UCAUGAAU G UUUCCCUG
7506
CAGGGAAA GCCGAAAGGCGAGUGAGGUCU AUUCAUGA
18379





2133
GUUUCCCU G CAAGAUUC
7507
GAAUCUUG GCCGAAAGGCGAGUGAGGUCU AGGGAAAC
18380





2144
AGAUUCAG G CACCUAUG
7509
CAUAGGUG GCCGAAAGGCGAGUGAGGUCU CUGAAUCU
18381





2152
GCACCUAU G CCUGCAGA
7510
UCUGCAGG GCCGAAAGGCGAGUGAGGUCU AUAGGUGC
18382





2156
CUAUGCCU G CAGAGCCA
7511
UGGCUCUG GCCGAAAGGCGAGUGAGGUCU AGGCAUAG
18383





2161
CCUGCAGA G CCAGGAAU
7512
AUUCCUGG GCCGAAAGGCGAGUGAGGUCU UCUGCAGG
18384





2170
CCAGGAAU G UAUACACA
7514
UGUGUAUA GCCGAAAGGCGAGUGAGGUCU AUUCCUGG
18385





2227
AUCAGGAA G CACCAUAC
7519
GUAUGGUG GCCGAAAGGCGAGUGAGGUCU UUCCUGAU
18386





2241
UACCUCCU G CGAAACCU
7520
AGGUUUCG GCCGAAAGGCGAGUGAGGUCU AGGAGGUA
18387





2252
AAACCUCA G UGAUCACA
7522
UGUGAUCA GCCGAAAGGCGAGUGAGGUCU UGAGGUUU
18388





2263
AUCACACA G UGGCCAUC
7524
GAUGGCCA GCCGAAAGGCGAGUGAGGUCU UGUGUGAU
18389





2266
ACACAGUG G CCAUCAGC
7525
GCUGAUGG GCCGAAAGGCGAGUGAGGUCU CACUGUGU
18390





2273
GGCCAUCA G CAGUUCCA
7526
UGGAACUG GCCGAAAGGCGAGUGAGGUCU UGAUGGCC
18391





2276
CAUCAGCA G UUCCACCA
7527
UGGUGGAA GCCGAAAGGCGAGUGAGGUCU UGCUGAUG
18392





2294
UUUAGACU G UCAUGCUA
7529
UAGCAUGA GCCGAAAGGCGAGUGAGGUCU AGUCUAAA
18393





2299
ACUGUCAU G CUAAUGGU
7530
ACCAUUAG GCCGAAAGGCGAGUGAGGUCU AUGACAGU
18394





2306
UGCUAAUG G UGUCCCCG
7532
CGGGGACA GCCGAAAGGCGAGUGAGGUCU CAUUAGCA
18395





2308
CUAAUGGU G UCCCCGAG
7533
CUCGGGGA GCCGAAAGGCGAGUGAGGUCU ACCAUUAG
18396





2316
GUCCCCGA G CCUCAGAU
7534
AUCUGAGG GCCGAAAGGCGAGUGAGGUCU UCGGGGAC
18397





2331
AUCACUUG G UUUAAAAA
7536
UUUUUAAA GCCGAAAGGCGAGUGAGGUCU CAAGUGAU
18398





2361
CAACAAGA G CCUGGAAU
7541
AUUCCAGG GCCGAAAGGCGAGUGAGGUCU UCUUGUUG
18399





2387
ACCAGGAA G CAGCACGC
7544
GCGUGCUG GCCGAAAGGCGAGUGAGGUCU UUCCUGGU
18400





2390
AGGAAGCA G CACGCUGU
7545
ACAGCGUG GCCGAAAGGCGAGUGAGGUCU UGCUUCCU
18401





2394
AGCAGCAC G CUGUUUAU
7546
AUAAACAG GCCGAAAGGCGAGUGAGGUCU GUGCUGCU
18402





2397
AGCACGCU G UUUAUUGA
7547
UCAAUAAA GCCGAAAGGCGAGUGAGGUCU AGCGUGCU
18403





2410
UUGAAAGA G UCACAGAA
7548
UUCUGUGA GCCGAAAGGCGAGUGAGGUCU UCUUUCAA
18404





2429
GGAUGAAG G UGUCUAUC
7550
GAUAGACA GCCGAAAGGCGAGUGAGGUCU CUUCAUCC
18405





2431
AUGAAGGU G UCUAUCAC
7551
GUGAUAGA GCCGAAAGGCGAGUGAGGUCU ACCUUCAU
18406





2441
CUAUCACU G CAAAGCCA
7552
UGGCUUUG GCCGAAAGGCGAGUGAGGUCU AGUGAUAG
18407





2446
ACUGCAAA G CCACCAAC
7553
GUUGGUGG GCCGAAAGGCGAGUGAGGUCU UUUGCAGU
18408





2462
CCAGAAGG G CUCUGUGG
7555
CCACAGAG GCCGAAAGGCGAGUGAGGUCU CCUUCUGG
18409





2467
AGGGCUCU G UGGAAAGU
7556
ACUUUCCA GCCGAAAGGCGAGUGAGGUCU AGAGCCCU
18410





2474
UGUGGAAA G UUCAGCAU
7557
AUGCUGAA GCCGAAAGGCGAGUGAGGUCU UUUCCACA
18411





2479
AAAGUUCA G CAUACCUC
7558
GAGGUAUG GCCGAAAGGCGAGUGAGGUCU UGAACUUU
18412





2491
ACCUCACU G UUCAAGGA
7559
UCCUUGAA GCCGAAAGGCGAGUGAGGUCU AGUGAGGU
18413





2511
UCGGACAA G UCUAAUCU
7562
AGAUUAGA GCCGAAAGGCGAGUGAGGUCU UUGUCCGA
18414





2523
AAUCUGGA G CUGAUCAC
7564
GUGAUCAG GCCGAAAGGCGAGUGAGGUCU UCCAGAUU
18415





2540
UCUAACAU G CACCUGUG
7567
CACAGGUG GCCGAAAGGCGAGUGAGGUCU AUGUUAGA
18416





2546
AUGCACCU G UGUGGCUG
7568
CAGCCACA GCCGAAAGGCGAGUGAGGUCU AGGUGCAU
18417





2548
GCACCUGU G UGGCUGCG
7569
CGCAGCCA GCCGAAAGGCGAGUGAGGUCU ACAGGUGC
18418





2551
CCUGUGUG G CUGCGACU
7570
AGUCGCAG GCCGAAAGGCGAGUGAGGUCU CACACAGG
18419





2554
GUGUGGCU G CGACUCUC
7571
GAGAGUCG GCCGAAAGGCGAGUGAGGUCU AGCCACAC
18420





2568
CUCUUCUG G CUCCUAUU
7573
AAUAGGAG GCCGAAAGGCGAGUGAGGUCU CAGAAGAG
18421





2604
AUGAAAAG G UCUUCUUC
7576
GAAGAAGA GCCGAAAGGCGAGUGAGGUCU CUUUUCAU
18422





2659
CAGAUGAA G UUCCUUUG
7584
CAAAGGAA GCCGAAAGGCGAGUGAGGUCU UUCAUCUG
18423





2673
UUGGAUGA G CAGUGUGA
7586
UCACACUG GCCGAAAGGCGAGUGAGGUCU UCAUCCAA
18424





2676
GAUGAGCA G UGUGAGCG
7587
CGCUCACA GCCGAAAGGCGAGUGAGGUCU UGCUCAUC
18425





2678
UGAGCAGU G UGAGCGGC
7588
GCCGCUCA GCCGAAAGGCGAGUGAGGUCU ACUGCUCA
18426





2682
CAGUGUGA G CGGCUCCC
7589
GGGACCCG GCCGAAAGGCGAGUGAGGUCU UCACACUG
18427





2685
UGUGAGCG G CUCCCUUA
7590
UAAGGGAG GCCGAAAGGCGAGUGAGGUCU CGCUCACA
18428





2698
CUUAUGAU G CCAGCAAG
7592
CUUGCUGG GCCGAAAGGCGAGUGAGGUCU AUCAUAAG
18429





2702
UGAUGCCA G CAAGUGGG
7593
CCCACUUG GCCGAAAGGCGAGUGAGGUCU UGGCAUCA
18430





2706
GCCAGCAA G UGGGAGUU
7594
AACUCCCA GCCGAAAGGCGAGUGAGGUCU UUGCUGGC
18431





2712
AAGUGGGA G UUUGCCCG
7595
CGGGCAAA GCCGAAAGGCGAGUGAGGUCU UCCCACUU
18432





2716
GGGAGUUU G CCCGGGAG
7596
CUCCCGGG GCCGAAAGGCGAGUGAGGUCU AAACUCCC
18433





2738
UAAACUGG G CAAAUCAC
7599
GUGAUUUC GCCGAAAGGCGAGUGAGGUCU CCAGUUUA
18434





2758
GAAGAGGG G CUUUUGGA
7601
UCCAAAAG GCCGAAAGGCGAGUGAGGUCU CCCUCUUC
18435





2770
UUGGAAAA G UGGUUCAA
7602
UUGAACCA GCCGAAAGGCGAGUGAGGUCU UUUUCCAA
18436





2773
GAAAAGUG G UUCAAGCA
7603
UGCUUGAA GCCGAAAGGCGAGUGAGGUCU CACUUUUC
18437





2779
UGGUUCAA G CAUCAGCA
7604
UGCUGAUG GCCGAAAGGCGAGUGAGGUCU UUGAACCA
18438





2785
AAGCAUCA G CAUUUGGC
7605
GCCAAAUG GCCGAAAGGCGAGUGAGGUCU UGAUGCUU
18439





2792
AGCAUUUG G CAUUAAGA
7606
UCUUAAUG GCCGAAAGGCGAGUGAGGUCU CAAAUGCU
18440





2811
UCACCUAC G UGCCGGAC
7608
GUCCGGCA GCCGAAAGGCGAGUGAGGUCU GUAGGUGA
18441





2813
ACCUACGU G CCGGACUG
7609
CAGUCCGG GCCGAAAGGCGAGUGAGGUCU ACGUAGGU
18442





2821
GCCGGACU G UGGCUGUG
7611
CACAGCCA GCCGAAAGGCGAGUGAGGUCU AGUCCGGC
18443





2824
GGACUGUG G CUGUGAAA
7612
UUUCACAG GCCGAAAGGCGAGUGAGGUCU CACAGUCC
18444





2827
CUGUGGCU G UGAAAAUG
7613
CAUUUUCA GCCGAAAGGCGAGUGAGGUCU AGCCACAG
18445





2835
GUGAAAAU G CUGAAAGA
7615
UCUUUCAG GCCGAAAGGCGAGUGAGGUCU AUUUUCAC
18446





2848
AAGAGGGG G CCACGGCC
7616
GGCCGUGG GCCGAAAGGCGAGUGAGGUCU CCCCUCUU
18447





2854
GGGCCACG G CCAGCGAG
7617
CUCGCUGG GCCGAAAGGCGAGUGAGGUCU CGUGGCCC
18448





2858
CACGGCCA G CGAGUACA
7618
UGUACUCG GCCGAAAGGCGAGUGAGGUCU UGGCCGUG
18449





2862
GCCAGCGA G UACAAAGC
7619
GCUUUGUA GCCGAAAGGCGAGUGAGGUCU UCGCUGGC
18450





2869
AGUACAAA G CUCUGAUG
7620
CAUCAGAG GCCGAAAGGCGAGUGAGGUCU UUUGUACU
18451





2883
AUGACUGA G CUAAAAAU
7623
AUUUUUAG GCCGAAAGGCGAGUGAGGUCU UCAGUCAU
18452





2906
CCACAUUG G CCACCAUC
7626
GAUGGUGG GCCGAAAGGCGAGUGAGGUCU CAAUGUGG
18453





2920
AUCUGAAC G UGGUUAAC
7628
GUUAACCA GCCGAAAGGCGAGUGAGGUCU GUUCAGAU
18454





2923
UGAACGUG G UUAACCUG
7629
CAGGUUAA GCCGAAAGGCGAGUGAGGUCU CACGUUCA
18455





2931
GUUAACCU G CUGGGAGC
7631
GCUCCCAG GCCGAAAGGCGAGUGAGGUCU AGGUUAAC
18456





2938
UGCUGGGA G CCUGCACC
7632
GGUGCAGG GCCGAAAGGCGAGUGAGGUCU UCCCAGCA
18457





2942
GGGAGCCU G CACCAAGC
7633
GCUUGGUG GCCGAAAGGCGAGUGAGGUCU AGGCUCCC
18458





2949
UGCACCAA G CAAGGAGG
7634
CCUCCUUG GCCGAAAGGCGAGUGAGGUCU UUGGUGCA
18459





2958
CAAGGAGG G CCUCUGAU
7635
AUCAGAGG GCCGAAAGGCGAGUGAGGUCU CCUCCUUG
18460





2968
CUCUGAUG G UGAUUGUU
7637
AACAAUCA GCCGAAAGGCGAGUGAGGUCU CAUCAGAG
18461





2974
UGGUGAUU G UUGAAUAC
7639
GUAUUCAA GCCGAAAGGCGAGUGAGGUCU AAUCACCA
18462





2984
UGAAUACU G CAAAUAUG
7641
CAUAUUUG GCCGAAAGGCGAGUGAGGUCU AGUAUUCA
18463





3017
CCUCAAGA G CAAACGUG
7645
CACGUUUG GCCGAAAGGCGAGUGAGGUCU UCUUGAGG
18464





3023
GAGCAAAC G UGACUUAU
7647
AUAAGUCA GCCGAAAGGCGAGUGAGGUCU GUUUGCUC
18465





3049
ACAAGGAU G CAGCACUA
7651
UAGUGCUG GCCGAAAGGCGAGUGAGGUCU AUCCUUGU
18466





3052
AGGAUGCA G CACUACAC
7652
GUGUAGUG GCCGAAAGGCGAGUGAGGUCU UGCAUCCU
18467





3066
CACAUGGA G CCUAAGAA
7653
UUCUUAGG GCCGAAAGGCGAGUGAGGUCU UCCAUGUG
18468





3087
AAAAUGGA G CCAGGCCU
7655
AGGCCUGG GCCGAAAGGCGAGUGAGGUCU UCCAUUUU
18469





3092
GGAGCCAG G CCUGGAAC
7656
GUUCCAGG GCCGAAAGGCGAGUGAGGUCU CUGGCUCC
18470





3104
GGAACAAG G CAAGAAAC
7658
GUUUCUUG GCCGAAAGGCGAGUGAGGUCU CUUGUUCC
18471





3125
ACUAGAUA G CGUCACCA
7662
UGGUGACG GCCGAAAGGCGAGUGAGGUCU UAUCUAGU
18472





3127
UAGAUAGC G UCACCAGC
7663
GCUGGUGA GCCGAAAGGCGAGUGAGGUCU GCUAUCUA
18473





3134
CGUCACCA G CAGCGAAA
7664
UUUCGCUG GCCGAAAGGCGAGUGAGGUCU UGGUGACG
18474





3137
CACCAGCA G CGAAAGCU
7665
AGCUUUCG GCCGAAAGGCGAGUGAGGUCU UGCUGGUG
18475





3143
CAGCGAAA G CUUUGCGA
7666
UCGCAAAG GCCGAAAGGCGAGUGAGGUCU UUUCGCUG
18476





3148
AAAGCUUU G CGAGCUCC
7667
GGAGCUCG GCCGAAAGGCGAGUGAGGUCU AAAGCUUU
18477





3152
CUUUGCGA G CUCCGGCU
7668
AGCCGGAG GCCGAAAGGCGAGUGAGGUCU UCGCAAAG
18478





3158
GAGCUCCG G CUUUCAGG
7669
CCUGAAAG GCCGAAAGGCGAGUGAGGUCU CGGAGCUC
18479





3176
AGAUAAAA G UCUGAGUG
7671
CACUCAGA GCCGAAAGGCGAGUGAGGUCU UUUUAUCU
18480





3182
AAGUCUGA G UGAUGUUG
7672
CAACAUCA GCCGAAAGGCGAGUGAGGUCU UCAGACUU
18481





3187
UGAGUGAU G UUGAGGAA
7674
UUCCUCAA GCCGAAAGGCGAGUGAGGUCU AUCACUCA
18482





3212
UUCUGACG G UUUCUACA
7677
UGUAGAAA GCCGAAAGGCGAGUGAGGUCU CGUCAGAA
18483





3225
UACAAGGA G CCCAUCAC
7678
GUGAUGGG GCCGAAAGGCGAGUGAGGUCU UCCUUGUA
18484





3257
UUCUUACA G UUUUCAAG
7681
CUUGAAAA GCCGAAAGGCGAGUGAGGUCU UGUAAGAA
18485





3265
GUUUUCAA G UGGCCAGA
7682
UCUGGCCA GCCGAAAGGCGAGUGAGGUCU UUGAAAAC
18486





3268
UUCAAGUG G CCAGAGGC
7683
GCCUCUGG GCCGAAAGGCGAGUGAGGUCU CACUUGAA
18487





3275
GGCCAGAG G CAUGGAGU
7684
ACUCCAUG GCCGAAAGGCGAGUGAGGUCU CUCUGGCC
18488





3282
GGCAUGGA G UUCCUGUC
7685
GACAGGAA GCCGAAAGGCGAGUGAGGUCU UCCAUGCC
18489





3288
GAGUUCCU G UCUUCCAG
7686
CUGGAAGA GCCGAAAGGCGAGUGAGGUCU AGGAACUC
18490





3300
UCCAGAAA G UGCAUUCA
7687
UGAAUGCA GCCGAAAGGCGAGUGAGGUCU UUUCUGGA
18491





3302
CAGAAAGU G CAUUCAUC
7688
GAUGAAUG GCCGAAAGGCGAGUGAGGUCU ACUUUCUG
18492





3319
GGGACCUG G CAGCGAGA
7690
UCUCGCUG GCCGAAAGGCGAGUGAGGUCU CAGGUCCC
18493





3322
ACCUGGCA G CGAGAAAC
7691
GUUUCUCG GCCGAAAGGCGAGUGAGGUCU UGCCAGGU
18494





3352
AGAACAAC G UGGUGAAG
7695
CUUCACCA GCCGAAAGGCGAGUGAGGUCU GUUGUUCU
18495





3355
ACAACGUG G UGAAGAUU
7696
AAUCUUCA GCCGAAAGGCGAGUGAGGUCU CACGUUGU
18496





3365
GAAGAUUU G UGAUUUUG
7698
CAAAAUCA GCCGAAAGGCGAGUGAGGUCU AAAUCUUC
18497





3374
UGAUUUUG G CCUUGCCC
7700
GGGCAAGG GCCGAAAGGCGAGUGAGGUCU CAAAAUCA
18498





3379
UUGGCCUU G CCCGGGAU
7701
AUCCCGGG GCCGAAAGGCGAGUGAGGUCU AAGGCCAA
18499





3409
CCGAUUAU G UGAGAAAA
7705
UUUUCUCA GCCGAAAGGCGAGUGAGGUCU AUAAUCGG
18500





3448
AAUGGAUG G CUCCCGAA
7710
UUCGGGAG GCCGAAAGGCGAGUGAGGUCU CAUCCAUU
18501





3479
AAUCUACA G CACCAAGA
7714
UCUUGGUG GCCGAAAGGCGAGUGAGGUCU UGUAGAUU
18502





3488
CACCAAGA G CGACGUGU
7715
ACACGUCG GCCGAAAGGCGAGUGAGGUCU UCUUGGUG
18503





3493
AGAGCGAC G UGUGGUCU
7717
AGACCACA GCCGAAAGGCGAGUGAGGUCU GUCGCUCU
18504





3495
AGCGACGU G UGGUCUUA
7718
UAAGACCA GCCGAAAGGCGAGUGAGGUCU ACGUCGCU
18505





3498
GACGUGUG G UCUUACGG
7719
CCGUAAGA GCCGAAAGGCGAGUGAGGUCU CACACGUC
18506





3508
CUUACGGA G UAUUGCUG
7720
CAGCAAUA GCCGAAAGGCGAGUGAGGUCU UCCGUAAG
18507





3513
GGAGUAUU G CUGUGGGA
7721
UCCCACAG GCCGAAAGGCGAGUGAGGUCU AAUACUCC
18508





3516
GUAUUGCU G UGGGAAAU
7722
AUUUCCCA GCCGAAAGGCGAGUGAGGUCU AGCAAUAC
18509





3536
CUCCUUAG G UGGGUCUC
7724
GAGACCCA GCCGAAAGGCGAGUGAGGUCU CUAAGGAG
18510





3540
UUAGGUGG G UCUCCAUA
7725
UAUGGAGA GCCGAAAGGCGAGUGAGGUCU CCACCUAA
18511





3556
ACCCAGGA G UACAAAUG
7726
CAUUUGUA GCCGAAAGGCGAGUGAGGUCU UCCUGGGU
18512





3578
GGACUUUU G CAGUCGCC
7730
GGCGACUG GCCGAAAGGCGAGUGAGGUCU AAAAGUCC
18513





3581
CUUUUGCA G UCGCCUGA
7731
UCAGGCGA GCCGAAAGGCGAGUGAGGUCU UGCAAAAG
18514





3584
UUGCAGUC G CCUGAGGG
7732
CCCUCAGG GCCGAAAGGCGAGUGAGGUCU GACUGCAA
18515





3596
GAGGGAAG G CAUGAGGA
7733
UCCUCAUG GCCGAAAGGCGAGUGAGGUCU CUUCCCUC
18516





3610
GGAUGAGA G CUCCUGAG
7735
CUCAGGAG GCCGAAAGGCGAGUGAGGUCU UCUCAUCC
18517





3618
GCUCCUGA G UACUCUAC
7736
GUAGAGUA GCCGAAAGGCGAGUGAGGUCU UCAGGAGC
18518





3648
CAGAUCAU G CUGGACUG
7739
CAGUCCAG GCCGAAAGGCGAGUGAGGUCU AUGAUCUG
18519





3656
GCUGGACU G CUGGCACA
7741
UGUGCCAG GCCGAAAGGCGAGUGAGGUCU AGUCCAGC
18520





3660
GACUGCUG G CACAGAGA
7742
UCUCUGUG GCCGAAAGGCGAGUGAGGUCU CAGCAGUC
18521





3681
AAAGAAAG G CCAAGAUU
7744
AAUCUUGG GCCGAAAGGCGAGUGAGGUCU CUUUCUUU
18522





3691
CAAGAUUU G CAGAACUU
7746
AAGUUCUG GCCGAAAGGCGAGUGAGGUCU AAAUCUUG
18523





3700
CAGAACUU G UGGAAAAA
7748
UUUUUCCA GCCGAAAGGCGAGUGAGGUCU AAGUUCUG
18524





3713
AAAACUAG G UGAUUUGC
7750
GCAAAUCA GCCGAAAGGCGAGUGAGGUCU CUAGUUUU
18525





3720
GGUGAUUU G CUUCAAGC
7752
GCUUGAAG GCCGAAAGGCGAGUGAGGUCU AAAUCACC
18526





3727
UGCUUCAA G CAAAUGUA
7753
UACAUUUG GCCGAAAGGCGAGUGAGGUCU UUGAAGCA
18527





3733
AAGCAAAU G UACAACAG
7755
CUGUUGUA GCCGAAAGGCGAGUGAGGUCU AUUUGCUU
18528





3746
ACAGGAUG G UAAAGACU
7758
AGUCUUUA GCCGAAAGGCGAGUGAGGUCU CAUCCUGU
18529





3769
CAAUCAAU G CCAUACUG
7762
CAGUAUGG GCCGAAAGGCGAGUGAGGUCU AUUGAUUG
18530





3788
AGGAAAUA G UGGGUUUA
7765
UAAACCCA GCCGAAAGGCGAGUGAGGUCU UAUUUCCU
18531





3792
AAUAGUGG G UUUACAUA
7766
UAUGUAAA GCCGAAAGGCGAGUGAGGUCU CCACUAUU
18532





3811
CAACUCCU G CCUUCUCU
7768
AGAGAAGG GCCGAAAGGCGAGUGAGGUCU AGGAGUUG
18533





3839
CAAGGAAA G UAUUUCAG
7770
CUGAAAUA GCCGAAAGGCGAGUGAGGUCU UUUCCUUG
18534





3847
GUAUUUCA G CUCCGAAG
7771
CUUCGGAG GCCGAAAGGCGAGUGAGGUCU UGAAAUAC
18535





3855
GCUCCGAA G UUUAAUUC
7772
GAAUUAAA GCCGAAAGGCGAGUGAGGUCU UUCGGAGC
18536





3869
UUCAGGAA G CUCUGAUG
7774
CAUCAGAG GCCGAAAGGCGAGUGAGGUCU UUCCUGAA
18537





3880
CUGAUGAU G UCAGAUAU
7777
AUAUCUGA GCCGAAAGGCGAGUGAGGUCU AUCAUCAG
18538





3889
UCAGAUAU G UAAAUGCU
7779
AGCAUUUA GCCGAAAGGCGAGUGAGGUCU AUAUCUGA
18539





3895
AUGUAAAU G CUUUCAAG
7781
CUUGAAAG GCCGAAAGGCGAGUGAGGUCU AUUUACAU
18540





3903
GCUUUCAA G UUCAUGAG
7782
CUCAUGAA GCCGAAAGGCGAGUGAGGUCU UUGAAAGC
18541





3911
GUUCAUGA G CCUGGAAA
7783
UUUCCAGG GCCGAAAGGCGAGUGAGGUCU UCAUGAAC
18542





3952
UACCGAAU G CCACCUCC
7788
GGAGGUGG GCCGAAAGGCGAGUGAGGUCU AUUCGGUA
18543





3963
ACCUCCAU G UUUGAUGA
7789
UCAUCAAA GCCGAAAGGCGAGUGAGGUCU AUGGAGGU
18544





3980
CUACCAGG G CGACAGCA
7792
UGCUGUCG GCCGAAAGGCGAGUGAGGUCU CCUGGUAG
18545





3986
GGGCGACA G CAGCACUC
7794
GAGUGCUG GCCGAAAGGCGAGUGAGGUCU UGUCGCCC
18546





3989
CGACAGCA G CACUCUGU
7795
ACAGAGUG GCCGAAAGGCGAGUGAGGUCU UGCUGUCG
18547





3996
AGCACUCU G UUGGCCUC
7796
GAGGCCAA GCCGAAAGGCGAGUGAGGUCU AGAGUGCU
18548





4000
CUCUGUUG G CCUCUCCC
7797
GGGAGAGG GCCGAAAGGCGAGUGAGGUCU CAACAGAG
18549





4011
UCUCCCAU G CUGAAGCG
7798
CGCUUCAG GCCGAAAGGCGAGUGAGGUCU AUGGGAGA
18550





4017
AUGCUGAA G CGCUUCAC
7799
GUGAAGCG GCCGAAAGGCGAGUGAGGUCU UUCAGCAU
18551





4019
GCUGAAGC G CUUCACCU
7800
AGGUGAAG GCCGAAAGGCGAGUGAGGUCU GCUUCAGC
18552





4037
GACUGACA G CAAACCCA
7803
UGGGUUUG GCCGAAAGGCGAGUGAGGUCU UGUCAGUC
18553





4048
AACCCAAG G CCUCGCUC
7805
GAGCGAGG GCCGAAAGGCGAGUGAGGUCU CUUGGGUU
18554





4053
AAGGCCUC G CUCAAGAU
7806
AUCUUGAG GCCGAAAGGCGAGUGAGGUCU GAGGCCUU
18555





4072
ACUUGAGA G UAACCAGU
7809
ACUGGUUA GCCGAAAGGCGAGUGAGGUCU UCUCAAGU
18556





4079
AGUAACCA G UAAAAGUA
7811
UACUUUUA GCCGAAAGGCGAGUGAGGUCU UGGUUACU
18557





4085
CAGUAAAA G UAAGGAGU
7812
ACUCCUUA GCCGAAAGGCGAGUGAGGUCU UUUUACUG
18558





4092
AGUAAGGA G UCGGGGCU
7813
AGCCCCGA GCCGAAAGGCGAGUGAGGUCU UCCUUACU
18559





4098
GAGUCGGG G CUGUCUGA
7814
UCAGACAG GCCGAAAGGCGAGUGAGGUCU CCCGACUC
18560





4101
UCGGGGCU G UCUGAUGU
7815
ACAUCAGA GCCGAAAGGCGAGUGAGGUCU AGCCCCGA
18561





4108
UGUCUGAU G UCAGCAGG
7817
CCUGCUGA GCCGAAAGGCGAGUGAGGUCU AUCAGACA
18562





4112
UGAUGUCA G CAGGCCCA
7818
UGGGCCUG GCCGAAAGGCGAGUGAGGUCU UGACAUCA
18563





4116
GUCAGCAG G CCCAGUUU
7819
AAACUGGG GCCGAAAGGCGAGUGAGGUCU CUGCUGAC
18564





4121
CAGGCCCA G UUUCUGCC
7820
GGCAGAAA GCCGAAAGGCGAGUGAGGUCU UGGGCCUG
18565





4127
CAGUUUCU G CCAUUCCA
7821
UGGAAUGG GCCGAAAGGCGAGUGAGGUCU AGAAACUG
18566





4136
CCAUUCCA G CUGUGGGC
7822
GCCCACAG GCCGAAAGGCGAGUGAGGUCU UGGAAUGG
18567





4139
UUCCAGCU G UGGGCACG
7823
CGUGCCCA GCCGAAAGGCGAGUGAGGUCU AGCUGGAA
18568





4143
AGCUGUGG G CACGUCAG
7824
CUGACGUG GCCGAAAGGCGAGUGAGGUCU CCACAGCU
18569





4147
GUGGGCAC G UCAGCGAA
7825
UUCGCUGA GCCGAAAGGCGAGUGAGGUCU GUGCCCAC
18570





4151
GCACGUCA G CGAAGGCA
7826
UGCCUUCG GCCGAAAGGCGAGUGAGGUCU UGACGUGC
18571





4157
CAGCGAAG G CAAGCGCA
7827
UGCGCUUG GCCGAAAGGCGAGUGAGGUCU CUUCGCUG
18572





4161
GAAGGCAA G CGCAGGUU
7828
AACCUGCG GCCGAAAGGCGAGUGAGGUCU UUGCCUUC
18573





4163
AGGCAAGC G CAGGUUCA
7829
UGAACCUG GCCGAAAGGCGAGUGAGGUCU GCUUGCCU
18574





4167
AAGCGCAG G UUCACCUA
7830
UAGGUGAA GCCGAAAGGCGAGUGAGGUCU CUGCGCUU
18575





4183
ACGACCAC G CUGAGCUG
7832
CAGCUCAG GCCGAAAGGCGAGUGAGGUCU GUGGUCGU
18576





4188
CACGCUGA G CUGGAAAG
7833
CUUUCCAG GCCGAAAGGCGAGUGAGGUCU UCAGCGUG
18577





4204
GGAAAAUC G CGUGCUGC
7835
GCAGCACG GCCGAAAGGCGAGUGAGGUCU GAUUUUCC
18578





4206
AAAAUCGC G UGCUGCUC
7836
GAGCAGCA GCCGAAAGGCGAGUGAGGUCU GCGAUUUU
18579





4208
AAUCGCGU G CUGCUCCC
7837
GGGAGCAG GCCGAAAGGCGAGUGAGGUCU ACGCGAUU
18580





4211
CGCGUGCU G CUCCCCGC
7838
GCGGGGAG GCCGAAAGGCGAGUGAGGUCU AGCACGCG
18581





4218
UGCUCCCC G CCCCCAGA
7839
UCUGGGGG GCCGAAAGGCGAGUGAGGUCU GGGGAGCA
18582





4237
ACAACUCG G UGGUCCUG
7842
CAGGACCA GCCGAAAGGCGAGUGAGGUCU CGAGUUGU
18583





4240
ACUCGGUG G UCCUGUAC
7843
GUACAGGA GCCGAAAGGCGAGUGAGGUCU CACCGAGU
18584





4245
GUGGUCCU G UACUCCAC
7844
GUGGAGUA GCCGAAAGGCGAGUGAGGUCU AGGACCAC
18585





4268
CAUCUAGA G UUUGACAC
7845
GUGUCAAA GCCGAAAGGCGAGUGAGGUCU UCUAGAUG
18586





4280
GACACGAA C CCUUAUUU
7847
AAAUAAGG GCCGAAAGGCGAGUGAGGUCU UUCGUGUC
18587





4295
UUCUAGAA G CACAUGUG
7848
CACAUGUG GCCGAAAGGCGAGUGAGGUCU UUCUAGAA
18588





4301
AAGCACAU G UGUAUUUA
7849
UAAAUACA GCCGAAAGGCGAGUGAGGUCU AUGUGCUU
18589





4303
GCACAUGU G UAUUUAUA
7850
UAUAAAUA GCCGAAAGGCGAGUGAGGUCU ACAUGUGC
18590





4326
GGAAACUA G CUUUUGCC
7852
GGCAAAAG GCCGAAAGGCGAGUGAGGUCU UAGUUUCC
18591





4332
UAGCUUUU G CCAGUAUU
7853
AAUACUGG GCCGAAAGGCGAGUGAGGUCU AAAAGCUA
18592





4336
UUUUGCCA G UAUUAUGC
7854
GCAUAAUA GCCGAAAGGCGAGUGAGGUCU UGGCAAAA
18593





4343
AGUAUUAU G CAUAUAUA
7855
UAUAUAUG GCCGAAAGGCGAGUGAGGUCU AUAAUACU
18594





4353
AUAUAUAA G UUUACACC
7856
GGUGUAAA GCCGAAAGGCGAGUGAGGUCU UUAUAUAU
18595





4379
CCAUGGGA G CCAGCUGC
7857
GCAGCUGG GCCGAAAGGCGAGUGAGGUCU UCCCAUGG
18596





4383
GGGAGCCA G CUGCUUUU
7858
AAAAGCAG GCCGAAAGGCGAGUGAGGUCU UGGCUCCC
18597





4386
AGCCAGCU G CUUUUUGU
7859
ACAAAAAG GCCGAAAGGCGAGUGAGGUCU AGCUGGCU
18598





4393
UGCUUUUU G UGAUUUUU
7860
AAAAAUCA GCCGAAAGGCGAGUGAGGUCU AAAAAGCA
18599





4408
UUUUAAUA G UGCUUUUU
7863
AAAAAGCA GCCGAAAGGCGAGUGAGGUCU UAUUAAAA
18600





4410
UUAAUAGU G CUUUUUUU
7864
AAAAAAAG GCCGAAAGGCGAGUGAGGUCU ACUAUUAA
18601





4336
ACAAGAAU G UAACUCCA
7868
UGGAGUUA GCCGAAAGGCGAGUGAGGUCU AUUCUUGU
18602





4457
GAGAAAUA G UGACAAGU
7872
ACUUGUCA GCCGAAAGGCGAGUGAGGUCU UAUUUCUC
18603





4464
AGUGACAA G UGAAGAAC
7874
GUUCUUCA GCCGAAAGGCGAGUGAGGUCU UUGUCACU
18604





4479
ACACUACU G CUAAAUCC
7876
GGAUUUAG GCCGAAAGGCGAGUGAGGUCU AGUAGUGU
18605





4492
AUCCUCAU G UUACUCAG
7878
CUGAGUAA GCCGAAAGGCGAGUGAGGUCU AUGAGGAU
18606





4500
GUUACUCA G UGUUAGAG
7879
CUCUAACA GCCGAAAGGCGAGUGAGGUCU UGAGUAAC
18607





4502
UACUCAGU G UUAGAGAA
7880
UUCUCUAA GCCGAAAGGCGACUGAGCUCU ACUGAGUA
18608





4538
ACUUCCCU G CUCCAACC
7885
GGUUGGAG GCCGAAAGGCGAGUGAGGUCU AGGGAAGU
18609





4550
CAACCCCC G CCACCUCA
7887
UGAGGUGG GCCGAAAGGCGAGUGAGGUCU GGGGGUUG
18610





4561
ACCUCAGG G CACGCAGG
7888
CCUGCGUG GCCGAAAGGCGAGUGAGGUCU CCUGAGGU
18611





4565
CAGGGCAC G CAGGACCA
7889
UGGUCCUG GCCGAAAGGCGAGUGAGGUCU GUGCCCUG
18612





4574
CAGGACCA G UUUGAUUG
7891
CAAUCAAA GCCGAAAGGCGAGUGAGGUCU UGGUCCUG
18613





4587
AUUGAGGA G CUGCACUG
7893
CAGUGCAG GCCGAAAGGCGAGUGAGGUCU UCCUCAAU
18614





4590
GAGGAGCU G CACUGAUC
7894
GAUCAGUG GCCGAAAGGCGAGUGAGGUCU AGCUCCUC
18615





4606
CACCCAAU G CAUCACGU
7897
ACGUGAUG GCCGAAAGGCGAGUGAGGUCU AUUGGGUG
18616





4613
UGCAUCAC G UACCCCAC
7898
GUGGGGUA GCCGAAAGGCGAGUGAGGUCU GUGAUGCA
18617





4625
CCCACUGG G CCAGCCCU
7899
AGGGCUGG GCCGAAAGGCGAGUGAGGUCU CCAGUGGG
18618





4629
CUGGGCCA G CCCUGCAG
7900
CUGCAGGG GCCGAAAGGCGAGUGAGGUCU UGGCCCAG
18619





4634
CCAGCCCU G CAGCCCAA
7901
UUGGGCUG GCCGAAAGGCGAGUGAGGUCU AGGGCUGG
18620





4637
GCCCUGCA G CCCAAAAC
7902
GUUUUGGG GCCGAAAGGCGAGUGAGGUCU UGCAGGGC
18621





4651
AACCCAGG G CAACAAGC
7904
GCUUGUUG GCCGAAAGGCGAGUGAGGUCU CCUGGGUU
18622





4658
GGCAACAA G CCCGUUAG
7906
CUAACGGG GCCGAAAGGCGAGUGAGGUCU UUGUUGCC
18623





4662
ACAAGCCC G UUAGCCCC
7907
GGGGCUAA GCCGAAAGGCGAGUGAGGUCU GGGCUUGU
18624





4666
GCCCGUUA G CCCCAGGG
7908
CCCUGGGG GCCGAAAGGCGAGUGAGGUCU UAACGGGC
18625





4683
GAUCACUG G CUGGCCUG
7910
CAGGCCAC GCCGAAAGGCGAGUGAGGUCU CAGUGAUC
18626





4687
ACUGGCUG G CCUGAGCA
7911
UGCUCAGG GCCGAAAGGCGAGUGAGGUCU CAGCCAGU
18627





4693
UGGCCUGA G CAACAUCU
7912
AGAUGUUG GCCGAAAGGCGAGUGAGGUCU UCAGGCCA
18628





4707
UCUCGGGA G UCCUCUAC
7914
CUAGAGGA GCCGAAAGGCGAGUGAGGUCU UCCCGAGA
18629





4715
GUCCUCUA G CAGGCCUA
7915
UAGGCCUG GCCGAAAGGCGAGUGAGGUCU UAGAGGAC
18630





4719
UCUAGCAG G CCUAAGAC
7916
GUCUUAGG GCCGAAAGGCGAGUGAGGUCU CUGCUAGA
18631





4730
UAAGACAU G UGAGGAGG
7918
CCUCCUCA GCCGAAAGGCGAGUGAGGUCU AUGUCUUA
18632





4752
GAAAAAAA G CAAAAAGC
7919
GCUUUUUG GCCGAAAGGCGAGUGAGGUCU UUUUUUUC
18633





4759
AGCAAAAA G CAAGGGAG
7920
CUCCCUUG GCCGAAAGGCGAGUGAGGUCU UUUUUGCU
18634





4788
GGGAGAAG G CAUGAGAA
7922
UUCUCAUG GCCGAAAGGCGAGUGAGGUCU CUUCUCCC
18635





4809
UUUGAGAC G CACCAUGU
7925
ACAUGGUG GCCGAAAGGCGAGUGAGGUCU GUCUCAAA
18636





4816
CGCACCAU G UGGGCACG
7926
CGUGCCCA GCCGAAAGGCGAGUGAGGUCU AUGGUGCG
18637





4820
CCAUGUGG G CACGGAGG
7927
CCUCCGUG GCCGAAAGGCGAGUGAGGUCU CCACAUGG
18638





4837
GGGACGGG G CUCAGCAA
7929
UUGCUGAG GCCGAAAGGCGAGUGAGGUCU CCCGUCCC
18639





4842
GGGGCUCA G CAAUGCCA
7930
UGGCAUUG GCCGAAAGGCGAGUGAGGUCU UGAGCCCC
18640





4847
UCAGCAAU G CCAUUUCA
7932
UGAAAUGG GCCGAAAGGCGAGUGAGGUCU AUUGCUGA
18641





4856
CCAUUUCA G UGGCUUCC
7933
GGAAGCCA GCCGAAAGGCGAGUGAGGUCU UGAAAUGG
18642





4859
UUUCAGUG G CUUCCCAG
7934
CUGGGAAG GCCGAAAGGCGAGUGAGGUCU CACUGAAA
18643





4867
GCUUCCCA G CUCUGACC
7935
GGUCAGAG GCCGAAAGGCGAGUGAGGUCU UGGGAAGC
18644





4891
AUUUGAGG G CCCAGCCA
7937
UGGCUGGG GCCGAAAGGCGAGUGAGGUCU CCUCAAAU
18645





4896
AGGGCCCA G CCAGGAGC
7938
GCUCCUGG GCCGAAAGGCGAGUGAGGUCU UGGGCCCU
18646





4903
AGCCAGGA G CAGAUGGA
7939
UCCAUCUG GCCGAAAGGCGAGUGAGGUCU UCCUGGCU
18647





4914
GAUGGACA G CGAUGAGG
7942
CCUCAUCG GCCGAAAGGCGAGUGAGGUCU UGUCCAUC
18648





4946
UCUGGGAG G CAAGAAAA
7946
UUUUCUUG GCCGAAAGGCGAGUGAGGUCU CUCCCAGA
18649





4981
GAACUAAA G CAAAUUUU
7950
AAAAUUUG GCCGAAAGGCGAGUGAGGUCU UUUAGUUC
18650





5008
CUAUGGAA G UGGUUCUA
7953
UAGAACCA GCCGAAAGGCGAGUGAGGUCU UUCCAUAG
18651





5011
UGGAAGUG G UUCUAUGU
7954
ACAUAGAA GCCGAAAGGCGAGUGAGGUCU CACUUCCA
18652





5018
GGUUCUAU G UCCAUUCU
7955
AGAAUGGA GCCGAAAGGCGAGUGAGGUCU AUAGAACC
18653





5032
UCUCAUUC G UGGCAUGU
7956
ACAUGCCA GCCGAAAGGCGAGUGAGGUCU GAAUGAGA
18654





5035
CAUUCGUG G CAUGUUUU
7957
AAAACAUG GCCGAAAGGCGAGUGAGGUCU CACGAAUG
18655





5039
CGUGGCAU G UUUUGAUU
7958
AAUCAAAA GCCGAAAGGCGAGUGAGGUCU AUGCCACG
18656





5049
UUUGAUUU G UAGCACUG
7960
CAGUGCUA GCCGAAAGGCGAGUGAGGUCU AAAUCAAA
18657





5052
GAUUUGUA G CACUGAGG
7961
CCUCAGUG GCCGAAAGGCGAGUGAGGUCU UACAAAUC
18658





5061
CACUGAGG G UGGCACUC
7962
GAGUGCCA GCCGAAAGGCGAGUGAGGUCU CCUCAGUG
18659





5064
UGAGGGUG G CACUCAAC
7963
GUUGAGUG GCCGAAAGGCGAGUGAGGUCU CACCCUCA
18660





5078
AACUCUGA G CCCAUACU
7965
AGUAUGGG GCCGAAAGGCGAGUGAGGUCU UCAGAGUU
18661





5091
UACUUUUG G CUCCUCUA
7966
UAGAGGAG GCCGAAAGGCGAGUGAGGUCU CAAAAGUA
18662





5100
CUCCUCUA G UAAGAUGC
7967
GCAUCUUA GCCGAAAGGCGAGUGAGGUCU UAGAGGAG
18663





5107
AGUAAGAU G CACUGAAA
7969
UUUCAGUG GCCGAAAGGCGAGUGAGGUCU AUCUUACU
18664





5121
AAAACUUA G CCAGAGUU
7971
AACUCUGG GCCGAAAGGCGAGUGAGGUCU UAAGUUUU
18665





5127
UAGCCAGA G UUAGGUUG
7972
CAACCUAA GCCGAAAGGCGAGUGAGGUCU UCUGGCUA
18666





5132
AGAGUUAG G UUGUCUCC
7973
GGAGACAA GCCGAAAGGCGAGUGAGGUCU CUAACUCU
18667





5135
GUUAGGUU G UCUCCAGG
7974
CCUGGAGA GCCGAAAGGCGAGUGAGGUCU AACCUAAC
18668





5143
GUCUCCAG G CCAUGAUG
7975
CAUCAUGG GCCGAAAGGCGAGUGAGGUCU CUGGAGAC
18669





5152
CCAUGAUG G CCUUACAC
7977
GUGUAAGG GCCGAAAGGCGAGUGAGGUCU CAUCAUGG
18670





5168
CUGAAAAU G UCACAUUC
7979
GAAUGUGA GCCGAAAGGCGAGUGAGGUCU AUUUUCAG
18671





5185
UAUUUUGG G UAUUAAUA
7980
UAUUAAUA GCCGAAAGGCGAGUGAGGUCU CCAAAAUA
18672





5198
AAUAUAUA G UCCAGACA
7982
UGUCUGGA GCCGAAAGGCGAGUGAGGUCU UAUAUAUU
18673





5224
AUUUCUUG G UAUUAUUC
7986
GAAUAAUA GCCGAAAGGCGAGUGAGGUCU CAAGAAAU
18674





5234
AUUAUUCU G UUUUGCAC
7987
GUGCAAAA GCCGAAAGGCGAGUGAGGUCU AGAAUAAU
18675





5239
UCUGUUUU G CACAGUUA
7988
UAACUGUG GCCGAAAGGCGAGUGAGGUCU AAAACAGA
18676





5244
UUUGCACA G UUAGUUGU
7989
ACAACUAA GCCGAAAGGCGAGUGAGGUCU UGUGCAAA
18677





5248
CACAGUUA G UUGUGAAA
7990
UUUCACAA GCCGAAAGGCGAGUGAGGUCU UAACUGUG
18678





5251
AGUUAGUU G UGAAAGAA
7991
UUCUUUCA GCCGAAAGGCGAGUGAGGUCU AACUAACU
18679





5261
GAAAGAAA G CUGAGAAG
7992
CUUCUCAG GCCGAAAGGCGAGUGAGGUCU UUUCUUUC
18680





5279
AUGAAAAU G CAGUCCUG
7995
CAGGACUG GCCGAAAGGCGAGUGAGGUCU AUUUUCAU
18681





5282
AAAAUGCA G UCCUGAGG
7996
CCUCAGGA GCCGAAAGGCGAGUGAGGUCU UGCAUUUU
18682





5294
UGAGGAGA G UUUUCUCC
7997
GGAGAAAA GCCGAAAGGCGAGUGAGGUCU UCUCCUCA
18683





5317
AAACGAGG G CUGAUGGA
7999
UCCAUCAG GCCGAAAGGCGAGUGAGGUCU CCUCGUUU
18684





5334
GGAAAAAG G UCAAUAAG
8001
CUUAUUGA GCCGAAAGGCGAGUGAGGUCU CUUUUUCC
18685





5343
UCAAUAAG G UCAAGGGA
8003
UCCCUUGA GCCGAAAGGCGAGUGAGGUCU CUUAUUGA
18686





5359
AAGACCCC G UCUCUAUA
8005
UAUAGAGA GCCGAAAGGCGAGUGAGGUCU GGGGUCUU
18687





5393
CCAACACA G UUGGGACC
8010
GGUCCCAA GCCGAAAGGCGAGUGAGGUCU UGUGUUGG
18688





5415
CACAGGAA G UCAGUCAC
8013
GUGACUGA GCCGAAAGGCGAGUGAGGUCU UUCCUGUG
18689





5419
GGAAGUCA G UCACGUUU
8014
AAACGUGA GCCGAAAGGCGAGUGAGGUCU UGACUUCC
18690





5424
UCAGUCAC G UUUCCUUU
8015
AAAGGAAA GCCGAAAGGCGAGUGAGGUCU GUGACUGA
18691





5477
GAAAGGAU G UGGAAGAG
8020
CUCUUCCA GCCGAAAGGCGAGUGAGGUCU AUCCUUUC
18692





5485
GUGGAAGA G CAUUAGCU
8021
AGCUAAUG GCCGAAAGGCGAGUGAGGUCU UCUUCCAC
18693





5491
GAGCAUUA G CUGGCGCA
8022
UGCGCCAG GCCGAAAGGCGAGUGAGGUCU UAAUGCUC
18694





5495
AUUAGCUG G CGCAUAUU
8023
AAUAUGCG GCCGAAAGGCGAGUGAGGUCU CAGCUAAU
18695





5497
UAGCUGGC G CAUAUUAA
8024
UUAAUAUG GCCGAAAGGCGAGUGAGGUCU GCCAGCUA
18696





5506
CAUAUUAA G CACUUUAA
8025
UUAAAGUG GCCGAAAGGCGAGUGAGGUCU UUAAUAUG
18697





5515
CACUUUAA G CUCCUUGA
8026
UCAAGGAG GCCGAAAGGCGAGUGAGGUCU UUAAAGUG
18698





5524
CUCCUUGA G UAAAAAGG
8027
CCUUUUUA GCCGAAAGGCGAGUGAGGUCU UCAAGGAG
18699





5532
GUAAAAAG G UGGUAUGU
8028
ACAUACCA GCCGAAAGGCGAGUGAGGUCU CUUUUUAC
18700





5535
AAAAGGUG G UAUGUAAU
8029
AUUACAUA GCCGAAAGGCGAGUGAGGUCU CACCUUUU
18701





5539
GGUGGUAU G UAAUUUAU
8030
AUAAAUUA GCCGAAAGGCGAGUGAGGUCU AUACCACC
18702





5548
UAAUUUAU G CAAGGUAU
8032
AUACCUUG GCCGAAAGGCGAGUGAGGUCU AUAAAUUA
18703





5553
UAUGCAAG G UAUUUCUC
8033
GAGAAAUA GCCGAAAGGCGAGUGAGGUCU CUUGCAUA
18704





5564
UUUCUCCA G UUGGGACU
8034
AGUCCCAA GCCGAAAGGCGAGUGAGGUCU UGGAGAAA
18705





5583
GGAUAUUA G UUAAUGAG
8037
CUCAUUAA GCCGAAAGGCGAGUGAGGUCU UAAUAUCC
18706





5591
GUUAAUGA G CCAUCACU
8039
AGUGAUGG GCCGAAAGGCGAGUGAGGUCU UCAUUAAC
18707





5609
GAAGAAAA G CCCAUUUU
8040
AAAAUGGG GCCGAAAGGCGAGUGAGGUCU UUUUCUUC
18708





5623
UUUCAACU G CUUUGAAA
8042
UUUCAAAG GCCGAAAGGCGAGUGAGGUCU AGUUGAAA
18709





5635
UGAAACUU G CCUGGGGU
8044
ACCCCAGG GCCGAAAGGCGAGUGAGGUCU AAGUUUCA
18710





5642
UGCCUGGG G UCUGAGCA
8045
UGCUCAGA GCCGAAAGGCGAGUGAGGUCU CCCAGGCA
18711





5648
GGGUCUGA G CAUGAUGG
8046
CCAUCAUG GCCGAAAGGCGAGUGAGGUCU UCAGACCC
18712





5672
GAGACAGG G UAGGAAAG
8050
CUUUCCUA GCCGAAAGGCGAGUGAGGUCU CCUGUCUC
18713





5682
AGGAAAGG G CGCCUACU
8051
AGUAGGCG GCCGAAAGGCGAGUGAGGUCU CCUUUCCU
18714





5684
GAAAGGGC G CCUACUCU
8052
AGAGUAGG GCCGAAAGGCGAGUGAGGUCU GCCCUUUC
18715





5698
UCUUCAGG G UCUAAAGA
8053
UCUUUAGA GCCGAAAGGCGAGUGAGGUCU CCUGAAGA
18716





5711
AAGAUCAA G UGGGCCUU
8055
AAGGCCCA GCCGAAAGGCGAGUGAGGUCU UUGAUCUU
18717





5715
UCAAGUGG G CCUUGGAU
8056
AUCCAAGG GCCGAAAGGCGAGUGAGGUCU CCACUUGA
18718





5725
CUUGGAUC G CUAAGCUG
8058
CAGCUUAG GCCGAAAGGCGAGUGAGGUCU GAUCCAAG
18719





5730
AUCGCUAA G CUGGCUCU
8059
AGAGCCAG GCCGAAAGGCGAGUGAGGUCU UUAGCGAU
18720





5734
CUAAGCUG G CUCUGUUU
8060
AAACAGAG GCCGAAAGGCGAGUGAGGUCU CAGCUUAG
18721





5739
CUGGCUCU G UUUGAUGC
8061
GCAUCAAA GCCGAAAGGCGAGUGAGGUCU AGAGCCAG
18722





5746
UGUUUGAU G CUAUUUAU
8063
AUAAAUAG GCCGAAAGGCGAGUGAGGUCU AUCAAACA
18723





5755
CUAUUUAU G CAAGUUAG
8064
CUAACUUG GCCGAAAGGCGAGUGAGGUCU AUAAAUAG
18724





5759
UUAUGCAA G UUAGGGUC
8065
GACCCUAA GCCGAAAGGCGAGUGAGGUCU UUGCAUAA
18725





5765
AAGUUAGG G UCUAUGUA
8066
UACAUAGA GCCGAAAGGCGAGUGAGGUCU CCUAACUU
18726





5771
GGGUCUAU G UAUUUAGG
8067
CCUAAAUA GCCGAAAGGCGAGUGAGGUCU AUAGACCC
18727





5782
UUUAGGAU G CGCCUACU
8069
AGUAGGCG GCCGAAAGGCGAGUGAGGUCU AUCCUAAA
18728





5784
UAGGAUGC G CCUACUCU
8070
AGAGUAGG GCCGAAAGGCGAGUGAGGUCU GCAUCCUA
18729





5798
UCUUCAGG G UCUAAAGA
8053
UCUUUAGA GCCGAAAGGCGAGUGAGGUCU CCUGAAGA
18716





5811
AAGAUCAA G UGGGCCUU
8055
AAGGCCCA GCCGAAAGGCGAGUGAGGUCU UUGAUCUU
18717





5815
UCAAGUGG G CCUUGGAU
8056
AUCCAAGG GCCGAAAGGCGAGUGAGGUCU CCACUUGA
18718





5825
CUUGGAUC G CUAAGCUG
8058
CAGCUUAG GCCGAAAGGCGAGUGAGGUCU GAUCCAAG
18719





5830
AUCGCUAA G CUGGCUCU
8059
AGAGCCAG GCCGAAAGGCGAGUGAGGUCU UUAGCGAU
18720





5834
CUAAGCUG G CUCUGUUU
8060
AAACAGAG GCCGAAAGGCGAGUGAGGUCU CAGCUUAG
18721





5839
CUGGCUCU G UUUGAUGC
8061
GCAUCAAA GCCGAAAGGCGAGUGAGGUCU AGAGCCAG
18722





5846
UGUUUGAU G CUAUUUAU
8063
AUAAAUAG GCCGAAAGGCGAGUGAGGUCU AUCAAACA
18723





5855
CUAUUUAU G CAAGUUAG
8064
CUAACUUG GCCGAAAGGCGAGUGAGGUCU AUAAAUAG
18724





5859
UUAUGCAA G UUAGGGUC
8065
GACCCUAA GCCGAAAGGCGAGUGAGGUCU UUGCAUAA
18725





5865
AAGUUAGG G UCUAUGUA
8066
UACAUAGA GCCGAAAGGCGAGUGAGGUCU CCUAACUU
18726





5871
GGGUCUAU G UAUUUAGG
8067
CCUAAAUA GCCGAAAGGCGAGUGAGGUCU AUAGACCC
18727





5882
UUUAGGAU G UCUGCACC
8072
GGUGCAGA GCCGAAAGGCGAGUGAGGUCU AUCCUAAA
18730





5886
GGAUGUCU G CACCUUCU
8073
AGAAGGUG GCCGAAAGGCGACUGAGGUCU AGACAUCC
18731





5895
CACCUUCU G CAGCCAGU
8074
ACUGGCUG GCCGAAAGGCGAGUGAGGUCU AGAAGGUG
18732





5898
CUUCUGCA G CCAGUCAG
8075
CUGACUGG GCCGAAAGGCGAGUGAGGUCU UGCAGAAG
18733





5902
UGCAGCCA G UCAGAAGC
8076
GCUUCUGA GCCGAAAGGCGAGUGAGGUCU UGGCUGCA
18734





5909
AGUCAGAA G CUGGAGAG
8077
CUCUCCAG GCCGAAAGGCGAGUGAGGUCU UUCUGACU
18735





5918
CUGGAGAG G CAACAGUG
8078
CACUGUUG GCCGAAAGGCGAGUGAGGUCU CUCUCCAG
18736





5924
AGGCAACA G UGGAUUGC
8080
GCAAUCCA GCCGAAAGGCGAGUGAGGUCU UGUUGCCU
18737





5931
AGUGGAUU G CUGCUUCU
8082
AGAAGCAG GCCGAAAGGCGAGUGAGGUCU AAUCCACU
18738





5934
GGAUUGCU G CUUCUUGG
8083
CCAAGAAG GCCGAAAGGCGAGUGAGGUCU AGCAAUCC
18739





5951
GGAGAAGA G UAUGCUUC
8084
GAAGCAUA GCCGAAAGGCGAGUGAGGUCU UCUUCUCC
18740





5955
AAGAGUAU G CUUCCUUU
8085
AAAGGAAG GCCGAAAGGCGAGUGAGGUCU AUACUCUU
18741





5971
UUAUCCAU G UAAUUUAA
8086
UUAAAUUA GCCGAAAGGCGAGUGAGGUCU AUGGAUAA
18742





5982
AUUUAACU G UAGAACCU
8089
AGGUUCUA GCCGAAAGGCGAGUGAGGUCU AGUUAAAU
18743





5993
GAACCUGA G CUCUAAGU
8091
ACUUAGAG GCCGAAAGGCGAGUGAGGUCU UCAGGUUC
18744





6000
AGCUCUAA G UAACCGAA
8092
UUCGGUUA GCCGAAAGGCGAGUGAGGUCU UUAGAGCU
18745





6013
CGAAGAAU G UAUGCCUC
8095
GAGGCAUA GCCGAAAGGCGAGUGAGGUCU AUUCUUCG
18746





6017
GAAUGUAU G CCUCUGUU
8096
AACAGAGG GCCGAAAGGCGAGUGAGGUCU AUACAUUC
18747





6023
AUGCCUCU G UUCUUAUG
8097
CAUAAGAA GCCGAAAGGCGAGUGAGGUCU AGAGGCAU
18748





6031
GUUCUUAU G UGCCACAU
8098
AUGUGGCA GCCGAAAGGCGAGUGAGGUCU AUAAGAAC
18749





6033
UCUUAUGU G CCACAUCC
8099
GGAUGUGG GCCGAAAGGCGAGUGAGGUCU ACAUAAGA
18750





6044
ACAUCCUU G UUUAAAGG
8100
CCUUUAAA GCCGAAAGGCGAGUGAGGUCU AAGGAUGU
18751





6052
GUUUAAAG G CUCUCUGU
8101
ACAGAGAG GCCGAAAGGCGAGUGAGGUCU CUUUAAAC
18752





6059
GGCUCUCU G UAUGAAGA
8102
UCUUCAUA GCCGAAAGGCGAGUGAGGUCU AGAGAGCC
18753





6077
AUGGGACC G UCAUCAGC
8105
GCUGAUGA GCCGAAAGGCGAGUGAGGUCU GGUCCCAU
18754





6084
CGUCAUCA G CACAUUCC
8106
GGAAUGUG GCCGAAAGGCGAGUGAGGUCU UGAUGACG
18755





6096
AUUCCCUA G UGAGCCUA
8107
UAGGCUCA GCCGAAAGGCGAGUGAGGUCU UAGGGAAU
18756





6100
CCUAGUGA G CCUACUGG
8108
CCAGUAGG GCCGAAAGGCGAGUGAGGUCU UCACUAGG
18757





6108
GCCUACUG G CUCCUGGC
8109
GCCAGGAG GCCGAAAGGCGAGUGAGGUCU CAGUAGGC
18758





6115
GGCUCCUG G CAGCGGCU
8110
AGCCGCUG GCCGAAAGGCGAGUGAGGUCU CAGGAGCC
18759





6118
UCCUGGCA G CGGCUUUU
8111
AAAAGCCG GCCGAAAGGCGAGUGAGGUCU UGCCAGGA
18760





6121
UGGCAGCG G CUUUUGUG
8112
CACAAAAG GCCGAAAGGCGAGUGAGGUCU CGCUGCCA
18761





6127
CGGCUUUU G UGGAAGAC
8113
GUCUUCCA GCCGAAAGGCGAGUGAGGUCU AAAAGCCG
18762





6142
ACUCACUA G CCAGAAGA
8115
UCUUCUGG GCCGAAAGGCGAGUGAGGUCU UAGUGAGU
18763





6156
AGAGAGGA G UGGGACAG
8116
CUGUCCCA GCCGAAAGGCGAGUGAGGUCU UCCUCUCU
18764





6164
GUGGGACA G UCCUCUCC
8118
GGAGAGGA GCCGAAAGGCGAGUGAGGUCU UGUCCCAC
18765





6197
AAACAAAA G CAGGCUAG
8122
CUAGCCUG GCCGAAAGGCGAGUGAGGUCU UUUUGUUU
18766





6201
AAAAGCAG G CUAGAGCC
8123
GGCUCUAG GCCGAAAGGCGAGUGAGGUCU CUGCUUUU
18767





6207
AGGCUAGA G CCAGAAGA
8124
UCUUCUGG GCCGAAAGGCGAGUGAGGUCU UCUAGCCU
18768





6230
AAAUCUUU G UUGUUCCU
8127
AGGAACAA GCCGAAAGGCGAGUGAGGUCU AAAGAUUU
18769





6233
UCUUUGUU G UUCCUCUU
8128
AAGAGGAA GCCGAAAGGCGAGUGAGGUCU AACAAAGA
18770





6254
ACACAUAC G CAAACCAC
8129
GUGGUUUG GCCGAAAGGCGAGUGAGGUCU GUAUGUGU
18771





6265
AACCACCU G UGACAGCU
8131
AGCUGUCA GCCGAAAGGCGAGUGAGGUCU AGGUGGUU
18772





6271
CUGUGACA G CUGGCAAU
8133
AUUGCCAG GCCGAAAGGCGAGUGAGGUCU UGUCACAG
18773





6275
GACAGCUG G CAAUUUUA
8134
UAAAAUUG GCCGAAAGGCGAGUGAGGUCU CAGCUGUC
18774





6292
UAAAUCAG G UAACUGGA
8137
UCCAGUUA GCCGAAAGGCGAGUGAGGUCU CUGAUUUA
18775





6306
GGAAGGAG G UUAAACUC
8139
GAGUUUAA GCCGAAAGGCGAGUGAGGUCU CUCCUUCC
18776





6333
AGACCUCA G UCAAUUCU
8142
AGAAUUGA GCCGAAAGGCGAGUGAGGUCU UGAGGUCU
18777





6377
AGAUAAUA G CCCAGCAA
8147
UUGCUGGG GCCGAAAGGCGAGUGAGGUCU UAUUAUCU
18778





6382
AUAGCCCA G CAAAUAGU
8148
ACUAUUUG GCCGAAAGGCGAGUGAGGUCU UGGGCUAU
18779





6389
AGCAAAUA G UGAUAACA
8150
UGUUAUCA GCCGAAAGGCGAGUGAGGUCU UAUUUGCU
18780





6410
AAACCUUA G CUGUUCAU
8155
AUGAACAG GCCGAAAGGCGAGUGAGGUCU UAAGGUUU
18781





6413
CCUUAGCU G UUCAUGUC
8156
GACAUGAA GCCGAAAGGCGAGUGAGGUCU AGCUAAGG
18782





6419
CUGUUCAU G UCUUGAUU
8157
AAUCAAGA GCCGAAAGGCGAGUGAGGUCU AUGAACAG
18783





6487
AGAGAAAA G CAAAACCA
8166
UGGUUUUG GCCGAAAGGCGAGUGAGGUCU UUUUCUCU
18784





6504
UUAGAAUU G UUACUCAG
8169
CUGAGUAA GCCGAAAGGCGAGUGAGGUCU AAUUCUAA
18785





6512
GUUACUCA G CUCCUUCA
8170
UGAAGGAG GCCGAAAGGCGAGUGAGGUCU UGAGUAAC
18786





6528
AAACUCAG G UUUGUAGC
8172
GCUACAAA GCCGAAAGGCGAGUGAGGUCU CUGAGUUU
18787





6532
UCAGGUUU G UAGCAUAC
8173
GUAUGCUA GCCGAAAGGCGAGUGAGGUCU AAACCUGA
18788





6535
GGUUUGUA G CAUACAUG
8174
CAUGUAUG GCCGAAAGGCGAGUGAGGUCU UACAAACC
18789





6545
AUACAUGA G UCCAUCCA
8175
UGGAUGGA GCCGAAAGGCGAGUGAGGUCU UCAUGUAU
18790





6557
AUCCAUCA G UCAAAGAA
8176
UUCUUUGA GCCGAAAGGCGAGUGAGGUCU UGAUGGAU
18791





6568
AAAGAAUG G UUCCAUCU
8178
AGAUGGAA GCCGAAAGGCGAGUGAGGUCU CAUUCUUU
18792





6580
CAUCUGGA G UCUUAAUG
8179
CAUUAAGA GCCGAAAGGCGAGUGAGGUCU UCCAGAUG
18793





6588
GUCUUAAU G UAGAAAGA
8181
UCUUUCUA GCCGAAAGGCGAGUGAGGUCU AUUAAGAC
18794





6610
GGAGACUU G UAAUAAUG
8184
CAUUAUUA GCCGAAAGGCGAGUGAGGUCU AAGUCUCC
18795





6620
AAUAAUGA G CUAGUCAC
8187
GUAACUAG GCCGAAAGGCGAGUGAGGUCU UCAUUAUU
18796





6624
AUGAGCUA G UUACAAAG
8188
CUUUGUAA GCCGAAAGGCGAGUGAGGUCU UAGCUCAU
18797





6632
GUUACAAA G UGCUUGUU
8189
AACAAGCA GCCGAAAGGCGAGUGAGGUCU UUUGUAAC
18798





6634
UACAAAGU G CUUGUUCA
8190
UGAACAAG GCCGAAAGGCGAGUGAGGUCU ACUUUGUA
18799





6638
AAGUGCUU G UUCAUUAA
8191
UUAAUGAA GCCGAAAGGCGAGUGAGGUCU AAGCACUU
18800





6651
UUAAAAUA G CACUGAAA
8193
UUUCAGUG GCCGAAAGGCGAGUGAGGUCU UAUUUUAA
18801





6698
AAUCAUUU G CCAUUUAU
8201
AUAAAUGG GCCGAAAGGCGAGUGAGGUCU AAAUGAUU
18802





6717
CAAAAAUG G UUGGCACU
8204
AGUGCCAA GCCGAAAGGCGAGUGAGGUCU CAUCUUUG
18803





6721
AAUGGUUG G CACUAACA
8205
UGUUAGUG GCCGAAAGGCGAGUGAGGUCU CAACCAUU
18804





6738
AAGAACGA G CACUUCCU
8208
AGGAAGUG GCCGAAAGGCGAGUGAGGUCU UCGUUCUU
18805





6753
CUUUCAGA G UCUCUGAG
8209
CUCAGAAA GCCGAAAGCCGAGUGAGGUCU UCUGAAAG
18806





6767
GAGAUAAU G UACGUGGA
8212
UCCACGUA GCCGAAAGGCGAGUGAGGUCU AUUAUCUC
18807





6771
UAAUGUAC G UGGAACAG
8213
CUGUUCCA GCCGAAAGGCGAGUGAGGUCU GUACAUUA
18808





6779
GUGGAACA G UCUGGGUG
8215
CACCCAGA GCCGAAAGGCGAGUGAGGUCU UGUUCCAC
18809





6785
CAGUCUGG G UGGAAUGG
8216
CCAUUCCA GCCGAAAGGCGAGUGAGGUCU CCAGACUG
18810





6795
GGAAUGGG G CUGAAACC
8218
GGUUUCAG GCCGAAAGGCGAGUGAGGUCU CCCAUUCC
18811





6806
GAAACCAU G UGCAAGUC
8220
GACUUGCA GCCGAAAGGCGAGUGAGGUCU AUGGUUUC
18812





6808
AACCAUGU G CAAGUCUG
8221
CAGACUUG GCCGAAAGGCGAGUGAGGUCU ACAUGGUU
18813





6812
AUGUGCAA G UCUGUGUC
8222
GACACAGA GCCGAAAGGCGAGUGAGGUCU UUGCACAU
18814





6816
GCAAGUCU G UGUCUUGU
8223
ACAAGACA GCCGAAAGGCGAGUGAGGUCU AGACUUGC
18815





6818
AAGUCUGU G UCUUGUCA
8224
UGACAAGA GCCGAAAGGCGAGUGAGGUCU ACAGACUU
18816





6823
UGUGUCUU G UCAGUCCA
8225
UGGACUGA GCCGAAAGGCGAGUGAGGUCU AAGACACA
18817





6827
UCUUGUCA G UCCAAGAA
8226
UUCUUGGA GCCGAAAGGCGAGUGAGGUCU UGACAAGA
18818





6836
UCCAAGAA G UGACACCG
8227
CGGUGUCA GCCGAAAGGCGAGUGAGGUCU UUCUUGGA
18819





6849
ACCGAGAU G UUAAUUUU
8230
AAAAUUAA GCCGAAAGGCGAGUGAGGUCU AUCUCGGU
18820





6866
AGGGACCC G UGCCUUGU
8233
ACAAGGCA GCCGAAAGGCGAGUGAGGUCU GGGUCCCU
18821





6868
GGACCCGU G CCUUGUUU
8234
AAACAAGG GCCGAAAGGCGAGUGAGGUCU ACGGGUCC
18822





6873
CGUGCCUU G UUUCCUAG
8235
CUAGGAAA GCCGAAAGGCGAGUGAGGUCU AAGGCACG
18823





6881
GUUUCCUA G CCCACAAG
8236
CUUGUGGG GCCGAAAGGCGAGUGAGGUCU UAGGAAAC
18824





6893
ACAAGAAU G CAAACAUC
8238
GAUGUUUG GCCGAAAGGCGAGUGAGGUCU AUUCUUGU
18825





6914
AGAUACUC G CUAGCCUC
8242
GAGGCUAG GCCGAAAGGCGAGUGAGGUCU CAGUAUCU
18826





6918
ACUCGCUA G CCUCAUUU
8243
AAAUGAGG GCCGAAAGGCGAGUGAGGUCU UAGCGAGU
18827





6945
AAGGAGGA G UGCAUCUU
8246
AAGAUGCA GCCGAAAGGCGAGUGAGGUCU UCCUCCUU
18828





6947
GGAGGAGU G CAUCUUUG
8247
CAAAGAUG GCCGAAAGGCGAGUGAGGUCU ACUCCUCC
18829





6956
CAUCUUUG G CCGACAGU
8248
ACUGUCGG GCCGAAAGGCGAGUGAGGUCU CAAAGAUG
18830





6963
GGCCGACA G UGGUGUAA
8250
UUACACCA GCCGAAAGGCGAGUGAGGUCU UGUCGGCC
18831





6966
CGACAGUG G UGUAACUG
8251
CAGUUACA GCCGAAAGGCGAGUGAGGUCU CACUGUCG
18832





6968
ACAGUGGU G UAACUGUG
8252
CACAGUUA GCCGAAAGGCGAGUGAGGUCU ACCACUGU
18833





6974
GUGUAACU G UGUGUGUG
8254
CACACACA GCCGAAAGGCGAGUGAGGUCU AGUUACAC
18834





6976
GUAACUGU G UGUGUGUG
8255
CACACACA GCCGAAAGGCGAGUGAGGUCU ACAGUUAC
18835





6978
AACUGUGU G UGUGUGUG
8256
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACAGUU
18836





6980
CUGUGUGU G UGUGUGUG
8257
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAG
18837





6982
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6984
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6986
GUGUGUGU G UGUCUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6988
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6990
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6992
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6994
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6996
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





6998
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





7000
GUCUGUGU G UGUGUGUC
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





7002
GUGUGUGU G UGUGUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





7004
GUGUGUGU G UGUCUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGCUCU ACACACAC
18838





7006
GUGUGUGU G UGUCUGUG
8258
CACACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18838





7008
GUGUGUGU G UGUGUGGG
8259
CCCACACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18839





7010
GUGUGUGU G UGUGGGUG
8260
CACCCACA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18840





7012
GUGUGUGU G UGGGUGUG
8261
CACACCCA GCCGAAAGGCGAGUGAGGUCU ACACACAC
18841





7016
GUGUGUGG G UGUGGGUG
8262
CACCCACA GCCGAAAGGCGAGUGAGGUCU CCACACAC
18842





7018
GUGUGGGU G UGGGUGUA
8263
UACACCCA GCCGAAAGGCGAGUGAGGUCU ACCCACAC
18843





7022
GGGUGUGG G UGUAUGUG
8264
CACAUACA GCCGAAAGGCGAGUGAGGUCU CCACACCC
18844





7024
GUGUGGGU G UAUGUGUG
8265
CACACAUA GCCGAAAGGCGAGUGAGGUCU ACCCACAC
18845





7028
GGGUGUAU G UGUGUUUU
8266
AAAACACA GCCGAAAGGCGAGUGAGGUCU AUACACCC
18846





7030
GUGUAUGU G UGUUUUGU
8267
ACAAAACA GCCGAAAGGCGAGUGAGGUCU ACAUACAC
18847





7032
GUAUGUGU G UUUUGUGC
8268
GCACAAAA GCCGAAAGGCGAGUGAGGUCU ACACAUAC
18848





7037
UGUGUUUU G UGCAUAAC
8269
GUUAUGCA GCCGAAAGGCGAGUGAGGUCU AAAACACA
18849





7039
UGUUUUGU G CAUAACUA
8270
UAGUUAUG GCCGAAAGGCGAGUGAGGUCU ACAAAACA
18850





7071
AUUUUAAA G UUACUUUU
8274
AAAAGUAA GCCGAAAGGCGAGUGAGGUCU UUUAAAAU
18851





7099
GAAUAUAU G CUACAGAU
8277
AUCUGUAG GCCGAAAGGCGAGUGAGGUCU AUAUAUUC
18852





7122
CAGACAUG G UUUGGUCC
8281
GGACCAAA GCCGAAAGGCGAGUGAGGUCU CAUGUCUG
18853





7127
AUGGUUUG G UCCUAUAU
8282
AUAUAGGA GCCGAAAGGCGAGUGAGGUCU CAAACCAU
18854





7141
UAUUUCUA G UCAUGAUG
8283
CAUCAUGA GCCGAAAGGCGAGUGAGGUCU UAGAAAUA
18855





7153
UGAUGAAU G UAUUUUGU
8286
ACAAAAUA GCCGAAAGGCGAGUGAGGUCU AUUCAUCA
18856





7160
UGUAUUUU G UAUACCAU
8287
AUGGUAUA GCCGAAAGGCGAGUGAGGUCU AAAAUACA
18857





7210
UGGGAUUU G UAAUCGUA
8292
UACGAUUA GCCGAAAGGCGAGUGAGGUCU AAAUCCCA
18858





7216
UUGUAAUC G UACCAACU
8294
AGUUGGUA GCCGAAAGGCGAGUGAGGUCU GAUUACAA
18859





7240
UAAACUUG G CAACUGCU
8299
AGCAGUUG GCCGAAAGGCGAGUGAGGUCU CAAGUUUA
18860





7246
UGGCAACU G CUUUUAUG
8301
CAUAAAAG GCCGAAAGGCGAGUGAGGUCU AGUUGCCA
18861





7254
GCUUUUAU G UUCUGUCU
8302
AGACAGAA GCCGAAAGGCGAGUGAGGUCU AUAAAAGC
18862





7259
UAUGUUCU G UCUCCUUC
8303
GAAGGAGA GCCGAAAGGCGAGUGAGGUCU AGAACAUA
18863





7305
AAGAAAAA G CUCUUUUU
8308
AAAAAGAG GCCGAAAGGCGAGUGAGGUCU UUUUUCUU
18864





7343
UUAUCCUU G UUUAGAGC
8312
GCUCUAAA GCCGAAAGGCGAGUGAGGUCU AAGGAUAA
18865





7350
UGUUUAGA G CAGAGAAA
8313
UUUCUCUG GCCGAAAGGCGAGUGAGGUCU UCUAAACA
18866





7381
UUGAAAUG G UCUCAAAA
8317
UUUUGAGA GCCGAAAGGCGAGUGAGGUCU CAUUUCAA
18867





7394
AAAAAAUU G CUAAAUAU
8319
AUAUUUAG GCCGAAAGGCGAGUGAGGUCU AAUUUUUU
18868





7422
AACUAAAU G UUAGUUUA
8324
UAAACUAA GCCGAAAGGCGAGUGAGGUCU AUUUAGUU
18869





7426
AAAUGUUA G UUUAGCUG
8325
CAGCUAAA GCCGAAAGGCGAGUGAGGUCU UAACAUUU
18870





7431
UUAGUUUA G CUGAUUGU
8326
ACAAUCAG GCCGAAAGGCGAGUGAGGUCU UAAACUAA
18871





7438
AGCUGAUU G UAUGGGGU
8328
ACCCCAUA GCCGAAAGGCGAGUGAGGUCU AAUCAGCU
18872





7445
UGUAUGGG G UUUUCGAA
8329
UUCGAAAA GCCGAAAGGCGAGUGAGGUCU CCCAUACA
18873





7467
CACUUUUU G UUUGUUUU
8331
AAAACAAA GCCGAAAGGCGAGUGAGGUCU AAAAAGUG
18874





7471
UUUUGUUU G UUUUACCU
8332
AGGUAAAA GCCGAAAGGCGAGUGAGGUGU AAACAAAA
18875





7491
UCACAACU G UGUAAAUU
8334
AAUUUACA GCCGAAAGGCGAGUGAGGUCU AGUUGUGA
18876





7493
ACAACUGU G UAAAUUGC
8335
GCAAUUUA GCCGAAAGGCGAGUGAGGUCU ACAGUUGU
18877





7500
UGUAAAUU G CCAAUAAU
8337
AUUAUUGG GCCGAAAGGCGAGUGAGGUCU AAUUUACA
18878





7513
UAAUUCCU G UCCAUGAA
8340
UUCAUGGA GCCGAAAGGCGAGUGAGGUCU AGGAAUUA
18879





7525
AUGAAAAU G CAAAUUAU
8342
AUAAUUUG GCCGAAAGGCGAGUGAGGUCU AUUUUCAU
18880





7537
AUUAUCCA G UGUAGAUA
8344
UAUCUACA GCCGAAAGGCGAGUGAGGUCU UGGAUAAU
18881





7539
UAUCCAGU G UAGAUAUA
8345
UAUAUCUA GCCGAAAGGCGAGUGAGGUCU ACUGGAUA
18882





7573
GGAUAUUG G CUAGUUUU
8349
AAAACUAG GCCGAAAGGCGAGUGAGGUCU CAAUAUCC
18883





7577
AUUGGCUA G UUUUGCCU
8350
AGGCAAAA GCCGAAAGGCGAGUGAGGUCU UAGCCAAU
18884





7582
CUAGUUUU G CCUUUAUU
8351
AAUAAAGG GCCGAAAGGCGAGUGAGGUCU AAAACUAG
18885





7593
UUUAUUAA G CAAAUUCA
8352
UGAAUUUG GCCGAAAGGCGAGUGAGGUCU UUAAUAAA
18886





7607
UCAUUUCA G CCUGAAUG
8354
CAUUCAGG GCCGAAAGGCGAGUGAGGUCU UGAAAUGA
18887





7615
GCCUGAAU G UCUGCCUA
8356
UAGGCAGA GCCGAAAGGCGAGUGAGGUCU AUUCAGGC
18888





7619
GAAUGUCU G CCUAUAUA
8357
UAUAUAGG GCCGAAAGGCGAGUGAGGUCU AGACAGUC
18889





7634
UAUUCUCU G CUCUUUGU
8358
ACAAAGAG GCCGAAAGGCGAGUGAGGUCU AGAGAAUA
18890





7641
UGCUCUUU G UAUUCUCC
8359
GGAGAAUA GCCGAAAGGCGAGUGAGGUCU AAAGAGCA
18891





7659
UUGAACCC G UUAAAACA
8361
UGUUUUAA GCCGAAAGGCGAGUGAGGUCU GGGUUCAA
18892





7672
AACAUCCU G UGGCACUC
8363
GAGUGCCA GCCGAAAGGCGAGUGAGGUCU AGGAUGUU
18893






Input Sequence = HSFLT. Cut Site = G/Y




Arm Length = 8. Core Sequence = GCcgaaagGCGaGuCaaGGuCu




HSFLT (Human flt mRNA for receptor-related tyrosine kinase; Acc# X51602; 7680 bp)








[0359]

23





TABLE XX










Patient Demographics













Dose








cohort


(mg/m2)
Pt#
Age
Sex
Diagnosis
Status
Doses
















10
1001
49
F
NSC Lung
PD
29


10
1002
65
F
liposarcoma
PD
120 


10
1003
49
M
nasopharyngeal CA
WD
109 


30
1004*


30
1005
45
F
melanoma (ocular)
PD
113 


30
1006
57
M
colon
PD
199 


30
1007
39
F
epitheliod
PD
198 






hemangioendo-






thelioma


100
1008
52
M
adrenal ca
PD
57


100
1009
44
F
breast
PD
35


100
1010
62
F
renal
PD
134 


300
1011
24
F
melanoma
PD
31


300
1012
57
M
renal cell
PD
178 


300
1013
53
M
nasopharyngeal
PD
29






SCCA


300
1014
64
F
peritoneal
stable
 236**






mesothelioma


100
1015
65
M
melanoma
PD
140 


100
1016
77
F
breast
stable
 231**


100
1017

F
melanoma
PD
35


100
1018*


100
1019
69
F
endometrial sarcoma
stable
 212**


100
1020
65
M
carcinoid
PD
124 


100
1021
59
M
gallbladder adeno
PD
34






carcinoma


100
1022*


100
1023
78
F
breast
PD
50


100
1024
40
F
parotid
stable
 161**






adenocarcinoma


100
1025
52
F
breast
WD
71


100
1026
39
F
breast
PD
34


100
1027
55
F
breast
PD
36


100
1028
52
M
melanoma
PD
29


100
1029
38
M
pancreatic
PD
36


100
1030
83
M
melanoma
PD
41


100
1031
50
M
medullary thyroid
WD
108 






PD = progressive disease; WD = withdrawal. 4 patients remain on study.




*Inappropriate enrollment, patient withdrawn




**As of Jan. 11, 2000








[0360]

24





TABLE XXI










Pharmacokinetic parameters of ANGIOZYME after bolus


subcutaneous administration.












10 mg/m2
30 mg/m2
100 mg/m2
300 mg/m2
















Mean
SD
Mean
SD
Mean
SD
Mean
SD



















Day 1










Cmax
0.43
0.07
0.62
0.28
3.17
0.69
8.91
2.93


(ug/mL)


AUCt
2.60
1.43
6.04
2.70
34.14
2.28
89.87
21.68


(ug*hr/mL)


AUCinf
4.40
0.06
7.99
1.66
37.51
1.91
101.57
13.47


(ug*hr/mL)


t(1/2) (hr)
3.62
0.79
7.32
6.94
4.58
0.02
9.26
6.20


CL/F
2.24
0.08
3.73
0.92
2.96
0.61
2.99
0.43


(L/hr/m2)


Day 29


Cmax
0.35
0.19
1.17
0.53
3.23
0.35
8.93
6.71


(ug/mL)


AUCt
2.11
1.31
7.29
1.16
31.87
1.91
119.42
65.84


(ug*hr/mL)


AUCinf
3.38
1.31
8.54
2.46
33.61
2.16
132.73
67.82


(ug*hr/mL)


t(1/2) (hr)
4.49
1.60
3.26
1.01
4.66
0.35
7.24
0.70


CL/F
2.49
1.48
3.69
0.94
3.21
0.56
2.72
1.40


(L/hr/m2)










[0361]

25





TABLE XXII










Human KDR DNAzyme and Substrate sequence













Seq ID

Seq ID


Pos
Substrate
No
DNAzyme
No














14
GUCCCGGG A CCCCGGGA
8364
TCCCGGGG GGCTAGCTACAACGA CCCGGGAC
18894





25
CCGGGAGA G CGGUCAGU
8365
ACTGACCG GGCTAGCTACAACGA TCTCCCGG
18895





28
GGAGAGCG G UCAGUGUG
8366
CACACTGA GGCTAGCTACAACGA CGCTCTCC
18896





32
AGCGGUCA G UGUGUGGU
8367
ACCACACA GGCTAGCTACAACGA TGACCGCT
18897





34
CGGUCAGU G UGUGGUCG
8368
CGACCACA GGCTAGCTACAACGA ACTGACCG
18898





36
GUCAGUGU G UGGUCGCU
8369
AGCGACCA GGCTAGCTACAACGA ACACTGAC
18899





39
AGUGUGUG G UCGCUGCG
8370
CGCAGCGA GGCTAGCTACAACGA CACACACT
18900





42
GUGUGGUC G CUGCGUUU
8371
AAACGCAG GGCTAGCTACAACGA GACCACAC
18901





45
UGGUCGCU G CGUUUCCU
8372
AGGAAACG GGCTAGCTACAACGA AGCGACCA
18902





47
GUCGCUGC G UUUCCUCU
8373
AGAGGAAA GGCTAGCTACAACGA GCAGCGAC
18903





56
UUUCCUCU G CCUGCGCC
8374
GGCGCAGG GGCTAGCTACAACGA AGAGGAAA
18904





60
CUCUGCCU G CGCCGGGC
8375
GCCCGGCG GGCTAGCTACAACGA AGGCAGAG
18905





62
CUGCCUGC G CCGGGCAU
8376
ATGCCCGG GGCTAGCTACAACGA GCAGGCAG
18906





67
UGCGCCGG G CAUCACUU
8377
AAGTGATG GGCTAGCTACAACGA CCGGCGCA
18907





69
CGCCGGGC A UCACUUGC
8378
GCAAGTGA GGCTAGCTACAACGA GCCCGGCG
18908





72
CGGGCAUC A CUUGCGCG
8379
CGCGCAAG GGCTAGCTACAACGA GATGCCCG
18909





76
CAUCACUU G CGCGCCGC
8380
GCGGCGCG GGCTAGCTACAACGA AAGTGATG
18910





78
UCACUUGC G CGCCGCAG
8381
CTGCGGCG GGCTAGCTACAACGA GCAAGTGA
18911





80
ACUUGCGC G CCGCAGAA
8382
TTCTGCGG GGCTAGCTACAACGA GCGCAAGT
18912





83
UGCGCGCC G CAGAAAGU
8383
ACTTTCTG GGCTAGCTACAACGA GGCGCGCA
18913





90
CGCAGAAA G UCCGUCUG
8384
CAGACGGA GGCTAGCTACAACGA TTTCTGCG
18914





94
GAAAGUCC G UCUGGCAG
8385
CTGCCAGA GGCTAGCTACAACGA GGACTTTC
18915





99
UCCGUCUG G CAGCCUGG
8386
CCAGGCTG GGCTAGCTACAACGA CAGACGGA
18916





102
GUCUGGCA G CCUGGAUA
8387
TATCCAGG GGCTAGCTACAACGA TGCCAGAC
18917





108
CAGCCUGG A UAUCCUCU
8388
AGAGGATA GGCTAGCTACAACGA CCAGGCTG
18918





110
GCCUGGAU A UCCUCUCC
8389
GGAGAGGA GGCTAGCTACAACGA ATCCAGGC
18919





120
CCUCUCCU A CCGGCACC
8390
GGTGCCGG GGCTAGCTACAACGA AGGAGAGG
18920





124
UCCUACCG G CACCCGCA
8391
TGCGGGTG GGCTAGCTACAACGA CGGTAGGA
18921





126
CUACCGGC A CCCGCAGA
8392
TCTGCGGG GGCTAGCTACAACGA GCCGGTAG
18922





130
CGGCACCC G CAGACGCC
8393
GGCGTCTG GGCTAGCTACAACGA GGGTGCCG
18923





134
ACCCGCAG A CGCCCCUG
8394
CAGGGGCG GGCTAGCTACAACGA CTGCGGGT
18924





136
CCGCAGAC G CCCCUGCA
8395
TGCAGGGG GGCTAGCTACAACGA GTCTGCGG
18925





142
ACGCCCCU G CAGCCGCC
8396
GGCGGCTG GGCTAGCTACAACGA AGGGGCGT
18926





145
CCCCUGCA G CCGCCGGU
8397
ACCGGCGG GGCTAGCTACAACGA TGCAGGGG
18927





148
CUGCAGCC G CCGGUCGG
8398
CCGACCGG GGCTAGCTACAACGA GGCTGCAG
18928





152
AGCCGCCG G UCGGCGCC
8399
GGCGCCGA GGCTAGCTACAACGA CGGCGGCT
18929





156
GCCGGUCG G CGCCCGGG
8400
CCCGGGCG GGCTAGCTACAACGA CGACCGGC
18930





158
CGGUCGGC G CCCGGGCU
8401
AGCCCGGG GGCTAGCTACAACGA GCCGACCG
18931





164
GCGCCCGG G CUCCCUAG
8402
CTAGGGAG GGCTAGCTACAACGA CCGGGCGC
18932





172
GCUCCCUA G CCCUGUGC
8403
GCACAGGG GGCTAGCTACAACGA TAGGGAGC
18933





177
CUAGCCCU G UGCGCUCA
8404
TGAGCGCA GGCTAGCTACAACGA AGGGCTAG
18934





179
AGCCCUGU G CGCUCAAC
8405
GTTGAGCG GGCTAGCTACAACGA ACAGGGCT
18935





181
CCCUGUGC G CUCAACUG
8406
CAGTTGAG GGCTAGCTACAACGA GCACAGGG
18936





186
UGCGCUCA A CUGUCCUG
8407
CAGGACAG GGCTAGCTACAACGA TGAGCGCA
18937





189
GCUCAACU G UCCUGCGC
8408
GCGCAGGA GGCTAGCTACAACGA AGTTGAGC
18938





194
ACUGUCCU G CGCUGCGG
8409
CCGCAGCG GGCTAGCTACAACGA AGGACAGT
18939





196
UGUCCUGC G CUGCGGGG
8410
CCCCGCAG GGCTAGCTACAACGA GCAGGACA
18940





199
CCUGCGCU G CGGGGUGC
8411
GCACCCCG GGCTAGCTACAACGA AGCGCAGG
18941





204
GCUGCGGG G UGCCGCGA
8412
TCGCGGCA GGCTAGCTACAACGA CCCGCAGC
18942





206
UGCGGGGU G CCGCGAGU
8413
ACTCGCGG GGCTAGCTACAACGA ACCCCGCA
18943





209
GGGGUGCC G CGAGUUCC
8414
GGAACTCG GGCTAGCTACAACGA GGCACCCC
18944





213
UGCCGCGA G UUCCACCU
8415
AGGTGGAA GGCTAGCTACAACGA TCGCGGCA
18945





218
CGAGUUCC A CCUCCGCG
8416
CGCGGAGG GGCTAGCTACAACGA GGAACTCG
18946





224
CCACCUCC G CGCCUCCU
8417
AGGAGGCG GGCTAGCTACAACGA GGAGGTGG
18947





226
ACCUCCGC G CCUCCUUC
8418
GAAGGAGG GGCTAGCTACAACGA GCGGAGGT
18948





240
UUCUCUAG A CAGGCGCU
8419
AGCGCCTG GGCTAGCTACAACGA CTAGAGAA
18949





244
CUAGACAG G CGCUGGGA
8420
TCCCAGCG GGCTAGCTACAACGA CTGTCTAG
18950





246
AGACAGGC G CUGGGAGA
8421
TCTCCCAG GGCTAGCTACAACGA GCCTGTCT
18951





259
GAGAAAGA A CCGGCUCC
8422
GGAGCCGG GGCTAGCTACAACGA TCTTTCTC
18952





263
AAGAACCG G CUCCCGAG
8423
CTCGGGAG GGCTAGCTACAACGA CGGTTCTT
18953





271
GCUCCCGA G UUCUGGGC
8424
GCCCAGAA GGCTAGCTACAACGA TCGGGAGC
18954





278
AGUUCUGG G CAUUUCGC
8425
GCGAAATG GGCTAGCTACAACGA CCAGAACT
18955





280
UUCUGGGC A UUUCGCCC
8426
GGGCGAAA GGCTAGCTACAACGA GCCCAGAA
18956





285
GGCAUUUC G CCCGGCUC
8427
GAGCCGGG GGCTAGCTACAACGA GAAATGCC
18957





290
UUCGCCCG G CUCGAGGU
8428
ACCTCGAG GGCTAGCTACAACGA CGGGCGAA
18958





297
GGCUCGAG G UGCAGGAU
8429
ATCCTGCA GGCTAGCTACAACGA CTCGAGCC
18959





299
CUCGAGGU G CAGGAUGC
8430
GCATCCTG GGCTAGCTACAACGA ACCTCGAG
18960





304
GGUGCAGG A UGCAGAGC
8431
GCTCTGCA GGCTAGCTACAACGA CCTGCACC
18961





306
UGCAGGAU G CAGAGCAA
8432
TTGCTCTG GGCTAGCTACAACGA ATCCTGCA
18962





311
GAUGCAGA G CAAGGUGC
8433
GCACCTTG GGCTAGCTACAACGA TCTGCATC
18963





316
AGAGCAAG G UGCUGCUG
8434
CAGCAGCA GGCTAGCTACAACGA CTTGCTCT
18964





318
AGCAAGGU G CUGCUGGC
8435
GCCAGCAG GGCTAGCTACAACGA ACCTTGCT
18965





321
AAGGUGCU G CUGGCCGU
8436
ACGGCCAG GGCTAGCTACAACGA AGCACCTT
18966





325
UGCUGCUG G CCGUCGCC
8437
GGCGACGG GGCTAGCTACAACGA CAGCAGCA
18967





328
UGCUGGCC G UCGCCCUG
8438
CAGGGCGA GGCTAGCTACAACGA GGCCAGCA
18968





331
UGGCCGUC G CCCUGUGG
8439
CCACAGGG GGCTAGCTACAACGA GACGGCCA
18969





336
GUCGCCCU G UGGCUCUG
8440
CAGAGCCA GGCTAGCTACAACGA AGGGCGAC
18970





339
GCCCUGUG G CUCUGCGU
8441
ACGCAGAG GGCTAGCTACAACGA CACAGGGC
18971





344
GUGGCUCU G CGUGGAGA
8442
TCTCCACG GGCTAGCTACAACGA AGAGCCAC
18972





346
GGCUCUGC G UGGAGACC
8443
GGTCTCCA GGCTAGCTACAACGA GCAGAGCC
18973





352
GCGUGGAG A CCCGGGCC
8444
GGCCCGGG GGCTAGCTACAACGA CTCCACGC
18974





358
AGACCCGG G CCGCCUCU
8445
AGAGGCGG GGCTAGCTACAACGA CCGGGTCT
18975





361
CCCGGGCC G CCUCUGUG
8446
CACAGAGG GGCTAGCTACAACGA GGCCCGGG
18976





367
CCGCCUCU G UGGGUUUG
8447
CAAACCCA GGCTAGCTACAACGA AGAGGCGG
18977





371
CUCUGUGG G UUUGCCUA
8448
TAGGCAAA GGCTAGCTACAACGA CCACAGAG
18978





375
GUGGGUUU G CCUAGUGU
8449
ACACTAGG GGCTAGCTACAACGA AAACCCAC
18979





380
UUUGCCUA G UGUUUCUC
8450
GAGAAACA GGCTAGCTACAACGA TAGGCAAA
18980





382
UGCCUAGU G UUUCUCUU
8451
AAGAGAAA GGCTAGCTACAACGA ACTAGGCA
18981





392
UUCUCUUG A UCUGCCCA
8452
TGGGCAGA GGCTAGCTACAACGA CAAGAGAA
18982





396
CUUGAUCU G CCCAGGCU
8453
AGCCTGGG GGCTAGCTACAACGA AGATCAAG
18983





402
CUGCCCAG G CUCAGCAU
8454
ATGCTGAG CCCTAGCTACAACGA CTGGGCAG
18984





407
CAGGCUCA G CAUACAAA
8455
TTTCTATG GGCTAGCTACAACGA TGAGCCTG
18985





409
GGCUCAGC A UACAAAAU
6138
TTTTTGTA GGCTAGCTACAACGA GCTGAGCC
18986





411
CUCAGCAU A CAAAAAGA
1519
TCTTTTTG GGCTAGCTACAACGA ATGCTGAG
18987





419
ACAAAAAG A CAUACUUA
8456
TAAGTATG GGCTAGCTACAACGA CTTTTTGT
18988





421
AAAAAGAC A UACUUACA
6140
TGTAAGTA GGCTAGCTACAACGA GTCTTTTT
18989





423
AAAGACAU A CUUACAAU
1520
ATTGTAAG GGCTAGCTACAACGA ATGTCTTT
18990





427
ACAUACUU A CAAUUAAG
1522
CTTAATTG GGCTAGCTACAACGA AAGTATGT
18991





430
UACUUACA A UUAAGGCU
8457
AGCCTTAA GGCTAGCTACAACGA TGTAAGTA
18992





436
CAAUUAAG G CUAAUACA
8458
TGTATTAG GGCTAGCTACAACGA CTTAATTG
18993





440
UAAGGCUA A UACAACUC
8459
GAGTTGTA GGCTAGCTACAACGA TAGCCTTA
18994





442
AGGCUAAU A CAACUCUU
1526
AAGAGTTG GGCTAGCTACAACGA ATTAGCCT
18995





445
CUAAUACA A CUCUUCAA
8460
TTGAAGAG GGCTAGCTACAACGA TGTATTAG
18996





454
CUCUUCAA A UUACUUGC
8461
GCAAGTAA GGCTAGCTACAACGA TTGAAGAG
18997





457
UUCAAAUU A CUUGCAGG
1531
CCTGCAAG GGCTAGCTACAACGA AATTTGAA
18998





461
AAUUACUU G CAGGGGAC
8462
GTCCCCTG GGCTAGCTACAACGA AAGTAATT
18999





468
UGCAGGGG A CAGAGGGA
8463
TCCCTCTG GGCTAGCTACAACGA CCCCTGCA
19000





476
ACAGAGGG A CUUGGACU
8464
AGTCCAAG GGCTAGCTACAACGA CCCTCTGT
19001





482
GGACUUGG A CUGGCUUU
8465
AAAGCCAG GGCTAGCTACAACGA CCAAGTCC
19002





486
UUGGACUG G CUUUGGCC
8466
GGCCAAAG GGCTAGCTACAACGA CAGTCCAA
19003





492
UGGCUUUG G CCCAAUAA
8467
TTATTGGG GGCTAGCTACAACGA CAAAGCCA
19004





497
UUGGCCCA A UAAUCAGA
8468
TCTGATTA GGCTAGCTACAACGA TGGGCCAA
19005





500
GCCCAAUA A UCAGAGUG
8469
CACTCTGA GGCTAGCTACAACGA TATTGGGC
19006





506
UAAUCAGA G UGGCAGUG
8470
CACTGCCA GGCTAGCTACAACGA TCTGATTA
19007





509
UCAGAGUG G CAGUGAGC
8471
GCTCACTG GGCTAGCTACAACGA CACTCTGA
19008





512
GAGUGGCA G UGAGCAAA
8472
TTTGCTCA GGCTAGCTACAACGA TGCCACTC
19009





516
GGCAGUGA G CAAAGGGU
8473
ACCCTTTG GGCTAGCTACAACGA TCACTGCC
19010





523
AGCAAAGG G UGGAGGUG
8474
CACCTCCA GGCTAGCTACAACGA CCTTTGCT
19011





529
GGGUGGAG G UGACUGAG
8475
CTCAGTCA GGCTAGCTACAACGA CTCCACCC
19012





532
UGGAGGUG A CUGAGUGC
8476
GCACTCAG GGCTAGCTACAACGA CACCTCCA
19013





537
GUGACUGA G UGCAGCGA
8477
TCGCTGCA GGCTAGCTACAACGA TCAGTCAC
19014





539
GACUGAGU G CAGCGAUG
8478
CATCGCTG GGCTAGCTACAACGA ACTCAGTC
19015





542
UGAGUGCA G CGAUGGCC
8479
GGCCATCG GGCTAGCTACAACGA TGCACTCA
19016





545
GUGCAGCG A UGGCCUCU
8480
AGAGGCCA GGCTAGCTACAACGA CGCTGCAC
19017





548
CAGCGAUG G CCUCUUCU
8481
AGAAGAGG GGCTAGCTACAACGA CATCGCTG
19018





557
CCUCUUCU G UAAGACAC
8482
GTGTCTTA GGCTAGCTACAACGA AGAAGAGG
19019





562
UCUGUAAG A CACUCACA
8483
TGTGAGTG GGCTAGCTACAACGA CTTACAGA
19020





564
UGUAAGAC A CUCACAAU
6166
ATTGTGAG GGCTAGCTACAACGA GTCTTACA
19021





568
AGACACUC A CAAUUCCA
6168
TGGAATTG GGCTAGCTACAACGA GAGTGTCT
19022





571
CACUCACA A UUCCAAAA
8484
TTTTGGAA GGCTAGCTACAACGA TGTGAGTG
19023





580
UUCCAAAA G UGAUCGGA
8485
TCCGATCA GGCTAGCTACAACGA TTTTGGAA
19024





583
CAAAAGUG A UCGGAAAU
8486
ATTTCCGA GGCTAGCTACAACGA CACTTTTG
19025





590
GAUCGGAA A UGACACUG
8487
CAGTGTCA GGCTAGCTACAACGA TTCCGATC
19026





593
CGGAAAUG A CACUGGAG
8488
CTCCAGTG GGCTAGCTACAACGA CATTTCCG
19027





595
GAAAUGAC A CUGGAGCC
6172
GGCTCCAG GGCTAGCTACAACGA GTCATTTC
19028





601
ACACUGGA G CCUACAAG
8489
CTTGTAGG GGCTAGCTACAACGA TCCAGTGT
19029





605
UGGAGCCU A CAAGUGCU
1546
AGCACTTG GGCTAGCTACAACGA AGGCTCCA
19030





609
GCCUACAA G UGCUUCUA
8490
TAGAAGCA GGCTAGCTACAACGA TTGTAGGC
19031





611
CUACAAGU G CUUCUACC
8491
GGTAGAAG GGCTAGCTACAACGA ACTTGTAG
19032





617
GUGCUUCU A CCGGGAAA
1549
TTTCCCGG GGCTAGCTACAACGA AGAAGCAC
19033





625
ACCGGGAA A CUGACUUG
8492
CAAGTCAG GGCTAGCTACAACGA TTCCCGGT
19034





629
GGAAACUG A CUUGGCCU
8493
AGGCCAAG GGCTAGCTACAACGA CAGTTTCC
19035





634
CUGACUUG G CCUCGGUC
8494
GACCGAGG GGCTAGCTACAACGA CAAGTCAG
19036





640
UGGCCUCG G UCAUUUAU
8495
ATAAATGA GGCTAGCTACAACGA CGAGGCCA
19037





643
CCUCGGUC A UUUAUGUC
6184
GACATAAA GGCTAGCTACAACGA GACCGAGG
19038





647
GGUCAUUU A UGUCUAUG
1555
CATAGACA GGCTAGCTACAACGA AAATGACC
19039





649
UCAUUUAU G UCUAUGUU
8496
AACATAGA GGCTAGCTACAACGA ATAAATGA
19040





653
UUAUGUCU A UGUUCAAG
1557
CTTGAACA GGCTAGCTACAACCA AGACATAA
19041





655
AUGUCUAU G UUCAAGAU
8497
ATCTTGAA GGCTAGCTACAACGA ATAGACAT
19042





662
UGUUCAAG A UUACAGAU
8498
ATCTGTAA GGCTAGCTACAACGA CTTGAACA
19043





665
UCAAGAUU A CAGAUCUC
1561
GAGATCTG GGCTAGCTACAACGA AATCTTGA
19044





669
GAUUACAG A UCUCCAUU
8499
AATGGAGA GGCTAGCTACAACGA CTGTAATC
19045





675
AGAUCUCC A UUUAUUGC
6190
GCAATAAA GGCTAGCTACAACGA GGAGATCT
19046





679
CUCCAUUU A UUGCUUCU
1566
AGAAGCAA GGCTAGCTACAACGA AAATGGAG
19047





682
CAUUUAUU G CUUCUGUU
8500
AACAGAAG GGCTAGCTACAACGA AATAAATG
19048





688
UUGCUUCU G UUAGUGAC
8501
GTCACTAA GGCTAGCTACAACGA AGAAGCAA
19049





692
UUCUGUUA G UGACCAAC
8502
GTTGGTCA GGCTAGCTACAACGA TAACAGAA
19050





695
UGUUAGUG A CCAACAUG
8503
CATGTTGG GGCTAGCTACAACGA CACTAACA
19051





699
AGUGACCA A CAUGGAGU
8504
ACTCCATG GGCTAGCTACAACGA TGGTCACT
19052





701
UGACCAAC A UGGAGUGG
6195
CGACTCCA GGCTAGCTACAACGA GTTGGTCA
19053





706
AACAUGGA G UCGUGUAC
8505
GTACACGA GGCTAGCTACAACGA TCCATGTT
19054





709
AUGGAGUC G UGUACAUU
8506
AATGTACA GGCTAGCTACAACGA GACTCCAT
19055





711
GGAGUCGU G UACAUUAC
8507
GTAATGTA GGCTAGCTACAACGA ACGACTCC
19056





713
AGUCGUGU A CAUUACUG
1573
CAGTAATG GGCTAGCTACAACGA ACACGACT
19057





715
UCGUGUAC A UUACUGAG
6196
CTCAGTAA GGCTAGCTACAACGA GTACACGA
19058





718
UGUACAUU A CUGAGAAC
1575
GTTCTCAG GGCTAGCTACAACGA AATGTACA
19059





725
UACUGAGA A CAAAAACA
8508
TGTTTTTG GGCTAGCTACAACGA TCTCAGTA
19060





731
GAACAAAA A CAAAACUG
8509
CAGTTTTG GGCTAGCTACAACGA TTTTGTTC
19061





736
AAAACAAA A CUGUGGUG
8510
CACCACAG GGCTAGCTACAACGA TTTGTTTT
19062





739
ACAAAACU G UGGUGAUU
8511
AATCACCA GGCTAGCTACAACGA AGTTTTGT
19063





742
AAACUGUG G UGAUUCCA
8512
TGGAATCA GGCTAGCTACAACGA CACAGTTT
19064





745
CUGUGGUG A UUCCAUGU
8513
ACATGGAA GGCTAGCTACAACGA CACCACAG
19065





750
GUGAUUCC A UGUCUCGG
6202
CCGAGACA GGCTAGCTACAACGA GGAATCAC
19066





752
GAUUCCAU G UCUCGGGU
8514
ACCCGAGA GGCTAGCTACAACGA ATGGAATC
19067





759
UGUCUCGG G UCCAUUUC
8515
GAAATGGA GGCTAGCTACAACGA CCGAGACA
19068





763
UCGGGUCC A UUUCAAAU
6205
ATTTGAAA GGCTAGCTACAACGA GGACCCGA
19069





770
CAUUUCAA A UCUCAACG
8516
CGTTGAGA GGCTAGCTACAACGA TTGAAATG
19070





776
AAAUCUCA A CGUGUCAC
8517
GTGACACG GGCTAGCTACAACGA TGAGATTT
19071





778
AUCUCAAC G UGUCACUU
8518
AAGTGACA GGCTAGCTACAACGA GTTGAGAT
19072





780
CUCAACGU G UCACUUUG
8519
CAAAGTGA GGCTAGCTACAACGA ACGTTGAG
19073





783
AACGUGUC A CUUUGUGC
6209
GCACAAAG GGCTAGCTACAACGA GACACGTT
19074





788
GUCACUUU G UGCAAGAU
8520
ATCTTGCA GGCTAGCTACAACGA AAAGTGAC
19075





790
CACUUUGU G CAAGAUAC
8521
GTATCTTG GGCTAGCTACAACGA ACAAAGTG
19076





795
UGUGCAAG A UACCCAGA
8522
TCTGGGTA GGCTAGCTACAACGA CTTGCACA
19077





797
UGCAAGAU A CCCAGAAA
1589
TTTCTGGG GGCTAGCTACAACGA ATCTTGCA
19078





810
GAAAAGAG A UUUGUUCC
8523
GGAACAAA GGCTAGCTACAACGA CTCTTTTC
19079





814
AGAGAUUU G UUCCUGAU
8524
ATCAGGAA GGCTAGCTACAACGA AAATCTCT
19080





821
UGUUCCUG A UGGUAACA
8525
TGTTACCA GGCTAGCTACAACGA CAGGAACA
19081





824
UCCUGAUG G UAACAGAA
8526
TTCTGTTA GGCTAGCTACAACGA CATCAGGA
19082





827
UGAUGGUA A CAGAAUUU
8527
AAATTCTG GGCTAGCTACAACGA TACCATCA
19083





832
GUAACAGA A UUUCCUGG
8528
CCAGGAAA GGCTAGCTACAACGA TCTGTTAC
19084





842
UUCCUGGG A CAGCAAGA
8529
TCTTGCTG GGCTAGCTACAACGA CCCAGGAA
19085





845
CUGGGACA G CAAGAAGG
8530
CCTTCTTG GGCTAGCTACAACGA TGTCCCAG
19086





854
CAAGAAGG G CUUUACUA
8531
TAGTAAAG GGCTAGCTACAACGA CCTTCTTG
19087





859
AGGGCUUU A CUAUUCCC
1600
GGGAATAG GGCTAGCTACAACGA AAAGCCCT
19088





862
GCUUUACU A UUCCCAGC
1601
GCTGGGAA GGCTAGCTACAACGA AGTAAAGC
19089





869
UAUUCCCA G CUACAUGA
8532
TCATGTAG GGCTAGCTACAACGA TGGGAATA
19090





872
UCCCAGCU A CAUGAUCA
1604
TGATCATG GGCTAGCTACAACGA AGCTGGGA
19091





874
CCAGCUAC A UGAUCAGC
6228
GCTGATCA GGCTAGCTACAACGA GTAGCTGG
19092





877
GCUACAUG A UCAGCUAU
8533
ATAGCTGA GGCTAGCTACAACGA CATGTAGC
19093





881
CAUGAUCA G CUAUGCUG
8534
CAGCATAG GGCTAGCTACAACGA TGATCATG
19094





884
GAUCAGCU A UGCUGGCA
1606
TGCCAGCA GGCTAGCTACAACGA AGCTGATC
19095





886
UCAGCUAU G CUGGCAUG
8535
CATGCCAG GGCTAGCTACAACGA ATAGCTGA
19096





890
CUAUGCUG G CAUGGUCU
8536
AGACCATG GGCTAGCTACAACGA CAGCATAG
19097





892
AUGCUGGC A UGGUCUUC
6232
GAAGACCA GGCTAGCTACAACGA GCCAGCAT
19098





895
CUGGCAUG G UCUUCUGU
8537
ACAGAAGA GGCTAGCTACAACGA CATGCCAG
19099





902
GGUCUUCU G UGAAGCAA
8538
TTGCTTCA GGCTAGCTACAACGA AGAAGACC
19100





907
UCUGUGAA G CAAAAAUU
8539
AATTTTTG GGCTAGCTACAACGA TTCACAGA
19101





913
AAGCAAAA A UUAAUGAU
8540
ATCATTAA GGCTAGCTACAACGA TTTTGCTT
19102





917
AAAAAUUA A UGAUGAAA
8541
TTTCATCA GGCTAGCTACAACGA TAATTTTT
19103





920
AAUUAAUG A UGAAAGUU
8542
AACTTTCA GGCTAGCTACAACGA CATTAATT
19104





926
UGAUGAAA G UUACCAGU
8543
ACTGGTAA GGCTAGCTACAACGA TTTCATCA
19105





929
UGAAAGUU A CCAGUCUA
1613
TAGACTGG GGCTAGCTACAACGA AACTTTCA
19160





933
AGUUACCA G UCUAUUAU
8544
ATAATAGA GGCTAGCTACAACGA TGGTAACT
19107





937
ACCAGUCU A UUAUGUAC
1615
GTACATAA GGCTAGCTACAACGA AGACTGGT
19108





940
AGUCUAUU A UGUACAUA
1617
TATGTACA GGCTAGCTACAACGA AATAGACT
19109





942
UCUAUUAU G UACAUAGU
8545
ACTATGTA GGCTAGCTACAACGA ATAATAGA
19110





944
UAUUAUGU A CAUAGUUG
1618
CAACTATG GGCTAGCTACAACGA ACATAATA
19111





946
UUAUGUAC A UAGUUGUC
6239
GACAACTA GGCTAGCTACAACGA GTACATAA
19112





949
UGUACAUA G UUGUCGUU
8546
AACGACAA GGCTAGCTACAACGA TATGTACA
19113





952
ACAUAGUU G UCGUUGUA
8547
TACAACGA GGCTAGCTACAACGA AACTATGT
19114





955
UAGUUGUC G UUGUAGGG
8548
CCCTACAA GGCTAGCTACAACGA GACAACTA
19115





958
UUGUCGUU G UAGGGUAU
8549
ATACCCTA GGCTAGCTACAACGA AACGACAA
19116





963
GUUGUAGG G UAUAGGAU
8550
ATCCTATA GGCTAGCTACAACGA CCTACAAC
19117





965
UGUAGGGU A UAGGAUUU
1624
AAATCCTA GGCTAGCTACAACGA ACCCTACA
19118





970
GGUAUAGG A UUUAUGAU
8551
ATCATAAA GGCTAGCTACAACGA CCTATACC
19119





974
UAGGAUUU A UGAUGUGG
1628
CCACATCA GGCTAGCTACAACGA AAATCCTA
19120





977
GAUUUAUG A UGUGGUUC
8552
GAACCACA GGCTAGCTACAACGA CATAAATC
19121





979
UUUAUGAU G UGGUUCUG
8553
CAGAACCA GGCTAGCTACAACGA ATCATAAA
19122





982
AUGAUGUG G UUCUGAGU
8554
ACTCAGAA GGCTAGCTACAACGA CACATCAT
19123





989
GGUUCUGA G UCCGUCUC
8555
GAGACGGA GGCTAGCTACAACGA TCAGAACC
19124





993
CUGAGUCC G UCUCAUGG
8556
CCATGAGA GGCTAGCTACAACGA GGACTCAG
19125





998
UCCGUCUC A UGGAAUUG
6243
CAATTCCA GGCTAGCTACAACGA GAGACGGA
19126





1003
CUCAUGGA A UUGAACUA
8557
TAGTTCAA GGCTAGCTACAACGA TCCATGAG
19127





1008
GGAAUUGA A CUAUCUGU
8558
ACAGATAG GGCTAGCTACAACGA TCAATTCC
19128





1011
AUUGAACU A UCUGUUGG
1635
CCAACAGA GGCTAGCTACAACGA AGTTCAAT
19129





1015
AACUAUCU G UUGGAGAA
8559
TTCTCCAA GGCTAGCTACAACGA AGATAGTT
19130





1026
GGAGAAAA G CUUGUCUU
8560
AAGACAAG GGCTAGCTACAACGA TTTTCTCC
19131





1030
AAAAGCUU G UCUUAAAU
8561
ATTTAAGA GGCTAGCTACAACGA AAGCTTTT
19132





1037
UGUCUUAA A UUGUACAG
8562
CTGTACAA GGCTAGCTACAACGA TTAAGACA
19133





1040
CUUAAAUU G UACAGCAA
8563
TTGCTGTA GGCTAGCTACAACGA AATTTAAG
19134





1042
UAAAUUGU A CAGCAAGA
1643
TCTTGCTG GGCTAGCTACAACGA ACAATTTA
19135





1045
AUUGUACA G CAAGAACU
8564
AGTTCTTG GGCTAGCTACAACGA TGTACAAT
19136





1051
CAGCAAGA A CUGAACUA
8565
TAGTTCAG GGCTAGCTACAACGA TCTTGCTG
19137





1056
AGAACUGA A CUAAAUGU
8566
ACATTTAG GGCTAGCTACAACGA TCAGTTCT
19138





1061
UGAACUAA A UGUGGGGA
8567
TCCCCACA GGCTAGCTACAACGA TTAGTTCA
19139





1063
AACUAAAU G UGGGGAUU
8568
AATCCCCA GGCTAGCTACAACGA ATTTAGTT
19140





1069
AUGUGGGG A UUGACUUC
8569
GAAGTCAA GGCTAGCTACAACGA CCCCACAT
19141





1073
CGGGAUUG A CUUCAACU
8570
AGTTGAAG GGCTAGCTACAACGA CAATCCCC
19142





1079
UGACUUCA A CUGGGAAU
8571
ATTCCCAG GGCTAGCTACAACGA TGAAGTCA
19143





1086
AACUGGGA A UACCCUUC
8572
GAAGGGTA GGCTAGCTACAACGA TCCCAGTT
19144





1088
CUGGGAAU A CCCUUCUU
1648
AAGAAGGG GGCTAGCTACAACGA ATTCCCAG
19145





1101
UCUUCGAA G CAUCAGCA
8573
TGCTGATG GGCTAGCTACAACGA TTCGAAGA
19146





1103
UUCGAAGC A UCAGCAUA
6259
TATGCTGA GGCTAGCTACAACGA GCTTCGAA
19147





1107
AAGCAUCA G CAUAAGAA
8574
TTCTTATG GGCTAGCTACAACGA TGATGCTT
19148





1109
GCAUCAGC A UAAGAAAC
6261
GTTTCTTA GGCTAGCTACAACGA GCTGATGC
19149





1116
CAUAAGAA A CUUGUAAA
8575
TTTACAAG GGCTAGCTACAACGA TTCTTATG
19150





1120
AGAAACUU G UAAACCGA
8576
TCGGTTTA GGCTAGCTACAACGA AAGTTTCT
19151





1124
ACUUGUAA A CCGAGACC
8577
GGTCTCGG GGCTAGCTACAACGA TTACAAGT
19152





1130
AAACCGAG A CCUAAAAA
8578
TTTTTAGG GGCTAGCTACAACGA CTCGGTTT
19153





1138
ACCUAAAA A CCCAGUCU
8579
AGACTGGG GGCTAGCTACAACGA TTTTAGGT
19154





1143
AAAACCCA G UCUGGGAG
8580
CTCCCAGA GGCTAGCTACAACGA TGGGTTTT
19155





1151
GUCUGGGA G UGAGAUGA
8581
TCATCTCA GGCTAGCTACAACGA TCCCAGAC
19156





1156
GGAGUGAG A UGAAGAAA
8582
TTTCTTCA GGCTAGCTACAACGA CTCACTCC
19157





1164
AUGAAGAA A UUUUUGAG
8583
CTCAAAAA GGCTAGCTACAACGA TTCTTCAT
19158





1172
AUUUUUGA G CACCUUAA
8584
TTAAGGTG GGCTAGCTACAACGA TCAAAAAT
19159





1174
UUUUGAGC A CCUUAACU
6270
AGTTAAGG GGCTAGCTACAACGA GCTCAAAA
19160





1180
GCACCUUA A CUAUAGAU
8585
ATCTATAG GGCTAGCTACAACGA TAAGGTGC
19161





1183
CCUUAACU A UAGAUGGU
1665
ACCATCTA GGCTAGCTACAACGA AGTTAAGG
19162





1187
AACUAUAG A UGGUGUAA
8586
TTACACCA GGCTAGCTACAACGA CTATAGTT
19163





1190
UAUAGAUG G UGUAACCC
8587
GGGTTACA GGCTAGCTACAACGA CATCTATA
19164





1192
UAGAUGGU G UAACCCGG
8588
CCGGGTTA GGCTAGCTACAACGA ACCATCTA
19165





1195
AUGGUGUA A CCCGGAGU
8589
ACTCCGGG GGCTAGCTACAACGA TACACCAT
19166





1202
AACCCGGA G UGACCAAG
8590
CTTGGTCA GGCTAGCTACAACGA TCCGGGTT
19167





1205
CCGGAGUG A CCAAGGAU
8591
ATCCTTGG GGCTAGCTACAACGA CACTCCGG
19168





1212
GACCAAGG A UUGUACAC
8592
GTGTACAA GGCTAGCTACAACGA CCTTGGTC
19169





1215
CAAGGAUU G UACACCUG
8593
CAGGTGTA GGCTAGCTACAACGA AATCCTTG
19170





1217
AGGAUUGU A CACCUGUG
1669
CACAGGTG GGCTAGCTACAACGA ACAATCCT
19171





1219
GAUUGUAC A CCUGUGCA
6278
TGCACAGG GGCTAGCTACAACGA GTACAATC
19172





1223
GUACACCU G UGCAGCAU
8594
ATGCTGCA GGCTAGCTACAACGA AGGTGTAC
19173





1225
ACACCUGU G CAGCAUCC
8595
GGATGCTG GGCTAGCTACAACGA ACAGGTGT
19174





1228
CCUGUGCA G CAUCCAGU
8596
ACTGGATG GGCTAGCTACAACGA TGCACAGG
19175





1230
UGUGCAGC A UCCAGUGG
6282
CCACTGGA GGCTAGCTACAACGA GCTGCACA
19176





1235
AGCAUCCA G UGGGCUGA
8597
TCAGCCCA GGCTAGCTACAACGA TGGATGCT
19177





1239
UCCAGUGG G CUGAUGAC
8598
GTCATCAG GGCTAGCTACAACGA CCACTGGA
19178





1243
GUGGGCUG A UGACCAAG
8599
CTTGGTCA GGCTAGCTACAACGA CAGCCCAC
19179





1246
GGCUGAUG A CCAAGAAG
8600
CTTCTTGG GGCTAGCTACAACGA CATCAGCC
19180





1256
CAAGAAGA A CAGCACAU
8601
ATGTGCTG GGCTAGCTACAACGA TCTTCTTG
19181





1259
GAAGAACA G CACAUUUG
8602
CAAATGTG GGCTAGCTACAACGA TGTTCTTC
19182





1261
AGAACAGC A CAUUUGUC
6289
GACAAATG GGCTAGCTACAACGA GCTGTTCT
19183





1263
AACAGCAC A UUUGUCAG
6290
CTGACAAA GGCTAGCTACAACGA GTGCTGTT
19184





1267
GCACAUUU G UCAGGGUC
8603
GACCCTGA GGCTAGCTACAACGA AAATGTGC
19185





1273
UUGUCAGG G UCCAUGAA
8604
TTCATGGA GGCTAGCTACAACGA CCTGACAA
19186





1277
CAGGGUCC A UGAAAAAC
6293
GTTTTTCA GGCTAGCTACAACGA GGACCCTG
19187





1284
CAUGAAAA A CCUUUUGU
8605
ACAAAAGG GGCTAGCTACAACGA TTTTCATG
19188





1291
AACCUUUU G UUGCUUUU
8606
AAAAGCAA GGCTAGCTACAACGA AAAAGGTT
19189





1294
CUUUUGUU G CUUUUGGA
8607
TCCAAAAG GGCTAGCTACAACGA AACAAAAG
19190





1304
UUUUGGAA G UGGCAUGG
8608
CCATGCCA GGCTAGCTACAACGA TTCCAAAA
19191





1307
UGGAAGUG G CAUGGAAU
8609
ATTCCATG GGCTAGCTACAACGA CACTTCCA
19192





1309
GAAGUGGC A UGGAAUCU
6297
AGATTCCA GGCTAGCTACAACGA GCCACTTC
19193





1314
GGCAUGGA A UCUCUGGU
8610
ACCAGAGA GGCTAGCTACAACGA TCCATGCC
19194





1321
AAUCUCUG G UGGAAGCC
8611
GGCTTCCA GCCTAGCTACAACGA CAGAGATT
19195





1327
UGGUGGAA G CCACGGUG
8612
CACCGTGG GGCTAGCTACAACGA TTCCACCA
19196





1330
UGGAAGCC A CGGUGGGG
6301
CCCCACCG GGCTAGCTACAACGA GGCTTCCA
19197





1333
AAGCCACG G UGGGGGAG
8613
CTCCCCCA GGCTAGCTACAACGA CGTGGCTT
19198





1341
GUGGGGGA G CGUGUCAG
8614
CTGACACG GGCTAGCTACAACGA TCCCCCAC
19199





1343
GGGGGAGC G UGUCAGAA
8615
TTCTGACA GGCTAGCTACAACGA GCTCCCCC
19200





1345
GGGAGCGU G UCAGAAUC
8616
GATTCTGA GGCTAGCTACAACGA ACGCTCCC
19201





1351
GUGUCAGA A UCCCUGCG
8617
CGCAGGGA GGCTAGCTACAACGA TCTGACAC
19202





1357
GAAUCCCU G CGAAGUAC
8618
GTACTTCG GGCTAGCTACAACGA AGGGATTC
19203





1362
CCUGCGAA G UACCUUGG
8619
CCAAGGTA GCCTAGCTACAACGA TTCGCAGG
19204





1364
UGCGAAGU A CCUUGGUU
1686
AACCAAGG GCCTAGCTACAACGA ACTTCGCA
19205





1370
GUACCUUG G UUACCCAC
8620
GTGGGTAA GGCTAGCTACAACGA CAAGGTAC
19206





1373
CCUUGGUU A CCCACCCC
1689
GGGGTGGG GGCTAGCTACAACGA AACCAAGG
19207





1377
GGUUACCC A CCCCCAGA
6310
TCTGGGGG GGCTAGCTACAACGA GGGTAACC
19208





1387
CCCCAGAA A UAAAAUGG
8621
CCATTTTA GGCTAGCTACAACGA TTCTGGGG
19209





1392
GAAAUAAA A UGGUAUAA
8622
TTATACCA GGCTAGCTACAACGA TTTATTTC
19210





1395
AUAAAAUG G UAUAAAAA
8623
TTTTTATA GGCTAGCTACAACGA CATTTTAT
19211





1397
AAAAUGGU A UAAAAAUG
1691
CATTTTTA GGCTAGCTACAACGA ACCATTTT
19212





1403
GUAUAAAA A UGGAAUAC
8624
GTATTCCA GGCTAGCTACAACGA TTTTATAC
19213





1408
AAAAUGGA A UACCCCUU
8625
AAGGGGTA GGCTAGCTACAACGA TCCATTTT
19214





1410
AAUGGAAU A CCCCUUGA
1693
TCAAGGGG GGCTAGCTACAACGA ATTCCATT
19215





1419
CCCCUUGA G UCCAAUCA
8626
TGATTGGA GGCTAGCTACAACGA TCAAGGGG
19216





1424
UGAGUCCA A UCACACAA
8627
TTGTGTGA GGCTAGCTACAACGA TGGACTCA
19217





1427
GUCCAAUC A CACAAUUA
6322
TAATTGTG GGCTAGCTACAACGA GATTGGAC
19218





1429
CCAAUCAC A CAAUUAAA
6323
TTTAATTG GGCTAGCTACAACGA GTCATTGG
19219





1432
AUCACACA A UUAAAGCG
8628
CGCTTTAA GGCTAGCTACAACGA TGTGTGAT
19220





1438
CAAUUAAA G CGGGGCAU
8629
ATGCCCCG GGCTAGCTACAACGA TTTAATTG
19221





1443
AAAGCGGG G CAUGUACU
8630
AGTACATG GGCTAGCTACAACGA CCCGCTTT
19222





1445
AGCGGGGC A UGUACUGA
6325
TCAGTACA GGCTAGCTACAACGA GCCCCGCT
19223





1447
CGGGGCAU G UACUGACG
8631
CGTCAGTA GGCTAGCTACAACGA ATGCCCCG
19224





1449
GGGCAUGU A CUGACGAU
1699
ATCGTCAG GGCTAGCTACAACGA ACATGCCC
19225





1453
AUGUACUG A CGAUUAUG
8632
CATAATCG GCCTAGCTACAACGA CAGTACAT
19226





1456
UACUGACG A UUAUGGAA
8633
TTCCATAA GGCTAGCTACAACGA CGTCAGTA
19227





1459
UGACGAUU A UGGAAGUG
1701
CACTTCCA GGCTAGCTACAACGA AATCGTCA
19228





1465
UUAUGGAA G UGAGUGAA
8634
TTCACTCA GGCTAGCTACAACGA TTCCATAA
19229





1469
GGAAGUGA G UGAAAGAG
8635
CTCTTTCA GGCTAGCTACAACGA TCACTTCC
19230





1478
UGAAAGAG A CACAGGAA
8636
TTCCTGTG GCCTAGCTACAACGA CTCTTTCA
19231





1480
AAAGAGAC A CAGGAAAU
6327
ATTTCCTG GGCTAGCTACAACGA GTCTCTTT
19232





1487
CACAGGAA A UUACACUG
8637
CAGTGTAA GGCTAGCTACAACGA TTCCTGTG
19233





1490
AGGAAAUU A CACUGUCA
1703
TGACAGTG GGCTAGCTACAACGA AATTTCCT
19234





1492
GAAAUUAC A CUGUCAUC
6329
GATGACAG GGCTAGCTACAACGA GTAATTTC
19235





1495
AUUACACU G UCAUCCUU
8638
AAGGATGA GGCTAGCTACAACGA AGTGTAAT
19236





1498
ACACUGUC A UCCUUACC
6331
GGTAAGGA GGCTAGCTACAACGA GACAGTGT
19237





1504
UCAUCCUU A CCAAUCCC
1707
GGGATTGG GGCTAGCTACAACGA AAGGATGA
19238





1508
CCUUACCA A UCCCAUUU
8639
AAATGGGA GGCTAGCTACAACGA TGGTAAGG
19239





1513
CCAAUCCC A UUUCAAAG
6338
CTTTGAAA GGCTAGCTACAACGA GGGATTGG
19240





1527
AAGGAGAA G CAGAGCCA
8640
TGGCTCTG GGCTAGCTACAACGA TTCTCCTT
19241





1532
GAAGCAGA G CCAUGUGG
8641
CCACATGG GGCTAGCTACAACGA TCTGCTTC
19242





1535
GCAGAGCC A UGUGGUCU
6342
AGACCACA GGCTAGCTACAACGA GGCTCTGC
19243





1537
AGAGCCAU G UGGUCUCU
8642
AGAGACCA GGCTAGCTACAACGA ATGGCTCT
19244





1540
GCCAUGUG G UCUCUCUG
8643
CAGAGAGA GGCTAGCTACAACGA CACATGGC
19245





1549
UCUCUCUG G UUGUGUAU
8644
ATACACAA GGCTAGCTACAACGA CAGAGAGA
19246





1552
CUCUGGUU G UGUAUGUC
8645
GACATACA GGCTAGCTACAACGA AACCAGAG
19247





1554
CUGGUUGU G UAUGUCCC
8646
GGGACATA GGCTAGCTACAACGA ACAACCAG
19248





1556
GGUUGUGU A UGUCCCAC
1716
GTGGGACA GGCTAGCTACAACGA ACACAACC
19249





1558
UUGUGUAU G UCCCACCC
8647
GGGTGGGA GGCTAGCTACAACGA ATACACAA
19250





1563
UAUGUCCC A CCCCAGAU
6348
ATCTGGGG GGCTAGCTACAACGA GGGACATA
19251





1570
CACCCCAG A UUGGUGAG
8648
CTCACCAA GGCTAGCTACAACGA CTGGGGTG
19252





1574
CCAGAUUG G UGAGAAAU
8649
ATTTCTCA GGCTAGCTACAACGA CAATCTGG
19253





1581
GGUGAGAA A UCUCUAAU
8650
ATTAGAGA GGCTAGCTACAACGA TTCTCACC
19254





1588
AAUCUCUA A UCUCUCCU
8651
AGGAGAGA GGCTAGCTACAACGA TAGAGATT
19255





1597
UCUCUCCU G UGGAUUCC
8652
GGAATCCA GGCTAGCTACAACGA AGGAGAGA
19256





1601
UCCUGUGG A UUCCUACC
8653
GGTAGGAA GGCTAGCTACAACGA CCACAGGA
19257





1607
GGAUUCCU A CCAGUACG
1727
CGTACTGG GGCTAGCTACAACGA AGGAATCC
19258





1611
UCCUACCA G UACGGCAC
8654
GTGCCGTA GGCTAGCTACAACGA TGGTAGGA
19259





1613
CUACCAGU A CGGCACCA
1728
TGGTGCCG GGCTAGCTACAACGA ACTGGTAG
19260





1616
CCAGUACG G CACCACUC
8655
GAGTGGTG GGCTAGCTACAACGA CGTACTGG
19261





1618
AGUACGGC A CCACUCAA
6363
TTGAGTGG GGCTAGCTACAACGA GCCGTACT
19262





1621
ACGGCACC A CUCAAACG
6365
CGTTTGAG GGCTAGCTACAACGA GGTGCCGT
19263





1627
CCACUCAA A CGCUGACA
8656
TGTCAGCG GGCTAGCTACAACGA TTGAGTGG
19264





1629
ACUCAAAC G CUGACAUG
8657
CATGTCAG GGCTAGCTACAACGA GTTTGAGT
19265





1633
AAACGCUG A CAUGUACG
8658
CGTACATG GGCTAGCTACAACGA CAGCGTTT
19266





1635
ACGCUGAC A UGUACGGU
6369
ACCGTACA GGCTAGCTACAACGA GTCAGCGT
19267





1637
GCUGACAU G UACGGUCU
8659
AGACCGTA GGCTAGCTACAACGA ATGTCAGC
19268





1639
UGACAUGU A CGGUCUAU
1730
ATAGACCG GGCTAGCTACAACGA ACATGTCA
19269





1642
CAUGUACG G UCUAUGCC
8660
GGCATAGA GGCTAGCTACAACGA CGTACATG
19270





1646
UACGGUCU A UGCCAUUC
1732
GAATGGCA GGCTAGCTACAACGA AGACCGTA
19271





1648
CGGUCUAU G CCAUUCCU
8661
AGGAATGG GGCTAGCTACAACGA ATAGACCG
19272





1651
UCUAUGCC A UUCCUCCC
6372
GGGAGGAA GGCTAGCTACAACGA GGCATAGA
19273





1662
CCUCCCCC G CAUCACAU
8662
ATGTGATG GGCTAGCTACAACGA GGGGGAGG
19274





1664
UCCCCCGC A UCACAUCC
6379
GGATGTGA GGCTAGCTACAACGA GCGGGGGA
19275





1667
CCCGCAUC A CAUCCACU
6380
AGTGGATG GGCTAGCTACAACGA GATGCGGG
19276





1669
CGCAUCAC A UCCACUGG
6381
CCAGTGGA GGCTAGCTACAACGA GTGATGCG
19277





1673
UCACAUCC A CUGGUAUU
6383
AATACCAG GGCTAGCTACAACGA GGATGTGA
19278





1677
AUCCACUG G UAUUGGCA
8663
TGCCAATA GGCTAGCTACAACGA CAGTGGAT
19279





1679
CCACUGGU A UUGGCAGU
1738
ACTGCCAA GGCTAGCTACAACGA ACCAGTGG
19280





1683
UGGUAUUG G CAGUUGGA
8664
TCCAACTG GGCTAGCTACAACGA CAATACCA
19281





1686
UAUUGGCA G UUGGAGGA
8665
TCCTCCAA GGCTAGCTACAACGA TGCCAATA
19282





1698
GAGGAAGA G UGCGCCAA
8666
TTGGCGCA GGCTAGCTACAACGA TCTTCCTC
19283





1700
GGAAGAGU G CGCCAACG
8667
CGTTGGCG GGCTAGCTACAACGA ACTCTTCC
19284





1702
AAGAGUGC G CCAACGAG
8668
CTCGTTGC GGCTAGCTACAACGA GCACTCTT
19285





1706
GUGCGCCA A CGAGCCCA
8669
TGGGCTCG GGCTAGCTACAACGA TGGCGCAC
19286





1710
GCCAACGA G CCCAGCCA
8670
TGGCTGGG GGCTAGCTACAACGA TCGTTGGC
19287





1715
CGAGCCCA G CCAAGCUG
8671
CAGCTTGG GGCTAGCTACAACGA TGGGCTCG
19288





1720
CCAGCCAA G CUGUCUCA
8672
TGAGACAG GGCTAGCTACAACGA TTGGCTGG
19289





1723
GCCAAGCU G UCUCAGUG
8673
CACTGAGA GGCTAGCTACAACGA AGCTTGGC
19290





1729
CUGUCUCA G UGACAAAC
8674
GTTTGTCA GGCTAGCTACAACGA TGAGACAG
19291





1732
UCUCAGUG A CAAACCCA
8675
TGGGTTTG GGCTAGCTACAACGA CACTGAGA
19292





1736
AGUGACAA A CCCAUACC
8676
GGTATGGG GGCTAGCTACAACGA TTGTCACT
19293





1740
ACAAACCC A UACCCUUG
6399
CAAGGGTA GGCTAGCTACAACGA GGGTTTGT
19294





1742
AAACCCAU A CCCUUGUG
1743
CACAAGGG GGCTAGCTACAACGA ATGGGTTT
19295





1748
AUACCCUU G UGAAGAAU
8677
ATTCTTCA GGCTAGCTACAACGA AAGGGTAT
19296





1755
UGUGAAGA A UGGAGAAG
8678
CTTCTCCA GGCTAGCTACAACGA TCTTCACA
19297





1763
AUGGAGAA G UGUGGAGG
8679
CCTCCACA GGCTAGCTACAACGA TTCTCCAT
19298





1765
GGAGAAGU G UGGAGGAC
8680
GTCCTCCA GGCTAGCTACAACGA ACTTCTCC
19299





1772
UGUGGAGG A CUUCCAGG
8681
CCTGGAAG GGCTAGCTACAACGA CCTCCACA
19300





1787
GGGAGGAA A UAAAAUUG
8682
CAATTTTA GGCTAGCTACAACGA TTCCTCCC
19301





1792
GAAAUAAA A UUGAAGUU
8683
AACTTCAA GGCTAGCTACAACGA TTTATTTC
19302





1798
AAAUUGAA G UUAAUAAA
8684
TTTATTAA GGCTAGCTACAACGA TTCAATTT
19303





1802
UGAAGUUA A UAAAAAUC
8685
GATTTTTA GGCTAGCTACAACGA TAACTTCA
19304





1808
UAAUAAAA A UCAAUUUG
8686
CAAATTGA GGCTAGCTACAACGA TTTTATTA
19305





1812
AAAAAUCA A UUUGCUCU
8687
AGAGCAAA GGCTAGCTACAACGA TGATTTTT
19306





1816
AUCAAUUU G CUCUAAUU
8688
AATTAGAG GGCTAGCTACAACGA AAATTGAT
19307





1822
UUGCUCUA A UUGAAGGA
8689
TCCTTCAA GGCTAGCTACAACGA TAGAGCAA
19308





1835
AGGAAAAA A CAAAACUG
8690
CAGTTTTG GGCTAGCTACAACGA TTTTTCCT
19309





1840
AAAACAAA A CUGUAAGU
8691
ACTTACAG GCCTAGCTACAACGA TTTGTTTT
19310





1843
ACAAAACU G UAAGUACC
8692
GGTACTTA GGCTAGCTACAACGA AGTTTTGT
19311





1847
AACUGUAA G UACCCUUG
8693
CAAGGGTA GGCTAGCTACAACGA TTACAGTT
19312





1849
CUGUAAGU A CCCUUGUU
1759
AACAAGGG GGCTAGCTACAACGA ACTTACAG
19313





1855
GUACCCUU G UUAUCCAA
8694
TTGGATAA GGCTAGCTACAACGA AAGGGTAC
19314





1858
CCCUUGUU A UCCAAGCG
1762
CGCTTGGA GGCTAGCTACAACGA AACAAGGG
19315





1864
UUAUCCAA G CGGCAAAU
8695
ATTTGCCG GGCTAGCTACAACGA TTGGATAA
19316





1867
UCCAAGCG G CAAAUGUG
8696
CACATTTG GGCTAGCTACAACGA CGCTTGGA
19317





1871
AGCGGCAA A UCUGUCAG
8697
CTGACACA GGCTAGCTACAACGA TTGCCGCT
19318





1873
CGGCAAAU G UGUCAGCU
8698
AGCTGACA GGCTAGCTACAACGA ATTTGCCG
19319





1875
GCAAAUGU G UCAGCUUU
8699
AAAGCTGA GGCTAGCTACAACGA ACATTTGC
19320





1879
AUGUGUCA G CUUUGUAC
8700
GTACAAAG GGCTAGCTACAACGA TGACACAT
19321





1884
UCAGCUUU G UACAAAUG
8701
CATTTGTA GGCTAGCTACAACGA AAAGCTGA
19322





1886
AGCUUUGU A CAAAUGUG
1767
CACATTTG GGCTAGCTACAACGA ACAAAGCT
19323





1890
UUGUACAA A UGUGAAGC
8702
GCTTCACA GGCTAGCTACAACGA TTGTACAA
19324





1892
GUACAAAU G UGAAGCGG
8703
CCGCTTCA GGCTAGCTACAACGA ATTTGTAC
19325





1897
AAUGUGAA G CGGUCAAC
8704
GTTGACCG GGCTAGCTACAACGA TTCACATT
19326





1900
GUGAAGCG G UCAACAAA
8705
TTTGTTGA GGCTAGCTACAACGA CGCTTCAC
19327





1904
AGCGGUCA A CAAAGUCG
8706
CGACTTTG GCCTAGCTACAACGA TGACCGCT
19328





1909
UCAACAAA G UCGGGAGA
8707
TCTCCCGA GGCTACCTACAACGA TTTGTTGA
19329





1927
GAGAGAGG G UGAUCUCC
8708
GGAGATCA GGCTAGCTACAACGA CCTCTCTC
19330





1930
AGAGGGUG A UCUCCUUC
8709
GAAGGAGA GGCTAGCTACAACGA CACCCTCT
19331





1940
CUCCUUCC A CGUGACCA
6426
TGGTCACG GGCTAGCTACAACGA GGAAGGAG
19332





1942
CCUUCCAC G UGACCAGG
8710
CCTGGTCA GGCTAGCTACAACGA GTGGAAGG
19333





1945
UCCACGUG A CCAGGGGU
8711
ACCCCTGG GGCTAGCTACAACGA CACGTGGA
19334





1952
GACCAGGG G UCCUGAAA
8712
TTTCAGGA GGCTAGCTACAACGA CCCTGGTC
19335





1960
GUCCUGAA A UUACUUUG
8713
CAAAGTAA GGCTAGCTACAACGA TTCAGGAC
19336





1963
CUGAAAUU A CUUUGCAA
1776
TTGCAAAG GGCTAGCTACAACGA AATTTCAG
19337





1968
AUUACUUU G CAACCUGA
8714
TCAGGTTG GGCTAGCTACAACGA AAAGTAAT
19338





1971
ACUUUGCA A CCUGACAU
8715
ATGTCAGG GGCTAGCTACAACGA TGCAAAGT
19339





1976
GCAACCUG A CAUGCAGC
8716
GCTGCATG GGCTAGCTACAACGA CAGGTTGC
19340





1978
AACCUGAC A UGCAGCCC
6435
GGGCTGCA GGCTAGCTACAACGA GTCAGGTT
19341





1980
CCUGACAU G CAGCCCAC
8717
GTGGGCTG GGCTAGCTACAACGA ATGTCAGG
19342





1983
GACAUGCA G CCCACUGA
8718
TCAGTGGG GGCTAGCTACAACGA TGCATGTC
19343





1987
UGCAGCCC A CUGAGCAG
6439
CTGCTCAG GGCTAGCTACAACGA GGGCTGCA
19344





1992
CCCACUGA G CAGGAGAG
8719
CTCTCCTG GGCTAGCTACAACGA TCAGTGGG
19345





2000
GCAGGAGA G CGUGUCUU
8720
AAGACACG GGCTAGCTACAACGA TCTCCTGC
19346





2002
AGGAGAGC G UGUCUUUG
8721
CAAAGACA GGCTAGCTACAACGA GCTCTCCT
19347





2004
GAGAGCGU G UCUUUGUG
8722
CACAAAGA GGCTAGCTACAACGA ACGCTCTC
19348





2010
GUGUCUUU G UGGUGCAC
8723
GTGCACCA GGCTAGCTACAACGA AAAGACAC
19349





2013
UCUUUGUG G UGCACUGC
8724
GCAGTGCA GGCTAGCTACAACGA CACAAAGA
19350





2015
UUUGUGGU G CACUGCAG
8725
CTGCAGTG GGCTAGCTACAACGA ACCACAAA
19351





2017
UGUGGUGC A CUGCAGAC
6443
GTCTGCAG GGCTAGCTACAACGA GCACCACA
19352





2020
GGUGCACU G CAGACAGA
8726
TCTGTCTG GGCTAGCTACAACGA AGTGCACC
19353





2024
CACUGCAG A CAGAUCUA
8727
TAGATCTG GGCTAGCTACAACGA CTGCAGTG
19354





2028
GCAGACAG A UCUACGUU
8728
AACGTAGA GGCTAGCTACAACGA CTGTCTGC
19355





2032
ACAGAUCU A CGUUUGAG
1783
CTCAAACG GGCTAGCTACAACGA AGATCTGT
19356





2034
AGAUCUAC G UUUGAGAA
8729
TTCTCAAA GGCTAGCTACAACGA GTAGATCT
19357





2042
GUUUGAGA A CCUCACAU
8730
ATGTGAGG GGCTAGCTACAACGA TCTCAAAC
19358





2047
AGAACCUC A CAUGGUAC
6450
GTACCATG GGCTAGCTACAACGA GAGGTTCT
19359





2049
AACCUCAC A UGGUACAA
6451
TTGTACCA GGCTAGCTACAACGA GTGAGGTT
19360





2052
CUCACAUG G UACAAGCU
8731
AGCTTGTA GGCTAGCTACAACGA CATGTGAG
19361





2054
CACAUGGU A CAAGCUUG
1787
CAAGCTTG GGCTAGCTACAACGA ACCATGTG
19362





2058
UGGUACAA G CUUGGCCC
8732
GGGCCAAG GGCTAGCTACAACGA TTGTACCA
19363





2063
CAAGCUUG G CCCACAGC
8733
GCTGTGGG GGCTAGCTACAACGA CAAGCTTG
19364





2067
CUUGGCCC A CAGCCUCU
6456
AGAGGCTG GGCTAGCTACAACGA GGGCCAAG
19365





2070
GGCCCACA G CCUCUGCC
8734
GGCAGAGG GGCTAGCTACAACGA TGTGGGCC
19366





2076
CAGCCUCU G CCAAUCCA
8735
TGGATTGG GGCTAGCTACAACGA AGAGGCTG
19367





2080
CUCUGCCA A UCCAUGUG
8736
CACATGGA GGCTAGCTACAACGA TGGCAGAG
19368





2084
GCCAAUCC A UGUGGGAG
6464
CTCCCACA GGCTAGCTACAACGA GGATTGGC
19369





2086
CAAUCCAU G UGGGAGAG
8737
CTCTCCCA GGCTAGCTACAACGA ATGGATTG
19370





2094
GUGGGAGA G UUGCCCAC
8738
GTGGGCAA GGCTAGCTACAACGA TCTCCCAC
19371





2097
GGAGAGUU G CCCACACC
8739
GGTGTGGG GGCTAGCTACAACGA AACTCTCC
19372





2101
AGUUGCCC A CACCUGUU
6467
AACAGGTG GGCTAGCTACAACGA GGGCAACT
19373





2103
UUGCCCAC A CCUGUUUG
6468
CAAACAGG GGCTAGCTACAACGA GTGGGCAA
19374





2107
CCACACCU G UUUGCAAG
8740
CTTGCAAA GGCTAGCTACAACGA AGGTGTGG
19375





2111
ACCUGUUU G CAAGAACU
8741
AGTTCTTG GGCTAGCTACAACGA AAACAGGT
19376





2117
UUGCAAGA A CUUGGAUA
8742
TATCCAAG GGCTAGCTACAACGA TCTTGCAA
19377





2123
GAACUUGG A UACUCUUU
8743
AAAGAGTA GGCTAGCTACAACGA CCAAGTTC
19378





2125
ACUUGGAU A CUCUUUGG
1795
CCAAAGAG GGCTAGCTACAACGA ATCCAAGT
19379





2136
CUUUGGAA A UUGAAUGC
8744
GCATTCAA GGCTAGCTACAACGA TTCCAAAG
19380





2141
GAAAUUGA A UGCCACCA
8745
TGGTGGCA GGCTAGCTACAACGA TCAATTTC
19381





2143
AAUUGAAU G CCACCAUG
8746
CATGGTGG GGCTAGCTACAACGA ATTCAATT
19382





2146
UGAAUGCC A CCAUGUUC
6476
GAACATGG GGCTAGCTACAACGA GGCATTCA
19383





2149
AUGCCACC A UGUUCUCU
6478
AGAGAACA GGCTAGCTACAACGA GGTGGCAT
19384





2151
GCCACCAU G UUCUCUAA
8747
TTAGAGAA GGCTAGCTACAACGA ATGGTGGC
19385





2159
GUUCUCUA A UAGCACAA
8748
TTGTGCTA GGCTAGCTACAACGA TAGAGAAC
19386





2162
CUCUAAUA G CACAAAUG
8749
CATTTGTG GGCTAGCTACAACGA TATTAGAG
19387





2164
CUAAUAGC A CAAAUGAC
6481
GTCATTTG GGCTAGCTACAACGA GCTATTAG
19388





2168
UAGCACAA A UGACAUUU
8750
AAATGTCA GGCTAGCTACAACGA TTGTGCTA
19389





2171
CACAAAUG A CAUUUUGA
8751
TCAAAATG GGCTAGCTACAACGA CATTTGTG
19390





2173
CAAAUGAC A UUUUGAUC
6483
GATCAAAA GGCTAGCTACAACGA GTCATTTG
19391





2179
ACAUUUUG A UCAUGGAG
8752
CTCCATGA GGCTAGCTACAACGA CAAAATGT
19392





2182
UUUUGAUC A UGGAGCUU
6484
AAGCTCCA GGCTAGCTACAACGA GATCAAAA
19393





2187
AUCAUGGA G CUUAAGAA
8753
TTCTTAAG GGCTAGCTACAACGA TCCATGAT
19394





2195
GCUUAAGA A UGCAUCCU
8754
AGGATGCA GGCTAGCTACAACGA TCTTAAGC
19395





2197
UUAAGAAU G CAUCCUUG
8755
CAAGGATG GGCTAGCTACAACGA ATTCTTAA
19396





2199
AAGAAUGC A UCCUUGCA
6486
TGCAAGGA GGCTAGCTACAACGA GCATTCTT
19397





2205
GCAUCCUU G CAGGACCA
8756
TGGTCCTG GGCTAGCTACAACGA AAGGATGC
19398





2210
CUUGCAGG A CCAAGGAG
8757
CTCCTTGG GGCTAGCTACAACGA CCTGCAAG
19399





2219
CCAAGGAG A CUAUGUCU
8758
AGACATAG GGCTAGCTACAACGA CTCCTTGG
19400





2222
AGGAGACU A UGUCUGCC
1813
GGCAGACA GGCTAGCTACAACGA AGTCTCCT
19401





2224
GAGACUAU G UCUGCCUU
8759
AAGGCAGA GGCTAGCTACAACGA ATAGTCTC
19402





2228
CUAUGUCU G CCUUGCUC
8760
GAGCAAGG GGCTAGCTACAACGA AGACATAG
19403





2233
UCUGCCUU G CUCAAGAC
8761
GTCTTGAG GGCTAGCTACAACGA AAGGCAGA
19404





2240
UGCUCAAG A CAGGAAGA
8762
TCTTCCTG GGCTAGCTACAACGA CTTGAGCA
19405





2248
ACAGGAAG A CCAAGAAA
8763
TTTCTTGG GGCTAGCTACAACGA CTTCCTGT
19406





2259
AAGAAAAG A CAUUGCGU
8764
ACGCAATG GGCTAGCTACAACGA CTTTTCTT
19407





2261
GAAAAGAC A UUGCGUGG
6501
CCACGCAA GGCTAGCTACAACGA GTCTTTTC
19408





2264
AAGACAUU G CGUGGUCA
8765
TGACCACG GGCTAGCTACAACGA AATGTCTT
19409





2266
GACAUUGC G UGGUCAGG
8766
CCTGACCA GGCTAGCTACAACGA GCAATGTC
19410





2269
AUUGCGUG G UCAGGCAG
8767
CTGCCTGA GGCTAGCTACAACGA CACGCAAT
19411





2274
GUGGUCAG G CAGCUCAC
8768
GTGAGCTG GGCTAGCTACAACGA CTGACCAC
19412





2277
GUCAGGCA G CUCACAGU
8769
ACTGTGAG GGCTAGCTACAACGA TGCCTGAC
19413





2281
GGCAGCUC A CAGUCCUA
6505
TAGGACTG GGCTAGCTACAACGA GAGCTGCC
19414





2284
AGCUCACA G UCCUAGAG
8770
CTCTAGGA GGCTAGCTACAACGA TGTGAGCT
19415





2292
GUCCUAGA G CGUGUGGC
8771
GCCACACG GGCTAGCTACAACGA TCTAGGAC
19416





2294
CCUAGAGC G UGUGGCAC
8772
GTGCCACA GGCTAGCTACAACGA GCTCTAGG
19417





2296
UAGAGCGU G UGGCACCC
8773
GGGTGCCA GGCTAGCTACAACGA ACGCTCTA
19418





2299
AGCGUGUG G CACCCACG
8774
CGTGGGTG GGCTAGCTACAACGA CACACGCT
19419





2301
CGUGUGGC A CCCACGAU
6509
ATCGTGGG GGCTAGCTACAACGA GCCACACG
19420





2305
UGGCACCC A CGAUCACA
6512
TGTGATCG GGCTAGCTACAACGA GGGTGCCA
19421





2308
CACCCACG A UCACAGGA
8775
TCCTGTGA GGCTAGCTACAACGA CGTGGGTG
19422





2311
CCACGAUC A CAGGAAAC
6513
GTTTCCTG GGCTAGCTACAACGA GATCGTGG
19423





2318
CACAGGAA A CCUGGAGA
8776
TCTCCAGG GGCTAGCTACAACGA TTCCTGTG
19424





2327
CCUGGAGA A UCAGACGA
8777
TCGTCTGA GGCTAGCTACAACGA TCTCCAGG
19425





2332
AGAAUCAG A CGACAAGU
8778
ACTTGTCG GGCTAGCTACAACGA CTGATTCT
19426





2335
AUCAGACG A CAAGUAUU
8779
AATACTTG GGCTAGCTACAACGA CGTCTGAT
19427





2339
GACGACAA G UAUUGGGG
8780
CCCCAATA GGCTAGCTACAACGA TTGTCGTC
19428





2341
CGACAAGU A UUGGGGAA
1824
TTCCCCAA GGCTAGCTACAACGA ACTTGTCG
19429





2351
UGGGGAAA G CAUCGAAG
8781
CTTCGATG GGCTAGCTACAACGA TTTCCCCA
19430





2353
GGGAAAGC A UCGAAGUC
6519
GACTTCGA GGCTAGCTACAACGA GCTTTCCC
19431





2359
GCAUCGAA G UCUCAUGC
8782
GCATGAGA GGCTAGCTACAACGA TTCGATGC
19432





2364
GAAGUCUC A UGCACGGC
6521
GCCGTGCA GGCTAGCTACAACGA GAGACTTC
19433





2366
AGUCUCAU G CACGGCAU
8783
ATGCCGTG GGCTAGCTACAACGA ATGAGACT
19434





2368
UCUCAUGC A CGGCAUCU
6522
AGATGCCG GGCTAGCTACAACGA GCATGAGA
19435





2371
CAUGCACG G CAUCUGGG
8784
CCCAGATG GGCTAGCTACAACGA CGTGCATG
19436





2373
UGCACGGC A UCUGGGAA
6523
TTCCCAGA GGCTAGCTACAACGA GCCGTGCA
19437





2381
AUCUGGGA A UCCCCCUC
8785
GAGGGGGA GGCTAGCTACAACGA TCCCAGAT
19438





2391
CCCCCUCC A CAGAUCAU
6531
ATGATCTG GGCTAGCTACAACGA GGAGGGGG
19439





2395
CUCCACAG A UCAUGUGG
8786
CCACATGA GGCTAGCTACAACGA CTGTGGAG
19440





2398
CACAGAUC A UGUGGUUU
6533
AAACCACA GGCTAGCTACAACCA GATCTGTG
19441





2400
CAGAUCAU G UGGUUUAA
8787
TTAAACCA GGCTAGCTACAACGA ATGATCTG
19442





2403
AUCAUGUG G UGGAAAGA
8788
TCTTTAAA GGCTAGCTACAACGA CACATGAT
19443





2411
GUUUAAAG A UAAUGAGA
8789
TCTCATTA GGCTAGCTACAACGA CTTTAAAC
19444





2414
UAAAGAUA A UGAGACCC
8790
GGGTCTCA GGCTAGCTACAACGA TATCTTTA
19445





2419
AUAAUGAG A CCCUUCUA
8791
TACAAGGG GGCTAGCTACAACGA CTCATTAT
19446





2425
AGACCCUU G UAGAAGAC
8792
GTCTTCTA GGCTAGCTACAACGA AAGGGTCT
19447





2432
UGUAGAAG A CUCAGGCA
8793
TGCCTGAG GGCTAGCTACAACGA CTTCTACA
19448





2438
AGACUCAG G CAUUGUAU
8794
ATACAATG GGCTAGCTACAACGA CTGAGTCT
19449





2440
ACUCAGGC A UUGUAUUG
6539
CAATACAA GGCTAGCTACAACGA GCCTGACT
19450





2443
CAGGCAUU G UAUUGAAG
8795
CTTCAATA GGCTAGCTACAACGA AATGCCTG
19451





2445
GGCAUUGU A UUGAAGGA
1841
TCCTTCAA GGCTAGCTACAACGA ACAATGCC
19452





2453
AUUGAAGG A UGGGAACC
8796
GGTTCCCA GGCTAGCTACAACGA CCTTCAAT
19453





2459
GGAUGGGA A CCGGAACC
8797
GGTTCCGG GGCTAGCTACAACGA TCCCATCC
19454





2465
GAACCGGA A CCUCACUA
8798
TAGTGAGG GGCTAGCTACAACGA TCCGGTTC
19455





2470
GGAACCUC A CUAUCCGC
6543
GCGGATAG GGCTAGCTACAACGA GAGGTTCC
19456





2473
ACCUCACU A UCCGCAGA
1844
TCTGCGGA GGCTAGCTACAACGA AGTGAGGT
19457





2477
CACUAUCC G CAGAGUGA
8799
TCACTCTG GGCTAGCTACAACGA GGATAGTG
19458





2482
UCCGCAGA G UGAGGAAG
8800
CTTCCTCA GGCTAGCTACAACGA TCTGCGGA
19459





2495
GAAGGAGG A CGAAGGCC
8801
GGCCTTCG GGCTAGCTACAACGA CCTCCTTC
19460





2501
GGACGAAG G CCUCUACA
8802
TGTAGAGG GGCTAGCTACAACGA CTTCGTCC
19461





2507
AGGCCUCU A CACCUGCC
1847
GGCAGGTG GGCTAGCTACAACGA AGAGGCCT
19462





2509
GCCUCUAC A CCUGCCAG
6550
CTGGCAGG GGCTAGCTACAACGA GTAGAGGC
19463





2513
CUACACCU G CCAGGCAU
8803
ATGCCTGG GGCTAGCTACAACGA AGGTGTAG
19464





2518
CCUGCCAG G CAUGCAGU
8804
ACTGCATG GGCTAGCTACAACGA CTGGCAGG
19465





2520
UGCCAGGC A UGCAGUGU
6555
ACACTGCA GGCTAGCTACAACGA GCCTGGCA
19466





2522
CCAGGCAU G CAGUGUUC
8805
GAACACTG GGCTAGCTACAACGA ATGCCTGG
19467





2525
GGCAUGCA G UGUUCUUG
8806
CAAGAACA GGCTAGCTACAACGA TGCATGCC
19468





2527
CAUGCAGU G UUCUUGGC
8807
GCCAAGAA GGCTAGCTACAACGA ACTGCATG
19469





2534
UGUUCUUG G CUGUGCAA
8808
TTGCACAG GGCTAGCTACAACGA CAAGAACA
19470





2537
UCUUGGCU G UGCAAAAG
8809
CTTTTGCA GGCTAGCTACAACGA AGCCAAGA
19471





2539
UUGGCUGU G CAAAAGUG
8810
CACTTTTG GGCTAGCTACAACGA ACAGCCAA
19472





2545
GUGCAAAA G UGGAGGCA
8811
TGCCTCCA GGCTAGCTACAACGA TTTTGCAC
19473





2551
AAGUGGAG G CAUUUUUC
8812
GAAAAATG GGCTAGCTACAACGA CTCCACTT
19474





2553
GUGGAGGC A UUUUUCAU
6560
ATGAAAAA GGCTAGCTACAACGA GCCTCCAC
19475





2560
CAUUUUUC A UAAUAGAA
6561
TTCTATTA GGCTAGCTACAACGA GAAAAATG
19476





2563
UUUUCAUA A UAGAAGGU
8813
ACCTTCTA GGCTAGCTACAACGA TATGAAAA
19477





2570
AAUAGAAG G UGCCCAGG
8814
CCTGGGCA GGCTAGCTACAACGA CTTCTATT
19478





2572
UAGAAGGU G CCCAGGAA
8815
TTCCTGGG GGCTAGCTACAACGA ACCTTCTA
19479





2584
AGGAAAAG A CGAACUUG
8818
CAAGTTCG GGCTAGCTACAACGA CTTTTCCT
19480





2588
AAAGACGA A CUUGGAAA
8817
TTTCCAAG GGCTAGCTACAACGA TCGTCTTT
19481





2596
ACUUGGAA A UCAUUAUU
8818
AATAATGA GGCTAGCTACAACGA TTCCAAGT
19482





2599
UGGAAAUC A UUAUUCUA
6568
TAGAATAA GGCTAGCTACAACGA GATTTCCA
19483





2602
AAAUCAUU A UUCUAGUA
1861
TACTAGAA GGCTAGCTACAACGA AATGATTT
19484





2608
UUAUUCUA G UAGGCACG
8819
CGTGCCTA GGCTAGCTACAACGA TAGAATAA
19485





2612
UCUAGUAG G CACGGCGG
8820
CCGCCGTG GGCTAGCTACAACGA CTACTAGA
19486





2614
UAGUAGGC A CGGCGGUG
8821
CACCGCCG GGCTAGCTACAACGA GCCTACTA
19487





2617
UAGGCACG G CGGUGAUU
8822
AATCACCG GGCTAGCTACAACGA CGTGCCTA
19488





2620
GCACGGCG G UGAUUGCC
8823
GGCAATCA GGCTAGCTACAACGA CGCCGTGC
19489





2623
CGGCGGUG A UUGCCAUG
8824
CATGGCAA GGCTAGCTACAACGA CACCGCCG
19490





2626
CGGUGAUU G CCAUGUUC
8825
GAACATCG GGCTAGCTACAACGA AATCACCG
19491





2629
UGAUUGCC A UGUUCUUC
6570
GAAGAACA GGCTAGCTACAACGA GGCAATCA
19492





2631
AUUGCCAU G UUCUUCUG
8826
CAGAAGAA GGCTAGCTACAACGA ATGGCAAT
19493





2640
UUCUUCUG G CUACUUCU
8827
ACAAGTAG GGCTAGCTACAACGA CAGAACAA
19494





2643
UUCUGGCU A CUUCUUGU
1871
ACAAGAAG GGCTAGCTACAACGA AGCCACAA
19495





2650
UACUUCUU G UCAUCAUC
8828
GATGATGA GGCTAGCTACAACGA AAGAACTA
19496





2653
UUCUUGUC A UCAUCCUA
8576
TAGGATGA GGCTAGCTACAACGA GACAAGAA
19497





2656
UUGUCAUC A UCCUACGG
8829
CCCTAGGA GGCTAGCTACAACGA GATGACAA
19498





2661
AUCAUCCU A CGGACCGU
8830
ACGGTCCG GGCTAGCTACAACGA AGGATGAT
19499





2665
UCCUACGG A CCGUUAAG
8831
CTTAACGG GGCTAGCTACAACGA CCCTAGGA
19500





2668
UACCCACC G UUAAGCGG
8832
CCGCTTAA GGCTAGCTACAACGA CGTCCGTA
19501





2673
ACCCUUAA G CCGGCCAA
8833
TTCGCCCG GGCTAGCTACAACGA TTAACGGT
19502





2677
UUAACCCG G CCAAUCGA
8834
TCCATTGG GGCTAGCTACAACGA CCGCTTAA
19503





2681
GCGGGCCA A UGGAGGGG
8835
CCCCTCCA GGCTAGCTACAACGA TGGCCCGC
19504





2691
GCACGGCA A CUGAACAC
8836
GTCTTCAG GGCTAGCTACAACGA TCCCCTCC
19505





2698
AACUGAAG A CAGGCUAC
8837
GTAGCCTG GGCTAGCTACAACGA CTTCAGTT
19506





2702
GAAGACAG G CUACUUGU
8838
ACAAGTAG GGCTAGCTACAACGA CTCTCTTC
19507





2705
GACAGGCU A CUUGUCCA
1881
TGGACAAG GGCTAGCTACAACGA ACCCTGTC
19508





2709
GGCUACUU G UCCAUCGU
8839
ACGATGCA GGCTAGCTACAACGA AACTAGCC
19509





2713
ACUUCUCC A UCGUCAUC
6588
CATCACCA GGCTAGCTACAACGA GGACAAGT
19510





2716
UCUCCAUC G UCAUGGAU
8840
ATCCATCA GGCTAGCTACAACGA GATGGACA
19511





2719
CCAUCGUC A UGGAUCCA
8589
TGCATCCA GGCTAGCTACAACGA CACGATGC
19512





2723
CCUCAUCC A UCCACAUG
8841
CATCTGCA GGCTAGCTACAACGA CCATCACC
19513





2729
CCAUCCAG A UGAACUCC
8842
CGACTTCA GGCTAGCTACAACGA CTGCATCC
19514





2733
CCAGAUGA A CUCCCAUU
8843
AATCCCAC GGCTAGCTACAACGA TCATCTGG
19515





2739
GAACUCCC A CUGGAUGA
8595
TCATCCAA GGCTAGCTACAACGA CCCAGTTC
19516





2744
CCCAUUGG A UGAACAUU
8844
AATCTTCA GGCTAGCTACAACGA CCAATGGC
19517





2748
UUGCAUGA A CACUCUGA
8845
TCACAATG GGCTAGCTACAACGA TCATCCAA
19518





2750
GGAUGAAC A UUCUGAAC
6596
GTTCACAA GGCTAGCTACAACGA GTTCATCC
19519





2753
UGAACAUU G UGAACCAC
8848
GTCCTTCA GGCTAGCTACAACGA AATGTTCA
19520





2757
CAUUGUGA A CCACUGCC
8847
CGCACTCC GGCTAGCTACAACGA TCACAATC
19521





2760
UGUCAACG A CUGCCUUA
8848
TAAGCCAG GGCTAGCTACAACGA CGTTCACA
19522





2763
CAACGACU G CCUUAUCA
8849
TCATAACC GGCTAGCTACAACGA AGTCGTTC
19523





2768
ACUGCCUU A UGAUGCCA
1891
TGGCATCA GGCTAGCTACAACGA AAGCCACT
19524





2771
CCCUUAUC A UCCCAGCA
8850
TGCTCGCA GGCTAGCTACAACGA CATAACGC
19525





2773
CUUAUGAU G CCAGCAAA
8851
TTTCCTGC GGCTAGCTACAACGA ATCATAAG
19526





2777
UGAUGCCA G CAAAUGGG
8852
CCCATTTG GGCTAGCTACAACGA TGGCATCA
19527





2781
GCCAGCAA A UGGGAAUU
8853
AATTCCCA GGCTAGCTACAACGA TTGCTGGC
19528





2787
AAAUGGGA A UUCCCCAG
8854
CTGGGGAA GGCTAGCTACAACGA TCCCATTT
19529





2798
CCCCAGAG A CCGGCUGA
8855
TCAGCCGG GGCTAGCTACAACGA CTCTGGGG
19530





2802
AGAGACCG G CUGAAGCU
8856
AGCTTCAG GGCTAGCTACAACGA CGGTCTCT
19531





2808
CGGCUGAA G CUAGGUAA
8857
TTACCTAG GGCTAGCTACAACGA TTCAGCCG
19532





2813
GAAGCUAG G UAAGCCUC
8858
GAGGCTTA GGCTAGCTACAACGA CTAGCTTC
19533





2817
CUAGGUAA G CCUCUUGG
8859
CCAAGAGG GGCTAGCTACAACGA TTACCTAG
19534





2825
GCCUCUUG G GCCUGGUG
8860
CACCACGG GGCTAGCTACAACGA CAAGAGGC
19535





2828
UCUUGGCC G UGGUGCCU
8881
AGGCACCA GGCTAGCTACAACGA GGCCAAGA
19536





2831
UCGCCGUG G UGCCUUUG
8862
CAAAGGCA GGCTAGCTACAACGA CACGGCCA
19537





2833
GCCGUGGU G CCUUUGGC
8863
GCCAAAGG GGCTAGCTACAACGA ACCACGGC
19538





2840
UGCCUUUG G CCAAGUGA
8884
TCACTTGG GGCTAGCTACAACGA CAAAGGCA
19539





2845
UUGGCCAA G UGAUUGAA
8865
TTCAATCA GGCTAGCTACAACGA TTGGCCAA
19540





2848
GCCAAGUG A UUGAAGCA
8866
TGCTTCAA GGCTAGCTACAACGA CACTTGGC
19541





2854
UGAUUGAA G CAGAUGCC
8867
GGCATCTG GGCTAGCTACAACGA TTCAATCA
19542





2858
UGAAGCAG A UGCCUUUG
8868
CAAAGGCA GGCTAGCTACAACGA CTCCTTCA
19543





2860
AAGCAGAU G CCUUUGGA
8869
TCCAAACG GGCTAGCTACAACGA ATCTCCTT
19544





2869
CCUUUGGA A UUCACAAG
8870
CTTCTCAA GGCTAGCTACAACGA TCCAAAGC
19545





2873
UGGAAUUG A CAAGACAG
8871
CTGTCTTG GGCTAGCTACAACGA CAATTCCA
19546





2878
UUGACAAG A CAGCAACU
8872
AGTTGCTG GGCTAGCTACAACGA CTTGTCAA
19547





2881
ACAAGACA G CAACUUGC
8873
GCAAGTTG GGCTAGCTACAACGA TGTCTTGT
19548





2884
ACACACCA A CUUGCAGG
8874
CCTCCAAG GGCTAGCTACAACGA TGCTGTCT
19549





2888
ACCAACUU G CAGGACAC
8875
CTGTCCTG GGCTAGCTACAACGA AAGTTGCT
19550





2893
CUUGCAGG A CACUAGCA
8876
TCCTACTC GGCTAGCTACAACGA CCTCCAAG
19551





2896
GCAGGACA G UAGCAGUC
8877
GACTCCTA GGCTAGCTACAACGA TCTCCTGC
19552





2899
GGACAGUA G CAGUCAAA
8878
TTTCACTC GGCTAGCTACAACGA TACTGTCC
19553





2902
CACUAGCA G UCAAAAUG
8879
CATTTTGA GGCTAGCTACAACGA TGCTACTC
19554





2908
CAGUCAAA A UGUUGAAA
8880
TTTCAACA GGCTAGCTACAACGA TTTGACTG
19555





2910
GUCAAAAU G UUGAAAGA
8881
TCTTTCAA GGCTAGCTACAACGA ATTTTGAC
19556





2923
AAGAAGGA G CAACACAC
8882
CTGTGTTG GGCTAGCTACAACGA TCCTTCTT
19557





2926
AAGGAGCA A CACACAGU
8883
ACTGTGTG GGCTAGCTACAACGA TCCTCCTT
19558





2928
GGAGCAAC A CACAGUGA
6631
TCACTCTC GGCTAGCTACAACGA GTTGCTCC
19559





2930
AGCAACAC A CAGUGAGC
6632
GCTCACTG GGCTAGCTACAACGA GTGTTGCT
19560





2933
AACACACA G UGAGCAUC
8884
GATGCTCA GGCTAGCTACAACGA TGTGTGTT
19561





2937
CACAGUGA G CAUCGAGC
8885
GCTCGATG GGCTAGCTACAACGA TCACTGTG
19562





2939
CACUGAGC A UCCACCUC
6634
GAGCTCGA GGCTAGCTACAACGA GCTCACTG
19563





2944
ACCAUCCA G CUCUCAUG
8886
CATGAGAG GGCTAGCTACAACGA TCCATGCT
19564





2950
GACCUCUC A UGUCUGAA
6637
TTCAGACA GGCTAGCTACAACGA GACAGCTC
19565





2952
CCUCUCAU G UCUCAACU
8887
ACTTCAGA GGCTAGCTACAACGA ATCACAGC
19566





2958
AUGUCUGA A CUCAAGAU
8888
ATCTTGAG GGCTAGCTACAACGA TCACACAT
19567





2965
AACUCAAG A UCCUCAUU
8889
AATCACGA GGCTAGCTACAACGA CTTCAGTT
19568





2971
ACAUCCUC A UUCAUAUU
6643
AATATGAA GGCTAGCTACAACGA GAGGATCT
19569





2975
CCUCAUUC A UAUUCGUC
6644
GACCAATA GGCTAGCTACAACGA GAATCACG
19570





2977
UCAUUCAU A UUCCUCAC
1917
CTCACCAA GGCTAGCTACAACGA ATGAATGA
19571





2981
UCAUAUUG G UCACCAUC
8890
GATCGTGA GGCTAGCTACAACGA CAATATGA
19572





2984
UAUUGGUC A CCAUCUCA
6645
TCACATGG GGCTAGCTACAACGA CACCAATA
19573





2987
UCGUCACC A UCUCAAUG
6647
CATTCACA GGCTAGCTACAACGA CGTGACCA
19574





2993
CCAUCUCA A UGUGGUCA
8891
TGACCACA GGCTAGCTACAACGA TCACATGC
19575





2995
AUCUCAAU G UGGUCAAC
8892
GTTGACCA GGCTAGCTACAACGA ATTGAGAT
19576





2998
UCAAUGUG G UCAACCUU
8893
AAGGTTGA GGCTAGCTACAACGA CACATTGA
19577





3002
UGUGGUCA A CCUUCUAG
8894
CTAGAAGG GGCTAGCTACAACGA TGACCACA
19578





3011
CCUUCUAG G UGCCUGUA
8895
TACAGGCA GGCTAGCTACAACGA CTAGAAGG
19579





3013
UUCUAGGU G CCUGUACC
8896
GGTACAGG GGCTAGCTACAACGA ACCTAGAA
19580





3017
AGGUGCCU G UACCAAGC
8897
GCTTGGTA GGCTAGCTACAACGA AGGCACCT
19581





3019
GUGCCUGU A CCAAGCCA
1926
TGGCTTGG GGCTAGCTACAACGA ACAGGCAC
19582





3024
UGUACCAA G CCAGGAGG
8898
CCTCCTGG GGCTAGCTACAACGA TTGGTACA
19583





3033
CCAGGAGG G CCACUCAU
8899
ATGAGTGG GGCTAGCTACAACGA CCTCCTGG
19584





3036
GGAGGGCC A CUCAUGGU
6661
ACCATGAG GGCTAGCTACAACGA GGCCCTCC
19585





3040
GGCCACUC A UGGUGAUU
6663
AATCACCA GGCTAGCTACAACGA GAGTGGCC
19586





3043
CACUCAUG G UGAUUGUG
8900
CACAATCA GGCTAGCTACAACGA CATGAGTG
19587





3046
UCAUGGUG A UUGUGGAA
8901
TTCCACAA GGCTAGCTACAACGA CACCATGA
19588





3049
UGGUGAUU G UGGAAUUC
8902
GAATTCCA GGCTAGCTACAACGA AATCACCA
19589





3054
AUUGUGGA A UUCUGCAA
8903
TTGCAGAA GGCTAGCTACAACGA TCCACAAT
19590





3059
GGAAUUCU G CAAAUUUG
8904
CAAATTTG GGCTAGCTACAACGA AGAATTCC
19591





3063
UUCUGCAA A UUUGGAAA
8905
TTTCCAAA GGCTAGCTACAACGA TTGCAGAA
19592





3071
AUUUGGAA A CCUGUCCA
8906
TGGACAGG GGCTAGCTACAACGA TTCCAAAT
19593





3075
GGAAACCU G UCCACUUA
8907
TAAGTGGA GGCTAGCTACAACGA AGGTTTCC
19594





3079
ACCUGUCC A CUUACCUG
6669
CAGGTAAG GGCTAGCTACAACGA GGACAGGT
19595





3083
GUCCACUU A CCUGAGGA
1935
TCCTCAGG GGCTAGCTACAACGA AAGTGGAC
19596





3092
CCUGAGGA G CAAGAGAA
8908
TTCTCTTG GGCTAGCTACAACGA TCCTCAGG
19597





3101
CAAGAGAA A UGAAUUUG
8909
CAAATTCA GGCTAGCTACAACGA TTCTCTTG
19598





3105
AGAAAUGA A UUUGUCCC
8910
GGGACAAA GGCTAGCTACAACGA TCATTTCT
19599





3109
AUGAAUUU G UCCCCUAC
8911
GTAGGGGA GGCTAGCTACAACGA AAATTCAT
19600





3116
UGUCCCCU A CAAGACCA
1939
TGGTCTTG GGCTAGCTACAACGA AGGGGACA
19601





3121
CCUACAAG A CCAAAGGG
8912
CCCTTTGG GGCTAGCTACAACGA CTTGTAGG
19602





3130
CCAAAGGG G CACGAUUC
8913
GAATCGTG GGCTAGCTACAACGA CCCTTTGG
19603





3132
AAAGGGGC A CGAUUCCG
6681
CGGAATCG GGCTAGCTACAACGA GCCCCTTT
19604





3135
GGGGCACG A UUCCGUCA
8914
TGACGGAA GGCTAGCTACAACGA CGTGCCCC
19605





3140
ACGAUUCC G UCAAGGGA
8915
TCCCTTGA GGCTAGCTACAACGA GGAATCGT
19606





3152
AGGGAAAG A CUACGUUG
8916
CAACGTAG GGCTAGCTACAACGA CTTTCCCT
19607





3155
GAAAGACU A CGUUGGAG
1943
CTCCAACG GGCTAGCTACAACGA AGTCTTTC
19608





3157
AAGACUAC G UUGGAGCA
8917
TGCTCCAA GGCTAGCTACAACGA GTAGTCTT
19609





3163
ACGUUGGA G CAAUCCCU
8918
AGGGATTG GGCTAGCTACAACGA TCCAACGT
19610





3166
UUGGAGCA A UCCCUGUG
8919
CACAGGGA GGCTAGCTACAACGA TGCTCCAA
19611





3172
CAAUCCCU G UGGAUCUG
8920
CAGATCCA GGCTAGCTACAACGA AGGGATTG
19612





3176
CCCUGUGG A UCUGAAAC
8921
GTTTCAGA GGCTAGCTACAACGA CCACAGGG
19613





3183
GAUCUGAA A CGGCGCUU
8922
AAGCGCCG GGCTAGCTACAACGA TTCAGATC
19614





3186
CUGAAACG G CGCUUGGA
8923
TCCAAGCG GGCTAGCTACAACGA CGTTTCAG
19615





3188
GAAACGGC G CUUGGACA
8924
TGTCCAAG GGCTAGCTACAACGA GCCGTTTC
19616





3194
GCGCUUGG A CAGCAUCA
8925
TGATGCTG GGCTAGCTACAACGA CCAAGCGC
19617





3197
CUUGGACA G CAUCACCA
8926
TGGTGATG GGCTAGCTACAACGA TGTCCAAG
19618





3199
UGGACAGC A UCACCAGU
6692
ACTGGTGA GGCTAGCTACAACGA GCTGTCCA
19619





3202
ACAGCAUC A CCAGUAGC
6693
GCTACTGG GGCTAGCTACAACGA GATGCTGT
19620





3206
CAUCACCA G UAGCCAGA
8927
TCTGGCTA GGCTAGCTACAACGA TGGTGATG
19621





3209
CACCAGUA G CCAGAGCU
8928
AGCTCTGG GGCTAGCTACAACGA TACTGGTG
19622





3215
UAGCCAGA G CUCAGCCA
8929
TGGCTGAG GGCTAGCTACAACGA TCTGGCTA
19623





3220
AGAGCUCA G CCAGCUCU
8930
AGAGCTGG GGCTAGCTACAACGA TGAGCTCT
19624





3224
CUCAGCCA G CUCUGGAU
8931
ATCCAGAG GGCTAGCTACAACGA TGGCTGAG
19625





3231
AGCUCUGG A UUUGUGGA
8932
TCCACAAA GGCTAGCTACAACGA CCAGAGCT
19626





3235
CUGGAUUU G UGGAGGAG
8933
CTCCTCCA GGCTAGCTACAACGA AAATCCAG
19627





3246
GAGGAGAA G UCCCUCAG
8934
CTGAGGGA GGCTAGCTACAACGA TTCTCCTC
19628





3254
GUCCCUCA G UGAUGUAG
8935
CTACATCA GGCTAGCTACAACGA TGAGGGAC
19629





3257
CCUCAGUG A UGUAGAAG
8936
CTTCTACA GGCTAGCTACAACGA CACTGAGG
19630





3259
UCAGUGAU G UAGAAGAA
8937
TTCTTCTA GGCTAGCTACAACGA ATCACTGA
19631





3274
AAGAGGAA G CUCCUGAA
8938
TTCAGGAG GGCTAGCTACAACGA TTCCTCTT
19632





3284
UCCUGAAG A UCUGUAUA
8939
TATACAGA GGCTAGCTACAACGA CTTCAGGA
19633





3288
GAAGAUCU G UAUAAGGA
8940
TCCTTATA GGCTAGCTACAACGA AGATCTTC
19634





3290
AGAUCUGU A UAAGGACU
1959
AGTCCTTA GGCTAGCTACAACGA ACAGATCT
19635





3296
GUAUAAGG A CUUCCUGA
8941
TCAGGAAG GGCTAGCTACAACGA CCTTATAC
19636





3304
ACUUCCUG A CCUUGGAG
8942
CTCCAAGG GGCTAGCTACAACGA CAGGAAGT
19637





3312
ACCUUGGA G CAUCUCAU
8943
ATGAGATG GGCTAGCTACAACGA TCCAAGGT
19638





3314
CUUGGAGC A UCUCAUCU
6717
AGATGAGA GGCTAGCTACAACGA GCTCCAAG
19639





3319
AGCAUCUC A UCUGUUAC
6719
GTAACAGA GGCTAGCTACAACGA GAGATGCT
19640





3323
UCUCAUCU G UUACAGCU
8944
AGCTGTAA GGCTAGCTACAACGA AGATGAGA
19641





3326
CAUCUGUU A CAGCUUCC
1968
GGAAGCTG GGCTAGCTACAACGA AACAGATG
19642





3329
CUGUUACA G CUUCCAAG
8945
CTTGGAAG GGCTAGCTACAACGA TGTAACAG
19643





3337
GCUUCCAA G UGGCUAAG
8946
CTTAGCCA GGCTAGCTACAACGA TTGGAAGC
19644





3340
UCCAAGUG G CUAAGGGC
8947
GCCCTTAG GGCTAGCTACAACGA CACTTGGA
19645





3347
GGCUAAGG G CAUGGAGU
8948
ACTCCATG GGCTAGCTACAACGA CCTTAGCC
19646





3349
CUAAGGGC A UGGAGUUC
6726
GAACTCCA GGCTAGCTACAACGA GCCCTTAG
19647





3354
GGCAUGGA G UUCUUGGC
8949
GCCAAGAA GGCTAGCTACAACGA TCCATGCC
19648





3361
AGUUCUUG G CAUCGCGA
8950
TCGCGATG GGCTAGCTACAACGA CAAGAACT
19649





3363
UUCUUGGC A UCGCGAAA
6728
TTTCGCGA GGCTAGCTACAACGA GCCAAGAA
19650





3366
UUGGCAUC G CGAAAGUG
8951
CACTTTCG GGCTAGCTACAACGA GATGCCAA
19651





3372
UCGCGAAA G UGUAUCCA
8952
TGGATACA GGCTAGCTACAACGA TTTCGCGA
19652





3374
GCGAAAGU G UAUCCACA
8953
TGTGGATA GGCTAGCTACAACGA ACTTTCGC
19653





3376
GAAAGUGU A UCCACAGG
1976
CCTGTGGA GGCTAGCTACAACGA ACACTTTC
19654





3380
GUGUAUCC A CAGGGACC
6730
GGTCCCTG GGCTAGCTACAACGA GGATACAC
19655





3386
CCACAGGG A CCUGGCGG
8954
CCGCCAGG GGCTAGCTACAACGA CCCTGTGG
19656





3391
GGGACCUG G CGGCACGA
8955
TCGTGCCG GGCTAGCTACAACGA CAGGTCCC
19657





3394
ACCUGGCG G CACGAAAU
8956
ATTTCGTG GGCTAGCTACAACGA CGCCAGGT
19658





3396
CUGGCGGC A CGAAAUAU
6734
ATATTTCG GGCTAGCTACAACGA GCCGCCAG
19659





3401
GGCACGAA A UAUCCUCU
8957
AGAGGATA GGCTAGCTACAACGA TTCGTGCC
19660





3403
CACGAAAU A UCCUCUUA
1978
TAAGAGGA GGCTAGCTACAACGA ATTTCGTG
19661





3411
AUCCUCUU A UCGGAGAA
1982
TTCTCCGA GGCTAGCTACAACGA AAGAGGAT
19662





3422
GGAGAAGA A CGUGGUUA
8958
TAACCACG GGCTAGCTACAACGA TCTTCTCC
19663





3424
AGAAGAAC G UGGUUAAA
8959
TTTAACCA GGCTAGCTACAACGA GTTCTTCT
19664





3427
AGAACGUG G UUAAAAUC
8960
GATTTTAA GGCTAGCTACAACGA CACGTTCT
19665





3433
UGGUUAAA A UCUGUGAC
8961
GTCACAGA GGCTAGCTACAACGA TTTAACCA
19666





3437
UAAAAUCU G UGACUUUG
8962
CAAAGTCA GGCTAGCTACAACGA AGATTTTA
19667





3440
AAUCUGUG A CUUUGGCU
8963
AGCCAAAG GGCTAGCTACAACGA CACAGATT
19668





3446
UGACUUUG G CUUGGCCC
8964
GGGCCAAG GGCTAGCTACAACGA CAAAGTCA
19669





3451
UUGGCUUG G CCCGGGAU
8965
ATCCCGGG GGCTAGCTACAACGA CAAGCCAA
19670





3458
GGCCCGGG A UAUUUAUA
8966
TATAAATA GGCTAGCTACAACGA CCCGGGCC
19671





3460
CCCGGGAU A UUUAUAAA
1990
TTTATAAA GGCTAGCTACAACGA ATCCCGGG
19672





3464
GGAUAUUU A UAAAGAUC
1993
GATCTTTA GGCTAGCTACAACGA AAATATCC
19673





3470
UUAUAAAG A UCCAGAUU
8967
AATCTGGA GGCTAGCTACAACGA CTTTATAA
19674





3476
AGAUCCAG A UUAUGUCA
8968
TGACATAA GGCTAGCTACAACGA CTGGATCT
19675





3479
UCCAGAUU A UGUCAGAA
1997
TTCTGACA GGCTAGCTACAACGA AATCTGGA
19676





3481
CAGAUUAU G UCAGAAAA
8969
TTTTCTGA GGCTAGCTACAACGA ATAATCTG
19677





3494
AAAAGGAG A UGCUCGCC
8970
GGCGAGCA GGCTAGCTACAACGA CTCCTTTT
19678





3496
AAGGAGAU G CUCGCCUC
8971
GAGGCGAG GGCTAGCTACAACGA ATCTCCTT
19679





3500
AGAUGCUC G CCUCCCUU
8972
AAGGGAGG GGCTAGCTACAACGA GAGCATCT
19680





3513
CCUUUGAA A UGGAUGGC
8973
GCCATCCA GGCTAGCTACAACGA TTCAAAGG
19681





3517
UGAAAUGG A UGGCCCCA
8974
TGGGGCCA GGCTAGCTACAACGA CCATTTCA
19682





3520
AAUGGAUG G CCCCAGAA
8975
TTCTGGGG GGCTAGCTACAACGA CATCCATT
19683





3529
CCCCAGAA A CAAUUUUU
8976
AAAAATTG GGCTAGCTACAACGA TTCTGGGG
19684





3532
CAGAAACA A UUUUUGAC
8977
GTCAAAAA GGCTAGCTACAACGA TGTTTCTG
19685





3539
AAUUUUUG A CAGAGUGU
8978
ACACTCTG GGCTAGCTACAACGA CAAAAATT
19686





3544
UUGACAGA G UGUACACA
8979
TGTGTACA GGCTAGCTACAACGA TCTGTCAA
19687





3546
GACAGAGU G UACACAAU
8980
ATTGTGTA GGCTAGCTACAACGA ACTCTGTC
19688





3548
CAGAGUGU A CACAAUCC
2007
GGATTGTG GGCTAGCTACAACGA ACACTCTG
19689





3550
GAGUGUAC A CAAUCCAG
6758
CTGGATTG GGCTAGCTACAACGA GTACACTC
19690





3553
UGUACACA A UCCAGAGU
8981
ACTCTGGA GGCTAGCTACAACGA TGTGTACA
19691





3560
AAUCCAGA G UGACGUCU
8982
AGACGTCA GGCTAGCTACAACGA TCTGGATT
19692





3563
CCAGAGUG A CGUCUGGU
8983
ACCAGACG GGCTAGCTACAACGA CACTCTGG
19693





3565
AGAGUGAC G UCUGGUCU
8984
AGACCAGA GGCTAGCTACAACGA GTCACTCT
19694





3570
GACGUCUG G UCUUUUGG
8985
CCAAAAGA GGCTAGCTACAACGA CAGACGTC
19695





3578
GUCUUUUG G UGUUUUGC
8986
GCAAAACA GGCTAGCTACAACGA CAAAAGAC
19696





3580
CUUUUGGU G UUUUGCUG
8987
CAGCAAAA GGCTAGCTACAACGA ACCAAAAG
19697





3585
GGUGUUUU G CUGUGGGA
8988
TCCCACAG GGCTAGCTACAACGA AAAACACC
19698





3588
GUUUUGCU G UGGGAAAU
8989
ATTTCCCA GGCTAGCTACAACGA AGCAAAAC
19699





3595
UGUGGGAA A UAUUUUCC
8990
GGAAAATA GGCTAGCTACAACGA TTCCCACA
19700





3597
UGGGAAAU A UUUUCCUU
2017
AAGGAAAA GGCTAGCTACAACGA ATTTCCCA
19701





3608
UUCCUUAG G UGCUUCUC
8991
GAGAAGCA GGCTAGCTACAACGA CTAAGGAA
19702





3610
CCUUAGGU G CUUCUCCA
8992
TGGAGAAG GGCTAGCTACAACGA ACCTAAGG
19703





3618
GCUUCUCC A UAUCCUGG
6770
CCAGGATA GGCTAGCTACAACGA GGAGAAGC
19704





3620
UUCUCCAU A UCCUGGGG
2027
CCCCAGGA GGCTAGCTACAACGA ATGGAGAA
19705





3628
AUCCUGGG G UAAAGAUU
8993
AATCTTTA GGCTAGCTACAACGA CCCAGGAT
19706





3634
GGGUAAAG A UUGAUGAA
8994
TTCATCAA GGCTAGCTACAACGA CTTTACCC
19707





3638
AAAGAUUG A UGAAGAAU
8995
ATTCTTCA GGCTAGCTACAACGA CAATCTTT
19708





3645
GAUGAAGA A UUUUGUAG
8996
CTACAAAA GGCTAGCTACAACGA TCTTCATC
19709





3650
AGAAUUUU G UAGGCGAU
8997
ATCGCCTA GGCTAGCTACAACGA AAAATTCT
19710





3654
UUUUGUAG G CGAUUGAA
8998
TTCAATCG GGCTAGCTACAACGA CTACAAAA
19711





3657
UGUAGGCG A UUGAAAGA
8999
TCTTTCAA GGCTAGCTACAACGA CGCCTACA
19712





3670
AAGAAGGA A CUAGAAUG
9000
CATTCTAG GGCTAGCTACAACGA TCCTTCTT
19713





3676
GAACUAGA A UGAGGGCC
9001
GGCCCTCA GGCTAGCTACAACGA TCTAGTTC
19714





3682
GAAUGAGG G CCCCUGAU
9002
ATCAGGGG GGCTAGCTACAACGA CCTCATTC
19715





3689
GGCCCCUG A UUAUACUA
9003
TAGTATAA GGCTAGCTACAACGA CAGGGGCC
19716





3692
CCCUGAUU A UACUACAC
2038
GTGTAGTA GGCTAGCTACAACGA AATCAGGG
19717





3694
CUGAUUAU A CUACACCA
2039
TGGTGTAG GGCTAGCTACAACGA ATAATCAG
19718





3697
AUUAUACU A CACCAGAA
2040
TTCTGGTG GGCTAGCTACAACGA AGTATAAT
19719





3699
UAUACUAC A CCAGAAAU
6779
ATTTCTGG GGCTAGCTACAACGA GTAGTATA
19720





3706
CACCAGAA A UGUACCAG
9004
CTGGTACA GGCTAGCTACAACGA TTCTGGTG
19721





3708
CCAGAAAU G UACCAGAC
9005
GTCTGGTA GGCTAGCTACAACGA ATTTCTGG
19722





3710
AGAAAUGU A CCAGACCA
2041
TGGTCTGG GGCTAGCTACAACGA ACATTTCT
19723





3715
UGUACCAG A CCAUGCUG
9006
CAGCATGG GGCTAGCTACAACGA CTGGTACA
19724





3718
ACCAGACC A UGCUGGAC
6785
GTCCAGCA GGCTAGCTACAACGA GGTCTGGT
19725





3720
CAGACCAU G CUGGACUG
9007
CAGTCCAG GGCTAGCTACAACGA ATGGTCTG
19726





3725
CAUGCUGG A CUGCUGGC
7740
GCCAGCAG GGCTAGCTACAACGA CCAGCATG
17305





3728
GCUGGACU G CUGGCACG
9008
CGTGCCAG GGCTAGCTACAACGA AGTCCAGC
19727





3732
GACUGCUG G CACGGGGA
9009
TCCCCGTG GGCTAGCTACAACGA CAGCAGTC
19728





3734
CUGCUGGC A CGGGGAGC
6788
GCTCCCCG GGCTAGCTACAACGA GCCAGCAG
19729





3741
CACGGGGA G CCCAGUCA
9010
TGACTGGG GGCTAGCTACAACGA TCCCCGTG
19730





3746
GGAGCCCA G UCAGAGAC
9011
GTCTCTGA GGCTAGCTACAACGA TGGGCTCC
19731





3753
AGUCAGAG A CCCACGUU
9012
AACGTGGG GGCTAGCTACAACGA CTCTGACT
19732





3757
AGAGACCC A CGUUUUCA
6795
TGAAAACG GGCTAGCTACAACGA GGGTCTCT
19733





3759
AGACCCAC G UUUUCAGA
9013
TCTGAAAA GGCTAGCTACAACGA GTGGGTCT
19734





3768
UUUUCAGA G UUGGUGGA
9014
TCCACCAA GGCTAGCTACAACGA TCTGAAAA
19735





3772
CAGAGUUG G UGGAACAU
9015
ATGTTCCA GGCTAGCTACAACGA CAACTCTG
19736





3777
UUGGUGGA A CAUUUGGG
9016
CCCAAATG GGCTAGCTACAACGA TCCACCAA
19737





3779
GGUGGAAC A UUUGGGAA
6797
TTCCCAAA GGCTAGCTACAACGA GTTCCACC
19738





3788
UUUGGGAA A UCUCUUGC
9017
GCAAGAGA GGCTAGCTACAACGA TTCCCAAA
19739





3795
AAUCUCUU G CAAGCUAA
9018
TTAGCTTG GGCTAGCTACAACGA AAGAGATT
19740





3799
UCUUGCAA G CUAAUGCU
9019
AGCATTAG GGCTAGCTACAACGA TTGCAAGA
19741





3803
GCAAGCUA A UGCUCAGC
9020
GCTGAGCA GGCTAGCTACAACGA TAGCTTGC
19742





3805
AAGCUAAU G CUCAGCAG
9021
CTGCTGAG GGCTAGCTACAACGA ATTAGCTT
19743





3810
AAUGCUCA G CAGGAUGG
9022
CCATCCTG GGCTAGCTACAACGA TGAGCATT
19744





3815
UCAGCAGG A UGGCAAAG
9023
CTTTGCCA GGCTAGCTACAACGA CCTGCTGA
19745





3818
GCAGGAUG G CAAAGACU
9024
AGTCTTTG GGCTAGCTACAACGA CATCCTGC
19746





3824
UGGCAAAG A CUACAUUG
9025
CAATGTAG GGCTAGCTACAACGA CTTTGCCA
19747





3827
CAAAGACU A CAUUGUUC
2055
GAACAATG GGCTAGCTACAACGA AGTCTTTG
19748





3829
AAGACUAC A UUGUUCUU
6807
AAGAACAA GGCTAGCTACAACGA GTAGTCTT
19749





3832
ACUACAUU G UUCUUCCG
9026
CGGAAGAA GGCTAGCTACAACGA AATGTAGT
19750





3841
UUCUUCCG A UAUCAGAG
9027
CTCTGATA GGCTAGCTACAACGA CGGAAGAA
19751





3843
CUUCCGAU A UCAGAGAC
2061
GTCTCTGA GGCTAGCTACAACGA ATCGGAAG
19752





3850
UAUCAGAG A CUUUGAGC
9028
GCTCAAAG GGCTAGCTACAACGA CTCTGATA
19753





3857
GACUUUGA G CAUGGAAG
9029
CTTCCATG GGCTAGCTACAACGA TCAAAGTC
19754





3859
CUUUGAGC A UGGAAGAG
6812
CTCTTCCA GGCTAGCTACAACGA GCTCAAAG
19755





3869
GCAAGAGC A UUCUCGAC
9030
GTCCAGAA GGCTAGCTACAACGA CCTCTTCC
19756





3876
GAUUCUGG A CUCUCUCU
9031
AGAGAGAG GGCTAGCTACAACGA CCAGAATC
19757





3885
CUCUCUCU G CCUACCUC
9032
GAGGTACG GGCTAGCTACAACGA ACAGACAG
19758





3889
CUCUGCCU A CCUCACCU
2070
AGGTGAGG GGCTAGCTACAACGA AGGCAGAG
19759





3894
CCUACCUC A CCUGUUUC
6822
GAAACAGG GGCTAGCTACAACGA GAGGTAGG
19760





3898
CCUCACCU G UUUCCUGU
9033
ACAGCAAA GGCTAGCTACAACGA AGCTCAGC
19761





3905
UGUUUCCU G UAUCGAGG
9034
CCTCCATA GGCTAGCTACAACGA ACGAAACA
19762





3907
UUUCCUGU A UGGAGGAG
2075
CTCCTCCA GGCTAGCTACAACGA ACAGGAAA
19763





3922
AGGACGAA G UAUGUCAC
9035
CTCACATA GGCTAGCTACAACGA TTCCTCCT
19764





3924
GAGCAAGU A UGUGACCC
2076
CGCTCACA GGCTAGCTACAACGA ACTTCCTC
19765





3926
GCAAGUAU G UGACCCCA
9036
TGCGCTCA GGCTAGCTACAACGA ATACTTCC
19766





3929
AGUAUCUG A CCCCAAAU
9037
ATTTGCCG GGCTAGCTACAACGA CACATACT
19767





3936
GACCCCAA A UUCCAUUA
9038
TAATGCAA GGCTAGCTACAACGA TTGCCGTC
19768





3941
CAAAUUCC A UUAUGACA
6832
TGTCATAA GGCTAGCTACAACGA CGAATTTG
19769





3944
AUUCCAUU A UGACAACA
2080
TCTTGTCA GGCTAGCTACAACGA AATCCAAT
19770





3947
CCAUUAUG A CAACACAG
9039
CTGTGTTG GGCTAGCTACAACGA CATAATGG
19771





3950
UUAUGACA A CACAGCAG
9040
CTGCTGTG GGCTAGCTACAACGA TGTCATAA
19772





3952
AUGACAAC A CAGCAGGA
6834
TCCTGCTG GGCTAGCTACAACGA GTTGTCAT
19773





3955
ACAACACA G CAGGAAUC
9041
GATTCCTG GGCTAGCTACAACGA TGTGTTGT
19774





3961
CAGCAGGA A UCAGUCAG
9042
CTGACTGA GGCTAGCTACAACGA TCCTGCTG
19775





3965
AGGAAUCA G UCAGUAUC
9043
GATACTGA GGCTAGCTACAACGA TGATTCCT
19776





3969
AUCAGUCA G UAUCUGCA
9044
TGCAGATA GGCTAGCTACAACGA TGACTGAT
19777





3971
CAGUCAGU A UCUGCAGA
2083
TCTGCAGA GGCTAGCTACAACGA ACTGACTG
19778





3975
CAGUAUCU G CAGAACAG
9045
CTGTTCTG GGCTAGCTACAACGA AGATACTG
19779





3980
UCUGCAGA A CAGUAAGC
9046
GCTTACTG GGCTAGCTACAACGA TCTGCAGA
19780





3983
GCAGAACA G UAAGCGAA
9047
TTCGCTTA GGCTAGCTACAACGA TGTTCTGC
19781





3987
AACAGUAA G CGAAAGAG
9048
CTCTTTCG GGCTAGCTACAACGA TTACTGTT
19782





3995
GCGAAAGA G CCGGCCUG
9049
CAGGCCGG GGCTAGCTACAACGA TCTTTCGC
19783





3999
AAGAGCCG G CCUGUGAG
9050
CTCACAGG GGCTAGCTACAACGA CGGCTCTT
19784





4003
GCCGGCCU G UGAGUGUA
9051
TACACTCA GGCTAGCTACAACGA AGGCCGGC
19785





4007
GCCUGUGA G UGUAAAAA
9052
TTTTTACA GGCTAGCTACAACGA TCACAGGC
19786





4009
CUGUGAGU G UAAAAACA
9053
TGTTTTTA GGCTAGCTACAACGA ACTCACAG
19787





4015
GUGUAAAA A CAUUUGAA
9054
TTCAAATG GGCTAGCTACAACGA TTTTACAC
19788





4017
GUAAAAAC A UUUGAAGA
6845
TCTTCAAA GGCTAGCTACAACGA GTTTTTAC
19789





4025
AUUUGAAG A UAUCCCGU
9055
ACGGGATA GGCTAGCTACAACGA CTTCAAAT
19790





4027
UUGAAGAU A UCCCGUUA
2089
TAACGGGA GGCTAGCTACAACGA ATCTTCAA
19791





4032
GAUAUCCC G UUAGAAGA
9056
TCTTCTAA GGCTAGCTACAACGA GGGATATC
19792





4041
UUAGAAGA A CCAGAAGU
9057
ACTTCTGG GGCTAGCTACAACGA TCTTCTAA
19793





4048
AACCAGAA G UAAAAGUA
9058
TACTTTTA GGCTAGCTACAACGA TTCTGGTT
19794





4054
AAGUAAAA G UAAUCCCA
9059
TGGGATTA GGCTAGCTACAACGA TTTTACTT
19795





4057
UAAAAGUA A UCCCAGAU
9060
ATCTGGGA GGCTAGCTACAACGA TACTTTTA
19796





4064
AAUCCCAG A UGACAACC
9061
GGTTGTCA GGCTAGCTACAACGA CTGGGATT
19797





4067
CCCAGAUG A CAACCAGA
9062
ACTGGTTG GGCTAGCTACAACGA CATCTGGG
19798





4070
AGAUGACA A CCAGACGG
9063
CCGTCTGG GGCTAGCTACAACGA TGTCATCT
19799





4075
ACAACCAG A CGGACAGU
9064
ACTGTCCG GGCTAGCTACAACGA CTGGTTGT
19800





4079
CCAGACGG A CAGUGGUA
9065
TACCACTG GGCTAGCTACAACGA CCGTCTGG
19801





4082
GACGGACA G UGGUAUGG
9066
CCATACCA GGCTAGCTACAACGA TGTCCGTC
19802





4085
GGACAGUG G UAUGGUUC
9067
GAACCATA GGCTAGCTACAACGA CACTGTCC
19803





4087
ACAGUGGU A UGGUUCUU
2096
AAGAACCA GGCTAGCTACAACGA ACCACTGT
19804





4090
GUGGUAUG G UUCUUGCC
9068
GGCAAGAA GGCTAGCTACAACGA CATACCAC
19805





4096
UGGUUCUU G CCUCAGAA
9069
TTCTGAGG GGCTAGCTACAACGA AAGAACCA
19806





4107
UCAGAAGA G CUGAAAAC
9070
GTTTTCAG GGCTAGCTACAACGA TCTTCTGA
19807





4114
AGCUGAAA A CUUUGGAA
9071
TTCCAAAG GGCTAGCTACAACGA TTTCAGCT
19808





4124
UUUGGAAG A CAGAACCA
9072
TGGTTCTG GGCTAGCTACAACGA CTTCCAAA
19809





4129
AAGACAGA A CCAAAUUA
9073
TAATTTGG GGCTAGCTACAACGA TCTGTCTT
19810





4134
AGAACCAA A UUAUCUCC
9074
GGAGATAA GGCTAGCTACAACGA TTGGTTCT
19811





4137
ACCAAAUU A UCUCCAUC
2104
GATGGAGA GGCTAGCTACAACGA AATTTGGT
19812





4143
UUAUCUCC A UCUUUUGG
6868
CCAAAAGA GGCTAGCTACAACGA GGAGATAA
19813





4151
AUCUUUUG G UGGAAUGG
9075
CCATTCCA GGCTAGCTACAACGA CAAAAGAT
19814





4156
UUGGUGGA A UGGUGCCC
9076
GGGCACCA GGCTAGCTACAACGA TCCACCAA
19815





4159
GUGGAAUG G UGCCCAGC
9077
GCTGGGCA GGCTAGCTACAACGA CATTCCAC
19816





4161
GGAAUGGU G CCCAGCAA
9078
TTGCTGGG GGCTAGCTACAACGA ACCATTCC
19817





4166
GGUGCCCA G CAAAAGCA
9079
TGCTTTTG GGCTAGCTACAACGA TGGGCACC
19818





4172
CAGCAAAA G CAGGGAGU
9080
ACTCCCTG GGCTAGCTACAACGA TTTTGCTG
19819





4179
AGCAGGGA G UCUGUGGC
9081
GCCACAGA GGCTAGCTACAACGA TCCCTGCT
19820





4183
GGGAGUCU G UGGCAUCU
9082
AGATGCCA GGCTAGCTACAACGA AGACTCCC
19821





4186
AGUCUGUG G CAUCUGAA
9083
TTCAGATG GGCTAGCTACAACGA CACAGACT
19822





4188
UCUGUGGC A UCUGAAGG
6876
CCTTCAGA GGCTAGCTACAACGA GCCACAGA
19823





4196
AUCUGAAG G CUCAAACC
9084
GGTTTGAG GGCTAGCTACAACGA CTTCAGAT
19824





4202
AGGCUCAA A CCAGACAA
9085
TTGTCTGG GGCTAGCTACAACGA TTGAGCCT
19825





4207
CAAACCAG A CAAGCGGC
9086
GCCGCTTG GGCTAGCTACAACGA CTGGTTTG
19826





4211
CCAGACAA G CGGCUACC
9087
GGTAGCCG GGCTAGCTACAACGA TTGTCTGG
19827





4214
GACAAGCG G CUACCAGU
9088
ACTGGTAG GGCTAGCTACAACGA CGCTTGTC
19828





4217
AAGCGGCU A CCAGUCCG
2114
CGGACTGG GGCTAGCTACAACGA AGCCGCTT
19829





4221
GGCUACCA G UCCGGAUA
9089
TATCCGGA GGCTAGCTACAACGA TGGTAGCC
19830





4227
CAGUCCGG A UAUCACUC
9090
GAGTGATA GGCTAGCTACAACGA CCGGACTG
19831





4229
GUCCGGAU A UCACUCCG
2116
CGGAGTGA GGCTAGCTACAACGA ATCCGGAC
19832





4232
CGGAUAUC A CUCCGAUG
6887
CATCGGAG GGCTAGCTACAACGA GATATCCG
19833





4238
UCACUCCG A UGACACAG
9091
CTGTGTCA GGCTAGCTACAACGA CGGAGTGA
19834





4241
CUCCGAUG A CACAGACA
9092
TGTCTGTG GGCTAGCTACAACGA CATCGGAG
19835





4243
CCGAUGAC A CAGACACC
6890
GGTGTCTG GGCTAGCTACAACGA GTCATCGG
19836





4247
UGACACAG A CACCACCG
9093
CGGTGGTG GGCTAGCTACAACGA CTGTGTCA
19837





4249
ACACAGAC A CCACCGUG
6892
CACGGTGG GGCTAGCTACAACGA GTCTGTGT
19838





4252
CAGACACC A CCGUGUAC
6894
GTACACGG GGCTAGCTACAACGA GGTGTCTG
19839





4255
ACACCACC G UGUACUCC
9094
GGAGTACA GGCTAGCTACAACGA GGTGGTGT
19840





4257
ACCACCGU G UACUCCAG
9095
CTGGAGTA GGCTAGCTACAACGA ACGGTGGT
19841





4259
CACCGUGU A CUCCAGUG
2119
CACTGGAG GGCTAGCTACAACGA ACACGGTG
19842





4265
GUACUCCA G UGAGGAAG
9096
CTTCCTCA GGCTAGCTACAACGA TGGAGTAC
19843





4273
GUGAGGAA G CAGAACUU
9097
AAGTTCTG GGCTAGCTACAACGA TTCCTCAC
19844





4278
GAAGCAGA A CUUUUAAA
9098
TTTAAAAG GGCTAGCTACAACGA TCTGCTTC
19845





4287
CUUUUAAA G CUGAUAGA
9099
TCTATCAG GGCTAGCTACAACGA TTTAAAAG
19846





4291
UAAAGCUG A UAGAGAUU
9100
AATCTCTA GGCTAGCTACAACGA CAGCTTTA
19847





4297
UGAUAGAG A UUGGAGUG
9101
CACTCCAA GGCTAGCTACAACGA CTCTATCA
19848





4303
AGAUUGGA G UGCAAACC
9102
GGTTTGCA GGCTAGCTACAACGA TCCAATCT
19849





4305
AUUGGAGU G CAAACCGG
9103
CCGGTTTG GGCTAGCTACAACGA ACTCCAAT
19850





4309
GAGUGCAA A CCGGUAGC
9104
GCTACCGG GGCTAGCTACAACGA TTGCACTC
19851





4313
GCAAACCG G UAGCACAG
9105
CTGTGCTA GGCTAGCTACAACGA CGGTTTGC
19852





4316
AACCGGUA G CACAGCCC
9106
GGGCTGTG GGCTAGCTACAACGA TACCGGTT
19853





4318
CCGGUAGC A CAGCCCAG
6904
CTGGGCTG GGCTAGCTACAACGA GCTACCGG
19854





4321
GUAGCACA G CCCAGAUU
9107
AATCTGGG GGCTAGCTACAACGA TGTGCTAC
19855





4327
CAGCCCAG A UUCUCCAG
9108
CTGGAGAA GGCTAGCTACAACGA CTGGGCTG
19856





4335
AUUCUCCA G CCUGACUC
9109
GAGTCAGG GGCTAGCTACAACGA TGGAGAAT
19857





4340
CCAGCCUG A CUCGGGGA
9110
TCCCCGAG GGCTAGCTACAACGA CAGCCTGG
19858





4348
ACUCGGGG A CCACACUG
9111
CAGTGTGG GGCTAGCTACAACGA CCCCGAGT
19859





4351
CGGGGACC A CACUGAGC
6916
GCTCAGTG GGCTAGCTACAACGA GGTCCCCG
19860





4353
GGGACCAC A CUGAGCUC
6917
GAGCTCAG GGCTAGCTACAACGA GTGGTCCC
19861





4358
CACACUGA G CUCUCCUC
9112
GAGGAGAG GGCTAGCTACAACGA TCAGTGTG
19862





4369
CUCCUCCU G UUUAAAAG
9113
CTTTTAAA GGCTAGCTACAACGA AGGAGGAG
19863





4381
AAAAGGAA G CAUCCACA
9114
TGTGGATG GGCTAGCTACAACGA TTCCTTTT
19864





4383
AAGGAAGC A UCCACACC
6925
GGTGTGGA GGCTAGCTACAACGA GCTTCCTT
19865





4387
AAGCAUCC A CACCCCAA
6927
TTGGGGTG GGCTAGCTACAACGA GGATCCTT
19866





4389
GCAUCCAC A CCCCAACU
6928
AGTTGGCG GGCTAGCTACAACGA GTGGATGC
19867





4395
ACACCCCA A CUCCCGGA
9115
TCCGGGAG GGCTAGCTACAACGA TGGGGTGT
19868





4403
ACUCCCGG A CAUCACAU
9116
ATGTGATG GGCTAGCTACAACGA CCGGGAGT
19869





4405
UCCCGGAC A UCACAUGA
6936
TCATGTGA GGCTAGCTACAACGA GTCCGGGA
19870





4408
CGGACAUC A CAUGAGAG
6937
CTCTCATG GGCTAGCTACAACGA GATGTCCG
19871





4410
GACAUCAC A UGAGAGGU
6938
ACCTCTCA GGCTAGCTACAACGA GTGATGTC
19872





4417
CAUGAGAG G UCUGCUCA
9117
TGAGCAGA GGCTAGCTACAACGA CTCTCATG
19873





4421
AGAGGUCU G CUCAGAUU
9118
AATCTGAG GGCTAGCTACAACGA AGACCTCT
19874





4427
CUGCUCAG A UUUUGAAG
9119
CTTCAAAA GGCTAGCTACAACGA CTGAGCAG
19875





4435
AUUUUGAA G UGUUGUUC
9120
GAACAACA GGCTAGCTACAACGA TTCAAAAT
19876





4437
UUUGAAGU G UUGUUCUU
9121
AAGAACAA GGCTAGCTACAACGA ACTTCAAA
19877





4440
GAAGUGUU G UUCUUUCC
9122
GGAAAGAA GGCTAGCTACAACGA AACACTTC
19878





4449
UUCUUUCC A CCAGCAGG
6944
CCTGCTGG GGCTAGCTACAACGA GGAAAGAA
19879





4453
UUCCACCA G CAGGAAGU
9123
ACTTCCTG GGCTAGCTACAACGA TGGTGGAA
19880





4460
AGCAGGAA G UAGCCGCA
9124
TGCGGCTA GGCTAGCTACAACGA TTCCTGCT
19881





4463
AGGAAGUA G CCGCAUUU
9125
AAATGCGG GGCTAGCTACAACGA TACTTCCT
19882





4466
AAGUAGCC G CAUUUGAU
9126
ATCAAATG GGCTAGCTACAACGA GGCTACTT
19883





4468
GUAGCCGC A UUUGAUUU
6949
AAATCAAA GGCTAGCTACAACGA GCGGCTAC
19884





4473
CGCAUUUG A UUUUCAUU
9127
AATGAAAA GGCTAGCTACAACGA CAAATGCG
19885





4479
UGAUUUUC A UUUCGACA
6950
TGTCGAAA GGCTAGCTACAACGA GAAAATCA
19886





4485
UCAUUUCG A CAACAGAA
9128
TTCTGTTG GGCTAGCTACAACGA CGAAATGA
19887





4488
UUUCGACA A CAGAAAAA
9129
TTTTTCTG GGCTAGCTACAACGA TGTCGAAA
19888





4499
GAAAAAGG A CCUCGGAC
9130
GTCCGAGG GGCTAGCTACAACGA CCTTTTTC
19889





4506
GACCUCGG A CUGCAGGG
9131
CCCTGCAG GGCTAGCTACAACGA CCGAGGTC
19890





4509
CUCGGACU G CAGGGAGC
9132
GCTCCCTG GGCTAGCTACAACGA AGTCCGAG
19891





4516
UGCAGGGA G CCAGUCUU
9133
AAGACTGG GGCTAGCTACAACGA TCCCTGCA
19892





4520
GGGAGCCA G UCUUCUAG
9134
CTAGAAGA GGCTAGCTACAACGA TGGCTCCC
19893





4529
UCUUCUAG G CAUAUCCU
9135
AGGATATG GGCTAGCTACAACGA CTAGAAGA
19894





4531
UUCUAGGC A UAUCCUGG
9136
CCAGGATA GGCTAGCTACAACGA GCCTAGAA
19895





4533
CUAGGCAU A UCCUGGAA
9137
TTCCAGGA GGCTAGCTACAACGA ATGCCTAG
19896





4545
UGGAAGAG G CUUGUGAC
9138
GTCACAAG GGCTAGCTACAACGA CTCTTCCA
19897





4549
AGAGGCUU G UGACCCAA
9139
TTGGGTCA GGCTAGCTACAACGA AAGCCTCT
19898





4552
GGCUUGUG A CCCAAGAA
9140
TTCTTGGG GGCTAGCTACAACGA CACAAGCC
19899





4560
ACCCAAGA A UGUGUCUG
9141
CAGACACA GGCTAGCTACAACGA TCTTGGGT
19900





4562
CCAAGAAU G UGUCUGUG
9142
CACAGACA GGCTAGCTACAACGA ATTCTTGG
19901





4564
AAGAAUGU G UCUGUGUC
9143
GACACAGA GGCTAGCTACAACGA ACATTCTT
19902





4568
AUGUGUCU G UGUCUUCU
9144
AGAAGACA GGCTAGCTACAACGA AGACACAT
19903





4570
GUGUCUGU G UCUUCUCC
9145
GGAGAAGA GGCTAGCTACAACGA ACAGACAC
19904





4581
UUCUCCCA G UGUUGACC
9146
GGTCAACA GGCTAGCTACAACGA TGGGAGAA
19905





4583
CUCCCAGU G UUGACCUG
9147
CAGGTCAA GGCTAGCTACAACGA ACTGGGAG
19906





4587
CAGUGUUG A CCUGAUCC
9148
GGATCAGG GGCTAGCTACAACGA CAACACTG
19907





4592
UUGACCUG A UCCUCUUU
9149
AAAGAGGA GGCTAGCTACAACGA CAGGTCAA
19908





4605
CUUUUUUC A UUCAUUUA
9150
TAAATGAA GGCTAGCTACAACGA GAAAAAAG
19909





4609
UUUCAUUC A UUUAAAAA
9151
TTTTTAAA GGCTAGCTACAACGA GAATGAAA
19910





4618
UUUAAAAA G CAUUAUCA
9152
TGATAATG GGCTAGCTACAACGA TTTTTAAA
19911





4620
UAAAAAGC A UUAUCAUG
9153
CATGATAA GGCTAGCTACAACGA GCTTTTTA
19912





4623
AAAGCAUU A UCAUGCCC
9154
GGGCATGA GGCTAGCTACAACGA AATGCTTT
19913





4626
GCAUUAUC A UGCCCCUG
9155
CAGGGGCA GGCTAGCTACAACGA GATAATGC
19914





4628
AUUAUCAU G CCCCUGCU
9156
AGCAGGGG GGCTAGCTACAACGA ATGATAAT
19915





4634
AUGCCCCU G CUGCGGGU
9157
ACCCGCAG GGCTAGCTACAACGA AGGGGCAT
19916





4637
CCCCUGCU G CGGGUCUC
9158
GAGACCCG GGCTAGCTACAACGA AGCAGGGG
19917





4641
UGCUGCGG G UCUCACCA
9159
TGGTGAGA GGCTAGCTACAACGA CCGCAGCA
19918





4646
CGGGUCUC A CCAUGGGU
9160
ACCCATGG GGCTAGCTACAACGA GAGACCCG
19919





4649
GUCUCACC A UGGGUUUA
9161
TAAACCCA GGCTAGCTACAACGA GGTGAGAC
19920





4653
CACCAUGG G UUUAGAAC
9162
GTTCTAAA GGCTAGCTACAACGA CCATGGTG
19921





4660
GGUUUAGA A CAAAGAGC
9163
GCTCTTTG GGCTAGCTACAACGA TCTAAACC
19922





4667
AACAAAGA G CUUCAAGC
9164
GCTTGAAG GGCTAGCTACAACGA TCTTTGTT
19923





4674
AGCUUCAA G CAAUGGCC
9165
GGCCATTG GGCTAGCTACAACGA TTGAAGCT
19924





4677
UUCAACCA A UGGCCCCA
9166
TGGGGCCA GGCTAGCTACAACGA TGCTTGAA
19925





4680
AAGCAAUG G CCCCAUCC
9167
GGATGGGG GGCTAGCTACAACGA CATTGCTT
19926





4685
AUGGCCCC A UCCUCAAA
9168
TTTGAGGA GGCTAGCTACAACGA GGGGCCAT
19927





4697
UCAAAGAA G UAGCAGUA
9169
TACTGCTA GGCTAGCTACAACGA TTCTTTGA
19928





4700
AAGAAGUA G CAGUACCU
9170
AGGTACTG GGCTAGCTACAACGA TACTTCTT
19929





4703
AAGUAGCA G UACCUGGG
9171
CCCAGGTA GGCTAGCTACAACGA TGCTACTT
19930





4705
GUAGCAGU A CCUGGGGA
9172
TCCCCAGG GGCTAGCTACAACGA ACTGCTAC
19931





4714
CCUGGGGA G CUGACACU
9173
AGTGTCAG GGCTAGCTACAACGA TCCCCAGG
19932





4718
GGGAGCUG A CACUUCUG
9174
CAGAAGTG GGCTAGCTACAACGA CAGCTCCC
19933





4720
GAGCUGAC A CUUCUGUA
9175
TACAGAAG GGCTAGCTACAACGA GTCACCTC
19934





4726
ACACUUCU G UAAAACUA
9176
TAGTTTTA GGCTAGCTACAACGA AGAAGTGT
19935





4731
UCUGUAAA A CUAGAAGA
9177
TCTTCTAG GGCTAGCTACAACGA TTTACAGA
19936





4739
ACUAGAAG A UAAACCAG
9178
CTGGTTTA GGCTAGCTACAACGA CTTCTAGT
19937





4743
GAAGAUAA A CCAGGCAA
9179
TTGCCTGG GGCTAGCTACAACGA TTATCTTC
19938





4748
UAAACCAG G CAACGUAA
9180
TTACGTTG GGCTAGCTACAACGA CTGGTTTA
19939





4751
ACCAGGCA A CGUAAGUG
9181
CACTTACG GGCTAGCTACAACGA TGCCTGGT
19940





4753
CAGGCAAC G UAAGUGUU
9182
AACACTTA GGCTAGCTACAACGA GTTGCCTG
19941





4757
CAACGUAA G UGUUCGAG
9183
CTCGAACA GGCTAGCTACAACGA TTACGTTG
19942





4759
ACGUAAGU G UUCGAGGU
9184
ACCTCGAA GGCTAGCTACAACGA ACTTACGT
19943





4766
UGUUCGAG G UGUUGAAG
9185
CTTCAACA GGCTAGCTACAACGA CTCGAACA
19944





4768
UUCGAGGU G UUGAAGAU
9186
ATCTTCAA GGCTAGCTACAACGA ACCTCGAA
19945





4775
UGUUGAAG A UGGGAAGG
9187
CCTTCCCA GGCTAGCTACAACGA CTTCAACA
19946





4784
UGGGAAGG A UUUGCAGG
9188
CCTGCAAA GGCTAGCTACAACGA CCTTCCCA
19947





4788
AAGGAUUU G CAGGGCUC
9189
CAGCCCTG GGCTAGCTACAACGA AAATCCTT
19948





4793
UUUGCAGG G CUGAGUCU
9190
AGACTCAG GGCTAGCTACAACGA CCTGCAAA
19949





4798
AGGGCUGA G UCUAUCCA
9191
TGGATAGA GGCTAGCTACAACGA TCAGCCCT
19950





4802
CUGACUCU A UCCAAGAG
9192
CTCTTGGA GGCTAGCTACAACGA AGACTCAG
19951





4811
UCCAAGAG G CUUUGUUU
9193
AAACAAAG GGCTAGCTACAACGA CTCTTGGA
19952





4816
GAGGCUUU G UUUAGGAC
9194
GTCCTAAA GGCTAGCTACAACGA AAAGCCTC
19953





4823
UGUUUAGG A CGUGGGUC
9195
GACCCACG GGCTAGCTACAACGA CCTAAACA
19954





4825
UUUAGGAC G UGGGUCCC
9196
GGGACCCA GGCTAGCTACAACGA GTCCTAAA
19955





4829
CGACGUGG G UCCCAAGC
9197
GCTTGGGA GGCTAGCTACAACGA CCACGTCC
19956





4836
GGUCCCAA G CCAAGCCU
9198
AGGCTTGG GGCTAGCTACAACGA TTGGGACC
19957





4841
CAACCCAA G CCUUAAGU
9199
ACTTAAGG GGCTAGCTACAACGA TTGGCTTG
19958





4848
AGCCUUAA G UGUGGAAU
9200
ATTCCACA GGCTAGCTACAACGA TTAAGGCT
19959





4850
CCUUAAGU G UGGAAUUC
9201
GAATTCCA GGCTAGCTACAACGA ACTTAAGG
19960





4855
AGUGUCCA A UUCGCAUU
9202
AATCCGAA GGCTAGCTACAACGA TCCACACT
19961





4861
GAAUUCGG A UUGAUAGA
9203
TCTATCAA GCCTAGCTACAACGA CCGAATTC
19962





4865
UCGGAUUG A UAGAAAGC
9204
CCTTTCTA GGCTAGCTACAACGA CAATCCGA
19963





4877
AAAGGAAG A CUAACGUU
9205
AACGTTAG GGCTAGCTACAACGA CTTCCTTT
19964





4881
GAAGACUA A CGUUACCU
9206
AGGTAACG GGCTAGCTACAACGA TAGTCTTC
19965





4883
AGACUAAC G UUACCUUG
9207
CAAGGTAA GCCTAGCTACAACGA GTTAGTCT
19966





4886
CUAACGUU A CCUUGCUU
9208
AAGCAAGG GGCTAGCTACAACGA AACGTTAG
19967





4891
GUUACCUU G CUUUGGAG
9209
CTCCAAAG GGCTAGCTACAACGA AAGGTAAC
19968





4901
UUUGGAGA G UACUGGAG
9210
CTCCAGTA GGCTAGCTACAACGA TCTCCAAA
19969





4903
UGGAGAGU A CUGGAGCC
9211
GGCTCCAG GGCTAGCTACAACGA ACTCTCCA
19970





4909
GUACUGGA G CCUGCAAA
9212
TTTGCAGG GGCTAGCTACAACGA TCCAGTAC
19971





4913
UCGAGCCU G CAAAUGCA
9213
TGCATTTG GGCTAGCTACAACGA AGGCTCCA
19972





4917
GCCUGCAA A UGCAUUGU
9214
ACAATGCA GGCTAGCTACAACGA TTGCAGGC
19973





4919
CUGCAAAU G CAUUGUGU
9215
ACACAATG GGCTAGCTACAACGA ATTTGCAG
19974





4921
GCAAAUGC A UUGUGUUU
9216
AAACACAA GGCTAGCTACAACGA GCATTTGC
19975





4924
AAUGCAUU G UCUUUGCU
9217
AGCAAACA GGCTAGCTACAACGA AATGCATT
19976





4926
UGCAUUGU G UUUGCUCU
9218
AGAGCAAA GGCTAGCTACAACGA ACAATGCA
19977





4930
UUGUGUUU G CUCUGGUG
9219
CACCAGAG GGCTAGCTACAACGA AAACACAA
19978





4936
UUGCUCUG G UGGAGGUG
9220
CACCTCCA GGCTAGCTACAACGA CAGAGCAA
19979





4942
UGGUGGAG G UGGGCAUG
9221
CATGCCCA GGCTAGCTACAACGA CTCCACCA
19980





4946
GGAGGUGG G CAUGGGGU
9222
ACCCCATG GGCTAGCTACAACGA CCACCTCC
19981





4948
AGGUGGGC A UGGGGUCU
9223
AGACCCCA GGCTAGCTACAACGA GCCCACCT
19982





4953
GGCAUGGG G UCUGUUCU
9224
AGAACAGA GGCTAGCTACAACGA CCCATGCC
19983





4957
UGGGGUCU G UUCUGAAA
9225
TTTCAGAA GGCTAGCTACAACGA AGACCCCA
19984





4965
GUUCUGAA A UGUAAAGG
9226
CCTTTACA GGCTAGCTACAACGA TTCAGAAC
19985





4967
UCUGAAAU G UAAAGGGU
9227
ACCCTTTA GGCTAGCTACAACGA ATTTCAGA
19986





4974
UGUAAAGG G UUCAGACG
9228
CGTCTGAA GGCTAGCTACAACGA CCTTTACA
19987





4980
GCGUUCAG A CGGGGUUU
9229
AAACCCCG GGCTAGCTACAACGA CTGAACCC
19988





4985
CAGACGGG G UUUCUGGU
9230
ACCAGAAA GGCTAGCTACAACGA CCCGTCTG
19989





4992
GGUUUCUG G UUUUAGAA
9231
TTCTAAAA GGCTAGCTACAACGA CAGAAACC
19990





5002
UUUAGAAG G UUGCGUGU
9232
ACACGCAA GGCTAGCTACAACGA CTTCTAAA
19991





5005
AGAAGGUU G CGUGUUCU
9233
ACAACACG GGCTAGCTACAACGA AACCTTCT
19992





5007
AAGGUUGC G UGUUCUUC
9234
GAAGAACA GGCTAGCTACAACGA GCAACCTT
19993





5009
GGUUGCGU G UUCUUCGA
9235
TCGAAGAA GGCTAGCTACAACGA ACGCAACC
19994





5018
UUCUUCGA G UUGGGCUA
9236
TACCCCAA GCCTAGCTACAACGA TCGAAGAA
19995





5023
CGAGUUGG G CUAAAGUA
9237
TACTTTAG GGCTAGCTACAACGA CCAACTCG
19996





5029
GGGCUAAA G UAGAGUUC
9238
GAACTCTA GGCTAGCTACAACGA TTTAGCCC
19997





5034
AAAGUACA G UUCGUUGU
9239
ACAACGAA GGCTAGCTACAACGA TCTACTTT
19998





5038
UAGAGUUC G UUGUGCUG
9240
CAGCACAA GGCTAGCTACAACGA GAACTCTA
19999





5041
AGUUCGUU G UGCUGUUU
9241
AAACAGCA GGCTAGCTACAACGA AACGAACT
20000





5043
UUCGUUGU G CUGUUUCU
9242
AGAAACAG GGCTAGCTACAACGA ACAACGAA
20001





5046
GUUGUGCU G UUUCUCAC
9243
GTCAGAAA GGCTAGCTACAACGA AGCACAAC
20002





5053
UGUUUCUG A CUCCUAAU
9244
ATTAGGAG GGCTAGCTACAACGA CAGAAACA
20003





5060
GACUCCUA A UGAGAGUU
9245
AACTCTCA GGCTAGCTACAACGA TAGGAGTC
20004





5066
UAAUGAGA G UUCCUUCC
9246
GGAAGGAA GGCTAGCTACAACGA TCTCATTA
20005





5077
CCUUCCAG A CCCUUACC
9247
GCTAACCG GGCTAGCTACAACGA CTGGAAGG
20006





5080
UCCAGACC G UUACCUGU
9248
ACAGCTAA GGCTAGCTACAACGA GCTCTGGA
20007





5084
GACCGUUA G CUGUCUCC
9249
GGAGACAG GGCTAGCTACAACGA TAACGGTC
20008





5087
CCUUACCU G UCUCCUUG
9250
CAAGGACA GGCTAGCTACAACGA AGCTAACG
20009





5095
GUCUCCUU G CCAAGCCC
9251
GCGCTTGG GGCTAGCTACAACGA AAGGAGAC
20010





5100
CUUGCCAA G CCCCACGA
9252
TCCTGGCG GGCTAGCTACAACGA TTCGCAAG
20011





5114
GGAAGAAA A UGAUCCAG
9253
CTGCATCA GGCTAGCTACAACGA TTTCTTCC
20012





5117
AGAAAAUG A UCCACCUC
9254
GACCTGCA GGCTAGCTACAACGA CATTTTCT
20013





5119
AAAAUGAU G CACCUCUG
9255
CAGACCTG GGCTAGCTACAACGA ATCATTTT
20014





5122
AUGAUCCA G CUCUGGCU
9256
ACCCAGAG GGCTAGCTACAACGA TGCATCAT
20015





5128
CAGCUCUG G CUCCUUGU
9257
ACAAGGAG GGCTAGCTACAACGA CAGAGCTG
20016





5135
GGCUCCUU G UCUCCCAG
9258
CTGGGAGA GGCTAGCTACAACGA AAGGAGCC
20017





5144
UCUCCCAG G CUGAUCCU
9259
AGGATCAG GGCTAGCTACAACGA CTGGGAGA
20018





5148
CCAGGCUG A UCCUUUAU
9260
ATAAAGGA GGCTAGCTACAACGA CAGCCTGG
20019





5155
GAUCCUUU A UUCAGAAU
9261
ATTCTGAA GGCTAGCTACAACGA AAAGGATC
20020





5162
UAUUCAGA A UACCACAA
9262
TTGTGGTA GGCTAGCTACAACGA TCTGAATA
20021





5164
UUCAGAAU A CCACAAAG
9263
CTTTGTGG GGCTAGCTACAACGA ATTCTGAA
20022





5167
AGAAUACC A CAAAGAAA
9264
TTTCTTTG GGCTAGCTACAACGA GGTATTCT
20023





5178
AAGAAAGG A CAUUCAGC
9265
GCTGAATG GGCTAGCTACAACGA CCTTTCTT
20024





5180
GAAAGGAC A UUCAGCUC
9266
GAGCTGAA GGCTAGCTACAACGA GTCCTTTC
20025





5185
GACAUUCA G CUCAAGGC
9267
GCCTTGAG GGCTAGCTACAACGA TGAATGTC
20026





5192
AGCUCAAG G CUCCCUGC
9268
GCAGGGAG GGCTAGCTACAACGA CTTGAGCT
20027





5199
GGCUCCCU G CCGUGUUG
9269
CAACACGG GGCTAGCTACAACGA AGGGAGCC
20028





5202
UCCCUGCC G UGUUGAAG
9270
CTTCAACA GGCTAGCTACAACGA GGCAGGGA
20029





5204
CCUGCCGU G UUGAAGAG
9271
CTCTTCAA GGCTAGCTACAACGA ACGGCAGG
20030





5212
GUUGAAGA G UUCUGACU
9272
AGTCAGAA GGCTAGCTACAACGA TCTTCAAC
20031





5218
GAGUUCUG A CUGCACAA
9273
TTGTGCAG GGCTAGCTACAACGA CAGAACTC
20032





5221
UUCUGACU G CACAAACC
9274
GGTTTGTG GGCTAGCTACAACGA AGTCAGAA
20033





5223
CUGACUGC A CAAACCAG
9275
CTGGTTTG GGCTAGCTACAACGA GCAGTCAG
20034





5227
CUGCACAA A CCAGCUUC
9276
GAAGCTGG GGCTAGCTACAACGA TTGTGCAG
20035





5231
ACAAACCA G CUUCUGGU
9277
ACCAGAAG GGCTAGCTACAACGA TGGTTTGT
20036





5238
AGCUUCUG G UUUCUUCU
9278
AGAAGAAA GGCTAGCTACAACGA CAGAAGCT
20037





5250
CUUCUGGA A UGAAUACC
9279
GCTATTCA GGCTAGCTACAACGA TCCAGAAG
20038





5254
UGGAAUGA A UACCCUCA
9280
TGAGGGTA GGCTAGCTACAACGA TCATTCCA
20039





5256
GAAUGAAU A CCCUCAUA
9281
TATGAGGG GGCTAGCTACAACGA ATTCATTC
20040





5262
AUACCCUC A UAUCUGUC
9282
GACAGATA GGCTAGCTACAACGA GAGGGTAT
20041





5264
ACCCUCAU A UCUGUCCU
9283
AGGACAGA GGCTAGCTACAACGA ATGAGGGT
20042





5268
UCAUAUCU G UCCUGAUG
9284
CATCAGGA GGCTAGCTACAACGA AGATATGA
20043





5274
CUGUCCUG A UGUGAUAU
9285
ATATCACA GGCTAGCTACAACGA CAGGACAG
20044





5276
GUCCUGAU G UGAUAUGU
9286
ACATATCA GGCTAGCTACAACGA ATCAGGAC
20045





5279
CUGAUGUG A UAUGUCUG
9287
CAGACATA GGCTAGCTACAACGA CACATCAG
20046





5281
GAUGUGAU A UGUCUGAG
9288
CTCAGACA GGCTAGCTACAACGA ATCACATC
20047





5283
UGUGAUAU G UCUGAGAC
9289
GTCTCAGA GGCTAGCTACAACGA ATATCACA
20048





5290
UGUCUGAG A CUGAAUGC
9290
GCATTCAG GGCTAGCTACAACGA CTCAGACA
20049





5295
GAGACUGA A UGCGGGAG
9291
CTCCCGCA GGCTAGCTACAACGA TCAGTCTC
20050





5297
GACUGAAU G CGGGAGGU
9292
ACCTCCCG GGCTAGCTACAACGA ATTCAGTC
20051





5304
UGCGGGAG G UUCAAUGU
9293
ACATTGAA GGCTAGCTACAACGA CTCCCGCA
20052





5309
GAGGUUCA A UGUGAAGC
9294
GCTTCACA GGCTAGCTACAACGA TGAACCTC
20053





5311
GGUUCAAU G UGAAGCUG
9295
CAGCTTCA GGCTAGCTACAACGA ATTGAACC
20054





5316
AAUGUGAA G CUGUGUGU
9296
ACACACAG GGCTAGCTACAACGA TTCACATT
20055





5319
GUGAAGCU G UGUGUGGU
9297
ACCACACA GGCTAGCTACAACGA AGCTTCAC
20056





5321
GAAGCUGU G UGUGGUGU
9298
ACACCACA GGCTAGCTACAACGA ACAGCTTC
20057





5323
AGCUGUGU G UGGUGUCA
9299
TGACACCA GGCTAGCTACAACGA ACACAGCT
20058





5326
UGUGUGUG G UGUCAAAG
9300
CTTTGACA GGCTAGCTACAACGA CACACACA
20059





5328
UGUGUGGU G UCAAAGUU
9301
AACTTTGA GGCTAGCTACAACGA ACCACACA
20060





5334
GUGUCAAA G UUUCAGGA
9302
TCCTGAAA GGCTAGCTACAACGA TTTGACAC
20061





5346
CAGGAAGG A UUUUACCC
9303
GGGTAAAA GGCTAGCTACAACGA CCTTCCTG
20062





5351
AGGAUUUU A CCCUUUUG
9304
CAAAAGGG GGCTAGCTACAACGA AAAATCCT
20063





5359
ACCCUUUU G UUCUUCCC
9305
GGGAAGAA GGCTAGCTACAACGA AAAAGGGT
20064





5371
UUCCCCCU G UCCCCAAC
9306
GTTGGGGA GGCTAGCTACAACGA AGGGGGAA
20065





5378
UGUCCCCA A CCCACUCU
9307
AGAGTGGG GGCTAGCTACAACGA TGGGGACA
20066





5382
CCCAACCC A CUCUCACC
9308
GGTGAGAG GGCTAGCTACAACGA GGGTTGGG
20067





5388
CCACUCUC A CCCCGCAA
9309
TTGCGGGG GGCTAGCTACAACGA GAGAGTGG
20068





5393
CUCACCCC G CAACCCAU
9310
ATGGGTTG GGCTAGCTACAACGA GGGGTGAG
20069





5396
ACCCCGCA A CCCAUCAG
9311
CTGATGGG GGCTAGCTACAACGA TGCGGGGT
20070





5400
CGCAACCC A UCAGUAUU
9312
AATACTGA GGCTAGCTACAACGA GGGTTGCG
20071





5404
ACCCAUCA G UAUUUUAG
9313
CTAAAATA GGCTAGCTACAACGA TGATGGGT
20072





5406
CCAUCAGU A UUUUAGUU
9314
AACTAAAA GGCTAGCTACAACGA ACTGATGG
20073





5412
GUAUUUUA G UUAUUUGG
9315
CCAAATAA GGCTAGCTACAACGA TAAAATAC
20074





5415
UUUUAGUU A UUUGGCCU
9316
AGGCCAAA GGCTAGCTACAACGA AACTAAAA
20075





5420
GUUAUUUG G CCUCUACU
9317
AGTAGAGG GGCTAGCTACAACGA CAAATAAC
20076





5426
UGGCCUCU A CUCCAGUA
9318
TACTGGAG GGCTAGCTACAACGA AGAGGCCA
20077





5432
CUACUCCA G UAAACCUG
9319
CAGGTTTA GGCTAGCTACAACGA TGGAGTAG
20078





5436
UCCAGUAA A CCUGAUUG
9320
CAATCAGG GGCTAGCTACAACGA TTACTGGA
20079





5441
UAAACCUG A UUGGGUUU
9321
AAACCCAA GGCTAGCTACAACGA CAGGTTTA
20080





5446
CUGAUUGG G UUUGUUCA
9322
TGAACAAA GGCTAGCTACAACGA CCAATCAG
20081





5450
UUGGGUUU G UUCACUCU
9323
AGAGTGAA GGCTAGCTACAACGA AAACCCAA
20082





5454
GUUUGUUC A CUCUCUGA
9324
TCAGAGAG GGCTAGCTACAACGA GAACAAAC
20083





5463
CUCUCUGA A UGAUUAUU
9325
AATAATCA GGCTAGCTACAACGA TCAGAGAG
20084





5466
UCUGAAUG A UUAUUAGC
9326
GCTAATAA GGCTAGCTACAACGA CATTCAGA
20085





5469
GAAUGAUU A UUAGCCAG
9327
CTGGCTAA GGCTAGCTACAACGA AATCATTC
20086





5473
GAUUAUUA G CCAGACUU
9328
AAGTCTGG GGCTAGCTACAACGA TAATAATC
20087





5478
UUAGCCAG A CUUCAAAA
9329
TTTTGAAG GGCTAGCTACAACGA CTGGCTAA
20088





5486
ACUUCAAA A UUAUUUUA
9330
TAAAATAA GGCTAGCTACAACGA TTTGAAGT
20089





5489
UCAAAAUU A UUUUAUAG
9331
CTATAAAA GGCTAGCTACAACGA AATTTTGA
20090





5494
AUUAUUUU A UAGCCCAA
9332
TTGGGCTA GGCTAGCTACAACGA AAAATAAT
20091





5497
AUUUUAUA G CCCAAAUU
9333
AATTTGGG GGCTAGCTACAACGA TATAAAAT
20092





5503
UAGCCCAA A UUAUAACA
9334
TGTTATAA GGCTAGCTACAACGA TTGGGCTA
20093





5506
CCCAAAUU A UAACAUCU
9335
AGATGTTA GGCTAGCTACAACGA AATTTGGG
20094





5509
AAAUUAUA A CAUCUAUU
9336
AATAGATG GGCTAGCTACAACGA TATAATTT
20095





5511
AUUAUAAC A UCUAUUGU
9337
ACAATAGA GGCTAGCTACAACGA GTTATAAT
20096





5515
UAACAUCU A UUGUAUUA
9338
TAATACAA GGCTAGCTACAACGA AGATGTTA
20097





5518
CAUCUAUU G UAUUAUUU
9339
AAATAATA GGCTAGCTACAACGA AATAGATG
20098





5520
UCUAUUGU A UUAUUUAG
9340
CTAAATAA GGCTAGCTACAACGA ACAATAGA
20099





5523
AUUGUAUU A UUUAGACU
9341
AGTCTAAA GGCTAGCTACAACGA AATACAAT
20100





5529
UUAUUUAG A CUUUUAAC
9342
GTTAAAAG GGCTAGCTACAACGA CTAAATAA
20101





5536
GACUUUUA A CAUAUAGA
9343
TCTATATG GGCTAGCTACAACGA TAAAAGTC
20102





5538
CUUUUAAC A UAUAGAGC
9344
GCTCTATA GGCTAGCTACAACGA GTTAAAAG
20103





5540
UUUAACAU A UAGAGCUA
9345
TAGCTCTA GGCTAGCTACAACGA ATGTTAAA
20104





5545
CAUAUAGA G CUAUUUCU
9346
AGAAATAG GGCTAGCTACAACGA TCTATATG
20105





5548
AUAGAGCU A UUUCUACU
9347
AGTAGAAA GGCTAGCTACAACGA AGCTCTAT
20106





5554
CUAUUUCU A CUGAUUUU
9348
AAAATCAG GGCTAGCTACAACGA AGAAATAG
20107





5558
UUCUACUG A UUUUUGCC
9349
GGCAAAAA GGCTAGCTACAACGA CAGTAGAA
20108





5564
UGAUUTUU G CCCUUGUU
9350
AACAAGGG GGCTAGCTACAACGA AAAAATCA
20109





5570
UUGCCCUU G UUCUGUCC
9351
GGACAGAA GGCTAGCTACAACGA AAGGGCAA
20110





5575
CUUGUUCU G UCCUUUUU
9352
AAAAAGGA GGCTAGCTACAACGA AGAACAAG
20111





5597
AAAAGAAA A UGUGUUUU
9353
AAAACACA GGCTAGCTACAACGA TTTCTTTT
20112





5599
AAGAAAAU G UGUUUUUU
9354
AAAAAACA GGCTAGCTACAACGA ATTTTCTT
20113





5601
GAAAAUGU G UUUUUUGU
9355
ACAAAAAA GGCTAGCTACAACGA ACATTTTC
20114





5608
UGUUUUUU G UUUGGUAC
9356
GTACCAAA GGCTAGCTACAACGA AAAAAACA
20115





5613
UUUGUUUG G UACCAUAG
9357
CTATGGTA GGCTAGCTACAACGA CAAACAAA
20116





5615
UGUUUGGU A CCAUAGUG
9358
CACTATGG GGCTAGCTACAACGA ACCAAACA
20117





5618
UUGGUACC A UAGUGUGA
9359
TCACACTA GGCTAGCTACAACGA GGTACCAA
20118





5621
GUACCAUA G UGUGAAAU
9360
ATTTCACA GGCTAGCTACAACGA TATGGTAC
20119





5623
ACCAUAGU G UGAAAUGC
9361
GCATTTCA GGCTAGCTACAACGA ACTATGGT
20120





5628
AGUGUGAA A UGCUGGGA
9362
TCCCAGCA GGCTAGCTACAACGA TTCACACT
20121





5630
UGUGAAAU G CUGGGAAC
9363
GTTCCCAG GGCTAGCTACAACGA ATTTCACA
20122





5637
UGCUGGGA A CAAUGACU
9364
AGTCATTG GGCTAGCTACAACGA TCCCAGCA
20123





5640
UGGGAACA A UGACUAUA
9365
TATAGTCA GGCTAGCTACAACGA TGTTCCCA
20124





5643
GAACAAUG A CUAUAAGA
9366
TCTTATAG GGCTAGCTACAACGA CATTGTTC
20125





5646
CAAUGACU A UAAGACAU
9367
ATGTCTTA GGCTAGCTACAACGA AGTCATTG
20126





5651
ACUAUAAG A CAUGCUAU
9368
ATAGCATG GGCTAGCTACAACGA CTTATAGT
20127





5653
UAUAAGAC A UGCUAUGG
9369
CCATAGCA GGCTAGCTACAACGA GTCTTATA
20128





5655
UAAGACAU G CUAUGGCA
9370
TGCCATAG GGCTAGCTACAACGA ATGTCTTA
20129





5658
GACAUGCU A UGGCACAU
9371
ATGTGCCA GGCTAGCTACAACGA AGCATGTC
20130





5661
AUGCUAUG G CACAUAUA
9372
TATATGTG GGCTAGCTACAACGA CATAGCAT
20131





5663
GCUAUGGC A CAUAUAUU
9373
AATATATG GGCTAGCTACAACGA GCCATAGC
20132





5665
UAUGGCAC A UAUAUUUA
9374
TAAATATA GGCTAGCTACAACGA GTGCCATA
20133





5667
UGGCACAU A UAUUUAUA
9375
TATAAATA GGCTAGCTACAACGA ATGTGCCA
20134





5669
GCACAUAU A UUUAUAGU
9376
ACTATAAA GGCTAGCTACAACGA ATATGTGC
20135





5673
AUAUAUUU A UAGUCUGU
9377
ACAGACTA GGCTAGCTACAACGA AAATATAT
20136





5676
UAUUUAUA G UCUGUUUA
9378
TAAACAGA GGCTAGCTACAACGA TATAAATA
20137





5680
UAUAGUCU G UUUAUGUA
9379
TACATAAA GGCTAGCTACAACGA AGACTATA
20138





5684
GUCUGUUU A UGUAGAAA
9380
TTTCTACA GGCTAGCTACAACGA AAACAGAC
20139





5686
CUGUUUAU G UAGAAACA
9381
TGTTTCTA GGCTAGCTACAACGA ATAAACAG
20140





5692
AUGUAGAA A CAAAUGUA
9382
TACATTTG GGCTAGCTACAACGA TTCTACAT
20141





5696
AGAAACAA A UGUAAUAU
9383
ATATTACA GGCTAGCTACAACGA TTGTTTCT
20142





5698
AAACAAAU G UAAUAUAU
9384
ATATATTA GGCTAGCTACAACGA ATTTGTTT
20143





5701
CAAAUGUA A UAUAUUAA
9385
TTAATATA GGCTAGCTACAACGA TACATTTG
20144





5703
AAUGUAAU A UAUUAAAG
9386
CTTTAATA GGCTAGCTACAACGA ATTACATT
20145





5705
UGUAAUAU A UUAAAGCC
9387
GGCTTTAA GGCTAGCTACAACGA ATATTACA
20146





5711
AUAUUAAA G CCUUAUAU
9388
ATATAAGG GGCTAGCTACAACGA TTTAATAT
20147





5716
AAAGCCUU A UAUAUAAU
9389
ATTATATA GGCTAGCTACAACGA AAGGCTTT
20148





5718
AGCCUUAU A UAUAAUGA
9390
TCATTATA GGCTAGCTACAACGA ATAAGGCT
20149





5720
CCUUAUAU A UAAUGAAC
9391
GTTCATTA GGCTAGCTACAACGA ATATAAGG
20150





5723
UAUAUAUA A UGAACUUU
9392
AAAGTTCA GGCTAGCTACAACGA TATATATA
20151





5727
UAUAAUGA A CUUUGUAC
9393
GTACAAAG GGCTAGCTACAACGA TCATTATA
20152





5732
UGAACUUU G UACUAUUC
9394
GAATAGTA GGCTAGCTACAACGA AAAGTTCA
20153





5734
AACUUUGU A CUAUUCAC
9395
GTGAATAG GGCTAGCTACAACGA ACAAAGTT
20154





5737
UUUGUACU A UUCACAUU
9396
AATGTGAA GGCTAGCTACAACGA AGTACAAA
20155





5741
UACUAUUC A CAUUUUGU
9397
ACAAAATG GGCTAGCTACAACGA GAATAGTA
20156





5743
CUAUUCAC A UUUUGUAU
9398
ATACAAAA GGCTAGCTACAACGA GTGAATAG
20157





5748
CACAUUUU G UAUCAGUA
9399
TACTGATA GGCTAGCTACAACGA AAAATGTG
20158





5750
CAUUUUGU A UCAGUAUU
9400
AATACTGA GGCTAGCTACAACGA ACAAAATG
20159





5754
UUGUAUCA G UAUUAUGU
9401
ACATAATA GGCTAGCTACAACGA TGATACAA
20160





5756
GUAUCAGU A UUAUGUAG
9402
CTACATAA GGCTAGCTACAACGA ACTGATAC
20161





5759
UCAGUAUU A UGUAGCAU
9403
ATGCTACA GGCTAGCTACAACGA AATACTGA
20162





5761
AGUAUUAU G UAGCAUAA
9404
TTATGCTA GGCTAGCTACAACGA ATAATACT
20163





5764
AUUAUGUA G CAUAACAA
9405
TTGTTATG GGCTAGCTACAACGA TACATAAT
20164





5766
UAUGUAGC A UAACAAAG
9406
CTTTGTTA GGCTAGCTACAACGA GCTACATA
20165





5769
GUAGCAUA A CAAAGGUC
9407
GACCTTTG GGCTAGCTACAACGA TATGCTAC
20166





5775
UAACAAAG G UCAUAAUG
9408
CATTATGA GGCTAGCTACAACGA CTTTGTTA
20167





5778
CAAAGGUC A UAAUGCUU
9409
AAGCATTA GGCTAGCTACAACGA GACCTTTG
20168





5781
AGGUCAUA A UGCUUUCA
9410
TGAAAGCA GGCTAGCTACAACGA TATGACCT
20169





5783
GUCAUAAU G CUUUCAGC
9411
GCTGAAAG GGCTAGCTACAACGA ATTATGAC
20170





5790
UGCUUUCA G CAAUUGAU
9412
ATCAATTG GGCTAGCTACAACGA TGAAAGCA
20171





5793
UUUCAGCA A UUGAUGUC
9413
GACATCAA GGCTAGCTACAACGA TGCTGAAA
20172





5797
AGCAAUUG A UGUCAUUU
9414
AAATGACA GGCTAGCTACAACGA CAATTGCT
20173





5799
CAAUUGAU G UCAUUUUA
9415
TAAAATGA GGCTAGCTACAACGA ATCAATTG
20174





5802
UUGAUGUC A UUUUAUUA
9416
TAATAAAA GGCTAGCTACAACGA GACATCAA
20175





5807
GUCAUUUU A UUAAAGAA
9417
TTCTTTAA GGCTAGCTACAACGA AAAATGAC
20176





5815
AUUAAAGA A CAUUGAAA
9418
TTTCAATG GGCTAGCTACAACGA TCTTTAAT
20177





5817
UAAAGAAC A UUGAAAAA
9419
TTTTTCAA GGCTAGCTACAACGA GTTCTTTA
20178






Input Sequence= AF035121. Cut Site = R/Y




Arm Length = 8. Core Sequence = GGCTAGCTACAACGA




AF035121 (Homo sapiens KDR/flk-1 protein mRNA, complete cds.; Acc# AF035121; 5830 bp)








[0362]

26






TABLE XXIII










Human KDR Ziuzyme and Substrate Sequence















Seq ID

Seq ID



Pos
Substrate
No
Zinzyme
No















25
CCGGGAGA G CGGUCAGU
8365
ACUGACCG GCCGAAAGGCGAGUGAGGUCU UCUCCCGG
20179






28
GGAGAGCG G UCAGUGUG
8366
CACACUGA GCCGAAAGGCGAGUGAGGUCU CGCUCUCC
20180





32
AGCGGUCA G UGUGUGGU
8367
ACCACACA GCCGAAAGGCGAGUGAGGUCU UGACCGCU
20181





34
CGGUCAGU G UGUGGUCG
8368
CGACCACA GCCGAAAGGCGAGUGAGGUCU ACUGACCG
20182





36
GUCAGUGU G UGGUCGCU
8369
AGCGACCA GCCGAAAGGCGAGUGAGGUCU ACACUGAC
20183





39
AGUGUGUG G UCGCUGCG
8370
CGCAGCGA GCCGAAAGGCGAGUGAGGUCU CACACACU
20184





42
GUGUGGUC G CUGCGUUU
8371
AAACGCAG GCCGAAAGGCGAGUGAGGUCU GACCACAC
20185





45
UGGUCGCU G CGUUUCCU
8372
AGGAAACG GCCGAAAGGCGAGUGAGGUCU AGCGACCA
20186





47
GUCGCUGC G UUUCCUCU
8373
AGAGGAAA GCCGAAAGGCGAGUGAGGUCU GCAGCGAC
20187





56
UUUCCUCU G CCUGCGCC
8374
GGCGCAGG GCCGAAAGGCGAGUGAGGUCU AGAGGAAA
20188





60
CUCUGCCU G CGCCGGGC
8375
GCCCGGCG GCCGAAAGGCGAGUGAGGUCU AGGCAGAG
20189





62
CUGCCUGC G CCGGGCAU
8376
AUGCCCGG GCCGAAAGGCGAGUGAGGUCU GCAGGCAG
20190





67
UGCGCCGG G CAUCACUU
8377
AAGUGAUG GCCGAAAGGCGAGUGAGGUCU CCGGCGCA
20191





76
CAUCACUU G CGCGCCGC
8380
GCGGCGCG GCCGAAAGGCGAGUGAGGUCU AAGUGAUG
20192





78
UCACUUGC G CGCCGCAG
8381
CUGCGGCG GCCGAAAGGCGAGUGAGGUCU GCAAGUGA
20193





80
ACUUGCGC G CCGCAGAA
8382
UUCUGCGG GCCGAAAGGCGAGUGAGGUCU GCGCAAGU
20194





83
UGCGCGCC G CAGAAAGU
8383
ACUUUCUG GCCGAAAGGCGAGUGAGGUCU GGCGCGCA
20195





90
CGCAGAAA G UCCGUCUG
8384
CAGACGGA GCCGAAAGGCGAGUGAGGUCU UUUCUGCG
20196





94
GAAAGUCC G UCUGGCAG
8385
CUGCCAGA GCCGAAAGGCGAGUGAGGUCU GGACUUUC
20197





99
UCCGUCUG G CAGCCUGG
8386
CCAGGCUG GCCGAAAGGCGAGUGAGGUCU CAGACGGA
20198





102
GUCUGGCA G CCUGGAUA
8387
UAUCCAGG GCCGAAAGGCGAGUGAGGUCU UGCCAGAC
20199





124
UCCUACCG G CACCCGCA
8391
UGCGGGUG GCCGAAAGGCGAGUGAGGUCU CGGUAGGA
20200





130
CGGCACCC G CAGACGCC
8393
GGCGUCUG GCCGAAAGGCGAGUGAGGUCU GGGUGCCG
20201





136
CCGCAGAC G CCCCUGCA
8395
UGCAGGGG GCCGAAAGGCGAGUGAGGUCU GUCUGCGG
20202





142
ACGCCCCU G CAGCCGCC
8396
GGCGGCUG GCCGAAAGGCGAGUGAGGUCU AGGGGCGU
20203





145
CCCCUGCA G CCGCCGGU
8397
ACCGGCGG GCCGAAAGGCGAGUGAGGUCU UGCAGGGG
20204





148
CUGCAGCC G CCGGUCGG
8398
CCGACCGG GCCGAAAGGCGAGUGAGGUCU GGCUGCAG
20205





152
AGCCGCCG G UCGGCGCC
8399
GGCGCCGA GCCGAAAGGCGAGUGAGGUCU CGGCGGCU
20206





156
GCCGGUCG G CGCCCGGG
8400
CCCGGGCG GCCGAAAGGCGAGUGAGGUCU CGACCGGC
20207





158
CGGUCGGC G CCCGGGCU
8401
AGCCCGGG GCCGAAAGGCGAGUGAGGUCU GCCGACCG
20208





164
GCGCCCGG G CUCCCUAG
8402
CUAGGGAG GCCGAAAGGCGAGUGAGGUCU CCGGGCGC
20209





172
GCUCCCUA G CCCUGUGC
8403
GCACAGGG GCCGAAAGGCGAGUGAGGUCU UAGGGAGC
20210





177
CUAGCCCU G UGCGCUCA
8404
UGAGCGCA GCCGAAAGGCGAGUGAGGUCU AGGGCUAG
20211





179
AGCCCUGU G CGCUCAAC
8405
GUUGAGCG GCCGAAAGGCGAGUGAGGUCU ACAGGGCU
20212





181
CCCUGUGC G CUCAACUG
8406
CAGUUGAG GCCGAAAGGCGAGUGAGGUCU GCACAGGG
20213





189
GCUCAACU G UCCUGCGC
8408
GCGCAGGA GCCGAAAGGCGAGUGAGGUCU AGUUGAGC
20214





194
ACUGUCCU G CGCUGCGG
8409
CCGCAGCG GCCGAAAGGCGAGUGAGGUCU AGGACAGU
20215





196
UGUCCUGC G CUGCGGGG
8410
CCCCGCAG GCCGAAAGGCGAGUGAGGUCU GCAGGACA
20216





199
CCUGCGCU G CGGGGUGC
8411
GCACCCCG GCCGAAAGGCGAGUGAGGUCU AGCGCAGG
20217





204
GCUGCGGG G UGCCGCGA
8412
UCGCGGCA GCCGAAAGGCGAGUGAGGUCU CCCGCAGC
20218





206
UGCGGGGU G CCGCGAGU
8413
ACUCGCGG GCCGAAAGGCGAGUGAGGUCU ACCCCGCA
20219





209
GGGGUGCC G CGAGUUCC
8414
GGAACUCG GCCGAAAGGCGAGUGAGGUCU GGCACCCC
20220





213
UGCCGCGA G UUCCACCU
8415
AGGUGGAA GCCGAAAGGCGAGUGAGGUCU UCGCGGCA
20221





224
CCACCUCC G CGCCUCCU
8417
AGGAGGCG GCCGAAAGGCGAGUGAGGUCU GGAGGUGG
20222





226
ACCUCCGC G CCUCCUUC
8418
GAAGGAGG GCCGAAAGGCGAGUGAGGUCU GCGGAGGU
20223





244
CUAGACAG G CGCUGGGA
8420
UCCCAGCG GCCGAAAGGCGAGUGAGGUCU CUGUCUAG
20224





246
AGACAGGC G CUGGGAGA
8421
UCUCCCAG GCCGAAAGGCGAGUGAGGUCU GCCUGUCU
20223





263
AAGAACCG G CUCCCGAG
8423
CUCGGGAG GCCGAAAGGCGAGUGAGGUCU CGGUUCUU
20226





271
GCUCCCGA G UUCUGGGC
8424
GCCCAGAA GCCGAAAGGCGAGUGAGGUCU UCGGGAGC
20227





278
AGUUCUGG G CAUUUCGC
8425
GCGAAAUG GCCGAAAGGCGAGUGAGGUCU CCAGAACU
20228





285
GGCAUUUC G CCCGGCUC
8427
GAGCCGGG GCCGAAAGGCGAGUGAGGUCU GATAUGCC
20229





290
UUCGCCCG G CUCGAGGU
8428
ACCUCCAG GCCGAAAGGCGAGUGAGGUCU CGGGCGAA
20230





297
GGCUCGAG G UGCAGGAU
8429
AUCCUGCA GCCGAAAGGCGAGUGAGGUCU CUCGAGCC
20231





299
CUCGAGGU G CAGGAUGC
8430
GCAUCCUG GCCGAAAGGCGAGUGAGGUCU ACCUCGAG
20232





306
UGCAGGAU G CAGAGCAA
8432
UUGCUCUG GCCGAAAGGCGAGUGAGGUCU AUCCUGCA
20233





311
GAUGCAGA G CAAGGUGC
8433
GCACCUUG GCCGAAAGGCGAGUGAGGUCU UCUGCAUC
20234





316
AGAGCAAG G UGCUGCUG
8434
CAGCAGCA GCCGAAAGGCGAGUGAGGUCU CUUGCUCU
20235





318
AGCAAGGU G CUGCUGGC
8435
GCCAGCAG GCCGAAAGGCGAGUGAGGUCU ACCUUGCU
20236





321
AAGGUGCU G CUGGCCGU
8436
ACGGCCAG GCCGAAAGGCGAGUGAGGUCU AGCACCUU
20237





325
UGCUGCUG G CCGUCGCC
8437
GGCGACGG GCCGAAAGGCGAGUGAGGUCU CAGCAGCA
20238





328
UGCUGGCC G UCGCCCUG
8438
CAGGGCGA GCCGAAAGGCGAGUGAGGUCU GGCCAGCA
20239





331
UGGCCGUC G CCCUGUGG
8439
CCACAGGG GCCGAAAGGCGAGUGAGGUCU GACGGCCA
20240





336
GUCGCCCU G UGGCUCUG
8440
CAGAGCCA GCCGAAAGGCGAGUGAGGUCU AGGGCGAC
20241





339
GCCCUGUG G CUCUGCGU
8441
ACGCAGAG GCCGAAAGGCGAGUGAGGUCU CACAGGGC
20242





344
GUGGCUCU G CGUGGAGA
8442
UCUCCACG GCCGAAAGGCGAGUGAGGUCU AGAGCCAC
20243





346
GGCUCUGC G UGGAGACC
8443
GGUCUCCA GCCGAAAGGCGAGUGAGGUCU GCAGAGCC
20244





358
AGACCCGG G CCGCCUCU
8445
AGAGGCGG GCCGAAAGGCGAGUGAGGUCU CCGGGUCU
20245





361
CCCGGGCC G CCUCUGUG
8446
CACAGAGG GCCGAAAGGCGAGUGAGGUCU GGCCCGGG
20246





367
CCGCCUCU G UGGGUUUG
8447
CAAACCCA GCCGAAAGGCGAGUGAGGUCU AGAGGCGG
20247





371
CUCUGUGG G UUUGCCUA
8448
UAGGCAAA GCCGAAAGGCGAGUGAGGUCU CCACAGAG
20248





375
GUGGGUUU G CCUAGUGU
8449
ACACUAGG GCCGAAAGGCGAGUGAGGUCU AAACCCAC
20249





380
UUUGCCUA G UGUUUCUC
8450
GAGAAACA GCCGAAAGGCGAGUGAGGUCU UAGGCAAA
20250





382
UGCCUAGU G UUUCUCUU
8451
AAGAGAAA GCCGAAAGGCGAGUGAGGUCU ACUAGGCA
20251





396
CUUGAUCU G CCCAGGCU
8453
AGCCUGGG GCCGAAAGGCGAGUGAGGUCU AGAUCAAG
20252





402
CUGCCCAG G CUCAGCAU
8454
AUGCUGAG GCCGAAAGGCGAGUGAGGUCU CUGGGCAG
20253





407
CAGGCUCA G CAUACAAA
8455
UUUGUAUG GCCGAAAGGCGAGUGAGGUCU UGAGCCUG
20254





436
CAAUUAAG G CUAAUACA
8458
UGUAUUAG GCCGAAAGGCGAGUGAGGUCU CUUAAUUG
20255





461
AAUUACUU G CAGGGGAC
8462
GUCCCCUG GCCGAAAGGCGAGUGAGGUCU AAGUAAUU
20256





486
UUGGACUG G CUUUGGCC
8466
GGCCAAAG GCCGAAAGGCGAGUGAGGUCU CAGUCCAA
20257





492
UGGCUUUG G CCCAAUAA
8467
UUAUUGGG GCCGAAAGGCGAGUGAGGUCU CAAAGCCA
20258





506
UAAUCAGA G UGGCAGUG
8470
CACUGCCA GCCGAAAGGCGAGUGAGGUCU UCUGAUUA
20259





509
UCAGAGUG G CAGUGAGC
8471
GCUCACUG GCCGAAAGGCGAGUGAGGUCU CACUCUGA
20260





512
GAGUGGCA G UGAGCAAA
8472
UUUGCUCA GCCGAAAGGCGAGUGAGGUCU UGCCACUC
20261





516
GGCAGUGA G CAAAGGGU
8473
ACCCUUUG GCCGAAAGGCGAGUGAGGUCU UCACUGCC
20262





523
AGCAAAGG G UGGAGGUG
8474
CACCUCCA GCCGAAAGGCGAGUGAGGUCU CCUUUGCU
20263





529
GGGUGGAG G UGACUGAG
8475
CUCAGUCA GCCGAAAGGCGAGUGAGGUCU CUCCACCC
20264





537
GUGACUGA G UGCAGCGA
8477
UCGCUGCA GCCGAAAGGCGAGUGAGGUCU UCAGUCAC
20265





539
GACUGAGU G CAGCGAUG
8478
CAUCGCUG GCCGAAAGGCGAGUGAGGUCU ACUCAGUC
20266





542
UGAGUGCA G CGAUGGCC
8479
GGCCAUCG GCCGAAAGGCGAGUGAGGUCU UGCACUCA
20267





548
CAGCGAUG G CCUCUUCU
8481
AGAAGAGG GCCGAAAGGCGAGUGAGGUCU CAUCGCUG
20268





557
CCUCUUCU G UAAGACAC
8482
GUGUCUUA GCCGAAAGGCGAGUGAGGUCU AGAAGAGG
20269





580
UUCCAAAA G UGAUCGGA
8485
UCCGAUCA GCCGAAAGGCGAGUGAGGUCU UUUUGGAA
20270





601
ACACUGGA G CCUACAAG
8489
CUUGUAGG GCCGAAAGGCGAGUGAGGUCU UCCAGUGU
20271





609
GCCUACAA G UGCUUCUA
8490
UAGAAGCA GCCGAAAGGCGAGUGAGGUCU UUGUAGGC
20272





611
CUACAAGU G CUUCUACC
8491
GGUAGAAG GCCGAAAGGCGAGUGAGGUCU ACUUGUAG
20273





634
CUGACUUG G CCUCGGUC
8494
GACCGAGG GCCGAAACGCGAGUGAGGUCU CAAGUCAG
20274





640
UGGCCUCG G UCAUUUAU
8495
AUAAAUGA GCCGAAAGGCGAGUGAGGUCU CGAGGCCA
20275





649
UCAUUTUU G UCUAUGUU
8496
AACAUAGA GCCGAAAGGCGAGUGAGGUCU AUAAAUGA
20276





655
AUGUCUAU G UUCAAGAU
8497
AUCUUGAA GCCGAAAGGCGAGUGAGGUCU AUAGACAU
20277





682
CAUUUAUU G CUUCUGUU
8500
AACAGAAG GCCGAAAGGCGAGUGAGGUCU AAUAAAUG
20278





688
UUGCUUCU G UUAGUGAC
8501
GUCACUAA GCCGAAAGGCGAGUGAGGUCU AGAAGCAA
20279





692
UUCUGUUA G UGACCAAC
8502
GUUGGUCA GCCGAAAGGCGAGUGAGGUCU UAACAGAA
20280





706
AACAUGGA G UCGUGUAC
8505
GUACACGA GCCGAAAGGCGAGUGAGGUCU UCCAUGUU
20281





709
AUGGAGUC G UGUACAUU
8506
AAUGUACA GCCGAAAGGCGAGUGAGGUCU GACUCCAU
20282





711
GGAGUCGU G UACAUUAC
8507
GUAAUGUA GCCGAAAGGCGAGUGAGGUCU ACGACUCC
20283





739
ACAAAACU G UGGUGAUU
8511
AAUCACCA GCCGAAAGGCGAGUGAGGUCU AGUUUUGU
20284





742
AAACUGUG G UGAUUCCA
8512
UGGAAUCA GCCGAAAGGCGAGUGAGGUCU CACAGUUU
20285





752
GAUUCCAU G UCUCGGGU
8514
ACCCGAGA GCCGAAAGGCGAQUGAGGUCU AUGGAAUC
20286





759
UGUCUCGG G UCCAUUUC
8515
GAAAUGGA GCCGAAAGGCGAGUGAGGUCU CCGAGACA
20287





778
AUCUCAAC G UGUCACUU
8518
AAGUGACA GCCGAAAGGCGAGUGAGGUCU GUUGAGAU
20288





780
CUCAACGU G UCACUUUG
8519
CAAAGUGA GCCGAAAGGCGAGUGAGGUCU ACGUUGAG
20289





788
GUCACUUU G UGCAAGAU
8520
AUCUUGCA GCCGAAAGGCGAGUGAGGUCU AAAGUGAC
20290





790
CACUUUGU G CAAGAUAC
8521
GUAUCUUG GCCGAAAGGCGAGUGAGGUCU ACAAAGUG
20291





814
AGAGAUUU G UUCCUGAU
8524
AUCAGGAA GCCGAAAGGCGAGUGAGGUCU AAAUCUCU
20292





824
UCCUGAUG G UAACAGAA
8526
UUCUGUUA GCCGAAAGGCGAGUGAGGUCU CAUCAGGA
20293





845
CUGGGACA G CAAGAAGG
8530
CCUUCUUG GCCGAAAGGCGAGUGAGGUCU UGUCCCAG
20294





854
CAAGAAGG G CUUUACUA
8531
UAGUAAAG GCCGAAAGGCGAGUGAGGUCU CCUUCUUG
20295





869
UAUUCCCA G CUACAUGA
8532
UCAUGUAG GCCGAAAGGCGAGUGAGGUCU UGGGAAUA
20296





881
CAUGAUCA G CUAUGCUG
8534
CAGCAUAG GCCGAAAGGCGAGUGAGGUCU UGAUCAUG
20297





886
UCAGCUAU G CUGGCAUG
8535
CAUGCCAG GCCGAAAGGCGAGUGAGGUCU AUAGCUGA
20298





890
CUAUGCUG G CAUGGUCU
8536
AGACCAUG GCCGAAAGGCGAGUGAGGUCU CAGCAUAG
20299





895
CUGGCAUG G UCUUCUGU
8537
ACAGAAGA GCCGAAAGGCGAGUGAGGUCU CAUGCCAG
20300





902
GGUCUUCU G UGAAGCAA
8538
UUGCUUCA GCCGAAAGGCGAGUGAGGUCU AGAAGACC
20301





907
UCUGUGAA G CAAAAAUU
8539
AAUUUUUG GCCGAAAGGCGAGUGAGGUCU UUCACAGA
20302





926
UGAUGAAA G UUACCAGU
8543
ACUGGUAA GCCGAAAGGCGAGUGAGGUCU UUUCAUCA
20303





933
AGUUACCA G UCUAUUAU
8544
AUAAUAGA GCCGAAAGGCGAGUGAGGUCU UGGUAACU
20304





942
UCUAUUAU G UACAUAGU
8545
ACUAUGUA GCCGAAAGGCGAGUGAGGUCU AUAAUAGA
20305





949
UGUACAUA G UUGUCGUU
8546
AACGACAA GCCGAAAGGCGAGUGAGGUCU UAUGUACA
20306





952
ACAUAGUU G UCGUUGUA
8547
UACAACGA GCCGAAAGGCGAGUGAGGUCU AACUAUGU
20307





955
UAGUUGUC G UUGUAGGG
8548
CCCUACAA GCCGAAAGGCGAGUGAGGUCU GACAACUA
20308





958
UUGUCGUU G UAGGGUAU
8549
AUACCCUA GCCGAAAGGCGAGUGAGGUCU AACGACAA
20309





963
GUUGUAGG G UAUAGGAU
8550
AUCCUAUA GCCGAAAGGCGAGUGAGGUCU CCUACAAC
20310





979
UUUAUGAU G UGGUUCUG
8553
CAGAACCA GCCGAAAGGCGAGUGAGGUCU AUCAUAAA
20311





982
AUGAUGUG G UUCUGAGU
8554
ACUCAGAA GCCGAAAGGCGAGUGAGGUCU CACAUCAU
20312





989
GGUUCUGA G UCCGUCUC
8555
GAGACGGA GCCGAAAGGCGAGUGAGGUCU UCAGAACC
20313





993
CUGAGUCC G UCUCAUGG
8556
CCAUGAGA GCCGAAAGGCGAGUGAGGUCU GGACUCAG
20314





1015
AACUAUCU G UUGGAGAA
8559
UUCUCCAA GCCGAAAGGCGAGUGAGGUCU AGAUAGUU
20315





1026
GGAGAAAA G CUUGUCUU
8560
AAGACAAG GCCGAAAGGCGAGUGAGGUCU UUUUCUCC
20316





1030
AAAAGCUU G UCU1AAAU
8561
AUUUAAGA GCCGAAAGGCGAGUGAGGUCU AAGCUUUU
20317





1040
CUUAAAUU G UACAGCAA
8563
UUGCUGUA GCCGAAAGGCGAGUGAGGUCU AAUUUAAG
20318





1045
AUUGUACA G CAAGAACU
8564
AGUUCUUG GCCGAAAGGCGAGUGAGGUCU UGUACAAU
20319





1063
AACUAAAU G UGGGGAUU
8568
AAUCCCCA GCCGAAAGGCGAGUGAGGUCU AUUUAGUU
20320





1101
UCUUCGAA G CAUCAGCA
8573
UCCUGAUG GCCGAAAGGCGAGUGAGGUCU UUCGAAGA
20321





1107
AAGCAUCA G CAUAAGAA
8574
UUCUUAUG GCCGAAAGGCGAGUGAGGUCU UGAUGCUU
20322





1120
AGAAACUU G UAAACCGA
8576
UCGGUUUA GCCGAAAGGCGAGUGAGGUCU AAGUUUCU
20323





1143
AAAACCCA G UCUGGGAG
8580
CUCCCAGA GCCGAAAGGCGAGUGAGGUCU UGGGUUUU
20324





1151
GUCUGGGA G UGAGAUGA
8581
UCAUCUCA GCCGAAAGGCGAGUGAGGUCU UCCCAGAC
20325





1172
AUUUUUGA G CACCUEUA
8584
UUAAGGUG GCCGAAAGGCGAGUGAGGUCU UCAAAAAU
20326





1190
UAUAGAUG G UGUAACCC
8587
GGGUUACA GCCGAAAGGCGAGUGAGGUCU CAUCUAUA
20327





1192
UAGAUGGU G UAACCCGG
8588
CCGGGUUA GCCGAAAGGCGAGUGAGGUCU ACCAUCUA
20328





1202
AACCCGGA G UGACCAAG
8590
CUUGGUCA GCCGAAAGGCGAGUGAGGUCU UCCGGGUU
20329





1215
CAAGGAUU G UACACCUG
8593
CAGGUGUA GCCGAAAGGCGAGUGAGGUCU AAUCCUUG
20330





1223
GUACACCU G UGCAGCAU
8594
AUGCUGCA GCCGAAAGGCGAGUGAGGUCU AGGUGUAC
20331





1225
ACACCUGU G CAGCAUCC
8595
GGAUGCUG GCCGAAAGGCGAGUGAGGUCU ACAGGUGU
20332





1228
CCUGUGCA G CAUCCAGU
8596
ACUGGAUG GCCGAAAGGCGAGUGAGGUCU UGCACAGG
20333





1235
AGCAUCCA G UGGGCUGA
8597
UCAGCCCA GCCGAAAGGCGAGUGAGGUCU UGGAUGCU
20334





1239
UCCAGUGG G CUGAUGAC
8598
GUCAUCAG GCCGAAAGGCGAGUGAG3UCU UCACUGGA
20335





1259
GAAGAACA G CACAUUUG
8602
CAAAUGUG GCCGAAAGGCGAGUGAGGUCU UGUUCUUC
20336





1267
GCACAUUU G UCAGGGUC
8603
GACCCUGA GCCGAAAGGCGAGUGAGGUCU AAAUGUGC
20337





1273
UUGUCAGG G UCCAUGAA
8604
UUCAUGGA GCCGAAAGGCGAGUGAGGUCU CCUGACAA
20338





1291
AACCUUUU G UUGCUUUU
8606
AAAAGCAA GCCGAAAGGCGAGUGAGGUCU AAAAGGUU
20339





1294
CUUUUGUU G CUUUUGGA
8607
UCCAAAAG GCCGAAAGGCGAGUGAGGUCU AACAAAAG
20340





1304
UUUUGGAA G UGGCAUGG
8608
CCAUGCCA GCCGAAAGGCGAGUGAGGUCU UUCCAAAA
20341





1307
UGGAAGUG G CAUGGAAU
8609
AUUCCAUG GCCGAAAGGCGAGUGAGGUCU CACUUCCA
20342





1321
AAUCUCUG G UGGAAGCC
8611
GGCUUCCA GCCGAAAGGCGAGUGAGGUCU CAGAGAUG
20343





1327
UGGUGGAA G CCACGGUG
8612
CACCGUGG GCCGAAAGGCGAGUGAGGUCU UUCCACCA
20344





1333
AAGCCACG G UGGGGGAG
8613
CUCCCCCA GCCGAAAGGCGAGUGAGGUCU CGUGGCUU
20345





1341
GUGGGGGA G CGUGUCAG
8614
CUGACACG GCCGAAAGGCGAGUGAGGUCU UCCCCCAC
20346





1343
GGGGGAGC G UGUCAGAA
8615
UUCUGACA GCCGAAAGGCGAGUGAGGUCU GCUCCCCC
20347





1345
GGGAGCGU G UCAGAAUC
8616
GACUCUGA GCCGAAAGGCGAGUGAGGUCU ACGCUCCC
20348





1357
GAAUCCCU G CGAAGUAC
8618
GUACUUCG GCCGAAAGGCGAGUGAGGUCU AGGGAUUC
20349





1362
CCUGCGAA G UACCUUGG
8619
CCAAGGUA GCCGAAAGGCGAGUGAGGUCU UUCGCAGG
20350





1370
GUACCUUG G UUACCCAC
8620
GUGGGUAA GCCGAAAGGCGAGUGAGGUCU CAAGGUAC
20351





1395
AUAAAAUG G UAUAAAAA
8623
UUUUUAUA GCCGAAAGGCGAGUGAGGUCU CAUUUUAU
20352





1419
CCCCUUGA G UCCAAUCA
8626
UGAUUGGA GCCGAAAGGCGAGUGAGGUCU UCAAGGGG
20353





1438
CAAUEUAA G CGGGGCAU
8629
AUGCCCCG GCCGAAAGGCGAGUGAGGUCU UUEUAUUG
20354





1443
AAAGCGGG G CAUGUACU
8630
AGUACAUG GCCGA1AGGCGAGUGAGGUCU CCCGCUUU
20355





1447
CGGGGCAU G UACUGACG
8631
CGUCAGUA GCCGAAAGGCGAGUGAGGUCU AUGCCCCG
20356





1465
UUAUGGAU G UGAGUGAA
8634
UUCACUCA GCCGAAAGGCGAGUGAGGUCU UUCCAUAA
20357





1469
GGAAGUGA G UGAAAGAG
8635
CUCUUUCA GCCGAAAGGCGAGUGAGGUCU UCACUUCC
20358





1495
AUUACACU G UCAUCCUG
8638
AAGGAUGA GCCGAAAGGCGAGUGAGGUCU AGUGUAAU
20359





1527
AAGGAGAA G CAGAGCCA
8640
UGGCUCUG GCCGAAAGGCGAGUGAGGUCU UUCUCCUU
20360





1532
GAAGCAGA G CCAUGUGG
8641
CCACAUGG GCCGAAAGGCGAGUGAGGUCU UCUGCUUC
20361





1537
AGAGCCAU G UGGUCUCU
8642
AGAGACCA GCCGAAAGGCGAGUGAGGUCU AUGGCUCU
20362





1540
GCCAUGUG G UCUCUCUG
8643
CAGAGAGA GCCGAAAGGCGAGUGAGGUCU CACAUGGC
20363





1549
UCUCUCUG G UUGUGUAU
8644
AUACACAA GCCGAAAGGCGAGUGAGGUCU CAGAGAGA
20364





1552
CUCUGGUU G UGUAUGUC
8645
GACAUACA GCCGAAAGGCGAGUGAGGUCU AACCAGAG
20365





1554
CUGGUUGU G UAUGUCCC
8646
GGGACAUA GCCGAAAGGCGAGUGAGGUCU ACAACCAG
20366





1558
UUGUGUAU G UCCCACCC
8647
GGCUCGCA GCCGAAACGCGAGUGAGGUCU AUACACAA
20367





1574
CCAGAUUG G UGAGAAAU
8649
AUUUCUCA GCCGAAAGGCGAGUGAGGUCU CAAUCUGG
20368





1597
UCUCUCCU G UGGAUUCC
8652
GGAAUCCA CCCGAAAGGCGAGUGAGGUCU AGGAGAGA
20369





1611
UCCUACCA G UACGGCAC
8654
GUGCCGUA GCCGAAACGCGAGUGAGGUCU UGGUAGGA
20370





1616
CCAGUACG G CACCACUC
8655
GAGUGGUG GCCGAAAGGCGAGUGAGGUCU CGUACUGG
20371





1629
ACUCAAAC G CUGACAUG
8657
CAUGUCAG GCCGAAAGGCGAGUGAGGUCU GUUUGAGU
20372





1637
GCUGACAU G UACGGUCU
8659
AGACCGUA GCCGAAAGGCGAGUGAGGUCU AUGUCAGC
20373





1642
CAUGUACG G UCUAUGCC
8660
GGCAUAGA GCCGAAAGGCGAGUGAGGUCU CGUACAUG
20374





1648
CGGUCUAU G CCAUUCCU
8661
AGGAAUGG GCCGAAAGGCGAGUGAGGUCU AUAGACCG
20375





1662
CCUCCCCC G CAUCACAU
8662
AUGUGAUG GCCGAAAGGCGAGUGAGGUCU GGGGGAGG
20376





1677
AUCCACUG G UAUUGGCA
8663
UGCCAAUA GCCGAAAGGCGAGUGAGGUCU CAGUGGAU
20377





1683
UGGUAUUG G CAGUUGGA
8664
UCCAACUG GCCGAAAGGCGAGUGAGGUCU CAAUACCA
20378





1686
UAUUGGCA G UUGGAGGA
8665
UCCUCCAA GCCGAAAGGCGAGUGAGGUCU UGCCAAUA
20379





1698
GAGGAAGA G UGCGCCAA
8666
UUGGCGCA GCCGAAAGGCGAGUGAGGUCU UCUUCCUC
20380





1700
GGAAGAGU G CGCCAACG
8667
CGUUGGCG GCCGAAAGGCGAGUGAGGUCU ACUCUUCC
20381





1702
AAGAGUGC G CCAACGAG
8668
CUCGUUGG GCCGAAAGGCGAGUGAGGUCU GCACUCUU
20382





1710
GCCAACGA G CCCAGCCA
8670
UGGCUGGG GCCGAAAGGCGAGUGAGGUCU UCGUUGGC
20383





1715
CGAGCCCA G CCAAGCUG
8671
CAGCUUGG GCCGAAAGGCGAGUGAGGUCU UGGGCUCG
20384





1720
CCAGCCAA G CUGUCUCA
8672
UGAGACAG GCCGAAAGGCGAGUGAGGUCU UUGGCUGG
20385





1723
GCCAAGCU G UCUCAGUG
8673
CACUGAGA GCCGAAAGGCGAGUGAGGUCU AGCUUGGC
20386





1729
CUGUCUCA G UGACAAAC
8674
GUUUGUCA GCCGAAAGGCGAGUGAGGUCU UGAGACAG
20387





1748
AUACCCUU G UGAAGAAU
8677
AUUCUUCA GCCGAAAGGCGAGUGAGGUCU AAGGGUAU
20388





1763
AUGGAGAA G UGUGGAGG
8679
CCUCCACA GCCGAAAGGCGAGUGAGGUCU UUCUCCAU
20389





1765
GGAGAAGU G UGGAGGAC
8680
GUCCUCCA GCCGAAAGGCGAGUGAGGUCU ACUUCUCC
20390





1798
AAAUUGAA G UUAAUAAA
8684
UUUAUUAA GCCGAAAGGCGAGUGAGGUCU UUCAAUUU
20391





1816
AUCAAUUU G CUCUAAUU
8688
AAUUAGAG GCCGAAAGGCGAGUGAGGUCU AAAUUGAU
20392





1843
ACAAAACU G UAAGUACC
8692
GGUACUUA GCCGAAAGGCGAGUGAGGUCU AGUUUUGU
20393





1847
AACUGUAA G UACCCUUG
8693
CAAGGGUA GCCGAAAGGCGAGUGAGGUCU UUACAGUU
20394





1855
GUACCCUU G UUAUCCAA
8694
UUGGAUAA GCCGAAAGGCGAGUGAGGUCU AAGGGUAC
20395





1864
UUAUCCAA G CGGCAAAU
8695
AUUUGCCG GCCGAAAGGCGAGUGAGGUCU UUGGAUAA
20396





1867
UCCAAGCG G CAAAUGUG
8696
CACAUUUG GCCGAAAGGCGAGUGAGGUCU CGCUUGGA
20397





1873
CGGCAAAU G UGUCAGCU
8698
AGCUGACA GCCGAAAGGCGAGUGAGGUCU AUUUGCCG
20398





1875
GCAAAUGU G UCAGCUUU
8699
AAAGCUGA GCCGAAAGGCGAGUGAGGUCU ACAUUUGC
20399





1879
AUGUGUCA G CUUUGUAC
8700
GUACAAAG GCCGAAAGGCGAGUGAGGUCU UGACACAU
20400





1884
UCAGCUUU G UACAAAUG
8701
CAUUUGUA GCCGAAAGGCGAGUGAGGUCU AAAGCUGA
20401





1892
GUACAAAU G UGAAGCGG
8703
CCGCUUCA GCCGAAAGGCGAGUGAGGUCU AUUUGUAC
20402





1897
AAUGUGAA G CGGUCAAC
8704
GUUGACCG GCCGAAAGGCGAGUGAGGUCU UUCACAUU
20403





1900
GUGAAGCG G UCAACAAA
8705
UUUGUUGA GCCGAAAGGCGAGUGAGGUCU CGCUUCAC
20404





1909
UCAACAAA G UCGGGAGA
8707
UCUCCCGA GCCGAAAGGCGAGUGAGGUCU UUUGUUGA
20405





1927
GAGAGAGG G UGAUCUCC
8708
GGAGAUCA GCCGAAAGGCGAGUGAGGUCU CCUCUCUC
20406





1942
CCUUCCAC G UGACCAGG
8710
CCUGGUCA GCCGAAAGGCGAGUGAGGUCU GUGGAAGG
20407





1952
GACCAGGG G UCCUGAAA
8712
UUUCAGGA GCCGAAAGGCGAGUGAGGUCU CCCUGGUC
20408





1968
AUUACUUU G CAACCUGA
8714
UCAGGUUG GCCGAAAGGCGAGUGAGGUCU AAAGUAAU
20409





1980
CCUGACAU G CAGCCCAC
8717
GUGGGCUG GCCGAAAGGCGAGUGAGGUCU AUGUCAGG
20410





1983
GACAUGCA G CCCACUGA
8718
UCAGUGGG GCCGAAAGGCGAGUGAGGUCU UGCAUGUC
20411





1992
CCCACUGA G CAGGAGAG
8719
CUCUCCUG GCCGAAAGGCGAGUGAGGUCU UCAGUGGG
20412





2000
GCAGGAGA G CGUGUCUU
8720
AAGACACG GCCGAAAGGCGAGUGAGGUCU UCUCCUGC
20413





2002
AGGAGAGC G UGUCUUUG
8721
CAAAGACA GCCGAAAGGCGAGUGAGGUCU GCUCUCCU
20414





2004
GAGAGCGU G UCUUUGUG
8722
CACAAAGA GCCGAAAGGCGAGUGAGGUCU ACGCUCUC
20415





2010
GUGUCUUU G UGGUGCAC
8723
GUGCACCA GCCGAAAGGCGAGUGAGGUCU AAAGACAC
20416





2013
UCUUUGUG G UCCACUGC
8724
GCAGUGCA GCCGAAAGGCGAGUGAGGUCU CACAAAGA
20417





2015
UUUGUGGU G CACUGCAG
8725
CUGCAGUG GCCGAAAGGCGAGUGAGGUCU ACCACAAA
20418





2020
GGUGCACU G CAGACAGA
8726
UCUGUCUG GCCGAAAGGCGAGUGAGGUCU AGUGCACC
20419





2034
AGAUCUAC G UUUGAGAA
8729
UUCUCAAA GCCGAAAGGCGAGUGAGGUCU GUAGAUCU
20420





2052
CUCACAUG G UACAAGCU
8731
AGCUUGUA GCCGAAAGGCGAGUGAGGUCU CAUGUGAG
20421





2058
UGGUACAA G CUUGGCCC
8732
GGGCCAAG GCCGAAAGGCGAGUGAGGUCU UUGUACCA
20422





2063
CAAGCUUG G CCCACAGC
8733
GCUGUGGG GCCGAAAGGCGAGUGAGGUCU CAAGCUUG
20423





2070
GGCCCACA G CCUCUGCC
8734
GGCAGAGG GCCGAAAGGCGAGUGAGGUCU UGUGGGCC
20424





2076
CAGCCUCU G CCAAUCCA
8735
UGGAUUGG GCCGAAAGGCGAGUGAGGUCU AGAGGCUG
20425





2086
CAAUCCAU G UGGGAGAG
8737
CUCUCCCA GCCGAAAGGCGAGUGAGGUCU AUGGAUUG
20426





2094
GUGGGAGA G UUGCCCAC
8738
GUGGGCAA GCCGAAAGGCGAGUGAGGUCU UCUCCCAC
20427





2097
GGAGAGUU G CCCACACC
8739
GGUGUGGG GCCGAAAGGCGAGUGAGGUCU AACUCUCC
20428





2107
CCACACCU G UUUGCAAG
8740
CUUGCAAA GCCGAAAGGCGAGUGAGGUCU AGGUGUGG
20429





2111
ACCUGUUU G CAAGAACU
8741
AGUUCUUG GCCGAAAGGCGAGUGAGGUCU AAACAGGU
20430





2143
AAUUGAAU G CCACCAUG
8746
CAUGGUGG GCCGAAAGGCGAGUGAGGUCU AUUCAAUU
20431





2151
GCCACCAU G UUCUCUAA
8747
UUAGAGAA GCCGAAAGGCGAGUGAGGUCU AUGGUGGC
20432





2162
CUCUAAUA G CACAAAUG
8749
CAUUUGUG GCCGAAAGGCGAGUGAGGUCU UAUEUGAG
20433





2187
AUCAUGGA G CUUAAGAA
8753
UUCUUAAG GCCGAAAGGCGAGUGAGGUCU UCCAUGAU
20434





2197
UUAAGAAU G CAUCCUUG
8755
CAAGGAUG GCCGAAAGGCGAGUGAGGUCU AUUCUUAA
20435





2205
GCAUCCUU G CAGGACCA
8756
UGGUCCUG GCCGAAAGGCGAGUGAGGUCU AAGGAUGC
20436





2224
GAGACUAU G UCUGCCUU
8759
AAGGCAGA GCCGAAAGGCGAGUGAGGUCU AUAGUCUC
20437





2228
CUAUGUCU G CCUUGCUC
8760
GAGCAAGG GCCGAAAGGCGAGUGAGGUCU AGACAUAG
20438





2233
UCUGCCUU G CUCAAGAC
8761
GUCUUGAG GCCGAAAGGCGAGUGAGGUCU AAGGCAGA
20439





2264
AAGACAUU G CGUGGUCA
8765
UGACCACG GCCGAAAGGCGAGUGAGGUCU AAUGUCUU
20440





2266
GACAUUGC G UGGUCAGG
8766
CCUGACCA GCCGAAAGGCGAGUGAGGUCU GCAAUGUC
20441





2269
AUUGCGUG G UCAGGCAG
8767
CUGCCUGA GCCGAAAGGCGAGUGAGGUCU CACGCAAU
20442





2274
GUGGUCAG G CAGCUCAC
8768
GUGAGCUG GCCGAAAGGCGAGUGAGGUCU CUGACCAC
20443





2277
GUCAGGCA G CUCACAGU
8769
ACUGUGAG GCCGAAAGGCGAGUGAGGUCU UGCCUGAC
20444





2284
AGCUCACA G UCCUAGAG
8770
CUCUAGGA GCCGAAAGGCGAGUGAGGUCU UGUGAGCU
20445





2292
GUCCUAGA G CGUGUGGC
8771
GCCACACG GCCGAAAGGCGAGUGAGGUCU UCUAGGAC
20446





2294
CCUAGAGC G UGUGGCAC
8772
GUGCCACA GCCGAAAGGCGAGUGAGGUCU GCUCUAGG
20447





2296
UAGAGCGU G UGGCACCC
8773
GGGUGCCA GCCGAAAGGCGAGUGAGGUCU ACGCUCUA
20448





2299
AGCGUGUG G CACCCACG
8774
CGUGGGUG GCCGAAAGGCGAGUGAGGUCU CACACGCU
20449





2339
GACGACAA G UAUUGGGG
8780
CCCCAAUA GCCGAAAGGCGAGUGAGGUCU UUGUCGUC
20450





2351
UGGGGAAA G CAUCGAAG
8781
CUUCGAUG GCCGAAAGGCGAGUGAGGUCU UUUCCCCA
20451





2359
GCAUCGAA G UCUCAUGC
8782
GCAUGAGA GCCGAAAGGCGAGUGAGGUCU UUCGAUGC
20452





2366
AGUCUCAU G CACGGCAU
8783
AUGCCGUG GCCGAAAGGCGAGUGAGGUCU AUGAGACU
20453





2371
CAUGCACG G CAUCUGGG
8784
CCCAGAUG GCCGAAAGGCGAGUGAGGUCU CGUGCAUG
20454





2400
CAGAUCAU G UGGUUUAA
8787
UUAAACCA GCCGAAAGGCGAGUGAGGUCU AUGAUCUG
20455





2403
AUCAUGUG G UUUAAAGA
8788
UCUUUAAA GCCGAAAGGCGAGUGAGGUCU CACAUGAU
20456





2425
AGACCCUU G UAGAAGAC
8792
GUCUUCUA GCCGAAAGGCGAGUGAGGUCU AAGGGUCU
20457





2438
AGACUCAG G CAUUGUAU
8794
AUACAAUG GCCGAAAGGCGAGUGAGGUCU CUGAGUCU
20458





2443
CAGGCAUU G UAUUGAAG
8795
CUUCAAUA GCCGAAAGGCGAGUGAGGUCU AAUGCCUG
20459





2477
CACUAUCC G CAGAGUGA
8799
UCACUCUG GCCGAAAGGCGAGUGAGGUCU GGAUAGUG
20460





2482
UCCGCAGA G UGAGGAAG
8800
CUUCCUCA GCCGAAAGGCGAGUGAGGUCU UCUGCGGA
20461





2501
GGACGAAG G CCUCUACA
8802
UGUAGAGG GCCGAAAGGCGAGUGAGGUCU CUUCGUCC
20462





2513
CUACACCU G CCAGGCAU
8803
AUGCCUGG GCCGAAAGGCGAGUGAGGUCU AGGUGUAG
20463





2518
CCUGCCAG G CAUGCAGU
8804
ACUGCAUG GCCGAAAGGCGAGUGAGGUCU CUGGCAGG
20464





2522
CCAGGCAU G CAGUGUUC
8805
GAACACUG GCCGAAAGGCGAGUGAGGUCU AUGCCUGG
20465





2525
GGCAUGCA G UGUUCUUG
8806
CAAGAACA GCCGAAAGGCGAGUGAGGUCU UGCAUGCC
20466





2527
CAUGCAGU G UUCUUGGC
8807
GCCAAGAA GCCGAAAGGCGAGUGAGGUCU ACUGCAUG
20467





2534
UGUUCUUG G CUGUGCAA
8808
UUGCACAG GCCGAAAGGCGAGUGAGGUCU CAAGAACA
20468





2537
UCUUGGCU G UGCAAAAG
8809
CUUUUGCA GCCGAAAGGCGAGUGAGGUCU AGCCAAGA
20469





2539
UUGGCUGU G CAAAAGUG
8810
CACUUUUG GCCGAAAGGCGAGUGAGGUCU ACAGCCAA
20470





2545
GUGCAAAA G UGGAGGCA
8811
UGCCUCCA GCCGAAAGGCGAGUGAGGUCU UUUUGCAC
20471





2551
AAGUGGAG G CAUUUUUC
8812
GAAAAAUG GCCGAAAGGCGAGUGAGGUCU CUCCACUU
20472





2570
AAUAGAAG G UGCCCAGG
8814
CCUGGGCA GCCGAAAGGCGAGUGAGGUCU CUUCUAUU
20473





2572
UAGAAGGU G CCCAGGAA
8815
UUCCUGGG GCCGAAAGGCGAGUGAGGUCU ACCUUCUA
20474





2608
UUAUUCUA G UAGGCACG
8819
CGUGCCUA GCCGAAAGGCGAGUGAGGUCU UAGAAUAA
20475





2612
UCUAGUAG G CACGGCGG
8820
CCGCCGUG GCCGAAAGGCGAGUGAGGUCU CUACUAGA
20476





2617
UAGGCACG G CGGUGAUU
8822
AAUCACCG GCCGAAAGGCGAGUGAGGUCU CGUGCCUA
20477





2620
GCACGGCG G UGAUUGCC
8823
GGCAAUCA GCCGAAAGGCGAGUGAGGUCU CGCCGUGC
20478





2626
CGGUGAUU G CCAUGUUC
8825
GAACAUGG GCCGAAAGGCGAGUGAGGUCU AAUCACCG
20479





2631
AUUGCCAU G UUCUUCUG
8826
CAGAAGAA GCCGAAAGGCGAGUGAGGUCU AUGGCAAU
20480





2640
UUCUUCUG G CUACUUCU
8827
AGAAGUAG GCCGAAAGGCGAGUGAGGUCU CAGAAGAA
20481





2650
UACUUCUU G UCAUCAUC
8828
GAUGAUGA GCCGAAAGGCGAGUGAGGUCU AAGAAGUA
20482





2668
UACGGACC G UUAAGCGG
8832
CCGCUUAA GCCGAAAGGCGAGUGAGGUCU GGUCCGUA
20483





2673
ACCGUUAA G CGGGCCAA
8833
UUGGCCCG GCCGAAAGGCGAGUGAGGUCU UUAACGGU
20484





2677
UUAAGCGG G CCAAUGGA
8834
UCCAUUGG GCCGAAAGGCGAGUGAGGUCU CCGCUUAA
20485





2702
GAAGACAG G CUACUUGU
8838
ACAAGUAG GCCGAAAGGCGAGUGAGGUCU CUGUCUUC
20486





2709
GGCUACUU G UCCAUCGU
8839
ACGAUGGA GCCGAAAGGCGAGUGAGGUCU AAGUAGCC
20487





2716
UGUCCAUC G UCAUGGAU
8840
AUCCAUGA GCCGAAAGGCGAGUGAGGUCU GAUGGACA
20488





2753
UGAACAUU G UGAACGAC
8846
GUCGUUCA GCCGAAAGGCGAGUGAGGUCU AAUGUUCA
20489





2763
GAACGACU G CCUUAUGA
8849
UCAUAAGG GCCGAAAGGCGAGUGAGGUCU AGUCGUUC
20490





2773
CUUAUGAU G CCAGCAAA
8851
UUUGCUGG GCCGAAAGGCGAGUGAGGUCU AUCAUAAG
20491





2777
UGAUGCCA G CAAAUGGG
8852
CCCAUUUG GCCGAAAGGCGAGUGAGGUCU UGGCAUCA
20492





2802
AGAGACCG G CUGAAGCU
8856
AGCUUCAG GCCGAAAGGCGAGUGAGGUCU CGGUCUCU
20493





2808
CGGCUGAA G CUAGGUAA
8857
UUACCUAG GCCGAAAGGCGAGUGAGGUCU UUCAGCCG
20494





2813
GAAGCUAG G UAAGCCUC
8858
GAGGCUUA GCCGAAAGGCGAGUGAGGUCU CUAGCUUC
20495





2817
CUAGGUAA G CCUCUUGG
8859
CCAAGAGG GCCGAAAGGCGAGUGAGGUCU UUACCUAG
20496





2825
GCCUCUUG G CCGUGGUG
8860
CACCACGG GCCGAAAGGCGAGUGAGGUCU CAAGAGGC
20497





2828
UCUUGGCC G UGGUGCCU
8861
AGGCACCA GCCGAAAGGCGAGUGAGGUCU GGCCAAGA
20498





2831
UGGCCGUG G UGCCUUUG
8862
CAAAGGCA GCCGAAAGGCGAGUGAGGUCU CACGGCCA
20499





2833
GCCGUGGU G CCUUUGGC
8863
GCCAAAGG GCCGAAAGGCGAGUGAGGUCU ACCACGGC
20500





2840
UGCCUUUG G CCAAGUGA
8864
UCACUUGG GCCGAAAGGCGAGUGAGGUCU CAAAGGCA
20501





2845
UUGGCCAA G UGAUUGAA
8865
UUCAAUCA GCCGAAAGGCGAGUGAGGUCU UUGGCCAA
20502





2854
UGAUUGAA G CAGAUGCC
8867
GGCAUCUG GCCGAAAGGCGAGUGAGGUCU UUCAAUCA
20503





2860
AAGCAGAU G CCUUUGGA
8869
UCCAAAGG GCCGAAAGGCGAGUGAGGUCU AUCUGCUU
20504





2881
ACAAGACA G CAACUUGC
8873
GCAAGUUG GCCGAAAGGCGAGUGAGGUCU UGUCUUGU
20505





2888
AGCAACUU G CAGGACAG
8875
CUGUCCUG CCCGAAAGGCGAGUGAGGUCU AAGUUGCU
20506





2896
GCAGGACA G UAGCAGUC
8877
GACUGCUA GCCGAAAGGCGAGUGAGGUCU UGUCCUGC
20507





2899
CGACAGUA G CAGUCAAA
8878
UUUGACUG GCCGAAAGGCGAGUGAGGUCU UACUGUCC
20508





2902
CAGUAGCA G UCAAAAUG
8879
CAUUUUGA GCCGAAAGGCGAGUGAGGUCU UCCUACUG
20509





2910
GUCAAAAU G UUGAAAGA
8881
UCUUUCAA GCCGAAAGGCGAGUGACGUCU AUUUUGAC
20510





2923
AAGAACGA G CAACACAC
8882
GUGUGUUG GCCGAAAGGCGAGUGAGGUCU UCCUUCUU
20511





2933
AACACACA G UGAGCAUC
8884
GAUGCUCA GCCGAAAGGCGAGUGAGGUCU UGUGUGUU
20512





2937
CACAGUGA G CAUCGAGC
8885
GCUCCAUG GCCGAAAGGCGAGUGAGCUCU UCACUGUC
20513





2944
ACCAUCCA G CUCUCAUC
8886
CAUGAGAC GCCCAAACGCGACUGACGUCU UCCAUGCU
20514





2952
GCUCUCAU G UCUGAACU
8887
AGUUCAGA GCCGAAAGGCGACUGAGGUCU AUGAGAGC
20515





2981
UCAUAUUG G UCACCAUC
8890
GAUCCUGA GCCCAAACCCGACUGAGGUCU CAAUAUGA
20516





2995
AUCUCAAU G UGGUCAAC
8892
GUUGACCA GCCGAAAGGCGAGUGAGGUCU AUUGAGAU
20517





2998
UCAAUGUG G UCAACCUU
8893
AAGGUUGA GCCGAAAGGCGAGUGAGGUCU CACAUUGA
20518





3011
CCUUCUAG G UGCCUGUA
8895
UACAGGCA GCCGAAAGGCGAGUGAGGUCU CUAGAAGG
20519





3013
UUCUAGGU G CCUGUACC
8896
GGUACAGG GCCGAAAGGCGAGUGAGGUCU ACCUAGAA
20520





3017
AGGUGCCU G UACCAAGC
8897
GCUUGGUA GCCGAAAGGCGAGUGAGGUCU AGGCACCU
20521





3024
UGUACCAA G CCAGGAGG
8898
CCUCCUGG GCCGAAAGGCGAGUGAGGUCU UUGGUACA
20522





3033
CCAGGAGG G CCACUCAU
8899
AUCAGUGG GCCGAAAGGCGAGUCACGUCU CCUCCUGG
20523





3043
CACUCAUG G UGAUUGUG
8900
CACAAUCA GCCGAAAGGCGAGUGAGGUCU CAUGAGUG
20524





3049
UGGUGAUU G UGGAAUUC
8902
GAAUUCCA GCCGAAAGGCGAGUGAGGUCU AAUCACCA
20525





3059
CGAAUUCU G CAAAUUUG
8904
CAAAUUUG GCCGAAAGCCGAGUGAGGUCU AGAAUUCC
20526





3075
GGAAACCU G UCCACUUA
8907
UAAGUCGA GCCGAAAGCCGACUGAGGUCU AGGUUUCC
20527





3092
CCUGAGGA G CAACAGAA
8908
UUCUCUUG GCCGAAAGGCGAGUGAGGUCU UCCUCAGG
20528





3109
AUGAAUUU G UCCCCUAC
8911
GUAGGGGA GCCGAAAGGCGAGUGAGGUCU AAAUUCAU
20529





3130
CCAAAGGG G CACGAUUC
8913
GAAUCGUG GCCGAAAGGCCAGUGAGGUCU CCCUUUCG
20530





3140
ACGAUUCC G UCAAGGGA
8915
UCCCUUCA GCCGAAAGGCGAGUGAGGUCU GGAAUCGU
20531





3157
AAGACUAC G UUGGAGCA
8917
UGCUCCAA GCCGAAAGGCGAGUGAGGUCU GUAGUCUU
20532





3163
ACGUUGGA G CAAUCCCU
8918
AGGGAUUG GCCGAAAGGCGAGUGAGCUCU UCCAACGU
20533





3172
CAAUCCCU G UGGAUCUG
8920
CAGAUCCA GCCGAAAGGCGACUGAGGUCU AGGGAUUG
20534





3186
CUGAAACG G CGCUUGGA
8923
UCCAACCG GCCGAAAGGCGAGUGAGGUCU CGUUUCAG
20535





3188
CAAACGGC G CUUCCACA
8924
UGUCCAAG GCCGAAAGGCGAGUGAGGUCU GCCGUUUC
20536





3197
CUUGGACA G CAUCACCA
8926
UCCUGAUG GCCGAAAGGCGAGUGAGGUCU UGUCCAAG
20537





3206
CAUCACCA G UAGCCACA
8927
UCUGGCUA GCCGAAACGCGAGUGAGGUCU UGCUGAUG
20538





3209
CACCAGUA G CCACAGCU
8928
AGCUCUGG CCCGAAAGGCGAGUGAGGUCU UACUGGUG
20539





3215
UAGCCAGA G CUCAGCCA
8929
UGGCUCAG GCCGAAAGGCGACUGAGGUCU UCUGGCUA
20540





3220
AGACCUCA G CCACCUCU
8930
AGAGCUGG GCCGAAAGGCGAGUGAGGUCU UCAGCUCU
20541





3224
CUCAGCCA G CUCUCCAU
8931
AUCCAGAG GCCGAAACGCCAGUGAGGUCU UGGCUGAG
20542





3235
CUGGAUUU G UGGAGGAG
8933
CUCCUCCA GCCGAAAGGCGAGUGAGCUCU AAAUCCAC
20543





3246
GAGGAGAA G UCCCUCAG
8934
CUGAGGGA CCCGAAAGGCGAGUGAGGUCU UUCUCCUC
20544





3254
GUCCCUCA G UGAUGUAG
8935
CUACAUCA GCCGAAAGGCGAGUGAGGUCU UGAGGGAC
20545





3259
UCACUGAU G UAGAAGAA
8937
UUCUUCUA CCCCAAAGGCCACUGAGGUCU AUCACUGA
20546





3274
AAGAGGAA G CUCCUGAA
8938
UUCAGCAG GCCGAAAGGCGACUGAGGUCU UUCCUCUU
20547





3288
GAAGAUCU G UAUAAGGA
8940
UCCUUAUA CCCCAAAGGCCAGUGAGCUCU AGAUCUUC
20548





3312
ACCUUGCA G CAUCUCAU
8943
AUGAGAUG GCCGAAAGGCGAGUCAGGUCU UCCAAGCU
20549





3323
UCUCAUCU G UUACAGCU
8944
AGCUGUAA GCCGAAAGGCGACUCAGGUCU AGAUCACA
20550





3329
CUGUUACA G CUUCCAAC
8945
CUUGGAAG GCCCAAACCCCAGUGACCUCU UCUAACAG
20551





3337
GCUUCCAA G UGGCUAAG
8946
CUUAGCCA CCCCAAACGCCACUGACGUCU UUCGAAGC
20552





3340
UCCAAGUC G CUAAGCGC
8947
CCCCUUAG GCCCAAAGGCGACUGAGGUCU CACUUGCA
20553





3347
CGCUAAGG G CAUGGAGU
8948
ACUCCAUC GCCCAAACCCCACUCACGUCU CCUUACCC
20554





3354
GCCAUCCA G UUCUUCGC
8949
CCCAACAA CCCCAAACGCGAGUGAGGUCU UCCAUCCC
20555





3361
AGUUCUUC G CAUCCCCA
8950
UCGCCAUC CCCCAAAGGCGAGUGAGGUCU CAACAACU
20556





3366
UUGGCAUC G CGAAAGUC
8951
CACUUUCC GCCCAAAGCCGAGUCACCUCU CAUCCCAA
20557





3372
UCCCCAAA G UCUAUCCA
8952
UCCAUACA CCCCAAAGCCCACUCACGUCU UUUCCCCA
20558





3374
GCGAAAGU G UAUCCACA
8953
UGUCCAUA CCCCAAACGCGAGUCACCUCU ACUUUCGC
20559





3391
CGGACCUC G CGCCACCA
8955
UCCUCCCC GCCGAAAGCCGAGUCAGCUCU CACGUCCC
20560





3394
ACCUCCCC G CACCAAAU
8956
AUUUCCUG CCCCAAACCCGAGUGACCUCU CGCCAGCU
20561





3424
AGAACAAC G UGGUUAAA
8959
UUUAACCA GCCGAAAGGCCAGUGACGUCU CUUCUUCU
20562





3427
ACAACCUG G UUAAAAUC
8960
CAUUUUAA CCCCAAACGCCAGUGACGUCU CACCUUCU
20563





3437
UAAAAUCU G UGACUUUC
8962
CAAAGUCA GCCGAAAGGCGAGUGAGGUCU ACAUUUUA
20564





3446
UCACUCUC G CUUGCCCC
8964
CCGCCAAC CCCCAAACCCCACUCACCUCU CAAACUCA
20565





3451
UUCGCUUG G CCCCCGAU
8965
AUCCCCCC GCCGAAAGGCGACUGAGGUCU CAAGCCAA
20566





3481
CAGAUUAU G UCAGAAAA
8969
UUUUCUGA GCCGAAAGGCGAGUGAGGUCU AUAAUCUG
20567





3496
AAGGAGAU G CUCGCCUC
8971
GAGGCGAG GCCGAAAGGCGAGUGAGGUCU AUCUCCUU
20568





3500
AGAUGCUC G CCUCCCUU
8972
AAGGGAGG GCCGAAAGGCGAGUGAGGUCU GAGCAUCU
20569





3520
AAUGGAUG G CCCCAGAA
8975
UUCUGGGG GCCGAAAGGCGAGUGAGGUCU CAUCCAUU
20570





3544
UUGACAGA G UGUACACA
8979
UGUGUACA GCCGAAAGGCGAGUGAGGUCU UCUGUCAA
20571





3546
GACAGAGU G UACACAAU
8980
AUUGUGUA GCCGAAAGGCGAGUGAGGUCU ACUCUGUC
20572





3560
AAUCCAGA G UGACGUCU
8982
AGACGUCA GCCGAAAGGCGAGUGAGGUCU UCUGGAUU
20573





3565
AGAGUGAC G UCUGGUCU
8984
AGACCAGA GCCGAAAGGCGAGUGAGGUCU GUCACUCU
20574





3570
GACGUCUG G UCUUUUGG
8985
CCAAAAGA GCCGAAAGGCGAGUGAGGUCU CAGACGUC
20575





3578
GUCUUUUG G UGUUUUGC
8986
GCAAAACA GCCGAAAGGCGAGUGAGGUCU CAAAAGAC
20576





3580
CUUUUGGU G UUUUGCUG
8987
CAGCAAAA GCCGAAAGGCGAGUGAGGUCU ACCAAAAG
20577





3585
GGUGUUUU G CUGUGGGA
8988
UCCCACAG GCCGAAAGGCGAGUGAGGUCU AAAACACC
20578





3588
GUUUUGCU G UGGGAAAU
8989
AUUUCCCA GCCGAAAGGCGAGUGAGGUCU AGCAAAAC
20579





3608
UUCCUUAG G UGCUUCUC
8991
GAGAAGCA GCCGAAAGGCGAGUGAGGUCU CUAAGGAA
20580





3610
CCUUAGGU G CUUCUCCA
8992
UGGAGAAG GCCGAAAGGCGAGUGAGGUCU ACCUAAGG
20581





3628
AUCCUGGG G UAAAGAUU
8993
AAUCUUUA GCCGAAAGGCGAGUGAGGUCU CCCAGGAU
20582





3650
AGAAUUUU G UAGGCGAU
8997
AUCGCCUA GCCGAAAGGCGAGUGAGGUCU AAAAUUCU
20583





3654
UUUUGUAG G CGAUUGAA
8998
UUCAAUCG GCCGAAAGGCGAGUGAGGUCU CUACAAAA
20584





3682
GAAUGAGG G CCCCUGAU
9002
AUCAGGGG GCCGAAAGGCGAGUGAGGUCU CCUCAUUC
20585





3708
CCAGAAAU G UACCAGAC
9005
GUCUGGUA GCCGAAAGGCGAGUGAGGUCU AUUUCUGG
20586





3720
CAGACCAU G CUGGACUG
9007
CAGUCCAG GCCGAAAGGCGAGUGAGGUCU AUGGUCUG
20587





3728
GCUGGACU G CUGGCACG
9008
CGUGCCAG GCCGAAAGGCGAGUGAGGUCU AGUCCAGC
20588





3732
GACUGCUG G CACGGGGA
9009
UCCCCGUG GCCGAAAGGCGAGUGAGGUCU CAGCAGUC
20589





3741
CACGGGGA G CCCAGUCA
9010
UGACUGGG GCCGAAAGGCGAGUGAGGUCU UCCCCGUG
20590





3746
GGAGCCCA G UCAGAGAC
9011
GUCUCUGA GCCGAAAGGCGAGUGAGGUCU UGGGCUCC
20591





3759
AGACCCAC G UUUUCAGA
9013
UCUGAAAA GCCGAAAGGCGAGUGAGGUCU GUGGGUCU
20592





3768
UUUUCAGA G UUGGUGGA
9014
UCCACCAA GCCGAAAGGCGAGUGAGGUCU UCUGAAAA
20593





3772
CAGAGUUG G UGGAACAU
9015
AUGUUCCA GCCGAAAGGCGAGUGAGGUCU CAACUCUG
20594





3795
AAUCUCUU G CAAGCUAA
9018
UUAGCUUG GCCGAAAGGCGAGUGAGGUCU AAGAGAUU
20595





3799
UCUUGCAA G CUAAUGCU
9019
AGCAUUAG GCCGAAAGGCGAGUGAGGUCU UUGCAAGA
20596





3805
AAGCUAAU G CUCAGCAG
9021
CUGCUGAG GCCGAAAGGCGAGUGAGGUCU AUUAGCUU
20597





3810
AAUGCUCA G CAGGAUGG
9022
CCAUCCUG GCCGAAAGGCGAGUGAGGUCU UGAGCAUU
20598





3818
GCAGGAUG G CAAAGACU
9024
AGUCUUUG GCCGAAAGGCGAGUGAGGUCU CAUCCUGC
20599





3832
ACUACAUU G UUCUUCCG
9026
CGGAAGAA GCCGAAAGGCGAGUGAGGUCU AAUGUAGU
20600





3857
GACUUUGA G CAUGGAAG
9029
CUUCCAUG GCCGAAAGGCGAGUGAGGUCU UCAAAGUC
20601





3885
CUCUCUCU G CCUACCUC
9032
GAGGUAGG GCCGAAAGGCGAGUGAGGUCU AGAGAGAG
20602





3898
CCUCACCU G UUUCCUGU
9033
ACAGGAAA GCCGAAAGGCGAGUGAGGUCU AGGUGAGG
20603





3905
UGUUUCCU G UAUGGAGG
9034
CCUCCAUA GCCGAAAGGCGAGUGAGGUCU AGGAAACA
20604





3922
AGGAGGAA G UAUGUGAC
9035
GUCACAUA GCCGAAAGGCGAGUGAGGUCU UUCCUCCU
20605





3926
GGAAGUAU G UGACCCCA
9036
UGGGGUCA GCCGAAAGGCGAGUGAGGUCU AUACUUCC
20606





3955
ACAACACA G CAGGAAUC
9041
GAUUCCUG GCCGAAAGGCGAGUGAGGUCU UGUGUUGU
20607





3965
AGGAAUCA G UCAGUAUC
9043
GAUACUGA GCCGAAAGGCGAGUGAGGUCU UGAUUCCU
20608





3969
AUCAGUCA G UAUCUGCA
9044
UGCAGAUA GCCGAAAGGCGAGUGAGGUCU UGACUGAU
20609





3975
CAGUAUCU G CAGAACAG
9045
CUGUUCUG GCCGAAAGGCGAGUGAGGUCU AGAUACUG
20610





3983
GCAGAACA G UAAGCGAA
9047
UUCGCUUA GCCGAAAGGCGAGUGAGGUCU UGUUCUGC
20611





3987
AACAGUAA G CGAAAGAG
9048
CUCUUUCG GCCGAAAGGCGAGUGAGGUCU UUACUGUU
20612





3995
GCGAAAGA G CCGGCCUG
9049
CAGGCCGG GCCGAAAGGCGAGUGAGGUCU UCUUUCGC
20613





3999
AAGAGCCG G CCUGUGAG
9050
CUCACAGG GCCGAAAGGCGAGUGAGGUCU CGGCUCUU
20614





4003
GCCGGCCU G UGAGUGUA
9051
UACACUCA GCCGAAAGGCGAGUGAGGUCU AGGCCGGC
20615





4007
GCCUGUGA G UGUAAAAA
9052
UUUUUACA GCCGAAAGGCGAGUGAGGUCU UCACAGGC
20616





4009
CUGUGAGU G UAAAAACA
9053
UGUUUUUA GCCGAAAGGCGAGUGAGGUCU ACUCACAG
20617





4032
GAUAUCCC G UUAGAAGA
9056
UCUUCUAA GCCGAAAGGCGAGUGAGGUCU GGGAUAUC
20618





4048
AACCAGAA G UAAAAGUA
9058
UACUUUUA GCCGAAAGGCGAGUGAGGUCU UUCUGGUU
20619





4054
AAGUAAAA G UAAUCCCA
9059
UGGGAUUA GCCGAAAGGCGAGUGAGGUCU UUUUACUU
20620





4082
GACGGACA G UGGUAUGG
9066
CCAUACCA GCCGAAAGGCGAGUGAGGUCU UGUCCGUC
20621





4085
GGACAGUG G UAUGGUUC
9067
GAACCAUA GCCGAAAGGCGAGUGAGGUCU CACUGUCC
20622





4090
GUGGUAUG G UUCUUGCC
9068
GGCAAGAA GCCGAAAGGCGAGUGAGGUCU CAUACCAC
20623





4096
UGGUUCUU G CCUCAGAA
9069
UUCUGAGG GCCGAAAGGCGAGUGAGGUCU AAGAACCA
20624





4107
UCAGAAGA G CUGAAAAC
9070
GUUUUCAG GCCGAAAGGCGAGUGAGGUCU UCUUCUGA
20625





4151
AUCUUUUG G UGGAAUGG
9075
CCAUUCCA GCCGAAAGGCGAGUGAGGUCU CAAAAGAU
20626





4159
GUGGAAUG G UGCCCAGC
9077
GCUGGGCA GCCGAAAGGCGAGUGAGGUCU CAUUCCAC
20627





4161
GGAAUGGU G CCCAGCAA
9078
UUGCUGGG GCCGAAAGGCGAGUGAGGUCU ACCAUUCC
20628





4166
GGUGCCCA G CAAAAGCA
9079
UGCUUUUG GCCGAAAGGCGAGUGAGGUCU UGGGCACC
20629





4172
CAGCAAAA G CAGGGAGU
9080
ACUCCCUG GCCGAAAGGCGAGUGAGGUCU UUUUGCUG
20630





4179
AGCAGGGA G UCUGUGGC
9081
GCCACAGA GCCGAAAGGCGAGUGAGGUCU UCCCUGCU
20631





4183
GGGAGUCU G UGGCAUCU
9082
AGAUGCCA GCCGAAAGGCGAGUGAGGUCU AGACUCCC
20632





4186
AGUCUGUG G CAUCUGAA
9083
UUCAGAUG GCCGAAAGGCGAGUGAGGUCU CACAGACU
20633





4196
AUCUGAAG G CUCAAACC
9084
GGUUUGAG GCCGAAAGGCGAGUGAGGUCU CUUCAGAU
20634





4211
CCAGACAA G CGGCUACC
9087
GGUAGCCG GCCGAAAGGCGAGUGAGGUCU UUGUCUGG
20635





4214
GACAAGCG G CUACCAGU
9088
ACUGGUAG GCCGAAAGGCGAGUGAGGUCU CGCUUGUC
20636





4221
GGCUACCA G UCCGGAUA
9089
UAUCCGGA GCCGAAAGGCGAGUGAGGUCU UGGUAGCC
20637





4255
ACACCACC G UGUACUCC
9094
GGAGUACA GCCGAAAGGCGAGUGAGGUCU GGUGGUGU
20638





4257
ACCACCGU G UACUCCAG
9095
CUGGAGUA GCCGAAAGGCGAGUGAGGUCU ACGGUGGU
20639





4265
GUACUCCA G UGAGGAAG
9096
CUUCCUCA GCCGAAAGGCGAGUGAGGUCU UGGAGUAC
20640





4273
GUGAGGAA G CAGAACUU
9097
AAGUUCUG GCCGAAAGGCGAGUGAGGUCU UUCCUCAC
20641





4287
CUUUUAAA G CUGAUAGA
9099
UCUAUCAG GCCGAAAGGCGAGUGAGGUCU UUUAAAAG
20642





4303
AGAUUGGA G UGCAAACC
9102
GGUUUGCA GCCGAAAGGCGAGUGAGGUCU UCCAAUCU
20643





4305
AUUGGAGU G CAAACCGG
9103
CCGGUUUG GCCGAAAGGCGAGUGAGGUCU ACUCCAAU
20644





4313
GCAAACCG G UAGCACAG
9105
CUGUGCUA GCCGAAAGGCGAGUGAGGUCU CGGUUUGC
20645





4316
AACCGGUA G CACAGCCC
9106
GGGCUGUG GCCGAAAGGCGAGUGAGGUCU UACCGGUU
20646





4321
GUAGCACA G CCCAGAUU
9107
AAUCUGGG GCCGAAAGGCGAGUGAGGUCU UGUGCUAC
20647





4335
AUUCUCCA G CCUGACUC
9109
GAGUCAGG GCCGAAAGGCGAGUGAGGUCU UGGAGAAU
20648





4358
CACACUGA G CUCUCCUC
9112
GAGGAGAG GCCGAAAGGCGAGUGAGGUCU UCAGUGUG
20649





4369
CUCCUCCU G UUUAAAAG
9113
CUUUUAAA GCCGAAAGGCGAGUGAGGUCU AGGAGGAG
20650





4381
AAAAGGAA G CAUCCACA
9114
UGUGGAUG GCCGAAAGGCGAGUGAGGUCU UUCCUUUU
20651





4417
CAUGAGAG G UCUGCUCA
9117
UGAGCAGA GCCGAAAGGCGAGUGAGGUCU CUCUCAUG
20652





4421
AGAGGUCU G CUCAGAUU
9118
AAUCUGAG GCCGAAAGGCGAGUGAGGUCU AGACCUCU
20653





4435
AUUUUGAA G UGUUGUUC
9120
GAACAACA GCCGAAAGGCGAGUGAGGUCU UUCAAAAU
20654





4437
UUUGAAGU G UUGUUCUU
9121
AAGAACAA GCCGAAAGGCGAGUGAGGUCU ACUUCAAA
20655





4440
GAAGUGUU G UUCUUUCC
9122
GGAAAGAA GCCGAAAGGCGAGUGAGGUCU AACACUUC
20656





4453
UUCCACCA G CAGGAAGU
9123
ACUUCCUG GCCGAAAGGCGAGUGAGGUCU UGGUGGAA
20657





4460
AGCAGGAA G UAGCCGCA
9124
UGCGGCUA GCCGAAAGGCGAGUGAGGUCU UUCCUGCU
20658





4463
AGGAAGUA G CCGCAUUU
9125
AAAUGCGG GCCGAAAGGCGAGUGAGGUCU UACUUCCU
20659





4466
AAGUAGCC G CAUUUGAU
9126
AUCAAAUG GCCGAAAGGCGAGUGAGGUCU GGCUACUU
20660





4509
CUCGGACU G CAGGGAGC
9132
GCUCCCUG GCCGAAAGGCGAGUGAGGUCU AGUCCGAG
20661





4516
UGCAGGGA G CCAGUCUU
9133
AAGACUGG GCCGAAAGGCGAGUGAGGUCU UCCCUGCA
20662





4520
GGGAGCCA G UCUUCUAG
9134
CUAGAAGA GCCGAAAGGCGAGUGAGGUCU UGGCUCCC
20663





4529
UCUUCUAG G CAUAUCCU
9135
AGGAUAUG GCCGAAAGGCGAGUGAGGUCU CUAGAAGA
20664





4545
UGGAAGAG G CUUGUGAC
9138
GUCACAAG GCCGAAAGGCGAGUGAGGUCU CUCUUCCA
20665





4549
AGAGGCUU G UGACCCAA
9139
UUGGGUCA GCCGAAAGGCGAGUGAGGUCU AAGCCUCU
20666





4562
CCAAGAAU G UGUCUGUG
9142
CACAGACA GCCGAAAGGCGAGUGAGGUCU AUUCUUGG
20667





4564
AAGAAUGU G UCUGUGUC
9143
GACACAGA GCCGAAAGGCGAGUGAGGUCU ACAUUCUU
20668





4566
AUGUGUCU G UGUCUUCU
9144
AGAAGACA GCCGAAAGGCGAGUGAGGUCU AGACACAU
20669





4570
GUGUCUGU G UCUUCUCC
9145
GGAGAAGA GCCGAAAGGCGAGUGAGGUCU ACAGACAC
20670





4581
UUCUCCCA G UGUUGACC
9146
GGUCAACA GCCGAAAGGCGAGUGAGGUCU UGGGAGAA
20671





4583
CUCCCAGU G UUGACCUG
9147
CAGGUCAA GCCGAAAGGCGAGUGAGGUCU ACUGGGAG
20672





4618
UUUAAAAA G CAUUAUCA
9152
UGAUAAUG GCCGAAAGGCGAGUGAGGUCU UUUUUAAA
20673





4628
AUUAUCAU G CCCCUGCU
9156
AGCAGGGG GCCGAAAGGCGAGUGAGGUCU AUGAUAAU
20674





4634
AUGCCCCU G CUGCGGGU
9157
ACCCGCAG GCCGAAAGGCGAGUGAGGUCU AGGGGCAU
20675





4637
CCCCUGCU G CGGGUCUC
9158
GAGACCCG GCCGAAAGGCGAGUGAGGUCU AGCAGGGG
20676





4641
UGCUGCGG G UCUCACCA
9159
UGGUGAGA GCCGAAAGGCGAGUGAGGUCU CCGCAGCA
20677





4653
CACCAUGG G UUUAGAAC
9162
GUUCUAAA GCCGAAAGGCGAGUGAGGUCU CCAUGGUG
20678





4667
AACAAAGA G CUUCAAGC
9164
GCUUGAAG GCCGAAAGGCGAGUGAGGUCU UCUUUGUU
20679





4674
AGCUUCAA G CAAUGGCC
9165
GGCCAUUG GCCGAAAGGCGAGUGAGGUCU UUGAAGCU
20680





4680
AAGCAAUG G CCCCAUCC
9167
GGAUGGGG GCCGAAAGGCGAGUGAGGUCU CAUUGCUU
20681





4697
UCAAAGAA G UAGCAGUA
9169
UACUGCUA GCCGAAAGGCGAGUGAGGUCU UUCUUUGA
20682





4700
AAGAAGUA G CAGUACCU
9170
AGGUACUG GCCGAAAGGCGAGUGAGGUCU UACUUCUU
20683





4703
AAGUAGCA G UACCUGGG
9171
CCCAGGUA GCCGAAAGGCGAGUGAGGUCU UGCUACUU
20684





4714
CCUGGGGA G CUGACACU
9173
AGUGUCAG GCCGAAAGGCGAGUGAGGUCU UCCCCAGG
20685





4726
ACACUUCU G UAAAACUA
9176
UAGUUUUA GCCGAAAGGCGAGUGAGGUCU AGAAGUGU
20686





4748
UAAACCAG G CAACGUAA
9180
UUACGUUG GCCGAAAGGCGAGUGAGGUCU CUGGUUUA
20687





4753
CAGGCAAC G UAAGUGUU
9182
AACACUUA GCCGAAAGGCGAGUGAGGUCU GUUGCCUG
20688





4757
CAACGUAA G UGUUCGAG
9183
CUCGAACA GCCGAAAGGCGAGUGAGGUCU UUACGUUG
20689





4759
ACGUAAGU G UUCGAGGU
9184
ACCUCGAA GCCGAAAGGCGAGUGAGGUCU ACUUACGU
20690





4766
UGUUCGAG G UGUUGAAG
9185
CUUCAACA GCCGAAAGGCGAGUGAGGUCU CUCGAACA
20691





4768
UUCGAGGU G UUGAAGAU
9186
AUCUUCAA GCCGAAAGGCGAGUGAGGUCU ACCUCGAA
20692





4788
AAGGAUUU G CAGGGCUG
9189
CAGCCCUG GCCGAAAGGCGAGUGAGGUCU AAAUCCUU
20693





4793
UUUGCAGG G CUGAGUCU
9190
AGACUCAG GCCGAAAGGCGAGUGAGGUCU CCUGCAAA
20694





4798
AGGGCUGA G UCUAUCCA
9191
UGGAUAGA GCCGAAAGGCGAGUGAGGUCU UCAGCCCU
20695





4811
UCCAAGAG G CUUUGUUU
9193
AAACAAAG GCCGAAAGGCGAGUGAGGUCU CUCUUGGA
20696





4816
GAGGCUUU G UUUAGGAC
9194
GUCCUAAA GCCGAAAGGCGAGUGAGGUCU AAAGCCUC
20697





4825
UUEUGGAC G UGGGUCCC
9196
GGGACCCA GCCGAAAGGCGAGUGAGGUCU GUCCUAAA
20698





4829
GGACGUGG G UCCCAAGC
9197
GCUUGGGA GCCGAAAGGCGAGUGAGGUCU CCACGUCC
20699





4836
GGUCCCAA G CCAAGCCU
9198
AGGCUUGG GCCGAAAGGCGAGUGAGGUCU UUGGGACC
20700





4841
CAAGCCAA G CCUUAAGU
9199
ACUUAAGG GCCGAAAGGCGAGUGAGGUCU UUGGCUUG
20701





4848
AGCCUUAA G UGUGGAAU
9200
AUUCCACA GCCGAAAGGCGAGUGAGGUCU UUAAGGCU
20702





4850
CCUUAAGU G UGGAAUUC
9201
GAAUUCCA GCCGAAAGGCGAGUGAGGUCU ACUUAAGG
20703





4883
AGACUAAC G UUACCUUG
9207
CAAGGUAA GCCGAAAGGCGAGUGAGGUCU GUUAGUCU
20704





4891
GUUACCUU G CUUUGGAG
9209
CUCCAAAG GCCGAAAGGCGAGUGAGGUCU AAGGUAAC
20705





4901
UUUGGAGA G UACUGGAG
9210
CUCCAGUA GCCGAAAGGCGAGUGAGGUCU UCUCCAAA
20706





4909
GUACUGGA G CCUGCAAA
9212
UUUGCAGG GCCGAAAGGCGAGUGAGGUCU UCCAGUAC
20707





4913
UGGAGCCU G CAAAUGCA
9213
UGCAUUUG GCCGAAAGGCGAGUGAGGUCU AGGCUCCA
20708





4919
CUGCAAAU G CAUUGUGU
9215
ACACAAUG GCCGAAAGGCGAGUGAGGUCU AUUUGCAG
20709





4924
AAUGCAUU G UGUUUGCU
9217
AGCAAACA GCCGAAAGGCGAGUGAGGUCU AAUGCAUU
20710





4926
UGCAUUGU G UUUGCUCU
9218
AGAGCAAA GCCGAAAGGCGAGUGAGGUCU ACAAUGCA
20711





4930
UUGUGUUU G CUCUGGUG
9219
CACCAGAG GCCGAAAGGCGAGUGAGGUCU AAACACAA
20712





4936
UUGCUCUG G UGGAGGUG
9220
CACCUCCA GCCGAAAGGCGAGUGAGGUCU CAGAGCAA
20713





4942
UGGUGGAG G UGGGCAUG
9221
CAUGCCCA GCCGAAAGGCGAGUGAGGUCU CUCCACCA
20714





4946
GGAGGUGG G CAUGGGGU
9222
ACCCCAUG GCCGAAAGGCGAGUGAGGUCU CCACCUCC
20715





4953
GGCAUGGG G UCUGUUCU
9224
AGAACAGA GCCGAAAGGCGAGUGAGGUCU CCCAUGCC
20716





4957
UGGGGUCU G UUCUGAAA
9225
UUUCAGAA GCCGAAAGGCGAGUGAGGUCU AGACCCCA
20717





4967
UCUGAAAU G UAAAGGGU
9227
ACCCUUUA GCCGAAAGGCGAGUGAGGUCU AUUUCAGA
20718





4974
UGUAAAGG G UUCAGACG
9228
CGUCUGAA GCCGAAAGGCGAGUGAGGUCU CCUUUACA
20719





4985
CAGACGGG G UUUCUGGU
9230
ACCAGAAA GCCGAAAGGCGAGUGAGGUCU CCCGUCUG
20720





4992
GGUUUCUG G UUUUAGAA
9231
UUCUAAAA GCCGAAAGGCGAGUGAGGUCU CAGAAACC
20721





5002
UUUAGAAG G UUGCGUGU
9232
ACACGCAA GCCGAAAGGCGAGUGAGGUCU CUUCUAAA
20722





5005
AGAAGGUU G CGUGUUCU
9233
AGAACACG GCCGAAAGGCGAGUGAGGUCU AACCUUCU
20723





5007
AAGGUUGC G UGUUCUUC
9234
GAAGAACA GCCGAAAGGCGAGUGAGGUCU GCAACCUU
20724





5009
GGUUGCGU G UUCUUCGA
9235
UCGAAGAA GCCGAAAGGCGAGUGAGGUCU ACGCAACC
20725





5018
UUCUUCGA G UUGGGCUA
9236
UACCCCAA GCCGAAAGGCGAGUGAGGUCU UCGAAGAA
20726





5023
CGAGUUGG G CUAAAGUA
9237
UACUUUAG GCCGAAAGGCGAGUGAGGUCU CCAACUCG
20727





5029
GGGCUAAA G UAGAGUUC
9238
GAACUCUA GCCGAAAGGCGAGUGAGGUCU UUUAGCCC
20728





5034
AAAGUAGA G UUCGUUGU
9239
ACAACGAA GCCGAAAGGCGAGUGAGGUCU UCUACUUU
20729





5038
UAGAGUUC G UUGUGCUG
9240
CAGCACAA GCCGAAAGGCGAGUGAGGUCU GAACUCUA
20730





5041
AGUUCGUU G UGCUGUUU
9241
AAACAGCA GCCGAAAGGCGAGUGAGGUCU AACGAACU
20731





5043
UUCGUUGU G CUGUUUCU
9242
AGAAACAG GCCGAAAGGCGAGUGAGGUCU ACAACGAA
20732





5046
GUUGUGCU G UUUCUGAC
9243
GUCAGAAA GCCGAAAGGCGAGUGAGGUCU AGCACAAC
20733





5066
UAAUGAGA G UUCCUUCC
9246
GGAAGGAA GCCGAAAGGCGAGUGAGGUCU UCUCAUUA
20734





5080
UCCAGACC G UUAGCUGU
9248
ACAGCUAA GCCGAAAGGCGAGUGAGGUCU GGUCUGGA
20735





5084
GACCGUUA G CUGUCUCC
9249
GGAGACAG GCCGAAAGGCGAGUGAGGUCU UAACGGUC
20736





5087
CGUUAGCU G UCUCCUUG
9250
CAAGGAGA GCCGAAAGGCGAGUGAGGUCU AGCUAACG
20737





5095
GUCUCCUU G CCAAGCCC
9251
GGGCUUGG GCCGAAAGGCGAGUGAGGUCU AAGGAGAC
20738





5100
CUUGCCAA G CCCCAGGA
9252
UCCUGGGG GCCGAAAGGCGAGUGAGGUCU UUGGCAAG
20739





5119
AAAAUGAU G CAGCUCUG
9255
CAGAGCUG GCCGAAAGGCGAGUGAGGUCU AUCAUUUU
20740





5122
AUGAUGCA G CUCUGGCU
9256
AGCCAGAG GCCGAAAGGCGAGUGAGGUCU UGCAUCAU
20741





5128
CAGCUCUG G CUCCUUGU
9257
ACAAGGAG GCCGAAAGGCGAGUGAGGUCU CAGAGCUG
20742





5135
GGCUCCUU G UCUCCCAG
9258
CUGGGAGA GCCGAAAGGCGAGUGAGGUCU AAGGAGCC
20743





5144
UCUCCCAG G CUGAUCCU
9259
AGGAUCAG GCCGAAAGGCGAGUGAGGUCU CUGGGAGA
20744





5185
GACAUUCA G CUCAAGGC
9267
GCCUUGAG GCCGAAAGGCGAGUGAGGUCU UGAAUGUC
20745





5192
AGCUCAAG G CUCCCUGC
9268
GCAGGGAG GCCGAAAGGCGAGUGAGGUCU CUUGAGCU
20746





5199
GGCUCCCU G CCGUGUUG
9269
CAACACGG GCCGAAAGGCGAGUGAGGUCU AGGGAGCC
20747





5202
UCCCUGCC G UGUUGAAG
9270
CUUCAACA GCCGAAAGGCGAGUGAGGUCU GGCAGGGA
20748





5204
CCUGCCGU G UUGAAGAG
9271
CUCUUCAA GCCGAAAGGCGAGUGAGGUCU ACGGCAGG
20749





5212
GUUGAAGA G UUCUGACU
9272
AGUCAGAA GCCGAAAGGCGAGUGAGGUCU UCUUCAAC
20750





5221
UUCUGACU G CACAAACC
9274
GGUUUGUG GCCGAAAGGCGAGUGAGGUCU AGUCAGAA
20751





5231
ACAAACCA G CUUCUGGU
9277
ACCAGAAG GCCGAAAGGCGAGUGAGGUCU UGGUUUGU
20752





5238
AGCUUCUG G UUUCUUCU
9278
AGAAGAAA GCCGAAAGGCGAGUGAGGUCU CAGAAGCU
20753





5268
UCAUAUCU G UCCUGAUG
9284
CAUCAGGA GCCGAAAGGCGAGUGAGGUCU AGAUAUGA
20754





5276
GUCCUGAU G UGAUAUGU
9286
ACAUAUCA GCCGAAAGGCGAGUGAGGUCU AUCAGGAC
20755





5283
UGUGAUAU G UCUGAGAC
9289
GUCUCAGA GCCGAAAGGCGAGUGAGGUCU AUAUCACA
20756





5297
GACUGAAU G CGGGAGGU
9292
ACCUCCCG GCCGAAAGGCGAGUGAGGUCU AUUCAGUC
20757





5304
UGCGGGAG G UUCAAUGU
9293
ACAUUGAA GCCGAAAGGCGAGUGAGGUCU CUCCCGCA
20758





5311
GGUUCAAU G UGAAGCUG
9295
CAGCUUCA GCCGAAAGGCGAGUGAGGUCU AUUGAACC
20759





5316
AAUGUGAA G CUGUGUGU
9296
ACACACAG GCCGAAAGGCGAGUGAGGUCU UUCACAUU
20760





5319
GUGAAGCU G UGUGUGGU
9297
ACCACACA GCCGAAAGGCGAGUGAGGUCU AGCUUCAC
20761





5321
GAAGCUGU G UGUGGUGU
9298
ACACCACA GCCGAAAGGCGAGUGAGGUCU ACAGCUUC
20762





5323
AGCUGUGU G UGGUGUCA
9299
UGACACCA GCCGAAAGGCGAGUGAGGUCU ACACAGCU
20763





5326
UGUGUGUG G UGUCAAAG
9300
CUUUGACA GCCGAAAGGCGAGUGAGGUCU CACACACA
20764





5329
UGUGUGGU G UCAAAGUU
9301
AACUUUGA GCCGAAAGGCGAGUGAGGUCU ACCACACA
20765





5334
GUGUCAAA G UUUCAGGA
9302
UCCUGAAA GCCGAAAGGCGAGUGAGGUCU UUUGACAC
20766





5359
ACCCUUUU G UUCUUCCC
9305
GGGAAGAA GCCGAAAGGCGAGUGAGGUCU AAAAGGGU
20767





5371
UUCCCCCU G UCCCCAAC
9306
GUUGGGGA GCCGAAAGGCGAGUGAGGUCU AGGGGGAA
20768





5393
CUCACCCC G CAACCCAU
9310
AUGGGUUG GCCGAAAGGCGAGUGAGGUCU GGGGUGAG
20769





5404
ACCCAUCA G UAUUUUAG
9313
CUAAAAUA GCCGAAAGGCGAGUGAGGUCU UGAUGGGU
20770





5412
GUAUUUUA G UUAUUUGG
9315
CCAAAUAA GCCGAAAGGCGAGUGAGGUCU UAAAAUAC
20771





5420
GUUAUUUG G CCUCUACU
9317
AGUAGAGG GCCGAAAGGCGAGUGAGGUCU CAAAUAAC
20772





5432
CUACUCCA G UAAACCUG
9319
CAGGUUUA GCCGAAAGGCGAGUGAGGUCU UGGAGUAG
20773





5446
CUGAUUGG G UUUGUUCA
9322
UGAACAAA GCCGAAAGGCGAGUGAGGUCU CCAAUCAG
20774





5450
UUGGGUUU G UUCACUCU
9323
AGAGUGAA GCCGAAAGGCGAGUGAGGUCU AAACCCAA
20775





5473
GAUUAUUA G CCAGACUU
9326
AAGUCUGG GCCGAAAGGCGAGUGAGGUCU UAAUAAUC
20776





5497
AUUUUAUA G CCCAAAUU
9333
AAUUUGGG GCCGAAAGGCGAGUGAGGUCU UAUAAAAU
20777





5518
CAUCUAUU G UAUUAUUU
9339
AAAUAAUA GCCGAAAGGCGAGUGAGGUCU AAUAGAUG
20778





5545
CAUAUAGA G CUAUUUCU
9346
AGAAAUAG GCCGAAAGGCGAGUGAGGUCU UCUAUAUG
20779





5564
UGAUUUUU G CCCUUGUU
9350
AACAAGGG GCCGAAAGGCGAGUGAGGUCU AAAAAUCA
20780





5570
UUGCCCUU G UUCUGUCC
9351
GGACAGAA GCCGAAAGGCGAGUGAGGUCU AAGGGCAA
20781





5575
CUUGUUCU G UCCUUUUU
9352
AAAAAGGA GCCGAAAGGCGAGUGAGGUCU AGAACAAG
20782





5599
AAGAAAAU G UGUUUUUU
9354
AAAAAACA GCCGAAAGGCGAGUGAGGUCU AUUUUCUU
20783





5601
GAAAAUGU G UUUUUUGU
9355
ACAAAAAA GCCGAAAGGCGAGUGAGGUCU ACAUUUUC
20784





5608
UGUUUUUU G UUUGGUAC
9356
GUACCAAA GCCGAAAGGCGAGUGAGGUCU AAAAAACA
20785





5613
UUUGUUUG G UACCAUAG
9357
CUAUGGUA GCCGAAAGGCGAGUGAGGUCU CAAACAAA
20786





5621
GUACCAUA G UGUGAAAU
9360
AUUUCACA GCCGAAAGGCGAGUGAGGUCU UAUGGUAC
20787





5623
ACCAUAGU G UGAAAUGC
9361
GCAUUUCA GCCGAAAGGCGAGUGAGGUCU ACUAUGGU
20788





5630
UGUGAAAU G CUGGGAAC
9363
GUUCCCAG GCCGAAAGGCGAGUGAGGUCU AUUUCACA
20789





5655
UAAGACAU G CUAUGGCA
9370
UGCCAUAG GCCGAAAGGCGAGUGAGGUCU AUGUCUCA
20790





5661
AUGCUAUG G CACAUAUA
9372
UAUAUGUG GCCGAAAGGCGAGUGAGGUCU CAUAGCAU
20791





5676
UAUUUAUA G UCUGUCCA
9378
UAAACAGA GCCGAAAGGCGAGUGAGGUCU UAUAAAUA
20792





5680
UAUAGUCU G UUUAUGUA
9379
UACAUAAA GCCGAAAGGCGAGUGAGGUCU AGACUAUA
20793





5686
CUGUUUAU G UAGAAACA
9381
UGUUUCUA GCCGAAAGGCGAGUGAGGUCU AUAAACAG
20794





5698
AAACAAAU G UAAUAUAU
9384
AUAUAUUA GCCGAAAGGCGAGUGAGGUCU AUUUGUUU
20795





5711
AUAUUAAA G CCUUAUAU
9388
AUAUAAGG GCCGAAAGGCGAGUGAGGUCU UUUAAUAU
20796





5732
UGAACUUU G UACUAUUC
9394
GAAUAGUA GCCGAAAGGCGAGUGAGGUCU AAAGUUCA
20797





5748
CACAUUUU G UAUCAGUA
9399
UACUGAUA GCCGAAAGGCGAGUGAGGUCU AAAAUGUG
20798





5754
UUGUAUCA G UAUUAUGU
9401
ACAUAAUA GCCGAAAGGCGAGUGAGGUCU UGAUACAA
20799





5761
AGUAUUAU G UAGCAUAA
9404
UUAUGCUA GCCGAAAGGCGAGUGAGGUCU AUAAUACU
20800





5764
AUUAUGUA G CAUAACAA
9405
UUGUUAUG GCCGAAAGGCGAGUGAGGUCU UACAUAAU
20801





5775
UAACAAAG G UCAUAAUG
9408
CAUUAUGA GCCGAAAGGCGAGUGAGGUCU CUUUGUUA
20802





5783
GUCAUAAU G CUUUCAGC
9411
GCUGAAAG GCCGAAAGGCGAGUGAGGUCU AUCAUGAC
20803





5790
UGCUUUCA G CAAUUGAU
9412
AUCAAUUG GCCGAAAGGCGAGUGAGGUCU UGAAAGCA
20804





5799
CAAUUGAU G UCAUUUUA
9415
UAAAAUGA GCCGAAAGGCGAGUGAGGUCU AUCAAUUG
20805






Input Sequence = AF035121.




Cut Site = G/Y




Arm Length = 8.




Core Sequence = GCcgaaagGCGaGuCaaGGuCu




AF035121 (Homo sapiens KDR/flk-1 protein mRNA, complete cds.; Acc# AF035121; 5830 bp)








[0363]


Claims
  • 1. A compound having Formula II: (SEQ ID NO: 13488) 5′-usascs asau ucU GAu Gag gcg aaa gcc Gaa Aag aca aB-3′ wherein each a is 2′-O-methyl adenosine nucleotide, each g is a 2′-O-methyl guanosine nucleotide, each c is a 2′-O-methyl cytidine nucleotide, each u is a 2′-O-methyl uridine nucleotide, each A is adenosine, each G is guanosine, each s individually represents a phosphorothioate internucleotide linkage, U is 2′-deoxy-2′-C-allyl uridine, and B is an inverted deoxyabasic moiety.
  • 2. A composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier or diluent.
  • 3. A method of administering to a cell the compound of claim 1 comprising contacting said cell with the compound under conditions suitable for said administration.
  • 4. The method of claim 3, wherein said cell is a mammalian cell.
  • 5. The method of claim 3, wherein said cell is a human cell.
  • 6. The method of claim 3, wherein said administration is in the presence of a delivery reagent.
  • 7. The method of claim 6, wherein said delivery reagent is a lipid.
  • 8. The method of claim 7, wherein said lipid is a cationic lipid.
  • 9. The method of claim 7, wherein said lipid is a phospholipid.
  • 10. The method of claim 6, wherein said delivery reagent is a liposome.
  • 11. A method of administering to a cell the compound of claim 1 in conjunction with one or more other known drugs comprising contacting said cell with the compound and the other known drug under conditions suitable for said administration.
  • 12. A method of inhibiting ocular angiogenesis in a patient comprising the step of contacting said patient with the compound of claim 1 under conditions suitable for said inhibition.
  • 13. The method of claim 11, wherein said angiogenesis is associated with diabetic retinopathy.
  • 14. The method of claim 11, wherein said angiogenesis is associated with age related diabetic retinopathy.
  • 15. A method of cleaving RNA comprising a sequence of KDR RNA comprising contacting the compound of claim 1 with said RNA under conditions suitable for the cleavage of said RNA.
  • 16. The method of claim 14, wherein said cleavage is carried out in the presence of a divalent cation.
  • 17. The method of claim 15, wherein said divalent cation is Mg2+.
  • 18. A method of administering to a mammal the compound of claim 1 comprising contacting said mammal with the compound under conditions suitable for said administration.
  • 19. The method of claim 17, wherein said mammal is a human.
  • 20. The method of claim 17 wherein said administration is in the presence of a delivery reagent.
  • 21. The method of claim 17, wherein said delivery reagent is a lipid.
  • 22. The method of claim 20, wherein said lipid is a cationic lipid.
  • 23. The method of claim 20, wherein said lipid is a phospholipid.
  • 24. The method of claim 19, wherein said delivery reagent is a liposome.
Parent Case Info

[0001] This patent application is a continuation-in-part of Pavco et al., U.S. Ser. No. 09/870,161, filed May 29, 2001, which is a continuation-in-part of Pavco et al., U.S. Ser. No. 09/708,690, filed Nov. 7, 2000, which is a continuation-in-part of Pavco et al., U.S. Ser. No. 09/371,722, filed Aug. 10, 1999, which is a continuation-in-part of Pavco et al., U.S. Ser. No. 08/584,040, filed Jan. 11, 1996, which claims the benefit of Pavco et al., U.S. S No. 60/005,974, filed on Oct. 26, 1995, all of these earlier applications are entitled “Method and Reagent for Treatment of Diseases or Conditions Related To Levels of Vascular Endothelial Growth Factor Receptor”. Each of these applications is hereby incorporated by reference herein in its entirety including the drawings and tables.

Provisional Applications (1)
Number Date Country
60005974 Oct 1995 US
Continuation in Parts (4)
Number Date Country
Parent 09870161 May 2001 US
Child 10138674 May 2002 US
Parent 09708690 Nov 2000 US
Child 09870161 May 2001 US
Parent 09371722 Aug 1999 US
Child 09708690 Nov 2000 US
Parent 08584040 Jan 1996 US
Child 09371722 Aug 1999 US